-
1
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-κB pathways by diverse genetic abnormalities in multiple myeloma
-
Annunziata C.M., Davis R.E., Demchenko Y., Bellamy W., Gabrea A., Zhan F., Lenz G., Hanamura I., Wright G., Xiao W., Dave S., Hurt E.M., Tan B., Zhao H., Stephens O., Santra M., Williams D.R., Dang L., Barlogie B., Shaughnessy Jr. J.D., Kuehl W.M., and Staudt L.M. Frequent engagement of the classical and alternative NF-κB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell. 12 2 (2007) 115-130
-
(2007)
Cancer Cell.
, vol.12
, Issue.2
, pp. 115-130
-
-
Annunziata, C.M.1
Davis, R.E.2
Demchenko, Y.3
Bellamy, W.4
Gabrea, A.5
Zhan, F.6
Lenz, G.7
Hanamura, I.8
Wright, G.9
Xiao, W.10
Dave, S.11
Hurt, E.M.12
Tan, B.13
Zhao, H.14
Stephens, O.15
Santra, M.16
Williams, D.R.17
Dang, L.18
Barlogie, B.19
Shaughnessy Jr., J.D.20
Kuehl, W.M.21
Staudt, L.M.22
more..
-
2
-
-
9144275033
-
Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers
-
Bonizzi G., Bebien M., Otero D.C., Johnson-Vroom K.E., Cao Y., Vu D., Jegga A.G., Aronow B.J., Ghosh G., Rickert R.C., and Karin M. Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO J. 23 21 (2004) 4202-4210
-
(2004)
EMBO J.
, vol.23
, Issue.21
, pp. 4202-4210
-
-
Bonizzi, G.1
Bebien, M.2
Otero, D.C.3
Johnson-Vroom, K.E.4
Cao, Y.5
Vu, D.6
Jegga, A.G.7
Aronow, B.J.8
Ghosh, G.9
Rickert, R.C.10
Karin, M.11
-
3
-
-
0035475338
-
Tumor necrosis factor receptor-associated factors (TRAFs)
-
Bradley J.R., and Pober J.S. Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene 20 (2001) 6482-6491
-
(2001)
Oncogene
, vol.20
, pp. 6482-6491
-
-
Bradley, J.R.1
Pober, J.S.2
-
4
-
-
0033725155
-
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
-
Devin A., Cook A., Lin Y., Rodriguez Y., Kelliher M., and Liu Z. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. Immunity 12 (2000) 419-429
-
(2000)
Immunity
, vol.12
, pp. 419-429
-
-
Devin, A.1
Cook, A.2
Lin, Y.3
Rodriguez, Y.4
Kelliher, M.5
Liu, Z.6
-
5
-
-
1542380581
-
Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB
-
Habelhah H., Takahashi S., Cho S.G., Kadoya T., Watanabe T., and Ronai Z. Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB. EMBO J. 23 (2004) 322-332
-
(2004)
EMBO J.
, vol.23
, pp. 322-332
-
-
Habelhah, H.1
Takahashi, S.2
Cho, S.G.3
Kadoya, T.4
Watanabe, T.5
Ronai, Z.6
-
6
-
-
39049183044
-
Regulation and function of IKK and IKK related-kinases
-
Hacker H., and Karin M. Regulation and function of IKK and IKK related-kinases. Sci. STKE (2006) re13
-
(2006)
Sci. STKE
-
-
Hacker, H.1
Karin, M.2
-
7
-
-
33750435582
-
NF-κB and the immune response
-
Hayden M.S., West A.P., and Ghosh S. NF-κB and the immune response. Oncogene 25 (2006) 6758-6780
-
(2006)
Oncogene
, vol.25
, pp. 6758-6780
-
-
Hayden, M.S.1
West, A.P.2
Ghosh, S.3
-
8
-
-
14544286868
-
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs
-
Hauer J., Puschner S., Ramakrishnan P., Simon U., Bongers M., Federle C., and Engelmann H. TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 2874-2879
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 2874-2879
-
-
Hauer, J.1
Puschner, S.2
Ramakrishnan, P.3
Simon, U.4
Bongers, M.5
Federle, C.6
Engelmann, H.7
-
9
-
-
0034543631
-
Expression of the tumor necrosis factor receptor-associated factors (TRAFs) 1 and 2 is a characteristic feature of Hodgkin and Reed-Sternberg cells
-
Izban K.F., Ergin M., Martinez R.L., and Alkan S. Expression of the tumor necrosis factor receptor-associated factors (TRAFs) 1 and 2 is a characteristic feature of Hodgkin and Reed-Sternberg cells. Mod. Pathol. 13 12 (2000) 1324-1331
-
(2000)
Mod. Pathol.
