메뉴 건너뛰기




Volumn 22, Issue 2, 2015, Pages 95-100

Manufacture of T cells using the Sleeping Beauty system to enforce expression of a CD19-specific chimeric antigen receptor

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR; RETROPOSON;

EID: 84924804013     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2014.69     Document Type: Review
Times cited : (69)

References (55)
  • 1
    • 77949424429 scopus 로고    scopus 로고
    • Progress and prospects: Immune responses to viral vectors
    • Nayak S, Herzog RW. Progress and prospects: immune responses to viral vectors. Gene Therapy 2010; 17: 295-304.
    • (2010) Gene Therapy , vol.17 , pp. 295-304
    • Nayak, S.1    Herzog, R.W.2
  • 2
    • 84924790033 scopus 로고    scopus 로고
    • DNA plasmids for non-viral gene therapy of cancer
    • Brenner MK, Hung M-C (eds). John Wiley & Sons
    • Najjar AM, Moyes JS, Cooper LJN. DNA plasmids for non-viral gene therapy of cancer. In: Brenner MK, Hung M-C (eds) Cancer Gene Therapy by Viral and Non- Viral Vectors. John Wiley & Sons, 2014 pp 39-59.
    • (2014) Cancer Gene Therapy by Viral and Non- Viral Vectors , pp. 39-59
    • Najjar, A.M.1    Moyes, J.S.2    Ljn, C.3
  • 4
    • 17644425657 scopus 로고    scopus 로고
    • A direct comparison of two nonviral gene therapy vectors for somatic integration: In vivo evaluation of the bacteriophage integrase phic31 and the sleeping beauty transposase
    • Ehrhardt A, Xu H, Huang Z, Engler JA, Kay MA. A direct comparison of two nonviral gene therapy vectors for somatic integration: in vivo evaluation of the bacteriophage integrase phiC31 and the Sleeping Beauty transposase. Mol Ther 2005; 11: 695-706.
    • (2005) Mol Ther , vol.11 , pp. 695-706
    • Ehrhardt, A.1    Xu, H.2    Huang, Z.3    Engler, J.A.4    Kay, M.A.5
  • 5
    • 38449110499 scopus 로고    scopus 로고
    • Tol2: A versatile gene transfer vector in vertebrates
    • Kawakami K. Tol2: a versatile gene transfer vector in vertebrates. Genome Biol 2007; 8: S7.
    • (2007) Genome Biol , vol.8 , pp. S7
    • Kawakami, K.1
  • 6
    • 33750060436 scopus 로고    scopus 로고
    • PiggyBac is a flexible and highly active transposon as compared to sleeping beauty tol2, and mos1 in mammalian cells
    • Wu SC, Meir YJ, Coates CJ, Handler AM, Pelczar P, Moisyadi S et al. piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells. Proc Natl Acad Sci USA 2006; 103: 15008-15013.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15008-15013
    • Wu, S.C.1    Meir, Y.J.2    Coates, C.J.3    Handler, A.M.4    Pelczar, P.5    Moisyadi, S.6
  • 7
    • 79955990614 scopus 로고    scopus 로고
    • The sleeping beauty transposon system: A non-viral vector for gene therapy
    • Aronovich EL, McIvor RS, Hackett PB. The Sleeping Beauty transposon system: a non-viral vector for gene therapy. Hum Mol Genet 2011; 20: R14-R20.
    • (2011) Hum Mol Genet , vol.20 , pp. R14-R20
    • Aronovich, E.L.1    McIvor, R.S.2    Hackett, P.B.3
  • 8
    • 77956668327 scopus 로고    scopus 로고
    • Translating sleeping beauty transposition into cellular therapies: Victories and challenges
    • Izsvak Z, Hackett PB, Cooper LJ, Ivics Z. Translating Sleeping Beauty transposition into cellular therapies: victories and challenges. Bioessays 2010; 32: 756-767.
    • (2010) Bioessays , vol.32 , pp. 756-767
    • Izsvak, Z.1    Hackett, P.B.2    Cooper, L.J.3    Ivics, Z.4
  • 9
    • 77950525914 scopus 로고    scopus 로고
    • A transposon and transposase system for human application
    • Hackett PB, Largaespada DA, Cooper LJ. A transposon and transposase system for human application. Mol Ther 2010; 18: 674-683.
