Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation

Nature Medicine

Volumn 22, Issue 10, 2016, Pages 1140-1150

  Stellos, Konstantinos ^a,b   Gatsiou, Aikaterini ^a,b   Stamatelopoulos, Kimon ^c   Perisic Matic, Ljubica ^d   John, David ^a,b   Lunella, Federica Francesca ^a,b   Jaé, Nicolas ^a,b   Rossbach, Oliver ^e   Amrhein, Carolin ^a   Sigala, Frangiska ^c   Boon, Reinier A ^a,b   Fürtig, Boris ^a   Manavski, Yosif ^a,b   You, Xintian ^f   Uchida, Shizuka ^a,b   Keller, Till ^a,b   Boeckel, Jes Niels ^a,b   Franco Cereceda, Anders ^d   Maegdefessel, Lars ^d,g   Chen, Wei ^f   Schwalbe, Harald ^a   Bindereif, Albrecht ^e   Eriksson, Per ^d   Hedin, Ulf ^d   Zeiher, Andreas M ^a,b   Dimmeler, Stefanie ^a,b   more..

^a GOETHE UNIVERSITY   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^c UNIVERSITY OF ATHENS   (Greece)

^d KAROLINSKA INSTITUTE   (Sweden)

^e JUSTUS LIEBIG UNIVERSITY   (Germany)

^f MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^g TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ANTIGEN; CATHEPSIN S; ELAV LIKE PROTEIN 1; GAMMA INTERFERON; HUMAN ANTIGEN R; INOSINE; MESSENGER RNA; RNA BINDING PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ADAR1 PROTEIN, HUMAN; ADENOSINE DEAMINASE; CATHEPSIN; ELAVL1 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ANGIOGENESIS; AORTA ANEURYSM; ARTICLE; ATHEROSCLEROSIS; CAROTID ATHEROSCLEROSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; INVERTED REPEAT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA EDITING; RNA STABILITY; ADULT; AGED; AORTIC ANEURYSM; CAROTID ARTERY DISEASE; DRUG EFFECTS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; GENETICS; HIGH THROUGHPUT SEQUENCING; IMMUNOBLOTTING; MALE; METABOLISM; MIDDLE AGED; REAL TIME POLYMERASE CHAIN REACTION; RNA PROCESSING; SEQUENCE ANALYSIS; UMBILICAL VEIN ENDOTHELIAL CELL; VERY ELDERLY;

3' UNTRANSLATED REGIONS; ADENOSINE; ADENOSINE DEAMINASE; ADULT; AGED; AGED, 80 AND OVER; AORTIC ANEURYSM; ATHEROSCLEROSIS; CAROTID ARTERY DISEASES; CATHEPSINS; CORONARY ARTERY DISEASE; ELAV-LIKE PROTEIN 1; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENE KNOCK-IN TECHNIQUES; GENE KNOCKDOWN TECHNIQUES; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOXIA; IMMUNOBLOTTING; INOSINE; INTERFERON-GAMMA; MALE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RNA EDITING; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; RNA-BINDING PROTEINS; SEQUENCE ANALYSIS, RNA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84987648062     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4172     Document Type: Article

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