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Volumn 63, Issue 6, 2011, Pages 455-462

The discovery of endothelium-dependent contraction: The legacy of Paul M. Vanhoutte

Author keywords

Blood pressure; Endothelin; Endothelium; Nitric oxide; Prostanoids; Vasoactive factors; Vasoconstriction

Indexed keywords

ACETYLCHOLINE; AVOSENTAN; BOSENTAN; ENDOTHELIN 1; ENDOTHELIN 2; ENDOTHELIN 3; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; ENDOTHELIUM DERIVED CONSTRICTING FACTOR; SITAXSENTAN;

EID: 79958031263     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.02.013     Document Type: Article
Times cited : (25)

References (113)
  • 3
    • 0032718519 scopus 로고    scopus 로고
    • Endothelium-derived relaxing factor: Discovery, early studies, and identification as nitric oxide. Nobel lecture, December 8, 1998
    • Furchgott RF. Endothelium-derived relaxing factor: discovery, early studies, and identification as nitric oxide. Nobel lecture, December 8, 1998. Biosci Rep 1999;19:235-51.
    • (1999) Biosci Rep , vol.19 , pp. 235-251
    • Furchgott, R.F.1
  • 5
    • 0036134966 scopus 로고    scopus 로고
    • Endothelium and atherogenesis: Endothelial therapy revisited
    • Barton M, Haudenschild C. Endothelium and atherogenesis: endothelial therapy revisited. J Cardiovasc Pharmacol 2001;38(Suppl. 2):S23-25.
    • (2001) J Cardiovasc Pharmacol , vol.38 , Issue.SUPPL. 2
    • Barton, M.1    Haudenschild, C.2
  • 8
    • 0020336539 scopus 로고
    • Prostacyclin in physiology and pathophysiology
    • Vane JR, Bunting S, Moncada S. Prostacyclin in physiology and pathophysiology. Int Rev Exp Pathol 1982;23:161-207.
    • (1982) Int Rev Exp Pathol , vol.23 , pp. 161-207
    • Vane, J.R.1    Bunting, S.2    Moncada, S.3
  • 9
    • 0017336586 scopus 로고
    • Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachidonic acid
    • DOI 10.1016/0090-6980(77)90037-5
    • Dusting GJ, Moncada S, Vane JR. Prostacyclin (pgx) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachindonic acid. Prostaglandins 1977;13:3-15. (Pubitemid 8030252)
    • (1977) Prostaglandins , vol.13 , Issue.1 , pp. 3-15
    • Dusting, G.J.1    Moncada, S.2    Vane, J.R.3
  • 10
    • 0017094798 scopus 로고
    • An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
    • Moncada S, Gryglewski R, Bunting S, Vane JR. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 1976;263:663-5.
    • (1976) Nature , vol.263 , pp. 663-665
    • Moncada, S.1    Gryglewski, R.2    Bunting, S.3    Vane, J.R.4
  • 11
    • 0015829488 scopus 로고
    • Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis
    • Ross R, Glomset JA. Atherosclerosis and the arterial smooth muscle cell: proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis. Science 1973;180:1332-9.
    • (1973) Science , vol.180 , pp. 1332-1339
    • Ross, R.1    Glomset, J.A.2
  • 12
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • DOI 10.1038/288373a0
    • Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980;288:373-6. (Pubitemid 11169009)
    • (1980) Nature , vol.288 , Issue.5789 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 14
    • 59449098842 scopus 로고    scopus 로고
    • Endothelial function in the time of the giants
    • Heistad DD. Endothelial function in the time of the giants. J Cardiovasc Pharmacol 2008;52:385-92.
    • (2008) J Cardiovasc Pharmacol , vol.52 , pp. 385-392
    • Heistad, D.D.1
  • 15
    • 33748421398 scopus 로고    scopus 로고
    • Endothelial dysfunction: A multifaceted disorder (the Wiggers Award Lecture)
    • Feletou M, Vanhoutte PM. Endothelial dysfunction: a multifaceted disorder (the Wiggers Award Lecture). Am J Physiol Heart Circ Physiol 2006;291:H985-1002.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Feletou, M.1    Vanhoutte, P.M.2
  • 16
    • 64249116669 scopus 로고    scopus 로고
    • Prostanoids and reactive oxygen species: Team players in endothelium-dependent contractions
    • Tang EH, Vanhoutte PM. Prostanoids and reactive oxygen species: team players in endothelium-dependent contractions. Pharmacol Ther 2009;122:140-9.
    • (2009) Pharmacol Ther , vol.122 , pp. 140-149
    • Tang, E.H.1    Vanhoutte, P.M.2
  • 17
    • 56649094583 scopus 로고    scopus 로고
    • Endothelium-dependent contractions: When a good guy turns bad!
    • Vanhoutte PM, Tang EH. Endothelium-dependent contractions: when a good guy turns bad! J Physiol 2008;586:5295-304.
