-
1
-
-
0033118334
-
Molecular tinkering of G protein-coupled receptros: an evolutionary success
-
Bockaert J and Pin JP (1999) Molecular tinkering of G protein-coupled receptros: an evolutionary success. EMBO J 18, 1723–1729.
-
(1999)
EMBO J
, vol.18
, pp. 1723-1729
-
-
Bockaert, J.1
Pin, J.P.2
-
2
-
-
84870702282
-
Structure-function studies with G protein-coupled receptors as a paradigm for improving drug discovery and development of therapeutics
-
McNeely PM, Naranjo AN and Robinson AS (2012) Structure-function studies with G protein-coupled receptors as a paradigm for improving drug discovery and development of therapeutics. Biotechnol J 7, 1451–1461.
-
(2012)
Biotechnol J
, vol.7
, pp. 1451-1461
-
-
McNeely, P.M.1
Naranjo, A.N.2
Robinson, A.S.3
-
3
-
-
0036780743
-
G-protein-coupled receptor oligomerization and its potential for drug discovery
-
George SR, O'Dowd BF and Lee SP (2002) G-protein-coupled receptor oligomerization and its potential for drug discovery. Nat Rev Drug Discov 1, 808–820.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 808-820
-
-
George, S.R.1
O'Dowd, B.F.2
Lee, S.P.3
-
5
-
-
2642550862
-
Challenges in the development of high protein concentration formulations
-
Shire SJ, Shahrokh Z and Liu J (2004) Challenges in the development of high protein concentration formulations. J Pharm Sci 93, 1390–1402.
-
(2004)
J Pharm Sci
, vol.93
, pp. 1390-1402
-
-
Shire, S.J.1
Shahrokh, Z.2
Liu, J.3
-
6
-
-
78349305715
-
Dynamics and flexibility of G-protein-coupled receptor conformations and their relevance to drug design
-
Vaidehi N (2010) Dynamics and flexibility of G-protein-coupled receptor conformations and their relevance to drug design. Drug Discov Today 15, 951–957.
-
(2010)
Drug Discov Today
, vol.15
, pp. 951-957
-
-
Vaidehi, N.1
-
7
-
-
51949088673
-
Lipid-rhodopsin hydrophobic mismatch alters rhodopsin helical content
-
Soubias O, Niu S, Mitchell DC and Gawrisch K (2008) Lipid-rhodopsin hydrophobic mismatch alters rhodopsin helical content. J Am Chem Soc 130, 12465–12471.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 12465-12471
-
-
Soubias, O.1
Niu, S.2
Mitchell, D.C.3
Gawrisch, K.4
-
8
-
-
78751683949
-
The morphology and composition of cholesterol-rich micellar nanostructures determine transmembrane protein (GPCR) activity
-
O'Malley MA, Helgeson ME, Wagner NJ and Robinson AS (2011) The morphology and composition of cholesterol-rich micellar nanostructures determine transmembrane protein (GPCR) activity. Biophys J 100, L11–L13.
-
(2011)
Biophys J
, vol.100
, pp. L11-L13
-
-
O'Malley, M.A.1
Helgeson, M.E.2
Wagner, N.J.3
Robinson, A.S.4
-
9
-
-
84926623484
-
Large-scale production and protein engineering of G protein-coupled receptors for structural studies
-
Milic D and Veprintsev DB (2015) Large-scale production and protein engineering of G protein-coupled receptors for structural studies. Front Pharmacol 6, 66.
-
(2015)
Front Pharmacol
, vol.6
, pp. 66
-
-
Milic, D.1
Veprintsev, D.B.2
-
10
-
-
33645415883
-
Exceptional total and functional yields of the human adenosine (A2a) receptor expressed in the yeast Saccharomyces cerevisiae
-
Niebauer RT and Robinson AS (2006) Exceptional total and functional yields of the human adenosine (A2a) receptor expressed in the yeast Saccharomyces cerevisiae. Protein Expr Purif 46, 204–211.
-
(2006)
Protein Expr Purif
, vol.46
, pp. 204-211
-
-
Niebauer, R.T.1
Robinson, A.S.2
-
11
-
-
34250350252
-
High-level expression in Saccharomyces cerevisiae enables isolation and spectroscopic characterization of functional human adenosine A2a receptor
-
O'Malley MA, Lazarova T, Britton ZT and Robinson AS (2007) High-level expression in Saccharomyces cerevisiae enables isolation and spectroscopic characterization of functional human adenosine A2a receptor. J Struct Biol 159, 166–178.