    • (2010) Mol Ther , vol.18 , pp. 674-683
    • Hackett, P.B.1    Largaespada, D.A.2    Cooper, L.J.3
  • 10
    • 4744355872 scopus 로고    scopus 로고
    • Escape from immunotherapy: Possible mechanisms that influence tumor regression/progression
    • Ahmad M, Rees RC, Ali SA. Escape from immunotherapy: possible mechanisms that influence tumor regression/progression. Cancer Immunol Immunother 2004; 53: 844-854.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 844-854
    • Ahmad, M.1    Rees, R.C.2    Ali, S.A.3
  • 11
    • 70149114880 scopus 로고    scopus 로고
    • Gene therapy with human and mouse t-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
    • Johnson LA, Morgan RA, Dudley ME, Morgan RA, Dudley ME, Cassard L et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood 2009; 114: 535-546.
    • (2009) Blood , vol.114 , pp. 535-546
    • Johnson, L.A.1    Morgan, R.A.2    Dudley, M.E.3    Morgan, R.A.4    Dudley, M.E.5    Cassard, L.6
  • 12
    • 79952187823 scopus 로고    scopus 로고
    • T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
    • Parkhurst MR, Yang JC, Langan RC, Dudley ME, Nathan DA, Feldman SA et al. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Mol Ther 2011; 19: 620-626.
    • (2011) Mol Ther , vol.19 , pp. 620-626
    • Parkhurst, M.R.1    Yang, J.C.2    Langan, R.C.3    Dudley, M.E.4    Nathan, D.A.5    Feldman, S.A.6
  • 13
    • 79952304769 scopus 로고    scopus 로고
    • Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with ny-eso-1
    • Robbins PF, Morgan RA, Feldman SA, Yang JC, Sherry RM, Dudley ME et al. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1. J Clin Oncol 2011; 29: 917-924.
    • (2011) J Clin Oncol , vol.29 , pp. 917-924
    • Robbins, P.F.1    Morgan, R.A.2    Feldman, S.A.3    Yang, J.C.4    Sherry, R.M.5    Dudley, M.E.6
  • 15
    • 69249221308 scopus 로고    scopus 로고
    • Efficient nonviral sleeping beauty transposon-based tcr gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity
    • Peng PD, Cohen CJ, Yang S, Hsu C, Jones S, Zhao Y et al. Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity. Gene Therapy 2009; 16: 1042-1049.
    • (2009) Gene Therapy , vol.16 , pp. 1042-1049
    • Peng, P.D.1    Cohen, C.J.2    Yang, S.3    Hsu, C.4    Jones, S.5    Zhao, Y.6
  • 16
    • 84879545641 scopus 로고    scopus 로고
    • Comparison of lentiviral and sleeping beauty mediated alphabeta t cell receptor gene transfer
    • Field AC, Vink C, Gabriel R, Al-Subki R, Schmidt M, Goulden N et al. Comparison of lentiviral and sleeping beauty mediated alphabeta T cell receptor gene transfer. PLoS One 2013; 8: e68201.
    • (2013) PLoS One , vol.8 , pp. e68201
    • Field, A.C.1    Vink, C.2    Gabriel, R.3    Al-Subki, R.4    Schmidt, M.5    Goulden, N.6
  • 17
    • 77950953208 scopus 로고    scopus 로고
    • PiggyBac transposon/transposase system to generate cd19-specific t cells for the treatment of b-lineage malignancies
    • Manuri PV, Wilson MH, Maiti SN, Mi T, Singh H, Olivares S et al. piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies. Hum Gene Ther 2010; 21: 427-437.
    • (2010) Hum Gene Ther , vol.21 , pp. 427-437
    • Manuri, P.V.1    Wilson, M.H.2    Maiti, S.N.3    Mi, T.4    Singh, H.5    Olivares, S.6
  • 18
    • 82955187824 scopus 로고    scopus 로고
    • PiggyBacmediated cancer immunotherapy using ebv-specific cytotoxic t-cells expressing her2-specific chimeric antigen receptor
    • Nakazawa Y, Huye LE, Salsman VS, Leen AM, Ahmed N, Rollins L et al. PiggyBacmediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor. Mol Ther 2011; 19: 2133-2143.