    • (2008) J Physiol , vol.586 , pp. 5295-5304
    • Vanhoutte, P.M.1    Tang, E.H.2
  • 18
  • 20
    • 0019996073 scopus 로고
    • Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium
    • De Mey JG, Vanhoutte PM. Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium. Circ Res 1982;51:439-47.
    • (1982) Circ Res , vol.51 , pp. 439-447
    • De Mey, J.G.1    Vanhoutte, P.M.2
  • 21
    • 0009463435 scopus 로고
    • Dilator and constrictor effects of acetylcholine on isolated rabbit aortic chains
    • Jelliffe RW. Dilator and constrictor effects of acetylcholine on isolated rabbit aortic chains. J Pharmacol Exp Ther 1962;135:349-53.
    • (1962) J Pharmacol Exp Ther , vol.135 , pp. 349-353
    • Jelliffe, R.W.1
  • 22
    • 0018427865 scopus 로고
    • Conditions which determine whether muscarinic agonists contract or relax rabbit aortic rings and strips
    • Furchgott RF, Davidson D, Lin C. Conditions which determine whether muscarinic agonists contract or relax rabbit aortic rings and strips. Blood Vessels 1979;16:213-4. (Pubitemid 9210773)
    • (1979) Blood Vessels , vol.16 , Issue.4 , pp. 213-214
    • Furchgott, R.F.1    Davidson, D.2    Lin, C.I.3
  • 23
    • 0019732146 scopus 로고
    • Role of the intima in cholinergic and purinergic relaxation of isolated canine femoral arteries
    • De Mey JG, Vanhoutte PM. Role of the intima in cholinergic and purinergic relaxation of isolated canine femoral arteries. J Physiol 1981;316:347-55.
    • (1981) J Physiol , vol.316 , pp. 347-355
    • De Mey, J.G.1    Vanhoutte, P.M.2
  • 24
  • 25
    • 73849153258 scopus 로고
    • The phosphorylase activity of the myocardium under the influence of reserpine
    • Lacroix E, Vanhoutte P, Leusen I. The phosphorylase activity of the myocardium under the influence of reserpine. Arch Int Pharmacodyn Ther 1962;138:329-33.
    • (1962) Arch Int Pharmacodyn Ther , vol.138 , pp. 329-333
    • Lacroix, E.1    Vanhoutte, P.2    Leusen, I.3
  • 26
    • 0015579589 scopus 로고
    • Venous relaxation caused by acetylcholine acting on the sympathetic nerves
    • Vanhoutte PM, Shepherd JT. Venous relaxation caused by acetylcholine acting on the sympathetic nerves. Circ Res 1973;32:259-67.
    • (1973) Circ Res , vol.32 , pp. 259-267
    • Vanhoutte, P.M.1    Shepherd, J.T.2
  • 27
    • 0016371915 scopus 로고
    • Inhibition by acetylcholine of adrenergic neurotransmission in vascular smooth muscle
    • Vanhoutte PM. Inhibition by acetylcholine of adrenergic neurotransmission in vascular smooth muscle. Circ Res 1974;34:317-26.
    • (1974) Circ Res , vol.34 , pp. 317-326
    • Vanhoutte, P.M.1
  • 28
    • 0016120850 scopus 로고
    • The action of vasodilating drugs on isolated basilar, coronary and mesenteric arteries of the dog
    • Toda N. The action of vasodilating drugs on isolated basilar, coronary and mesenteric arteries of the dog. J Pharmacol Exp Ther 1974;191:139-46.
    • (1974) J Pharmacol Exp Ther , vol.191 , pp. 139-146
    • Toda, N.1
  • 29
    • 0000137448 scopus 로고
    • The pharmacology of vascular smooth muscle
    • Furchgott RF. The pharmacology of vascular smooth muscle. Pharmacol Rev 1955;7:183-265.
    • (1955) Pharmacol Rev , vol.7 , pp. 183-265
    • Furchgott, R.F.1
  • 30
    • 0019848627 scopus 로고
    • Acetylcholine and bradykinin relax intrapulmonary arteries by acting on endothelial cells: Role in lung vascular diseases
    • Chand N, Altura BM. Acetylcholine and bradykinin relax intrapulmonary arteries by acting on endothelial cells: role in lung vascular diseases. Science 1981;213:1376-9. (Pubitemid 12243631)
    • (1981) Science , vol.213 , Issue.4514 , pp. 1376-1379
    • Chand, N.1    Altura, B.M.2
  • 31
    • 1542686292 scopus 로고
    • Hormone and neurotransmitter receptors in an established vascular endothelial cell line
    • Buonassisi V, Venter JC. Hormone and neurotransmitter receptors in an established vascular endothelial cell line. Proc Natl Acad Sci USA 1976;73:1612-6.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 1612-1616
    • Buonassisi, V.1    Venter, J.C.2
  • 32
    • 0021063422 scopus 로고
    • Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation
    • Rapoport RM, Draznin MB, Murad F. Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation. Nature 1983;306:174-6. (Pubitemid 14228339)
    • (1983) Nature , vol.306 , Issue.5939 , pp. 174-176
    • Rapoport, R.M.1    Draznin, M.B.2    Murad, F.3
  • 33
    • 0020676334 scopus 로고
    • Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP
    • Rapoport RM, Murad F. Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may bemediated through cgmp. Circ Res 1983;52:352-7. (Pubitemid 13158751)
    • (1983) Circulation Research , vol.52 , Issue.3 , pp. 352-357
    • Rapoport, R.M.1    Murad, F.2
  • 34
    • 79952272266 scopus 로고    scopus 로고
    • Genome-sequencing anniversary. The human genome at 10: Successes and challenges
    • Venter JC. Genome-sequencing anniversary. The human genome at 10: successes and challenges. Science 2011;331:546-7.
