메뉴 건너뛰기




Volumn 99, Issue 2, 2016, Pages 333-347

Estrogen anti-inflammatory activity on human monocytes is mediated through cross-talk between estrogen receptor ERα36 and GPR30/GPER1

Author keywords

Atherosclerosis; IL 6; Macrophages; NF kB

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ALPHA 36; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 30; G PROTEIN ESTROGEN RECEPTOR 1; INTERLEUKIN 6; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA, HUMAN; FULVESTRANT; GPER PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; ISOPROTEIN; LIPOPOLYSACCHARIDE; RELA PROTEIN, HUMAN; SMALL INTERFERING RNA;

EID: 84957612468     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.3A0914-430RR     Document Type: Article
Times cited : (140)

References (85)
  • 1
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon, S., Taylor, P. R. (2005) Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5, 953-964.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 3
    • 0036694589 scopus 로고    scopus 로고
    • IL-6 in autoimmune disease and chronic inflammatory proliferative disease
    • Ishihara, K., Hirano, T. (2002) IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev. 13, 357-368.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 357-368
    • Ishihara, K.1    Hirano, T.2
  • 4
    • 33748117796 scopus 로고    scopus 로고
    • Interleukin-6: Discovery of a pleiotropic cytokine
    • Kishimoto, T. (2006) Interleukin-6: discovery of a pleiotropic cytokine. Arthritis Res. Ther. 8(Suppl 2), S2.
    • (2006) Arthritis Res. Ther , vol.8
    • Kishimoto, T.1
  • 5
    • 0142010515 scopus 로고    scopus 로고
    • C-reactive protein and interleukin-6 in vascular disease: Culprits or passive bystanders?
    • Rattazzi, M., Puato, M., Faggin, E., Bertipaglia, B., Zambon, A., Pauletto, P. (2003) C-reactive protein and interleukin-6 in vascular disease: culprits or passive bystanders? J. Hypertens. 21, 1787-1803.
    • (2003) J. Hypertens , vol.21 , pp. 1787-1803
    • Rattazzi, M.1    Puato, M.2    Faggin, E.3    Bertipaglia, B.4    Zambon, A.5    Pauletto, P.6
  • 7
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson, G. K. (2005) Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 352, 1685-1695.
    • (2005) N. Engl. J. Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 8
    • 84938079247 scopus 로고    scopus 로고
    • Infection and atherosclerosis development
    • Campbell, L. A., Rosenfeld, M. E. (2015) Infection and atherosclerosis development. Arch. Med. Res. 46, 339-350.
    • (2015) Arch. Med. Res , vol.46 , pp. 339-350
    • Campbell, L.A.1    Rosenfeld, M.E.2
  • 9
    • 34447545492 scopus 로고    scopus 로고
    • Downregulation of migration inhibitory factor is critical for estrogen-mediated attenuation of lung tissue damage following trauma-hemorrhage
    • Hsieh, Y. C., Frink, M., Hsieh, C. H., Choudhry, M. A., Schwacha, M. G., Bland, K. I., Chaudry, I. H. (2007) Downregulation of migration inhibitory factor is critical for estrogen-mediated attenuation of lung tissue damage following trauma-hemorrhage. Am. J. Physiol. Lung Cell. Mol. Physiol. 292, L1227-L1232.
    • (2007) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.292 , pp. L1227-L1232
    • Hsieh, Y.C.1    Frink, M.2    Hsieh, C.H.3    Choudhry, M.A.4    Schwacha, M.G.5    Bland, K.I.6    Chaudry, I.H.7
  • 10
    • 0035216929 scopus 로고    scopus 로고
    • Estrogen restores cellular immunity in injured male mice via suppression of interleukin-6 production
    • Messingham, K. A., Heinrich, S. A., Kovacs, E. J. (2001) Estrogen restores cellular immunity in injured male mice via suppression of interleukin-6 production. J. Leukoc. Biol. 70, 887-895.
