Regulation of alternative splicing by RNA editing

Nature

Volumn 399, Issue 6731, 1999, Pages 75-80

  Rueter, Susan M ^a   Dawson, T Renee ^a   Emeson, Ronald B ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE RNA SPLICING; ARTICLE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATORY MECHANISM; RNA PROCESSING; RNA SEQUENCE;

ADENOSINE; ADENOSINE DEAMINASE; ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; CELL LINE; DNA; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GUANOSINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RATS; RNA EDITING; RNA, MESSENGER; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033529064     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/19992     Document Type: Article

References (27)

1. Rueter, S. & Emeson, R. in Modification and Editing of RNA (eds Grosjean, H. & Benne, R.) 343-361 (ASM, Washington DC, 1998).
2. Melcher, T. et al. A mammalian RNA editing enzyme. Nature 379, 460-464 (1996).
3. O'Connell, M. A, Gerber, A. & Keller, W. Purification, of human double-stranded RNA-specific editase 1 (hRED1) involved is editing of brain glutamate receptor B pre-mRNA. J. Biol. Chem. 272, 473-478 (1997).
4. Bass, B. L. et al. A standardized nomenclature for adenosine deaminases that act on RNA. RNA 3, 947-949 (1997).
5. Gerber, A., O'Connell, M. A. & Keller, W. Two forms of human double-stranded RNA-specific editase 1 (hRED1) generated by the insertion of an Alu cassette. RNA 3, 453-463 (1997).
6. Lai, F., Chen, C. X., Carter, K. C. & Nishikura, K. Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases. Mol. Cell. Biol. 17, 2413-2424 (1997).
7. Lai, F., Drakas, R. & Nishikura, K. Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcripts. J. Biol. Chem. 270, 17096-17105 (1995).
8. Maas, S. et al. Structural requirements for RNA editing in glutamate receptor pre-mRNAs by recombinant double-stranded RNA adenosine deaminase. J. Biol. Chem. 271, 12221-12226 (1996).
9. Burns, C. M. et al. Regulation of zerotonin·2C receptor G-protein coupling by RNA editing. Nature 387, 303-308 (1997).
10. Farabaugh, P. J. Programmed translational frameshifting. Microbiol. Rev. 60, 103-134 (1996).
11. Calligaris, R., Bottardi, S., Cogoi, S., Aperteguia I. & Santonro, C. Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factor. Proc. Natl Acad. Sci. USA 92, 11598-11602 (1995).
12. Schreiber, E., Matthias, P., Muller M. M. & Schaffner, W. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17, 6419 (1989).
13. Kim, U., Wang, Y., Sanford, T., Zeng, Y. & Nishikura, K. Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. Proc. Natl Acad. Sci. USA 91, 11457-11461 (1994).
14. O'Connell, M. A. et al. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. Mol. Cell Biol. 15, 1389-1397 (1995).
15. Kozak, M. An analysis of vertebrate mRNA sequences: intimations of translational control. J. Cell Biol. 115, 887-903 (1991).
16. Melcher, T. et al. RED2, a brain-specific member of the RNA-specific adenosine deaminase family. J. Biol. Chem. 271, 31795-31798 (1996).
17. Mount, S. M. A catalogue of splice junction sequences. Nucleic Acids Res. 10, 459-472 (1982).
18. Jackson, I. J. A reappraisal of non-consensus mRNA splice sites. Nucleic Acids Res. 19, 3795-3798 (1991).
19. Reed, R. The organization of 3′ splice-site sequences in mammalian introns. Genes Dev. 3, 2113-2123 (1989).
20. Deirdre, A., Scadden, I. & Smith, C. W. Interactions between the terminal bases of mammalian introns are retained in inosine-containing pre-mRNAs. EMBO J. 14, 3236-3246 (1995).
21. Tarn, W. Y. Site-specific substitution of inosine at the terminal positions of a pre-mRNA intron: implications for the configuration of the terminal base interaction. Biochimie 78, 1057-1065 (1996).
22. Zuker, M. Prediction of RNA secondary structure by energy minimization. Methods Mol. Biol. 25, 267-294 (1994).
23. Rechsteiner, M. & Rogers, S. W. PEST sequences and regulation by proteolysis. Trends Biochem. Sci 21, 267-271 (1996).
24. Current Protocols in Molecular Biology (eds Ausubel, F. et al.) (Wiley, New York, 1989).
25. Rueter, S. M., Burns, C. M., Coode, S. A., Mookherjee, P. & Emeson, R. B. Glutamate receptor RNA editing in vitro by enzymatic conversion of adenosine to inosine. Science 267, 1491-1494 (1995).
26. Emeson, R. B., Hedjran, F., Yeakley, J. M., Guise, J. W. & Rosenfeld, M. G. Alternative production of calcitonin and CGRP mRNA is regulated at tile calcitonin-specific splice acceptor. Nature 341, 76-80 (1989).
27. Kunkel, T. A. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl Acad. Sci. USA 82, 488-492 (1985).