메뉴 건너뛰기




Volumn 143, Issue 5, 1998, Pages 1341-1352

Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation

Author keywords

Apoptosis; Differentiation; Endothelium; FGF 2; Spheroid; VEGF

Indexed keywords

CD34 ANTIGEN; CYTOCHALASIN D; DNA FRAGMENT; FIBROBLAST GROWTH FACTOR; INTEGRIN; VASCULOTROPIN;

EID: 0032583125     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.143.5.1341     Document Type: Article
Times cited : (482)

References (57)
  • 1
    • 0028803509 scopus 로고
    • Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity
    • Alon, T., I. Homo, A. Itin, J. Pe'er, J. Stone, and E. Keshet. 1995. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat. Med. 1:1024-1028.
    • (1995) Nat. Med. , vol.1 , pp. 1024-1028
    • Alon, T.1    Homo, I.2    Itin, A.3    Pe'er, J.4    Stone, J.5    Keshet, E.6
  • 3
    • 0028827625 scopus 로고
    • Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
    • Asahara, T., C. Bauters, L.P. Zheng, S. Takeshita, S. Bunting, N. Ferrara, J.F. Symes, and J.M. Isner. 1995. Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo. Circulation. 92:II365-II371.
    • (1995) Circulation , vol.92
    • Asahara, T.1    Bauters, C.2    Zheng, L.P.3    Takeshita, S.4    Bunting, S.5    Ferrara, N.6    Symes, J.F.7    Isner, J.M.8
  • 5
    • 0027385553 scopus 로고
    • Senescence of aortic endothelial cells in culture: Effects of basic fibroblast growth factor expression on cell phenotype, migration, and proliferation
    • Augustin, H.G., A.K. Voss, and B.U. Pauli. 1993. Senescence of aortic endothelial cells in culture: effects of basic fibroblast growth factor expression on cell phenotype, migration, and proliferation. J. Cell. Physiol. 157: 279-288.
    • (1993) J. Cell. Physiol. , vol.157 , pp. 279-288
    • Augustin, H.G.1    Voss, A.K.2    Pauli, B.U.3
  • 6
    • 0028674873 scopus 로고
    • Differentiation of endothelial cells: Analysis of the constitutive and activated endothelial cell phenotypes
    • Augustin, H.G., D.H. Kozian, and R.C. Johnson. 1994. Differentiation of endothelial cells: analysis of the constitutive and activated endothelial cell phenotypes. Bioessays. 16:901-906.
    • (1994) Bioessays , vol.16 , pp. 901-906
    • Augustin, H.G.1    Kozian, D.H.2    Johnson, R.C.3
  • 9
    • 0028090688 scopus 로고
    • Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin
    • Baumhueter, S., N. Dybdal, C. Kyle, and L.A. Lasky. 1994. Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin. Blood. 84:2554-2565.
    • (1994) Blood , vol.84 , pp. 2554-2565
    • Baumhueter, S.1    Dybdal, N.2    Kyle, C.3    Lasky, L.A.4
  • 11
    • 0030806273 scopus 로고    scopus 로고
    • Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
    • Benjamin, L.E., and E. Keshet. 1997. Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal. Proc: Nutl. Acad. Sci. USA. 94:8761-8766.
    • (1997) Proc: Nutl. Acad. Sci. USA , vol.94 , pp. 8761-8766
    • Benjamin, L.E.1    Keshet, E.2
  • 12
    • 0031834239 scopus 로고    scopus 로고
    • A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin, L., I. Hemo, and E. Keshet. 1998. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development. 125:1591-1598.
    • (1998) Development , vol.125 , pp. 1591-1598
    • Benjamin, L.1    Hemo, I.2    Keshet, E.3
  • 20
    • 0030855630 scopus 로고    scopus 로고
    • Heterogeneity of endothelial cells. Specific markers
    • Garlanda, C., and E. Dejana. 1997. Heterogeneity of endothelial cells. Specific markers. Arterioscler. Thromb. Vasc. Biol. 17:1193-1202.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 1193-1202
    • Garlanda, C.1    Dejana, E.2
  • 21
    • 0015951363 scopus 로고
    • Human vascular endothelial cells in culture. Growth and DNA synthesis
    • Gimbrone, M.A., R.S. Cotran, and J. Folkman. 1974. Human vascular endothelial cells in culture. Growth and DNA synthesis. J. Cell Biol. 60: 673-684.
    • (1974) J. Cell Biol. , vol.60 , pp. 673-684
    • Gimbrone, M.A.1    Cotran, R.S.2    Folkman, J.3
  • 22
    • 0027133163 scopus 로고
    • Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels
    • Goto, F., K. Goto, K. Weindel, and J. Folkman. 1993. Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels. Lab. Invest. 69:508-517.
    • (1993) Lab. Invest. , vol.69 , pp. 508-517
