Analysis of adenosine A2a receptor stability: Effects of ligands and disulfide bonds

Biochemistry

Volumn 49, Issue 43, 2010, Pages 9181-9189

  O'Malley, Michelle A ^a,b   Naranjo, Andrea N ^a   Lazarova, Tzvetana ^a,c   Robinson, Anne S ^a  

^a University of Delaware   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL DENATURATION; CIRCULAR DICHROISM; CONFORMATIONAL STABILITIES; DISULFIDE BONDS; EUKARYOTIC CELLS; EXTRACELLULAR; FLUORESCENCE SPECTROMETRY; G PROTEIN COUPLED RECEPTORS; INTEGRAL MEMBRANE PROTEINS; LIGAND BINDING; LIGAND BINDING ACTIVITY; LIGAND EFFECT; THERMAL DENATURATIONS;

BINDING SITES; BIOINFORMATICS; BIOLOGICAL MEMBRANES; DENATURATION; DICHROISM; FLUORESCENCE SPECTROSCOPY; LIGANDS; PROTEINS; SURFACE ACTIVE AGENTS; UREA;

STABILITY;

ADENOSINE A2A RECEPTOR; CYCLOHEXYLADENOSINE; G PROTEIN COUPLED RECEPTOR; LIGAND; SURFACTANT; THEOPHYLLINE; UREA; ADENOSINE; ADENOSINE A2 RECEPTOR; DISULFIDE; DRUG DERIVATIVE; N(6) CYCLOHEXYLADENOSINE; N(6)-CYCLOHEXYLADENOSINE;

ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DENATURATION; DISULFIDE BOND; EXTRACELLULAR MATRIX; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STABILITY; SPECTROFLUOROMETRY; CHEMISTRY; DRUG EFFECT; HUMAN; METABOLISM; PROTEIN DENATURATION;

EUKARYOTA;

ADENOSINE; DISULFIDES; HUMANS; LIGANDS; PROTEIN DENATURATION; PROTEIN STABILITY; RECEPTORS, ADENOSINE A2; RECEPTORS, G-PROTEIN-COUPLED; THEOPHYLLINE;

EID: 78049243585     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101155r     Document Type: Article

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