, vol.13
, Issue.12
, pp. 1324-1331
-
-
Izban, K.F.1
Ergin, M.2
Martinez, R.L.3
Alkan, S.4
-
10
-
-
0029983251
-
Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient
-
Kanzler H., Hansmann M.L., Kapp U., Wolf J., Diehl V., Rajewsky K., and Küppers R. Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient. Blood 87 8 (1996) 3429-3436
-
(1996)
Blood
, vol.87
, Issue.8
, pp. 3429-3436
-
-
Kanzler, H.1
Hansmann, M.L.2
Kapp, U.3
Wolf, J.4
Diehl, V.5
Rajewsky, K.6
Küppers, R.7
-
11
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma
-
Keats J.J., Fonseca R., Chesi M., Schop R., Baker A., Chng W.J., Van Wier S., Tiedemann R., Shi C.X., Sebag M., Braggio E., Henry T., Zhu Y.X., Fogle H., Price-Troska T., Ahmann G., Mancini C., Brents L.A., Kumar S., Greipp P., Dispenzieri A., Bryant B., Mulligan G., Bruhn L., Barrett M., Valdez R., Trent J., Stewart A.K., Carpten J., and Bergsagel P.L. Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma. Cancer Cell. 12 2 (2007) 131-144
-
(2007)
Cancer Cell.
, vol.12
, Issue.2
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
Schop, R.4
Baker, A.5
Chng, W.J.6
Van Wier, S.7
Tiedemann, R.8
Shi, C.X.9
Sebag, M.10
Braggio, E.11
Henry, T.12
Zhu, Y.X.13
Fogle, H.14
Price-Troska, T.15
Ahmann, G.16
Mancini, C.17
Brents, L.A.18
Kumar, S.19
Greipp, P.20
Dispenzieri, A.21
Bryant, B.22
Mulligan, G.23
Bruhn, L.24
Barrett, M.25
Valdez, R.26
Trent, J.27
Stewart, A.K.28
Carpten, J.29
Bergsagel, P.L.30
more..
-
12
-
-
54049133340
-
The RING domain and first zinc finger domain of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL
-
Lamothe B., Campos A.D., Webster W.K., Gopinathan A., Hur L., and Darnay B.G. The RING domain and first zinc finger domain of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL. J. Biol. Chem. 283 36 (2008) 24871-24880
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.36
, pp. 24871-24880
-
-
Lamothe, B.1
Campos, A.D.2
Webster, W.K.3
Gopinathan, A.4
Hur, L.5
Darnay, B.G.6
-
13
-
-
0034614656
-
Functional interaction of filamin and TNF-receptor associated factor 2 (TRAF2)
-
Leonardi A., Ellinger-Ziegelbauer H., Franzoso G., Brown K., and Siebenlist U. Functional interaction of filamin and TNF-receptor associated factor 2 (TRAF2). J. Biol. Chem. 275 (2000) 271-278
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 271-278
-
-
Leonardi, A.1
Ellinger-Ziegelbauer, H.2
Franzoso, G.3
Brown, K.4
Siebenlist, U.5
-
14
-
-
2942731516
-
Regulation of the NF-κB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation
-
Liao G., Zhang M., Harhaj E.W., and Sun S.C. Regulation of the NF-κB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation. J. Biol. Chem. 279 (2004) 26243-26250
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26243-26250
-
-
Liao, G.1
Zhang, M.2
Harhaj, E.W.3
Sun, S.C.4
-
15
-
-
33845498404
-
A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival
-
Sabbagh L., Srokowski C.C., Pulle G., Snell L.M., Sedgmen B.J., Liu Y., Tsitsikov E.N., and Watts T.H. A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival. Proc. Natl. Acad. Sci. U.S.A. 103 49 (2006) 18703-18708
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, Issue.49
, pp. 18703-18708
-
-
Sabbagh, L.1
Srokowski, C.C.2
Pulle, G.3
Snell, L.M.4
Sedgmen, B.J.5
Liu, Y.6
Tsitsikov, E.N.7
Watts, T.H.8
-
16
-
-
33750443289
-
IkappaB kinase complexes: gateways to NF-kappaB activation and transcription
-
Scheidereit C. IkappaB kinase complexes: gateways to NF-kappaB activation and transcription. Oncogene 25 (2006) 6685-6705
-
(2006)
Oncogene
, vol.25
, pp. 6685-6705
-
-
Scheidereit, C.1
-
17
-
-
0034752285
-
TRAF1 is a negative regulator of TNF signaling: enhanced TNF signaling in TRAF1-deficient mice
-
Tsitsikov E.N., Laouini D., Dunn I.F., Sannikova T.Y., Davidson L., Alt F.W., and Geha R.S. TRAF1 is a negative regulator of TNF signaling: enhanced TNF signaling in TRAF1-deficient mice. Immunity 15 (2001) 647-657
-
(2001)
Immunity
, vol.15
, pp. 647-657
-
-
Tsitsikov, E.N.1
Laouini, D.2
Dunn, I.F.3
Sannikova, T.Y.4
Davidson, L.5
Alt, F.W.6
Geha, R.S.7
-
18
-
-
56349164232
-
Non redundant and complementary function of TRAF2 and TRAF3 in a ubiquitation cascade that activates NIK-dependent alternative NF-kappaB signaling
-
Vallabhapurapu S., Matsuzawa A., Zhang W., Tseng P.H., Keats J.J., Wang H., Vignali D., Bergsagel P.L., and Karin M. Non redundant and complementary function of TRAF2 and TRAF3 in a ubiquitation cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat. Immunol. 9 12 (2008) 1364-1370
-
(2008)
Nat. Immunol.