    • (2011) Mol Ther , vol.19 , pp. 2133-2143
    • Nakazawa, Y.1    Huye, L.E.2    Salsman, V.S.3    Leen, A.M.4    Ahmed, N.5    Rollins, L.6
  • 19
    • 84905440832 scopus 로고    scopus 로고
    • Antileukemic potency of piggybac-mediated cd19-specific t cells against refractory philadelphia chromosome-positive acute lymphoblastic leukemia
    • Saito S, Nakazawa Y, Sueki A, Matsuda K, Tanaka M, Yanagisawa R et al. Antileukemic potency of piggyBac-mediated CD19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Cytotherapy 2014; 16: 1257-1269.
    • (2014) Cytotherapy , vol.16 , pp. 1257-1269
    • Saito, S.1    Nakazawa, Y.2    Sueki, A.3    Matsuda, K.4    Tanaka, M.5    Yanagisawa, R.6
  • 20
    • 42349088534 scopus 로고    scopus 로고
    • Redirecting specificity of t-cell populations for cd19 using the sleeping beauty system
    • Singh H, Manuri PR, Olivares S, Dara N, Dawson MJ, Huls H et al. Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system. Cancer Res 2008; 68: 2961-2971.
    • (2008) Cancer Res , vol.68 , pp. 2961-2971
    • Singh, H.1    Manuri, P.R.2    Olivares, S.3    Dara, N.4    Dawson, M.J.5    Huls, H.6
  • 21
    • 39849086801 scopus 로고    scopus 로고
    • Sleeping beauty transposon-mediated engineering of human primary t cells for therapy of cd19+ lymphoid malignancies
    • Huang X, Guo H, Kang J, Choi S, Zhou TC, Tammana S et al. Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies. Mol Ther 2008; 16: 580-589.
    • (2008) Mol Ther , vol.16 , pp. 580-589
    • Huang, X.1    Guo, H.2    Kang, J.3    Choi, S.4    Zhou, T.C.5    Tammana, S.6
  • 22
    • 84855410248 scopus 로고    scopus 로고
    • Genetically modified t cells targeting interleukin-11 receptor alpha-chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases
    • Huang G, Yu L, Cooper LJ, Hollomon M, Huls H, Kleinerman ES. Genetically modified T cells targeting interleukin-11 receptor alpha-chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases. Cancer Res 2012; 72: 271-281.
    • (2012) Cancer Res , vol.72 , pp. 271-281
    • Huang, G.1    Yu, L.2    Cooper, L.J.3    Hollomon, M.4    Huls, H.5    Kleinerman, E.S.6
  • 23
  • 24
    • 0030662074 scopus 로고    scopus 로고
    • Molecular reconstruction of sleeping beauty, a tc1-like transposon from fish, and its transposition in human cells
    • Ivics Z, Hackett PB, Plasterk RH, Izsvak Z. Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 1997; 91: 501-510.
    • (1997) Cell , vol.91 , pp. 501-510
    • Ivics, Z.1    Hackett, P.B.2    Plasterk, R.H.3    Izsvak, Z.4
  • 25
    • 0029895619 scopus 로고    scopus 로고
    • Identification of functional domains and evolution of tc1-like transposable elements
    • Ivics Z, Izsvak Z, Minter A, Hackett PB. Identification of functional domains and evolution of Tc1-like transposable elements. Proc Natl Acad Sci USA 1996; 93: 5008-5013.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5008-5013
    • Ivics, Z.1    Izsvak, Z.2    Minter, A.3    Hackett, P.B.4
  • 26
    • 1342311458 scopus 로고    scopus 로고
    • Sleeping beauty transposition: Biology and applications for molecular therapy
    • Izsvak Z, Ivics Z. Sleeping beauty transposition: biology and applications for molecular therapy. Mol Ther 2004; 9: 147-156.