-
(2007)
J Struct Biol
, vol.159
, pp. 166-178
-
-
O'Malley, M.A.1
Lazarova, T.2
Britton, Z.T.3
Robinson, A.S.4
-
12
-
-
33749987003
-
Optimization of the human adenosine A2a receptor yields in Saccharomyces cerevisiae
-
Wedekind A, O'Malley MA, Niebauer RT and Robinson AS (2006) Optimization of the human adenosine A2a receptor yields in Saccharomyces cerevisiae. Biotechnol Prog 22, 1249–1255.
-
(2006)
Biotechnol Prog
, vol.22
, pp. 1249-1255
-
-
Wedekind, A.1
O'Malley, M.A.2
Niebauer, R.T.3
Robinson, A.S.4
-
13
-
-
0942265965
-
Homodimerization of adenosine A2a receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer
-
Canals M, Burgueno J, Marcellino D, Cabello N, Canela EI, Mallol J, Agnati LF, Ferre S, Bouvier M, Fuxe K et al. (2004) Homodimerization of adenosine A2a receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. J Neurochem 88, 726–734.
-
(2004)
J Neurochem
, vol.88
, pp. 726-734
-
-
Canals, M.1
Burgueno, J.2
Marcellino, D.3
Cabello, N.4
Canela, E.I.5
Mallol, J.6
Agnati, L.F.7
Ferre, S.8
Bouvier, M.9
Fuxe, K.10
-
14
-
-
79960181417
-
Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine
-
Dore AS, Robertson N, Errey JC, Ng I, Hollenstein K, Tehan B, Hurrell E, Bennett K, Congreve M, Magnani F et al. (2011) Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine. Structure 19, 1283–1293.
-
(2011)
Structure
, vol.19
, pp. 1283-1293
-
-
Dore, A.S.1
Robertson, N.2
Errey, J.C.3
Ng, I.4
Hollenstein, K.5
Tehan, B.6
Hurrell, E.7
Bennett, K.8
Congreve, M.9
Magnani, F.10
-
15
-
-
84862776818
-
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
-
Hino T, Arakawa T, Iwanari H, Yurugi-Kobayashi T, Ikeda-Suno C, Nakada-Nakura Y, Kusano-Arai O, Weyand S, Shimamura T, Nomura N et al. (2012) G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody. Nature 482, 237–240.
-
(2012)
Nature
, vol.482
, pp. 237-240
-
-
Hino, T.1
Arakawa, T.2
Iwanari, H.3
Yurugi-Kobayashi, T.4
Ikeda-Suno, C.5
Nakada-Nakura, Y.6
Kusano-Arai, O.7
Weyand, S.8
Shimamura, T.9
Nomura, N.10
-
16
-
-
56749103466
-
The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist
-
Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP and Stevens RC (2008) The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science 322, 1211–1217.
-
(2008)
Science
, vol.322
, pp. 1211-1217
-
-
Jaakola, V.P.1
Griffith, M.T.2
Hanson, M.A.3
Cherezov, V.4
Chien, E.Y.5
Lane, J.R.6
Ijzerman, A.P.7
Stevens, R.C.8
-
17
-
-
84935522404
-
Molecular determinants of CGS21680 binding to the human adenosine A2A receptor
-
Lebon G, Edwards PC, Leslie AG and Tate CG (2015) Molecular determinants of CGS21680 binding to the human adenosine A2A receptor. Mol Pharmacol 87, 907–915.
-
(2015)
Mol Pharmacol
, vol.87
, pp. 907-915
-
-
Lebon, G.1
Edwards, P.C.2
Leslie, A.G.3
Tate, C.G.4
-
18
-
-
79959564813
-
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
-
Lebon G, Warne T, Edwards PC, Bennett K, Langmead CJ, Leslie AG and Tate CG (2011) Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation. Nature 474, 521–525.
-
(2011)
Nature
, vol.474
, pp. 521-525
-
-
Lebon, G.1
Warne, T.2
Edwards, P.C.3
Bennett, K.4
Langmead, C.J.5
Leslie, A.G.6
Tate, C.G.7
-
19
-
-
84861961427
-
Structural basis for allosteric regulation of GPCRs by sodium ions
-
Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, Heitman LH, AP IJ et al. (2012) Structural basis for allosteric regulation of GPCRs by sodium ions. Science 337, 232–236.
