The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

Cell Reports

Volumn 9, Issue 4, 2014, Pages 1482-1494

  Mannion, Niamh M ^a   Greenwood, Sam M ^a   Young, Robert ^a   Cox, Sarah ^a   Brindle, James ^a   Read, David ^a   Nellåker, Christoffer ^b   Vesely, Cornelia ^c   Ponting, Chris P ^b   McLaughlin, Paul J ^d   Jantsch, Michael F ^c   Dorin, Julia ^a   Adams, Ian R ^a   Scadden, A D J ^e   Öhman, Marie ^f   Keegan, Liam P ^a   O'Connell, Mary A ^a,f  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF VIENNA   (Austria)

^d School of Biological Sciences   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADAR1 PROTEIN; ALPHA INTERFERON A; DOUBLE STRANDED RNA; INOSINE; INTERLEUKIN 1; INTERLEUKIN 6; RNA BINDING PROTEIN; STAT1 PROTEIN; UNCLASSIFIED DRUG; ADAR1 PROTEIN, HUMAN; ADAR1 PROTEIN, MOUSE; ADENOSINE DEAMINASE; AUTACOID; CYTOKINE; INTERFERON RECEPTOR; IPS-1 PROTEIN, MOUSE; PROTEIN P53; SIGNAL TRANSDUCING ADAPTOR PROTEIN; URACIL;

ADAR1 GENE; AICARDI GOUTIERES SYNDROME; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; EMBRYO; EMBRYO DEATH; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; INNATE IMMUNITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN INTERACTION; RNA CLEAVAGE; RNA EDITING; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANIMAL EMBRYO; C57BL MOUSE; CROSS BREEDING; FEMALE; FIBROBLAST; GENETICS; HUMAN; IMMUNOLOGY; LIVER; MALE; METABOLISM; MUTATION; NERVOUS SYSTEM MALFORMATION; NEUROLOGIC DISEASE; PATHOLOGY; PHENOTYPE; SURVIVAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE DEAMINASE; ANIMALS; AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM; CROSSES, GENETIC; CYTOKINES; EMBRYO LOSS; EMBRYO, MAMMALIAN; FEMALE; FIBROBLASTS; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; INOSINE; LIVER; MALE; MICE, INBRED C57BL; MUTATION; NERVOUS SYSTEM MALFORMATIONS; PHENOTYPE; RECEPTORS, INTERFERON; RNA EDITING; RNA, DOUBLE-STRANDED; RNA-BINDING PROTEINS; SURVIVAL ANALYSIS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; URACIL;

EID: 84912098781     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.10.041     Document Type: Article

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