ADAR1 is essential for intestinal homeostasis and stem cell maintenance

Cell Death and Disease

Volumn 4, Issue 4, 2013, Pages

  Qiu, W ^a   Wang, X ^a   Buchanan, M ^a   He, K ^a   Sharma, R ^a   Zhang, L ^a   Wang, Q ^a   Yu, J ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

ADAR1; Apoptosis; ER stress; Interferon signaling; Intestinal stem cell; RNA editing

Indexed keywords

ADENOSINE DEAMINASE ACTING ON RNA 1; DOUBLE STRANDED RNA; INTERFERON; UNCLASSIFIED DRUG; ADENOSINE DEAMINASE; CYTOKINE; WNT PROTEIN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; DSRNA ADENOSINE DEAMINASE; G PROTEIN COUPLED RECEPTOR; LGR5 PROTEIN, MOUSE; TAMOXIFEN;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL LINEAGE; CELL SURVIVAL; COLON; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENTERITIS; EPITHELIUM CELL; GENE DELETION; GENE LOSS; HOMEOSTASIS; INTESTINE CELL; MOUSE; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA EDITING; SIGNAL TRANSDUCTION; SMALL INTESTINE; STEM CELL; STEM CELL EXPANSION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CRYPT CELL; HEMATOPOIETIC STEM CELL; INTESTINE; INTESTINE EPITHELIUM CELL; INTESTINE INJURY; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENETICS; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM;

MUS;

ADENOSINE DEAMINASE; ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; APOPTOSIS; CELL DIFFERENTIATION; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; INFLAMMATION; INTERFERONS; INTESTINES; MICE; MICE, KNOCKOUT; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; STEM CELLS; TAMOXIFEN; WNT PROTEINS;

EID: 84879720589     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.125     Document Type: Article

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