    • (2001) J. Leukoc. Biol , vol.70 , pp. 887-895
    • Messingham, K.A.1    Heinrich, S.A.2    Kovacs, E.J.3
  • 11
    • 38449120176 scopus 로고    scopus 로고
    • Estradiol attenuates lipopolysaccharideinduced CXC chemokine ligand 8 production by human peripheral blood monocytes
    • Pioli, P. A., Jensen, A. L., Weaver, L. K., Amiel, E., Shen, Z., Shen, L., Wira, C. R., Guyre, P. M. (2007) Estradiol attenuates lipopolysaccharideinduced CXC chemokine ligand 8 production by human peripheral blood monocytes. J. Immunol. 179, 6284-6290.
    • (2007) J. Immunol , vol.179 , pp. 6284-6290
    • Pioli, P.A.1    Jensen, A.L.2    Weaver, L.K.3    Amiel, E.4    Shen, Z.5    Shen, L.6    Wira, C.R.7    Guyre, P.M.8
  • 12
    • 38449108145 scopus 로고    scopus 로고
    • Estrogen-mediated activation of non-genomic pathway improves macrophages cytokine production following traumahemorrhage
    • Suzuki, T., Yu, H. P., Hsieh, Y. C., Choudhry, M. A., Bland, K. I., Chaudry, I. H. (2008) Estrogen-mediated activation of non-genomic pathway improves macrophages cytokine production following traumahemorrhage. J. Cell. Physiol. 214, 662-672.
    • (2008) J. Cell. Physiol , vol.214 , pp. 662-672
    • Suzuki, T.1    Yu, H.P.2    Hsieh, Y.C.3    Choudhry, M.A.4    Bland, K.I.5    Chaudry, I.H.6
  • 14
    • 0026516415 scopus 로고
    • 17 Beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: A potential mechanism for the antiosteoporotic effect of estrogens
    • Girasole, G., Jilka, R. L., Passeri, G., Boswell, S., Boder, G., Williams, D. C., Manolagas, S. C. (1992) 17 Beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens. J. Clin. Invest. 89, 883-891.
    • (1992) J. Clin. Invest , vol.89 , pp. 883-891
    • Girasole, G.1    Jilka, R.L.2    Passeri, G.3    Boswell, S.4    Boder, G.5    Williams, D.C.6    Manolagas, S.C.7
  • 16
    • 20444398494 scopus 로고    scopus 로고
    • Molecular and cellular basis of cardiovascular gender differences
    • Mendelsohn, M. E., Karas, R. H. (2005) Molecular and cellular basis of cardiovascular gender differences. Science 308, 1583-1587.
    • (2005) Science , vol.308 , pp. 1583-1587
    • Mendelsohn, M.E.1    Karas, R.H.2
  • 17
    • 0027991759 scopus 로고
    • Estrogen induces a potent suppression of experimental autoimmune encephalomyelitis and collagen-induced arthritis in mice
    • Jansson, L., Olsson, T., Holmdahl, R. (1994) Estrogen induces a potent suppression of experimental autoimmune encephalomyelitis and collagen-induced arthritis in mice. J. Neuroimmunol. 53, 203-207.
    • (1994) J. Neuroimmunol , vol.53 , pp. 203-207
    • Jansson, L.1    Olsson, T.2    Holmdahl, R.3
  • 18
    • 0022653964 scopus 로고
    • Human oestrogen receptor cDNA: Sequence, expression and homology to v-erb-A
    • Green, S., Walter, P., Kumar, V., Krust, A., Bornert, J. M., Argos, P., Chambon, P. (1986) Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature 320, 134-139.
    • (1986) Nature , vol.320 , pp. 134-139
    • Green, S.1    Walter, P.2    Kumar, V.3    Krust, A.4    Bornert, J.M.5    Argos, P.6    Chambon, P.7
  • 20
    • 84876231060 scopus 로고    scopus 로고
    • The estrogen receptor: Two or more molecules, multiple variants, diverse localizations, signaling and functions. Are we undergoing a paradigm-shift as regards their significance in breast cancer?
    • Kampa, M., Pelekanou, V., Notas, G., Stathopoulos, E. N., Castanas, E. (2013) The estrogen receptor: two or more molecules, multiple variants, diverse localizations, signaling and functions. Are we undergoing a paradigm-shift as regards their significance in breast cancer? Hormones (Athens) 12, 69-85.