    • (2004) Mol Ther , vol.9 , pp. 147-156
    • Izsvak, Z.1    Ivics, Z.2
  • 27
    • 79955998860 scopus 로고    scopus 로고
    • Efficacy and safety of sleeping beauty transposon-mediated gene transfer in preclinical animal studies
    • Hackett PB Jr., Aronovich EL, Hunter D, Urness M, Bell JB, Kass SJ et al. Efficacy and safety of Sleeping Beauty transposon-mediated gene transfer in preclinical animal studies. Curr Gene Ther 2011; 11: 341-349.
    • (2011) Curr Gene Ther , vol.11 , pp. 341-349
    • Hackett, P.B.1    Aronovich, E.L.2    Hunter, D.3    Urness, M.4    Bell, J.B.5    Kass, S.J.6
  • 28
    • 84875138464 scopus 로고    scopus 로고
    • Evaluating risks of insertional mutagenesis by dna transposons in gene therapy
    • Hackett PB, Largaespada DA, Switzer KC, Cooper LJ. Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy. Transl Res 2013; 161: 265-283.
    • (2013) Transl Res , vol.161 , pp. 265-283
    • Hackett, P.B.1    Largaespada, D.A.2    Switzer, K.C.3    Cooper, L.J.4
  • 29
    • 84890209444 scopus 로고    scopus 로고
    • A new approach to gene therapy using sleeping beauty to genetically modify clinical-grade t cells to target cd19
    • Singh H, Huls H, Kebriaei P, Cooper LJ. A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19. Immunol Rev 2014; 257: 181-190.
    • (2014) Immunol Rev , vol.257 , pp. 181-190
    • Singh, H.1    Huls, H.2    Kebriaei, P.3    Cooper, L.J.4
  • 30
    • 84861674447 scopus 로고    scopus 로고
    • Infusing cd19- directed t cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced b-lymphoid malignancies
    • Kebriaei P, Huls H, Jena B, Munsell M, Jackson R, Lee DA et al. Infusing CD19- directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies. Hum Gene Ther 2012; 23: 444-450.
    • (2012) Hum Gene Ther , vol.23 , pp. 444-450
    • Kebriaei, P.1    Huls, H.2    Jena, B.3    Munsell, M.4    Jackson, R.5    Lee, D.A.6
  • 31
    • 84878547375 scopus 로고    scopus 로고
    • Manufacture of clinical-grade cd19-specific t cells stably expressing chimeric antigen receptor using sleeping beauty system and artificial antigen presenting cells
    • Singh H, Figliola MJ, Dawson MJ, Olivares S, Zhang L, Yang G et al. Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells. PLoS One 2013; 8: e64138.
    • (2013) PLoS One , vol.8 , pp. e64138
    • Singh, H.1    Figliola, M.J.2    Dawson, M.J.3    Olivares, S.4    Zhang, L.5    Yang, G.6
  • 32
    • 84868221578 scopus 로고    scopus 로고
    • Phenotypic and functional attributes of lentivirus-modified cd19-specific human cd8+ central memory t cells manufactured at clinical scale
    • Wang X, Naranjo A, Brown CE, Bautista C, Wong CW, Chang WC et al. Phenotypic and functional attributes of lentivirus-modified CD19-specific human CD8+ central memory T cells manufactured at clinical scale. J Immunother 2012; 35: 689-701.
    • (2012) J Immunother , vol.35 , pp. 689-701
    • Wang, X.1    Naranjo, A.2    Brown, C.E.3    Bautista, C.4    Wong, C.W.5    Chang, W.C.6
  • 33
    • 63649112916 scopus 로고    scopus 로고
    • Manufacturing validation of biologically functional t cells targeted to cd19 antigen for autologous adoptive cell therapy
    • Hollyman D, Stefanski J, Przybylowski M, Bartido S, Borquez-Ojeda O, Taylor C et al. Manufacturing validation of biologically functional T cells targeted to CD19 antigen for autologous adoptive cell therapy. J Immunother 2009; 32: 169-180.
    • (2009) J Immunother , vol.32 , pp. 169-180
    • Hollyman, D.1    Stefanski, J.2    Przybylowski, M.3    Bartido, S.4    Borquez-Ojeda, O.5    Taylor, C.6
  • 35
    • 0025361125 scopus 로고
    • The use of anti-cd3 and anti-cd28 monoclonal antibodies to clone and expand human antigen-specific t cells
    • Riddell SR, Greenberg PD. The use of anti-CD3 and anti-CD28 monoclonal antibodies to clone and expand human antigen-specific T cells. J Immunol Methods 1990; 128: 189-201.
