SCOPUS 정보 검색 플랫폼

Volumn 3, Issue 11, 2014, Pages e970027-1-e970027-3

Chimeric antigen receptor T cells are vulnerable to immunosuppressive mechanisms present within the tumor microenvironment

(2) Beatty, Gregory L a Moon, Edmund K b

a UNIVERSITY OF PENNSYLVANIA (United States)

b UNIVERSITY OF PENNSYLVANIA (United States)

Author keywords

adoptive cell therapy; cancer; chimeric antigen receptor T cells; immune checkpoint molecules; tumor microenvironment

Indexed keywords

CD137 ANTIGEN; CD19 ANTIGEN; CD28 ANTIGEN; CELL THERAPY AGENT; CHIMERIC ANTIGEN RECEPTOR; MESOTHELIN; PROGRAMMED DEATH 1 RECEPTOR;

ARTICLE; CANCER THERAPY; CELL SURVIVAL; FIBROBLAST; HEMATOLOGIC MALIGNANCY; HUMAN; IMMUNE DEFICIENCY; LEUKOCYTE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MESOTHELIOMA; PANCREAS CARCINOMA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOLID TUMOR; T LYMPHOCYTE; TUMOR ESCAPE; TUMOR GROWTH; TUMOR MICROENVIRONMENT;

EID: 84938600031 PISSN: 21624011 EISSN: 2162402X Source Type: Journal
DOI: 10.4161/21624011.2014.970027 Document Type: Article

Times cited : (63)

References (6)

1
- 84877669593
- The basic principles of chimeric antigen receptor design
- 23550147
- M.Sadelain, R.Brentjens, I.Riviere. The basic principles of chimeric antigen receptor design. Cancer Discov 2013; 3:388-98; PMID:23550147; http://dx.doi.org/10.1158/2159-8290.CD-12-0548
- (2013) Cancer Discov , vol.3 , pp. 388-398
- Sadelain, M.¹ Brentjens, R.² Riviere, I.³

2
- 84996572349
- Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce antitumor activity in solid malignancies
- 24579088
- G.L.Beatty, A.R.Haas, M.V.Maus, D.A.Torigian, M.C.Soulen, G.Plesa, A.Chew, Y.Zhao, B.L.Levine, S.M.Albelda Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce antitumor activity in solid malignancies. Cancer Immunol Res 2014; 2:112-20; PMID:24579088; http://dx.doi.org/10.1158/2326-6066.CIR-13-0170
- (2014) Cancer Immunol Res , vol.2 , pp. 112-120
- Beatty, G.L.¹ Haas, A.R.² Maus, M.V.³ Torigian, D.A.⁴ Soulen, M.C.⁵ Plesa, G.⁶ Chew, A.⁷ Zhao, Y.⁸ Levine, B.L.⁹ Albelda, S.M.¹⁰

3
- 84902124061
- Discovery of mesothelin and exploiting it as a target for immunotherapy
- 24824231
- I.Pastan, R.Hassan. Discovery of mesothelin and exploiting it as a target for immunotherapy. Cancer Res 2014; 74:2907-12; PMID:24824231; http://dx.doi.org/10.1158/0008-5472.CAN-14-0337
- (2014) Cancer Res , vol.74 , pp. 2907-2912
- Pastan, I.¹ Hassan, R.²

4
- 84905993539
- Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors
- 24919573
- E.K.Moon, L.C.Wang, D.V.Dolfi, C.B.Wilson, R.Ranganathan, J.Sun, V.Kapoor, J.Scholler, E.Pure, M.C.Milone Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors. Clin Cancer Res 2014; 20:4262-73; PMID:24919573; http://dx.doi.org/10.1158/1078-0432.CCR-13-2627
- (2014) Clin Cancer Res , vol.20 , pp. 4262-4273
- Moon, E.K.¹ Wang, L.C.² Dolfi, D.V.³ Wilson, C.B.⁴ Ranganathan, R.⁵ Sun, J.⁶ Kapoor, V.⁷ Scholler, J.⁸ Pure, E.⁹ Milone, M.C.¹⁰

5
- 62549097817
- Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
- 19211796
- C.Carpenito, M.C.Milone, R.Hassan, J.C.Simonet, M.Lakhal, M.M.Suhoski, A.Varela-Rohena, K.M.Haines, D.F.Heitjan, S.M.Albelda Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains. Proc Natl Acad Sci U S A 2009; 106:3360-5; PMID:19211796; http://dx.doi.org/10.1073/pnas.0813101106
- (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3360-3365
- Carpenito, C.¹ Milone, M.C.² Hassan, R.³ Simonet, J.C.⁴ Lakhal, M.⁵ Suhoski, M.M.⁶ Varela-Rohena, A.⁷ Haines, K.M.⁸ Heitjan, D.F.⁹ Albelda, S.M.¹⁰

6
- 78549253550
- Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor
- 20926399
- Y.Zhao, E.Moon, C.Carpenito, C.M.Paulos, X.Liu, A.L.Brennan, A.Chew, R.G.Carroll, J.Scholler, B.L.Levine Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor. Cancer Res 2010; 70:9053-61; PMID:20926399; http://dx.doi.org/10.1158/0008-5472.CAN-10-2880
- (2010) Cancer Res , vol.70 , pp. 9053-9061
- Zhao, Y.¹ Moon, E.² Carpenito, C.³ Paulos, C.M.⁴ Liu, X.⁵ Brennan, A.L.⁶ Chew, A.⁷ Carroll, R.G.⁸ Scholler, J.⁹ Levine, B.L.¹⁰

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.