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Volumn 279, Issue 3, 2016, Pages 293-308

Gene expression signatures, pathways and networks in carotid atherosclerosis

Author keywords

Atherosclerosis; Carotid plaques; Gene expression; Microarrays

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 26A1; CYTOCHROME P450 2B6; GELATINASE B; HEMOGLOBIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LMOD1 PROTEIN; MACROPHAGE ELASTASE; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MALAT1 PROTEIN; MIR155HG PROTEIN; NITRIC OXIDE; PLIN2 PROTEIN; PROTEIN; SYNPO2 PROTEIN; TP53TG PROTEIN; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG; TRANSCRIPTOME;

EID: 84958933712     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/joim.12448     Document Type: Article
Times cited : (103)

References (71)
  • 1
    • 79956319051 scopus 로고    scopus 로고
    • Progress and challenges in translating the biology of atherosclerosis
    • Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature 2011; 473: 317-25.
    • (2011) Nature , vol.473 , pp. 317-325
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 2
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005; 352: 1685-95.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 3
    • 1042300322 scopus 로고    scopus 로고
    • Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery
    • Rothwell PM, Eliasziw M, Gutnikov SA, Warlow CP, Barnett HJ; Carotid Endarterectomy Trialists C. Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery. Lancet 2004; 363: 915-24.
    • (2004) Lancet , vol.363 , pp. 915-924
    • Rothwell, P.M.1    Eliasziw, M.2    Gutnikov, S.A.3    Warlow, C.P.4    Barnett, H.J.5
  • 4
    • 36148978582 scopus 로고    scopus 로고
    • Risk of stroke early after transient ischaemic attack: a systematic review and meta-analysis
    • Giles MF, Rothwell PM. Risk of stroke early after transient ischaemic attack: a systematic review and meta-analysis. Lancet Neurol 2007; 6: 1063-72.
    • (2007) Lancet Neurol , vol.6 , pp. 1063-1072
    • Giles, M.F.1    Rothwell, P.M.2
  • 5
    • 39349100176 scopus 로고    scopus 로고
    • Prediction and prevention of stroke in patients with symptomatic carotid stenosis: the high-risk period and the high-risk patient
    • Rothwell PM. Prediction and prevention of stroke in patients with symptomatic carotid stenosis: the high-risk period and the high-risk patient. Eur J Vasc Endovasc Surg 2008; 35: 255-63.
    • (2008) Eur J Vasc Endovasc Surg , vol.35 , pp. 255-263
    • Rothwell, P.M.1
  • 6
    • 33744992900 scopus 로고    scopus 로고
    • Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms: the Oxford plaque study
    • Redgrave JN, Lovett JK, Gallagher PJ, Rothwell PM. Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms: the Oxford plaque study. Circulation 2006; 113: 2320-8.
    • (2006) Circulation , vol.113 , pp. 2320-2328
    • Redgrave, J.N.1    Lovett, J.K.2    Gallagher, P.J.3    Rothwell, P.M.4
  • 7
    • 0035916233 scopus 로고    scopus 로고
    • Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization
    • Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, Nilsson J. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 2001; 103: 926-33.
    • (2001) Circulation , vol.103 , pp. 926-933
    • Crisby, M.1    Nordin-Fredriksson, G.2    Shah, P.K.3    Yano, J.4    Zhu, J.5    Nilsson, J.6
  • 9
    • 0034659898 scopus 로고    scopus 로고
    • Genomics, gene expression and DNA arrays
    • Lockhart DJ, Winzeler EA. Genomics, gene expression and DNA arrays. Nature 2000; 405: 827-36.
    • (2000) Nature , vol.405 , pp. 827-836
    • Lockhart, D.J.1    Winzeler, E.A.2
  • 10
    • 0036840612 scopus 로고    scopus 로고
    • Changes in gene expression in atherosclerotic plaques analyzed using DNA array
    • Hiltunen MO, Tuomisto TT, Niemi M et al. Changes in gene expression in atherosclerotic plaques analyzed using DNA array. Atherosclerosis 2002; 165: 23-32.