-
(2012)
Science
, vol.337
, pp. 232-236
-
-
Liu, W.1
Chun, E.2
Thompson, A.A.3
Chubukov, P.4
Xu, F.5
Katritch, V.6
Han, G.W.7
Roth, C.B.8
Heitman, L.H.9
Ap, I.10
-
20
-
-
79954782236
-
Structure of an agonist-bound human A2A adenosine receptor
-
Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V and Stevens RC (2011) Structure of an agonist-bound human A2A adenosine receptor. Science 332, 322–327.
-
(2011)
Science
, vol.332
, pp. 322-327
-
-
Xu, F.1
Wu, H.2
Katritch, V.3
Han, G.W.4
Jacobson, K.A.5
Gao, Z.G.6
Cherezov, V.7
Stevens, R.C.8
-
21
-
-
84904576722
-
G-protein-coupled receptor heteromers as key players in the molecular architecture of the central nervous system
-
Brugarolas M, Navarro G, Martinez-Pinilla E, Angelats E, Casado V, Lanciego JL and Franco R (2014) G-protein-coupled receptor heteromers as key players in the molecular architecture of the central nervous system. CNS Neurosci Ther 20, 703–709.
-
(2014)
CNS Neurosci Ther
, vol.20
, pp. 703-709
-
-
Brugarolas, M.1
Navarro, G.2
Martinez-Pinilla, E.3
Angelats, E.4
Casado, V.5
Lanciego, J.L.6
Franco, R.7
-
22
-
-
0037287572
-
Glutamate mGlu5-adenosine A2A-dopamine D2 receptor interactions in the striatum. Implications for drug therapy in neuro-psychiatric disorders and drug abuse
-
Ferre S, Ciruela F, Woods AS, Canals M, Burgueno J, Marcellino D, Karcz-Kubicha M, Hope BT, Morales M, Popoli P et al. (2003) Glutamate mGlu5-adenosine A2A-dopamine D2 receptor interactions in the striatum. Implications for drug therapy in neuro-psychiatric disorders and drug abuse. Curr Med Chem Cent Nerv Syst Agents 3, 1–26.
-
(2003)
Curr Med Chem Cent Nerv Syst Agents
, vol.3
, pp. 1-26
-
-
Ferre, S.1
Ciruela, F.2
Woods, A.S.3
Canals, M.4
Burgueno, J.5
Marcellino, D.6
Karcz-Kubicha, M.7
Hope, B.T.8
Morales, M.9
Popoli, P.10
-
23
-
-
47349126631
-
An update on adenosine A2a-dopamine D2 receptor interactions: implications for the function of G protein-coupled receptors
-
Ferre S, Quiroz C, Woods AS, Cunha R, Popoli P, Ciruela F, Lluis C, Franco R, Azdad K and Schiffmann SN (2008) An update on adenosine A2a-dopamine D2 receptor interactions: implications for the function of G protein-coupled receptors. Curr Pharm Des 14, 1468–1474.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 1468-1474
-
-
Ferre, S.1
Quiroz, C.2
Woods, A.S.3
Cunha, R.4
Popoli, P.5
Ciruela, F.6
Lluis, C.7
Franco, R.8
Azdad, K.9
Schiffmann, S.N.10
-
24
-
-
13444271067
-
Adenosine A2A receptor and dopamine D3 receptor interactions: evidence of functional A2A/D3 heteromeric complexes
-
Torvinen M, Marcellino D, Canals M, Agnati LF, Lluis C, Franco R and Fuxe K (2005) Adenosine A2A receptor and dopamine D3 receptor interactions: evidence of functional A2A/D3 heteromeric complexes. Mol Pharmacol 67, 400–407.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 400-407
-
-
Torvinen, M.1
Marcellino, D.2
Canals, M.3
Agnati, L.F.4
Lluis, C.5
Franco, R.6
Fuxe, K.7
-
25
-
-
79953171859
-
Adenosine receptor containing oligomers: their role in the control of dopamine and glutamate neurotransmission in the brain
-
Ciruela F, Gomez-Soler M, Guidolin D, Borroto-Escuela DO, Agnati LF, Fuxe K and Fernandez-Duenas V (2011) Adenosine receptor containing oligomers: their role in the control of dopamine and glutamate neurotransmission in the brain. Biochim Biophys Acta 1808, 1245–1255.