    • Goto, F.1    Goto, K.2    Weindel, K.3    Folkman, J.4
  • 23
    • 0023256504 scopus 로고
    • Heterogeneity of mouse vascular endothelium. in vitro studies of lymphatic, large blood vessel and microvascular endothelial cells
    • Gumkowski, F., G. Kaminska, M. Kaminski, L.W. Morrissey, and R. Auerbach. 1987. Heterogeneity of mouse vascular endothelium. In vitro studies of lymphatic, large blood vessel and microvascular endothelial cells. Blood Vessels. 24:11-23.
    • (1987) Blood Vessels , vol.24 , pp. 11-23
    • Gumkowski, F.1    Kaminska, G.2    Kaminski, M.3    Morrissey, L.W.4    Auerbach, R.5
  • 24
    • 0024439457 scopus 로고
    • How does extracellular-matrix control capillary morphogenesis
    • Ingber, D.E., and J. Folkman. 1989. How does extracellular-matrix control capillary morphogenesis. Cell. 58:803-805.
    • (1989) Cell , vol.58 , pp. 803-805
    • Ingber, D.E.1    Folkman, J.2
  • 25
    • 0029005319 scopus 로고
    • Enhanced expression of CD34 messenger RNA by developing endothelial cells of mice
    • Ito, A., S. Nomura, S. Hirota, T. Suda, and Y. Kitamura. 1995. Enhanced expression of CD34 messenger RNA by developing endothelial cells of mice. Lab. Invest. 72:532-538.
    • (1995) Lab. Invest. , vol.72 , pp. 532-538
    • Ito, A.1    Nomura, S.2    Hirota, S.3    Suda, T.4    Kitamura, Y.5
  • 26
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
    • Jaffe, E.A., R.L. Nachman, C.G. Becker, and C.R. Minick, 1973. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52:2745-2756.
    • (1973) J. Clin. Invest. , vol.52 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 27
    • 0030696785 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms
    • Karsan, A., E. Yee, G.G. Poirier, P. Zhou, R. Craig, J.M. Harlan, 1997. Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms. Am. J. Pathol. 151:1775-1784.
    • (1997) Am. J. Pathol. , vol.151 , pp. 1775-1784
    • Karsan, A.1    Yee, E.2    Poirier, G.G.3    Zhou, P.4    Craig, R.5    Harlan, J.M.6
  • 28
    • 0028880305 scopus 로고
    • Expression of the vascular endothelial growth factor (VEGF) receptor gene KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation
    • Katoh, O., H. Tauchi, K. Kawaishi, A. Kimura, and Y. Satow. 1995. Expression of the vascular endothelial growth factor (VEGF) receptor gene KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation. Cancer Res. 55:5687-5692.
    • (1995) Cancer Res. , vol.55 , pp. 5687-5692
    • Katoh, O.1    Tauchi, H.2    Kawaishi, K.3    Kimura, A.4    Satow, Y.5
  • 29
    • 0028841640 scopus 로고
    • In vitro differentiation of embryonic stem cells
    • Keller, G.M. 1995. In vitro differentiation of embryonic stem cells. Curr. Opin. Cell Biol. 7:862-869.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 862-869
    • Keller, G.M.1
  • 30
    • 0000593022 scopus 로고    scopus 로고
    • Interendothelial junctions: Structure, signalling and functional roles
    • Lampugnani, M.G., and E. Dejana. 1997. Interendothelial junctions: structure, signalling and functional roles. Curr. Opin. Cell Biol. 9:674-682.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 674-682
    • Lampugnani, M.G.1    Dejana, E.2
  • 31
    • 0030701901 scopus 로고    scopus 로고
    • Formation of spheroid structures in a human colon carcinoma cell line involves a complex series of intercellular rearrangements
    • Lincz, L.F., A. Buret, and G.F. Burns. 1997. Formation of spheroid structures in a human colon carcinoma cell line involves a complex series of intercellular rearrangements. Differentiation. 61:261-274.
    • (1997) Differentiation , vol.61 , pp. 261-274
    • Lincz, L.F.1    Buret, A.2    Burns, G.F.3
  • 33
    • 0030848490 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-induced in vitro angiogenesis and plasminogen activator expression are dependent on endogenous basic fibroblast growth factor
    • Mandriota, S.J., and M.S. Pepper. 1997. Vascular endothelial growth factor-induced in vitro angiogenesis and plasminogen activator expression are dependent on endogenous basic fibroblast growth factor. J. Cell Sci. 110:2293-2302.
    • (1997) J. Cell Sci. , vol.110 , pp. 2293-2302
    • Mandriota, S.J.1    Pepper, M.S.2
  • 35
    • 0026351399 scopus 로고
    • Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner
