메뉴 건너뛰기




Volumn 105, Issue 16, 2013, Pages 1172-1187

MHC class i antigen processing and presenting machinery: Organization, function, and defects in tumor cells

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; AMINOPEPTIDASE; CALNEXIN; CALRETICULIN; CELL PROTEIN; CHAPERONE; DIPEPTIDASE; GAMMA UROGASTRONE; HLA A11 ANTIGEN; HLA A3 ANTIGEN; HLA ANTIGEN CLASS 1; HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2; INTERFERON REGULATORY FACTOR 1; JANUS KINASE 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MELAN A; PROTEASOME; STAT1 PROTEIN; T LYMPHOCYTE RECEPTOR; TAPASIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 1; TRANSCRIPTION FACTOR E2F; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 84883157468     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djt184     Document Type: Review
Times cited : (410)

References (209)
  • 1
    • 82755187338 scopus 로고    scopus 로고
    • Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting
    • Ciechanover A. Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting. Biochim Biophys Acta. 2012;1824(1):3-13.
    • (2012) Biochim Biophys Acta. , vol.1824 , Issue.1 , pp. 3-13
    • Ciechanover, A.1
  • 2
    • 82755189571 scopus 로고    scopus 로고
    • The endosome-lysosome pathway and information generation in the immune system
    • Watts C. The endosome-lysosome pathway and information generation in the immune system. Biochim Biophys Acta. 2012;1824(1):14-21.
    • (2012) Biochim Biophys Acta. , vol.1824 , Issue.1 , pp. 14-21
    • Watts, C.1
  • 3
    • 0036083396 scopus 로고    scopus 로고
    • The ubiquitin-proteasome proteo-lytic pathway: Destruction for the sake of construction
    • Glickman MH, Ciechanover A. The ubiquitin-proteasome proteo-lytic pathway: destruction for the sake of construction. Physiol Rev. 2002;82(2):373-428.
    • (2002) Physiol Rev. , vol.82 , Issue.2 , pp. 373-428
    • Glickman, M.H.1    Ciechanover, A.2
  • 4
    • 0346727127 scopus 로고    scopus 로고
    • Protein degradation and protection against misfolded or damaged proteins
    • Goldberg AL. Protein degradation and protection against misfolded or damaged proteins. Nature. 2003;426(6968):895-899.
    • (2003) Nature. , vol.426 , Issue.6968 , pp. 895-899
    • Goldberg, A.L.1
  • 5
    • 0034643336 scopus 로고    scopus 로고
    • Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
    • Schubert U, Anton LC, Gibbs J, Norbury CC, Yewdell JW, Bennink JR. Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature. 2000;404(6779):770-774.
    • (2000) Nature. , vol.404 , Issue.6779 , pp. 770-774
    • Schubert, U.1    Anton, L.C.2    Gibbs, J.3    Norbury, C.C.4    Yewdell, J.W.5    Bennink, J.R.6
  • 6
    • 0035060172 scopus 로고    scopus 로고
    • At the crossroads of cell biology and immunology: DRiPs and other sources of peptide ligands for MHC class i molecules
    • Yewdell JW, Schubert U, Bennink JR. At the crossroads of cell biology and immunology: DRiPs and other sources of peptide ligands for MHC class I molecules. J Cell Sci. 2001;114(Pt 5):845-851.
    • (2001) J Cell Sci. , vol.114 , Issue.PART 5 , pp. 845-851
    • Yewdell, J.W.1    Schubert, U.2    Bennink, J.R.3
  • 7
    • 0035399848 scopus 로고    scopus 로고
    • Not such a dismal science: The economics of protein synthesis folding, degradation and antigen processing
    • Yewdell JW. Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing. Trends Cell Biol. 2001;11(7):294-297.
    • (2001) Trends Cell Biol. , vol.11 , Issue.7 , pp. 294-297
    • Yewdell, J.W.1
  • 9
    • 84859159747 scopus 로고    scopus 로고
    • NK cell MHC class i specific receptors (KIR): From biology to clinical intervention
    • Thielens A, Vivier E, Romagne F. NK cell MHC class I specific receptors (KIR): from biology to clinical intervention. Curr Opin Immunol. 2012;24(2):239-245.
    • (2012) Curr Opin Immunol. , vol.24 , Issue.2 , pp. 239-245
    • Thielens, A.1    Vivier, E.2    Romagne, F.3
  • 10
    • 0033525589 scopus 로고    scopus 로고
    • A novel ubiquitination factor E4, is involved in multiubiquitin chain assembly
    • Koegl M, Hoppe T, Schlenker S, Ulrich HD, Mayer TU, Jentsch S. A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell. 1999;96(5):635-644.
    • (1999) Cell. , vol.96 , Issue.5 , pp. 635-644
    • Koegl, M.1    Hoppe, T.2    Schlenker, S.3    Ulrich, H.D.4    Mayer, T.U.5    Jentsch, S.6
  • 11
    • 0037290828 scopus 로고    scopus 로고
    • Assembly and export of MHC class i peptide ligands
    • Antoniou AN, Powis SJ, Elliott T. Assembly and export of MHC class I peptide ligands. Curr Opin Immunol. 2003;15(1):75-81.
    • (2003) Curr Opin Immunol. , vol.15 , Issue.1 , pp. 75-81
    • Antoniou, A.N.1    Powis, S.J.2    Elliott, T.3
  • 12
    • 34548736008 scopus 로고    scopus 로고
    • Recent advances in antigen processing and presentation
    • Jensen PE. Recent advances in antigen processing and presentation. Nat Immunol. 2007;8(10):1041-1048.
    • (2007) Nat Immunol. , vol.8 , Issue.10 , pp. 1041-1048
    • Jensen, P.E.1
  • 13
    • 0035290730 scopus 로고    scopus 로고
    • Antigen processing by the proteasome
    • Kloetzel PM. Antigen processing by the proteasome. Nat Rev Mol Cell Biol. 2001;2(3):179-187.
    • (2001) Nat Rev Mol Cell Biol. , vol.2 , Issue.3 , pp. 179-187
    • Kloetzel, P.M.1
  • 14
    • 0037290852 scopus 로고    scopus 로고
    • Antigen processing and recognition
    • Sant A, Yewdell J. Antigen processing and recognition. Curr Opin Immunol. 2003;15(1):66-68.
    • (2003) Curr Opin Immunol. , vol.15 , Issue.1 , pp. 66-68
    • Sant, A.1    Yewdell, J.2
  • 15
    • 26244435436 scopus 로고    scopus 로고
    • The seven dirty little secrets of major histocompatibility complex class i antigen processing
    • Yewdell JW. The seven dirty little secrets of major histocompatibility complex class I antigen processing. Immunol Rev. 2005;207:8-18.
    • (2005) Immunol Rev. , vol.207 , pp. 8-18
    • Yewdell, J.W.1
  • 16
    • 0029071646 scopus 로고
    • Functions of the proteasome: The lysis at the end of the tunnel
    • Goldberg AL. Functions of the proteasome: the lysis at the end of the tunnel. Science. 1995;268(5210):522-523.
    • (1995) Science. , vol.268 , Issue.5210 , pp. 522-523
    • Goldberg, A.L.1
  • 17
    • 9644289334 scopus 로고    scopus 로고
    • The proteasome and MHC class i antigen processing
    • Kloetzel PM. The proteasome and MHC class I antigen processing. Biochim Biophys Acta. 2004;1695(1-3):225-233.
    • (2004) Biochim Biophys Acta. , vol.1695 , Issue.1-3 , pp. 225-233
    • Kloetzel, P.M.1
  • 18
    • 0027414074 scopus 로고
    • The multicatalytic and 26 S proteases
    • Rechsteiner M, Hoffman L, Dubiel W. The multicatalytic and 26 S proteases. J Biol Chem. 1993;268(9):6065-6068.
    • (1993) J Biol Chem. , vol.268 , Issue.9 , pp. 6065-6068
    • Rechsteiner, M.1    Hoffman, L.2    Dubiel, W.3
  • 19
    • 0032476030 scopus 로고    scopus 로고
    • Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants
    • Dick TP, Nussbaum AK, Deeg M, et al. Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants. J Biol Chem. 1998;273(40):25637-25646.
    • (1998) J Biol Chem. , vol.273 , Issue.40 , pp. 25637-25646
    • Dick, T.P.1    Nussbaum, A.K.2    Deeg, M.3
  • 20
    • 0030774890 scopus 로고    scopus 로고
    • The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing
    • Heinemeyer W, Fischer M, Krimmer T, Stachon U, Wolf DH. The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing. J Biol Chem. 1997;272(40):25200-25209.
    • (1997) J Biol Chem. , vol.272 , Issue.40 , pp. 25200-25209
    • Heinemeyer, W.1    Fischer, M.2    Krimmer, T.3    Stachon, U.4    Wolf, D.H.5
  • 21
    • 0033766480 scopus 로고    scopus 로고
    • A gated channel into the proteasome core particle
    • Groll M, Bajorek M, Kohler A, et al. A gated channel into the proteasome core particle. Nat Struct Biol. 2000;7(11):1062-1067.
    • (2000) Nat Struct Biol. , vol.7 , Issue.11 , pp. 1062-1067
    • Groll, M.1    Bajorek, M.2    Kohler, A.3
  • 22
    • 0032867676 scopus 로고    scopus 로고
    • The 26S proteasome: A molecular machine designed for controlled proteolysis
    • Voges D, Zwickl P, Baumeister W. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem. 1999;68:1015-1068.
    • (1999) Annu Rev Biochem. , vol.68 , pp. 1015-1068
    • Voges, D.1    Zwickl, P.2    Baumeister, W.3
  • 23
    • 0033119024 scopus 로고    scopus 로고
    • Functional analysis of the protea-some regulatory particle
    • Glickman MH, Rubin DM, Fu H, et al. Functional analysis of the protea-some regulatory particle. Mol Biol Rep. 1999;26(1-2):21-28.
    • (1999) Mol Biol Rep. , vol.26 , Issue.1-2 , pp. 21-28
    • Glickman, M.H.1    Rubin, D.M.2    Fu, H.3
  • 24
    • 0033176770 scopus 로고    scopus 로고
    • The base of the protea-some regulatory particle exhibits chaperone-like activity
    • Braun BC, Glickman M, Kraft R, et al. The base of the protea-some regulatory particle exhibits chaperone-like activity. Nat Cell Biol. 1999;1(4):221-226.
    • (1999) Nat Cell Biol. , vol.1 , Issue.4 , pp. 221-226
    • Braun, B.C.1    Glickman, M.2    Kraft, R.3
  • 25
    • 0034090632 scopus 로고    scopus 로고
    • Recognition of mis-folding proteins by PA700, the regulatory subcomplex of the 26 S protea-some
    • Strickland E, Hakala K, Thomas PJ, DeMartino GN. Recognition of mis-folding proteins by PA700, the regulatory subcomplex of the 26 S protea-some. J Biol Chem. 2000;275(8):5565-5572.
    • (2000) J Biol Chem. , vol.275 , Issue.8 , pp. 5565-5572
    • Strickland, E.1    Hakala, K.2    Thomas, P.J.3    Demartino, G.N.4
  • 27
    • 0036646488 scopus 로고    scopus 로고
    • PA200, a nuclear pro-teasome activator involved in DNA repair
    • Ustrell V, Hoffman L, Pratt G, Rechsteiner M. PA200, a nuclear pro-teasome activator involved in DNA repair. EMBO J. 2002;21(13): 3516-3525.
    • (2002) EMBO J. , vol.21 , Issue.13 , pp. 3516-3525
    • Ustrell, V.1    Hoffman, L.2    Pratt, G.3    Rechsteiner, M.4
  • 28
    • 0034674655 scopus 로고    scopus 로고
    • CDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome
    • Cutchen-Maloney SL, Matsuda K, Shimbara N, et al. cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome. J Biol Chem. 2000;275(24):18557-18565.
    • (2000) J Biol Chem. , vol.275 , Issue.24 , pp. 18557-18565
    • Cutchen-Maloney, S.L.1    Matsuda, K.2    Shimbara, N.3
  • 29
    • 0032828077 scopus 로고    scopus 로고
    • The proteasome inhibitor PI31 competes with PA28 for binding to 20S proteasomes
    • Zaiss DM, Standera S, Holzhutter H, Kloetzel P, Sijts AJ. The proteasome inhibitor PI31 competes with PA28 for binding to 20S proteasomes. FEBS Lett. 1999;457(3):333-338.
    • (1999) FEBS Lett. , vol.457 , Issue.3 , pp. 333-338
    • Zaiss, D.M.1    Standera, S.2    Holzhutter, H.3    Kloetzel, P.4    Sijts, A.J.5
  • 30
    • 0034597824 scopus 로고    scopus 로고
    • Structural basis for the activation of 20S proteasomes by 11S regulators
    • Whitby FG, Masters EI, Kramer L, et al. Structural basis for the activation of 20S proteasomes by 11S regulators. Nature. 2000;408(6808):115-120.
