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Volumn 77, Issue , 2016, Pages 307-360

Estrogens and Coronary Artery Disease: New Clinical Perspectives

Author keywords

Artery; Atherosclerosis; Blood pressure; Cholesterol; Clinical medicine; Coronary artery disease; Drug therapy; Dyslipidemia; Endothelium; Estrogen; Faslodex ; Fulvestrant; GPER; GPER 1; GPR30; Heart; Hormone replacement therapy; Hormone therapy; Hormones; Hypertension; ICI 182,780; Inflammation; Menopause; Myocardium; Niacin; Nitric oxide; Obesity; Patients; Personalized medicine; Risk factors; Tamoxifen; Theranostics; Vascular

Indexed keywords

CYCLIC AMP; ESTROGEN; ESTROGEN RECEPTOR; G PROTEIN COUPLED ESTROGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; NITRIC OXIDE; PROSTANOID; UNCLASSIFIED DRUG; LIGAND; SELECTIVE ESTROGEN RECEPTOR MODULATOR;

EID: 84979671221     PISSN: 10543589     EISSN: 15578925     Source Type: Book Series    
DOI: 10.1016/bs.apha.2016.05.003     Document Type: Chapter
Times cited : (65)

References (314)
  • 1
    • 80051796178 scopus 로고    scopus 로고
    • Benzothiophene selective estrogen receptor modulators provide neuroprotection by a novel GPR30-dependent mechanism
    • Abdelhamid, R., Luo, J., Vandevrede, L., Kundu, I., Michalsen, B., Litosh, V.A., Thatcher, G.R., Benzothiophene selective estrogen receptor modulators provide neuroprotection by a novel GPR30-dependent mechanism. ACS Chemical Neuroscience 2 (2011), 256–268, 10.1021/cn100106a.
    • (2011) ACS Chemical Neuroscience , vol.2 , pp. 256-268
    • Abdelhamid, R.1    Luo, J.2    Vandevrede, L.3    Kundu, I.4    Michalsen, B.5    Litosh, V.A.6    Thatcher, G.R.7
  • 2
    • 40949095655 scopus 로고    scopus 로고
    • Guide to receptors and channels (GRAC)
    • 0707746 [pii] (3rd edition)
    • Alexander, S.P., Mathie, A., Peters, J.A., Guide to receptors and channels (GRAC). British Journal of Pharmacology 153:Suppl. 2 (2008), S1–S209, 10.1038/sj.bjp.0707746 0707746 [pii] (3rd edition).
    • (2008) British Journal of Pharmacology , vol.153 , pp. S1-S209
    • Alexander, S.P.1    Mathie, A.2    Peters, J.A.3
  • 3
    • 84928008470 scopus 로고    scopus 로고
    • G protein-coupled estrogen receptor-mediated effects on cytosolic calcium and nanomechanics in brain microvascular endothelial cells
    • Altmann, J.B., Yan, G., Meeks, J.F., Abood, M.E., Brailoiu, E., Brailoiu, G.C., G protein-coupled estrogen receptor-mediated effects on cytosolic calcium and nanomechanics in brain microvascular endothelial cells. Journal of Neurochemistry 133 (2015), 629–639, 10.1111/jnc.13066.
    • (2015) Journal of Neurochemistry , vol.133 , pp. 629-639
    • Altmann, J.B.1    Yan, G.2    Meeks, J.F.3    Abood, M.E.4    Brailoiu, E.5    Brailoiu, G.C.6
  • 4
    • 84901280200 scopus 로고    scopus 로고
    • Vasodilatory effects of the selective GPER agonist G-1 is maximal in arteries of postmenopausal women
    • Arefin, S., Simoncini, T., Wieland, R., Hammarqvist, F., Spina, S., Goglia, L., Kublickiene, K., Vasodilatory effects of the selective GPER agonist G-1 is maximal in arteries of postmenopausal women. Maturitas 78 (2014), 123–130, 10.1016/j.maturitas.2014.04.002.
    • (2014) Maturitas , vol.78 , pp. 123-130
    • Arefin, S.1    Simoncini, T.2    Wieland, R.3    Hammarqvist, F.4    Spina, S.5    Goglia, L.6    Kublickiene, K.7
  • 8
    • 84908042332 scopus 로고    scopus 로고
    • Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function
    • Barrett Mueller, K., Lu, Q., Mohammad, N.N., Luu, V., McCurley, A., Williams, G.H., Jaffe, I.Z., Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function. Endocrinology 155 (2014), 4461–4472, 10.1210/en.2014-1270.
    • (2014) Endocrinology , vol.155 , pp. 4461-4472
    • Barrett Mueller, K.1    Lu, Q.2    Mohammad, N.N.3    Luu, V.4    McCurley, A.5    Williams, G.H.6    Jaffe, I.Z.7
  • 9
    • 84879422023 scopus 로고    scopus 로고
    • Menopause, atherosclerosis, and coronary artery disease
    • Barrett-Connor, E., Menopause, atherosclerosis, and coronary artery disease. Current Opinion in Pharmacology 13 (2013), 186–191, 10.1016/j.coph.2013.01.005.
    • (2013) Current Opinion in Pharmacology , vol.13 , pp. 186-191
    • Barrett-Connor, E.1
  • 11
    • 0035023005 scopus 로고    scopus 로고
    • Postmenopausal oestrogen replacement therapy and atherosclerosis: Can current compounds provide cardiovascular protection?
    • Barton, M., Postmenopausal oestrogen replacement therapy and atherosclerosis: Can current compounds provide cardiovascular protection?. Expert Opinion on Investigational Drugs 10 (2001), 789–809, 10.1517/13543784.10.5.789.
    • (2001) Expert Opinion on Investigational Drugs , vol.10 , pp. 789-809
    • Barton, M.1
  • 12
    • 50249165289 scopus 로고    scopus 로고
    • Reversal of proteinuric renal disease and the emerging role of endothelin
    • Barton, M., Reversal of proteinuric renal disease and the emerging role of endothelin. Nature Clinical Practice Nephrology 4 (2008), 490–501, 10.1038/ncpneph0891.
    • (2008) Nature Clinical Practice Nephrology , vol.4 , pp. 490-501
    • Barton, M.1
  • 13
    • 77957905257 scopus 로고    scopus 로고
    • Obesity and aging: Determinants of endothelial cell dysfunction and atherosclerosis
    • Barton, M., Obesity and aging: Determinants of endothelial cell dysfunction and atherosclerosis. Pflügers Archiv 460 (2010), 825–837, 10.1007/s00424-010-0860-y.
    • (2010) Pflügers Archiv , vol.460 , pp. 825-837
    • Barton, M.1
  • 14
    • 79958031263 scopus 로고    scopus 로고
    • The discovery of endothelium-dependent contraction: The legacy of Paul M. Vanhoutte
    • Barton, M., The discovery of endothelium-dependent contraction: The legacy of Paul M. Vanhoutte. Pharmacological Research 63 (2011), 455–462, 10.1016/j.phrs.2011.02.013.
    • (2011) Pharmacological Research , vol.63 , pp. 455-462
    • Barton, M.1
  • 15
    • 84856848766 scopus 로고    scopus 로고
    • Childhood obesity: A life-long health risk
    • Barton, M., Childhood obesity: A life-long health risk. Acta Pharmacologica Sinica 33 (2012), 189–193, 10.1038/aps.2011.204.
    • (2012) Acta Pharmacologica Sinica , vol.33 , pp. 189-193
    • Barton, M.1
  • 16
    • 84863983261 scopus 로고    scopus 로고
    • Position paper: The membrane estrogen receptor GPER—Clues and questions
    • Barton, M., Position paper: The membrane estrogen receptor GPER—Clues and questions. Steroids 77 (2012), 935–942, 10.1016/j.steroids.2012.04.001.
    • (2012) Steroids , vol.77 , pp. 935-942
    • Barton, M.1
  • 17
    • 84880134748 scopus 로고    scopus 로고
    • Cholesterol and atherosclerosis: Modulation by oestrogen
    • Barton, M., Cholesterol and atherosclerosis: Modulation by oestrogen. Current Opinion in Lipidology 24 (2013), 214–220, 10.1097/MOL.0b013e3283613a94.
    • (2013) Current Opinion in Lipidology , vol.24 , pp. 214-220
    • Barton, M.1
  • 18
    • 84879422450 scopus 로고    scopus 로고
    • Mechanisms and therapy of atherosclerosis and its clinical complications
    • Barton, M., Mechanisms and therapy of atherosclerosis and its clinical complications. Current Opinion in Pharmacology 13 (2013), 149–153, 10.1016/j.coph.2013.05.001.
    • (2013) Current Opinion in Pharmacology , vol.13 , pp. 149-153
    • Barton, M.1
  • 19
    • 84879417793 scopus 로고    scopus 로고
    • Prevention and endothelial therapy of coronary artery disease
    • Barton, M., Prevention and endothelial therapy of coronary artery disease. Current Opinion in Pharmacology 13 (2013), 226–241, 10.1016/j.coph.2013.05.005.
    • (2013) Current Opinion in Pharmacology , vol.13 , pp. 226-241
    • Barton, M.1
  • 20
    • 84920757746 scopus 로고    scopus 로고
    • Aging and endothelin: Determinants of disease
    • Barton, M., Aging and endothelin: Determinants of disease. Life Sciences 118 (2014), 97–109, 10.1016/j.lfs.2014.09.009.
    • (2014) Life Sciences , vol.118 , pp. 97-109
    • Barton, M.1
  • 21
    • 84960969522 scopus 로고    scopus 로고
    • Not lost in translation: Emerging clinical importance of the G protein-coupled estrogen receptor GPER
    • e-pub January 24
    • Barton, M., Not lost in translation: Emerging clinical importance of the G protein-coupled estrogen receptor GPER. Steroids, 2016 e-pub January 24.
    • (2016) Steroids
    • Barton, M.1
  • 22
    • 84855677053 scopus 로고    scopus 로고
    • Obesity and risk of vascular disease: Importance of endothelium-dependent vasoconstriction
    • Barton, M., Baretella, O., Meyer, M.R., Obesity and risk of vascular disease: Importance of endothelium-dependent vasoconstriction. British Journal of Pharmacology 165 (2012), 591–602, 10.1111/j.1476-5381.2011.01472.x.
    • (2012) British Journal of Pharmacology , vol.165 , pp. 591-602
    • Barton, M.1    Baretella, O.2    Meyer, M.R.3
  • 23
    • 84855677053 scopus 로고    scopus 로고
    • Obesity and risk of vascular disease: Importance of endothelium-derived vasoconstriction
    • Barton, M., Baretella, O., Meyer, M.R., Obesity and risk of vascular disease: Importance of endothelium-derived vasoconstriction. British Journal of Pharmacology 165 (2012), 591–602, 10.1111/j.1476-5381.2011.01472.x.
    • (2012) British Journal of Pharmacology , vol.165 , pp. 591-602
    • Barton, M.1    Baretella, O.2    Meyer, M.R.3
  • 24
    • 0032217265 scopus 로고    scopus 로고
    • 17β-estradiol acutely improves endothelium-dependent relaxation to bradykinin in isolated human coronary arteries
    • Barton, M., Cremer, J., Mügge, A., 17β-estradiol acutely improves endothelium-dependent relaxation to bradykinin in isolated human coronary arteries. European Journal of Pharmacology 362 (1998), 73–76.
    • (1998) European Journal of Pharmacology , vol.362 , pp. 73-76
    • Barton, M.1    Cremer, J.2    Mügge, A.3
  • 27
    • 84964388680 scopus 로고    scopus 로고
    • Accelerated vascular aging as a paradigm for hypertensive vascular disease: Prevention and therapy
    • 680.e4–686.e4
    • Barton, M., Husmann, M., Meyer, M.R., Accelerated vascular aging as a paradigm for hypertensive vascular disease: Prevention and therapy. The Canadian Journal of Cardiology, 32(5), 2016, 10.1016/j.cjca.2016.02.062 680.e4–686.e4.
    • (2016) The Canadian Journal of Cardiology , vol.32 , Issue.5
    • Barton, M.1    Husmann, M.2    Meyer, M.R.3
  • 28
    • 67649855149 scopus 로고    scopus 로고
    • Postmenopausal hypertension: Mechanisms and therapy
    • Barton, M., Meyer, M.R., Postmenopausal hypertension: Mechanisms and therapy. Hypertension 54 (2009), 11–18.
    • (2009) Hypertension , vol.54 , pp. 11-18
    • Barton, M.1    Meyer, M.R.2
  • 29
    • 84938292786 scopus 로고    scopus 로고
    • Nicolaus Copernicus and the rapid vascular responses to aldosterone
    • Barton, M., Meyer, M.R., Nicolaus Copernicus and the rapid vascular responses to aldosterone. Trends in Endocrinology and Metabolism 26 (2015), 396–398, 10.1016/j.tem.2015.05.005.
    • (2015) Trends in Endocrinology and Metabolism , vol.26 , pp. 396-398
    • Barton, M.1    Meyer, M.R.2
  • 30
    • 84857289097 scopus 로고    scopus 로고
    • WISDOM trial, postmenopausal hormone replacement and cardiovascular events: Why it is still not wise to use equine estrogens
    • Barton, M., Meyer, M.R., Bhattacharya, I., Haas, E., WISDOM trial, postmenopausal hormone replacement and cardiovascular events: Why it is still not wise to use equine estrogens. BMJ, 335, 2007, 239 http://www.bmj.com/rapid-response/2011/2011/2001/wisdom-trial-postmenopausal-hormone-replacement-and-cardiovascular-events-.
    • (2007) BMJ , vol.335 , pp. 239
    • Barton, M.1    Meyer, M.R.2    Bhattacharya, I.3    Haas, E.4
  • 31
    • 34547628345 scopus 로고    scopus 로고
    • Hormone replacement therapy and atherosclerosis in postmenopausal women: Does aging limit therapeutic benefits?
    • Barton, M., Meyer, M.R., Haas, E., Hormone replacement therapy and atherosclerosis in postmenopausal women: Does aging limit therapeutic benefits?. Arteriosclerosis, Thrombosis, and Vascular Biology 27 (2007), 1669–1672.
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , pp. 1669-1672
    • Barton, M.1    Meyer, M.R.2    Haas, E.3
  • 32
    • 84880572564 scopus 로고    scopus 로고
    • Alike but not the same: Anatomic heterogeneity of estrogen receptor-mediated vasodilation
    • Barton, M., Meyer, M.R., Prossnitz, E.R., Alike but not the same: Anatomic heterogeneity of estrogen receptor-mediated vasodilation. Journal of Cardiovascular Pharmacology 62 (2013), 22–25, 10.1097/FJC.0b013e31829709d4.
    • (2013) Journal of Cardiovascular Pharmacology , vol.62 , pp. 22-25
    • Barton, M.1    Meyer, M.R.2    Prossnitz, E.R.3
  • 33
    • 84933676390 scopus 로고    scopus 로고
    • Emerging roles of GPER in diabetes and atherosclerosis
    • Barton, M., Prossnitz, E.R., Emerging roles of GPER in diabetes and atherosclerosis. Trends in Endocrinology and Metabolism 26 (2015), 185–192, 10.1016/j.tem.2015.02.003.
    • (2015) Trends in Endocrinology and Metabolism , vol.26 , pp. 185-192
    • Barton, M.1    Prossnitz, E.R.2
  • 34
    • 0019863079 scopus 로고
    • Effects of 17 beta-estradiol on the biosynthesis of collagen in cultured bovine aortic smooth muscle cells
    • Beldekas, J.C., Smith, B., Gerstenfeld, L.C., Sonenshein, G.E., Franzblau, C., Effects of 17 beta-estradiol on the biosynthesis of collagen in cultured bovine aortic smooth muscle cells. Biochemistry 20 (1981), 2162–2167.
    • (1981) Biochemistry , vol.20 , pp. 2162-2167
    • Beldekas, J.C.1    Smith, B.2    Gerstenfeld, L.C.3    Sonenshein, G.E.4    Franzblau, C.5
  • 35
    • 41449111027 scopus 로고    scopus 로고
    • Selective activation of G-protein coupled estrogen receptor GPR30 inhibits vasoconstriction and induces vascular smooth muscle cell ERK1/2 phosphorylation
    • Bhattacharya, I., Damjanovic, M., Hirsiger, S., Haas, E., Gut, A., Mueller-Guerre, L., Barton, M., Selective activation of G-protein coupled estrogen receptor GPR30 inhibits vasoconstriction and induces vascular smooth muscle cell ERK1/2 phosphorylation. Circulation, 116, 2007, II74.
    • (2007) Circulation , vol.116 , pp. II74
    • Bhattacharya, I.1    Damjanovic, M.2    Hirsiger, S.3    Haas, E.4    Gut, A.5    Mueller-Guerre, L.6    Barton, M.7
  • 37
    • 0031008135 scopus 로고    scopus 로고
    • Molecular cloning and tissue expression of a novel orphan G protein-coupled receptor from rat lung
    • Bonini, J.A., Anderson, S.M., Steiner, D.F., Molecular cloning and tissue expression of a novel orphan G protein-coupled receptor from rat lung. Biochemical and Biophysical Research Communications 234 (1997), 190–193, 10.1006/bbrc.1997.6591.