    • (2011) Science , vol.331 , pp. 546-547
    • Venter, J.C.1
  • 37
    • 0027238603 scopus 로고
    • The discovery of endothelium-dependent relaxation
    • Furchgott RF. The discovery of endothelium-dependent relaxation. Circulation 1993;87(Suppl. V):V3-8.
    • (1993) Circulation , vol.87 , Issue.SUPPL. V
    • Furchgott, R.F.1
  • 38
    • 70350051177 scopus 로고    scopus 로고
    • Furchgott, noble laureate (1916-2009) - A personal reflection
    • Martin W, Robert F. Furchgott, noble laureate (1916-2009) - a personal reflection. Br J Pharmacol 2009;158:633-7.
    • (2009) Br J Pharmacol , vol.158 , pp. 633-637
    • Martin, W.1    Robert, F.2
  • 39
    • 0021987792 scopus 로고
    • Endothelium-removal decreases relaxations of canine coronary arteries caused by beta-adrenergic agonists and adenosine
    • Rubanyi G, Vanhoutte PM. Endothelium-removal decreases relaxations of canine coronary arteries caused by beta-adrenergic agonists and adenosine. J Cardiovasc Pharmacol 1985;7:139-44. (Pubitemid 15162256)
    • (1985) Journal of Cardiovascular Pharmacology , vol.7 , Issue.1 , pp. 139-144
    • Rubanyi, G.1    Vanhoutte, P.M.2
  • 40
    • 0021022198 scopus 로고
    • 5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries
    • Cohen RA, Shepherd JT, Vanhoutte PM. 5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries. Am J Physiol 1983;245:H1077-80.
    • (1983) Am J Physiol , vol.245
    • Cohen, R.A.1    Shepherd, J.T.2    Vanhoutte, P.M.3
  • 41
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 1987;84:9265-9.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 9265-9269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 42
    • 0028332056 scopus 로고
    • Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions
    • Förstermann U, Closs EI, Pollock JS, Nakane M, Schwarz P, Gath I, et al. Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. Hypertension 1994;23:1121-31.
    • (1994) Hypertension , vol.23 , pp. 1121-1131
    • Förstermann, U.1    Closs, E.I.2    Pollock, J.S.3    Nakane, M.4    Schwarz, P.5    Gath, I.6
  • 43
    • 33645780634 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase in vascular disease: From marvel to menace
    • Forstermann U, Munzel T. Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation 2006;113:1708-14.
    • (2006) Circulation , vol.113 , pp. 1708-1714
    • Forstermann, U.1    Munzel, T.2
  • 44
    • 0012939643 scopus 로고
    • Nature of endothelium-derived relaxing factor: Are there two relaxing mediators?
    • Rubanyi GM, Vanhoutte PM. Nature of endothelium-derived relaxing factor: are there two relaxing mediators? Circ Res 1987;61:II61-7.
    • (1987) Circ Res , vol.61
    • Rubanyi, G.M.1    Vanhoutte, P.M.2
  • 45
    • 0023867044 scopus 로고
    • Endothelium-dependent hyperpolarization of canine coronary smooth muscle
    • Feletou M, Vanhoutte PM. Endothelium-dependent hyperpolarization of canine coronary smooth muscle. Br J Pharmacol 1988;93:515-24. (Pubitemid 18069063)
    • (1988) British Journal of Pharmacology , vol.93 , Issue.3 , pp. 515-524
    • Feletou, M.1    Vanhoutte, P.M.2
  • 46
    • 1542407602 scopus 로고    scopus 로고
    • Endothelium-dependent hyperpolarizations: The history
    • DOI 10.1016/j.phrs.2003.11.015, PII S1043661803004043
    • Vanhoutte PM. Endothelium-dependent hyperpolarizations: the history. Pharmacol Res 2004;49:503-8. (Pubitemid 38338659)
    • (2004) Pharmacological Research , vol.49 , Issue.6 , pp. 503-508
    • Vanhoutte, P.M.1
  • 48
    • 77952889496 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids and endothelium-dependent responses
    • Campbell WB, Fleming I. Epoxyeicosatrienoic acids and endothelium-dependent responses. Pflugers Arch 2010;459:881-95.