    • (1990) J Immunol Methods , vol.128 , pp. 189-201
    • Riddell, S.R.1    Greenberg, P.D.2
  • 36
    • 0037441593 scopus 로고    scopus 로고
    • T-cell clones can be rendered specific for cd19: Toward the selective augmentation of the graft-versus-b-lineage leukemia effect
    • Cooper LJ, Topp MS, Serrano LM, Gonzalez S, Chang WC, Naranjo A et al. T-cell clones can be rendered specific for CD19: toward the selective augmentation of the graft-versus-B-lineage leukemia effect. Blood 2003; 101: 1637-1644.
    • (2003) Blood , vol.101 , pp. 1637-1644
    • Cooper, L.J.1    Topp, M.S.2    Serrano, L.M.3    Gonzalez, S.4    Chang, W.C.5    Naranjo, A.6
  • 37
    • 13544273197 scopus 로고    scopus 로고
    • Enhanced antilymphoma efficacy of cd19-redirected influenza mp1-specific ctls by cotransfer of t cells modified to present influenza mp1
    • Cooper LJ, Al-Kadhimi Z, Serrano LM, Pfeiffer T, Olivares S, Castro A et al. Enhanced antilymphoma efficacy of CD19-redirected influenza MP1-specific CTLs by cotransfer of T cells modified to present influenza MP1. Blood 2005; 105: 1622-1631.
    • (2005) Blood , vol.105 , pp. 1622-1631
    • Cooper, L.J.1    Al-Kadhimi, Z.2    Serrano, L.M.3    Pfeiffer, T.4    Olivares, S.5    Castro, A.6
  • 38
    • 34250365425 scopus 로고    scopus 로고
    • Antigen-independent and antigen-dependent methods to numerically expand cd19-specific cd8(+) t cells
    • Numbenjapon T, Serrano LM, Chang WC, Forman SJ, Jensen MC, Cooper LJ. Antigen-independent and antigen-dependent methods to numerically expand CD19-specific CD8(+) T cells. Exp Hematol 2007; 35: 1083-1090.
    • (2007) Exp Hematol , vol.35 , pp. 1083-1090
    • Numbenjapon, T.1    Serrano, L.M.2    Chang, W.C.3    Forman, S.J.4    Jensen, M.C.5    Cooper, L.J.6
  • 39
    • 33750043473 scopus 로고    scopus 로고
    • Characterization of an artificial antigen-presenting cell to propagate cytolytic cd19-specific t cells
    • Numbenjapon T, Serrano LM, Singh H, Kowolik CM, Olivares S, Gonzalez N et al. Characterization of an artificial antigen-presenting cell to propagate cytolytic CD19-specific T cells. Leukemia 2006; 20: 1889-1892.
    • (2006) Leukemia , vol.20 , pp. 1889-1892
    • Numbenjapon, T.1    Serrano, L.M.2    Singh, H.3    Kowolik, C.M.4    Olivares, S.5    Gonzalez, N.6
  • 40
    • 0027471898 scopus 로고
    • Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibodybinding domains and the gamma or zeta subunits of the immunoglobulin and t-cell receptors
    • Eshhar Z, Waks T, Gross G, Schindler DG. Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibodybinding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors. Proc Natl Acad Sci USA 1993; 90: 720-724.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 720-724
    • Eshhar, Z.1    Waks, T.2    Gross, G.3    Schindler, D.G.4
  • 41
    • 65249101637 scopus 로고    scopus 로고
    • The promise and potential pitfalls of chimeric antigen receptors
    • Sadelain M, Brentjens R, Riviere I. The promise and potential pitfalls of chimeric antigen receptors. Curr Opin Immunol 2009; 21: 215-223.
    • (2009) Curr Opin Immunol , vol.21 , pp. 215-223
    • Sadelain, M.1    Brentjens, R.2    Riviere, I.3
  • 42
    • 76749120309 scopus 로고    scopus 로고
    • A herceptinbased chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced t lymphocytes and antitumor activity
    • Zhao Y, Wang QJ, Yang S, Kochenderfer JN, Zheng Z, Zhong X et al. A herceptinbased chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity. J Immunol 2009; 183: 5563-5574.