    • (2013) Hormones (Athens) , vol.12 , pp. 69-85
    • Kampa, M.1    Pelekanou, V.2    Notas, G.3    Stathopoulos, E.N.4    Castanas, E.5
  • 21
    • 63849261057 scopus 로고    scopus 로고
    • G protein-coupled receptor 30: Estrogen receptor or collaborator?
    • Levin, E. R. (2009) G protein-coupled receptor 30: estrogen receptor or collaborator? Endocrinology 150, 1563-1565.
    • (2009) Endocrinology , vol.150 , pp. 1563-1565
    • Levin, E.R.1
  • 22
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas, P., Pang, Y., Filardo, E. J., Dong, J. (2005) Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146, 624-632.
    • (2005) Endocrinology , vol.146 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 23
    • 25644437706 scopus 로고    scopus 로고
    • Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66
    • Wang, Z., Zhang, X., Shen, P., Loggie, B. W., Chang, Y., Deuel, T. F. (2005) Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66. Biochem. Biophys. Res. Commun. 336, 1023-1027.
    • (2005) Biochem. Biophys. Res. Commun , vol.336 , pp. 1023-1027
    • Wang, Z.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5    Deuel, T.F.6
  • 24
    • 33745160700 scopus 로고    scopus 로고
    • A variant of estrogen receptor-alpha, hER-alpha36: Transduction of estrogen-and antiestrogen-dependent membrane-initiated mitogenic signaling
    • Wang, Z., Zhang, X., Shen, P., Loggie, B. W., Chang, Y., Deuel, T. F. (2006) A variant of estrogen receptor-alpha, hER-alpha36: transduction of estrogen-and antiestrogen-dependent membrane-initiated mitogenic signaling. Proc. Natl. Acad. Sci. USA 103, 9063-9068.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 9063-9068
    • Wang, Z.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5    Deuel, T.F.6
  • 25
    • 0034192259 scopus 로고    scopus 로고
    • Nonsteroidal anti-estrogens inhibit the functional differentiation of human monocyte-derived dendritic cells
    • Komi, J., Lassila, O. (2000) Nonsteroidal anti-estrogens inhibit the functional differentiation of human monocyte-derived dendritic cells. Blood 95, 2875-2882.
    • (2000) Blood , vol.95 , pp. 2875-2882
    • Komi, J.1    Lassila, O.2
  • 26
    • 65949089012 scopus 로고    scopus 로고
    • Estradiol regulates expression of estrogen receptor ERalpha46 in human macrophages
    • Murphy, A. J., Guyre, P. M., Wira, C. R., Pioli, P. A. (2009) Estradiol regulates expression of estrogen receptor ERalpha46 in human macrophages. PLoS One 4, e5539.
    • (2009) PLoS One , vol.4
    • Murphy, A.J.1    Guyre, P.M.2    Wira, C.R.3    Pioli, P.A.4
  • 27
    • 26844472031 scopus 로고    scopus 로고
    • Estrogen selectively promotes the differentiation of dendritic cells with characteristics of Langerhans cells
    • Mao, A., Paharkova-Vatchkova, V., Hardy, J., Miller, M. M., Kovats, S. (2005) Estrogen selectively promotes the differentiation of dendritic cells with characteristics of Langerhans cells. J. Immunol. 175, 5146-5151.
    • (2005) J. Immunol , vol.175 , pp. 5146-5151
    • Mao, A.1    Paharkova-Vatchkova, V.2    Hardy, J.3    Miller, M.M.4    Kovats, S.5
  • 29
    • 41849125275 scopus 로고    scopus 로고
    • Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue
    • Robertson, D., Savage, K., Reis-Filho, J. S., Isacke, C. M. (2008) Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue. BMC Cell Biol. 9, 13.
    • (2008) BMC Cell Biol , vol.9 , pp. 13
    • Robertson, D.1    Savage, K.2    Reis-Filho, J.S.3    Isacke, C.M.4
  • 33
    • 84863988029 scopus 로고    scopus 로고
    • Interplay of estrogen receptors and GPR30 for the regulation of early membrane initiated transcriptional effects: A pharmacological approach
    • Notas, G., Kampa, M., Pelekanou, V., Castanas, E. (2012) Interplay of estrogen receptors and GPR30 for the regulation of early membrane initiated transcriptional effects: a pharmacological approach. Steroids 77, 943-950.