    • (2010) Pflugers Arch , vol.459 , pp. 881-895
    • Campbell, W.B.1    Fleming, I.2
  • 49
    • 0020647593 scopus 로고
    • Anoxia and endothelium-dependent reactivity of the canine femoral artery
    • De Mey JG, Vanhoutte PM. Anoxia and endothelium-dependent reactivity of the canine femoral artery. J Physiol 1983;335:65-74.
    • (1983) J Physiol , vol.335 , pp. 65-74
    • De Mey, J.G.1    Vanhoutte, P.M.2
  • 50
    • 0021891159 scopus 로고
    • Hypoxia releases a vasoconstrictor substance from the canine vascular endothelium
    • Rubanyi GM, Vanhoutte PM. Hypoxia releases a vasoconstrictor substance from the canine vascular endothelium. J Physiol 1985;364:45-56.
    • (1985) J Physiol , vol.364 , pp. 45-56
    • Rubanyi, G.M.1    Vanhoutte, P.M.2
  • 51
    • 0022067275 scopus 로고
    • Characterization of a coronary vasoconstrictor produced by cultured endothelial cells
    • Hickey KA, Rubanyi G, Paul RJ, Highsmith RF. Characterization of a coronary vasoconstrictor produced by cultured endothelial cells. Am J Physiol 1985;248:C550-6.
    • (1985) Am J Physiol , vol.248
    • Hickey, K.A.1    Rubanyi, G.2    Paul, R.J.3    Highsmith, R.F.4
  • 53
    • 0024047012 scopus 로고
    • Endothelium-derived contracting factor: Endothelin and/or superoxide anion?
    • Vanhoutte PM, Katusic ZS. Endothelium-derived contracting factor: endothelin and/or superoxide anion? Trends Pharmacol Sci 1988;9:229-30.
    • (1988) Trends Pharmacol Sci , vol.9 , pp. 229-230
    • Vanhoutte, P.M.1    Katusic, Z.S.2
  • 55
    • 0022456638 scopus 로고
    • Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor
    • Rubanyi GM, Vanhoutte PM. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol 1986;250:H822-827.
    • (1986) Am J Physiol , vol.250
    • Rubanyi, G.M.1    Vanhoutte, P.M.2
  • 56
    • 0024397219 scopus 로고
    • Superoxide anion is an endothelium-derived contracting factor
    • Katusic ZS, Vanhoutte PM. Superoxide anion is an endothelium-derived contracting factor. Am J Physiol 1989;257:H33-37.
    • (1989) Am J Physiol , vol.257
    • Katusic, Z.S.1    Vanhoutte, P.M.2
  • 57
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski RJ, Palmer RM, Moncada S. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 1986;320:454-6. (Pubitemid 16097810)
    • (1986) Nature , vol.320 , Issue.6061 , pp. 454-456
    • Gryglewski, R.J.1    Palmer, R.M.J.2    Moncada, S.3
  • 58
    • 0025340783 scopus 로고
    • Hypoxia increases endothelin release in bovine endothelial cells in culture, but epinephrine, norepinephrine, serotonin, histamine and angiotensin II do not
    • DOI 10.1016/0024-3205(90)90327-N
    • Hieda HS, Gomez-Sanchez CE. Hypoxia increases endothelin release in bovine endothelial cells in culture, but epinephrine, norepinephrine, serotonin, histamine and angiotensin ii do not. Life Sci 1990;47:247-51. (Pubitemid 20243805)
    • (1990) Life Sciences , vol.47 , Issue.3 , pp. 247-251
    • Hieda, H.S.1    Gomez-Sanchez, C.E.2
  • 60
    • 0027169834 scopus 로고
    • Endothelin production by hypoxic human endothelium
    • discussion 182-174
    • Gertler JP, Ocasio VH. Endothelin production by hypoxic human endothelium. J Vasc Surg 1993;18:178-82, discussion 182-174.
    • (1993) J Vasc Surg , vol.18 , pp. 178-182
    • Gertler, J.P.1    Ocasio, V.H.2
  • 62
    • 0033858177 scopus 로고    scopus 로고
    • Oxidative stress increases synthesis of big endothelin-1 by activation of the endothelin-1 promoter
    • Kahler J, Mendel S, Weckmuller J, Orzechowski HD, Mittmann C, Koster R, et al. Oxidative stress increases synthesis of big endothelin-1 by activation of the endothelin-1 promoter. J Mol Cell Cardiol 2000;32:1429-37.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 1429-1437
    • Kahler, J.1    Mendel, S.2    Weckmuller, J.3    Orzechowski, H.D.4    Mittmann, C.5    Koster, R.6
  • 64
    • 0033045445 scopus 로고    scopus 로고
    • The effect of the endothelin ET(A) receptor antagonist CI-1020 on hypoxic pulmonary vasoconstriction
    • DOI 10.1016/S0014-2999(99)00300-3, PII S0014299999003003
    • Jones RD, Wanstall JC, Gambino A, Morice AH. The effect of the endothelin ET(A) receptor antagonist ci-1020 on hypoxic pulmonary vasoconstriction. Eur J Pharmacol 1999;374:367-75. (Pubitemid 29313449)
    • (1999) European Journal of Pharmacology , vol.374 , Issue.3 , pp. 367-375
    • Jones, R.D.1    Wanstall, J.C.2    Gambino, A.3    Morice, A.H.4
  • 65
    • 0022052915 scopus 로고
    • Endothelium-dependent contractions to arachidonic acid are mediated by products of cyclooxygenase
    • Miller VM, Vanhoutte PM. Endothelium-dependent contractions to arachidonic acid are mediated by products of cyclooxygenase. Am J Physiol 1985;248:H432-7.