    • (1997) Biochemical and Biophysical Research Communications , vol.234 , pp. 190-193
    • Bonini, J.A.1    Anderson, S.M.2    Steiner, D.F.3
  • 40
    • 0343632368 scopus 로고    scopus 로고
    • Gender differences in the generation of superoxide anions in the rat aorta
    • Brandes, R.P., Mügge, A., Gender differences in the generation of superoxide anions in the rat aorta. Life Sciences 60 (1997), 391–396.
    • (1997) Life Sciences , vol.60 , pp. 391-396
    • Brandes, R.P.1    Mügge, A.2
  • 41
    • 84878014504 scopus 로고    scopus 로고
    • Stroke increases g protein-coupled estrogen receptor expression in the brain of male but not female mice
    • Broughton, B.R., Brait, V.H., Guida, E., Lee, S., Arumugam, T.V., Gardiner-Mann, C.V., Sobey, C.G., Stroke increases g protein-coupled estrogen receptor expression in the brain of male but not female mice. Neurosignals 21 (2013), 229–239, 10.1159/000338019.
    • (2013) Neurosignals , vol.21 , pp. 229-239
    • Broughton, B.R.1    Brait, V.H.2    Guida, E.3    Lee, S.4    Arumugam, T.V.5    Gardiner-Mann, C.V.6    Sobey, C.G.7
  • 42
    • 84899141517 scopus 로고    scopus 로고
    • Sex-dependent effects of G protein-coupled estrogen receptor activity on outcome after ischemic stroke
    • Broughton, B.R., Brait, V.H., Kim, H.A., Lee, S., Chu, H.X., Gardiner-Mann, C.V., Sobey, C.G., Sex-dependent effects of G protein-coupled estrogen receptor activity on outcome after ischemic stroke. Stroke 45 (2014), 835–841, 10.1161/STROKEAHA.113.001499.
    • (2014) Stroke , vol.45 , pp. 835-841
    • Broughton, B.R.1    Brait, V.H.2    Kim, H.A.3    Lee, S.4    Chu, H.X.5    Gardiner-Mann, C.V.6    Sobey, C.G.7
  • 44
    • 0035150589 scopus 로고    scopus 로고
    • Effect of menopause on plaque morphologic characteristics in coronary atherosclerosis
    • Burke, A.P., Farb, A., Malcom, G., Virmani, R., Effect of menopause on plaque morphologic characteristics in coronary atherosclerosis. American Heart Journal 141 (2001), S58–S62.
    • (2001) American Heart Journal , vol.141 , pp. S58-S62
    • Burke, A.P.1    Farb, A.2    Malcom, G.3    Virmani, R.4
  • 45
    • 84866536282 scopus 로고    scopus 로고
    • Estrogen receptors and human disease: An update
    • Burns, K.A., Korach, K.S., Estrogen receptors and human disease: An update. Archives of Toxicology 86 (2012), 1491–1504, 10.1007/s00204-012-0868-5.
    • (2012) Archives of Toxicology , vol.86 , pp. 1491-1504
    • Burns, K.A.1    Korach, K.S.2
  • 46
    • 0028942436 scopus 로고
    • Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988–1991
    • Burt, V.L., Whelton, P., Roccella, E.J., Brown, C., Cutler, J.A., Higgins, M., Labarthe, D., Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988–1991. Hypertension 25 (1995), 305–313.
    • (1995) Hypertension , vol.25 , pp. 305-313
    • Burt, V.L.1    Whelton, P.2    Roccella, E.J.3    Brown, C.4    Cutler, J.A.5    Higgins, M.6    Labarthe, D.7
  • 47
    • 0004715955 scopus 로고
    • Über “Progynon” ein krystallisiertes weibliches Sexualhormon
    • Butenandt, A., Über “Progynon” ein krystallisiertes weibliches Sexualhormon. Die Naturwissenschaften, 17, 1929, 879.
    • (1929) Die Naturwissenschaften , vol.17 , pp. 879
    • Butenandt, A.1
  • 48
    • 0013455221 scopus 로고
    • Über die chemische Untersuchung der Sexualhormone
    • Butenandt, A., Über die chemische Untersuchung der Sexualhormone. Zeitschrift für Angewandte Chemie 44 (1931), 905–916.
    • (1931) Zeitschrift für Angewandte Chemie , vol.44 , pp. 905-916
    • Butenandt, A.1
  • 49
    • 0031282001 scopus 로고    scopus 로고
    • Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer
    • Carmeci, C., Thompson, D.A., Ring, H.Z., Francke, U., Weigel, R.J., Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer. Genomics 45 (1997), 607–617.
    • (1997) Genomics , vol.45 , pp. 607-617
    • Carmeci, C.1    Thompson, D.A.2    Ring, H.Z.3    Francke, U.4    Weigel, R.J.5
  • 51
    • 0343247792 scopus 로고    scopus 로고
    • 17 beta-estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2 + mobilization
    • Caulin-Glaser, T., Garcia-Cardena, G., Sarrel, P., Sessa, W.C., Bender, J.R., 17 beta-estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2 + mobilization. Circulation Research 81 (1997), 885–892.
    • (1997) Circulation Research , vol.81 , pp. 885-892
    • Caulin-Glaser, T.1    Garcia-Cardena, G.2    Sarrel, P.3    Sessa, W.C.4    Bender, J.R.5
  • 53
    • 0034711335 scopus 로고    scopus 로고
    • Estrogen receptor alpha and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae
    • Chambliss, K.L., Yuhanna, I.S., Mineo, C., Liu, P., German, Z., Sherman, T.S., Shaul, P.W., Estrogen receptor alpha and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae. Circulation Research 87 (2000), E44–E52.
    • (2000) Circulation Research , vol.87 , pp. E44-E52
    • Chambliss, K.L.1    Yuhanna, I.S.2    Mineo, C.3    Liu, P.4    German, Z.5    Sherman, T.S.6    Shaul, P.W.7
  • 54
    • 0019158169 scopus 로고
    • Stimulation of prostaglandin cyclooxygenase and prostacyclin synthetase activities by estradiol in rat aortic smooth muscle cells
    • Chang, W.C., Nakao, J., Orimo, H., Murota, S.I., Stimulation of prostaglandin cyclooxygenase and prostacyclin synthetase activities by estradiol in rat aortic smooth muscle cells. Biochimica et Biophysica Acta 620 (1980), 472–482.
    • (1980) Biochimica et Biophysica Acta , vol.620 , pp. 472-482
    • Chang, W.C.1    Nakao, J.2    Orimo, H.3    Murota, S.I.4
  • 55
    • 84890247057 scopus 로고    scopus 로고
    • Anatomical location and redistribution of G protein-coupled estrogen receptor-1 during the estrus cycle in mouse kidney and specific binding to estrogens but not aldosterone
    • Cheng, S.B., Dong, J., Pang, Y., LaRocca, J., Hixon, M., Thomas, P., Filardo, E.J., Anatomical location and redistribution of G protein-coupled estrogen receptor-1 during the estrus cycle in mouse kidney and specific binding to estrogens but not aldosterone. Molecular and Cellular Endocrinology 382 (2014), 950–959, 10.1016/j.mce.2013.11.005.
    • (2014) Molecular and Cellular Endocrinology , vol.382 , pp. 950-959
    • Cheng, S.B.1    Dong, J.2    Pang, Y.3    LaRocca, J.4    Hixon, M.5    Thomas, P.6    Filardo, E.J.7
  • 56
    • 84947800414 scopus 로고    scopus 로고
    • Detection of the phosphorylation of the estrogen receptor alpha as an outcome of GPR30 activation
    • Clark, S., Pollard, K., Rainville, J., Vasudevan, N., Detection of the phosphorylation of the estrogen receptor alpha as an outcome of GPR30 activation. Methods in Molecular Biology 1366 (2016), 457–470, 10.1007/978-1-4939-3127-9_36.
    • (2016) Methods in Molecular Biology , vol.1366 , pp. 457-470
    • Clark, S.1    Pollard, K.2    Rainville, J.3    Vasudevan, N.4
  • 57
    • 34447282249 scopus 로고    scopus 로고
    • Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression
    • Clarkson, T.B., Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression. Menopause 14 (2007), 373–384.
    • (2007) Menopause , vol.14 , pp. 373-384
    • Clarkson, T.B.1
  • 58
    • 61849168916 scopus 로고    scopus 로고
    • Effects of the selective estrogen receptor modulator raloxifene on coronary outcomes in the raloxifene use for the heart trial. Results of subgroup analyses by age and other factors
    • Collins, P., Mosca, L., Geiger, M.J., Grady, D., Kornitzer, M., Amewou-Atisso, M.G., Wenger, N.K., Effects of the selective estrogen receptor modulator raloxifene on coronary outcomes in the raloxifene use for the heart trial. Results of subgroup analyses by age and other factors. Circulation 119 (2009), 922–930.
    • (2009) Circulation , vol.119 , pp. 922-930
    • Collins, P.1    Mosca, L.2    Geiger, M.J.3    Grady, D.4    Kornitzer, M.5    Amewou-Atisso, M.G.6    Wenger, N.K.7
  • 59
    • 0029018514 scopus 로고
    • 17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease
    • Collins, P., Rosano, G.M., Sarrel, P.M., Ulrich, L., Adamopoulos, S., Beale, C.M., Poole-Wilson, P.A., 17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease. Circulation 92 (1995), 24–30.
    • (1995) Circulation , vol.92 , pp. 24-30
    • Collins, P.1    Rosano, G.M.2    Sarrel, P.M.3    Ulrich, L.4    Adamopoulos, S.5    Beale, C.M.6    Poole-Wilson, P.A.7
  • 60
    • 84878145830 scopus 로고    scopus 로고
    • Endogenous sex steroid levels and cardiovascular disease in relation to the menopause: A systematic review
    • Crandall, C.J., Barrett-Connor, E., Endogenous sex steroid levels and cardiovascular disease in relation to the menopause: A systematic review. Endocrinology and Metabolism Clinics of North America 42 (2013), 227–253, 10.1016/j.ecl.2013.02.003.
    • (2013) Endocrinology and Metabolism Clinics of North America , vol.42 , pp. 227-253
    • Crandall, C.J.1    Barrett-Connor, E.2
  • 61
    • 38049059235 scopus 로고    scopus 로고
    • Acute dilatation to phytoestrogens and estrogen receptor subtypes expression in small arteries from women with coronary heart disease
    • Cruz, M.N., Agewall, S., Schenck-Gustafsson, K., Kublickiene, K., Acute dilatation to phytoestrogens and estrogen receptor subtypes expression in small arteries from women with coronary heart disease. Atherosclerosis 196 (2008), 49–58, 10.1016/j.atherosclerosis.2007.01.038.
    • (2008) Atherosclerosis , vol.196 , pp. 49-58
    • Cruz, M.N.1    Agewall, S.2    Schenck-Gustafsson, K.3    Kublickiene, K.4
  • 63
    • 84901836534 scopus 로고    scopus 로고
    • Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis
    • Davis, K.E., Carstens, E.J., Irani, B.G., Gent, L.M., Hahner, L.M., Clegg, D.J., Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis. Hormones and Behavior 66 (2014), 196–207, 10.1016/j.yhbeh.2014.02.004.
    • (2014) Hormones and Behavior , vol.66 , pp. 196-207
    • Davis, K.E.1    Carstens, E.J.2    Irani, B.G.3    Gent, L.M.4    Hahner, L.M.5    Clegg, D.J.6
  • 64
    • 84881244793 scopus 로고    scopus 로고
    • GPER mediates cardiotropic effects in spontaneously hypertensive rat hearts
    • De Francesco, E.M., Angelone, T., Pasqua, T., Pupo, M., Cerra, M.C., Maggiolini, M., GPER mediates cardiotropic effects in spontaneously hypertensive rat hearts. PLoS One, 8, 2013, e69322, 10.1371/journal.pone.0069322.
    • (2013) PLoS One , vol.8 , pp. e69322
    • De Francesco, E.M.1    Angelone, T.2    Pasqua, T.3    Pupo, M.4    Cerra, M.C.5    Maggiolini, M.6
  • 70
    • 0036838768 scopus 로고    scopus 로고
    • Protective effects of estrogen and selective estrogen receptor modulators in the brain
    • Dhandapani, K.M., Brann, D.W., Protective effects of estrogen and selective estrogen receptor modulators in the brain. Biology of Reproduction 67 (2002), 1379–1385.
    • (2002) Biology of Reproduction , vol.67 , pp. 1379-1385
    • Dhandapani, K.M.1    Brann, D.W.2
  • 71
    • 16344390950 scopus 로고    scopus 로고
    • Vascular consequences of menopause and hormone therapy: Importance of timing of treatment and type of estrogen
    • Dubey, R.K., Imthurn, B., Barton, M., Jackson, E.K., Vascular consequences of menopause and hormone therapy: Importance of timing of treatment and type of estrogen. Cardiovascular Research 66 (2005), 295–306, 10.1016/j.cardiores.2004.12.012.
    • (2005) Cardiovascular Research , vol.66 , pp. 295-306
    • Dubey, R.K.1    Imthurn, B.2    Barton, M.3    Jackson, E.K.4
  • 73
    • 21244503986 scopus 로고    scopus 로고
    • The atheroprotective effect of 17beta-estradiol depends on complex interactions in adaptive immunity
    • 167/1/267 [pii]
    • Elhage, R., Gourdy, P., Jawien, J., Brouchet, L., Castano, C., Fievet, C., Bayard, F., The atheroprotective effect of 17beta-estradiol depends on complex interactions in adaptive immunity. The American Journal of Pathology 167 (2005), 267–274 167/1/267 [pii].
    • (2005) The American Journal of Pathology , vol.167 , pp. 267-274
    • Elhage, R.1    Gourdy, P.2    Jawien, J.3    Brouchet, L.4    Castano, C.5    Fievet, C.6    Bayard, F.7
  • 74
    • 0032911668 scopus 로고    scopus 로고
    • Resveratrol inhibits MAPK activity and nuclear translocation in coronary artery smooth muscle: Reversal of endothelin-1 stimulatory effects
    • El-Mowafy, A.M., White, R.E., Resveratrol inhibits MAPK activity and nuclear translocation in coronary artery smooth muscle: Reversal of endothelin-1 stimulatory effects. FEBS Letters 451 (1999), 63–67.
    • (1999) FEBS Letters , vol.451 , pp. 63-67
    • El-Mowafy, A.M.1    White, R.E.2
  • 75
    • 78149283316 scopus 로고    scopus 로고
    • Lasofoxifene and cardiovascular events in postmenopausal women with osteoporosis: Five-year results from the postmenopausal evaluation and risk reduction with lasofoxifene (PEARL) trial
    • Ensrud, K., LaCroix, A., Thompson, J.R., Thompson, D.D., Eastell, R., Reid, D.M., Cummings, S., Lasofoxifene and cardiovascular events in postmenopausal women with osteoporosis: Five-year results from the postmenopausal evaluation and risk reduction with lasofoxifene (PEARL) trial. Circulation 122 (2010), 1716–1724, 10.1161/CIRCULATIONAHA.109.924571.
    • (2010) Circulation , vol.122 , pp. 1716-1724
    • Ensrud, K.1    LaCroix, A.2    Thompson, J.R.3    Thompson, D.D.4    Eastell, R.5    Reid, D.M.6    Cummings, S.7
  • 76
    • 84962086919 scopus 로고    scopus 로고
    • Characterisation of signalling by the endogenous GPER1 (GPR30) receptor in an embryonic mouse hippocampal cell line (mHippoE-18)
    • Evans, N.J., Bayliss, A.L., Reale, V., Evans, P.D., Characterisation of signalling by the endogenous GPER1 (GPR30) receptor in an embryonic mouse hippocampal cell line (mHippoE-18). PLoS One, 11, 2016, e0152138, 10.1371/journal.pone.0152138.
    • (2016) PLoS One , vol.11 , pp. e0152138
    • Evans, N.J.1    Bayliss, A.L.2    Reale, V.3    Evans, P.D.4
  • 78
    • 0029962414 scopus 로고    scopus 로고
    • The vascular protective effects of estrogen
    • Farhat, M.Y., Lavigne, M.C., Ramwell, P.W., The vascular protective effects of estrogen. FASEB Journal 10 (1996), 615–624.
    • (1996) FASEB Journal , vol.10 , pp. 615-624
    • Farhat, M.Y.1    Lavigne, M.C.2    Ramwell, P.W.3
  • 81
    • 0031584830 scopus 로고    scopus 로고
    • Cloning of a novel member of the G protein-coupled receptor family related to peptide receptors
    • Feng, Y., Gregor, P., Cloning of a novel member of the G protein-coupled receptor family related to peptide receptors. Biochemical and Biophysical Research Communications 231 (1997), 651–654, 10.1006/bbrc.1997.6161.
    • (1997) Biochemical and Biophysical Research Communications , vol.231 , pp. 651-654
    • Feng, Y.1    Gregor, P.2
  • 82
    • 0033780783 scopus 로고    scopus 로고
    • Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
    • Filardo, E.J., Quinn, J.A., Bland, K.I., Frackelton, A.R. Jr., Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Molecular Endocrinology 14 (2000), 1649–1660.