-
(2011)
Biochim Biophys Acta
, vol.1808
, pp. 1245-1255
-
-
Ciruela, F.1
Gomez-Soler, M.2
Guidolin, D.3
Borroto-Escuela, D.O.4
Agnati, L.F.5
Fuxe, K.6
Fernandez-Duenas, V.7
-
26
-
-
56649106450
-
Adenosine A(2A) receptors assemble into higher-order oligomers at the plasma membrane
-
Vidi PA, Chen J, Irudayaraj JM and Watts VJ (2008) Adenosine A(2A) receptors assemble into higher-order oligomers at the plasma membrane. FEBS Lett 582, 3985–3990.
-
(2008)
FEBS Lett
, vol.582
, pp. 3985-3990
-
-
Vidi, P.A.1
Chen, J.2
Irudayaraj, J.M.3
Watts, V.J.4
-
27
-
-
84923854268
-
The GPCR heterotetramer: challenging classical pharmacology
-
Ferre S (2015) The GPCR heterotetramer: challenging classical pharmacology. Trends Pharmacol Sci 36, 145–152.
-
(2015)
Trends Pharmacol Sci
, vol.36
, pp. 145-152
-
-
Ferre, S.1
-
28
-
-
84932112617
-
Allosteric mechanisms within the adenosine A2a-dopamine D2 receptor heterotetramer
-
Ferre S, Bonaventura J, Tomasi D, Navarro G, Moreno E, Cortes A, Lluis C, Casado V and Volkow ND (2015) Allosteric mechanisms within the adenosine A2a-dopamine D2 receptor heterotetramer. Neuropharmacology 104, 154–160.
-
(2015)
Neuropharmacology
, vol.104
, pp. 154-160
-
-
Ferre, S.1
Bonaventura, J.2
Tomasi, D.3
Navarro, G.4
Moreno, E.5
Cortes, A.6
Lluis, C.7
Casado, V.8
Volkow, N.D.9
-
29
-
-
25844477182
-
Adenosine A2a and dopamine D2 heteromeric receptor complexes and their function
-
Fuxe K, Ferre S, Canals M, Torvinen M, Terasmaa A, Marcellino D, Goldberg SR, Staines W, Jacobsen KX, Lluis C et al. (2005) Adenosine A2a and dopamine D2 heteromeric receptor complexes and their function. J Mol Neurosci 26, 209–219.
-
(2005)
J Mol Neurosci
, vol.26
, pp. 209-219
-
-
Fuxe, K.1
Ferre, S.2
Canals, M.3
Torvinen, M.4
Terasmaa, A.5
Marcellino, D.6
Goldberg, S.R.7
Staines, W.8
Jacobsen, K.X.9
Lluis, C.10
-
30
-
-
84924047517
-
Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance
-
Bocquet N, Kohler J, Hug MN, Kusznir EA, Rufer AC, Dawson RJ, Hennig M, Ruf A, Huber W and Huber S (2015) Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance. Biochim Biophys Acta 1848, 1224–1233.
-
(2015)
Biochim Biophys Acta
, vol.1848
, pp. 1224-1233
-
-
Bocquet, N.1
Kohler, J.2
Hug, M.N.3
Kusznir, E.A.4
Rufer, A.C.5
Dawson, R.J.6
Hennig, M.7
Ruf, A.8
Huber, W.9
Huber, S.10
-
31
-
-
84927919762
-
G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent
-
Jamshad M, Charlton J, Lin YP, Routledge SJ, Bawa Z, Knowles TJ, Overduin M, Dekker N, Dafforn TR, Bill RM et al. (2015) G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent. Biosci Rep 35, e00188.
-
(2015)
Biosci Rep
, vol.35
-
-
Jamshad, M.1
Charlton, J.2
Lin, Y.P.3
Routledge, S.J.4
Bawa, Z.5
Knowles, T.J.6
Overduin, M.7
Dekker, N.8
Dafforn, T.R.9
Bill, R.M.10
-
32
-
-
34250666273
-
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
-
Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B and Sunahara RK (2007) A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci USA 104, 7682–7687.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7682-7687
-
-
Whorton, M.R.1
Bokoch, M.P.2
Rasmussen, S.G.3
Huang, B.4
Zare, R.N.5
Kobilka, B.6
Sunahara, R.K.7
-
33
-
-
42949164679
-
Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer
-
Whorton MR, Jastrzebska B, Park PS, Fotiadis D, Engel A, Palczewski K and Sunahara RK (2008) Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer. J Biol Chem 283, 4387–4394.