    • (2000) Nature. , vol.408 , Issue.6808 , pp. 115-120
    • Whitby, F.G.1    Masters, E.I.2    Kramer, L.3
  • 31
    • 0031973736 scopus 로고    scopus 로고
    • Immunoproteasome assembly: Cooperative incorporation of interferon gamma (IFN-gamma)-inducible subu-nits
    • Griffin TA, Nandi D, Cruz M, et al. Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subu-nits. J Exp Med. 1998;187(1):97-104.
    • (1998) J Exp Med. , vol.187 , Issue.1 , pp. 97-104
    • Griffin, T.A.1    Nandi, D.2    Cruz, M.3
  • 32
    • 0030793290 scopus 로고    scopus 로고
    • The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome
    • Groettrup M, Standera S, Stohwasser R, Kloetzel PM. The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome. Proc Natl Acad Sci USA. 1997;94(17):8970-8975.
    • (1997) Proc Natl Acad Sci USA. , vol.94 , Issue.17 , pp. 8970-8975
    • Groettrup, M.1    Standera, S.2    Stohwasser, R.3    Kloetzel, P.M.4
  • 33
    • 0030880547 scopus 로고    scopus 로고
    • Intermediates in the formation of mouse 20S proteasomes: Implications for the assembly of precursor beta subunits
    • Nandi D, Woodward E, Ginsburg DB, Monaco JJ. Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits. EMBO J. 1997;16(17):5363-5375.
    • (1997) EMBO J. , vol.16 , Issue.17 , pp. 5363-5375
    • Nandi, D.1    Woodward, E.2    Ginsburg, D.B.3    Monaco, J.J.4
  • 34
    • 0028179233 scopus 로고
    • Interferon-gamma induces different subunit organizations and functional diversity of proteasomes
    • Aki M, Shimbara N, Takashina M, et al. Interferon-gamma induces different subunit organizations and functional diversity of proteasomes. J Biochem. 1994;115(2):257-269.
    • (1994) J Biochem. , vol.115 , Issue.2 , pp. 257-269
    • Aki, M.1    Shimbara, N.2    Takashina, M.3
  • 35
    • 33750597617 scopus 로고    scopus 로고
    • Virus-induced type i IFN stimulates generation of immunoproteasomes at the site of infection
    • Shin EC, Seifert U, Kato T, et al. Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection. J Clin Invest. 2006;116(11):3006-3014.
    • (2006) J Clin Invest. , vol.116 , Issue.11 , pp. 3006-3014
    • Shin, E.C.1    Seifert, U.2    Kato, T.3
  • 36
    • 0030898161 scopus 로고    scopus 로고
    • Molecular cloning of the mouse proteasome subunits MC14 and MECL-1: Reciprocally regulated tissue expression of interferon-gamma-modulated proteasome subunits
    • Stohwasser R, Standera S, Peters I, Kloetzel PM, Groettrup M. Molecular cloning of the mouse proteasome subunits MC14 and MECL-1: reciprocally regulated tissue expression of interferon-gamma-modulated proteasome subunits. Eur J Immunol. 1997;27(5):1182-1187.
    • (1997) Eur J Immunol. , vol.27 , Issue.5 , pp. 1182-1187
    • Stohwasser, R.1    Standera, S.2    Peters, I.3    Kloetzel, P.M.4    Groettrup, M.5
  • 37
    • 0032730872 scopus 로고    scopus 로고
    • Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation
    • Macagno A, Gilliet M, Sallusto F, Lanzavecchia A, Nestle FO, Groettrup M. Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation. Eur J Immunol. 1999;29(12):4037-4042.
    • (1999) Eur J Immunol. , vol.29 , Issue.12 , pp. 4037-4042
    • MacAgno, A.1    Gilliet, M.2    Sallusto, F.3    Lanzavecchia, A.4    Nestle, F.O.5    Groettrup, M.6
  • 38
    • 0028136465 scopus 로고
    • Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7
    • Gaczynska M, Rock KL, Spies T, Goldberg AL. Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7. Proc Natl Acad Sci USA. 1994;91(20):9213-9217.
    • (1994) Proc Natl Acad Sci USA. , vol.91 , Issue.20 , pp. 9213-9217
    • Gaczynska, M.1    Rock, K.L.2    Spies, T.3    Goldberg, A.L.4
  • 39
    • 0035796461 scopus 로고    scopus 로고
    • Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products
    • Toes RE, Nussbaum AK, Degermann S, et al. Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products. J Exp Med. 2001;194(1):1-12.
    • (2001) J Exp Med. , vol.194 , Issue.1 , pp. 1-12
    • Toes, R.E.1    Nussbaum, A.K.2    Degermann, S.3
  • 40
    • 0035806246 scopus 로고    scopus 로고
    • Immuno-proteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens
    • Chen W, Norbury CC, Cho Y, Yewdell JW, Bennink JR. Immuno-proteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens. J Exp Med. 2001;193(11):1319-1326.
    • (2001) J Exp Med. , vol.193 , Issue.11 , pp. 1319-1326
    • Chen, W.1    Norbury, C.C.2    Cho, Y.3    Yewdell, J.W.4    Bennink, J.R.5
  • 41
    • 77958505473 scopus 로고    scopus 로고
    • Ontogenesis of rat immune system: Proteasome expression in different cell populations of the developing thymus
    • Melnikova VI, Sharova N P, Maslova EV, Voronova SN, Zakharova LA. Ontogenesis of rat immune system: proteasome expression in different cell populations of the developing thymus. Cell Immunol. 2010;266(1):83-89.
    • (2010) Cell Immunol. , vol.266 , Issue.1 , pp. 83-89
    • Melnikova, V.I.1    Sharova, N.P.2    Maslova, E.V.3    Voronova, S.N.4    Zakharova, L.A.5
  • 42
    • 0036401590 scopus 로고    scopus 로고
    • Immunoproteasome expression in a nonimmune tissue, the ocular lens
    • Singh S, Awasthi N, Egwuagu CE, Wagner BJ. Immunoproteasome expression in a nonimmune tissue, the ocular lens. Arch Biochem Biophys. 2002;405(2):147-153.
    • (2002) Arch Biochem Biophys. , vol.405 , Issue.2 , pp. 147-153
    • Singh, S.1    Awasthi, N.2    Egwuagu, C.E.3    Wagner, B.J.4
  • 43
    • 0034614889 scopus 로고    scopus 로고
    • Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes
    • Sijts AJ, Ruppert T, Rehermann B, Schmidt M, Koszinowski U, Kloetzel PM. Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes. J Exp Med. 2000;191(3):503-514.
    • (2000) J Exp Med. , vol.191 , Issue.3 , pp. 503-514
    • Sijts, A.J.1    Ruppert, T.2    Rehermann, B.3    Schmidt, M.4    Koszinowski, U.5    Kloetzel, P.M.6
  • 44
    • 84855921130 scopus 로고    scopus 로고
    • Mice completely lacking immuno-proteasomes show major changes in antigen presentation
    • Kincaid EZ, Che JW, York I, et al. Mice completely lacking immuno-proteasomes show major changes in antigen presentation. Nat Immunol. 2012;13(2):129-135.
    • (2012) Nat Immunol. , vol.13 , Issue.2 , pp. 129-135
    • Kincaid, E.Z.1    Che, J.W.2    York, I.3
  • 45
    • 0030886208 scopus 로고    scopus 로고
    • Tw o distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide
    • Craiu A, Akopian T, Goldberg A, Rock KL. Tw o distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide. Proc Natl Acad Sci USA. 1997;94(20):10850-10855.
    • (1997) Proc Natl Acad Sci USA. , vol.94 , Issue.20 , pp. 10850-10855
    • Craiu, A.1    Akopian, T.2    Goldberg, A.3    Rock, K.L.4
  • 46
    • 34247146913 scopus 로고    scopus 로고
    • The final touches make perfect the peptide-MHC class i repertoire
    • Hammer GE, Kanaseki T, Shastri N. The final touches make perfect the peptide-MHC class I repertoire. Immunity. 2007;26(4):397-406.
    • (2007) Immunity. , vol.26 , Issue.4 , pp. 397-406
    • Hammer, G.E.1    Kanaseki, T.2    Shastri, N.3
  • 47
    • 0037242017 scopus 로고    scopus 로고
    • Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class i
    • Reits E, Griekspoor A, Neijssen J, et al. Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I. Immunity. 2003;18(1):97-108.
    • (2003) Immunity. , vol.18 , Issue.1 , pp. 97-108
    • Reits, E.1    Griekspoor, A.2    Neijssen, J.3
  • 48
    • 0031858602 scopus 로고    scopus 로고
    • Allelic differences in the relationship between proteasome activity and MHC class i peptide loading
    • Benham AM, Gromme M, Neefjes J. Allelic differences in the relationship between proteasome activity and MHC class I peptide loading. J Immunol. 1998;161(1):83-89.
    • (1998) J Immunol. , vol.161 , Issue.1 , pp. 83-89
    • Benham, A.M.1    Gromme, M.2    Neefjes, J.3
  • 49
    • 0033548055 scopus 로고    scopus 로고
    • A giant protease with potential to substitute for some functions of the proteasome
    • Geier E, Pfeifer G, Wilm M, et al. A giant protease with potential to substitute for some functions of the proteasome. Science. 1999;283(5404):978- 981.
    • (1999) Science. , vol.283 , Issue.5404 , pp. 978-981
    • Geier, E.1    Pfeifer, G.2    Wilm, M.3
  • 50
    • 0037386260 scopus 로고    scopus 로고
    • An essential role for tripeptidyl peptidase in the generation of an MHC class i epitope
    • Seifert U, Maranon C, Shmueli A, et al. An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope. Nat Immunol. 2003;4(4):375-379.
    • (2003) Nat Immunol. , vol.4 , Issue.4 , pp. 375-379
    • Seifert, U.1    Maranon, C.2    Shmueli, A.3
  • 52
    • 71049153709 scopus 로고    scopus 로고
    • Cancer/testis (CT) antigens: Potential targets for immunotherapy
    • Caballero OL, Chen YT. Cancer/testis (CT) antigens: potential targets for immunotherapy. Cancer Sci. 2009;100(11):2014-2021.
    • (2009) Cancer Sci. , vol.100 , Issue.11 , pp. 2014-2021
    • Caballero, O.L.1    Chen, Y.T.2
  • 53
    • 78650310807 scopus 로고    scopus 로고
    • Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes
    • Kessler JH, Khan S, Seifert U, et al. Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes. Nat Immunol. 2011;12(1):45-53.
    • (2011) Nat Immunol. , vol.12 , Issue.1 , pp. 45-53
    • Kessler, J.H.1    Khan, S.2    Seifert, U.3
  • 54
    • 0034907526 scopus 로고    scopus 로고
    • MHC class i molecules can direct proteolytic cleavage of antigenic precursors in the endoplasmic reticulum
    • Brouwenstijn N, Serwold T, Shastri N. MHC class I molecules can direct proteolytic cleavage of antigenic precursors in the endoplasmic reticulum. Immunity. 2001;15(1):95-104.
    • (2001) Immunity. , vol.15 , Issue.1 , pp. 95-104
    • Brouwenstijn, N.1    Serwold, T.2    Shastri, N.3
  • 55
    • 0034802622 scopus 로고    scopus 로고
    • Efficient MHC class I-independent amino-terminal trimming of epitope precursor pep-tides in the endoplasmic reticulum
    • Fruci D, Niedermann G, Butler RH, van Endert PM. Efficient MHC class I-independent amino-terminal trimming of epitope precursor pep-tides in the endoplasmic reticulum. Immunity. 2001;15(3):467-476.
    • (2001) Immunity. , vol.15 , Issue.3 , pp. 467-476
    • Fruci, D.1    Niedermann, G.2    Butler, R.H.3    Van Endert, P.M.4
  • 56
    • 28044456942 scopus 로고    scopus 로고
    • The ER aminopeptidase ERAP1 trims precursors to lengths of MHC class i peptides by a "molecular ruler" mechanism
    • Chang SC, Momburg F, Bhutani N, Goldberg AL. The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism. Proc Natl Acad Sci USA. 2005;102(47):17107-17112.
    • (2005) Proc Natl Acad Sci USA. , vol.102 , Issue.47 , pp. 17107-17112
    • Chang, S.C.1    Momburg, F.2    Bhutani, N.3    Goldberg, A.L.4
  • 57
    • 38049039851 scopus 로고    scopus 로고
    • Proteasome activator and antigen-processing aminopeptidases are regulated by virus-induced type i inter-feron in the hepatitis C virus-infected liver
    • Shin EC, Seifert U, Urban S, et al. Proteasome activator and antigen-processing aminopeptidases are regulated by virus-induced type I inter-feron in the hepatitis C virus-infected liver. J Interferon Cytokine Res. 2007;27(12):985-990.
    • (2007) J Interferon Cytokine Res. , vol.27 , Issue.12 , pp. 985-990
    • Shin, E.C.1    Seifert, U.2    Urban, S.3
  • 58
    • 80054927947 scopus 로고    scopus 로고
    • The carboxypeptidase ACE shapes the MHC class i peptide repertoire
    • Shen XZ, Billet S, Lin C, et al. The carboxypeptidase ACE shapes the MHC class I peptide repertoire. Nat Immunol. 2011;12(11):1078-1085.