    • Mignatti, P., T. Morimoto, and D.B. Rifkin. 1991. Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner. Proc. Natl. Acad. Sci. USA. 88:11007-11011.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 11007-11011
    • Mignatti, P.1    Morimoto, T.2    Rifkin, D.B.3
  • 36
    • 0030697292 scopus 로고    scopus 로고
    • Three-dimensional cell cultures: From molecular mechanisms to clinical applications
    • Müller-Klieser, W. 1997. Three-dimensional cell cultures: from molecular mechanisms to clinical applications. Am. J. Physiol. 273:C1109-C1123.
    • (1997) Am. J. Physiol. , vol.273
    • Müller-Klieser, W.1
  • 38
    • 0027053487 scopus 로고
    • Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
    • Pepper, M.S., N. Ferrara, L. Orci, and R. Montesano. 1992. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys. Res. Commun. 189:824-831.
    • (1992) Biochem Biophys. Res. Commun. , vol.189 , pp. 824-831
    • Pepper, M.S.1    Ferrara, N.2    Orci, L.3    Montesano, R.4
  • 39
    • 0029095492 scopus 로고
    • Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules
    • Puri, K.D., E.B. Finger, G. Gaudernack, and T.A. Springer. 1995. Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules. J. Cell Biol. 131:261-270.
    • (1995) J. Cell Biol. , vol.131 , pp. 261-270
    • Puri, K.D.1    Finger, E.B.2    Gaudernack, G.3    Springer, T.A.4
  • 40
    • 0028072225 scopus 로고
    • Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells
    • Re, F., A. Zanetti, M. Sironi, N. Polentarutti, L. Lanfrancone, E. Dejana, and F. Colotta. 1994. Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells. J. Cell Biol. 127: 537-546.
    • (1994) J. Cell Biol. , vol.127 , pp. 537-546
    • Re, F.1    Zanetti, A.2    Sironi, M.3    Polentarutti, N.4    Lanfrancone, L.5    Dejana, E.6    Colotta, F.7
  • 41
    • 0029112837 scopus 로고
    • Differentiation of endothelium
    • Risau, W. 1995. Differentiation of endothelium. FASEB J. 9:923-933.
    • (1995) FASEB J. , vol.9 , pp. 923-933
    • Risau, W.1
  • 42
    • 0028335948 scopus 로고
    • Anchorage dependence, integrins, and apoptosis
    • Ruoslahti, E., and J.C. Reed. 1994. Anchorage dependence, integrins, and apoptosis. Cell. 77:477-478.
    • (1994) Cell , vol.77 , pp. 477-478
    • Ruoslahti, E.1    Reed, J.C.2
  • 43
    • 0032571115 scopus 로고    scopus 로고
    • Angiogenic stimuli are essential for survival of vascular endothelial cells in three-dimensional collagen lattice
    • Satake, S., M. Kuzuya, M.A. Ramos, S. Kanda, and A. Iguchi. 1998. Angiogenic stimuli are essential for survival of vascular endothelial cells in three-dimensional collagen lattice. Biochem. Biophys. Res. Commun. 244:642-646.
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 642-646
    • Satake, S.1    Kuzuya, M.2    Ramos, M.A.3    Kanda, S.4    Iguchi, A.5
  • 44
    • 0030661566 scopus 로고    scopus 로고
    • Integrins, oncogenes, and anchorage independence
    • Schwartz, M.A. 1997. Integrins, oncogenes, and anchorage independence. J. Cell Biol. 139:575-578.
    • (1997) J. Cell Biol. , vol.139 , pp. 575-578
    • Schwartz, M.A.1
  • 45
    • 0018240273 scopus 로고
    • Selection and characterization of bovine aortic endothelial cells
    • Schwartz, S.M. 1978. Selection and characterization of bovine aortic endothelial cells. In Vitro. 14:966-980.
    • (1978) In Vitro , vol.14 , pp. 966-980
    • Schwartz, S.M.1
  • 46
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki, D., A. Itin, D. Soffer, and E. Keshet. 1992. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 359:843-845.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 47
    • 0031149457 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits endothelial cell apoptosis induced by tumor necrosis factor-α: Balance between growth and death signals
    • Spyridopoulos, I., E. Brogi, M. Kearney, A.B. Sullivan, C. Cetrulo, J.M. Isner, and D.W. Losordo. 1997. Vascular endothelial growth factor inhibits endothelial cell apoptosis induced by tumor necrosis factor-α: balance between growth and death signals. J. Mol. Cell Cardiol. 29:1321-1330.
    • (1997) J. Mol. Cell Cardiol. , vol.29 , pp. 1321-1330
    • Spyridopoulos, I.1    Brogi, E.2    Kearney, M.3    Sullivan, A.B.4    Cetrulo, C.5    Isner, J.M.6    Losordo, D.W.7