, vol.9
, Issue.12
, pp. 1364-1370
-
-
Vallabhapurapu, S.1
Matsuzawa, A.2
Zhang, W.3
Tseng, P.H.4
Keats, J.J.5
Wang, H.6
Vignali, D.7
Bergsagel, P.L.8
Karin, M.9
-
19
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factor in the immune system
-
Vallabhapurapu S., and Karin M. Regulation and function of NF-kappaB transcription factor in the immune system. Ann. Rev. Immunol. 27 (2009) 693-733
-
(2009)
Ann. Rev. Immunol.
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
21
-
-
65049086930
-
Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1-TNFR2 cooperation
-
Wicovsky A., Henkler F., Salzmann S., Scheurich P., Kneitz C., and Wajant H. Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1-TNFR2 cooperation. Oncogene 28 15 (2009) 1769-1781
-
(2009)
Oncogene
, vol.28
, Issue.15
, pp. 1769-1781
-
-
Wicovsky, A.1
Henkler, F.2
Salzmann, S.3
Scheurich, P.4
Kneitz, C.5
Wajant, H.6
-
22
-
-
15844383634
-
Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells
-
Wolf J., Kapp U., Bohlen H., Kornacker M., Schoch C., Stahl B., Mücke S., von Kalle C., Fonatsch C., Schaefer H.E., Hansmann M.L., and Diehl V. Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells. Blood 87 8 (1996) 3418-3428
-
(1996)
Blood
, vol.87
, Issue.8
, pp. 3418-3428
-
-
Wolf, J.1
Kapp, U.2
Bohlen, H.3
Kornacker, M.4
Schoch, C.5
Stahl, B.6
Mücke, S.7
von Kalle, C.8
Fonatsch, C.9
Schaefer, H.E.10
Hansmann, M.L.11
Diehl, V.12
-
23
-
-
33747615237
-
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
-
Yamamoto M., Okamoto T., Takeda K., Sato S., Sanjo H., Uematsu S., Saitoh T., Yamamoto N., Sakurai H., Ishii K.J., Yamaoka S., Kawai T., Matsuura Y., Takeuchi O., and Akira S. Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling. Nat. Immunol. 7 (2006) 962-970
-
(2006)
Nat. Immunol.
, vol.7
, pp. 962-970
-
-
Yamamoto, M.1
Okamoto, T.2
Takeda, K.3
Sato, S.4
Sanjo, H.5
Uematsu, S.6
Saitoh, T.7
Yamamoto, N.8
Sakurai, H.9
Ishii, K.J.10
Yamaoka, S.11
Kawai, T.12
Matsuura, Y.13
Takeuchi, O.14
Akira, S.15
-
24
-
-
0034326624
-
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies
-
Zapata J.M., Krajewska M., Krajewski S., Kitada S., Welsh K., Monks A., McCloskey N., Gordon J., Kipps T., Goscoyne R.D., Shabaik A., and Reed J.C. TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies. J. Immunol. 165 (2000) 5084-5096
-
(2000)
J. Immunol.
, vol.165
, pp. 5084-5096
-
-
Zapata, J.M.1
Krajewska, M.2
Krajewski, S.3
Kitada, S.4
Welsh, K.5
Monks, A.6
McCloskey, N.7
Gordon, J.8
Kipps, T.9
Goscoyne, R.D.10
Shabaik, A.11
Reed, J.C.12
-
25
-
-
56349164239
-
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors c-IAP1-2, TRAF2 and TRAF3 and the kinase NIK
-
Zarnegar B.J., Wang Y., Mahoney D.J., Dempsey P.W., Cheung H.H., He J., Shiba T., Yang X., Yeh W., Mak T.W., Korneluk R.G., and Cheng G. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors c-IAP1-2, TRAF2 and TRAF3 and the kinase NIK. Nat. Immunol. 9 12 (2008) 1371-1378
-
(2008)
Nat. Immunol.
, vol.9
, Issue.12
, pp. 1371-1378
-
-
Zarnegar, B.J.1
Wang, Y.2
Mahoney, D.J.3
Dempsey, P.W.4
Cheung, H.H.5
He, J.6
Shiba, T.7
Yang, X.8
Yeh, W.9
Mak, T.W.10
Korneluk, R.G.11
Cheng, G.12
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