    • (2012) Steroids , vol.77 , pp. 943-950
    • Notas, G.1    Kampa, M.2    Pelekanou, V.3    Castanas, E.4
  • 36
    • 0030008638 scopus 로고    scopus 로고
    • Paraffin section immunocytochemistry for estrogen receptor: The time has come
    • Taylor, C. R. (1996) Paraffin section immunocytochemistry for estrogen receptor: the time has come. Cancer 77, 2419-2422.
    • (1996) Cancer , vol.77 , pp. 2419-2422
    • Taylor, C.R.1
  • 37
    • 0029950536 scopus 로고    scopus 로고
    • Estrogen receptor immunocytochemistry in paraffin embedded tissues with ER1D5 predicts breast cancer endocrine response more accurately than H222Sp gamma in frozen sections or cytosol-based ligand-binding assays
    • Pertschuk, L. P., Feldman, J. G., Kim, Y. D., Braithwaite, L., Schneider, F., Braverman, A. S., Axiotis, C. (1996) Estrogen receptor immunocytochemistry in paraffin embedded tissues with ER1D5 predicts breast cancer endocrine response more accurately than H222Sp gamma in frozen sections or cytosol-based ligand-binding assays. Cancer 77, 2514-2519.
    • (1996) Cancer , vol.77 , pp. 2514-2519
    • Pertschuk, L.P.1    Feldman, J.G.2    Kim, Y.D.3    Braithwaite, L.4    Schneider, F.5    Braverman, A.S.6    Axiotis, C.7
  • 38
    • 84863988814 scopus 로고    scopus 로고
    • ERa36, a new variant of the ERa is expressed in triple negative breast carcinomas and has a specific transcriptomic signature in breast cancer cell lines
    • Pelekanou, V., Notas, G., Kampa, M., Tsentelierou, E., Radojicic, J., Leclercq, G., Castanas, E., Stathopoulos, E. N. (2012) ERa36, a new variant of the ERa is expressed in triple negative breast carcinomas and has a specific transcriptomic signature in breast cancer cell lines. Steroids 77, 928-934.
    • (2012) Steroids , vol.77 , pp. 928-934
    • Pelekanou, V.1    Notas, G.2    Kampa, M.3    Tsentelierou, E.4    Radojicic, J.5    Leclercq, G.6    Castanas, E.7    Stathopoulos, E.N.8
  • 41
    • 0018871095 scopus 로고
    • Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)
    • Tsuchiya, S., Yamabe, M., Yamaguchi, Y., Kobayashi, Y., Konno, T., Tada, K. (1980) Establishment and characterization of a human acute monocytic leukemia cell line (THP-1). Int. J. Cancer 26, 171-176.
    • (1980) Int. J. Cancer , vol.26 , pp. 171-176
    • Tsuchiya, S.1    Yamabe, M.2    Yamaguchi, Y.3    Kobayashi, Y.4    Konno, T.5    Tada, K.6
  • 42
    • 2642566162 scopus 로고    scopus 로고
    • 17 Beta-estradiol regulates cytokine release through modulation of CD16 expression in monocytes and monocyte-derived macrophages
    • Kramer, P. R., Kramer, S. F., Guan, G. (2004) 17 Beta-estradiol regulates cytokine release through modulation of CD16 expression in monocytes and monocyte-derived macrophages. Arthritis Rheum. 50, 1967-1975.
    • (2004) Arthritis Rheum , vol.50 , pp. 1967-1975
    • Kramer, P.R.1    Kramer, S.F.2    Guan, G.3
  • 43
    • 84857033920 scopus 로고    scopus 로고
    • The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature
    • Qin, Z. (2012) The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature. Atherosclerosis 221, 2-11.
    • (2012) Atherosclerosis , vol.221 , pp. 2-11
    • Qin, Z.1
  • 45
    • 0016606074 scopus 로고
    • Hormonal characteristics of the human menstrual cycle throughout reproductive life
    • Sherman, B. M., Korenman, S. G. (1975) Hormonal characteristics of the human menstrual cycle throughout reproductive life. J. Clin. Invest. 55, 699-706.
