A bispecific chimeric antigen receptor molecule enhances T cell activation through dual immunological synapse formation and offsets antigen escape in glioblastoma

Journal for ImmunoTherapy of Cancer

Volumn 3, Issue , 2015, Pages

  Hegde, Meenakshi ^a   Grada, Zakaria ^a   Pignata, Antonella ^a   Wakefield, Amanda ^a   Fousek, Kristen ^a   Bielamowicz, Kevin ^a   Chow, Kevin ^a   Brawley, Vita ^a   Byrd, Tiara ^a   Gottschalk, Stephen ^a   Mukherjee, Malini ^a   Wels, Winfried S ^b   Baker, Matthew ^a   Dotti, Giapietro ^a   Orange, Jordan ^a   Ahmed, Nabil ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC ANTIGEN RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GAMMA INTERFERON; INTERLEUKIN 2;

ARTICLE; CANCER GROWTH; COMPUTER MODEL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMAGE RECONSTRUCTION; IMMUNOFLUORESCENCE TEST; IMMUNOLOGICAL SYNAPSE; PHASE 1 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STATISTICAL MODEL; T LYMPHOCYTE ACTIVATION; TUMOR RECURRENCE; UPN1 CELL LINE;

EID: 85020151037     PISSN: None     EISSN: 20511426     Source Type: Journal    
DOI: 10.1186/2051-1426-3-S2-O3     Document Type: Article

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