    • (2000) Molecular Endocrinology , vol.14 , pp. 1649-1660
    • Filardo, E.J.1    Quinn, J.A.2    Bland, K.I.3    Frackelton, A.R.4
  • 83
    • 0036140032 scopus 로고    scopus 로고
    • Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
    • Filardo, E.J., Quinn, J.A., Frackelton, A.R. Jr., Bland, K.I., Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Molecular Endocrinology 16 (2002), 70–84.
    • (2002) Molecular Endocrinology , vol.16 , pp. 70-84
    • Filardo, E.J.1    Quinn, J.A.2    Frackelton, A.R.3    Bland, K.I.4
  • 85
    • 0029449997 scopus 로고
    • Oestradiol inhibition of vascular myointimal proliferation following immune, chemical and mechanical injury
    • discussion 145–139
    • Foegh, M.L., Zhao, Y., Farhat, M., Ramwell, P.W., Oestradiol inhibition of vascular myointimal proliferation following immune, chemical and mechanical injury. Ciba Foundation Symposium 191 (1995), 139–145 discussion 145–139.
    • (1995) Ciba Foundation Symposium , vol.191 , pp. 139-145
    • Foegh, M.L.1    Zhao, Y.2    Farhat, M.3    Ramwell, P.W.4
  • 86
    • 79251498314 scopus 로고    scopus 로고
    • GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice
    • Ford, J., Hajibeigi, A., Long, M., Hahner, L., Gore, C., Hsieh, J.T., Oz, O.K., GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice. Journal of Bone and Mineral Research 26 (2011), 298–307, 10.1002/jbmr.209.
    • (2011) Journal of Bone and Mineral Research , vol.26 , pp. 298-307
    • Ford, J.1    Hajibeigi, A.2    Long, M.3    Hahner, L.4    Gore, C.5    Hsieh, J.T.6    Oz, O.K.7
  • 87
    • 0027303270 scopus 로고
    • Responses of smooth muscle cells to platelet-derived growth factor are inhibited by herbimycin-A tyrosine kinase inhibitor
    • Fujio, Y., Yamada, F., Takahashi, K., Shibata, N., Responses of smooth muscle cells to platelet-derived growth factor are inhibited by herbimycin-A tyrosine kinase inhibitor. Biochemical and Biophysical Research Communications 195 (1993), 79–83, 10.1006/bbrc.1993.2012.
    • (1993) Biochemical and Biophysical Research Communications , vol.195 , pp. 79-83
    • Fujio, Y.1    Yamada, F.2    Takahashi, K.3    Shibata, N.4
  • 88
    • 84908042418 scopus 로고    scopus 로고
    • Duelling receptors: Estrogen receptor versus mineralocorticoid receptor in the cardiovascular system
    • Fuller, P.J., Young, M.J., Duelling receptors: Estrogen receptor versus mineralocorticoid receptor in the cardiovascular system. Endocrinology 155 (2014), 4117–4119, 10.1210/en.2014-1778.
    • (2014) Endocrinology , vol.155 , pp. 4117-4119
    • Fuller, P.J.1    Young, M.J.2
  • 89
    • 0000014429 scopus 로고
    • Studies on relaxation of rabbit aorta by sodium nitrite: The basis for the proposal that acid-activatable inhibitory factor from bovine retractor penis is inorganic nitrite and the endothelium-derived relaxing factor is nitric oxide
    • P.M. Vanhoutte Raven Press New York
    • Furchgott, R.F., Studies on relaxation of rabbit aorta by sodium nitrite: The basis for the proposal that acid-activatable inhibitory factor from bovine retractor penis is inorganic nitrite and the endothelium-derived relaxing factor is nitric oxide. Vanhoutte, P.M., (eds.) Vasodilation: Vascular smooth muscle, peptides, autonomic nerves and endothelium, 1988, Raven Press, New York, 401–414.
    • (1988) Vasodilation: Vascular smooth muscle, peptides, autonomic nerves and endothelium , pp. 401-414
    • Furchgott, R.F.1
  • 90
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott, R.F., Zawadzki, J.V., The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288 (1980), 373–376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 91
    • 0037174973 scopus 로고    scopus 로고
    • Dydrogesterone does not reverse the effects of estradiol on endothelium-dependant vasodilation in postmenopausal women: A randomised clinical trial
    • Gambacciani, M., Monteleone, P., Vitale, C., Silvestri, A., Fini, M., Genazzani, A.R., Rosano, G.M., Dydrogesterone does not reverse the effects of estradiol on endothelium-dependant vasodilation in postmenopausal women: A randomised clinical trial. Maturitas 43 (2002), 117–123.
    • (2002) Maturitas , vol.43 , pp. 117-123
    • Gambacciani, M.1    Monteleone, P.2    Vitale, C.3    Silvestri, A.4    Fini, M.5    Genazzani, A.R.6    Rosano, G.M.7
  • 92
    • 84949591872 scopus 로고    scopus 로고
    • The G-protein coupled estrogen receptor, GPER: The inside and inside-out story
    • Gaudet, H.M., Cheng, S.B., Christensen, E.M., Filardo, E.J., The G-protein coupled estrogen receptor, GPER: The inside and inside-out story. Molecular and Cellular Endocrinology 418:Pt. 3 (2015), 207–219, 10.1016/j.mce.2015.07.016.
    • (2015) Molecular and Cellular Endocrinology , vol.418 , pp. 207-219
    • Gaudet, H.M.1    Cheng, S.B.2    Christensen, E.M.3    Filardo, E.J.4
  • 93
    • 0032558465 scopus 로고    scopus 로고
    • Estradiol therapy combined with progesterone and endothelium-dependent vasodilation in postmenopausal women
    • Gerhard, M., Walsh, B.W., Tawakol, A., Haley, E.A., Creager, S.J., Seely, E.W., Creager, M.A., Estradiol therapy combined with progesterone and endothelium-dependent vasodilation in postmenopausal women. Circulation 98 (1998), 1158–1163.
    • (1998) Circulation , vol.98 , pp. 1158-1163
    • Gerhard, M.1    Walsh, B.W.2    Tawakol, A.3    Haley, E.A.4    Creager, S.J.5    Seely, E.W.6    Creager, M.A.7
  • 95
    • 84959056021 scopus 로고    scopus 로고
    • Endothelial cell dysfunction and the pathobiology of atherosclerosis
    • Gimbrone, M.A. Jr., Garcia-Cardena, G., Endothelial cell dysfunction and the pathobiology of atherosclerosis. Circulation Research 118 (2016), 620–636, 10.1161/CIRCRESAHA.115.306301.
    • (2016) Circulation Research , vol.118 , pp. 620-636
    • Gimbrone, M.A.1    Garcia-Cardena, G.2
  • 97
    • 0023137661 scopus 로고
    • Alpha adrenergic responses of blood vessels of rabbits after ovariectomy and administration of 17 beta-estradiol
    • Gisclard, V., Flavahan, N.A., Vanhoutte, P.M., Alpha adrenergic responses of blood vessels of rabbits after ovariectomy and administration of 17 beta-estradiol. The Journal of Pharmacology and Experimental Therapeutics 240 (1987), 466–470.
    • (1987) The Journal of Pharmacology and Experimental Therapeutics , vol.240 , pp. 466-470
    • Gisclard, V.1    Flavahan, N.A.2    Vanhoutte, P.M.3
  • 99
    • 84855717043 scopus 로고    scopus 로고
    • Vasodilator signals from perivascular adipose tissue
    • Gollasch, M., Vasodilator signals from perivascular adipose tissue. British Journal of Pharmacology 165 (2012), 633–642, 10.1111/j.1476-5381.2011.01430.x.
    • (2012) British Journal of Pharmacology , vol.165 , pp. 633-642
    • Gollasch, M.1
  • 101
    • 0027184395 scopus 로고
    • Tamoxifen decreases the rate of proliferation of rat vascular smooth-muscle cells in culture by inducing production of transforming growth factor beta
    • Grainger, D.J., Weissberg, P.L., Metcalfe, J.C., Tamoxifen decreases the rate of proliferation of rat vascular smooth-muscle cells in culture by inducing production of transforming growth factor beta. The Biochemical Journal 294:Pt. 1 (1993), 109–112.
    • (1993) The Biochemical Journal , vol.294 , pp. 109-112
    • Grainger, D.J.1    Weissberg, P.L.2    Metcalfe, J.C.3
  • 103
    • 0022653964 scopus 로고
    • Human oestrogen receptor cDNA: Sequence, expression and homology to v-erb-A
    • Green, S., Walter, P., Kumar, V., Krust, A., Bornert, J.M., Argos, P., Chambon, P., Human oestrogen receptor cDNA: Sequence, expression and homology to v-erb-A. Nature 320 (1986), 134–139, 10.1038/320134a0.
    • (1986) Nature , vol.320 , pp. 134-139
    • Green, S.1    Walter, P.2    Kumar, V.3    Krust, A.4    Bornert, J.M.5    Argos, P.6    Chambon, P.7
  • 104
    • 0022473069 scopus 로고
    • Sequence and expression of human estrogen receptor complementary DNA
    • Greene, G.L., Gilna, P., Waterfield, M., Baker, A., Hort, Y., Shine, J., Sequence and expression of human estrogen receptor complementary DNA. Science 231 (1986), 1150–1154.
    • (1986) Science , vol.231 , pp. 1150-1154
    • Greene, G.L.1    Gilna, P.2    Waterfield, M.3    Baker, A.4    Hort, Y.5    Shine, J.6
  • 105
  • 106
    • 79953235261 scopus 로고    scopus 로고
    • GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone
    • HYPERTENSIONAHA.110.161653 [pii]
    • Gros, R., Ding, Q., Sklar, L.A., Prossnitz, E.E., Arterburn, J.B., Chorazyczewski, J., Feldman, R.D., GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone. Hypertension 57 (2011), 442–451, 10.1161/HYPERTENSIONAHA.110.161653 HYPERTENSIONAHA.110.161653 [pii].
    • (2011) Hypertension , vol.57 , pp. 442-451
    • Gros, R.1    Ding, Q.2    Sklar, L.A.3    Prossnitz, E.E.4    Arterburn, J.B.5    Chorazyczewski, J.6    Feldman, R.D.7
  • 108
    • 21244506201 scopus 로고    scopus 로고
    • Estrogen induces vascular wall dilation: Mediation through kinase signaling to nitric oxide and estrogen receptors alpha and beta
    • M501244200 [pii]
    • Guo, X., Razandi, M., Pedram, A., Kassab, G., Levin, E.R., Estrogen induces vascular wall dilation: Mediation through kinase signaling to nitric oxide and estrogen receptors alpha and beta. The Journal of Biological Chemistry 280 (2005), 19704–19710, 10.1074/jbc.M501244200 M501244200 [pii].
    • (2005) The Journal of Biological Chemistry , vol.280 , pp. 19704-19710
    • Guo, X.1    Razandi, M.2    Pedram, A.3    Kassab, G.4    Levin, E.R.5
  • 109
    • 0035657315 scopus 로고    scopus 로고
    • Combined hormone replacement therapy improves endothelial function in healthy postmenopausal women
    • Guzic-Salobir, B., Keber, I., Seljeflot, I., Arnesen, H., Vrabic, L., Combined hormone replacement therapy improves endothelial function in healthy postmenopausal women. Journal of Internal Medicine 250 (2001), 508–515.
    • (2001) Journal of Internal Medicine , vol.250 , pp. 508-515
    • Guzic-Salobir, B.1    Keber, I.2    Seljeflot, I.3    Arnesen, H.4    Vrabic, L.5
  • 110
    • 61949405394 scopus 로고    scopus 로고
    • Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity
    • CIRCRESAHA.108.190892 [pii]
    • Haas, E., Bhattacharya, I., Brailoiu, E., Damjanovic, M., Brailoiu, G.C., Gao, X., Barton, M., Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity. Circulation Research 104 (2009), 288–291, 10.1161/CIRCRESAHA.108.190892 CIRCRESAHA.108.190892 [pii].
    • (2009) Circulation Research , vol.104 , pp. 288-291
    • Haas, E.1    Bhattacharya, I.2    Brailoiu, E.3    Damjanovic, M.4    Brailoiu, G.C.5    Gao, X.6    Barton, M.7
  • 111
    • 34249321995 scopus 로고    scopus 로고
    • Differential effects of 17beta-estradiol on function and expression of estrogen receptor alpha, estrogen receptor beta, and GPR30 in arteries and veins of patients with atherosclerosis
    • Haas, E., Meyer, M.R., Schurr, U., Bhattacharya, I., Minotti, R., Nguyen, H.H., Barton, M., Differential effects of 17beta-estradiol on function and expression of estrogen receptor alpha, estrogen receptor beta, and GPR30 in arteries and veins of patients with atherosclerosis. Hypertension 49 (2007), 1358–1363.
    • (2007) Hypertension , vol.49 , pp. 1358-1363
    • Haas, E.1    Meyer, M.R.2    Schurr, U.3    Bhattacharya, I.4    Minotti, R.5    Nguyen, H.H.6    Barton, M.7
  • 112
    • 84928028211 scopus 로고    scopus 로고
    • G-protein-coupled estrogen receptor as a new therapeutic target for treating coronary artery disease
    • Han, G., White, R.E., G-protein-coupled estrogen receptor as a new therapeutic target for treating coronary artery disease. World Journal of Cardiology 6 (2014), 367–375, 10.4330/wjc.v6.i6.367.
    • (2014) World Journal of Cardiology , vol.6 , pp. 367-375
    • Han, G.1    White, R.E.2
  • 114
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson, G.K., Inflammation, atherosclerosis, and coronary artery disease. The New England Journal of Medicine 352 (2005), 1685–1695.
    • (2005) The New England Journal of Medicine , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 115
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: A double-edged sword
    • nri1882 [pii]
    • Hansson, G.K., Libby, P., The immune response in atherosclerosis: A double-edged sword. Nature Reviews Immunology 6 (2006), 508–519, 10.1038/nri1882 nri1882 [pii].
    • (2006) Nature Reviews Immunology , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 118
    • 22544482107 scopus 로고    scopus 로고
    • A G protein-coupled receptor for estrogen: The end of the search?
    • Hasbi, A., O'Dowd, B.F., George, S.R., A G protein-coupled receptor for estrogen: The end of the search?. Molecular Interventions 5 (2005), 158–161, 10.1124/mi.5.3.5.
    • (2005) Molecular Interventions , vol.5 , pp. 158-161
    • Hasbi, A.1    O'Dowd, B.F.2    George, S.R.3
  • 119
    • 0034644608 scopus 로고    scopus 로고
    • Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells
    • Haynes, M.P., Sinha, D., Russell, K.S., Collinge, M., Fulton, D., Morales-Ruiz, M., Bender, J.R., Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells. Circulation Research 87 (2000), 677–682.
    • (2000) Circulation Research , vol.87 , pp. 677-682
    • Haynes, M.P.1    Sinha, D.2    Russell, K.S.3    Collinge, M.4    Fulton, D.5    Morales-Ruiz, M.6    Bender, J.R.7
  • 120
    • 79952444246 scopus 로고    scopus 로고
    • Forecasting the future of cardiovascular disease in the United States: A policy statement from the American Heart Association
    • Heidenreich, P.A., Trogdon, J.G., Khavjou, O.A., Butler, J., Dracup, K., Ezekowitz, M.D., … Interdisciplinary Council on Quality of Care and Outcomes Research. Forecasting the future of cardiovascular disease in the United States: A policy statement from the American Heart Association. Circulation 123 (2011), 933–944, 10.1161/CIR.0b013e31820a55f5.
    • (2011) Circulation , vol.123 , pp. 933-944
    • Heidenreich, P.A.1    Trogdon, J.G.2    Khavjou, O.A.3    Butler, J.4    Dracup, K.5    Ezekowitz, M.D.6
  • 121
    • 84949254798 scopus 로고    scopus 로고
    • Impaired estrogen receptor action in the pathogenesis of the metabolic syndrome
    • Hevener, A.L., Clegg, D.J., Mauvais-Jarvis, F., Impaired estrogen receptor action in the pathogenesis of the metabolic syndrome. Molecular and Cellular Endocrinology 418:Pt 3 (2015), 306–321, 10.1016/j.mce.2015.05.020.
    • (2015) Molecular and Cellular Endocrinology , vol.418 , pp. 306-321
    • Hevener, A.L.1    Clegg, D.J.2    Mauvais-Jarvis, F.3
  • 123
    • 84964858027 scopus 로고    scopus 로고
    • What's new in estrogen receptor action in the female reproductive tract
    • Hewitt, S.C., Winuthayanon, W., Korach, K.S., What's new in estrogen receptor action in the female reproductive tract. Journal of Molecular Endocrinology 56 (2016), R55–R71, 10.1530/JME-15-0254.