    • (1975) J. Clin. Invest , vol.55 , pp. 699-706
    • Sherman, B.M.1    Korenman, S.G.2
  • 46
    • 0034663421 scopus 로고    scopus 로고
    • ICI 182,780 (Faslodex): Development of a novel, "pure" antiestrogen
    • Howell, A., Osborne, C. K., Morris, C., Wakeling, A. E. (2000) ICI 182,780 (Faslodex): development of a novel, "pure" antiestrogen. Cancer 89, 817-825.
    • (2000) Cancer , vol.89 , pp. 817-825
    • Howell, A.1    Osborne, C.K.2    Morris, C.3    Wakeling, A.E.4
  • 47
    • 84859360984 scopus 로고    scopus 로고
    • GPR30, the non-classical membrane G protein related estrogen receptor, is overexpressed in human seminoma and promotes seminoma cell proliferation
    • Chevalier, N., Vega, A., Bouskine, A., Siddeek, B., Michiels, J. F., Chevallier, D., Fénichel, P. (2012) GPR30, the non-classical membrane G protein related estrogen receptor, is overexpressed in human seminoma and promotes seminoma cell proliferation. PLoS One 7, e34672.
    • (2012) PLoS One , vol.7
    • Chevalier, N.1    Vega, A.2    Bouskine, A.3    Siddeek, B.4    Michiels, J.F.5    Chevallier, D.6    Fénichel, P.7
  • 51
    • 0035927490 scopus 로고    scopus 로고
    • 17-Betaestradiol suppresses IL-2 and IL-2 receptor
    • McMurray, R. W., Ndebele, K., Hardy, K. J., Jenkins, J. K. (2001) 17-Betaestradiol suppresses IL-2 and IL-2 receptor. Cytokine 14, 324-333.
    • (2001) Cytokine , vol.14 , pp. 324-333
    • McMurray, R.W.1    Ndebele, K.2    Hardy, K.J.3    Jenkins, J.K.4
  • 52
    • 48149099758 scopus 로고    scopus 로고
    • Estrogen, NFkappaB, and the heat shock response
    • Stice, J. P., Knowlton, A. A. (2008) Estrogen, NFkappaB, and the heat shock response. Mol. Med. 14, 517-527.
    • (2008) Mol. Med , vol.14 , pp. 517-527
    • Stice, J.P.1    Knowlton, A.A.2
  • 53
    • 74849105402 scopus 로고    scopus 로고
    • Akt mediates 17betaestradiol and/or estrogen receptor-alpha inhibition of LPS-induced tumor necrosis factor-alpha expression and myocardial cell apoptosis by suppressing the JNK1/2-NFkappaB pathway
    • Liu, C. J., Lo, J. F., Kuo, C. H., Chu, C. H., Chen, L. M., Tsai, F. J., Tsai, C. H., Tzang, B. S., Kuo, W. W., Huang, C. Y. (2009) Akt mediates 17betaestradiol and/or estrogen receptor-alpha inhibition of LPS-induced tumor necrosis factor-alpha expression and myocardial cell apoptosis by suppressing the JNK1/2-NFkappaB pathway. J. Cell. Mol. Med. 13, 3655-3667.
    • (2009) J. Cell. Mol. Med , vol.13 , pp. 3655-3667
    • Liu, C.J.1    Lo, J.F.2    Kuo, C.H.3    Chu, C.H.4    Chen, L.M.5    Tsai, F.J.6    Tsai, C.H.7    Tzang, B.S.8    Kuo, W.W.9    Huang, C.Y.10
  • 54
    • 77952403219 scopus 로고    scopus 로고
    • Estradiol inhibits ongoing autoimmune neuroinflammation and NFkappaB-dependent CCL2 expression in reactive astrocytes
    • Giraud, S. N., Caron, C. M., Pham-Dinh, D., Kitabgi, P., Nicot, A. B. (2010) Estradiol inhibits ongoing autoimmune neuroinflammation and NFkappaB-dependent CCL2 expression in reactive astrocytes. Proc. Natl. Acad. Sci. USA 107, 8416-8421.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 8416-8421
    • Giraud, S.N.1    Caron, C.M.2    Pham-Dinh, D.3    Kitabgi, P.4    Nicot, A.B.5
  • 55
    • 84862517934 scopus 로고    scopus 로고
    • Estrogen modulates NFkB signaling by enhancing IkBa levels and blocking p65 binding at the promoters of inflammatory genes via estrogen receptor-b
    • Xing, D., Oparil, S., Yu, H., Gong, K., Feng, W., Black, J., Chen, Y. F., Nozell, S. (2012) Estrogen modulates NFkB signaling by enhancing IkBa levels and blocking p65 binding at the promoters of inflammatory genes via estrogen receptor-b. PLoS One 7, e36890.