    • (1985) Am J Physiol , vol.248
    • Miller, V.M.1    Vanhoutte, P.M.2
  • 66
    • 0027724248 scopus 로고
    • Endothelium-dependent contractions to endothelin in the rat aorta are mediated by thromboxane A2
    • Taddei S, Vanhoutte PM. Endothelium-dependent contractions to endothelin in the rat aorta are mediated by thromboxane A2. J Cardiovasc Pharmacol 1993;22:S328-31.
    • (1993) J Cardiovasc Pharmacol , vol.22
    • Taddei, S.1    Vanhoutte, P.M.2
  • 67
    • 67651166598 scopus 로고    scopus 로고
    • COX-1 and vascular disease
    • Vanhoutte PM. COX-1 and vascular disease. Clin Pharmacol Ther 2009;86:212-5.
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 212-215
    • Vanhoutte, P.M.1
  • 68
    • 0022545417 scopus 로고
    • Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat
    • Lüscher TF, Vanhoutte PM. Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension 1986;8:344-8. (Pubitemid 16042204)
    • (1986) Hypertension , vol.8 , Issue.4 , pp. 344-348
    • Luscher, T.F.1    Vanhoutte, P.M.2
  • 69
    • 16744362572 scopus 로고    scopus 로고
    • Dysfunctional renal nitric oxide synthase as a determinant of salt-sensitive hypertension: Mechanisms of renal artery endothelial dysfunction and role of endothelin for vascular hypertrophy and glomerulosclerosis
    • Barton M, Vos I, Shaw S, Boer P, D'Uscio LV, Grone HJ, et al. Dysfunctional renal nitric oxide synthase as a determinant of salt-sensitive hypertension: mechanisms of renal artery endothelial dysfunction and role of endothelin for vascular hypertrophy and glomerulosclerosis. J Am Soc Nephrol 2000;11:835-45.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 835-845
    • Barton, M.1    Vos, I.2    Shaw, S.3    Boer, P.4    D'Uscio, L.V.5    Grone, H.J.6
  • 70
    • 0036853663 scopus 로고    scopus 로고
    • Obesity increases prostanoid-mediated vasoconstriction and vascular thromboxane receptor gene expression
    • DOI 10.1097/00004872-200211000-00024
    • Traupe T, Lang M, Goettsch W, Munter K, Morawietz H, Vetter W, et al. Obesity increases prostanoid-mediated vasoconstriction and vascular thromboxane receptor gene expression. J Hypertens 2002;20:2239-45. (Pubitemid 35388243)
    • (2002) Journal of Hypertension , vol.20 , Issue.11 , pp. 2239-2245
    • Traupe, T.1    Lang, M.2    Goettsch, W.3    Munter, K.4    Morawietz, H.5    Vetter, W.6    Barton, M.7
  • 71
    • 79953180344 scopus 로고    scopus 로고
    • Endothelium-dependent contractions in hypertension: When prostacyclin becomes ugly
    • Vanhoutte PM. Endothelium-dependent contractions in hypertension: when prostacyclin becomes ugly. Hypertension 2011;57:526-31.
    • (2011) Hypertension , vol.57 , pp. 526-531
    • Vanhoutte, P.M.1
  • 72
    • 79958056715 scopus 로고    scopus 로고
    • Endothelium-mediated control of vascular tone: Cox-1 and cox-2 products
    • Feletou M, Huang Y, Vanhoutte PM. Endothelium-mediated control of vascular tone: Cox-1 and cox-2 products. Br J Pharmacol 2011.