    • (2009) J Immunol , vol.183 , pp. 5563-5574
    • Zhao, Y.1    Wang, Q.J.2    Yang, S.3    Kochenderfer, J.N.4    Zheng, Z.5    Zhong, X.6
  • 43
    • 34548485103 scopus 로고    scopus 로고
    • Optimizing adoptive polyclonal t cell immunotherapy of lymphomas, using a chimeric t cell receptor possessing cd28 and cd137 costimulatory domains
    • Wang J, Jensen M, Lin Y, Sui X, Chen E, Lindgren CG et al. Optimizing adoptive polyclonal T cell immunotherapy of lymphomas, using a chimeric T cell receptor possessing CD28 and CD137 costimulatory domains. Hum Gene Ther 2007; 18: 712-725.
    • (2007) Hum Gene Ther , vol.18 , pp. 712-725
    • Wang, J.1    Jensen, M.2    Lin, Y.3    Sui, X.4    Chen, E.5    Lindgren, C.G.6
  • 44
    • 70349439277 scopus 로고    scopus 로고
    • Immunotherapy of metastatic melanoma using genetically engineered gd2-specific t cells
    • Yvon E, Del Vecchio M, Savoldo B, Hoyos V, Dutour A, Anichini A et al. Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells. Clin Cancer Res 2009; 15: 5852-5860.
    • (2009) Clin Cancer Res , vol.15 , pp. 5852-5860
    • Yvon, E.1    Del Vecchio, M.2    Savoldo, B.3    Hoyos, V.4    Dutour, A.5    Anichini, A.6
  • 45
    • 33845294816 scopus 로고    scopus 로고
    • CD28 costimulation provided through a cd19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred t cells
    • Kowolik CM, Topp MS, Gonzalez S, Pfeiffer T, Olivares S, Gonzalez N et al. CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells. Cancer Res 2006; 66: 10995-11004.
    • (2006) Cancer Res , vol.66 , pp. 10995-11004
    • Kowolik, C.M.1    Topp, M.S.2    Gonzalez, S.3    Pfeiffer, T.4    Olivares, S.5    Gonzalez, N.6
  • 46
    • 3042551216 scopus 로고    scopus 로고
    • Chimeric receptors with 4-1bb signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia
    • Imai C, Mihara K, Andreansky M, Nicholson IC, Pui CH, Geiger TL et al. Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. Leukemia 2004; 18: 676-684.
    • (2004) Leukemia , vol.18 , pp. 676-684
    • Imai, C.1    Mihara, K.2    Andreansky, M.3    Nicholson, I.C.4    Pui, C.H.5    Geiger, T.L.6
  • 47
    • 30044442768 scopus 로고    scopus 로고
    • Adoptive transfer of t cells modified with a humanized chimeric receptor gene inhibits growth of lewis-y-expressing tumors in mice
    • Westwood JA, Smyth MJ, Teng MW, Moeller M, Trapani JA, Scott AM et al. Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice. Proc Natl Acad Sci USA 2005; 102: 19051-19056.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 19051-19056
    • Westwood, J.A.1    Smyth, M.J.2    Teng, M.W.3    Moeller, M.4    Trapani, J.A.5    Scott, A.M.6
  • 48
    • 84877626190 scopus 로고    scopus 로고
    • Clinical application of sleeping beauty and artificial antigen presenting cells to genetically modify t cells from peripheral and umbilical cord blood
    • Huls MH, Figliola MJ, Dawson MJ, Olivares S, Kebriaei P, Shpall EJ et al. Clinical application of sleeping beauty and artificial antigen presenting cells to genetically modify T cells from peripheral and umbilical cord blood. J Vis Exp 2013; 1: e50070.
    • (2013) J Vis Exp , vol.1 , pp. e50070
    • Huls, M.H.1    Figliola, M.J.2    Dawson, M.J.3    Olivares, S.4    Kebriaei, P.5    Shpall, E.J.6
  • 49
    • 79956149133 scopus 로고    scopus 로고
    • Reprogramming cd19-specific t cells with il-21 signaling can improve adoptive immunotherapy of b-lineage malignancies
    • Singh H, Figliola MJ, Dawson MJ, Huls H, Olivares S, Switzer K et al. Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies. Cancer Res 2011; 71: 3516-3527.