-
(2008)
J Biol Chem
, vol.283
, pp. 4387-4394
-
-
Whorton, M.R.1
Jastrzebska, B.2
Park, P.S.3
Fotiadis, D.4
Engel, A.5
Palczewski, K.6
Sunahara, R.K.7
-
34
-
-
34547434085
-
Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit
-
Ernst OP, Gramse V, Kolbe M, Hofmann KP and Heck M (2007) Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit. Proc Natl Acad Sci USA 104, 10859–10864.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 10859-10864
-
-
Ernst, O.P.1
Gramse, V.2
Kolbe, M.3
Hofmann, K.P.4
Heck, M.5
-
35
-
-
79953194763
-
Dimerization and ligand binding affect the structure network of A(2A) adenosine receptor
-
Fanelli F and Felline A (2011) Dimerization and ligand binding affect the structure network of A(2A) adenosine receptor. Biochim Biophys Acta 1808, 1256–1266.
-
(2011)
Biochim Biophys Acta
, vol.1808
, pp. 1256-1266
-
-
Fanelli, F.1
Felline, A.2
-
36
-
-
17944383882
-
The adenosine A2a receptor interacts with the actin-binding protein alpha-actinin
-
Burgueno J, Blake DJ, Benson MA, Tinsley CL, Esapa CT, Canela EI, Penela P, Mallol J, Mayor F Jr, Lluis C et al. (2003) The adenosine A2a receptor interacts with the actin-binding protein alpha-actinin. J Biol Chem 278, 37545–37552.
-
(2003)
J Biol Chem
, vol.278
, pp. 37545-37552
-
-
Burgueno, J.1
Blake, D.J.2
Benson, M.A.3
Tinsley, C.L.4
Esapa, C.T.5
Canela, E.I.6
Penela, P.7
Mallol, J.8
Mayor, F.9
Lluis, C.10
-
37
-
-
4544278502
-
Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2a and dopamine D2 receptors
-
Ciruela F, Burgueno J, Casado V, Canals M, Marcellino D, Goldberg SR, Bader M, Fuxe K, Agnati LF, Lluis C et al. (2004) Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2a and dopamine D2 receptors. Anal Chem 76, 5354–5363.
-
(2004)
Anal Chem
, vol.76
, pp. 5354-5363
-
-
Ciruela, F.1
Burgueno, J.2
Casado, V.3
Canals, M.4
Marcellino, D.5
Goldberg, S.R.6
Bader, M.7
Fuxe, K.8
Agnati, L.F.9
Lluis, C.10
-
38
-
-
84858203893
-
Fluorescence/bioluminescence resonance energy transfer techniques to study G-protein-coupled receptor activation and signaling
-
Lohse MJ, Nuber S and Hoffmann C (2012) Fluorescence/bioluminescence resonance energy transfer techniques to study G-protein-coupled receptor activation and signaling. Pharmacol Rev 64, 299–336.
-
(2012)
Pharmacol Rev
, vol.64
, pp. 299-336
-
-
Lohse, M.J.1
Nuber, S.2
Hoffmann, C.3
-
39
-
-
84915747589
-
Kinetics of the early events of GPCR signalling
-
Adamson RJ and Watts A (2014) Kinetics of the early events of GPCR signalling. FEBS Lett 588, 4701–4707.
-
(2014)
FEBS Lett
, vol.588
, pp. 4701-4707
-
-
Adamson, R.J.1
Watts, A.2
-
40
-
-
84888364004
-
Surface plasmon resonance spectroscopy for characterisation of membrane protein-ligand interactions and its potential for drug discovery
-
Patching SG (2014) Surface plasmon resonance spectroscopy for characterisation of membrane protein-ligand interactions and its potential for drug discovery. Biochim Biophys Acta 1838, 43–55.
-
(2014)
Biochim Biophys Acta
, vol.1838
, pp. 43-55
-
-
Patching, S.G.1
-
41
-
-
44949236117
-
High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation
-
Altenbach C, Kusnetzow AK, Ernst OP, Hofmann KP and Hubbell WL (2008) High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation. Proc Natl Acad Sci USA 105, 7439–7444.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7439-7444
-
-
Altenbach, C.1
Kusnetzow, A.K.2
Ernst, O.P.3
Hofmann, K.P.4
Hubbell, W.L.5
-
42
-
-
84908512395
-
Determining the oligomeric structure of proteorhodopsin by Gd3+ – based pulsed dipolar spectroscopy of multiple distances
-
Edwards DT, Huber T, Hussain S, Stone KM, Kinnebrew M, Kaminker I, Matalon E, Sherwin MS, Goldfarb D and Han S (2014) Determining the oligomeric structure of proteorhodopsin by Gd3+ – based pulsed dipolar spectroscopy of multiple distances. Structure 22, 1677–1686.