    • (2002) Atherosclerosis , vol.165 , pp. 23-32
    • Hiltunen, M.O.1    Tuomisto, T.T.2    Niemi, M.3
  • 11
    • 33847670874 scopus 로고    scopus 로고
    • Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques
    • Ijas P, Nuotio K, Saksi J et al. Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques. Arterioscler Thromb Vasc Biol 2007; 27: 154-60.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 154-160
    • Ijas, P.1    Nuotio, K.2    Saksi, J.3
  • 12
    • 0142228253 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in coronary atherosclerotic plaques from patients with stable or unstable angina by cDNA array analysis
    • Randi AM, Biguzzi E, Falciani F et al. Identification of differentially expressed genes in coronary atherosclerotic plaques from patients with stable or unstable angina by cDNA array analysis. J Thromb Haemost 2003; 1: 829-35.
    • (2003) J Thromb Haemost , vol.1 , pp. 829-835
    • Randi, A.M.1    Biguzzi, E.2    Falciani, F.3
  • 13
    • 0037436835 scopus 로고    scopus 로고
    • Differential gene expression in primary and recurrent carotid stenosis
    • Woodside KJ, Hernandez A, Smith FW et al. Differential gene expression in primary and recurrent carotid stenosis. Biochem Biophys Res Commun 2003; 302: 509-14.
    • (2003) Biochem Biophys Res Commun , vol.302 , pp. 509-514
    • Woodside, K.J.1    Hernandez, A.2    Smith, F.W.3
  • 14
    • 80755153690 scopus 로고    scopus 로고
    • Gene expression differences between stroke-associated and asymptomatic carotid plaques
    • Saksi J, Ijas P, Nuotio K et al. Gene expression differences between stroke-associated and asymptomatic carotid plaques. J Mol Med 2011; 89: 1015-26.
    • (2011) J Mol Med , vol.89 , pp. 1015-1026
    • Saksi, J.1    Ijas, P.2    Nuotio, K.3
  • 15
    • 34548079864 scopus 로고    scopus 로고
    • Dead or alive: gene expression profiles of advanced atherosclerotic plaques from autopsy and surgery
    • Sluimer JC, Kisters N, Cleutjens KB et al. Dead or alive: gene expression profiles of advanced atherosclerotic plaques from autopsy and surgery. Physiol Genomics 2007; 30: 335-41.
    • (2007) Physiol Genomics , vol.30 , pp. 335-341
    • Sluimer, J.C.1    Kisters, N.2    Cleutjens, K.B.3
  • 16
    • 84880152633 scopus 로고    scopus 로고
    • Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy
    • Folkersen L, Persson J, Ekstrand J et al. Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy. Mol Med 2012; 18: 669-75.
    • (2012) Mol Med , vol.18 , pp. 669-675
    • Folkersen, L.1    Persson, J.2    Ekstrand, J.3
  • 17
    • 84897379124 scopus 로고    scopus 로고
    • Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation
    • Miller CL, Haas U, Diaz R et al. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. PLoS Genet 2014; 10: e1004263.
    • (2014) PLoS Genet , vol.10 , pp. e1004263
    • Miller, C.L.1    Haas, U.2    Diaz, R.3
  • 18
    • 84896744423 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis
    • Kojima Y, Downing K, Kundu R et al. Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis. J Clin Investig 2014; 124: 1083-97.
    • (2014) J Clin Investig , vol.124 , pp. 1083-1097
    • Kojima, Y.1    Downing, K.2    Kundu, R.3
  • 19
    • 84865361983 scopus 로고    scopus 로고
    • Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization
    • Smedbakken LM, Halvorsen B, Daissormont I et al. Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization. Atherosclerosis 2012; 224: 266-73.
    • (2012) Atherosclerosis , vol.224 , pp. 266-273
    • Smedbakken, L.M.1    Halvorsen, B.2    Daissormont, I.3
  • 20
    • 84865263402 scopus 로고    scopus 로고
    • Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation
    • Salagianni M, Galani IE, Lundberg AM et al. Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation. Circulation 2012; 126: 952-62.