    • (2011) Br J Pharmacol
    • Feletou, M.1    Huang, Y.2    Vanhoutte, P.M.3
  • 73
    • 40149085142 scopus 로고    scopus 로고
    • Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension
    • DOI 10.1152/physiolgenomics.00136.2007
    • Tang EH, Vanhoutte PM. Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension. Physiol Genomics 2008;32:409-18. (Pubitemid 351328564)
    • (2008) Physiological Genomics , vol.32 , Issue.3 , pp. 409-418
    • Tang, E.H.C.1    Vanhoutte, P.M.2
  • 75
    • 0023626734 scopus 로고
    • Endothelial cells in culture produce a vasoconstrictor substance
    • DOI 10.1002/jcp.1041320210
    • O'Brien RF, Robbins RJ, McMurtry IF. Endothelial cells in culture produce a vasoconstrictor substance. J Cell Physiol 1987;132:263-70. (Pubitemid 17151479)
    • (1987) Journal of Cellular Physiology , vol.132 , Issue.2 , pp. 263-270
    • O'Brien, R.F.1    Robbins, R.J.2    McMurtry, I.F.3
  • 76
    • 79958044627 scopus 로고    scopus 로고
    • The discovery of endothelin: The power of bioassay and the role of serendipity in the discovery of endothelium-derived vasoactive substances
    • Rubanyi GM. The discovery of endothelin: the power of bioassay and the role of serendipity in the discovery of endothelium-derived vasoactive substances. Pharmacol Res 2011.
    • (2011) Pharmacol Res
    • Rubanyi, G.M.1
  • 77
    • 48849094089 scopus 로고    scopus 로고
    • Endothelin: 20 Years from discovery to therapy
    • Barton M, Yanagisawa M. Endothelin: 20 years from discovery to therapy. Can J Physiol Pharmacol 2008;86:485-98.
    • (2008) Can J Physiol Pharmacol , vol.86 , pp. 485-498
    • Barton, M.1    Yanagisawa, M.2
  • 78
    • 0025605345 scopus 로고
    • Cloning and expression of a cDNA encoding an endothelin receptor
    • Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S. Cloning and expression of a cdna encoding an endothelin receptor. Nature 1990;348:730-2. (Pubitemid 120015147)
    • (1990) Nature , vol.348 , Issue.6303 , pp. 730-732
    • Arai, H.1    Hori, S.2    Aramori, I.3    Ohkubo, H.4    Nakanishi, S.5
  • 79
    • 0025605930 scopus 로고
    • Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
    • Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kimura S, Goto K, et al. Cloning of a cdna encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 1990;348:732-5. (Pubitemid 120015148)
    • (1990) Nature , vol.348 , Issue.6303 , pp. 732-735
    • Sakurai, T.1    Yanagisawa, M.2    Takuwa, Y.3    Miyazaki, H.4    Kimura, S.5    Goto, K.6    Masaki, T.7
  • 82
    • 0032564279 scopus 로고    scopus 로고
    • Endothelin ETA receptor blockade restores no-mediated endothelial function and inhibits atherosclerosis in apoe-deficient mice
    • Barton M, Haudenschild CC, d'Uscio LV, Shaw S, Münter K, Lüscher TF. Endothelin ETA receptor blockade restores no-mediated endothelial function and inhibits atherosclerosis in apoe-deficient mice. Proc Natl Acad Sci USA 1998;95:14367-72.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14367-14372
    • Barton, M.1    Haudenschild, C.C.2    D'Uscio, L.V.3    Shaw, S.4    Münter, K.5    Lüscher, T.F.6
  • 83
    • 0032478272 scopus 로고    scopus 로고
    • Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade
    • Verhaar MC, Strachan FE, Newby DE, Cruden NL, Koomans HA, Rabelink TJ, et al. Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade. Circulation 1998;97:752-6. (Pubitemid 28135337)
    • (1998) Circulation , vol.97 , Issue.8 , pp. 752-756
    • Verhaar, M.C.1    Strachan, F.E.2    Newby, D.E.3    Cruden, N.L.4    Koomans, H.A.5    Rabelink, T.J.6    Webb, D.J.7
  • 84
    • 0033528717 scopus 로고    scopus 로고
    • Chronic endothelin receptor antagonism preserves coronary endothelial function in experimental hypercholesterolemia
    • Best PJ, McKenna CJ, Hasdai D, Holmes Jr DR, Lerman A. Chronic endothelin receptor antagonism preserves coronary endothelial function in experimental hypercholesterolemia. Circulation 1999;99:1747-52. (Pubitemid 29162489)
    • (1999) Circulation , vol.99 , Issue.13 , pp. 1747-1752
    • Best, P.J.M.1    McKenna, C.J.2    Hasdai, D.3    Holmes Jr., D.R.4    Lerman, A.5
  • 86
    • 77957289366 scopus 로고    scopus 로고
    • Long-term administration of endothelin receptor antagonist improves coronary endothelial function in patients with early atherosclerosis
    • Reriani M, Raichlin E, Prasad A, Mathew V, Pumper GM, Nelson RE, et al. Long-term administration of endothelin receptor antagonist improves coronary endothelial function in patients with early atherosclerosis. Circulation 2010;122:958-66.