-
(2014)
Structure
, vol.22
, pp. 1677-1686
-
-
Edwards, D.T.1
Huber, T.2
Hussain, S.3
Stone, K.M.4
Kinnebrew, M.5
Kaminker, I.6
Matalon, E.7
Sherwin, M.S.8
Goldfarb, D.9
Han, S.10
-
43
-
-
84872782969
-
Structural insight into proteorhodopsin oligomers
-
Stone KM, Voska J, Kinnebrew M, Pavlova A, Junk MJ and Han S (2013) Structural insight into proteorhodopsin oligomers. Biophys J 104, 472–481.
-
(2013)
Biophys J
, vol.104
, pp. 472-481
-
-
Stone, K.M.1
Voska, J.2
Kinnebrew, M.3
Pavlova, A.4
Junk, M.J.5
Han, S.6
-
44
-
-
79953865760
-
Molecular dynamics of proteorhodopsin in lipid bilayers by solid-state NMR
-
Yang J, Aslimovska L and Glaubitz C (2011) Molecular dynamics of proteorhodopsin in lipid bilayers by solid-state NMR. J Am Chem Soc 133, 4874–4881.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 4874-4881
-
-
Yang, J.1
Aslimovska, L.2
Glaubitz, C.3
-
45
-
-
0026052237
-
Secretion of human epidermal growth factor from Saccharomyces cerevisiae using synthetic leader sequences
-
Clements JM, Catlin GH, Price MJ and Edwards RM (1991) Secretion of human epidermal growth factor from Saccharomyces cerevisiae using synthetic leader sequences. Gene 106, 267–272.
-
(1991)
Gene
, vol.106
, pp. 267-272
-
-
Clements, J.M.1
Catlin, G.H.2
Price, M.J.3
Edwards, R.M.4
-
46
-
-
0029347117
-
Multicopy overexpression of bovine pancreatic trypsin inhibitor saturates the protein folding and secretory capacity of Saccharomyces cerevisiae
-
Parekh R, Forrester K and Witttrup D (1995) Multicopy overexpression of bovine pancreatic trypsin inhibitor saturates the protein folding and secretory capacity of Saccharomyces cerevisiae. Protein Expr Purif 6, 537–545.
-
(1995)
Protein Expr Purif
, vol.6
, pp. 537-545
-
-
Parekh, R.1
Forrester, K.2
Witttrup, D.3
-
47
-
-
77954129578
-
Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids
-
Bryksin AV and Matsumura I (2010) Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids. Biotechniques 48, 463–465.
-
(2010)
Biotechniques
, vol.48
, pp. 463-465
-
-
Bryksin, A.V.1
Matsumura, I.2
-
48
-
-
0036270543
-
Yeast transformation by the LiAc/SS carrier DNA/PEG method
-
Gietz RD and Woods RA (2002) Yeast transformation by the LiAc/SS carrier DNA/PEG method. Methods Enzymol 350, 87–96.
-
(2002)
Methods Enzymol
, vol.350
, pp. 87-96
-
-
Gietz, R.D.1
Woods, R.A.2
-
49
-
-
78049243585
-
Analysis of adenosine A(2)a receptor stability: effects of ligands and disulfide bonds
-
O'Malley MA, Naranjo AN, Lazarova T and Robinson AS (2010) Analysis of adenosine A(2)a receptor stability: effects of ligands and disulfide bonds. Biochemistry 49, 9181–9189.
-
(2010)
Biochemistry
, vol.49
, pp. 9181-9189
-
-
O'Malley, M.A.1
Naranjo, A.N.2
Lazarova, T.3
Robinson, A.S.4
-
50
-
-
12244292640
-
Purification and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli
-
Weiss HM and Grisshammer R (2002) Purification and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli. Eur J Biochem 269, 82–92.
-
(2002)
Eur J Biochem
, vol.269
, pp. 82-92
-
-
Weiss, H.M.1
Grisshammer, R.2
-
51
-
-
55649088213
-
Static light scattering to characterize membrane proteins in detergent solution
-
Slotboom DJ, Duurkens RH, Olieman K and Erkens GB (2008) Static light scattering to characterize membrane proteins in detergent solution. Methods 46, 73–82.