    • (2012) Circulation , vol.126 , pp. 952-962
    • Salagianni, M.1    Galani, I.E.2    Lundberg, A.M.3
  • 21
    • 84885068480 scopus 로고    scopus 로고
    • Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis
    • Perisic L, Hedin E, Razuvaev A et al. Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis. Arterioscler Thromb Vasc Biol 2013; 33: 2432-43.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 2432-2443
    • Perisic, L.1    Hedin, E.2    Razuvaev, A.3
  • 22
    • 84155172981 scopus 로고    scopus 로고
    • The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation
    • Wang J, Razuvaev A, Folkersen L et al. The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation. Atherosclerosis 2012; 220: 102-9.
    • (2012) Atherosclerosis , vol.220 , pp. 102-109
    • Wang, J.1    Razuvaev, A.2    Folkersen, L.3
  • 23
    • 81755184339 scopus 로고    scopus 로고
    • Correlations between clinical variables and gene-expression profiles in carotid plaque instability
    • Razuvaev A, Ekstrand J, Folkersen L et al. Correlations between clinical variables and gene-expression profiles in carotid plaque instability. Eur J Vasc Endovasc Surg 2011; 42: 722-30.
    • (2011) Eur J Vasc Endovasc Surg , vol.42 , pp. 722-730
    • Razuvaev, A.1    Ekstrand, J.2    Folkersen, L.3
  • 24
    • 78651106820 scopus 로고    scopus 로고
    • Expression of fatty acid-binding protein 4/aP2 is correlated with plaque instability in carotid atherosclerosis
    • Agardh HE, Folkersen L, Ekstrand J et al. Expression of fatty acid-binding protein 4/aP2 is correlated with plaque instability in carotid atherosclerosis. J Intern Med 2011; 269: 200-10.
    • (2011) J Intern Med , vol.269 , pp. 200-210
    • Agardh, H.E.1    Folkersen, L.2    Ekstrand, J.3
  • 25
    • 79953047839 scopus 로고    scopus 로고
    • 12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms
    • Gertow K, Nobili E, Folkersen L et al. 12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms. Atherosclerosis 2011; 215: 411-6.
    • (2011) Atherosclerosis , vol.215 , pp. 411-416
    • Gertow, K.1    Nobili, E.2    Folkersen, L.3
  • 26
    • 84883851219 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in T cells promotes stabilization of atherosclerotic plaques through an interleukin-17-dependent pathway
    • 196ra00
    • Gistera A, Robertson AK, Andersson J et al. Transforming growth factor-beta signaling in T cells promotes stabilization of atherosclerotic plaques through an interleukin-17-dependent pathway. Sci Transl Med 2013; 5: 196ra00.
    • (2013) Sci Transl Med , vol.5
    • Gistera, A.1    Robertson, A.K.2    Andersson, J.3
  • 27
    • 77956460552 scopus 로고    scopus 로고
    • Thromboxane synthase expression and thromboxane A2 production in the atherosclerotic lesion
    • Gabrielsen A, Qiu H, Back M et al. Thromboxane synthase expression and thromboxane A2 production in the atherosclerotic lesion. J Mol Med 2010; 88: 795-806.
    • (2010) J Mol Med , vol.88 , pp. 795-806
    • Gabrielsen, A.1    Qiu, H.2    Back, M.3
  • 28
    • 64149108811 scopus 로고    scopus 로고
    • Genetic variants of TNFSF4 and risk for carotid artery disease and stroke
    • Olofsson PS, Soderstrom LA, Jern C et al. Genetic variants of TNFSF4 and risk for carotid artery disease and stroke. J Mol Med 2009; 87: 337-46.
    • (2009) J Mol Med , vol.87 , pp. 337-346
    • Olofsson, P.S.1    Soderstrom, L.A.2    Jern, C.3
  • 29
    • 84871384293 scopus 로고    scopus 로고
    • Increased expression of heparanase in symptomatic carotid atherosclerosis
    • Osterholm C, Folkersen L, Lengquist M et al. Increased expression of heparanase in symptomatic carotid atherosclerosis. Atherosclerosis 2013; 226: 67-73.