    • (2011) Cancer Res , vol.71 , pp. 3516-3527
    • Singh, H.1    Figliola, M.J.2    Dawson, M.J.3    Huls, H.4    Olivares, S.5    Switzer, K.6
  • 50
    • 84898009421 scopus 로고    scopus 로고
    • Universal artificial antigen presenting cells to selectively propagate t cells expressing chimeric antigen receptor independent of specificity
    • Rushworth D, Jena B, Olivares S, Maiti S, Briggs N, Somanchi S et al. Universal artificial antigen presenting cells to selectively propagate T cells expressing chimeric antigen receptor independent of specificity. J Immunother 2014; 37: 204-213.
    • (2014) J Immunother , vol.37 , pp. 204-213
    • Rushworth, D.1    Jena, B.2    Olivares, S.3    Maiti, S.4    Briggs, N.5    Somanchi, S.6
  • 51
    • 77149175420 scopus 로고    scopus 로고
    • Disposable bioreactors: The current stateof- the-art and recommended applications in biotechnology
    • Eibl R, Kaiser S, Lombriser R, Eibl D. Disposable bioreactors: the current stateof- the-art and recommended applications in biotechnology. Appl Microbiol Biotechnol 2010; 86: 41-49.
    • (2010) Appl Microbiol Biotechnol , vol.86 , pp. 41-49
    • Eibl, R.1    Kaiser, S.2    Lombriser, R.3    Eibl, D.4
  • 52
    • 34547775694 scopus 로고    scopus 로고
    • Manufacturing of large numbers of patient-specific t cells for adoptive immunotherapy: An approach to improving product safety, composition, and production capacity
    • Tran CA, Burton L, Russom D, Wagner JR, Jensen MC, Forman SJ et al. Manufacturing of large numbers of patient-specific T cells for adoptive immunotherapy: an approach to improving product safety, composition, and production capacity. J Immunother 2007; 30: 644-654.
    • (2007) J Immunother , vol.30 , pp. 644-654
    • Tran, C.A.1    Burton, L.2    Russom, D.3    Wagner, J.R.4    Jensen, M.C.5    Forman, S.J.6
  • 53
    • 84859179612 scopus 로고    scopus 로고
    • Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the wave(r) bioreactor
    • Somerville RP, Devillier L, Parkhurst MR, Rosenberg SA, Dudley ME. Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE(R) bioreactor. J Transl Med 2012; 10: 69.
    • (2012) J Transl Med , vol.10 , pp. 69
    • Somerville, R.P.1    Devillier, L.2    Parkhurst, M.R.3    Rosenberg, S.A.4    Dudley, M.E.5
  • 54
    • 84873675111 scopus 로고    scopus 로고
    • Integrated clinical scale manufacturing system for cellular products derived by magnetic cell separation, centrifugation and cell culture
    • Apel M, Brüning M, Granzin M, Essl M, Stuth J, Blaschke J et al. Integrated clinical scale manufacturing system for cellular products derived by magnetic cell separation, centrifugation and cell culture. Chemie Ingenieur Technik 2013; 85: 103-110.
    • (2013) Chemie Ingenieur Technik , vol.85 , pp. 103-110
    • Apel, M.1    Brüning, M.2    Granzin, M.3    Essl, M.4    Stuth, J.5    Blaschke, J.6
  • 55
    • 84924757997 scopus 로고    scopus 로고
    • Automated production of clinical-grade cmv-specific t cells to implement immunotherapy at the bedside
    • Tewari P, Kumaresan PR, Figliola M, Huls H, Longin K, Ruhnke K et al. Automated production of clinical-grade CMV-specific T cells to implement immunotherapy at the bedside. Biol Blood Marrow Transplant 2014; 20: S136-S137.
    • (2014) Biol Blood Marrow Transplant , vol.20 , pp. S136-S137
    • Tewari, P.1    Kumaresan, P.R.2    Figliola, M.3    Huls, H.4    Longin, K.5    Ruhnke, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.