    • (2010) Circulation , vol.122 , pp. 958-966
    • Reriani, M.1    Raichlin, E.2    Prasad, A.3    Mathew, V.4    Pumper, G.M.5    Nelson, R.E.6
  • 88
    • 77952542511 scopus 로고    scopus 로고
    • Deleterious combined effects of salt-loading and endothelial cell restricted endothelin-1 overexpression on blood pressure and vascular function in mice
    • Amiri F, Ko EA, Javeshghani D, Reudelhuber TL, Schiffrin EL. Deleterious combined effects of salt-loading and endothelial cell restricted endothelin-1 overexpression on blood pressure and vascular function in mice. J Hypertens 2010;28:1243-51.
    • (2010) J Hypertens , vol.28 , pp. 1243-1251
    • Amiri, F.1    Ko, E.A.2    Javeshghani, D.3    Reudelhuber, T.L.4    Schiffrin, E.L.5
  • 89
    • 43449111223 scopus 로고    scopus 로고
    • Vascular inflammation in absence of blood pressure elevation in transgenic murine model overexpressing endothelin-1 in endothelial cells
    • DOI 10.1097/HJH.0b013e3282fc2184, PII 0000487220080600000009
    • Amiri F, Paradis P, Reudelhuber TL, Schiffrin EL. Vascular inflammation in absence of blood pressure elevation in transgenic murine model overexpressing endothelin-1 in endothelial cells. J Hypertens 2008;26:1102-9. (Pubitemid 351670501)
    • (2008) Journal of Hypertension , vol.26 , Issue.6 , pp. 1102-1109
    • Amiri, F.1    Paradis, P.2    Reudelhuber, T.L.3    Schiffrin, E.L.4
  • 90
    • 5644247979 scopus 로고    scopus 로고
    • Endothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction
    • DOI 10.1161/01.CIR.0000144462.08345.B9
    • Amiri F, Virdis A, Neves MF, Iglarz M, Seidah NG, Touyz RM, et al. Endothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction. Circulation 2004;110:2233-40. (Pubitemid 39372507)
    • (2004) Circulation , vol.110 , Issue.15 , pp. 2233-2240
    • Amiri, F.1    Virdis, A.2    Fritsch, N.M.3    Iglarz, M.4    Seidah, N.G.5    Touyz, R.M.6    Reudelhuber, T.L.7    Schiffrin, E.L.8
  • 91
    • 63449101376 scopus 로고    scopus 로고
    • Endothelial endothelin-1 over-expression using receptor tyrosine kinase tie-1 promoter leads to more severe vascular permeability and blood brain barrier breakdown after transient middle cerebral artery occlusion
    • Leung JW, Chung SS, Chung SK. Endothelial endothelin-1 over-expression using receptor tyrosine kinase tie-1 promoter leads to more severe vascular permeability and blood brain barrier breakdown after transient middle cerebral artery occlusion. Brain Res 2009;1266:121-9.
    • (2009) Brain Res , vol.1266 , pp. 121-129
    • Leung, J.W.1    Chung, S.S.2    Chung, S.K.3
  • 92
    • 11144336680 scopus 로고    scopus 로고
    • Endothelial cell-specific over-expression of endothelin-1 leads to more severe cerebral damage following transient middle cerebral artery occlusion
    • Leung JW, Ho MC, Lo AC, Chung SS, Chung SK. Endothelial cell-specific over-expression of endothelin-1 leads to more severe cerebral damage following transient middle cerebral artery occlusion. J Cardiovasc Pharmacol 2004;44(Suppl1):S293-300.
    • (2004) J Cardiovasc Pharmacol , vol.44 , Issue.SUPPL. 1
    • Leung, J.W.1    Ho, M.C.2    Lo, A.C.3    Chung, S.S.4    Chung, S.K.5
  • 93
    • 72049122125 scopus 로고    scopus 로고
    • Targeted overexpression of endothelin-1 in astrocytes leads to more severe cytotoxic brain edema and higher mortality
    • Yeung PK, Lo AC, Leung JW, Chung SS, Chung SK. Targeted overexpression of endothelin-1 in astrocytes leads to more severe cytotoxic brain edema and higher mortality. J Cereb Blood Flow Metab 2009;29:1891-902.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1891-1902
    • Yeung, P.K.1    Lo, A.C.2    Leung, J.W.3    Chung, S.S.4    Chung, S.K.5
  • 94
    • 0034619523 scopus 로고    scopus 로고
    • Endothelins and endothelin receptor antagonists: Therapeutic considerations for a novel class of cardiovascular drugs
    • Luscher TF, Barton M. Endothelins and endothelin receptor antagonists: therapeutic considerations for a novel class of cardiovascular drugs. Circulation 2000;102:2434-40.
    • (2000) Circulation , vol.102 , pp. 2434-2440
    • Luscher, T.F.1    Barton, M.2
  • 95
    • 0026078601 scopus 로고
    • Endothelin receptors cloned, endothelin converting enzyme characterized and pathophysiological roles for endothelin proposed
    • Webb DJ. Endothelin receptors cloned, endothelin converting enzyme characterized and pathophysiological roles for endothelin proposed. Trends Pharmacol Sci 1991;12:43-6.