    • (2013) Atherosclerosis , vol.226 , pp. 67-73
    • Osterholm, C.1    Folkersen, L.2    Lengquist, M.3
  • 30
    • 84911434770 scopus 로고    scopus 로고
    • The collagen cross-linking enzyme lysyl oxidase is associated with the healing of human atherosclerotic lesions
    • Ovchinnikova OA, Folkersen L, Persson J et al. The collagen cross-linking enzyme lysyl oxidase is associated with the healing of human atherosclerotic lesions. J Intern Med 2014; 276: 525-36.
    • (2014) J Intern Med , vol.276 , pp. 525-536
    • Ovchinnikova, O.A.1    Folkersen, L.2    Persson, J.3
  • 31
    • 84869501719 scopus 로고    scopus 로고
    • High plasma adiponectin concentration is associated with all-cause mortality in patients with carotid atherosclerosis
    • Persson J, Folkersen L, Ekstrand J et al. High plasma adiponectin concentration is associated with all-cause mortality in patients with carotid atherosclerosis. Atherosclerosis 2012; 225: 491-6.
    • (2012) Atherosclerosis , vol.225 , pp. 491-496
    • Persson, J.1    Folkersen, L.2    Ekstrand, J.3
  • 32
    • 0034074733 scopus 로고    scopus 로고
    • Critical appraisal of the design and reporting of studies of imaging and measurement of carotid stenosis
    • Rothwell PM, Pendlebury ST, Wardlaw J, Warlow CP. Critical appraisal of the design and reporting of studies of imaging and measurement of carotid stenosis. Stroke 2000; 31: 1444-50.
    • (2000) Stroke , vol.31 , pp. 1444-1450
    • Rothwell, P.M.1    Pendlebury, S.T.2    Wardlaw, J.3    Warlow, C.P.4
  • 33
    • 77957189028 scopus 로고    scopus 로고
    • 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial
    • Halliday A, Harrison M, Hayter E et al. 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial. Lancet 2010; 376: 1074-84.
    • (2010) Lancet , vol.376 , pp. 1074-1084
    • Halliday, A.1    Harrison, M.2    Hayter, E.3
  • 34
    • 84872347539 scopus 로고    scopus 로고
    • An open-source software program for performing Bonferroni and related corrections for multiple comparisons
    • Lesack K, Naugler C. An open-source software program for performing Bonferroni and related corrections for multiple comparisons. J Pathol Inform 2011; 2: 52.
    • (2011) J Pathol Inform , vol.2 , pp. 52
    • Lesack, K.1    Naugler, C.2
  • 35
    • 70849131666 scopus 로고    scopus 로고
    • ArrayMining: a modular web-application for microarray analysis combining ensemble and consensus methods with cross-study normalization
    • Glaab E, Garibaldi JM, Krasnogor N. ArrayMining: a modular web-application for microarray analysis combining ensemble and consensus methods with cross-study normalization. BMC Bioinformatics 2009; 10: 358.
    • (2009) BMC Bioinformatics , vol.10 , pp. 358
    • Glaab, E.1    Garibaldi, J.M.2    Krasnogor, N.3
  • 39
    • 79959258968 scopus 로고    scopus 로고
    • Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems
    • Le Cao KA, Boitard S, Besse P. Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems. BMC Bioinformatics 2011; 12: 253.
    • (2011) BMC Bioinformatics , vol.12 , pp. 253
    • Le Cao, K.A.1    Boitard, S.2    Besse, P.3
  • 40
    • 33746826203 scopus 로고    scopus 로고
    • Novel candidate genes in unstable areas of human atherosclerotic plaques
    • Papaspyridonos M, Smith A, Burnand KG et al. Novel candidate genes in unstable areas of human atherosclerotic plaques. Arterioscler Thromb Vasc Biol 2006; 26: 1837-44.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1837-1844
    • Papaspyridonos, M.1    Smith, A.2    Burnand, K.G.3
  • 41
    • 4944220700 scopus 로고    scopus 로고
    • ACST: which subgroups will benefit most from carotid endarterectomy?
    • author reply 5-6.
    • Rothwell PM. ACST: which subgroups will benefit most from carotid endarterectomy? Lancet 2004; 364: 1122-3; author reply 5-6.
    • (2004) Lancet , vol.364 , pp. 1122-1123
    • Rothwell, P.M.1
  • 42
    • 77956927823 scopus 로고    scopus 로고
    • The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation
    • Tripathi V, Ellis JD, Shen Z et al. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol Cell 2010; 39: 925-38.