    • (2011) Nat Immunol. , vol.12 , Issue.11 , pp. 1078-1085
    • Shen, X.Z.1    Billet, S.2    Lin, C.3
  • 59
    • 0036909285 scopus 로고    scopus 로고
    • Structure and mechanism of ABC transporters
    • Schmitt L, Tampe R. Structure and mechanism of ABC transporters. Curr Opin Struct Biol. 2002;12(6):754-60.
    • (2002) Curr Opin Struct Biol. , vol.12 , Issue.6 , pp. 754-760
    • Schmitt, L.1    Tampe, R.2
  • 60
    • 0035912749 scopus 로고    scopus 로고
    • Use of chimeric proteins to investigate the role of transporter associated with antigen processing (TAP) structural domains in peptide binding and translocation
    • Arora S, Lapinski PE, Raghavan M. Use of chimeric proteins to investigate the role of transporter associated with antigen processing (TAP) structural domains in peptide binding and translocation. Proc Natl Acad Sci USA. 2001;98(13):7241-7246.
    • (2001) Proc Natl Acad Sci USA. , vol.98 , Issue.13 , pp. 7241-7246
    • Arora, S.1    Lapinski, P.E.2    Raghavan, M.3
  • 61
    • 4744358624 scopus 로고    scopus 로고
    • The ATP switch model for ABC transporters
    • Higgins CF, Linton KJ. The ATP switch model for ABC transporters. Nat Struct Mol Biol. 2004;11(10):918-926.
    • (2004) Nat Struct Mol Biol. , vol.11 , Issue.10 , pp. 918-926
    • Higgins, C.F.1    Linton, K.J.2
  • 62
    • 77955895736 scopus 로고    scopus 로고
    • ABC proteins in antigen translocation and viral inhibition
    • Parcej D, Tampe R. ABC proteins in antigen translocation and viral inhibition. Nat Chem Biol. 2010;6(8):572-580.
    • (2010) Nat Chem Biol. , vol.6 , Issue.8 , pp. 572-580
    • Parcej, D.1    Tampe, R.2
  • 63
    • 79952167215 scopus 로고    scopus 로고
    • Conformation of peptides bound to the transporter associated with antigen processing (TAP)
    • Herget M, Baldauf C, Scholz C, et al. Conformation of peptides bound to the transporter associated with antigen processing (TAP). Proc Natl Acad Sci USA. 2011;108(4):1349-1354.
    • (2011) Proc Natl Acad Sci USA. , vol.108 , Issue.4 , pp. 1349-1354
    • Herget, M.1    Baldauf, C.2    Scholz, C.3
  • 64
    • 0029809474 scopus 로고    scopus 로고
    • Translocation of long peptides by transporters associated with antigen processing (TAP)
    • Koopmann JO, Post M, Neefjes JJ, Hammerling GJ, Momburg F. Translocation of long peptides by transporters associated with antigen processing (TAP). Eur J Immunol. 1996;26(8):1720-1728.
    • (1996) Eur J Immunol. , vol.26 , Issue.8 , pp. 1720-1728
    • Koopmann, J.O.1    Post, M.2    Neefjes, J.J.3    Hammerling, G.J.4    Momburg, F.5
  • 66
    • 0028198644 scopus 로고
    • Peptide size selection by the major histocompatibility complex-encoded peptide transporter
    • Momburg F, Roelse J, Hammerling GJ, Neefjes JJ. Peptide size selection by the major histocompatibility complex-encoded peptide transporter. J Exp Med. 1994;179(5):1613-1623.
    • (1994) J Exp Med. , vol.179 , Issue.5 , pp. 1613-1623
    • Momburg, F.1    Roelse, J.2    Hammerling, G.J.3    Neefjes, J.J.4
  • 67
    • 0031978551 scopus 로고    scopus 로고
    • Generation and TAP-mediated transport of peptides for major histocompatibility complex class i molecules
    • Momburg F, Hammerling GJ. Generation and TAP-mediated transport of peptides for major histocompatibility complex class I molecules. Adv Immunol. 1998;68:191-256.
    • (1998) Adv Immunol. , vol.68 , pp. 191-256
    • Momburg, F.1    Hammerling, G.J.2
  • 69
    • 0027943180 scopus 로고
    • Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling
    • Roelse J, Gromme M, Momburg F, Hammerling G, Neefjes J. Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling. J Exp Med. 1994;180(5):1591-1597.
    • (1994) J Exp Med. , vol.180 , Issue.5 , pp. 1591-1597
    • Roelse, J.1    Gromme, M.2    Momburg, F.3    Hammerling, G.4    Neefjes, J.5
  • 70
    • 0035253721 scopus 로고    scopus 로고
    • A role for calnexin in the assembly of the MHC class i loading complex in the endoplasmic reticu-lum
    • Diedrich G, Bangia N, Pan M, Cresswell P. A role for calnexin in the assembly of the MHC class I loading complex in the endoplasmic reticu-lum. J Immunol. 2001;166(3):1703-179.
    • (2001) J Immunol. , vol.166 , Issue.3 , pp. 1703-2179
    • Diedrich, G.1    Bangia, N.2    Pan, M.3    Cresswell, P.4
  • 71
    • 0032482384 scopus 로고    scopus 로고
    • The thiol oxidoreductase ERp57 is a component of the MHC class i peptide-loading complex
    • Hughes EA, Cresswell P. The thiol oxidoreductase ERp57 is a component of the MHC class I peptide-loading complex. Curr Biol. 1998;8(12):709-712.
    • (1998) Curr Biol. , vol.8 , Issue.12 , pp. 709-712
    • Hughes, E.A.1    Cresswell, P.2
  • 72
    • 0032482385 scopus 로고    scopus 로고
    • A role for the thiol-dependent reductase ERp57 in the assembly of MHC class i molecules
    • Morrice NA, Powis SJ. A role for the thiol-dependent reductase ERp57 in the assembly of MHC class I molecules. Curr Biol. 1998;8(12):713-76.
    • (1998) Curr Biol. , vol.8 , Issue.12 , pp. 713-776
    • Morrice, N.A.1    Powis, S.J.2
  • 73
    • 0030217926 scopus 로고    scopus 로고
    • Roles for cal-reticulin and a novel glycoprotein, tapasin, in the interaction of MHC class i molecules with TAP
    • Sadasivan B, Lehner PJ, Ortmann B, Spies T, Cresswell P. Roles for cal-reticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP. Immunity. 1996;5(2):103-114.
    • (1996) Immunity. , vol.5 , Issue.2 , pp. 103-114
    • Sadasivan, B.1    Lehner, P.J.2    Ortmann, B.3    Spies, T.4    Cresswell, P.5
  • 74
    • 0036776746 scopus 로고    scopus 로고
    • Tapasin-the keystone of the loading complex optimizing peptide binding by MHC class i molecules in the endoplasmic reticu-lum
    • Momburg F, Tan P. Tapasin-the keystone of the loading complex optimizing peptide binding by MHC class I molecules in the endoplasmic reticu-lum. Mol Immunol. 2002;39(3-4):217-233.
    • (2002) Mol Immunol. , vol.39 , Issue.3-4 , pp. 217-233
    • Momburg, F.1    Tan, P.2
  • 75
    • 0030865333 scopus 로고    scopus 로고
    • A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes
    • Ortmann B, Copeman J, Lehner PJ, et al. A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes. Science. 1997;277(5330):1306-1309.
    • (1997) Science. , vol.277 , Issue.5330 , pp. 1306-1309
    • Ortmann, B.1    Copeman, J.2    Lehner, P.J.3
  • 76
    • 0036166431 scopus 로고    scopus 로고
    • Disulfide bond isomeriza-tion and the assembly of MHC class I-peptide complexes
    • Dick T P, Bangia N, Peaper DR, Cresswell P. Disulfide bond isomeriza-tion and the assembly of MHC class I-peptide complexes. Immunity. 2002;16(1):87-98.
    • (2002) Immunity. , vol.16 , Issue.1 , pp. 87-98
    • Dick, T.P.1    Bangia, N.2    Peaper, D.R.3    Cresswell, P.4
  • 77
    • 0028282108 scopus 로고
    • MHC class I/beta 2-microglob-ulin complexes associate with TAP transporters before peptide binding
    • Ortmann B, Androlewicz MJ, Cresswell P. MHC class I/beta 2-microglob-ulin complexes associate with TAP transporters before peptide binding. Nature. 1994;368(6474):864-867.
    • (1994) Nature. , vol.368 , Issue.6474 , pp. 864-867
    • Ortmann, B.1    Androlewicz, M.J.2    Cresswell, P.3
  • 78
    • 5044224594 scopus 로고    scopus 로고
    • Tapasin and other chaperones: Models of the MHC class i loading complex
    • Wright CA, Kozik P, Zacharias M, Springer S. Tapasin and other chaperones: models of the MHC class I loading complex. Biol Chem. 2004;385(9):763-778.
    • (2004) Biol Chem. , vol.385 , Issue.9 , pp. 763-778
    • Wright, C.A.1    Kozik, P.2    Zacharias, M.3    Springer, S.4
  • 79
    • 0028103695 scopus 로고
    • Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control
    • Hammond C, Braakman I, Helenius A. Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control. Proc Natl Acad Sci USA. 1994;91(3):913-917.
    • (1994) Proc Natl Acad Sci USA. , vol.91 , Issue.3 , pp. 913-917
    • Hammond, C.1    Braakman, I.2    Helenius, A.3
  • 80
    • 0029134004 scopus 로고
    • Chaperone function of cal-reticulin when expressed in the endoplasmic reticulum as the membrane-anchored and soluble forms
    • Wada I, Imai S, Kai M, Sakane F, Kanoh H. Chaperone function of cal-reticulin when expressed in the endoplasmic reticulum as the membrane-anchored and soluble forms. J Biol Chem. 1995;270(35):20298-20304.
    • (1995) J Biol Chem. , vol.270 , Issue.35 , pp. 20298-20304
    • Wada, I.1    Imai, S.2    Kai, M.3    Sakane, F.4    Kanoh, H.5
  • 81
    • 0032807338 scopus 로고    scopus 로고
    • ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin
    • Oliver JD, Roderick HL, Llewellyn DH, High S. ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin. Mol Biol Cell. 1999;10(8):2573-2582.
    • (1999) Mol Biol Cell. , vol.10 , Issue.8 , pp. 2573-2582
    • Oliver, J.D.1    Roderick, H.L.2    Llewellyn, D.H.3    High, S.4
  • 82
    • 0035424237 scopus 로고    scopus 로고
    • ER quality control: Towards an understanding at the molecular level
    • Ellgaard L, Helenius A. ER quality control: towards an understanding at the molecular level. Curr Opin Cell Biol. 2001;13(4):431-437.
    • (2001) Curr Opin Cell Biol. , vol.13 , Issue.4 , pp. 431-437
    • Ellgaard, L.1    Helenius, A.2
  • 83
    • 0026528005 scopus 로고
    • Efficient dissociation of the p88 chaperone from major histocompatibility complex class i molecules requires both beta 2-microglobulin and peptide
    • Degen E, Cohen-Doyle MF, Williams DB. Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2-microglobulin and peptide. J Exp Med. 1992;175(6):1653-1661.
    • (1992) J Exp Med. , vol.175 , Issue.6 , pp. 1653-1661
    • Degen, E.1    Cohen-Doyle, M.F.2    Williams, D.B.3
  • 84
    • 0028917887 scopus 로고
    • Species-specific differences in chaperone interaction of human and mouse major histocompatibility complex class i molecules
    • Nossner E, Parham P. Species-specific differences in chaperone interaction of human and mouse major histocompatibility complex class I molecules. J Exp Med. 1995;181(1):327-337.
    • (1995) J Exp Med. , vol.181 , Issue.1 , pp. 327-337
    • Nossner, E.1    Parham, P.2
  • 85
    • 0032005348 scopus 로고    scopus 로고
    • Soluble tapasin restores MHC class i expression and function in the tapasin-negative cell line.220
    • Lehner PJ, Surman MJ, Cresswell P. Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line.220. Immunity. 1998;8(2):221-231.
    • (1998) Immunity. , vol.8 , Issue.2 , pp. 221-231
    • Lehner, P.J.1    Surman, M.J.2    Cresswell, P.3
  • 86
    • 0030981737 scopus 로고    scopus 로고
    • Regulation of MHC class i heterodimer stability and interaction with TAP by tapasin
    • Grandea AG, III, Lehner PJ, Cresswell P, Spies T. Regulation of MHC class I heterodimer stability and interaction with TAP by tapasin. Immunogenetics. 1997;46(6):477-483.
    • (1997) Immunogenetics. , vol.46 , Issue.6 , pp. 477-483
    • Grandea, A.G.1    Lehner III, P.J.2    Cresswell, P.3    Spies, T.4
  • 87
    • 0036230677 scopus 로고    scopus 로고
    • Optimization of the MHC class i peptide cargo is dependent on tapasin
    • Williams AP, Peh CA, Purcell AW, McCluskey J, Elliott T. Optimization of the MHC class I peptide cargo is dependent on tapasin. Immunity. 2002;16(4):509-520.
