Surface plasmon resonance spectroscopy for characterisation of membrane protein-ligand interactions and its potential for drug discovery

Biochimica et Biophysica Acta - Biomembranes

Volumn 1838, Issue 1 PARTA, 2014, Pages 43-55

  Patching, Simon G ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Drug discovery; Kinetics; Ligand binding; Membrane protein; Sensors; Surface plasmon resonance

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BETA3; ABC TRANSPORTER; ADENOSINE A2A RECEPTOR; ALPHA HEMOLYSIN; BETA 1 ADRENERGIC RECEPTOR; BETA SECRETASE 1; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; G PROTEIN COUPLED RECEPTOR; LIGAND; MEMBRANE PROTEIN; NEUROPEPTIDE Y4 RECEPTOR; NEUROTENSIN RECEPTOR 1; OLFACTORY RECEPTOR 17 4; PRORENIN RECEPTOR; RHODOPSIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; BINDING AFFINITY; BIOCHIP; BIOPHYSICS; BIOSENSOR; DRUG DEVELOPMENT; DRUG TARGETING; HUMAN; KINETICS; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; REFRACTION INDEX; REVIEW; SPECTROSCOPY; SURFACE PLASMON RESONANCE SPECTROSCOPY;

1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE; 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANESULFONATE; ABC; ADENOSINE-5′-(Β,Γ-IMIDO)TRIPHOSPHATE; ADENOSINE-5′-DIPHOSPHATE; ADENOSINE-5′-MONOPHOSPHATE; ADENOSINE-5′-TRIPHOSPHATE; ADP; AMP; AMPPNP; ATP; ATP BINDING CASSETTE; BACE1; BIOPHYSICAL MAPPING; BPM; CHAPSO; CMC; CRITICAL MICELLE CONCENTRATION; DDM; DRUG DISCOVERY; EGF; EOT; EPIDERMAL GROWTH FACTOR; EXTRAORDINARY OPTICAL TRANSMISSION; G PROTEIN-COUPLED RECEPTOR; GABA; GDP; GPCR; GTP; GUANOSINE-5′-DIPHOSPHATE; GUANOSINE-5′-TRIPHOSPHATE; HOR17-4; HPA; HPRR; HTA; HUMAN (PRO)RENIN RECEPTOR; HUMAN OLFACTORY RECEPTOR 17-4; HYDROPHOBIC ASSOCIATION (SENSOR CHIP); KINETICS; LIGAND BINDING; MEMBRANE PROTEIN; MEMBRANE SCAFFOLD PROTEIN; MSP; N-DODECYL-Β-D-MALTOSIDE; N-Y4; NEUROPEPTIDE Y; NEUROPEPTIDE Y4; NPY; PANCREATIC POLYPEPTIDE; PDB; POLYPEPTIDE YY; POPC; PP; PROTEIN DATA BANK; PYY; RESONANCE OR RESPONSE UNITS; RU; SAM; SDF-1Α; SELF-ASSEMBLED MONOLAYER; SENSORS; SLB; SPR; SPRM; STABILISED RECEPTOR; STAR; STROMAL CELL-DERIVED FACTOR 1Α; SUPPORTED LIPID BILAYER; SURFACE PLASMON RESONANCE; SURFACE PLASMON RESONANCE MICROSCOPY; Β-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1; Γ-AMINOBUTYRIC ACID TYPE A (RECEPTORS); Ω-HYDROXY-UNDECANETHIOL;

DRUG DISCOVERY; LIGANDS; MEMBRANE PROTEINS; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; SURFACE PLASMON RESONANCE;

EID: 84888364004     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2013.04.028     Document Type: Review

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