    • (2016) Journal of Molecular Endocrinology , vol.56 , pp. R55-R71
    • Hewitt, S.C.1    Winuthayanon, W.2    Korach, K.S.3
  • 124
    • 77649088421 scopus 로고    scopus 로고
    • Nongenomic inhibition of coronary constriction by 17ss-estradiol, 2-hydroxyestradiol, and 2-methoxyestradiol
    • Hill, B.J., Gebre, S., Schlicker, B., Jordan, R., Necessary, S., Nongenomic inhibition of coronary constriction by 17ss-estradiol, 2-hydroxyestradiol, and 2-methoxyestradiol. Canadian Journal of Physiology and Pharmacology 88 (2010), 147–152, 10.1139/Y09-120.
    • (2010) Canadian Journal of Physiology and Pharmacology , vol.88 , pp. 147-152
    • Hill, B.J.1    Gebre, S.2    Schlicker, B.3    Jordan, R.4    Necessary, S.5
  • 125
    • 0035132187 scopus 로고    scopus 로고
    • Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in ApoE-/- mice
    • Hodgin, J.B., Krege, J.H., Reddick, R.L., Korach, K.S., Smithies, O., Maeda, N., Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in ApoE-/- mice. The Journal of Clinical Investigation 107 (2001), 333–340.
    • (2001) The Journal of Clinical Investigation , vol.107 , pp. 333-340
    • Hodgin, J.B.1    Krege, J.H.2    Reddick, R.L.3    Korach, K.S.4    Smithies, O.5    Maeda, N.6
  • 127
    • 0032547326 scopus 로고    scopus 로고
    • Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) research group
    • Hulley, S., Grady, D., Bush, T., Furberg, C., Herrington, D., Riggs, B., Vittinghoff, E., Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) research group. JAMA 280 (1998), 605–613.
    • (1998) JAMA , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Bush, T.3    Furberg, C.4    Herrington, D.5    Riggs, B.6    Vittinghoff, E.7
  • 131
    • 84863827034 scopus 로고    scopus 로고
    • Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes
    • Ikeda, Y., Tajima, S., Izawa-Ishizawa, Y., Kihira, Y., Ishizawa, K., Tomita, S., Tamaki, T., Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes. PLoS One, 7, 2012, e40465, 10.1371/journal.pone.0040465.
    • (2012) PLoS One , vol.7 , pp. e40465
    • Ikeda, Y.1    Tajima, S.2    Izawa-Ishizawa, Y.3    Kihira, Y.4    Ishizawa, K.5    Tomita, S.6    Tamaki, T.7
  • 133
    • 0026537742 scopus 로고
    • Relation between coronary risk and coronary mortality in women of the Renfrew and Paisley survey: Comparison with men
    • Isles, C.G., Hole, D.J., Hawthorne, V.M., Lever, A.F., Relation between coronary risk and coronary mortality in women of the Renfrew and Paisley survey: Comparison with men. Lancet 339 (1992), 702–706.
    • (1992) Lancet , vol.339 , pp. 702-706
    • Isles, C.G.1    Hole, D.J.2    Hawthorne, V.M.3    Lever, A.F.4
  • 134
    • 84883741018 scopus 로고    scopus 로고
    • GPER-1 agonist G1 induces vasorelaxation through activation of epidermal growth factor receptor-dependent signalling pathway
    • Jang, E.J., Seok, Y.M., Arterburn, J.B., Olatunji, L.A., Kim, I.K., GPER-1 agonist G1 induces vasorelaxation through activation of epidermal growth factor receptor-dependent signalling pathway. The Journal of Pharmacy and Pharmacology 65 (2013), 1488–1499, 10.1111/jphp.12113.
    • (2013) The Journal of Pharmacy and Pharmacology , vol.65 , pp. 1488-1499
    • Jang, E.J.1    Seok, Y.M.2    Arterburn, J.B.3    Olatunji, L.A.4    Kim, I.K.5
  • 135
    • 0015861556 scopus 로고
    • Estrogen-receptor interaction
    • Jensen, E.V., DeSombre, E.R., Estrogen-receptor interaction. Science 182 (1973), 126–134.
    • (1973) Science , vol.182 , pp. 126-134
    • Jensen, E.V.1    DeSombre, E.R.2
  • 136
    • 84857298044 scopus 로고    scopus 로고
    • A conversation with Elwood Jensen. Interview by David D. Moore
    • Jensen, E., A conversation with Elwood Jensen. Interview by David D. Moore. Annual Reviews in Physiology 74 (2014), 1–11, 10.1146/annurev-physiol-020911-153327.
    • (2014) Annual Reviews in Physiology , vol.74 , pp. 1-11
    • Jensen, E.1
  • 139
    • 78149487334 scopus 로고    scopus 로고
    • Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats
    • Jessup, J.A., Lindsey, S.H., Wang, H., Chappell, M.C., Groban, L., Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats. PLoS One, 5, 2010, e15433, 10.1371/journal.pone.0015433.
    • (2010) PLoS One , vol.5 , pp. e15433
    • Jessup, J.A.1    Lindsey, S.H.2    Wang, H.3    Chappell, M.C.4    Groban, L.5
  • 140
    • 84982792212 scopus 로고    scopus 로고
    • GPR30 promotes prostate stromal cell activation via suppression of ERα expression and its downstream signaling pathway
    • epub May 10
    • Jia, B., Gao, Y., Li, M., Shi, J., Peng, Y., Du, X., Zhang, J., GPR30 promotes prostate stromal cell activation via suppression of ERα expression and its downstream signaling pathway. Endocrinology, 2016 http://dx.doi.org/en20161035 epub May 10.
    • (2016) Endocrinology
    • Jia, B.1    Gao, Y.2    Li, M.3    Shi, J.4    Peng, Y.5    Du, X.6    Zhang, J.7
  • 141
    • 84944721260 scopus 로고    scopus 로고
    • G Protein-coupled estrogen receptor 1 mediates acute estrogen-induced cardioprotection via MEK/ERK/GSK-3 beta pathway after ischemia/reperfusion
    • Kabir, M.E., Singh, H., Lu, R., Olde, B., Leeb-Lundberg, L.M., Bopassa, J.C., G Protein-coupled estrogen receptor 1 mediates acute estrogen-induced cardioprotection via MEK/ERK/GSK-3 beta pathway after ischemia/reperfusion. PLoS One, 10, 2015, e0135988, 10.1371/journal.pone.0135988.
    • (2015) PLoS One , vol.10 , pp. e0135988
    • Kabir, M.E.1    Singh, H.2    Lu, R.3    Olde, B.4    Leeb-Lundberg, L.M.5    Bopassa, J.C.6
  • 142
    • 84868088791 scopus 로고    scopus 로고
    • Chronic activation of the G protein-coupled receptor 30 with agonist G-1 attenuates heart failure
    • Kang, S., Liu, Y., Sun, D., Zhou, C., Liu, A., Xu, C., Sun, H., Chronic activation of the G protein-coupled receptor 30 with agonist G-1 attenuates heart failure. PLoS One, 7, 2012, e48185, 10.1371/journal.pone.0048185.
    • (2012) PLoS One , vol.7 , pp. e48185
    • Kang, S.1    Liu, Y.2    Sun, D.3    Zhou, C.4    Liu, A.5    Xu, C.6    Sun, H.7
  • 144
    • 0032240121 scopus 로고    scopus 로고
    • Rapid vasomotor effects of estrogen: Men are part of the club
    • Karas, R.H., Mendelsohn, M.E., Rapid vasomotor effects of estrogen: Men are part of the club. Chest 114 (1998), 1508–1509.
    • (1998) Chest , vol.114 , pp. 1508-1509
    • Karas, R.H.1    Mendelsohn, M.E.2
  • 146
    • 84889078455 scopus 로고    scopus 로고
    • Estrogen, vascular estrogen receptor and hormone therapy in postmenopausal vascular disease
    • Khalil, R.A., Estrogen, vascular estrogen receptor and hormone therapy in postmenopausal vascular disease. Biochemical Pharmacology 86 (2013), 1627–1642, 10.1016/j.bcp.2013.09.024.
    • (2013) Biochemical Pharmacology , vol.86 , pp. 1627-1642
    • Khalil, R.A.1
  • 147
    • 84962433680 scopus 로고    scopus 로고
    • Postmenopausal hormone therapy and atherosclerosis—Time is of the essence
    • Keaney, J.F. Jr., Solomon, C.G., Postmenopausal hormone therapy and atherosclerosis—Time is of the essence. The New England Journal of Medicine 374 (2016), 1279–1280, 10.1056/NEJMe1602846.
    • (2016) The New England Journal of Medicine , vol.374 , pp. 1279-1280
    • Keaney, J.F.1    Solomon, C.G.2
  • 148
    • 0035854774 scopus 로고    scopus 로고
    • Orphan G protein-coupled receptor, GPR41, induces apoptosis via a p53/Bax pathway during ischemic hypoxia and reoxygenation
    • Kimura, M., Mizukami, Y., Miura, T., Fujimoto, K., Kobayashi, S., Matsuzaki, M., Orphan G protein-coupled receptor, GPR41, induces apoptosis via a p53/Bax pathway during ischemic hypoxia and reoxygenation. The Journal of Biological Chemistry 276 (2001), 26453–26460, 10.1074/jbc.M101289200.
    • (2001) The Journal of Biological Chemistry , vol.276 , pp. 26453-26460
    • Kimura, M.1    Mizukami, Y.2    Miura, T.3    Fujimoto, K.4    Kobayashi, S.5    Matsuzaki, M.6
  • 150
    • 0035726616 scopus 로고    scopus 로고
    • Low-dose estrogen supplementation improves vascular function in hypogonadal men
    • Komesaroff, P.A., Fullerton, M., Esler, M.D., Dart, A., Jennings, G., Sudhir, K., Low-dose estrogen supplementation improves vascular function in hypogonadal men. Hypertension 38 (2001), 1011–1016.
    • (2001) Hypertension , vol.38 , pp. 1011-1016
    • Komesaroff, P.A.1    Fullerton, M.2    Esler, M.D.3    Dart, A.4    Jennings, G.5    Sudhir, K.6
  • 151
    • 43249086430 scopus 로고    scopus 로고
    • Effects in postmenopausal women of estradiol and medroxyprogesterone alone and combined on resistance artery function and endothelial morphology and movement
    • Kublickiene, K., Fu, X.D., Svedas, E., Landgren, B.M., Genazzani, A.R., Simoncini, T., Effects in postmenopausal women of estradiol and medroxyprogesterone alone and combined on resistance artery function and endothelial morphology and movement. The Journal of Clinical Endocrinology and Metabolism 93 (2008), 1874–1883, 10.1210/jc.2007-2651.
    • (2008) The Journal of Clinical Endocrinology and Metabolism , vol.93 , pp. 1874-1883
    • Kublickiene, K.1    Fu, X.D.2    Svedas, E.3    Landgren, B.M.4    Genazzani, A.R.5    Simoncini, T.6
  • 153
    • 0031582196 scopus 로고    scopus 로고
    • A novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue
    • doi:S0014-5793(97)00278-0 [pii]
    • Kvingedal, A.M., Smeland, E.B., A novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue. FEBS Letters 407 (1997), 59–62 doi:S0014-5793(97)00278-0 [pii].
    • (1997) FEBS Letters , vol.407 , pp. 59-62
    • Kvingedal, A.M.1    Smeland, E.B.2
  • 155
    • 84964669831 scopus 로고    scopus 로고
    • Three nuclear and two membrane estrogen receptors in basal teleosts, Anguilla sp.: Identification, evolutionary history and differential expression regulation
    • (in press)
    • Lafont, A.G., Rousseau, K., Tomkiewicz, J., Dufour, S., Three nuclear and two membrane estrogen receptors in basal teleosts, Anguilla sp.: Identification, evolutionary history and differential expression regulation. General and Comparative Endocrinology, 2016, 10.1016/j.ygcen.2015.11.021 (in press).
    • (2016) General and Comparative Endocrinology
    • Lafont, A.G.1    Rousseau, K.2    Tomkiewicz, J.3    Dufour, S.4
  • 156
    • 84937979119 scopus 로고    scopus 로고
    • So! What's aging? Is cardiovascular aging a disease?
    • Lakatta, E.G., So! What's aging? Is cardiovascular aging a disease?. Journal of Molecular and Cellular Cardiology 83 (2015), 1–13, 10.1016/j.yjmcc.2015.04.005.
    • (2015) Journal of Molecular and Cellular Cardiology , vol.83 , pp. 1-13
    • Lakatta, E.G.1
  • 158
    • 84911991541 scopus 로고    scopus 로고
    • Both GPER and membrane oestrogen receptor-alpha activation protect ventricular remodelling in 17beta oestradiol-treated ovariectomized infarcted rats
    • Lee, T.M., Lin, S.Z., Chang, N.C., Both GPER and membrane oestrogen receptor-alpha activation protect ventricular remodelling in 17beta oestradiol-treated ovariectomized infarcted rats. Journal of Cellular and Molecular Medicine 18 (2014), 2454–2465, 10.1111/jcmm.12430.
    • (2014) Journal of Cellular and Molecular Medicine , vol.18 , pp. 2454-2465
    • Lee, T.M.1    Lin, S.Z.2    Chang, N.C.3
  • 159
    • 0028126021 scopus 로고
    • Regulation of serotonin-induced DNA synthesis of bovine pulmonary artery smooth muscle cells
    • Lee, S.L., Wang, W.W., Lanzillo, J.J., Fanburg, B.L., Regulation of serotonin-induced DNA synthesis of bovine pulmonary artery smooth muscle cells. The American Journal of Physiology 266 (1994), L53–L60.
    • (1994) The American Journal of Physiology , vol.266 , pp. L53-L60
    • Lee, S.L.1    Wang, W.W.2    Lanzillo, J.J.3    Fanburg, B.L.4
  • 160
    • 84879985064 scopus 로고    scopus 로고
    • G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection
    • Lenhart, P.M., Broselid, S., Barrick, C.J., Leeb-Lundberg, L.M., Caron, K.M., G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection. Journal of Molecular Endocrinology 51 (2013), 191–202, 10.1530/JME-13-0021.
    • (2013) Journal of Molecular Endocrinology , vol.51 , pp. 191-202
    • Lenhart, P.M.1    Broselid, S.2    Barrick, C.J.3    Leeb-Lundberg, L.M.4    Caron, K.M.5
  • 162
    • 84879228917 scopus 로고    scopus 로고
    • Activation of GPER induces differentiation and inhibition of coronary artery smooth muscle cell proliferation
    • Li, F., Yu, X., Szynkarski, C.K., Meng, C., Zhou, B., Barhoumi, R., Han, G., Activation of GPER induces differentiation and inhibition of coronary artery smooth muscle cell proliferation. PLoS One, 8, 2013, e64771, 10.1371/journal.pone.0064771.
    • (2013) PLoS One , vol.8 , pp. e64771
    • Li, F.1    Yu, X.2    Szynkarski, C.K.3    Meng, C.4    Zhou, B.5    Barhoumi, R.6    Han, G.7
  • 163
    • 33644872836 scopus 로고    scopus 로고
    • Inflammation and cardiovascular disease mechanisms
    • Libby, P., Inflammation and cardiovascular disease mechanisms. The American Journal of Clinical Nutrition 83 (2006), 456S–460S.
    • (2006) The American Journal of Clinical Nutrition , vol.83 , pp. 456S-460S
    • Libby, P.1
  • 164
    • 84881223424 scopus 로고    scopus 로고
    • Collagenases and cracks in the plaque
    • Libby, P., Collagenases and cracks in the plaque. The Journal of Clinical Investigation 123 (2013), 3201–3203, 10.1172/JCI67526.
    • (2013) The Journal of Clinical Investigation , vol.123 , pp. 3201-3203
    • Libby, P.1
  • 165
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby, P., Ridker, P.M., Maseri, A., Inflammation and atherosclerosis. Circulation 105 (2002), 1135–1143.
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 167
    • 0033311155 scopus 로고    scopus 로고
    • The effect of hormonal replacement therapy on the vascular reactivity and endothelial function of healthy individuals and individuals with type 2 diabetes
    • Lim, S.C., Caballero, A.E., Arora, S., Smakowski, P., Bashoff, E.M., Brown, F.M., Veves, A., The effect of hormonal replacement therapy on the vascular reactivity and endothelial function of healthy individuals and individuals with type 2 diabetes. The Journal of Clinical Endocrinology and Metabolism 84 (1999), 4159–4164, 10.1210/jcem.84.11.6160.
    • (1999) The Journal of Clinical Endocrinology and Metabolism , vol.84 , pp. 4159-4164
    • Lim, S.C.1    Caballero, A.E.2    Arora, S.3    Smakowski, P.4    Bashoff, E.M.5    Brown, F.M.6    Veves, A.7
  • 168
    • 79957735539 scopus 로고    scopus 로고
    • Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat
    • Lindsey, S.H., Carver, K.A., Prossnitz, E.R., Chappell, M.C., Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat. Journal of Cardiovascular Pharmacology, 2011, 10.1097/FJC.0b013e3182135f1c.