    • (2002) Immunity. , vol.16 , Issue.4 , pp. 509-520
    • Williams, A.P.1    Peh, C.A.2    Purcell, A.W.3    McCluskey, J.4    Elliott, T.5
  • 88
    • 22244434945 scopus 로고    scopus 로고
    • Immunoselective pressure and human leukocyte antigen class i antigen machinery defects in microsatellite unstable colorectal cancers
    • Kloor M, Becker C, Benner A, et al. Immunoselective pressure and human leukocyte antigen class I antigen machinery defects in microsatellite unstable colorectal cancers. Cancer Res. 2005;65(14):6418-6424.
    • (2005) Cancer Res. , vol.65 , Issue.14 , pp. 6418-6424
    • Kloor, M.1    Becker, C.2    Benner, A.3
  • 89
    • 73349138887 scopus 로고    scopus 로고
    • Relationship between HLA class i antigen processing machinery component expression and the clinicopathologic characteristics of bladder carcinomas
    • Cathro H P, Smolkin ME, Theodorescu D, Jo VY, Ferrone S, Frierson HF Jr. Relationship between HLA class I antigen processing machinery component expression and the clinicopathologic characteristics of bladder carcinomas. Cancer Immunol Immunother. 2010;59(3):465-472.
    • (2010) Cancer Immunol Immunother. , vol.59 , Issue.3 , pp. 465-472
    • Cathro, H.P.1    Smolkin, M.E.2    Theodorescu, D.3    Jo, V.Y.4    Ferrone, S.5    Frierson Jr., H.F.6
  • 90
    • 64149122759 scopus 로고    scopus 로고
    • Down-regulation of protea-somal subunit MB1 is an independent predictor of improved survival in ovarian cancer
    • Leffers N, Gooden MJ, Mokhova AA, et al. Down-regulation of protea-somal subunit MB1 is an independent predictor of improved survival in ovarian cancer. Gynecol Oncol. 2009;113(2):256-263.
    • (2009) Gynecol Oncol. , vol.113 , Issue.2 , pp. 256-263
    • Leffers, N.1    Gooden, M.J.2    Mokhova, A.A.3
  • 91
    • 34347256375 scopus 로고    scopus 로고
    • Expression and functional analysis of human leukocyte antigen class i antigen-processing machinery in medulloblastoma
    • Raffaghello L, Nozza P, Morandi F, et al. Expression and functional analysis of human leukocyte antigen class I antigen-processing machinery in medulloblastoma. Cancer Res. 2007;67(11):5471-5478.
    • (2007) Cancer Res. , vol.67 , Issue.11 , pp. 5471-5478
    • Raffaghello, L.1    Nozza, P.2    Morandi, F.3
  • 92
    • 67349124848 scopus 로고    scopus 로고
    • In situ analysis of the antigen-processing machinery in acute myeloid leukaemic blasts by tissue microarray
    • Hoves S, Aigner M, Pfeiffer C, Laumer M, Obermann EC, Mackensen A. In situ analysis of the antigen-processing machinery in acute myeloid leukaemic blasts by tissue microarray. Leukemia. 2009;23(5):877-85.
    • (2009) Leukemia. , vol.23 , Issue.5 , pp. 877-885
    • Hoves, S.1    Aigner, M.2    Pfeiffer, C.3    Laumer, M.4    Obermann, E.C.5    MacKensen, A.6
  • 93
    • 17644413210 scopus 로고    scopus 로고
    • Defects in the human leukocyte antigen class i antigen processing machinery in head and neck squa-mous cell carcinoma: Association with clinical outcome
    • Meissner M, Reichert TE, Kunkel M, et al. Defects in the human leukocyte antigen class I antigen processing machinery in head and neck squa-mous cell carcinoma: association with clinical outcome. Clin Cancer Res. 2005;11(7):2552-2560.
    • (2005) Clin Cancer Res. , vol.11 , Issue.7 , pp. 2552-2560
    • Meissner, M.1    Reichert, T.E.2    Kunkel, M.3
  • 94
    • 33749504503 scopus 로고    scopus 로고
    • HLA class i antigen down-regulation in primary laryngeal squamous cell carcinoma lesions as a poor prognostic marker
    • Ogino T, Shigyo H, Ishii H, et al. HLA class I antigen down-regulation in primary laryngeal squamous cell carcinoma lesions as a poor prognostic marker. Cancer Res. 2006;66(18):9281-9289.
    • (2006) Cancer Res. , vol.66 , Issue.18 , pp. 9281-9289
    • Ogino, T.1    Shigyo, H.2    Ishii, H.3
  • 95
    • 70350686895 scopus 로고    scopus 로고
    • Down-regulation of HLA class i antigen-processing machinery components in esophageal squamous cell carcinomas: Association with disease progression
    • Liu Q, Hao C, Su P, Shi J. Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: association with disease progression. Scand J Gastroenterol. 2009;44(8):960-969.
    • (2009) Scand J Gastroenterol. , vol.44 , Issue.8 , pp. 960-969
    • Liu, Q.1    Hao, C.2    Su, P.3    Shi, J.4
  • 96
    • 79951735484 scopus 로고    scopus 로고
    • Methylation of the promoter of human leukocyte antigen class i in human esophageal squa-mous cell carcinoma and its histopathological characteristics
    • Qifeng S, Bo C, Xingtao J, Chuanliang P, Xiaogang Z. Methylation of the promoter of human leukocyte antigen class I in human esophageal squa-mous cell carcinoma and its histopathological characteristics. J Thorac Cardiovasc Surg. 2011;141(3):808-814.
    • (2011) J Thorac Cardiovasc Surg. , vol.141 , Issue.3 , pp. 808-814
    • Qifeng, S.1    Bo, C.2    Xingtao, J.3    Chuanliang, P.4    Xiaogang, Z.5
  • 97
    • 79551702601 scopus 로고    scopus 로고
    • Association of defective HLA-I expression with antigen processing machinery and their association with clinicopathological characteristics in Kazak patients with esophageal cancer
    • Ayshamgul H, Ma H, Ilyar S, Zhang LW, Abulizi A. Association of defective HLA-I expression with antigen processing machinery and their association with clinicopathological characteristics in Kazak patients with esophageal cancer. Chin Med J (Engl). 2011;124(3):341-346.
    • (2011) Chin Med J (Engl). , vol.124 , Issue.3 , pp. 341-346
    • Ayshamgul, H.1    Ma, H.2    Ilyar, S.3    Zhang, L.W.4    Abulizi, A.5
  • 98
    • 33947646821 scopus 로고    scopus 로고
    • Characterization of the immune escape phenotype of human gastric cancers with and without high-frequency microsatellite instability
    • Hirata T, Yamamoto H, Taniguchi H, et al. Characterization of the immune escape phenotype of human gastric cancers with and without high-frequency microsatellite instability. J Pathol. 2007;211(5):516-523.
    • (2007) J Pathol. , vol.211 , Issue.5 , pp. 516-523
    • Hirata, T.1    Yamamoto, H.2    Taniguchi, H.3
  • 99
    • 1242319374 scopus 로고    scopus 로고
    • MHC class i antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma
    • Atkins D, Breuckmann A, Schmahl GE, et al. MHC class I antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma. Int J Cancer. 2004;109(2):265-273.
    • (2004) Int J Cancer. , vol.109 , Issue.2 , pp. 265-273
    • Atkins, D.1    Breuckmann, A.2    Schmahl, G.E.3
  • 100
    • 33847787987 scopus 로고    scopus 로고
    • HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class i expression
    • Dierssen JW, de Miranda NF, Ferrone S, et al. HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression. BMC Cancer. 2007;7:33.
    • (2007) BMC Cancer. , vol.7 , pp. 33
    • Dierssen, J.W.1    De Miranda, N.F.2    Ferrone, S.3
  • 101
    • 0347759811 scopus 로고    scopus 로고
    • Down-regulation of HLA class i antigen processing molecules: An immune escape mechanism of renal cell carcinoma?
    • Atkins D, Ferrone S, Schmahl GE, Storkel S, Seliger B. Down-regulation of HLA class I antigen processing molecules: an immune escape mechanism of renal cell carcinoma? J Urol. 2004;171(2 Pt 1):885-889.
    • (2004) J Urol. , vol.171 , Issue.2 PART 1 , pp. 885-889
    • Atkins, D.1    Ferrone, S.2    Schmahl, G.E.3    Storkel, S.4    Seliger, B.5
  • 102
    • 0038666364 scopus 로고    scopus 로고
    • Characterization of human lymphocyte antigen class i antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation
    • Seliger B, Atkins D, Bock M, et al. Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation. Clin Cancer Res. 2003;9(5):1721-1727.
    • (2003) Clin Cancer Res. , vol.9 , Issue.5 , pp. 1721-1727
    • Seliger, B.1    Atkins, D.2    Bock, M.3
  • 103
    • 11144286431 scopus 로고    scopus 로고
    • Coordinated downregulation of the antigen presentation machinery and HLA class I/beta2-microglobulin complex is responsible for HLA-ABC loss in bladder cancer
    • Romero JM, Jimenez P, Cabrera T, et al. Coordinated downregulation of the antigen presentation machinery and HLA class I/beta2-microglobulin complex is responsible for HLA-ABC loss in bladder cancer. Int J Cancer. 2005;113(4):605-610.
    • (2005) Int J Cancer. , vol.113 , Issue.4 , pp. 605-610
    • Romero, J.M.1    Jimenez, P.2    Cabrera, T.3
  • 104
    • 77449133036 scopus 로고    scopus 로고
    • Association of HLA class i antigen abnormalities with disease progression and early recurrence in prostate cancer
    • Seliger B, Stoehr R, Handke D, et al. Association of HLA class I antigen abnormalities with disease progression and early recurrence in prostate cancer. Cancer Immunol Immunother. 2010;59(4):529-540.
    • (2010) Cancer Immunol Immunother. , vol.59 , Issue.4 , pp. 529-540
    • Seliger, B.1    Stoehr, R.2    Handke, D.3
  • 105
    • 84866375600 scopus 로고    scopus 로고
    • Post-transcriptional and epi-genetic regulation of antigen processing machinery (APM) components and HLA-I in cervical cancers from Uighur women
    • Hasim A, Abudula M, Aimiduo R, et al. Post-transcriptional and epi-genetic regulation of antigen processing machinery (APM) components and HLA-I in cervical cancers from Uighur women. PLoS One. 2012;7(9):e44952.
    • (2012) PLoS One. , vol.7 , Issue.9
    • Hasim, A.1    Abudula, M.2    Aimiduo, R.3
  • 106
    • 36349025846 scopus 로고    scopus 로고
    • Association of antigen processing machinery and HLA class i defects with clinico-pathological outcome in cervical carcinoma
    • Mehta AM, Jordanova ES, Kenter GG, Ferrone S, Fleuren GJ. Association of antigen processing machinery and HLA class I defects with clinico-pathological outcome in cervical carcinoma. Cancer Immunol Immunother. 2008;57(2):197-206.
    • (2008) Cancer Immunol Immunother. , vol.57 , Issue.2 , pp. 197-206
    • Mehta, A.M.1    Jordanova, E.S.2    Kenter, G.G.3    Ferrone, S.4    Fleuren, G.J.5
  • 107
    • 16644371597 scopus 로고    scopus 로고
    • Expression of HLA class i antigen and proteasome subunits LMP-2 and LMP-10 in primary vs. Meta-static breast carcinoma lesions
    • Gobbi G, Mirandola P, Micheloni C, et al. Expression of HLA class I antigen and proteasome subunits LMP-2 and LMP-10 in primary vs. meta-static breast carcinoma lesions. Int J Oncol. 2004;25(6):1625-1629.
    • (2004) Int J Oncol. , vol.25 , Issue.6 , pp. 1625-1629
    • Gobbi, G.1    Mirandola, P.2    Micheloni, C.3
  • 108
    • 84862337169 scopus 로고    scopus 로고
    • Expression of antigen processing and presenting molecules in brain metastasis of breast cancer
    • Liu Y, Komohara Y, Domenick N, et al. Expression of antigen processing and presenting molecules in brain metastasis of breast cancer. Cancer Immunol Immunother. 2012;61(6):789-801.
    • (2012) Cancer Immunol Immunother. , vol.61 , Issue.6 , pp. 789-801
    • Liu, Y.1    Komohara, Y.2    Domenick, N.3
  • 109
    • 34547112565 scopus 로고    scopus 로고
    • WHO grade associated down-regulation of MHC class i antigen-processing machinery components in human astrocytomas: Does it reflect a potential immune escape mechanism?
    • Mehling M, Simon P, Mittelbronn M, et al. WHO grade associated down-regulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism? Acta Neuropathol. 2007;114(2):111-119.