    • (2012) PLoS One , vol.7
    • Xing, D.1    Oparil, S.2    Yu, H.3    Gong, K.4    Feng, W.5    Black, J.6    Chen, Y.F.7    Nozell, S.8
  • 56
    • 84875274395 scopus 로고    scopus 로고
    • Estrogen represses CXCR7 gene expression by inhibiting the recruitment of NFkB transcription factor at the CXCR7 promoter in breast cancer cells
    • Kerdivel, G., Boudot, A., Pakdel, F. (2013) Estrogen represses CXCR7 gene expression by inhibiting the recruitment of NFkB transcription factor at the CXCR7 promoter in breast cancer cells. Biochem. Biophys. Res. Commun. 431, 729-733.
    • (2013) Biochem. Biophys. Res. Commun , vol.431 , pp. 729-733
    • Kerdivel, G.1    Boudot, A.2    Pakdel, F.3
  • 58
    • 0029147741 scopus 로고
    • Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta
    • Stein, B., Yang, M. X. (1995) Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta. Mol. Cell. Biol. 15, 4971-4979.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 4971-4979
    • Stein, B.1    Yang, M.X.2
  • 59
    • 38749144353 scopus 로고    scopus 로고
    • CBP Is a dosage-dependent regulator of nuclear factorkappaB suppression by the estrogen receptor
    • Nettles, K. W., Gil, G., Nowak, J., Métivier, R., Sharma, V. B., Greene, G. L. (2008) CBP Is a dosage-dependent regulator of nuclear factorkappaB suppression by the estrogen receptor. Mol. Endocrinol. 22, 263-272.
    • (2008) Mol. Endocrinol , vol.22 , pp. 263-272
    • Nettles, K.W.1    Gil, G.2    Nowak, J.3    Métivier, R.4    Sharma, V.B.5    Greene, G.L.6
  • 63
    • 23844554880 scopus 로고    scopus 로고
    • Macrophage differentiation to foam cells
    • Shashkin, P., Dragulev, B., Ley, K. (2005) Macrophage differentiation to foam cells. Curr. Pharm. Des. 11, 3061-3072.
    • (2005) Curr. Pharm. Des , vol.11 , pp. 3061-3072
    • Shashkin, P.1    Dragulev, B.2    Ley, K.3
  • 64
    • 0035884893 scopus 로고    scopus 로고
    • 17 Beta-estradiol inhibits cytokine, chemokine, and chemokine receptor mRNA expression in the central nervous system of female mice with experimental autoimmune encephalomyelitis
    • Matejuk, A., Adlard, K., Zamora, A., Silverman, M., Vandenbark, A. A., Offner, H. (2001) 17 Beta-estradiol inhibits cytokine, chemokine, and chemokine receptor mRNA expression in the central nervous system of female mice with experimental autoimmune encephalomyelitis. J. Neurosci. Res. 65, 529-542.
    • (2001) J. Neurosci. Res , vol.65 , pp. 529-542
    • Matejuk, A.1    Adlard, K.2    Zamora, A.3    Silverman, M.4    Vandenbark, A.A.5    Offner, H.6
  • 65
    • 33750475959 scopus 로고    scopus 로고
    • Cross-talk between nuclear receptors and nuclear factor kappaB
    • De Bosscher, K., Vanden Berghe, W., Haegeman, G. (2006) Cross-talk between nuclear receptors and nuclear factor kappaB. Oncogene 25, 6868-6886.
    • (2006) Oncogene , vol.25 , pp. 6868-6886
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3
  • 66
    • 84968376891 scopus 로고    scopus 로고
    • Estrogen receptor alpha 36 gene knockdown promote the expression of NF-kB in PC12 cells
    • Zou, P., Qu, C., Xu, Y., Li, H., Han, D., Shi, D., Zou, W. (2013) Estrogen receptor alpha 36 gene knockdown promote the expression of NF-kB in PC12 cells. Open J. Endocr. Metab. Dis. 3, 20-24.