    • (2011) Journal of Cardiovascular Pharmacology
    • Lindsey, S.H.1    Carver, K.A.2    Prossnitz, E.R.3    Chappell, M.C.4
  • 169
    • 67651177687 scopus 로고    scopus 로고
    • Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats
    • Lindsey, S.H., Cohen, J.A., Brosnihan, K.B., Gallagher, P.E., Chappell, M.C., Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats. Endocrinology 150 (2009), 3753–3758.
    • (2009) Endocrinology , vol.150 , pp. 3753-3758
    • Lindsey, S.H.1    Cohen, J.A.2    Brosnihan, K.B.3    Gallagher, P.E.4    Chappell, M.C.5
  • 170
    • 84895519872 scopus 로고    scopus 로고
    • Vasodilation by GPER in mesenteric arteries involves both endothelial nitric oxide and smooth muscle cAMP signaling
    • Lindsey, S.H., Liu, L., Chappell, M.C., Vasodilation by GPER in mesenteric arteries involves both endothelial nitric oxide and smooth muscle cAMP signaling. Steroids 81 (2014), 99–102, 10.1016/j.steroids.2013.10.017.
    • (2014) Steroids , vol.81 , pp. 99-102
    • Lindsey, S.H.1    Liu, L.2    Chappell, M.C.3
  • 171
    • 80053478893 scopus 로고    scopus 로고
    • Estrogen receptor GPR30 reduces oxidative stress and proteinuria in the salt-sensitive female mRen2.Lewis rat
    • Lindsey, S.H., Yamaleyeva, L.M., Brosnihan, K.B., Gallagher, P.E., Chappell, M.C., Estrogen receptor GPR30 reduces oxidative stress and proteinuria in the salt-sensitive female mRen2.Lewis rat. Hypertension 58 (2011), 665–671, 10.1161/HYPERTENSIONAHA.111.175174.
    • (2011) Hypertension , vol.58 , pp. 665-671
    • Lindsey, S.H.1    Yamaleyeva, L.M.2    Brosnihan, K.B.3    Gallagher, P.E.4    Chappell, M.C.5
  • 173
    • 84878659317 scopus 로고    scopus 로고
    • Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes
    • Liu, S., Kilic, G., Meyers, M.S., Navarro, G., Wang, Y., Oberholzer, J., Mauvais-Jarvis, F., Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes. Diabetologia 56 (2013), 370–381, 10.1007/s00125-012-2764-1.
    • (2013) Diabetologia , vol.56 , pp. 370-381
    • Liu, S.1    Kilic, G.2    Meyers, M.S.3    Navarro, G.4    Wang, Y.5    Oberholzer, J.6    Mauvais-Jarvis, F.7
  • 174
    • 0037005743 scopus 로고    scopus 로고
    • Green tea polyphenols inhibit human vascular smooth muscle cell proliferation stimulated by native low-density lipoprotein
    • Locher, R., Emmanuele, L., Suter, P.M., Vetter, W., Barton, M., Green tea polyphenols inhibit human vascular smooth muscle cell proliferation stimulated by native low-density lipoprotein. European Journal of Pharmacology 434 (2002), 1–7.
    • (2002) European Journal of Pharmacology , vol.434 , pp. 1-7
    • Locher, R.1    Emmanuele, L.2    Suter, P.M.3    Vetter, W.4    Barton, M.5
  • 176
    • 3142550827 scopus 로고    scopus 로고
    • Antidiabetic actions of estrogen: Insight from human and genetic mouse models
    • Louet, J.F., LeMay, C., Mauvais-Jarvis, F., Antidiabetic actions of estrogen: Insight from human and genetic mouse models. Current Atherosclerosis Reports 6 (2004), 180–185.
    • (2004) Current Atherosclerosis Reports , vol.6 , pp. 180-185
    • Louet, J.F.1    LeMay, C.2    Mauvais-Jarvis, F.3
  • 177
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
    • Lozano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, V.,.. Memish, Z.A., Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 380 (2012), 2095–2128, 10.1016/S0140-6736(12)61728-0.
    • (2012) Lancet , vol.380 , pp. 2095-2128
    • Lozano, R.1    Naghavi, M.2    Foreman, K.3    Lim, S.4    Shibuya, K.5    Aboyans, V.6    Memish, Z.A.7
  • 178
    • 84971350913 scopus 로고    scopus 로고
    • Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues
    • ra53
    • Madak-Erdogan, Z., Kim, S.H., Gong, P., Zhao, Y.C., Zhang, H., Chambliss, K.L.,.. Katzenellenbogen, B.S., Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues. Science Signaling, 9, 2016, 10.1126/scisignal.aad8170 ra53.
    • (2016) Science Signaling , vol.9
    • Madak-Erdogan, Z.1    Kim, S.H.2    Gong, P.3    Zhao, Y.C.4    Zhang, H.5    Chambliss, K.L.6    Katzenellenbogen, B.S.7
  • 180
    • 59649122739 scopus 로고    scopus 로고
    • Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice
    • en.2008-0623 [pii]
    • Mårtensson, U.E., Salehi, S.A., Windahl, S., Gomez, M.F., Sward, K., Daszkiewicz-Nilsson, J., Leeb-Lundberg, L.M., Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice. Endocrinology 150 (2009), 687–698, 10.1210/en.2008-0623 en.2008-0623 [pii].
    • (2009) Endocrinology , vol.150 , pp. 687-698
    • Mårtensson, U.E.1    Salehi, S.A.2    Windahl, S.3    Gomez, M.F.4    Sward, K.5    Daszkiewicz-Nilsson, J.6    Leeb-Lundberg, L.M.7
  • 181
    • 84947211118 scopus 로고    scopus 로고
    • Adaptive increases in expression and vasodilator activity of estrogen receptor subtypes in a blood vessel-specific pattern during pregnancy
    • Mata, K.M., Li, W., Reslan, O.M., Siddiqui, W.T., Opsasnick, L.A., Khalil, R.A., Adaptive increases in expression and vasodilator activity of estrogen receptor subtypes in a blood vessel-specific pattern during pregnancy. American Journal of Physiology. Heart and Circulatory Physiology 309 (2015), H1679–H1696, 10.1152/ajpheart.00532.2015.
    • (2015) American Journal of Physiology. Heart and Circulatory Physiology , vol.309 , pp. H1679-H1696
    • Mata, K.M.1    Li, W.2    Reslan, O.M.3    Siddiqui, W.T.4    Opsasnick, L.A.5    Khalil, R.A.6
  • 182
    • 1642332240 scopus 로고    scopus 로고
    • Estrogen signaling: A subtle balance between ER alpha and ER beta
    • Matthews, J., Gustafsson, J.A., Estrogen signaling: A subtle balance between ER alpha and ER beta. Molecular Interventions 3 (2003), 281–292.
    • (2003) Molecular Interventions , vol.3 , pp. 281-292
    • Matthews, J.1    Gustafsson, J.A.2
  • 183
    • 84878632677 scopus 로고    scopus 로고
    • The role of estrogens in control of energy balance and glucose homeostasis
    • Mauvais-Jarvis, F., Clegg, D.J., Hevener, A.L., The role of estrogens in control of energy balance and glucose homeostasis. Endocrine Reviews 34 (2013), 309–338, 10.1210/er.2012-1055.
    • (2013) Endocrine Reviews , vol.34 , pp. 309-338
    • Mauvais-Jarvis, F.1    Clegg, D.J.2    Hevener, A.L.3
  • 184
    • 84876883246 scopus 로고    scopus 로고
    • The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice
    • Maximov, P.Y., Lee, T.M., Jordan, V.C., The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice. Current Clinical Pharmacology 8 (2013), 135–155.
    • (2013) Current Clinical Pharmacology , vol.8 , pp. 135-155
    • Maximov, P.Y.1    Lee, T.M.2    Jordan, V.C.3
  • 185
    • 84919709667 scopus 로고    scopus 로고
    • Estrogen receptor subtypes mediate distinct microvascular dilation and reduction in [Ca2 +]I in mesenteric microvessels of female rat
    • Mazzuca, M.Q., Mata, K.M., Li, W., Rangan, S.S., Khalil, R.A., Estrogen receptor subtypes mediate distinct microvascular dilation and reduction in [Ca2 +]I in mesenteric microvessels of female rat. The Journal of Pharmacology and Experimental Therapeutics 352 (2015), 291–304, 10.1124/jpet.114.219865.
    • (2015) The Journal of Pharmacology and Experimental Therapeutics , vol.352 , pp. 291-304
    • Mazzuca, M.Q.1    Mata, K.M.2    Li, W.3    Rangan, S.S.4    Khalil, R.A.5
  • 186
    • 84993271014 scopus 로고    scopus 로고
    • Cloning of novel IL8-related receptors from human hepatic tissue: Human IL8-related receptor (DRY12) mRNA, complete codons
    • Submitted June 1996 to the EMBL/GenBank/DDBJ databases. Genbank accession code U58828
    • McCoy, R.L., Perlemutter, D.H., Cloning of novel IL8-related receptors from human hepatic tissue: Human IL8-related receptor (DRY12) mRNA, complete codons. 1996 Submitted June 1996 to the EMBL/GenBank/DDBJ databases. Genbank accession code U58828.
    • (1996)
    • McCoy, R.L.1    Perlemutter, D.H.2
  • 188
    • 84959258350 scopus 로고    scopus 로고
    • Preventing and experiencing ischemic heart disease as a woman: State of the science—A scientific statement from the American Heart Association
    • McSweeney, J.C., Rosenfeld, A.G., Abel, W.M., Braun, L.T., Burke, L.E., Daugherty, S.L., on behalf of the American Heart Association Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, Council on Hypertension, Council on Lifestyle and Cardiometabolic Health, and Council on Quality of Care and Outcomes Research. Preventing and experiencing ischemic heart disease as a woman: State of the science—A scientific statement from the American Heart Association. Circulation 133 (2016), 1302–1331, 10.1161/CIR.0000000000000381.
    • (2016) Circulation , vol.133 , pp. 1302-1331
    • McSweeney, J.C.1    Rosenfeld, A.G.2    Abel, W.M.3    Braun, L.T.4    Burke, L.E.5    Daugherty, S.L.6
  • 189
    • 84954342002 scopus 로고    scopus 로고
    • The expanding complexity of estrogen receptor signaling in the cardiovascular system
    • Menazza, S., Murphy, E., The expanding complexity of estrogen receptor signaling in the cardiovascular system. Circulation Research 118 (2016), 994–1007.
    • (2016) Circulation Research , vol.118 , pp. 994-1007
    • Menazza, S.1    Murphy, E.2
  • 190
    • 0033542402 scopus 로고    scopus 로고
    • The protective effects of estrogen on the cardiovascular system
    • Mendelsohn, M.E., Karas, R.H., The protective effects of estrogen on the cardiovascular system. The New England Journal of Medicine 340 (1999), 1801–1811.
    • (1999) The New England Journal of Medicine , vol.340 , pp. 1801-1811
    • Mendelsohn, M.E.1    Karas, R.H.2
  • 191
    • 20444398494 scopus 로고    scopus 로고
    • Molecular and cellular basis of cardiovascular gender differences
    • Mendelsohn, M.E., Karas, R.H., Molecular and cellular basis of cardiovascular gender differences. Science 308 (2005), 1583–1587.
    • (2005) Science , vol.308 , pp. 1583-1587
    • Mendelsohn, M.E.1    Karas, R.H.2
  • 192
    • 84889099777 scopus 로고    scopus 로고
    • Vasoactive effects of prostaglandins from the perivascular fat of mesenteric resistance arteries in WKY and SHROB rats
    • Mendizabal, Y., Llorens, S., Nava, E., Vasoactive effects of prostaglandins from the perivascular fat of mesenteric resistance arteries in WKY and SHROB rats. Life Sciences 93 (2013), 1023–1032, 10.1016/j.lfs.2013.10.021.
    • (2013) Life Sciences , vol.93 , pp. 1023-1032
    • Mendizabal, Y.1    Llorens, S.2    Nava, E.3
  • 193
    • 33646491436 scopus 로고    scopus 로고
    • Past oral contraceptive use and angiographic coronary artery disease in postmenopausal women: Data from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation
    • Merz, C.N., Johnson, B.D., Berga, S., Braunstein, G., Reis, S.E., Bittner, V., Past oral contraceptive use and angiographic coronary artery disease in postmenopausal women: Data from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation. Fertility and Sterility 85 (2006), 1425–1431.
    • (2006) Fertility and Sterility , vol.85 , pp. 1425-1431
    • Merz, C.N.1    Johnson, B.D.2    Berga, S.3    Braunstein, G.4    Reis, S.E.5    Bittner, V.6
  • 194
    • 84856083587 scopus 로고    scopus 로고
    • Deletion of G protein-coupled estrogen receptor increases endothelial vasoconstriction
    • Meyer, M.R., Amann, K., Field, A.S., Hu, C., Hathaway, H.J., Kanagy, N.L., Prossnitz, E.R., Deletion of G protein-coupled estrogen receptor increases endothelial vasoconstriction. Hypertension 59 (2012), 507–512, 10.1161/HYPERTENSIONAHA.111.184606.
    • (2012) Hypertension , vol.59 , pp. 507-512
    • Meyer, M.R.1    Amann, K.2    Field, A.S.3    Hu, C.4    Hathaway, H.J.5    Kanagy, N.L.6    Prossnitz, E.R.7
  • 195
    • 77954544185 scopus 로고    scopus 로고
    • Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780
    • Meyer, M.R., Baretella, O., Prossnitz, E.R., Barton, M., Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780. Pharmacology 86 (2010), 58–64.
    • (2010) Pharmacology , vol.86 , pp. 58-64
    • Meyer, M.R.1    Baretella, O.2    Prossnitz, E.R.3    Barton, M.4
  • 196
    • 68949131242 scopus 로고    scopus 로고
    • ERα, ERβ, and gpER: Novel aspects of oestrogen receptor signalling in atherosclerosis
    • Meyer, M.R., Barton, M., ERα, ERβ, and gpER: Novel aspects of oestrogen receptor signalling in atherosclerosis. Cardiovascular Research 83 (2009), 605–610, 10.1093/cvr/cvp187.
    • (2009) Cardiovascular Research , vol.83 , pp. 605-610
    • Meyer, M.R.1    Barton, M.2
  • 197
    • 80051668223 scopus 로고    scopus 로고
    • Obesity, insulin resistance and diabetes: Sex differences and role of oestrogen receptors
    • Meyer, M.R., Clegg, D.J., Prossnitz, E.R., Barton, M., Obesity, insulin resistance and diabetes: Sex differences and role of oestrogen receptors. Acta Physiologica (Oxford, England) 203 (2011), 259–269, 10.1111/j.1748-1716.2010.02237.x.
    • (2011) Acta Physiologica (Oxford, England) , vol.203 , pp. 259-269
    • Meyer, M.R.1    Clegg, D.J.2    Prossnitz, E.R.3    Barton, M.4
  • 198
    • 84863990545 scopus 로고    scopus 로고
    • GPER regulates endothelin-dependent vascular tone and intracellular calcium
    • Meyer, M.R., Field, A.S., Kanagy, N.L., Barton, M., Prossnitz, E.R., GPER regulates endothelin-dependent vascular tone and intracellular calcium. Life Sciences 91 (2012), 623–627, 10.1016/j.lfs.2012.01.007.
    • (2012) Life Sciences , vol.91 , pp. 623-627
    • Meyer, M.R.1    Field, A.S.2    Kanagy, N.L.3    Barton, M.4    Prossnitz, E.R.5
  • 199
    • 84892963105 scopus 로고    scopus 로고
    • Regulation of vascular smooth muscle tone by adipose-derived contracting factor
    • Meyer, M.R., Fredette, N.C., Barton, M., Prossnitz, E.R., Regulation of vascular smooth muscle tone by adipose-derived contracting factor. PLoS One, 8, 2013, e79245, 10.1371/journal.pone.0079245.
    • (2013) PLoS One , vol.8 , pp. e79245
    • Meyer, M.R.1    Fredette, N.C.2    Barton, M.3    Prossnitz, E.R.4
  • 200
    • 84944597732 scopus 로고    scopus 로고
    • G protein-coupled estrogen receptor inhibits vascular prostanoid production and activity
    • Meyer, M.R., Fredette, N.C., Barton, M., Prossnitz, E.R., G protein-coupled estrogen receptor inhibits vascular prostanoid production and activity. The Journal of Endocrinology 227 (2015), 61–69, 10.1530/JOE-15-0257.
    • (2015) The Journal of Endocrinology , vol.227 , pp. 61-69
    • Meyer, M.R.1    Fredette, N.C.2    Barton, M.3    Prossnitz, E.R.4
  • 201
    • 84931428688 scopus 로고    scopus 로고
    • G protein-coupled estrogen receptor protects from atherosclerosis
    • Erratum in: Scientific Reports, 7565 (2015) 13510
    • Meyer, M.R., Fredette, N.C., Howard, T., Hu, C., Ramesh, C., Daniel, C., Prossnitz, E.R., G protein-coupled estrogen receptor protects from atherosclerosis. Scientific Reports, 4, 2014, 7564 Erratum in: Scientific Reports, 7565 (2015) 13510.