    • (2007) Acta Neuropathol. , vol.114 , Issue.2 , pp. 111-119
    • Mehling, M.1    Simon, P.2    Mittelbronn, M.3
  • 110
    • 22744453776 scopus 로고    scopus 로고
    • Multiple defects of the antigen-processing machinery components in human neuroblastoma: Immuno-therapeutic implications
    • Raffaghello L, Prigione I, Bocca P, et al. Multiple defects of the antigen-processing machinery components in human neuroblastoma: immuno-therapeutic implications. Oncogene. 2005;24(29):4634-4644.
    • (2005) Oncogene. , vol.24 , Issue.29 , pp. 4634-4644
    • Raffaghello, L.1    Prigione, I.2    Bocca, P.3
  • 111
    • 0033034333 scopus 로고    scopus 로고
    • Down-regulation of HLA class i antigen-processing molecules in malignant melanoma: Association with disease progression
    • Kageshita T, Hirai S, Ono T, Hicklin DJ, Ferrone S. Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: association with disease progression. Am J Pathol. 1999;154(3):745-754.
    • (1999) Am J Pathol. , vol.154 , Issue.3 , pp. 745-754
    • Kageshita, T.1    Hirai, S.2    Ono, T.3    Hicklin, D.J.4    Ferrone, S.5
  • 112
    • 0035915772 scopus 로고    scopus 로고
    • TAP1 down-regulation in primary melanoma lesions: An independent marker of poor prognosis
    • Kamarashev J, Ferrone S, Seifert B, et al. TAP1 down-regulation in primary melanoma lesions: an independent marker of poor prognosis. Int J Cancer. 2001;95(1):23-28.
    • (2001) Int J Cancer. , vol.95 , Issue.1 , pp. 23-28
    • Kamarashev, J.1    Ferrone, S.2    Seifert, B.3
  • 113
    • 77949537596 scopus 로고    scopus 로고
    • Alterations in the antigen processing-presenting machinery of transformed plasma cells are associated with reduced recognition by CD8+ T cells and characterize the progression of MGUS to multiple myeloma
    • Racanelli V, Leone P, Frassanito MA, et al. Alterations in the antigen processing-presenting machinery of transformed plasma cells are associated with reduced recognition by CD8+ T cells and characterize the progression of MGUS to multiple myeloma. Blood. 2010;115(6):1185-1193.
    • (2010) Blood. , vol.115 , Issue.6 , pp. 1185-1193
    • Racanelli, V.1    Leone, P.2    Frassanito, M.A.3
  • 114
    • 34247529384 scopus 로고    scopus 로고
    • Genetic variation of antigen processing machinery components and association with cervical carcinoma
    • Mehta AM, Jordanova ES, van Wezel T, et al. Genetic variation of antigen processing machinery components and association with cervical carcinoma. Genes Chromosomes Cancer. 2007;46(6):577-586.
    • (2007) Genes Chromosomes Cancer. , vol.46 , Issue.6 , pp. 577-586
    • Mehta, A.M.1    Jordanova, E.S.2    Van Wezel, T.3
  • 115
    • 0034667381 scopus 로고    scopus 로고
    • Loss of interferon-gamma induc-ibility of TAP1 and LMP2 in a renal cell carcinoma cell line
    • Dovhey SE, Ghosh NS, Wright KL. Loss of interferon-gamma induc-ibility of TAP1 and LMP2 in a renal cell carcinoma cell line. Cancer Res. 2000;60(20):5789-5796.
    • (2000) Cancer Res. , vol.60 , Issue.20 , pp. 5789-5796
    • Dovhey, S.E.1    Ghosh, N.S.2    Wright, K.L.3
  • 116
    • 79955495231 scopus 로고    scopus 로고
    • Association of IFN-gamma signal trans-duction defects with impaired HLA class i antigen processing in melanoma cell lines
    • Respa A, Bukur J, Ferrone S, et al. Association of IFN-gamma signal trans-duction defects with impaired HLA class I antigen processing in melanoma cell lines. Clin Cancer Res. 2011;17(9):2668-2678.
    • (2011) Clin Cancer Res. , vol.17 , Issue.9 , pp. 2668-2678
    • Respa, A.1    Bukur, J.2    Ferrone, S.3
  • 117
    • 77949448480 scopus 로고    scopus 로고
    • HLA class i antigen and transporter associated with antigen processing downregulation in metastatic lesions of head and neck squamous cell carcinoma as a marker of poor prognosis
    • Bandoh N, Ogino T, Katayama A, et al. HLA class I antigen and transporter associated with antigen processing downregulation in metastatic lesions of head and neck squamous cell carcinoma as a marker of poor prognosis. Oncol Rep. 2010;23(4):933-939.
    • (2010) Oncol Rep. , vol.23 , Issue.4 , pp. 933-939
    • Bandoh, N.1    Ogino, T.2    Katayama, A.3
  • 118
    • 0032586280 scopus 로고    scopus 로고
    • HLA class i expression and chromosomal deletions at 6p and 15q in head and neck squamous cell carcinomas
    • Feenstra M, Veltkamp M, van Kuik J, et al. HLA class I expression and chromosomal deletions at 6p and 15q in head and neck squamous cell carcinomas. Tissue Antigens. 1999;54(3):235-245.
    • (1999) Tissue Antigens. , vol.54 , Issue.3 , pp. 235-245
    • Feenstra, M.1    Veltkamp, M.2    Van Kuik, J.3
  • 119
    • 33644839506 scopus 로고    scopus 로고
    • Role of antigen-processing machinery in the in vitro resistance of squamous cell carcinoma of the head and neck cells to recognition by CTL
    • Lopez-Albaitero A, Nayak JV, Ogino T, et al. Role of antigen-processing machinery in the in vitro resistance of squamous cell carcinoma of the head and neck cells to recognition by CTL. J Immunol. 2006;176(6):3402-3409.
    • (2006) J Immunol. , vol.176 , Issue.6 , pp. 3402-3409
    • Lopez-Albaitero, A.1    Nayak, J.V.2    Ogino, T.3
  • 120
    • 77957861323 scopus 로고    scopus 로고
    • Trastuzumab mediated T-cell response against HER-2/neu overexpressing esophageal ade-nocarcinoma depends on intact antigen processing machinery
    • Milano F, Guarriera M, Rygiel AM, Krishnadath KK. Trastuzumab mediated T-cell response against HER-2/neu overexpressing esophageal ade-nocarcinoma depends on intact antigen processing machinery. PLoS One. 2010;5(8):e12424.
    • (2010) PLoS One. , vol.5 , Issue.8
    • Milano, F.1    Guarriera, M.2    Rygiel, A.M.3    Krishnadath, K.K.4
  • 121
    • 33847684243 scopus 로고    scopus 로고
    • Loss of expression of antigen-presenting molecules in human pancreatic cancer and pancreatic cancer cell lines
    • Pandha H, Rigg A, John J, Lemoine N. Loss of expression of antigen-presenting molecules in human pancreatic cancer and pancreatic cancer cell lines. Clin Exp Immunol. 2007;148(1):127-135.
    • (2007) Clin Exp Immunol. , vol.148 , Issue.1 , pp. 127-135
    • Pandha, H.1    Rigg, A.2    John, J.3    Lemoine, N.4
  • 122
    • 68849119061 scopus 로고    scopus 로고
    • MUTYH-associated polyposis carcinomas frequently lose HLA class i expression-a common event amongst DNA-repair-deficient colorectal cancers
    • de Miranda NF, Nielsen M, Pereira D, et al. MUTYH-associated polyposis carcinomas frequently lose HLA class I expression-a common event amongst DNA-repair-deficient colorectal cancers. J Pathol. 2009;219(1):69-76.
    • (2009) J Pathol. , vol.219 , Issue.1 , pp. 69-76
    • De Miranda, N.F.1    Nielsen, M.2    Pereira, D.3
  • 123
    • 0028094647 scopus 로고
    • Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer
    • Kaklamanis L, Townsend A, Doussis-Anagnostopoulou IA, Mortensen N, Harris AL, Gatter KC. Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer. Am J Pathol. 1994;145(3):505-509.
    • (1994) Am J Pathol. , vol.145 , Issue.3 , pp. 505-509
    • Kaklamanis, L.1    Townsend, A.2    Doussis-Anagnostopoulou, I.A.3    Mortensen, N.4    Harris, A.L.5    Gatter, K.C.6
  • 124
    • 78449285664 scopus 로고    scopus 로고
    • Down-regulation of the antigen processing machinery is linked to a loss of inflammatory response in colorectal cancer
    • Kasajima A, Sers C, Sasano H, et al. Down-regulation of the antigen processing machinery is linked to a loss of inflammatory response in colorectal cancer. Hum Pathol. 2010;41(12):1758-1769.
    • (2010) Hum Pathol. , vol.41 , Issue.12 , pp. 1758-1769
    • Kasajima, A.1    Sers, C.2    Sasano, H.3
  • 125
    • 0034068643 scopus 로고    scopus 로고
    • TAP expression provides a general method for improving the recognition of malignant cells in vivo
    • Alimonti J, Zhang QJ, Gabathuler R, Reid G, Chen SS, Jefferies WA. TAP expression provides a general method for improving the recognition of malignant cells in vivo. Nat Biotechnol. 2000;18(5):515-20.
    • (2000) Nat Biotechnol. , vol.18 , Issue.5 , pp. 515-520
    • Alimonti, J.1    Zhang, Q.J.2    Gabathuler, R.3    Reid, G.4    Chen, S.S.5    Jefferies, W.A.6
  • 126
    • 0028789344 scopus 로고
    • Loss of transporter in antigen processing 1 transport protein and major histocom-patibility complex class i molecules in metastatic versus primary breast cancer
    • Kaklamanis L, Leek R, Koukourakis M, Gatter KC, Harris AL. Loss of transporter in antigen processing 1 transport protein and major histocom-patibility complex class I molecules in metastatic versus primary breast cancer. Cancer Res. 1995;55(22):5191-5194.
    • (1995) Cancer Res. , vol.55 , Issue.22 , pp. 5191-5194
    • Kaklamanis, L.1    Leek, R.2    Koukourakis, M.3    Gatter, K.C.4    Harris, A.L.5
  • 127
    • 0032520053 scopus 로고    scopus 로고
    • HLA class i antigen and transporter associated with antigen processing (TAP1 and TAP2) down-regulation in high-grade primary breast carcinoma lesions
    • Vitale M, Rezzani R, Rodella L, et al. HLA class I antigen and transporter associated with antigen processing (TAP1 and TAP2) down-regulation in high-grade primary breast carcinoma lesions. Cancer Res. 1998;58(4):737-742.
    • (1998) Cancer Res. , vol.58 , Issue.4 , pp. 737-742
    • Vitale, M.1    Rezzani, R.2    Rodella, L.3
  • 128
    • 0028012028 scopus 로고
    • Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas
    • Cromme F V, Airey J, Heemels MT, et al. Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas. J Exp Med. 1994;179(1):335-340.
    • (1994) J Exp Med. , vol.179 , Issue.1 , pp. 335-340
    • Cromme, F.V.1    Airey, J.2    Heemels, M.T.3
  • 129
    • 1342343088 scopus 로고    scopus 로고
    • Mutations in TAP genes are common in cervical carcinomas
    • Fowler NL, Frazer IH. Mutations in TAP genes are common in cervical carcinomas. Gynecol Oncol. 2004;92(3):914-921.
    • (2004) Gynecol Oncol. , vol.92 , Issue.3 , pp. 914-921
    • Fowler, N.L.1    Frazer, I.H.2
  • 130
    • 0035650718 scopus 로고    scopus 로고
    • Deficient expression of components of the MHC class i antigen processing machinery in human cervical carcinoma
    • Ritz U, Momburg F, Pilch H, Huber C, Maeurer MJ, Seliger B. Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma. Int J Oncol. 2001;19(6):1211-1220.
    • (2001) Int J Oncol. , vol.19 , Issue.6 , pp. 1211-1220
    • Ritz, U.1    Momburg, F.2    Pilch, H.3    Huber, C.4    Maeurer, M.J.5    Seliger, B.6
  • 131
    • 0037502775 scopus 로고    scopus 로고
    • Association of TAP1 downregulation in human primary melanoma lesions with lack of spontaneous regression
    • Dissemond J, Gotte P, Mors J, et al. Association of TAP1 downregulation in human primary melanoma lesions with lack of spontaneous regression. Melanoma Res. 2003;13(3):253-258.
    • (2003) Melanoma Res. , vol.13 , Issue.3 , pp. 253-258
    • Dissemond, J.1    Gotte, P.2    Mors, J.3
  • 132
    • 0035893563 scopus 로고    scopus 로고
    • Immune escape of melanoma: First evidence of structural alterations in two distinct components of the MHC class i antigen processing pathway
    • Seliger B, Ritz U, Abele R, et al. Immune escape of melanoma: first evidence of structural alterations in two distinct components of the MHC class I antigen processing pathway. Cancer Res. 2001;61(24):8647-8650.
    • (2001) Cancer Res. , vol.61 , Issue.24 , pp. 8647-8650
    • Seliger, B.1    Ritz, U.2    Abele, R.3
  • 133
    • 0038350469 scopus 로고    scopus 로고
    • A single-nucleotide deletion leads to rapid degradation of TAP-1 mRNA in a melanoma cell line
    • Yang T, McNally BA, Ferrone S, Liu Y, Zheng P. A single-nucleotide deletion leads to rapid degradation of TAP-1 mRNA in a melanoma cell line. J Biol Chem. 2003;278(17):15291-15296.