    • (2010) Mol Cell , vol.39 , pp. 925-938
    • Tripathi, V.1    Ellis, J.D.2    Shen, Z.3
  • 43
    • 84899993786 scopus 로고    scopus 로고
    • Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth
    • Michalik KM, You X, Manavski Y et al. Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth. Circ Res 2014; 114: 1389-97.
    • (2014) Circ Res , vol.114 , pp. 1389-1397
    • Michalik, K.M.1    You, X.2    Manavski, Y.3
  • 44
    • 84862777104 scopus 로고    scopus 로고
    • RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings
    • Ren S, Peng Z, Mao JH et al. RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings. Cell Res 2012; 22: 806-21.
    • (2012) Cell Res , vol.22 , pp. 806-821
    • Ren, S.1    Peng, Z.2    Mao, J.H.3
  • 45
    • 0031880105 scopus 로고    scopus 로고
    • Isolation of a novel TP53 target gene from a colon cancer cell line carrying a highly regulated wild-type TP53 expression system
    • Takei Y, Ishikawa S, Tokino T, Muto T, Nakamura Y. Isolation of a novel TP53 target gene from a colon cancer cell line carrying a highly regulated wild-type TP53 expression system. Genes Chromosom Cancer 1998; 23: 1-9.
    • (1998) Genes Chromosom Cancer , vol.23 , pp. 1-9
    • Takei, Y.1    Ishikawa, S.2    Tokino, T.3    Muto, T.4    Nakamura, Y.5
  • 46
    • 84872612674 scopus 로고    scopus 로고
    • Histologically unstable asymptomatic carotid plaques have altered expression of genes involved in chemokine signalling leading to localised plaque inflammation and rupture
    • Salem MK, Vijaynagar B, Sayers RD et al. Histologically unstable asymptomatic carotid plaques have altered expression of genes involved in chemokine signalling leading to localised plaque inflammation and rupture. Eur J Vasc Endovasc Surg 2013; 45: 121-7.
    • (2013) Eur J Vasc Endovasc Surg , vol.45 , pp. 121-127
    • Salem, M.K.1    Vijaynagar, B.2    Sayers, R.D.3
  • 47
    • 24944591120 scopus 로고    scopus 로고
    • Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase
    • Song BL, Sever N, DeBose-Boyd RA. Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase. Mol Cell 2005; 19: 829-40.
    • (2005) Mol Cell , vol.19 , pp. 829-840
    • Song, B.L.1    Sever, N.2    DeBose-Boyd, R.A.3
  • 48
    • 0034188762 scopus 로고    scopus 로고
    • Pleiotropic effects of statins
    • Farmer JA. Pleiotropic effects of statins. Curr Atheroscler Rep 2000; 2: 208-17.
    • (2000) Curr Atheroscler Rep , vol.2 , pp. 208-217
    • Farmer, J.A.1
  • 49
    • 77949914720 scopus 로고    scopus 로고
    • Systematic review on the association between calcification in carotid plaques and clinical ischemic symptoms
    • Kwee RM. Systematic review on the association between calcification in carotid plaques and clinical ischemic symptoms. J Vasc Surg 2010; 51: 1015-25.
    • (2010) J Vasc Surg , vol.51 , pp. 1015-1025
    • Kwee, R.M.1
  • 50
    • 84868128043 scopus 로고    scopus 로고
    • Progression of vascular calcification is increased with statin use in the Veterans Affairs Diabetes Trial (VADT)
    • Saremi A, Bahn G, Reaven PD, Investigators V. Progression of vascular calcification is increased with statin use in the Veterans Affairs Diabetes Trial (VADT). Diabetes Care 2012; 35: 2390-2.