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 43-46
    • Webb, D.J.1
  • 97
    • 33744922911 scopus 로고    scopus 로고
    • Profile of past and current clinical trials involving endothelin receptor antagonists: The novel "-sentan" Class of drug
    • Maywood
    • Battistini B, Berthiaume N, Kelland NF, Webb DJ, Kohan DE. Profile of past and current clinical trials involving endothelin receptor antagonists: the novel "-sentan" Class of drug. Exp Biol Med (Maywood) 2006;231:653-95.
    • (2006) Exp Biol Med , vol.231 , pp. 653-695
    • Battistini, B.1    Berthiaume, N.2    Kelland, N.F.3    Webb, D.J.4    Kohan, D.E.5
  • 98
    • 40949132561 scopus 로고    scopus 로고
    • The endothelin system as a therapeutic target in cardiovascular disease: Great expectations or bleak house?
    • DOI 10.1038/sj.bjp.0707516, PII 0707516
    • Kirkby NS, Hadoke PW, Bagnall AJ, Webb DJ. The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house? Br J Pharmacol 2008;153:1105-19. (Pubitemid 351415492)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.6 , pp. 1105-1119
    • Kirkby, N.S.1    Hadoke, P.W.F.2    Bagnall, A.J.3    Webb, D.J.4
  • 99
    • 78149237594 scopus 로고    scopus 로고
    • Dorado: Opportunity postponed: Lessons from studies of endothelin receptor antagonists in treatment-resistant hypertension
    • Webb DJ. Dorado: opportunity postponed: lessons from studies of endothelin receptor antagonists in treatment-resistant hypertension. Hypertension 2010;56:806-7.
    • (2010) Hypertension , vol.56 , pp. 806-807
    • Webb, D.J.1
  • 100
    • 79251481135 scopus 로고    scopus 로고
    • Between confidentiality and scientific exchange: The place of publication in drug discovery and pharmaceutical research
    • Clozel M. Between confidentiality and scientific exchange: the place of publication in drug discovery and pharmaceutical research. Sci Transl Med 2011;3:67cm62.
    • (2011) Sci Transl Med , vol.3
    • Clozel, M.1
  • 104
    • 0036534412 scopus 로고    scopus 로고
    • Of mice and men: Advances in endothelin research and first antagonist gains FDA approval
    • DOI 10.1016/S0165-6147(00)01975-1, PII S0165614700019751
    • Davenport AP, Maguire JJ. Of mice and men: advances in endothelin research and first antagonist gains fda approval. Trends Pharmacol Sci 2002;23:155-7. (Pubitemid 34270588)
    • (2002) Trends in Pharmacological Sciences , vol.23 , Issue.4 , pp. 155-157
    • Davenport, A.P.1    Maguire, J.J.2
  • 106
    • 67650608427 scopus 로고    scopus 로고
    • Professor Paul M. Vanhoutte - Portrait of an extraordinary medical researcher. Interview by Iona Macdonald, MA
    • MacDonald I. Professor Paul M. Vanhoutte - portrait of an extraordinary medical researcher. Interview by Iona Macdonald, MA. Eur Heart J 2009;30:1020-2.
    • (2009) Eur Heart J , vol.30 , pp. 1020-1022
    • MacDonald, I.1
  • 108
    • 84856541603 scopus 로고    scopus 로고
    • Happy 70th birthday, Paul M. Vanhoutte
    • Duckles SP. Happy 70th birthday, Paul M. Vanhoutte. Pharmacol Int 2010;75:18. www.iuphar.org/pdf/Pharmacology-International-2010-December.pdf.
    • (2010) Pharmacol Int , vol.75 , pp. 18
    • Duckles, S.P.1
  • 109
    • 70349730265 scopus 로고    scopus 로고
    • In memoriam: Robert F. Furchgott
    • Vanhoutte PM. In memoriam: Robert F. Furchgott. J Cardiovasc Pharmacol 2009;54:179.
    • (2009) J Cardiovasc Pharmacol , vol.54 , pp. 179
    • Vanhoutte, P.M.1
  • 110
    • 0027481337 scopus 로고
    • Pharmacology. ET touches down in Houston
    • Warner TD, Vane JR. Pharmacology. ET touches down in Houston. Nature 1993;362:497-8.
    • (1993) Nature , vol.362 , pp. 497-498
    • Warner, T.D.1    Vane, J.R.2
  • 111
    • 84856531999 scopus 로고    scopus 로고
    • accessed 12.02.11
    • www.endothelin-conferences.org/Cambridge2011 [accessed 12.02.11).
  • 113
    • 46749086188 scopus 로고    scopus 로고
    • The endothelium: Thirty years of surprises
    • [article in French]. (Paris)
    • Vanhoutte PM. The endothelium: thirty years of surprises [article in French]. Ann Cardiol Angéiol (Paris) 2008;57:133-5.
    • (2008) Ann Cardiol Angéiol , vol.57 , pp. 133-135
    • Vanhoutte, P.M.1


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