    • (2003) J Biol Chem. , vol.278 , Issue.17 , pp. 15291-15296
    • Yang, T.1    McNally, B.A.2    Ferrone, S.3    Liu, Y.4    Zheng, P.5
  • 134
    • 28544444135 scopus 로고    scopus 로고
    • Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors
    • Facoetti A, Nano R, Zelini P, et al. Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors. Clin Cancer Res. 2005;11(23):8304-8311.
    • (2005) Clin Cancer Res. , vol.11 , Issue.23 , pp. 8304-8311
    • Facoetti, A.1    Nano, R.2    Zelini, P.3
  • 135
    • 0032478256 scopus 로고    scopus 로고
    • Induction of transporter associated with antigen processing by interferon gamma confers endothelial cell cytoprotection against natural killer-mediated lysis
    • Ayalon O, Hughes EA, Cresswell P, et al. Induction of transporter associated with antigen processing by interferon gamma confers endothelial cell cytoprotection against natural killer-mediated lysis. Proc Natl Acad Sci USA. 1998;95(5):2435-2440.
    • (1998) Proc Natl Acad Sci USA. , vol.95 , Issue.5 , pp. 2435-2440
    • Ayalon, O.1    Hughes, E.A.2    Cresswell, P.3
  • 136
    • 0030999544 scopus 로고    scopus 로고
    • Interferon-gamma rapidly increases peptide transporter (TAP) subunit expression and peptide transport capacity in endothelial cells
    • Ma W, Lehner PJ, Cresswell P, Pober JS, Johnson DR. Interferon-gamma rapidly increases peptide transporter (TAP) subunit expression and peptide transport capacity in endothelial cells. J Biol Chem. 1997;272(26):16585-16590.
    • (1997) J Biol Chem. , vol.272 , Issue.26 , pp. 16585-16590
    • Ma, W.1    Lehner, P.J.2    Cresswell, P.3    Pober, J.S.4    Johnson, D.R.5
  • 137
    • 65349123542 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma
    • Mehta AM, Jordanova ES, Corver WE, et al. Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma. Genes Chromosomes Cancer. 2009;48(5):410-418.
    • (2009) Genes Chromosomes Cancer. , vol.48 , Issue.5 , pp. 410-418
    • Mehta, A.M.1    Jordanova, E.S.2    Corver, W.E.3
  • 138
    • 0030043695 scopus 로고    scopus 로고
    • A functionally defective allele of TAP1 results in loss of MHC class i antigen presentation in a human lung cancer
    • Chen HL, Gabrilovich D, Tampe R, Girgis KR, Nadaf S, Carbone D P. A functionally defective allele of TAP1 results in loss of MHC class I antigen presentation in a human lung cancer. Nat Genet. 1996;13(2):210-213.
    • (1996) Nat Genet. , vol.13 , Issue.2 , pp. 210-213
    • Chen, H.L.1    Gabrilovich, D.2    Tampe, R.3    Girgis, K.R.4    Nadaf, S.5    Carbone, D.P.6
  • 139
    • 0035893563 scopus 로고    scopus 로고
    • Immune escape of melanoma: First evidence of structural alterations in two distinct components of the MHC class i antigen processing pathway
    • Seliger B, Ritz U, Abele R, et al. Immune escape of melanoma: first evidence of structural alterations in two distinct components of the MHC class I antigen processing pathway. Cancer Res. 2001;61(24):8647-8650.
    • (2001) Cancer Res. , vol.61 , Issue.24 , pp. 8647-8650
    • Seliger, B.1    Ritz, U.2    Abele, R.3
  • 140
    • 48749106928 scopus 로고    scopus 로고
    • Altered expression of endoplas-mic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues
    • Fruci D, Giacomini P, Nicotra MR, et al. Altered expression of endoplas-mic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues. J Cell Physiol. 2008;216(3):742-749.
    • (2008) J Cell Physiol. , vol.216 , Issue.3 , pp. 742-749
    • Fruci, D.1    Giacomini, P.2    Nicotra, M.R.3
  • 141
    • 77953229217 scopus 로고    scopus 로고
    • Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma
    • Kamphausen E, Kellert C, Abbas T, et al. Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma. Cancer Immunol Immunother. 2010;59(8):1273-1284.
    • (2010) Cancer Immunol Immunother. , vol.59 , Issue.8 , pp. 1273-1284
    • Kamphausen, E.1    Kellert, C.2    Abbas, T.3
  • 142
    • 0141790816 scopus 로고    scopus 로고
    • Association of tapasin and HLA class i antigen down-regulation in primary maxillary sinus squamous cell carcinoma lesions with reduced survival of patients
    • Ogino T, Bandoh N, Hayashi T, Miyokawa N, Harabuchi Y, Ferrone S. Association of tapasin and HLA class I antigen down-regulation in primary maxillary sinus squamous cell carcinoma lesions with reduced survival of patients. Clin Cancer Res. 2003;9(11):4043-4051.
    • (2003) Clin Cancer Res. , vol.9 , Issue.11 , pp. 4043-4051
    • Ogino, T.1    Bandoh, N.2    Hayashi, T.3    Miyokawa, N.4    Harabuchi, Y.5    Ferrone, S.6
  • 143
    • 0035137084 scopus 로고    scopus 로고
    • Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcrip-tional upregulation by cytokines
    • Seliger B, Schreiber K, Delp K, et al. Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcrip-tional upregulation by cytokines. Tissue Antigens. 2001;57(1):39-45.
    • (2001) Tissue Antigens. , vol.57 , Issue.1 , pp. 39-45
    • Seliger, B.1    Schreiber, K.2    Delp, K.3
  • 144
    • 78049500153 scopus 로고    scopus 로고
    • Downregulation of tapasin expression in primary human oral squamous cell carcinoma: Association with clinical outcome
    • Jiang Q, Pan HY, Ye DX, Zhang P, Zhong L P, Zhang ZY. Downregulation of tapasin expression in primary human oral squamous cell carcinoma: association with clinical outcome. Tumour Biol. 2010;31(5):451-459.
    • (2010) Tumour Biol. , vol.31 , Issue.5 , pp. 451-459
    • Jiang, Q.1    Pan, H.Y.2    Ye, D.X.3    Zhang, P.4    Zhong, L.P.5    Zhang, Z.Y.6
  • 145
    • 50349084447 scopus 로고    scopus 로고
    • HLA class i antigen processing machinery component expression and intratumoral T-Cell infiltrate as independent prognostic markers in ovarian carcinoma
    • Han LY, Fletcher MS, Urbauer DL, et al. HLA class I antigen processing machinery component expression and intratumoral T-Cell infiltrate as independent prognostic markers in ovarian carcinoma. Clin Cancer Res. 2008;14(11):3372- 3379.
    • (2008) Clin Cancer Res. , vol.14 , Issue.11 , pp. 3372-3379
    • Han, L.Y.1    Fletcher, M.S.2    Urbauer, D.L.3
  • 146
    • 33845494066 scopus 로고    scopus 로고
    • Expression and prognostic significance of prothymosin-alpha and ERp57 in human gastric cancer
    • Leys CM, Nomura S, LaFleur BJ, et al. Expression and prognostic significance of prothymosin-alpha and ERp57 in human gastric cancer. Surgery. 2007;141(1):41-50.
    • (2007) Surgery. , vol.141 , Issue.1 , pp. 41-50
    • Leys, C.M.1    Nomura, S.2    Lafleur, B.J.3
  • 147
    • 77957256424 scopus 로고    scopus 로고
    • Identification of E2F1 as an important transcription factor for the regulation of tapasin expression
    • Bukur J, Herrmann F, Handke D, Recktenwald C, Seliger B. Identification of E2F1 as an important transcription factor for the regulation of tapasin expression. J Biol Chem. 2010;285(40):30419-30426.
    • (2010) J Biol Chem. , vol.285 , Issue.40 , pp. 30419-30426
    • Bukur, J.1    Herrmann, F.2    Handke, D.3    Recktenwald, C.4    Seliger, B.5
  • 148
    • 0032952358 scopus 로고    scopus 로고
    • Soluble HLA in human body fluids
    • Aultman D, Adamashvili I, Yaturu K, et al. Soluble HLA in human body fluids. Hum Immunol. 1999;60(3):239-244.
    • (1999) Hum Immunol. , vol.60 , Issue.3 , pp. 239-244
    • Aultman, D.1    Adamashvili, I.2    Yaturu, K.3
  • 149
    • 0028897430 scopus 로고
    • Serum HLA class i antigens: Markers and modulators of an immune response?
    • Puppo F, Scudeletti M, Indiveri F, Ferrone S. Serum HLA class I antigens: markers and modulators of an immune response? Immunol Today. 1995;16(3):124-127.
    • (1995) Immunol Today. , vol.16 , Issue.3 , pp. 124-127
    • Puppo, F.1    Scudeletti, M.2    Indiveri, F.3    Ferrone, S.4
  • 151
    • 33845225727 scopus 로고    scopus 로고
    • Soluble HLA revisited
    • Tabayoyong WB, Zavazava N. Soluble HLA revisited. Leuk Res. 2007;31(2):121-125.
    • (2007) Leuk Res. , vol.31 , Issue.2 , pp. 121-125
    • Tabayoyong, W.B.1    Zavazava, N.2
  • 152
    • 0022491327 scopus 로고
    • Secretion of HLA-A and-B antigens via an alternative RNA splicing pathway
    • Krangel MS. Secretion of HLA-A and-B antigens via an alternative RNA splicing pathway. J Exp Med. 1986;163(5):1173-1190.
    • (1986) J Exp Med. , vol.163 , Issue.5 , pp. 1173-1190
    • Krangel, M.S.1
  • 153
    • 0028181764 scopus 로고
    • Soluble beta 2-microglob-ulin-free class i heavy chains are released from the surface of activated and leukemia cells by a metalloprotease
    • Demaria S, Schwab R, Gottesman SR, Bushkin Y. Soluble beta 2-microglob-ulin-free class I heavy chains are released from the surface of activated and leukemia cells by a metalloprotease. J Biol Chem. 1994;269(9):6689-6694.
    • (1994) J Biol Chem. , vol.269 , Issue.9 , pp. 6689-6694
    • Demaria, S.1    Schwab, R.2    Gottesman, S.R.3    Bushkin, Y.4
  • 154
    • 0034489808 scopus 로고    scopus 로고
    • Soluble HLA proteins with bound peptides are released from the cell surface by the membrane metalloproteinase
    • Demaria S, Bushkin Y. Soluble HLA proteins with bound peptides are released from the cell surface by the membrane metalloproteinase. Hum Immunol. 2000;61(12):1332-1338.
    • (2000) Hum Immunol. , vol.61 , Issue.12 , pp. 1332-1338
    • Demaria, S.1    Bushkin, Y.2
  • 155
    • 33845208244 scopus 로고    scopus 로고
    • Clinical relevance of soluble HLA-I and beta2-microglobulin levels in non-Hodgkin's lymphoma and Hodgkin's disease
    • Albitar M, Vose JM, Johnson MM, et al. Clinical relevance of soluble HLA-I and beta2-microglobulin levels in non-Hodgkin's lymphoma and Hodgkin's disease. Leuk Res. 2007;31(2):139-145.
    • (2007) Leuk Res. , vol.31 , Issue.2 , pp. 139-145
    • Albitar, M.1    Vose, J.M.2    Johnson, M.M.3
  • 156
    • 33747610000 scopus 로고    scopus 로고
    • Antigen presentation machinery (APM) modulation and soluble HLA molecules in the tumor microenvironment: Do they provide tumor cells with escape mechanisms from recognition by cytotoxic T lymphocytes?
    • Bangia N, Ferrone S. Antigen presentation machinery (APM) modulation and soluble HLA molecules in the tumor microenvironment: do they provide tumor cells with escape mechanisms from recognition by cytotoxic T lymphocytes? Immunol Invest. 2006;35(3-4):485-503.
    • (2006) Immunol Invest. , vol.35 , Issue.3-4 , pp. 485-503
    • Bangia, N.1    Ferrone, S.2
  • 158
    • 0032883578 scopus 로고    scopus 로고
    • Increased serum levels of beta2m-free HLA class i heavy chain in multiple myeloma
    • Perosa F, Luccarelli G, Prete M, Ferrone S, Dammacco F. Increased serum levels of beta2m-free HLA class I heavy chain in multiple myeloma. Br J Haematol. 1999;106(4):987-994.
    • (1999) Br J Haematol. , vol.106 , Issue.4 , pp. 987-994
    • Perosa, F.1    Luccarelli, G.2    Prete, M.3    Ferrone, S.4    Dammacco, F.5
  • 159
    • 0037220038 scopus 로고    scopus 로고
    • Size variants of beta-2-mi-croglobulin-free human leucocyte antigen class i heavy chain make different contributions to its serum increase in multiple myeloma
    • Perosa F, Prete M, Luccarelli G, Dammacco F. Size variants of beta-2-mi-croglobulin-free human leucocyte antigen class I heavy chain make different contributions to its serum increase in multiple myeloma. Br J Haematol. 2003;120(1):36-43.