    • (2014) Scientific Reports , vol.4 , pp. 7564
    • Meyer, M.R.1    Fredette, N.C.2    Howard, T.3    Hu, C.4    Ramesh, C.5    Daniel, C.6    Prossnitz, E.R.7
  • 202
    • 84959043030 scopus 로고    scopus 로고
    • GPER is required for the age-dependent upregulation of the myocardial endothelin system
    • Meyer, M.R., Fredette, N.C., Sharma, G., Barton, M., Prossnitz, E.R., GPER is required for the age-dependent upregulation of the myocardial endothelin system. Life Sciences, 2016, 10.1016/j.lfs.2016.02.041.
    • (2016) Life Sciences
    • Meyer, M.R.1    Fredette, N.C.2    Sharma, G.3    Barton, M.4    Prossnitz, E.R.5
  • 203
    • 33744991090 scopus 로고    scopus 로고
    • Gender differences of cardiovascular disease: New perspectives for estrogen receptor signaling
    • Meyer, M.R., Haas, E., Barton, M., Gender differences of cardiovascular disease: New perspectives for estrogen receptor signaling. Hypertension 47 (2006), 1019–1026.
    • (2006) Hypertension , vol.47 , pp. 1019-1026
    • Meyer, M.R.1    Haas, E.2    Barton, M.3
  • 204
    • 41449088376 scopus 로고    scopus 로고
    • Need for research on estrogen receptor function: Importance for postmenopausal hormone therapy and atherosclerosis
    • Meyer, M.R., Haas, E., Barton, M., Need for research on estrogen receptor function: Importance for postmenopausal hormone therapy and atherosclerosis. Gender Medicine 5:Suppl. A (2008), S19–S33.
    • (2008) Gender Medicine , vol.5 , pp. S19-S33
    • Meyer, M.R.1    Haas, E.2    Barton, M.3
  • 206
    • 80051781308 scopus 로고    scopus 로고
    • The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function
    • S1537-1891(11)00064-4 [pii]
    • Meyer, M.R., Prossnitz, E.R., Barton, M., The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function. Vascular Pharmacology 55 (2011), 17–25, 10.1016/j.vph.2011.06.003 S1537-1891(11)00064-4 [pii].
    • (2011) Vascular Pharmacology , vol.55 , pp. 17-25
    • Meyer, M.R.1    Prossnitz, E.R.2    Barton, M.3
  • 207
    • 0035935731 scopus 로고    scopus 로고
    • Estrogen receptor-beta potency-selective ligands: Structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues
    • Meyers, M.J., Sun, J., Carlson, K.E., Marriner, G.A., Katzenellenbogen, B.S., Katzenellenbogen, J.A., Estrogen receptor-beta potency-selective ligands: Structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. Journal of Medicinal Chemistry 44 (2001), 4230–4251.
    • (2001) Journal of Medicinal Chemistry , vol.44 , pp. 4230-4251
    • Meyers, M.J.1    Sun, J.2    Carlson, K.E.3    Marriner, G.A.4    Katzenellenbogen, B.S.5    Katzenellenbogen, J.A.6
  • 208
    • 46949109892 scopus 로고    scopus 로고
    • Vascular actions of estrogens: Functional implications
    • Miller, V.M., Duckles, S.P., Vascular actions of estrogens: Functional implications. Pharmacological Reviews 60 (2008), 210–241.
    • (2008) Pharmacological Reviews , vol.60 , pp. 210-241
    • Miller, V.M.1    Duckles, S.P.2
  • 209
    • 0025326705 scopus 로고
    • 17 beta-Estradiol augments endothelium-dependent contractions to arachidonic acid in rabbit aorta
    • Miller, V.M., Vanhoutte, P.M., 17 beta-Estradiol augments endothelium-dependent contractions to arachidonic acid in rabbit aorta. The American Journal of Physiology 258 (1990), R1502–R1507.
    • (1990) The American Journal of Physiology , vol.258 , pp. R1502-R1507
    • Miller, V.M.1    Vanhoutte, P.M.2
  • 210
    • 34247565156 scopus 로고    scopus 로고
    • Aged rats lose vasoprotective and anti-inflammatory actions of estrogen in injured arteries
    • Miller, A.P., Xing, D., Feng, W., Fintel, M., Chen, Y.F., Oparil, S., Aged rats lose vasoprotective and anti-inflammatory actions of estrogen in injured arteries. Menopause 14 (2007), 251–260.
    • (2007) Menopause , vol.14 , pp. 251-260
    • Miller, A.P.1    Xing, D.2    Feng, W.3    Fintel, M.4    Chen, Y.F.5    Oparil, S.6
  • 211
    • 0034000025 scopus 로고    scopus 로고
    • Influence of the menstrual cycle on sympathetic activity, baroreflex sensitivity, and vascular transduction in young women
    • Minson, C.T., Halliwill, J.R., Young, T.M., Joyner, M.J., Influence of the menstrual cycle on sympathetic activity, baroreflex sensitivity, and vascular transduction in young women. Circulation 101 (2000), 862–868.
    • (2000) Circulation , vol.101 , pp. 862-868
    • Minson, C.T.1    Halliwill, J.R.2    Young, T.M.3    Joyner, M.J.4
  • 212
    • 0033916480 scopus 로고    scopus 로고
    • Resveratrol inhibits AGEs-induced proliferation and collagen synthesis activity in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats
    • Mizutani, K., Ikeda, K., Yamori, Y., Resveratrol inhibits AGEs-induced proliferation and collagen synthesis activity in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats. Biochemical and Biophysical Research Communications 274 (2000), 61–67, 10.1006/bbrc.2000.3097.
    • (2000) Biochemical and Biophysical Research Communications , vol.274 , pp. 61-67
    • Mizutani, K.1    Ikeda, K.2    Yamori, Y.3
  • 214
    • 0030593681 scopus 로고    scopus 로고
    • ER beta: Identification and characterization of a novel human estrogen receptor
    • Mosselman, S., Polman, J., Dijkema, R., ER beta: Identification and characterization of a novel human estrogen receptor. FEBS Letters 392 (1996), 49–53.
    • (1996) FEBS Letters , vol.392 , pp. 49-53
    • Mosselman, S.1    Polman, J.2    Dijkema, R.3
  • 215
    • 84897144066 scopus 로고    scopus 로고
    • Effect of prior oophorectomy on changes in bone mineral density and carotid artery intima-media thickness in postmenopausal women
    • Mucowski, S.J., Mack, W.J., Shoupe, D., Kono, N., Paulson, R., Hodis, H.N., Effect of prior oophorectomy on changes in bone mineral density and carotid artery intima-media thickness in postmenopausal women. Fertility and Sterility 101 (2014), 1117–1122, 10.1016/j.fertnstert.2013.12.055.
    • (2014) Fertility and Sterility , vol.101 , pp. 1117-1122
    • Mucowski, S.J.1    Mack, W.J.2    Shoupe, D.3    Kono, N.4    Paulson, R.5    Hodis, H.N.6
  • 216
    • 0027489379 scopus 로고
    • Endothelium independent relaxation of human coronary arteries by 17 beta-oestradiol in vitro
    • Mügge, A., Riedel, M., Barton, M., Kuhn, M., Lichtlen, P.R., Endothelium independent relaxation of human coronary arteries by 17 beta-oestradiol in vitro. Cardiovascular Research 27 (1993), 1939–1942.
    • (1993) Cardiovascular Research , vol.27 , pp. 1939-1942
    • Mügge, A.1    Riedel, M.2    Barton, M.3    Kuhn, M.4    Lichtlen, P.R.5
  • 217
    • 84975514187 scopus 로고
    • Estrogen dilates human coronary arteries in vitro by an increase in cyclic GMP and cyclic AMP smooth muscle content
    • Mügge, A., Riedel, M., Barton, M., Kuhn, M., Lichtlen, P.R., Estrogen dilates human coronary arteries in vitro by an increase in cyclic GMP and cyclic AMP smooth muscle content. European Heart Journal, 14, 1993, 16.
    • (1993) European Heart Journal , vol.14 , pp. 16
    • Mügge, A.1    Riedel, M.2    Barton, M.3    Kuhn, M.4    Lichtlen, P.R.5
  • 218
    • 0037133622 scopus 로고    scopus 로고
    • Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: Implications in atherosclerosis
    • Mukherjee, T.K., Dinh, H., Chaudhuri, G., Nathan, L., Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: Implications in atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America 99 (2002), 4055–4060, 10.1073/pnas.052703199.
    • (2002) Proceedings of the National Academy of Sciences of the United States of America , vol.99 , pp. 4055-4060
    • Mukherjee, T.K.1    Dinh, H.2    Chaudhuri, G.3    Nathan, L.4
  • 219
    • 84876284004 scopus 로고    scopus 로고
    • G protein-coupled estrogen receptor agonist improves cerebral microvascular function after hypoxia/reoxygenation injury in male and female rats
    • Murata, T., Dietrich, H.H., Xiang, C., Dacey, R.G. Jr., G protein-coupled estrogen receptor agonist improves cerebral microvascular function after hypoxia/reoxygenation injury in male and female rats. Stroke 44 (2013), 779–785, 10.1161/STROKEAHA.112.678177.
    • (2013) Stroke , vol.44 , pp. 779-785
    • Murata, T.1    Dietrich, H.H.2    Xiang, C.3    Dacey, R.G.4
  • 220
    • 67349253060 scopus 로고    scopus 로고
    • The pancreatic beta-cell as a target of estrogens and xenoestrogens: Implications for blood glucose homeostasis and diabetes
    • S0303-7207(09)00150-6 [pii]
    • Nadal, A., Alonso-Magdalena, P., Soriano, S., Quesada, I., Ropero, A.B., The pancreatic beta-cell as a target of estrogens and xenoestrogens: Implications for blood glucose homeostasis and diabetes. Molecular and Cellular Endocrinology 304 (2009), 63–68, 10.1016/j.mce.2009.02.016 S0303-7207(09)00150-6 [pii].
    • (2009) Molecular and Cellular Endocrinology , vol.304 , pp. 63-68
    • Nadal, A.1    Alonso-Magdalena, P.2    Soriano, S.3    Quesada, I.4    Ropero, A.B.5
  • 222
  • 223
    • 84962949589 scopus 로고    scopus 로고
    • Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants
    • Erratum in: Lancet, 2016, 387, 1998
    • NCD Risk Factor Collaboration (NCD-RisC), Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet 387 (2016), 1377–1396, 10.1016/S0140-6736(16)30054-X Erratum in: Lancet, 2016, 387, 1998.
    • (2016) Lancet , vol.387 , pp. 1377-1396
    • NCD Risk Factor Collaboration (NCD-RisC)1
  • 224
    • 0032436822 scopus 로고    scopus 로고
    • Estrogen induces nitric oxide-mediated vasodilation of human mammary arteries in vitro
    • Nechmad, A., Merin, G., Schwalb, H., Shimon, D.V., Borman, J.B., Milgalter, E., Mosseri, M., Estrogen induces nitric oxide-mediated vasodilation of human mammary arteries in vitro. Nitric Oxide 2 (1998), 460–466, 10.1006/niox.1998.0202.
    • (1998) Nitric Oxide , vol.2 , pp. 460-466
    • Nechmad, A.1    Merin, G.2    Schwalb, H.3    Shimon, D.V.4    Borman, J.B.5    Milgalter, E.6    Mosseri, M.7
  • 225
    • 84906882822 scopus 로고    scopus 로고
    • Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: A systematic analysis for the Global Burden of Disease Study 2013
    • Ng, M., Fleming, T., Robinson, M., Thomson, B., Graetz, N., Margono, C., Gakidou, E., Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet 384 (2014), 766–781, 10.1016/S0140-6736(14)60460-8.
    • (2014) Lancet , vol.384 , pp. 766-781
    • Ng, M.1    Fleming, T.2    Robinson, M.3    Thomson, B.4    Graetz, N.5    Margono, C.6    Gakidou, E.7
  • 227
    • 0032518399 scopus 로고    scopus 로고
    • Discovery of three novel G-protein-coupled receptor genes
    • S0888-7543(98)95095-9 [pii]
    • O'Dowd, B.F., Nguyen, T., Marchese, A., Cheng, R., Lynch, K.R., Heng, H.H., George, S.R., Discovery of three novel G-protein-coupled receptor genes. Genomics 47 (1998), 310–313, 10.1006/geno.1998.5095 S0888-7543(98)95095-9 [pii].
    • (1998) Genomics , vol.47 , pp. 310-313
    • O'Dowd, B.F.1    Nguyen, T.2    Marchese, A.3    Cheng, R.4    Lynch, K.R.5    Heng, H.H.6    George, S.R.7
  • 228
    • 80055004075 scopus 로고    scopus 로고
    • Perivascular visceral adipose tissue induces atherosclerosis in apolipoprotein E deficient mice
    • Ohman, M.K., Luo, W., Wang, H., Guo, C., Abdallah, W., Russo, H.M., Eitzman, D.T., Perivascular visceral adipose tissue induces atherosclerosis in apolipoprotein E deficient mice. Atherosclerosis 219 (2011), 33–39, 10.1016/j.atherosclerosis.2011.07.012.
    • (2011) Atherosclerosis , vol.219 , pp. 33-39
    • Ohman, M.K.1    Luo, W.2    Wang, H.3    Guo, C.4    Abdallah, W.5    Russo, H.M.6    Eitzman, D.T.7
  • 231
    • 84879766720 scopus 로고    scopus 로고
    • Perivascular adipose tissue potentiates contraction of coronary vascular smooth muscle: Influence of obesity
    • Owen, M.K., Witzmann, F.A., McKenney, M.L., Lai, X., Berwick, Z.C., Moberly, S.P., Tune, J.D., Perivascular adipose tissue potentiates contraction of coronary vascular smooth muscle: Influence of obesity. Circulation 128 (2013), 9–18, 10.1161/CIRCULATIONAHA.112.001238.
    • (2013) Circulation , vol.128 , pp. 9-18
    • Owen, M.K.1    Witzmann, F.A.2    McKenney, M.L.3    Lai, X.4    Berwick, Z.C.5    Moberly, S.P.6    Tune, J.D.7
  • 232
    • 0001471444 scopus 로고    scopus 로고
    • Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues
    • Owman, C., Blay, P., Nilsson, C., Lolait, S.J., Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues. Biochemical and Biophysical Research Communications 228 (1996), 285–292.
    • (1996) Biochemical and Biophysical Research Communications , vol.228 , pp. 285-292
    • Owman, C.1    Blay, P.2    Nilsson, C.3    Lolait, S.J.4
  • 233
    • 84957612468 scopus 로고    scopus 로고
    • Estrogen anti-inflammatory activity on human monocytes is mediated through cross-talk between estrogen receptor ERalpha36 and GPR30/GPER1
    • Pelekanou, V., Kampa, M., Kiagiadaki, F., Deli, A., Theodoropoulos, P., Agrogiannis, G., Notas, G., Estrogen anti-inflammatory activity on human monocytes is mediated through cross-talk between estrogen receptor ERalpha36 and GPR30/GPER1. Journal of Leukocyte Biology 99 (2016), 333–347, 10.1189/jlb.3A0914-430RR.
    • (2016) Journal of Leukocyte Biology , vol.99 , pp. 333-347
    • Pelekanou, V.1    Kampa, M.2    Kiagiadaki, F.3    Deli, A.4    Theodoropoulos, P.5    Agrogiannis, G.6    Notas, G.7
  • 237
    • 84931399806 scopus 로고    scopus 로고
    • International Union of Basic and Clinical Pharmacology. XCVII. G protein-coupled estrogen receptor (GPER) and its pharmacologic modulators
    • Prossnitz, E.R., Arterburn, J.B., International Union of Basic and Clinical Pharmacology. XCVII. G protein-coupled estrogen receptor (GPER) and its pharmacologic modulators. Pharmacological Reviews 67 (2015), 505–540.
    • (2015) Pharmacological Reviews , vol.67 , pp. 505-540
    • Prossnitz, E.R.1    Arterburn, J.B.2
  • 238
    • 69749110749 scopus 로고    scopus 로고
    • Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER
    • Prossnitz, E.R., Barton, M., Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER. Prostaglandins & Other Lipid Mediators 89 (2009), 89–97.
    • (2009) Prostaglandins & Other Lipid Mediators , vol.89 , pp. 89-97
    • Prossnitz, E.R.1    Barton, M.2
  • 239
    • 82155173499 scopus 로고    scopus 로고
    • The G-protein-coupled estrogen receptor GPER in health and disease
    • Prossnitz, E.R., Barton, M., The G-protein-coupled estrogen receptor GPER in health and disease. Nature Reviews Endocrinology 7 (2011), 715–726, 10.1038/nrendo.2011.122.
    • (2011) Nature Reviews Endocrinology , vol.7 , pp. 715-726
    • Prossnitz, E.R.1    Barton, M.2
  • 240
    • 84901491003 scopus 로고    scopus 로고
    • Estrogen biology: New insights into GPER function and clinical opportunities
    • Prossnitz, E.R., Barton, M., Estrogen biology: New insights into GPER function and clinical opportunities. Molecular and Cellular Endocrinology 389 (2014), 71–83.