-
(2008)
Methods
, vol.46
, pp. 73-82
-
-
Slotboom, D.J.1
Duurkens, R.H.2
Olieman, K.3
Erkens, G.B.4
-
52
-
-
34547577808
-
Dimerization of the class A G protein-coupled neurotensin receptor NTS1 alters G protein interaction
-
White JF, Grodnitzky J, Louis JM, Trinh LB, Shiloach J, Gutierrez J, Northup JK and Grisshammer R (2007) Dimerization of the class A G protein-coupled neurotensin receptor NTS1 alters G protein interaction. Proc Natl Acad Sci USA 104, 12199–12204.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12199-12204
-
-
White, J.F.1
Grodnitzky, J.2
Louis, J.M.3
Trinh, L.B.4
Shiloach, J.5
Gutierrez, J.6
Northup, J.K.7
Grisshammer, R.8
-
53
-
-
0030571043
-
Size-exclusion chromatography with on-line light-scatterring, absorbance, and refractive index detectors for studying proteins and their interactions
-
Wen J, Arakawa T and Philo JS (1996) Size-exclusion chromatography with on-line light-scatterring, absorbance, and refractive index detectors for studying proteins and their interactions. Anal Biochem 240, 155–166.
-
(1996)
Anal Biochem
, vol.240
, pp. 155-166
-
-
Wen, J.1
Arakawa, T.2
Philo, J.S.3
-
54
-
-
80054687050
-
Toward rational design of protein detergent complexes: determinants of mixed micelles that are critical for the in vitro stabilization of a G-protein coupled receptor
-
O'Malley MA, Helgeson ME, Wagner NJ and Robinson AS (2011) Toward rational design of protein detergent complexes: determinants of mixed micelles that are critical for the in vitro stabilization of a G-protein coupled receptor. Biophys J 101, 1938–1948.
-
(2011)
Biophys J
, vol.101
, pp. 1938-1948
-
-
O'Malley, M.A.1
Helgeson, M.E.2
Wagner, N.J.3
Robinson, A.S.4
-
55
-
-
60549094781
-
Detergent binding explains anomalous SDS-PAGE migration of membrane proteins
-
Rath A, Glibowicka M, Nadeau VG, Chen G and Deber CM (2009) Detergent binding explains anomalous SDS-PAGE migration of membrane proteins. Proc Natl Acad Sci USA 106, 1760–1765.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1760-1765
-
-
Rath, A.1
Glibowicka, M.2
Nadeau, V.G.3
Chen, G.4
Deber, C.M.5
-
56
-
-
35048820405
-
Fluorescence studies of homooligomerization of adenosine A2A and serotonin 5-HT1A receptors reveal the specificity of receptor interactions in the plasma membrane
-
Lukasieqicz S, Blasiak E, Gorecka-Faron A, Polit A, Tworzydlo M, Gorecki A, Wasylewski Z and Dziedzicka-Wasylewska M (2007) Fluorescence studies of homooligomerization of adenosine A2A and serotonin 5-HT1A receptors reveal the specificity of receptor interactions in the plasma membrane. Pharmacol Rep 59, 379–392.
-
(2007)
Pharmacol Rep
, vol.59
, pp. 379-392
-
-
Lukasieqicz, S.1
Blasiak, E.2
Gorecka-Faron, A.3
Polit, A.4
Tworzydlo, M.5
Gorecki, A.6
Wasylewski, Z.7
Dziedzicka-Wasylewska, M.8
-
57
-
-
84960410869
-
Role of extracellular cysteine residues in the adenosine A2a receptor
-
De Filippo E, Namasivayam V, Zappe L, El-Tayeb A, Schiedel AC and Muller CE (2016) Role of extracellular cysteine residues in the adenosine A2a receptor. Purinergic Signal 12, 313–329.
-
(2016)
Purinergic Signal
, vol.12
, pp. 313-329
-
-
De Filippo, E.1
Namasivayam, V.2
Zappe, L.3
El-Tayeb, A.4
Schiedel, A.C.5
Muller, C.E.6
-
58
-
-
84919935016
-
Conserved disulfide bond is not essential for the adenosine A2A receptor: extracellular cysteines influence receptor distribution within the cell and ligand-binding recognition
-
Naranjo AN, Chevalier A, Cousins GD, Ayettey E, McCusker EC, Wenk C and Robinson AS (2015) Conserved disulfide bond is not essential for the adenosine A2A receptor: extracellular cysteines influence receptor distribution within the cell and ligand-binding recognition. Biochim Biophys Acta 1848, 603–614.
