Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 24, 1998, Pages 14367-14372

  Barton, Matthias ^a   Haudenschild, Christian C ^b   D'Uscio, Livius V ^a   Shaw, Sidney ^c   Münter, Klaus ^d   Lüscher, Thomas F ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b HOLLAND LABORATORY   (United States)

^c UNIVERSITY OF BERN   (Switzerland)

^d Knoll AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; APOLIPOPROTEIN E; CHOLESTEROL; DARUSENTAN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN RECEPTOR; LIPOPROTEIN; NITRIC OXIDE; NITROPRUSSIDE SODIUM; NORADRENALIN; PHENYLPROPIONIC ACID DERIVATIVE; PYRIMIDINE DERIVATIVE; TRIACYLGLYCEROL; ENDOTHELIN RECEPTOR ANTAGONIST;

ANIMAL; ARTERIOSCLEROSIS; ARTICLE; BLOOD; BLOOD PRESSURE; C57BL MOUSE; DIET; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; IN VITRO STUDY; MALE; MOUSE; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPECIES DIFFERENCE; SYSTOLE; THORACIC AORTA; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASODILATATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ATHEROMA; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL TONE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENDOTHELIUM CELL; HYPERCHOLESTEROLEMIA; LIPOPROTEIN DEFICIENCY; MEDIATOR RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; RECEPTOR BLOCKING; SMOOTH MUSCLE FIBER;

ACETYLCHOLINE; ANIMALS; AORTA, THORACIC; APOLIPOPROTEINS E; ARTERIOSCLEROSIS; BLOOD PRESSURE; CHOLESTEROL; DIET; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; HUMANS; LIPOPROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITROPRUSSIDE; NOREPINEPHRINE; PHENYLPROPIONATES; PYRIMIDINES; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN; SPECIES SPECIFICITY; SYSTOLE; TRIGLYCERIDES; VASODILATION;

EID: 0032564279     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.24.14367     Document Type: Article

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