    • (2014) Molecular and Cellular Endocrinology , vol.389 , pp. 71-83
    • Prossnitz, E.R.1    Barton, M.2
  • 241
    • 0036854820 scopus 로고    scopus 로고
    • Non-invasive assessment of autonomic cardiovascular control in normal human pregnancy and pregnancy- associated hypertensive disorders: A review
    • Rang, S., Wolf, H., Montfrans, G.A., Karemaker, J.M., Non-invasive assessment of autonomic cardiovascular control in normal human pregnancy and pregnancy- associated hypertensive disorders: A review. Journal of Hypertension 20 (2002), 2111–2119.
    • (2002) Journal of Hypertension , vol.20 , pp. 2111-2119
    • Rang, S.1    Wolf, H.2    Montfrans, G.A.3    Karemaker, J.M.4
  • 242
    • 0001548401 scopus 로고    scopus 로고
    • Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells
    • Razandi, M., Pedram, A., Greene, G.L., Levin, E.R., Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells. Molecular Endocrinology 13 (1999), 307–319, 10.1210/mend.13.2.0239.
    • (1999) Molecular Endocrinology , vol.13 , pp. 307-319
    • Razandi, M.1    Pedram, A.2    Greene, G.L.3    Levin, E.R.4
  • 244
    • 79953227087 scopus 로고    scopus 로고
    • The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytes
    • Recchia, A.G., De Francesco, E.M., Vivacqua, A., Sisci, D., Panno, M.L., Ando, S., Maggiolini, M., The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytes. The Journal of Biological Chemistry 286 (2011), 10773–10782, 10.1074/jbc.M110.172247.
    • (2011) The Journal of Biological Chemistry , vol.286 , pp. 10773-10782
    • Recchia, A.G.1    De Francesco, E.M.2    Vivacqua, A.3    Sisci, D.4    Panno, M.L.5    Ando, S.6    Maggiolini, M.7
  • 246
    • 84857419602 scopus 로고    scopus 로고
    • Vascular effects of estrogenic menopausal hormone therapy
    • Reslan, O.M., Khalil, R.A., Vascular effects of estrogenic menopausal hormone therapy. Reviews on Recent Clinical Trials 7 (2012), 47–70.
    • (2012) Reviews on Recent Clinical Trials , vol.7 , pp. 47-70
    • Reslan, O.M.1    Khalil, R.A.2
  • 247
    • 84880571039 scopus 로고    scopus 로고
    • Subtype-specific estrogen receptor-mediated vasodilator activity in the cephalic, thoracic, and abdominal vasculature of female rat
    • Reslan, O.M., Yin, Z., do Nascimento, G.R., Khalil, R.A., Subtype-specific estrogen receptor-mediated vasodilator activity in the cephalic, thoracic, and abdominal vasculature of female rat. Journal of Cardiovascular Pharmacology 62 (2013), 26–40, 10.1097/FJC.0b013e31828bc88a.
    • (2013) Journal of Cardiovascular Pharmacology , vol.62 , pp. 26-40
    • Reslan, O.M.1    Yin, Z.2    do Nascimento, G.R.3    Khalil, R.A.4
  • 248
    • 14844343093 scopus 로고    scopus 로고
    • A transmembrane intracellular estrogen receptor mediates rapid cell signaling
    • Revankar, C.M., Cimino, D.F., Sklar, L.A., Arterburn, J.B., Prossnitz, E.R., A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 307 (2005), 1625–1630.
    • (2005) Science , vol.307 , pp. 1625-1630
    • Revankar, C.M.1    Cimino, D.F.2    Sklar, L.A.3    Arterburn, J.B.4    Prossnitz, E.R.5
  • 250
    • 1642460897 scopus 로고
    • Oestrogen and protection against myocardial ischaemia
    • Riedel, M., Mügge, A., Oestrogen and protection against myocardial ischaemia. Lancet, 342, 1993, 872.
    • (1993) Lancet , vol.342 , pp. 872
    • Riedel, M.1    Mügge, A.2
  • 251
    • 85016257801 scopus 로고    scopus 로고
    • GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells
    • Rigiracciolo, D.C., Scarpelli, A., Lappano, R., Pisano, A., Santolla, M.F., Avino, S., De Francesco, E.M., GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells. Oncotarget 7 (2016), 94–111, 10.18632/oncotarget.6475.
    • (2016) Oncotarget , vol.7 , pp. 94-111
    • Rigiracciolo, D.C.1    Scarpelli, A.2    Lappano, R.3    Pisano, A.4    Santolla, M.F.5    Avino, S.6    De Francesco, E.M.7
  • 252
    • 0027173746 scopus 로고
    • Beneficial effect of oestrogen on exercise-induced myocardial ischaemia in women with coronary artery disease
    • Rosano, G.M., Sarrel, P.M., Poole-Wilson, P.A., Collins, P., Beneficial effect of oestrogen on exercise-induced myocardial ischaemia in women with coronary artery disease. Lancet 342 (1993), 133–136.
    • (1993) Lancet , vol.342 , pp. 133-136
    • Rosano, G.M.1    Sarrel, P.M.2    Poole-Wilson, P.A.3    Collins, P.4
  • 253
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis—An inflammatory disease
    • Ross, R., Atherosclerosis—An inflammatory disease. The New England Journal of Medicine 340 (1999), 115–126.
    • (1999) The New England Journal of Medicine , vol.340 , pp. 115-126
    • Ross, R.1
  • 254
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
    • Rossouw, J.E., Anderson, G.L., Prentice, R.L., LaCroix, A.Z., Kooperberg, C., Stefanick, M.L., Ockene, J., Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial. JAMA 288 (2002), 321–333.
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3    LaCroix, A.Z.4    Kooperberg, C.5    Stefanick, M.L.6    Ockene, J.7
  • 255
    • 22544461670 scopus 로고    scopus 로고
    • Pharmacogenomics: Harbinger for the era of personalized medicine?
    • Sadee, W., Pharmacogenomics: Harbinger for the era of personalized medicine?. Molecular Interventions 5 (2005), 140–143, 10.1124/mi.5.3.1.
    • (2005) Molecular Interventions , vol.5 , pp. 140-143
    • Sadee, W.1
  • 256
    • 77949570040 scopus 로고    scopus 로고
    • Age-associated increase in abdominal obesity and insulin resistance, and usefulness of AHA/NHLBI definition of metabolic syndrome for predicting cardiovascular disease in Japanese elderly with type 2 diabetes mellitus
    • Sakurai, T., Iimuro, S., Araki, A., Umegaki, H., Ohashi, Y., Yokono, K., Ito, H., Age-associated increase in abdominal obesity and insulin resistance, and usefulness of AHA/NHLBI definition of metabolic syndrome for predicting cardiovascular disease in Japanese elderly with type 2 diabetes mellitus. Gerontology 56 (2010), 141–149, 10.1159/000246970.
    • (2010) Gerontology , vol.56 , pp. 141-149
    • Sakurai, T.1    Iimuro, S.2    Araki, A.3    Umegaki, H.4    Ohashi, Y.5    Yokono, K.6    Ito, H.7
  • 258
    • 84871583000 scopus 로고    scopus 로고
    • G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17beta-estradiol in cancer cells and cancer-associated fibroblasts
    • Santolla, M.F., Lappano, R., De Marco, P., Pupo, M., Vivacqua, A., Sisci, D., Maggiolini, M., G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17beta-estradiol in cancer cells and cancer-associated fibroblasts. The Journal of Biological Chemistry 287 (2012), 43234–43245, 10.1074/jbc.M112.417303.
    • (2012) The Journal of Biological Chemistry , vol.287 , pp. 43234-43245
    • Santolla, M.F.1    Lappano, R.2    De Marco, P.3    Pupo, M.4    Vivacqua, A.5    Sisci, D.6    Maggiolini, M.7
  • 259
    • 78650594819 scopus 로고    scopus 로고
    • EMAS position statement: Managing the menopause in the context of coronary heart disease
    • Schenck-Gustafsson, K., Brincat, M., Erel, C.T., Gambacciani, M., Lambrinoudaki, I., Moen, M.H., EMAS, EMAS position statement: Managing the menopause in the context of coronary heart disease. Maturitas 68 (2011), 94–97, 10.1016/j.maturitas.2010.10.005.
    • (2011) Maturitas , vol.68 , pp. 94-97
    • Schenck-Gustafsson, K.1    Brincat, M.2    Erel, C.T.3    Gambacciani, M.4    Lambrinoudaki, I.5    Moen, M.H.6    EMAS7
  • 261
    • 84868307415 scopus 로고    scopus 로고
    • Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: Randomised trial
    • Schierbeck, L.L., Rejnmark, L., Tofteng, C.L., Stilgren, L., Eiken, P., Mosekilde, L., Jensen, J.E., Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: Randomised trial. BMJ, 345, 2012, e6409, 10.1136/bmj.e6409.
    • (2012) BMJ , vol.345 , pp. e6409
    • Schierbeck, L.L.1    Rejnmark, L.2    Tofteng, C.L.3    Stilgren, L.4    Eiken, P.5    Mosekilde, L.6    Jensen, J.E.7
  • 262
    • 84886546730 scopus 로고    scopus 로고
    • GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state
    • Sharma, G., Hu, C., Brigman, J.L., Zhu, G., Hathaway, H.J., Prossnitz, E.R., GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state. Endocrinology 154 (2013), 4136–4145, 10.1210/en.2013-1357.
    • (2013) Endocrinology , vol.154 , pp. 4136-4145
    • Sharma, G.1    Hu, C.2    Brigman, J.L.3    Zhu, G.4    Hathaway, H.J.5    Prossnitz, E.R.6
  • 263
    • 79960705272 scopus 로고    scopus 로고
    • Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells
    • Sharma, G., Prossnitz, E.R., Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells. Endocrinology 152 (2011), 3030–3039, 10.1210/en.2011-0091.
    • (2011) Endocrinology , vol.152 , pp. 3030-3039
    • Sharma, G.1    Prossnitz, E.R.2
  • 264
    • 34547624828 scopus 로고    scopus 로고
    • Age moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women
    • ATVBAHA.107.145383 [pii]
    • Sherwood, A., Bower, J.K., McFetridge-Durdle, J., Blumenthal, J.A., Newby, L.K., Hinderliter, A.L., Age moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women. Arteriosclerosis, Thrombosis, and Vascular Biology 27 (2007), 1782–1787, 10.1161/ATVBAHA.107.145383 ATVBAHA.107.145383 [pii].
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , pp. 1782-1787
    • Sherwood, A.1    Bower, J.K.2    McFetridge-Durdle, J.3    Blumenthal, J.A.4    Newby, L.K.5    Hinderliter, A.L.6
  • 265
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini, T., Hafezi-Moghadam, A., Brazil, D.P., Ley, K., Chin, W.W., Liao, J.K., Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407 (2000), 538–541.
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6
  • 266
    • 84964289647 scopus 로고    scopus 로고
    • A fatter, healthier but more unequal world
    • Smith, G.D., A fatter, healthier but more unequal world. Lancet 387 (2016), 1349–1350, 10.1016/S0140-6736(16)00588-2.
    • (2016) Lancet , vol.387 , pp. 1349-1350
    • Smith, G.D.1
  • 267
    • 0014665449 scopus 로고
    • Purification of estradiol receptor from rat uterus and blockade of its estrogen-binding function by specific antibody
    • Soloff, M.S., Szego, C.M., Purification of estradiol receptor from rat uterus and blockade of its estrogen-binding function by specific antibody. Biochemical and Biophysical Research Communications 34 (1969), 141–147.
    • (1969) Biochemical and Biophysical Research Communications , vol.34 , pp. 141-147
    • Soloff, M.S.1    Szego, C.M.2
  • 268
    • 0025855222 scopus 로고
    • Influence of perivascular adipose tissue on rat aortic smooth muscle responsiveness
    • Soltis, E.E., Cassis, L.A., Influence of perivascular adipose tissue on rat aortic smooth muscle responsiveness. Clinical and Experimental Hypertension. Part A 13 (1991), 277–296.
    • (1991) Clinical and Experimental Hypertension. Part A , vol.13 , pp. 277-296
    • Soltis, E.E.1    Cassis, L.A.2
  • 269
    • 0036304723 scopus 로고    scopus 로고
    • 6-Carboxymethyl genistein: A novel selective oestrogen receptor modulator (SERM) with unique, differential effects on the vasculature, bone and uterus
    • Somjen, D., Amir-Zaltsman, Y., Gayer, B., Kulik, T., Knoll, E., Stern, N., Kohen, F., 6-Carboxymethyl genistein: A novel selective oestrogen receptor modulator (SERM) with unique, differential effects on the vasculature, bone and uterus. The Journal of Endocrinology 173 (2002), 415–427.
    • (2002) The Journal of Endocrinology , vol.173 , pp. 415-427
    • Somjen, D.1    Amir-Zaltsman, Y.2    Gayer, B.3    Kulik, T.4    Knoll, E.5    Stern, N.6    Kohen, F.7
  • 271
    • 0034595287 scopus 로고    scopus 로고
    • Type II diabetes abrogates sex differences in endothelial function in premenopausal women
    • Steinberg, H.O., Paradisi, G., Cronin, J., Crowde, K., Hempfling, A., Hook, G., Baron, A.D., Type II diabetes abrogates sex differences in endothelial function in premenopausal women. Circulation 101 (2000), 2040–2046.
    • (2000) Circulation , vol.101 , pp. 2040-2046
    • Steinberg, H.O.1    Paradisi, G.2    Cronin, J.3    Crowde, K.4    Hempfling, A.5    Hook, G.6    Baron, A.D.7
  • 273
    • 73349094732 scopus 로고    scopus 로고
    • Forecasting the effects of obesity and smoking on U.S. life expectancy
    • Stewart, S.T., Cutler, D.M., Rosen, A.B., Forecasting the effects of obesity and smoking on U.S. life expectancy. New England Journal of Medicine 361 (2009), 2252–2260, 10.1056/NEJMsa0900459.
    • (2009) New England Journal of Medicine , vol.361 , pp. 2252-2260
    • Stewart, S.T.1    Cutler, D.M.2    Rosen, A.B.3
  • 274
    • 1342308238 scopus 로고    scopus 로고
    • Estrogen, inflammation and cardiovascular risk in women: A critical appraisal
    • S1043276004000062 [pii]
    • Stork, S., van der Schouw, Y.T., Grobbee, D.E., Bots, M.L., Estrogen, inflammation and cardiovascular risk in women: A critical appraisal. Trends in Endocrinology and Metabolism 15 (2004), 66–72, 10.1016/j.tem.2004.01.005 S1043276004000062 [pii].
    • (2004) Trends in Endocrinology and Metabolism , vol.15 , pp. 66-72
    • Stork, S.1    van der Schouw, Y.T.2    Grobbee, D.E.3    Bots, M.L.4
  • 275
    • 34547792318 scopus 로고    scopus 로고
    • The complex role of estrogens in inflammation
    • er.2007-0001 [pii]
    • Straub, R.H., The complex role of estrogens in inflammation. Endocrine Reviews 28 (2007), 521–574, 10.1210/er.2007-0001 er.2007-0001 [pii].
    • (2007) Endocrine Reviews , vol.28 , pp. 521-574
    • Straub, R.H.1
  • 276
    • 0030815423 scopus 로고    scopus 로고
    • Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man
    • Sudhir, K., Chou, T.M., Chatterjee, K., Smith, E.P., Williams, T.C., Kane, J.P., Rubanyi, G.M., Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. Circulation 96 (1997), 3774–3777.
    • (1997) Circulation , vol.96 , pp. 3774-3777
    • Sudhir, K.1    Chou, T.M.2    Chatterjee, K.3    Smith, E.P.4    Williams, T.C.5    Kane, J.P.6    Rubanyi, G.M.7
  • 277
    • 0030963363 scopus 로고    scopus 로고
    • Endothelial dysfunction in a man with disruptive mutation in oestrogen-receptor gene
    • Sudhir, K., Chou, T.M., Messina, L.M., Hutchison, S.J., Korach, K.S., Chatterjee, K., Rubanyi, G.M., Endothelial dysfunction in a man with disruptive mutation in oestrogen-receptor gene. Lancet 349 (1997), 1146–1147, 10.1016/S0140-6736(05)63022-X.
    • (1997) Lancet , vol.349 , pp. 1146-1147
    • Sudhir, K.1    Chou, T.M.2    Messina, L.M.3    Hutchison, S.J.4    Korach, K.S.5    Chatterjee, K.6    Rubanyi, G.M.7
  • 278
    • 0030732109 scopus 로고    scopus 로고
    • Physiological concentrations of estradiol attenuate endothelin 1-induced coronary vasoconstriction in vivo
    • Sudhir, K., Ko, E., Zellner, C., Wong, H.E., Hutchison, S.J., Chou, T.M., Chatterjee, K., Physiological concentrations of estradiol attenuate endothelin 1-induced coronary vasoconstriction in vivo. Circulation 96 (1997), 3626–3632.