    • (2013) Open J. Endocr. Metab. Dis , vol.3 , pp. 20-24
    • Zou, P.1    Qu, C.2    Xu, Y.3    Li, H.4    Han, D.5    Shi, D.6    Zou, W.7
  • 67
    • 82155173499 scopus 로고    scopus 로고
    • The G-protein-coupled estrogen receptor GPER in health and disease
    • Prossnitz, E. R., Barton, M. (2011) The G-protein-coupled estrogen receptor GPER in health and disease. Nat. Rev. Endocrinol. 7, 715-726.
    • (2011) Nat. Rev. Endocrinol , vol.7 , pp. 715-726
    • Prossnitz, E.R.1    Barton, M.2
  • 68
    • 84931399806 scopus 로고    scopus 로고
    • International Union of Basic and Clinical Pharmacology. XCVII. G protein-coupled estrogen receptor and its pharmacologic modulators
    • Prossnitz, E. R., Arterburn, J. B. (2015) International Union of Basic and Clinical Pharmacology. XCVII. G protein-coupled estrogen receptor and its pharmacologic modulators. Pharmacol. Rev. 67, 505-540.
    • (2015) Pharmacol. Rev , vol.67 , pp. 505-540
    • Prossnitz, E.R.1    Arterburn, J.B.2
  • 70
    • 77950407928 scopus 로고    scopus 로고
    • Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling
    • Kang, L., Zhang, X., Xie, Y., Tu, Y., Wang, D., Liu, Z., Wang, Z. Y. (2010) Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling. Mol. Endocrinol. 24, 709-721.
    • (2010) Mol. Endocrinol , vol.24 , pp. 709-721
    • Kang, L.1    Zhang, X.2    Xie, Y.3    Tu, Y.4    Wang, D.5    Liu, Z.6    Wang, Z.Y.7
  • 71
    • 84862781225 scopus 로고    scopus 로고
    • 17b-Estradiol rapidly activates calcium release from intracellular stores via the GPR30 pathway and MAPK phosphorylation in osteocyte-like MLO-Y4 cells
    • Ren, J.,Wu, J. H. (2012) 17b-Estradiol rapidly activates calcium release from intracellular stores via the GPR30 pathway and MAPK phosphorylation in osteocyte-like MLO-Y4 cells. Calcif. Tissue Int. 90, 411-419.
    • (2012) Calcif. Tissue Int , vol.90 , pp. 411-419
    • Ren, J.1    Wu, J.H.2
  • 72
    • 79960908086 scopus 로고    scopus 로고
    • Differential vasoactive effects of oestrogen, oestrogen receptor agonists and selective oestrogen receptor modulators in rat middle cerebral artery
    • Patkar, S., Farr, T. D., Cooper, E., Dowell, F. J., Carswell, H. V. (2011) Differential vasoactive effects of oestrogen, oestrogen receptor agonists and selective oestrogen receptor modulators in rat middle cerebral artery. Neurosci. Res. 71, 78-84.
    • (2011) Neurosci. Res , vol.71 , pp. 78-84
    • Patkar, S.1    Farr, T.D.2    Cooper, E.3    Dowell, F.J.4    Carswell, H.V.5
  • 73
    • 84938839072 scopus 로고    scopus 로고
    • Dehydroepiandrosterone activation of G-protein-coupled estrogen receptor rapidly stimulates microRNA-21 transcription in human hepatocellular carcinoma cells
    • Teng, Y., Radde, B. N., Litchfield, L. M., Ivanova, M. M., Prough, R. A., Clark, B. J., Doll, M. A., Hein, D. W., Klinge, C. M. (2015) Dehydroepiandrosterone activation of G-protein-coupled estrogen receptor rapidly stimulates microRNA-21 transcription in human hepatocellular carcinoma cells. J. Biol. Chem. 290, 15799-15811.
