Vasodilation by GPER in mesenteric arteries involves both endothelial nitric oxide and smooth muscle cAMP signaling

Steroids

Volumn 81, Issue , 2014, Pages 99-102

  Lindsey, Sarah H ^a   Liu, Liu ^a   Chappell, Mark C ^b  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

cAMP; Estrogen; G proteins; GPER; GPR30; Vasodilation

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 9 (TETRAHYDRO 2 FURYL)ADENINE; ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC NUCLEOTIDE; ENDOTHELIAL NITRIC OXIDE; ESTRADIOL; G PROTEIN COUPLED RECEPTOR; GUANYLATE CYCLASE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE; UNCLASSIFIED DRUG; 1-(4-(6-BROMOBENZO(1,3)DIOXOL-5-YL)-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA(C)QUINOLIN-8-YL)ETHANONE; CYCLOPENTANE DERIVATIVE; GPR30 PROTEIN, RAT; QUINOLINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL CULTURE; FEMALE; MESENTERIC ARTERY; NONHUMAN; RAT; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; VASODILATATION; AGONISTS; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; IN VITRO STUDY; LEWIS RAT; METABOLISM; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

RATTUS;

ANIMALS; CYCLIC AMP; CYCLOPENTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ESTRADIOL; FEMALE; IN VITRO TECHNIQUES; MESENTERIC ARTERIES; MUSCLE, SMOOTH, VASCULAR; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; QUINOLINES; RATS; RATS, INBRED LEW; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; VASODILATION;

EID: 84895519872     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2013.10.017     Document Type: Article

References (28)