    • (2003) Br J Haematol. , vol.120 , Issue.1 , pp. 36-43
    • Perosa, F.1    Prete, M.2    Luccarelli, G.3    Dammacco, F.4
  • 161
    • 0034788243 scopus 로고    scopus 로고
    • MHC antigens and tumor escape from immune surveillance
    • Garrido F, Algarra I. MHC antigens and tumor escape from immune surveillance. Adv Cancer Res. 2001;83:117-158.
    • (2001) Adv Cancer Res. , vol.83 , pp. 117-158
    • Garrido, F.1    Algarra, I.2
  • 162
    • 0030449845 scopus 로고    scopus 로고
    • Selection for beta 2-microglobulin mutation in mismatch repair-defective colorectal carcinomas
    • Bicknell DC, Kaklamanis L, Hampson R, Bodmer WF, Karran P. Selection for beta 2-microglobulin mutation in mismatch repair-defective colorectal carcinomas. Curr Biol. 1996;6(12):1695-1697.
    • (1996) Curr Biol. , vol.6 , Issue.12 , pp. 1695-1697
    • Bicknell, D.C.1    Kaklamanis, L.2    Hampson, R.3    Bodmer, W.F.4    Karran, P.5
  • 163
    • 0031856709 scopus 로고    scopus 로고
    • High frequency of altered HLA class i phenotypes in invasive colorectal carcinomas
    • Cabrera T, Collado A, Fernandez MA, et al. High frequency of altered HLA class I phenotypes in invasive colorectal carcinomas. Tissue Antigens. 1998;52(2):114-123.
    • (1998) Tissue Antigens. , vol.52 , Issue.2 , pp. 114-123
    • Cabrera, T.1    Collado, A.2    Fernandez, M.A.3
  • 164
    • 34247263417 scopus 로고    scopus 로고
    • Analysis of HLA class i alterations in tumors: Choosing a strategy based on known patterns of underlying molecular mechanisms
    • Cabrera T, Maleno I, Collado A, Lopez Nevot MA, Tait BD, Garrido F. Analysis of HLA class I alterations in tumors: choosing a strategy based on known patterns of underlying molecular mechanisms. Tissue Antigens. 2007;69(Suppl 1):264-268.
    • (2007) Tissue Antigens. , vol.69 , Issue.SUPPL. 1 , pp. 264-268
    • Cabrera, T.1    Maleno, I.2    Collado, A.3    Lopez Nevot, M.A.4    Tait, B.D.5    Garrido, F.6
  • 165
    • 0033038815 scopus 로고    scopus 로고
    • Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features
    • Yamamoto H, Perez-Piteira J, Yoshida T, et al. Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features. Gastroenterology. 1999;116(6):1348-1357.
    • (1999) Gastroenterology. , vol.116 , Issue.6 , pp. 1348-1357
    • Yamamoto, H.1    Perez-Piteira, J.2    Yoshida, T.3
  • 166
    • 0032217242 scopus 로고    scopus 로고
    • Mutations of the beta2-microglobulin gene result in a lack of HLA class i molecules on melanoma cells of two patients immunized with MAGE peptides
    • Benitez R, Godelaine D, Lopez-Nevot MA, et al. Mutations of the beta2-microglobulin gene result in a lack of HLA class I molecules on melanoma cells of two patients immunized with MAGE peptides. Tissue Antigens. 1998;52(6):520-529.
    • (1998) Tissue Antigens. , vol.52 , Issue.6 , pp. 520-529
    • Benitez, R.1    Godelaine, D.2    Lopez-Nevot, M.A.3
  • 167
    • 0032525339 scopus 로고    scopus 로고
    • Beta2-Microglobulin mutations, HLA class i antigen loss, and tumor progression in melanoma
    • Hicklin DJ, Wang Z, Arienti F, Rivoltini L, Parmiani G, Ferrone S. beta2-Microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma. J Clin Invest. 1998;101(12):2720-2729.
    • (1998) J Clin Invest. , vol.101 , Issue.12 , pp. 2720-2729
    • Hicklin, D.J.1    Wang, Z.2    Arienti, F.3    Rivoltini, L.4    Parmiani, G.5
  • 168
    • 0035886022 scopus 로고    scopus 로고
    • Rexpression of HLA class i antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2'-deoxycytidine treatment
    • Serrano A, Tanzarella S, Lionello I, et al. Rexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2'-deoxycytidine treatment. Int J Cancer. 2001;94(2):243-251.
    • (2001) Int J Cancer. , vol.94 , Issue.2 , pp. 243-251
    • Serrano, A.1    Tanzarella, S.2    Lionello, I.3
  • 169
    • 0032498555 scopus 로고    scopus 로고
    • Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells
    • White CA, Thomson SA, Cooper L, et al. Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells. Int J Cancer. 1998;75(4):590-595.
    • (1998) Int J Cancer. , vol.75 , Issue.4 , pp. 590-595
    • White, C.A.1    Thomson, S.A.2    Cooper, L.3
  • 170
    • 67650070302 scopus 로고    scopus 로고
    • Downregulation of HLA class i molecules in primary oral squamous cell carcinomas and cell lines
    • Tang Q, Zhang J, Qi B, Shen C, Xie W. Downregulation of HLA class I molecules in primary oral squamous cell carcinomas and cell lines. Arch Med Res. 2009;40(4):256-263.
    • (2009) Arch Med Res. , vol.40 , Issue.4 , pp. 256-263
    • Tang, Q.1    Zhang, J.2    Qi, B.3    Shen, C.4    Xie, W.5
  • 171
    • 0036038734 scopus 로고    scopus 로고
    • Multiple mechanisms generate HLA class i altered phenotypes in laryngeal carcinomas: High frequency of HLA haplotype loss associated with loss of heterozygosity in chromosome region 6p21
    • Maleno I, Lopez-Nevot MA, Cabrera T, Salinero J, Garrido F. Multiple mechanisms generate HLA class I altered phenotypes in laryngeal carcinomas: high frequency of HLA haplotype loss associated with loss of heterozygosity in chromosome region 6p21. Cancer Immunol Immunother. 2002;51(7):389-396.
    • (2002) Cancer Immunol Immunother. , vol.51 , Issue.7 , pp. 389-396
    • Maleno, I.1    Lopez-Nevot, M.A.2    Cabrera, T.3    Salinero, J.4    Garrido, F.5
  • 172
    • 0030272636 scopus 로고    scopus 로고
    • High frequency of altered HLA class i phenotypes in invasive breast carcinomas
    • Cabrera T, Angustias FM, Sierra A, et al. High frequency of altered HLA class I phenotypes in invasive breast carcinomas. Hum Immunol. 1996;50(2):127-134.
    • (1996) Hum Immunol. , vol.50 , Issue.2 , pp. 127-134
    • Cabrera, T.1    Angustias, F.M.2    Sierra, A.3
  • 173
    • 0031080901 scopus 로고    scopus 로고
    • Implications for immunosur-veillance of altered HLA class i phenotypes in human tumours
    • Garrido F, Ruiz-Cabello F, Cabrera T, et al. Implications for immunosur-veillance of altered HLA class I phenotypes in human tumours. Immunol Today. 1997;18(2):89-95.
    • (1997) Immunol Today. , vol.18 , Issue.2 , pp. 89-95
    • Garrido, F.1    Ruiz-Cabello, F.2    Cabrera, T.3
  • 174
    • 0026697732 scopus 로고
    • Locus-specific transcriptional control of HLA genes
    • Soong TW, Hui KM. Locus-specific transcriptional control of HLA genes. J Immunol. 1992;149(6):2008-2020.
    • (1992) J Immunol. , vol.149 , Issue.6 , pp. 2008-2020
    • Soong, T.W.1    Hui, K.M.2
  • 175
    • 0026039901 scopus 로고
    • Regulation of the expression of major histocompat-ibility complex class i genes in human colorectal cancer
    • Soong TW, Hui KM. Regulation of the expression of major histocompat-ibility complex class I genes in human colorectal cancer. Cancer Detect Prev. 1991;15(3):231-239.
    • (1991) Cancer Detect Prev. , vol.15 , Issue.3 , pp. 231-239
    • Soong, T.W.1    Hui, K.M.2
  • 177
    • 0034433470 scopus 로고    scopus 로고
    • HLA-B locus-specific downregulation in human melanoma requires enhancer A as well as a sequence element located downstream of the transcription initiation site
    • Griffioen M, Ouwerkerk IJ, Harten V, Schrier PI. HLA-B locus-specific downregulation in human melanoma requires enhancer A as well as a sequence element located downstream of the transcription initiation site. Immunogenetics. 2000;52(1-2):121-128.
    • (2000) Immunogenetics. , vol.52 , Issue.1-2 , pp. 121-128
    • Griffioen, M.1    Ouwerkerk, I.J.2    Harten, V.3    Schrier, P.I.4
  • 178
    • 0037050214 scopus 로고    scopus 로고
    • Down-regulation of MHC class i by bovine papillomavirus E5 oncoproteins
    • Ashrafi GH, Tsirimonaki E, Marchetti B, et al. Down-regulation of MHC class I by bovine papillomavirus E5 oncoproteins. Oncogene. 2002;21(2):248-259.
    • (2002) Oncogene. , vol.21 , Issue.2 , pp. 248-259
    • Ashrafi, G.H.1    Tsirimonaki, E.2    Marchetti, B.3
  • 179
    • 0029095658 scopus 로고
    • C-myc represses transiently transfected HLA class i promoter sequences not locus-specifically
    • Griffioen M, Peltenburg LT, van Oorschot DA, Schrier PI. C-myc represses transiently transfected HLA class I promoter sequences not locus-specifically. Immunobiology. 1995;193(2-4):238-47.
    • (1995) Immunobiology. , vol.193 , Issue.2-4 , pp. 238-247
    • Griffioen, M.1    Peltenburg, L.T.2    Van Oorschot, D.A.3    Schrier, P.I.4
  • 180
    • 1642535582 scopus 로고    scopus 로고
    • HER-2/neu-mediated regulation of components of the MHC class i antigen-processing pathway
    • Herrmann F, Lehr HA, Drexler I, et al. HER-2/neu-mediated regulation of components of the MHC class I antigen-processing pathway. Cancer Res. 2004;64(1):215-220.
    • (2004) Cancer Res. , vol.64 , Issue.1 , pp. 215-220
    • Herrmann, F.1    Lehr, H.A.2    Drexler, I.3
  • 181
    • 0031964480 scopus 로고    scopus 로고
    • Down-regulation of the MHC class i antigen-processing machinery after oncogenic transformation of murine fibroblasts
    • Seliger B, Harders C, Lohmann S, et al. Down-regulation of the MHC class I antigen-processing machinery after oncogenic transformation of murine fibroblasts. Eur J Immunol. 1998;28(1):122-133.
    • (1998) Eur J Immunol. , vol.28 , Issue.1 , pp. 122-133
    • Seliger, B.1    Harders, C.2    Lohmann, S.3
  • 182
    • 0037414796 scopus 로고    scopus 로고
    • Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5-versus type 12-transformed cells
    • Vertegaal AC, Kuiperij HB, Houweling A, Verlaan M, van der Eb AJ, Zantema A. Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5-versus type 12-transformed cells. J Biol Chem. 2003;278(1):139-46.
    • (2003) J Biol Chem. , vol.278 , Issue.1 , pp. 139-146
    • Vertegaal, A.C.1    Kuiperij, H.B.2    Houweling, A.3    Verlaan, M.4    Van Der Eb, A.J.5    Zantema, A.6
  • 183
    • 50649087258 scopus 로고    scopus 로고
    • Molecular mechanisms of MHC class i abnormalities and APM components in human tumors
    • Seliger B. Molecular mechanisms of MHC class I abnormalities and APM components in human tumors. Cancer Immunol Immunother. 2008;57(11):1719-1726.
    • (2008) Cancer Immunol Immunother. , vol.57 , Issue.11 , pp. 1719-1726
    • Seliger, B.1
  • 184
    • 0034123984 scopus 로고    scopus 로고
    • Microsatellite analysis of microdissected tumor cells and 6p high density microsatellite analysis in head and neck squamous cell carcinomas with down-regulated human leukocyte antigen class i expression
    • Feenstra M, Verdaasdonk M, van der Zwan AW, de WR, Slootweg P, Tilanus M. Microsatellite analysis of microdissected tumor cells and 6p high density microsatellite analysis in head and neck squamous cell carcinomas with down-regulated human leukocyte antigen class I expression. Lab Invest. 2000;80(3):405-414.