    • (1997) Circulation , vol.96 , pp. 3626-3632
    • Sudhir, K.1    Ko, E.2    Zellner, C.3    Wong, H.E.4    Hutchison, S.J.5    Chou, T.M.6    Chatterjee, K.7
  • 279
    • 0031587439 scopus 로고    scopus 로고
    • Cloning of cDNAs encoding G protein-coupled receptor expressed in human endothelial cells exposed to fluid shear stress
    • Takada, Y., Kato, C., Kondo, S., Korenaga, R., Ando, J., Cloning of cDNAs encoding G protein-coupled receptor expressed in human endothelial cells exposed to fluid shear stress. Biochemical and Biophysical Research Communications 240 (1997), 737–741.
    • (1997) Biochemical and Biophysical Research Communications , vol.240 , pp. 737-741
    • Takada, Y.1    Kato, C.2    Kondo, S.3    Korenaga, R.4    Ando, J.5
  • 282
    • 84879409624 scopus 로고    scopus 로고
    • Heart failure therapy in patients with coronary artery disease
    • Taylor, C.J., Hobbs, F.D., Heart failure therapy in patients with coronary artery disease. Current Opinion in Pharmacology 13 (2013), 205–209, 10.1016/j.coph.2013.01.009.
    • (2013) Current Opinion in Pharmacology , vol.13 , pp. 205-209
    • Taylor, C.J.1    Hobbs, F.D.2
  • 283
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas, P., Pang, Y., Filardo, E.J., Dong, J., Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146 (2005), 624–632.
    • (2005) Endocrinology , vol.146 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 284
    • 79960977229 scopus 로고    scopus 로고
    • Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents beta cell failure in rodent models of type 2 diabetes
    • Tiano, J.P., Delghingaro-Augusto, V., Le May, C., Liu, S., Kaw, M.K., Khuder, S.S., Mauvais-Jarvis, F., Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents beta cell failure in rodent models of type 2 diabetes. The Journal of Clinical Investigation 121 (2011), 3331–3342, 10.1172/JCI44564.
    • (2011) The Journal of Clinical Investigation , vol.121 , pp. 3331-3342
    • Tiano, J.P.1    Delghingaro-Augusto, V.2    Le May, C.3    Liu, S.4    Kaw, M.K.5    Khuder, S.S.6    Mauvais-Jarvis, F.7
  • 285
    • 84861335162 scopus 로고    scopus 로고
    • Importance of oestrogen receptors to preserve functional beta-cell mass in diabetes
    • Tiano, J.P., Mauvais-Jarvis, F., Importance of oestrogen receptors to preserve functional beta-cell mass in diabetes. Nature Reviews Endocrinology 8 (2012), 342–351, 10.1038/nrendo.2011.242.
    • (2012) Nature Reviews Endocrinology , vol.8 , pp. 342-351
    • Tiano, J.P.1    Mauvais-Jarvis, F.2
  • 286
    • 77949496646 scopus 로고    scopus 로고
    • Coronary heart disease in postmenopausal recipients of estrogen plus progestin therapy: Does the increased risk ever disappear? A randomized trial
    • Toh, S., Hernandez-Diaz, S., Logan, R., Rossouw, J.E., Hernan, M.A., Coronary heart disease in postmenopausal recipients of estrogen plus progestin therapy: Does the increased risk ever disappear? A randomized trial. Annals of Internal Medicine 152 (2010), 211–217, 10.7326/0003-4819-152-4-201002160-00005.
    • (2010) Annals of Internal Medicine , vol.152 , pp. 211-217
    • Toh, S.1    Hernandez-Diaz, S.2    Logan, R.3    Rossouw, J.E.4    Hernan, M.A.5
  • 287
    • 84969277689 scopus 로고    scopus 로고
    • Estrogen enhances linkage in the vascular endothelial calmodulin network via a feedforward mechanism at the G protein-coupled estrogen receptor 1
    • Tran, Q.K., Firkins, R., Giles, J., Francis, S., Matnishian, V., Tran, P., Gebert-Oberle, B., Estrogen enhances linkage in the vascular endothelial calmodulin network via a feedforward mechanism at the G protein-coupled estrogen receptor 1. The Journal of Biological Chemistry, 2016, 10.1074/jbc.M115.697334.
    • (2016) The Journal of Biological Chemistry
    • Tran, Q.K.1    Firkins, R.2    Giles, J.3    Francis, S.4    Matnishian, V.5    Tran, P.6    Gebert-Oberle, B.7
  • 288
    • 34249299779 scopus 로고    scopus 로고
    • Distinct roles of estrogen receptors alpha and beta mediating acute vasodilation of epicardial coronary arteries
    • Traupe, T., Stettler, C.D., Li, H., Haas, E., Bhattacharya, I., Minotti, R., Barton, M., Distinct roles of estrogen receptors alpha and beta mediating acute vasodilation of epicardial coronary arteries. Hypertension 49 (2007), 1364–1370.
    • (2007) Hypertension , vol.49 , pp. 1364-1370
    • Traupe, T.1    Stettler, C.D.2    Li, H.3    Haas, E.4    Bhattacharya, I.5    Minotti, R.6    Barton, M.7
  • 289
    • 84950996584 scopus 로고    scopus 로고
    • Pregnancy augments G protein estrogen receptor (GPER) induced vasodilation in rat uterine arteries via the nitric oxide—cGMP signaling pathway
    • Tropea, T., De Francesco, E.M., Rigiracciolo, D., Maggiolini, M., Wareing, M., Osol, G., Mandala, M., Pregnancy augments G protein estrogen receptor (GPER) induced vasodilation in rat uterine arteries via the nitric oxide—cGMP signaling pathway. PLoS One, 10, 2015, e0141997, 10.1371/journal.pone.0141997.
    • (2015) PLoS One , vol.10 , pp. e0141997
    • Tropea, T.1    De Francesco, E.M.2    Rigiracciolo, D.3    Maggiolini, M.4    Wareing, M.5    Osol, G.6    Mandala, M.7
  • 290
    • 2542540731 scopus 로고    scopus 로고
    • Hormone therapy: Physiological complexity belies therapeutic simplicity
    • Turgeon, J.L., McDonnell, D.P., Martin, K.A., Wise, P.M., Hormone therapy: Physiological complexity belies therapeutic simplicity. Science 304 (2004), 1269–1273, 10.1126/science.1096725.
    • (2004) Science , vol.304 , pp. 1269-1273
    • Turgeon, J.L.1    McDonnell, D.P.2    Martin, K.A.3    Wise, P.M.4
  • 293
    • 31544445306 scopus 로고    scopus 로고
    • Fulvestrant, a new treatment option for advanced breast cancer: Tolerability versus existing agents
    • Vergote, I., Abram, P., Fulvestrant, a new treatment option for advanced breast cancer: Tolerability versus existing agents. Annals of Oncology 17 (2006), 200–204, 10.1093/annonc/mdj047.
    • (2006) Annals of Oncology , vol.17 , pp. 200-204
    • Vergote, I.1    Abram, P.2
  • 294
    • 34547757971 scopus 로고    scopus 로고
    • Main morbidities recorded in the women's international study of long duration oestrogen after menopause (WISDOM): A randomised controlled trial of hormone replacement therapy in postmenopausal women
    • Vickers, M.R., MacLennan, A.H., Lawton, B., Ford, D., Martin, J., Meredith, S.K., WISDOM Group, Main morbidities recorded in the women's international study of long duration oestrogen after menopause (WISDOM): A randomised controlled trial of hormone replacement therapy in postmenopausal women. BMJ, 335, 2007, 239, 10.1136/bmj.39266.425069.AD.
    • (2007) BMJ , vol.335 , pp. 239
    • Vickers, M.R.1    MacLennan, A.H.2    Lawton, B.3    Ford, D.4    Martin, J.5    Meredith, S.K.6    WISDOM Group7
  • 295
    • 59749100519 scopus 로고    scopus 로고
    • The differential effect of the phytoestrogen genistein on cardiovascular risk factors in postmenopausal women: Relationship with the metabolic status
    • Villa, P., Costantini, B., Suriano, R., Perri, C., Macri, F., Ricciardi, L., Lanzone, A., The differential effect of the phytoestrogen genistein on cardiovascular risk factors in postmenopausal women: Relationship with the metabolic status. The Journal of Clinical Endocrinology and Metabolism 94 (2009), 552–558, 10.1210/jc.2008-0735.
    • (2009) The Journal of Clinical Endocrinology and Metabolism , vol.94 , pp. 552-558
    • Villa, P.1    Costantini, B.2    Suriano, R.3    Perri, C.4    Macri, F.5    Ricciardi, L.6    Lanzone, A.7
  • 298
    • 0034674026 scopus 로고    scopus 로고
    • Mechanisms responsible for endothelial dysfunction associated with acute estrogen deprivation in normotensive women
    • Virdis, A., Ghiadoni, L., Pinto, S., Lombardo, M., Petraglia, F., Gennazzani, A., Salvetti, A., Mechanisms responsible for endothelial dysfunction associated with acute estrogen deprivation in normotensive women. Circulation 101 (2000), 2258–2263.
    • (2000) Circulation , vol.101 , pp. 2258-2263
    • Virdis, A.1    Ghiadoni, L.2    Pinto, S.3    Lombardo, M.4    Petraglia, F.5    Gennazzani, A.6    Salvetti, A.7
  • 300
    • 84859081581 scopus 로고    scopus 로고
    • Activation of GPR30 attenuates diastolic dysfunction and left ventricle remodelling in oophorectomized mRen2.Lewis rats
    • Wang, H., Jessup, J.A., Lin, M.S., Chagas, C., Lindsey, S.H., Groban, L., Activation of GPR30 attenuates diastolic dysfunction and left ventricle remodelling in oophorectomized mRen2.Lewis rats. Cardiovascular Research 94 (2012), 96–104, 10.1093/cvr/cvs090.
    • (2012) Cardiovascular Research , vol.94 , pp. 96-104
    • Wang, H.1    Jessup, J.A.2    Lin, M.S.3    Chagas, C.4    Lindsey, S.H.5    Groban, L.6
  • 301
    • 0034601671 scopus 로고    scopus 로고
    • 17beta-estradiol decreases endothelin-1 levels in the coronary circulation of postmenopausal women with coronary artery disease
    • Webb, C.M., Ghatei, M.A., McNeill, J.G., Collins, P., 17beta-estradiol decreases endothelin-1 levels in the coronary circulation of postmenopausal women with coronary artery disease. Circulation 102 (2000), 1617–1622.
    • (2000) Circulation , vol.102 , pp. 1617-1622
    • Webb, C.M.1    Ghatei, M.A.2    McNeill, J.G.3    Collins, P.4
  • 302
    • 84863982468 scopus 로고    scopus 로고
    • Nongenomic actions of aldosterone and progesterone revisited
    • Wendler, A., Albrecht, C., Wehling, M., Nongenomic actions of aldosterone and progesterone revisited. Steroids 77 (2012), 1002–1006, 10.1016/j.steroids.2011.12.023.
    • (2012) Steroids , vol.77 , pp. 1002-1006
    • Wendler, A.1    Albrecht, C.2    Wehling, M.3
  • 303
    • 0036488305 scopus 로고    scopus 로고
    • Estrogen and vascular function
    • White, R.E., Estrogen and vascular function. Vascular Pharmacology 38 (2002), 73–80.
    • (2002) Vascular Pharmacology , vol.38 , pp. 73-80
    • White, R.E.1
  • 305
    • 18844392598 scopus 로고    scopus 로고
    • Are estrogens protective or risk factors in brain injury and neurodegeneration? Reevaluation after the Women's health initiative
    • Wise, P.M., Dubal, D.B., Rau, S.W., Brown, C.M., Suzuki, S., Are estrogens protective or risk factors in brain injury and neurodegeneration? Reevaluation after the Women's health initiative. Endocrine Reviews 26 (2005), 308–312, 10.1210/er.2004-0014.
    • (2005) Endocrine Reviews , vol.26 , pp. 308-312
    • Wise, P.M.1    Dubal, D.B.2    Rau, S.W.3    Brown, C.M.4    Suzuki, S.5
  • 307
    • 0024402054 scopus 로고
    • Differential effect of nicotinic acid derivatives on smooth muscle and endothelial cell proliferation
    • Wulfroth, P., Grunwald, J., Differential effect of nicotinic acid derivatives on smooth muscle and endothelial cell proliferation. Basic Research in Cardiology 84 (1989), 291–297.
    • (1989) Basic Research in Cardiology , vol.84 , pp. 291-297
    • Wulfroth, P.1    Grunwald, J.2
  • 308
    • 84955210437 scopus 로고    scopus 로고
    • IL-4 is required for sex differences in vulnerability to focal ischemia in mice
    • Xiong, X., Xu, L., Wei, L., White, R.E., Ouyang, Y.B., Giffard, R.G., IL-4 is required for sex differences in vulnerability to focal ischemia in mice. Stroke 46 (2015), 2271–2276, 10.1161/STROKEAHA.115.008897.
    • (2015) Stroke , vol.46 , pp. 2271-2276
    • Xiong, X.1    Xu, L.2    Wei, L.3    White, R.E.4    Ouyang, Y.B.5    Giffard, R.G.6
  • 309
    • 84957111751 scopus 로고    scopus 로고
    • The effects of bazedoxifene on bone, glucose, and lipid metabolism in postmenopausal women with type 2 diabetes: An exploratory pilot study
    • Yoshii, T., Yamada, M., Minami, T., Tsunoda, T., Sasaki, M., Kondo, Y., Terauchi, Y., The effects of bazedoxifene on bone, glucose, and lipid metabolism in postmenopausal women with type 2 diabetes: An exploratory pilot study. Journal of Clinical Medicine Research 7 (2015), 762–769, 10.14740/jocmr2278w.
    • (2015) Journal of Clinical Medicine Research , vol.7 , pp. 762-769
    • Yoshii, T.1    Yamada, M.2    Minami, T.3    Tsunoda, T.4    Sasaki, M.5    Kondo, Y.6    Terauchi, Y.7
  • 310
    • 84908021916 scopus 로고    scopus 로고
    • G protein-coupled estrogen receptor 1 mediates relaxation of coronary arteries via cAMP/PKA-dependent activation of MLCP
    • Yu, X., Li, F., Klussmann, E., Stallone, J.N., Han, G., G protein-coupled estrogen receptor 1 mediates relaxation of coronary arteries via cAMP/PKA-dependent activation of MLCP. American Journal of Physiology. Endocrinology and Metabolism 307 (2014), E398–E407, 10.1152/ajpendo.00534.2013.
    • (2014) American Journal of Physiology. Endocrinology and Metabolism , vol.307 , pp. E398-E407
    • Yu, X.1    Li, F.2    Klussmann, E.3    Stallone, J.N.4    Han, G.5
  • 311
    • 80054885197 scopus 로고    scopus 로고
    • Activation of G protein-coupled estrogen receptor induces endothelium-independent relaxation of coronary artery smooth muscle
    • ajpendo.00037.2011 [pii]
    • Yu, X., Ma, H., Barman, S.A., Liu, A.T., Sellers, M., Stallone, J.N., Han, G., Activation of G protein-coupled estrogen receptor induces endothelium-independent relaxation of coronary artery smooth muscle. American Journal of Physiology. Endocrinology and Metabolism 301 (2011), E882–E888, 10.1152/ajpendo.00037.2011 ajpendo.00037.2011 [pii].
    • (2011) American Journal of Physiology. Endocrinology and Metabolism , vol.301 , pp. E882-E888
    • Yu, X.1    Ma, H.2    Barman, S.A.3    Liu, A.T.4    Sellers, M.5    Stallone, J.N.6    Han, G.7
  • 312
    • 10844258492 scopus 로고    scopus 로고
    • Selective estrogen receptor modulator idoxifene inhibits smooth muscle cell proliferation, enhances reendothelialization, and inhibits neointimal formation in vivo after vascular injury
    • Yue, T.L., Vickery-Clark, L., Louden, C.S., Gu, J.L., Ma, X.L., Narayanan, P.K., Ohlstein, E.H., Selective estrogen receptor modulator idoxifene inhibits smooth muscle cell proliferation, enhances reendothelialization, and inhibits neointimal formation in vivo after vascular injury. Circulation 102 (2000), III281–III288.
    • (2000) Circulation , vol.102 , pp. III281-III288
    • Yue, T.L.1    Vickery-Clark, L.2    Louden, C.S.3    Gu, J.L.4    Ma, X.L.5    Narayanan, P.K.6    Ohlstein, E.H.7
  • 313
    • 0036441331 scopus 로고    scopus 로고
    • The global epidemic of atherosclerotic cardiovascular disease
    • Yusuf, S., Ounpuu, S., Anand, S., The global epidemic of atherosclerotic cardiovascular disease. Medical Principles and Practice 11 (2002), 3–8.
    • (2002) Medical Principles and Practice , vol.11 , pp. 3-8
    • Yusuf, S.1    Ounpuu, S.2    Anand, S.3
  • 314
    • 84958538465 scopus 로고    scopus 로고
    • Recounting cardiac cellular composition
    • Zhou, P., Pu, W.T., Recounting cardiac cellular composition. Circulation Research 118 (2016), 368–370, 10.1161/CIRCRESAHA.116.308139.
    • (2016) Circulation Research , vol.118 , pp. 368-370
    • Zhou, P.1    Pu, W.T.2


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