1. S.H. Lindsey, J.A. Cohen, K.B. Brosnihan, P.E. Gallagher, and M.C. Chappell Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats Endocrinology 150 2009 3753 3758
2. S.H. Lindsey, A.S. da Silva, M.S. Silva, and M.C. Chappell Reduced vasorelaxation to estradiol and G-1 in aged female and adult male rats is associated with GPR30 downregulation Am J Physiol Endocrinol Metab 305 2013 E113 E118
3. E.J. Filardo, J.A. Quinn, A.R. Frackelton, and K.I. Bland Jr. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis Mol Endocrinol (Baltimore, Md) 16 2002 70 84
4. J. Isensee, L. Meoli, V. Zazzu, C. Nabzdyk, H. Witt, and D. Soewarto et al. Expression pattern of G protein-coupled receptor 30 in LacZ reporter mice Endocrinology 150 2009 1722 1730
5. Y. Ma, X. Qiao, A.E. Falone, O.M. Reslan, S.J. Sheppard, and R.A. Khalil Gender-specific reduction in contraction is associated with increased estrogen receptor expression in single vascular smooth muscle cells of female rat Cell Physiol Biochem 26 2010 457 470
6. B.R. Broughton, A.A. Miller, and C.G. Sobey Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries Am J Physiol Heart Circulatory Physiol 298 2010 H1055 H1061
7. S.H. Lindsey, K.A. Carver, E.R. Prossnitz, and M.C. Chappell Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat J. Cardiovasc. Pharmacol. 57 2011 598 603
8. R. Gros, Q. Ding, M. Davis, R. Shaikh, B. Liu, and J. Chorazyczewski et al. Delineating the receptor mechanisms underlying the rapid vascular contractile effects of aldosterone and estradiol Can. J. Physiol. Pharmacol. 89 2011 655 663
9. X. Yu, H. Ma, S.A. Barman, A.T. Liu, M. Sellers, and J.N. Stallone et al. Activation of G protein-coupled estrogen receptor induces endothelium- independent relaxation of coronary artery smooth muscle Am J Physiol Endocrinol Metab 301 2011 E882 E888
10. S.H. Lindsey, and E. Songu-Mize Stretch-induced TRPC4 downregulation is accompanied by reduced capacitative Ca2+ entry in WKY but not SHR mesenteric smooth muscle cells Clin. Exp. Hypertens. 32 2010 288 292
11. Z.L. Li, J.C. Liu, S.B. Liu, X.Q. Li, D.H. Yi, and M.G. Zhao Improvement of vascular function by acute and chronic treatment with the GPR30 agonist G1 in experimental diabetes mellitus PLoS One 7 2012 e38787
12. M.R. Meyer, O. Baretella, E.R. Prossnitz, and M. Barton Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780 Pharmacology 86 2010 58 64
13. J.D. Raffetto, X. Qiao, K.G. Beauregard, and R.A. Khalil Estrogen receptor-mediated enhancement of venous relaxation in female rat: implications in sex-related differences in varicose veins J. Vasc. Surg. 51 2010 972 981
14. O.M. Reslan, Z. Yin, G.R. do Nascimento, and R.A. Khalil Subtype-specific estrogen receptor-mediated vasodilator activity in the cephalic, thoracic, and abdominal vasculature of female rat J Cardiovasc Pharmacol 62 2013 26 40
15. T. Murata, H.H. Dietrich, C. Xiang, and R.G. Dacey Jr. G protein-coupled estrogen receptor agonist improves cerebral microvascular function after hypoxia/reoxygenation injury in male and female rats Stroke J Cerebral Circ 44 2013 779 785
16. S.H. Lindsey, L.M. Yamaleyeva, K.B. Brosnihan, P.E. Gallagher, and M.C. Chappell Estrogen receptor GPR30 reduces oxidative stress and proteinuria in the salt-sensitive female mRen2.Lewis rat Hypertension 58 2011 665 671
17. C.M. Szego, and J.S. Davis Adenosine 3′,5′-monophosphate in rat uterus: acute elevation by estrogen Proc Natl Acad Sci USA 58 1967 1711 1718
18. S.M. Aronica, W.L. Kraus, and B.S. Katzenellenbogen Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription Proc Natl Acad Sci USA 91 1994 8517 8521
19. J. Rodriguez, M.J. Garcia de Boto, and A. Hidalgo Mechanisms involved in the relaxant effect of estrogens on rat aorta strips Life Sci. 58 1996 607 615
20. C. Martinez, M. Sanchez, A. Hidalgo, and M.J. de Boto Mechanisms of diethylstilbestrol-induced relaxation in rat aorta smooth muscle Vascul. Pharmacol. 40 2003 197 204
21. W. Keung, P.M. Vanhoutte, and R.Y. Man Acute impairment of contractile responses by 17beta-estradiol is cAMP and protein kinase G dependent in vascular smooth muscle cells of the porcine coronary arteries Br. J. Pharmacol. 144 2005 71 79
22. 2+ by cAMP in vascular smooth muscle cells Am J Physiol Cell Physiol 258 1990 C399 C407
23. Z. Xiong, and N. Sperelakis Regulation of l-type calcium channels of vascular smooth muscle cells J. Mol. Cell. Cardiol. 27 1995 75 91
24. R.E. White, J.P. Kryman, A.M. El-Mowafy, G. Han, and G.O. Carrier CAMP-dependent vasodilators cross-activate the cGMP-dependent protein kinase to stimulate BK(Ca) channel activity in coronary artery smooth muscle cells Circ. Res. 86 2000 897 905
25. P. Komalavilas, and T.M. Lincoln Phosphorylation of the inositol 1,4,5-trisphosphate receptor by cyclic GMP-dependent protein kinase J. Biol. Chem. 269 1994 8701 8707
26. T.L. Cornwell, K.B. Pryzwansky, T.A. Wyatt, and T.M. Lincoln Regulation of sarcoplasmic reticulum protein phosphorylation by localized cyclic GMP-dependent protein kinase in vascular smooth muscle cells Mol. Pharmacol. 40 1991 923 931
27. D.R. Hathaway, M.V. Konicki, and S.A. Coolican Phosphorylation of myosin light chain kinase from vascular smooth muscle by cAMP- and cGMP-dependent protein kinases J. Mol. Cell. Cardiol. 17 1985 841 850
28. H.K. Surks, N. Mochizuki, Y. Kasai, S.P. Georgescu, K.M. Tang, and M. Ito et al. Regulation of myosin phosphatase by a specific interaction with cGMP-dependent protein kinase Iα Science (New York, NY) 286 1999 1583 1587