  • 48
    • 0029072011 scopus 로고
    • Basic fibroblast growth factor upregulates the expression of vascular endothelial growth factor in vascular smooth muscle cells: Synergistic interaction with hypoxia
    • Stavri, G.T., I.C. Zachary, P.A. Baskerville, J.F. Martin, and J.D. Erusalimsky. 1995. Basic fibroblast growth factor upregulates the expression of vascular endothelial growth factor in vascular smooth muscle cells: synergistic interaction with hypoxia. Circulation. 92:11-14.
    • (1995) Circulation , vol.92 , pp. 11-14
    • Stavri, G.T.1    Zachary, I.C.2    Baskerville, P.A.3    Martin, J.F.4    Erusalimsky, J.D.5
  • 49
    • 0024281372 scopus 로고
    • Cell and environment interactions in tumor microregions: The multicell spheroid model
    • Sutherland, R.M. 1988. Cell and environment interactions in tumor microregions: the multicell spheroid model. Science. 240:177-184.
    • (1988) Science , vol.240 , pp. 177-184
    • Sutherland, R.M.1
  • 50
    • 84907113049 scopus 로고
    • Review: The integrin αVβ3: angiogenesis and apoptosis
    • Varner, J.A., P.C. Brooks, and D.A. Cheresh. 1995. Review: the integrin αVβ3: angiogenesis and apoptosis. Cell Adhes. Commun. 3:367-374.
    • (1995) Cell Adhes. Commun. , vol.3 , pp. 367-374
    • Varner, J.A.1    Brooks, P.C.2    Cheresh, D.A.3
  • 51
    • 0027762048 scopus 로고
    • Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury
    • Villaschi, S., and R.F. Nicosia. 1993. Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury. Am. J. Pathol. 143:181-190.
    • (1993) Am. J. Pathol. , vol.143 , pp. 181-190
    • Villaschi, S.1    Nicosia, R.F.2
  • 52
    • 0029998039 scopus 로고    scopus 로고
    • Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps
    • Vittet, D., M.H. Prandini, R. Berthier, A. Schweitzer, H. Martin-Sisteron, G. Uzan, and E. Dejana. 1996. Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps. Blood. 88:3424-3431.
    • (1996) Blood , vol.88 , pp. 3424-3431
    • Vittet, D.1    Prandini, M.H.2    Berthier, R.3    Schweitzer, A.4    Martin-Sisteron, H.5    Uzan, G.6    Dejana, E.7
  • 53
    • 0031570726 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor inhibits anchorage-disruption-induced apoptosis in microvessel endothelial cells by inducing scaffold formation
    • Watanabe, Y., and H.F. Dvorak. 1997. Vascular permeability factor/vascular endothelial growth factor inhibits anchorage-disruption-induced apoptosis in microvessel endothelial cells by inducing scaffold formation. Exp. Cell Res. 233:340-349.
    • (1997) Exp. Cell Res. , vol.233 , pp. 340-349
    • Watanabe, Y.1    Dvorak, H.F.2
  • 54
    • 0028246186 scopus 로고
    • Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes
    • Wolburg, H., J. Neuhaus, U. Kniesel, B. Krauss, E.M. Schmid, M. Ocalan, C. Farrell, and W. Risau. 1994. Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes. J. Cell Sci. 107:1347-1357.
    • (1994) J. Cell Sci. , vol.107 , pp. 1347-1357
    • Wolburg, H.1    Neuhaus, J.2    Kniesel, U.3    Krauss, B.4    Schmid, E.M.5    Ocalan, M.6    Farrell, C.7    Risau, W.8
  • 55
    • 0027336995 scopus 로고
    • flk-1, and flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors
    • Yamaguchi, T.P., D.J. Dumont, R.A. Conlon, M.L. Breitman, and J. Rossant. 1993. flk-1, and flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development. 118:489-498.
    • (1993) Development , vol.118 , pp. 489-498
    • Yamaguchi, T.P.1    Dumont, D.J.2    Conlon, R.A.3    Breitman, M.L.4    Rossant, J.5
  • 56
    • 0025053948 scopus 로고
    • Autocrine regulation of cell growth and transformation by basic fibroblast growth factor
    • Yayon, A., and M. Klagsbrun. 1990. Autocrine regulation of cell growth and transformation by basic fibroblast growth factor. Cancer Metastasis Rev. 9:191-202.
    • (1990) Cancer Metastasis Rev. , vol.9 , pp. 191-202
    • Yayon, A.1    Klagsbrun, M.2
  • 57
    • 0028813674 scopus 로고
    • The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development
    • Young, P.E., S. Baumhueter, and L.A. Lasky. 1995. The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development. Blood. 85:96-105.
    • (1995) Blood , vol.85 , pp. 96-105
    • Young, P.E.1    Baumhueter, S.2    Lasky, L.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.