Engineered T cells: The promise and challenges of cancer immunotherapy

Nature Reviews Cancer

Volumn 16, Issue 9, 2016, Pages 566-581

  Fesnak, Andrew D ^a   June, Carl H ^a   Levine, Bruce L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR; CD19 ANTIGEN; CD19 MOLECULE, HUMAN; CYTOKINE; HLA ANTIGEN; HYBRID PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; TUMOR ANTIGEN;

ADOPTIVE TRANSFER; CANCER IMMUNOTHERAPY; CELL ENGINEERING; CELL GROWTH; CLINICAL TRIAL (TOPIC); HEMATOLOGIC MALIGNANCY; HUMAN; IMMUNE EVASION; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SOLID TUMOR; T LYMPHOCYTE; TUMOR MICROENVIRONMENT; ADOPTIVE IMMUNOTHERAPY; ADVERSE EFFECTS; ANTIGEN PRESENTATION; BIOLOGICAL MODEL; FORECASTING; GENE EDITING; GENE TRANSFER; GENETIC ENGINEERING; GENETICS; HEMATOLOGIC NEOPLASMS; IMMUNOLOGY; NEOPLASMS; PROCEDURES; SECRETION (PROCESS); SYNDROME; T LYMPHOCYTE SUBPOPULATION; TRANSPLANTATION; TRENDS; TUMOR ESCAPE;

ANTIGEN PRESENTATION; ANTIGENS, CD19; ANTIGENS, NEOPLASM; CLINICAL TRIALS AS TOPIC; COSTIMULATORY AND INHIBITORY T-CELL RECEPTORS; CYTOKINES; FORECASTING; GENE EDITING; GENE TRANSFER TECHNIQUES; GENETIC ENGINEERING; HEMATOLOGIC NEOPLASMS; HLA ANTIGENS; HUMANS; IMMUNOTHERAPY, ADOPTIVE; MODELS, IMMUNOLOGICAL; NEOPLASMS; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SYNDROME; T-CELL ANTIGEN RECEPTOR SPECIFICITY; T-LYMPHOCYTE SUBSETS; TUMOR ESCAPE; TUMOR MICROENVIRONMENT;

EID: 84984677958     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc.2016.97     Document Type: Review

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