    • (2012) Diabetes Care , vol.35 , pp. 2390-2392
    • Saremi, A.1    Bahn, G.2    Reaven, P.D.3    Investigators, V.4
  • 52
    • 1842863965 scopus 로고    scopus 로고
    • Hyperlipidemia promotes osteoclastic potential of bone marrow cells ex vivo
    • Tintut Y, Morony S, Demer LL. Hyperlipidemia promotes osteoclastic potential of bone marrow cells ex vivo. Arterioscler Thromb Vasc Biol 2004; 24: e6-10.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. e6-10
    • Tintut, Y.1    Morony, S.2    Demer, L.L.3
  • 53
    • 58849102557 scopus 로고    scopus 로고
    • Carotid atherosclerotic plaques stabilize after stroke: insights into the natural process of atherosclerotic plaque stabilization
    • Peeters W, Hellings WE, de Kleijn DP et al. Carotid atherosclerotic plaques stabilize after stroke: insights into the natural process of atherosclerotic plaque stabilization. Arterioscler Thromb Vasc Biol 2009; 29: 128-33.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 128-133
    • Peeters, W.1    Hellings, W.E.2    de Kleijn, D.P.3
  • 54
    • 67650093999 scopus 로고    scopus 로고
    • Myostatin and follistatin polymorphisms interact with muscle phenotypes and ethnicity
    • Kostek MA, Angelopoulos TJ, Clarkson PM et al. Myostatin and follistatin polymorphisms interact with muscle phenotypes and ethnicity. Med Sci Sports Exerc 2009; 41: 1063-71.
    • (2009) Med Sci Sports Exerc , vol.41 , pp. 1063-1071
    • Kostek, M.A.1    Angelopoulos, T.J.2    Clarkson, P.M.3
  • 55
  • 56
    • 84884572414 scopus 로고    scopus 로고
    • Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events
    • Ijas P, Saksi J, Soinne L et al. Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events. Atherosclerosis 2013; 230: 228-34.
    • (2013) Atherosclerosis , vol.230 , pp. 228-234
    • Ijas, P.1    Saksi, J.2    Soinne, L.3
  • 57
    • 84969419791 scopus 로고    scopus 로고
    • Biomarker discovery in serum from patients with carotid atherosclerosis
    • Degraba TJ, Hoehn GT, Nyquist PA et al. Biomarker discovery in serum from patients with carotid atherosclerosis. Cerebrovasc Dis Extra 2011; 1: 115-29.
    • (2011) Cerebrovasc Dis Extra , vol.1 , pp. 115-129
    • Degraba, T.J.1    Hoehn, G.T.2    Nyquist, P.A.3
  • 58
    • 64949177776 scopus 로고    scopus 로고
    • Correlation of peripheral-blood gene expression with the extent of coronary artery stenosis
    • Wingrove JA, Daniels SE, Sehnert AJ et al. Correlation of peripheral-blood gene expression with the extent of coronary artery stenosis. Circ Cardiovasc Genet 2008; 1: 31-8.
    • (2008) Circ Cardiovasc Genet , vol.1 , pp. 31-38
    • Wingrove, J.A.1    Daniels, S.E.2    Sehnert, A.J.3
  • 59
    • 84870619337 scopus 로고    scopus 로고
    • Effects of interleukin-1beta inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: a phase IIb randomized, placebo-controlled trial
    • Ridker PM, Howard CP, Walter V et al. Effects of interleukin-1beta inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: a phase IIb randomized, placebo-controlled trial. Circulation 2012; 126: 2739-48.
    • (2012) Circulation , vol.126 , pp. 2739-2748
    • Ridker, P.M.1    Howard, C.P.2    Walter, V.3
  • 60
    • 0035846319 scopus 로고    scopus 로고
    • Prognosis after transient monocular blindness associated with carotid-artery stenosis
    • Benavente O, Eliasziw M, Streifler JY, Fox AJ, Barnett HJ, Meldrum H; North American Symptomatic Carotid Endarterectomy Trial C. Prognosis after transient monocular blindness associated with carotid-artery stenosis. N Engl J Med 2001; 345: 1084-90.
    • (2001) N Engl J Med , vol.345 , pp. 1084-1090
    • Benavente, O.1    Eliasziw, M.2    Streifler, J.Y.3    Fox, A.J.4    Barnett, H.J.5    Meldrum, H.6
  • 61
    • 0032865511 scopus 로고    scopus 로고
    • Angiogenesis and the atherosclerotic carotid plaque: an association between symptomatology and plaque morphology
    • McCarthy MJ, Loftus IM, Thompson MM et al. Angiogenesis and the atherosclerotic carotid plaque: an association between symptomatology and plaque morphology. J Vasc Surg 1999; 30: 261-8.
