Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

Cell

Volumn 164, Issue 4, 2016, Pages 780-791

  Morsut, Leonardo ^a,b,c   Roybal, Kole T ^a,b,c   Xiong, Xin ^a,b,c   Gordley, Russell M ^a,b,c   Coyle, Scott M ^a,b,c   Thomson, Matthew ^a,b   Lim, Wendell A ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL RECEPTOR; CD19 ANTIGEN; CRE RECOMBINASE; GREEN FLUORESCENT PROTEIN; MYOD PROTEIN; NOTCH RECEPTOR; SYNTHETIC NOTCH RECEPTOR; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CONTACT; CELL ENGINEERING; CELL FATE; CELL FUNCTION; CELL INTERACTION; CELL TRANSDIFFERENTIATION; CHIMERA; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; RAT; TRANSCRIPTION INITIATION; ANIMAL; CELL LINE; CHEMISTRY; DOG; GENETIC TRANSCRIPTION; METABOLISM; NERVE CELL; PROCEDURES; SIGNAL TRANSDUCTION; SYNTHETIC BIOLOGY;

ANIMALS; CELL ENGINEERING; CELL LINE; DOGS; HUMANS; MICE; NEURONS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; SYNTHETIC BIOLOGY; TRANSCRIPTION, GENETIC;

EID: 84958230998     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.01.012     Document Type: Article

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