    • (2000) Lab Invest. , vol.80 , Issue.3 , pp. 405-414
    • Feenstra, M.1    Verdaasdonk, M.2    Van Der Zwan, A.W.3    De Wr Slootweg, P.4    Tilanus, M.5
  • 185
    • 0029936243 scopus 로고    scopus 로고
    • Loss of an HLA haplotype in pancreas cancer tissue and its corresponding tumor derived cell line
    • Torres MJ, Ruiz-Cabello F, Skoudy A, et al. Loss of an HLA haplotype in pancreas cancer tissue and its corresponding tumor derived cell line. Tissue Antigens. 1996;47(5):372-381.
    • (1996) Tissue Antigens. , vol.47 , Issue.5 , pp. 372-381
    • Torres, M.J.1    Ruiz-Cabello, F.2    Skoudy, A.3
  • 186
    • 0028088595 scopus 로고
    • Quantification of serum-soluble HLA class i antigens in patients with gastric cancer
    • Shimura T, Hagihara M, Yamamoto K, et al. Quantification of serum-soluble HLA class I antigens in patients with gastric cancer. Hum Immunol. 1994;40(3):183-186.
    • (1994) Hum Immunol. , vol.40 , Issue.3 , pp. 183-186
    • Shimura, T.1    Hagihara, M.2    Yamamoto, K.3
  • 187
    • 0031701902 scopus 로고    scopus 로고
    • Soluble HLA class i antigens in plasma of patients with malignant melanoma
    • Westhoff U, Fox C, Otto FJ. Soluble HLA class I antigens in plasma of patients with malignant melanoma. Anticancer Res. 1998;18(5B):3789-3792.
    • (1998) Anticancer Res. , vol.18 , Issue.5 B , pp. 3789-3792
    • Westhoff, U.1    Fox, C.2    Otto, F.J.3
  • 188
    • 0034985433 scopus 로고    scopus 로고
    • Clinical significance of soluble form of HLA class i molecule in Japanese patients with pancreatic cancer
    • Shimura T, Tsutsumi S, Hosouchi Y, et al. Clinical significance of soluble form of HLA class I molecule in Japanese patients with pancreatic cancer. Hum Immunol. 2001;62(6):615-619.
    • (2001) Hum Immunol. , vol.62 , Issue.6 , pp. 615-619
    • Shimura, T.1    Tsutsumi, S.2    Hosouchi, Y.3
  • 189
    • 19944428928 scopus 로고    scopus 로고
    • HLA class i NKG2D and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells
    • Carbone E, Neri P, Mesuraca M, et al. HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells. Blood. 2005;105(1):251-258.
    • (2005) Blood. , vol.105 , Issue.1 , pp. 251-258
    • Carbone, E.1    Neri, P.2    Mesuraca, M.3
  • 190
    • 27144464502 scopus 로고    scopus 로고
    • Total soluble HLA class i and soluble HLA-G in multiple myeloma and monoclonal gammopathy of undetermined significance
    • Leleu X, Le FG, Facon T, et al. Total soluble HLA class I and soluble HLA-G in multiple myeloma and monoclonal gammopathy of undetermined significance. Clin Cancer Res. 2005;11(20):7297-7303.
    • (2005) Clin Cancer Res. , vol.11 , Issue.20 , pp. 7297-7303
    • Leleu, X.1    Le, F.G.2    Facon, T.3
  • 191
    • 33745714225 scopus 로고    scopus 로고
    • Association of antigen-processing machinery and HLA antigen phenotype of melanoma cells with survival in American Joint Committee on Cancer stage III and IV melanoma patients
    • Anichini A, Mortarini R, Nonaka D, et al. Association of antigen-processing machinery and HLA antigen phenotype of melanoma cells with survival in American Joint Committee on Cancer stage III and IV melanoma patients. Cancer Res. 2006;66(12):6405-6411.
    • (2006) Cancer Res. , vol.66 , Issue.12 , pp. 6405-6411
    • Anichini, A.1    Mortarini, R.2    Nonaka, D.3
  • 192
    • 33745714227 scopus 로고    scopus 로고
    • Frequent loss of HLA-A2 expression in metastasizing ovarian carcinomas associated with genomic haplo-type loss and HLA-A2-restricted HER-2/neu-specific immunity
    • Norell H, Carlsten M, Ohlum T, et al. Frequent loss of HLA-A2 expression in metastasizing ovarian carcinomas associated with genomic haplo-type loss and HLA-A2-restricted HER-2/neu-specific immunity. Cancer Res. 2006;66(12):6387- 6394.
    • (2006) Cancer Res. , vol.66 , Issue.12 , pp. 6387-6394
    • Norell, H.1    Carlsten, M.2    Ohlum, T.3
  • 193
    • 0027468145 scopus 로고
    • The biochemistry and cell biology of antigen processing and presentation
    • Germain RN, Margulies DH. The biochemistry and cell biology of antigen processing and presentation. Annu Rev Immunol. 1993;11:403-450.
    • (1993) Annu Rev Immunol. , vol.11 , pp. 403-450
    • Germain, R.N.1    Margulies, D.H.2
  • 194
    • 33749642346 scopus 로고    scopus 로고
    • Description of HLA class I-and CD8-deficient patients: Insights into the function of cytotoxic T lymphocytes and NK cells in host defense
    • Cerundolo V, de la SH. Description of HLA class I-and CD8-deficient patients: Insights into the function of cytotoxic T lymphocytes and NK cells in host defense. Semin Immunol. 2006;18(6):330-336.
    • (2006) Semin Immunol. , vol.18 , Issue.6 , pp. 330-336
    • Cerundolo, V.1    De La, S.H.2
  • 195
    • 84855912630 scopus 로고    scopus 로고
    • Bare lymphocyte syndrome: An opportunity to discover our immune system
    • Shrestha D, Szollosi J, Jenei A. Bare lymphocyte syndrome: an opportunity to discover our immune system. Immunol Lett. 2012;141(2):147-157.
    • (2012) Immunol Lett. , vol.141 , Issue.2 , pp. 147-157
    • Shrestha, D.1    Szollosi, J.2    Jenei, A.3
  • 197
    • 0031569976 scopus 로고    scopus 로고
    • Human peptide transporter deficiency: Importance of HLA-B in the presentation of TAP-independent EBV antigens
    • de la SH, Houssaint E, Peyrat MA, et al. Human peptide transporter deficiency: importance of HLA-B in the presentation of TAP-independent EBV antigens. J Immunol. 1997;158(10):4555-4563.
    • (1997) J Immunol. , vol.158 , Issue.10 , pp. 4555-4563
    • De La, S.H.1    Houssaint, E.2    Peyrat, M.A.3
  • 198
    • 0032514689 scopus 로고    scopus 로고
    • Major histocompatibility complex (MHC) class i KbDb-/-deficient mice possess functional CD8+ T cells and natural killer cells
    • Vugmeyster Y, Glas R, Perarnau B, Lemonnier FA, Eisen H, Ploegh H. Major histocompatibility complex (MHC) class I KbDb-/-deficient mice possess functional CD8+ T cells and natural killer cells. Proc Natl Acad Sci USA. 1998;95(21):12492-12497.
    • (1998) Proc Natl Acad Sci USA. , vol.95 , Issue.21 , pp. 12492-12497
    • Vugmeyster, Y.1    Glas, R.2    Perarnau, B.3    Lemonnier, F.A.4    Eisen, H.5    Ploegh, H.6
  • 199
    • 0031974121 scopus 로고    scopus 로고
    • Activity and phenotype of natural killer cells in peptide transporter (TAP)-deficient patients (type i bare lymphocyte syndrome)
    • Zimmer J, Donato L, Hanau D, et al. Activity and phenotype of natural killer cells in peptide transporter (TAP)-deficient patients (type I bare lymphocyte syndrome). J Exp Med. 1998;187(1):117-122.
    • (1998) J Exp Med. , vol.187 , Issue.1 , pp. 117-122
    • Zimmer, J.1    Donato, L.2    Hanau, D.3
  • 200
    • 30044438884 scopus 로고    scopus 로고
    • Processing and presentation of tumor antigens and vaccination strategies
    • van der Bruggen P, van den Eynde BJ. Processing and presentation of tumor antigens and vaccination strategies. Curr Opin Immunol. 2006;18(1):98-104.
    • (2006) Curr Opin Immunol. , vol.18 , Issue.1 , pp. 98-104
    • Van Der Bruggen, P.1    Van Den Eynde, B.J.2
  • 201
    • 51649121390 scopus 로고    scopus 로고
    • Tumor escape mechanisms: Potential role of soluble HLA antigens and NK cells activating ligands
    • Campoli M, Ferrone S. Tumor escape mechanisms: potential role of soluble HLA antigens and NK cells activating ligands. Tissue Antigens. 2008;72(4):321-334.
    • (2008) Tissue Antigens. , vol.72 , Issue.4 , pp. 321-334
    • Campoli, M.1    Ferrone, S.2
  • 202
    • 0034486610 scopus 로고    scopus 로고
    • Soluble HLA class I/CD8 ligation triggers apoptosis in EBV-specific CD8+ cytotoxic T lymphocytes by Fas/Fas-ligand interaction
    • Contini P, Ghio M, Merlo A, et al. Soluble HLA class I/CD8 ligation triggers apoptosis in EBV-specific CD8+ cytotoxic T lymphocytes by Fas/Fas-ligand interaction. Hum Immunol. 2000;61(12):1347-1351.
    • (2000) Hum Immunol. , vol.61 , Issue.12 , pp. 1347-1351
    • Contini, P.1    Ghio, M.2    Merlo, A.3
  • 203
    • 0037261143 scopus 로고    scopus 로고
    • Soluble HLA-A,-B,-C and-G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation
    • Contini P, Ghio M, Poggi A, et al. Soluble HLA-A,-B,-C and-G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation. Eur J Immunol. 2003;33(1):125-134.
    • (2003) Eur J Immunol. , vol.33 , Issue.1 , pp. 125-134
    • Contini, P.1    Ghio, M.2    Poggi, A.3
  • 204
    • 0033953078 scopus 로고    scopus 로고
    • Soluble human MHC class i molecules induce soluble Fas ligand secretion and trigger apoptosis in activated CD8(+) Fas (CD95)(+) T lymphocytes
    • Puppo F, Contini P, Ghio M, et al. Soluble human MHC class I molecules induce soluble Fas ligand secretion and trigger apoptosis in activated CD8(+) Fas (CD95)(+) T lymphocytes. Int Immunol. 2000;12(2):195-203.
    • (2000) Int Immunol. , vol.12 , Issue.2 , pp. 195-203
    • Puppo, F.1    Contini, P.2    Ghio, M.3
  • 205
    • 0029838383 scopus 로고    scopus 로고
    • Soluble HLA class i molecules induce apoptosis in alloreactive cytotoxic T lymphocytes
    • Zavazava N, Kronke M. Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes. Nat Med. 1996;2(9):1005-1010.
    • (1996) Nat Med. , vol.2 , Issue.9 , pp. 1005-1010
    • Zavazava, N.1    Kronke, M.2
  • 206
    • 0037220792 scopus 로고    scopus 로고
    • In vivo augmentation of tumor-specific CTL responses by class I/peptide antigen complexes on microspheres (large multivalent immunogen)
    • Goldberg J, Shrikant P, Mescher M F. In vivo augmentation of tumor-specific CTL responses by class I/peptide antigen complexes on microspheres (large multivalent immunogen). J Immunol. 2003;170(1):228-235.
    • (2003) J Immunol. , vol.170 , Issue.1 , pp. 228-235
    • Goldberg, J.1    Shrikant, P.2    Mescher, M.F.3
  • 207
    • 0035451465 scopus 로고    scopus 로고
    • Antigen-specific blockade of T cells in vivo using dimeric MHC peptide
    • O'Herrin SM, Slansky JE, Tang Q, et al. Antigen-specific blockade of T cells in vivo using dimeric MHC peptide. J Immunol. 2001;167(5):2555-2560.
    • (2001) J Immunol. , vol.167 , Issue.5 , pp. 2555-2560
    • O'Herrin, S.M.1    Slansky, J.E.2    Tang, Q.3
  • 208
    • 0037093066 scopus 로고    scopus 로고
    • Defective expression and function of natural killer cell-triggering receptors in patients with acute mye-loid leukemia
    • Costello RT, Sivori S, Marcenaro E, et al. Defective expression and function of natural killer cell-triggering receptors in patients with acute mye-loid leukemia. Blood. 2002;99(10):3661-3667.
    • (2002) Blood. , vol.99 , Issue.10 , pp. 3661-3667
    • Costello, R.T.1    Sivori, S.2    Marcenaro, E.3
  • 209
    • 0029823977 scopus 로고    scopus 로고
    • CD56+bright and CD56+dim natural killer cells in patients with chronic myelogenous leukemia progressively decrease in number, respond less to stimuli that recruit clonogenic natural killer cells, and exhibit decreased proliferation on a per cell basis
    • Pierson BA, Miller JS. CD56+bright and CD56+dim natural killer cells in patients with chronic myelogenous leukemia progressively decrease in number, respond less to stimuli that recruit clonogenic natural killer cells, and exhibit decreased proliferation on a per cell basis. Blood. 1996;88(6):2279- 2287.
    • (1996) Blood. , vol.88 , Issue.6 , pp. 2279-2287
    • Pierson, B.A.1    Miller, J.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.