    • (1999) J Vasc Surg , vol.30 , pp. 261-268
    • McCarthy, M.J.1    Loftus, I.M.2    Thompson, M.M.3
  • 62
    • 27144501822 scopus 로고    scopus 로고
    • The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure
    • Freson K, De Vos R, Wittevrongel C et al. The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure. Blood 2005; 106: 2356-62.
    • (2005) Blood , vol.106 , pp. 2356-2362
    • Freson, K.1    De Vos, R.2    Wittevrongel, C.3
  • 63
    • 84876286561 scopus 로고    scopus 로고
    • Histological features of carotid plaque in patients with ocular ischemia versus cerebral events
    • Howard DP, van Lammeren GW, Redgrave JN et al. Histological features of carotid plaque in patients with ocular ischemia versus cerebral events. Stroke 2013; 44: 734-9.
    • (2013) Stroke , vol.44 , pp. 734-739
    • Howard, D.P.1    van Lammeren, G.W.2    Redgrave, J.N.3
  • 64
    • 0042024902 scopus 로고    scopus 로고
    • Prediction of cell type-specific gene modules: identification and initial characterization of a core set of smooth muscle-specific genes
    • Nelander S, Mostad P, Lindahl P. Prediction of cell type-specific gene modules: identification and initial characterization of a core set of smooth muscle-specific genes. Genome Res 2003; 13: 1838-54.
    • (2003) Genome Res , vol.13 , pp. 1838-1854
    • Nelander, S.1    Mostad, P.2    Lindahl, P.3
  • 65
    • 84856078064 scopus 로고    scopus 로고
    • Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells
    • Nanda V, Miano JM. Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells. J Biol Chem 2012; 287: 2459-67.
    • (2012) J Biol Chem , vol.287 , pp. 2459-2467
    • Nanda, V.1    Miano, J.M.2
  • 66
    • 58149134377 scopus 로고    scopus 로고
    • In vitro characterization of native mammalian smooth-muscle protein synaptopodin 2
    • Schroeter MM, Beall B, Heid HW, Chalovich JM. In vitro characterization of native mammalian smooth-muscle protein synaptopodin 2. Biosci Rep 2008; 28: 195-203.
    • (2008) Biosci Rep , vol.28 , pp. 195-203
    • Schroeter, M.M.1    Beall, B.2    Heid, H.W.3    Chalovich, J.M.4
  • 68
    • 0033671833 scopus 로고    scopus 로고
    • Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice
    • Martinez-Botas J, Anderson JB, Tessier D et al. Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice. Nat Genet 2000; 26: 474-9.
    • (2000) Nat Genet , vol.26 , pp. 474-479
    • Martinez-Botas, J.1    Anderson, J.B.2    Tessier, D.3
  • 69
    • 14344268795 scopus 로고    scopus 로고
    • Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity
    • Tansey JT, Sztalryd C, Gruia-Gray J et al. Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity. Proc Natl Acad Sci USA 2001; 98: 6494-9.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6494-6499
    • Tansey, J.T.1    Sztalryd, C.2    Gruia-Gray, J.3
  • 70
    • 18244410387 scopus 로고    scopus 로고
    • A critical appraisal of the performance, reporting, and interpretation of studies comparing carotid plaque imaging with histology
    • Lovett JK, Redgrave JN, Rothwell PM. A critical appraisal of the performance, reporting, and interpretation of studies comparing carotid plaque imaging with histology. Stroke 2005; 36: 1091-7.
    • (2005) Stroke , vol.36 , pp. 1091-1097
    • Lovett, J.K.1    Redgrave, J.N.2    Rothwell, P.M.3
  • 71
    • 82955232396 scopus 로고    scopus 로고
    • Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL
    • Turpeinen H, Raitoharju E, Oksanen A et al. Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL. Atherosclerosis 2011; 219: 799-806.
    • (2011) Atherosclerosis , vol.219 , pp. 799-806
    • Turpeinen, H.1    Raitoharju, E.2    Oksanen, A.3


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