-
(2015)
Biochim Biophys Acta
, vol.1848
, pp. 603-614
-
-
Naranjo, A.N.1
Chevalier, A.2
Cousins, G.D.3
Ayettey, E.4
McCusker, E.C.5
Wenk, C.6
Robinson, A.S.7
-
59
-
-
23644444909
-
Refractive index-based determination of detergent concentration and its application to the study of membrane proteins
-
Strop P and Brunger AT (2005) Refractive index-based determination of detergent concentration and its application to the study of membrane proteins. Protein Sci 14, 2207–2211.
-
(2005)
Protein Sci
, vol.14
, pp. 2207-2211
-
-
Strop, P.1
Brunger, A.T.2
-
60
-
-
84944929868
-
Protein-protein interactions: a supra-structural phenomenon demanding trans-disciplinary biophysical approaches
-
Byron O and Vestergaard B (2015) Protein-protein interactions: a supra-structural phenomenon demanding trans-disciplinary biophysical approaches. Curr Opin Struct Biol 35, 76–86.
-
(2015)
Curr Opin Struct Biol
, vol.35
, pp. 76-86
-
-
Byron, O.1
Vestergaard, B.2
-
61
-
-
55249104935
-
Plasma membrane diffusion of G protein-coupled receptor oligomers
-
Briddon SJ, Gandia J, Amaral OB, Ferre S, Lluis C, Franco R, Hill SJ and Ciruela F (2008) Plasma membrane diffusion of G protein-coupled receptor oligomers. Biochim Biophys Acta 1783, 2262–2268.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 2262-2268
-
-
Briddon, S.J.1
Gandia, J.2
Amaral, O.B.3
Ferre, S.4
Lluis, C.5
Franco, R.6
Hill, S.J.7
Ciruela, F.8
-
62
-
-
38849171893
-
NMR spectroscopic and analytical ultracentrifuge analysis of membrane protein detergent complexes
-
Maslennikov I, Kefala G, Johnson C, Riek R, Choe S and Kwiatkowski W (2007) NMR spectroscopic and analytical ultracentrifuge analysis of membrane protein detergent complexes. BMC Struct Biol 7, 74.
-
(2007)
BMC Struct Biol
, vol.7
, pp. 74
-
-
Maslennikov, I.1
Kefala, G.2
Johnson, C.3
Riek, R.4
Choe, S.5
Kwiatkowski, W.6
-
63
-
-
46449094236
-
Stable interactions between the transmembrane domains of the adenosine A2A receptor
-
Thevenin D and Lazarova T (2008) Stable interactions between the transmembrane domains of the adenosine A2A receptor. Protein Sci 17, 1188–1199.
-
(2008)
Protein Sci
, vol.17
, pp. 1188-1199
-
-
Thevenin, D.1
Lazarova, T.2
-
64
-
-
23644460494
-
Oligomerization of the fifth transmembrane domain from the adenosine A2A receptor
-
Thevenin D, Lazarova T, Roberts MF and Robinson CR (2005) Oligomerization of the fifth transmembrane domain from the adenosine A2A receptor. Protein Sci 14, 2177–2186.
-
(2005)
Protein Sci
, vol.14
, pp. 2177-2186
-
-
Thevenin, D.1
Lazarova, T.2
Roberts, M.F.3
Robinson, C.R.4
-
66
-
-
84866056455
-
Assessing the relative stability of dimer interfaces in G protein-coupled receptors
-
Johnston JM, Wang H, Provasi D and Filizola M (2012) Assessing the relative stability of dimer interfaces in G protein-coupled receptors. PLoS Comput Biol 8, e1002649.
-
(2012)
PLoS Comput Biol
, vol.8
-
-
Johnston, J.M.1
Wang, H.2
Provasi, D.3
Filizola, M.4
-
67
-
-
28444493656
-
Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation
-
Guo W, Shi L, Filizola M, Weinstein H and Javitch JA (2005) Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation. Proc Natl Acad Sci USA 102, 17495–17500.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17495-17500
-
-
Guo, W.1
Shi, L.2
Filizola, M.3
Weinstein, H.4
Javitch, J.A.5
|