    • (2015) J. Biol. Chem , vol.290 , pp. 15799-15811
    • Teng, Y.1    Radde, B.N.2    Litchfield, L.M.3    Ivanova, M.M.4    Prough, R.A.5    Clark, B.J.6    Doll, M.A.7    Hein, D.W.8    Klinge, C.M.9
  • 74
    • 84878112785 scopus 로고    scopus 로고
    • Whole transcriptome analysis of the ERa synthetic fragment P295-T311 (ERa17p) identifies specific ERaisoform (ERa, ERa36)-dependent and-independent actions in breast cancer cells
    • Notas, G., Kampa, M., Pelekanou, V., Troullinaki, M., Jacquot, Y., Leclercq, G., Castanas, E. (2013) Whole transcriptome analysis of the ERa synthetic fragment P295-T311 (ERa17p) identifies specific ERaisoform (ERa, ERa36)-dependent and-independent actions in breast cancer cells. Mol. Oncol. 7, 595-610.
    • (2013) Mol. Oncol , vol.7 , pp. 595-610
    • Notas, G.1    Kampa, M.2    Pelekanou, V.3    Troullinaki, M.4    Jacquot, Y.5    Leclercq, G.6    Castanas, E.7
  • 75
    • 0026713869 scopus 로고
    • Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors
    • Ylikomi, T., Bocquel, M. T., Berry, M., Gronemeyer, H., Chambon, P. (1992) Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors. EMBO J. 11, 3681-3694.
    • (1992) EMBO J , vol.11 , pp. 3681-3694
    • Ylikomi, T.1    Bocquel, M.T.2    Berry, M.3    Gronemeyer, H.4    Chambon, P.5
  • 77
    • 82955178219 scopus 로고    scopus 로고
    • Toll-like receptors and macrophage activation in atherosclerosis
    • Seneviratne, A. N., Sivagurunathan, B., Monaco, C. (2012) Toll-like receptors and macrophage activation in atherosclerosis. Clin. Chim. Acta 413, 3-14.
    • (2012) Clin. Chim. Acta , vol.413 , pp. 3-14
    • Seneviratne, A.N.1    Sivagurunathan, B.2    Monaco, C.3
  • 78
    • 33644755633 scopus 로고    scopus 로고
    • Interleukin-6 and diabetes: The good, the bad, or the indifferent?
    • Kristiansen, O. P., Mandrup-Poulsen, T. (2005) Interleukin-6 and diabetes: the good, the bad, or the indifferent? Diabetes 54(Suppl 2), S114-S124.
    • (2005) Diabetes , vol.54 , pp. S114-S124
    • Kristiansen, O.P.1    Mandrup-Poulsen, T.2
  • 80
    • 0035940690 scopus 로고    scopus 로고
    • NF-kappaB is required for TNF-alpha-directed smooth muscle cell migration
    • Wang, Z., Castresana, M. R., Newman, W. H. (2001) NF-kappaB is required for TNF-alpha-directed smooth muscle cell migration. FEBS Lett. 508, 360-364.
    • (2001) FEBS Lett , vol.508 , pp. 360-364
    • Wang, Z.1    Castresana, M.R.2    Newman, W.H.3
  • 81
    • 0034804397 scopus 로고    scopus 로고
    • Reactive oxygen and NF-kappaB in VEGF-induced migration of human vascular smooth muscle cells
    • Wang, Z., Castresana, M. R., Newman, W. H. (2001) Reactive oxygen and NF-kappaB in VEGF-induced migration of human vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 285, 669-674.
    • (2001) Biochem. Biophys. Res. Commun , vol.285 , pp. 669-674
    • Wang, Z.1    Castresana, M.R.2    Newman, W.H.3
  • 82
    • 84907784280 scopus 로고    scopus 로고
    • 17b-Estradiol inhibition of IL-6-Src and Cas and paxillin pathway suppresses human mesenchymal stem cells-mediated gastric cancer cell motility
    • Liu, C. J., Kuo, F. C., Hu, H. M., Chen, C. Y., Huang, Y. B., Cheng, K. H., Yokoyama, K. K., Wu, D. C., Hsieh, S., Kuo, C. H. (2014) 17b-Estradiol inhibition of IL-6-Src and Cas and paxillin pathway suppresses human mesenchymal stem cells-mediated gastric cancer cell motility. Transl. Res. 164, 232-243.
    • (2014) Transl. Res , vol.164 , pp. 232-243
    • Liu, C.J.1    Kuo, F.C.2    Hu, H.M.3    Chen, C.Y.4    Huang, Y.B.5    Cheng, K.H.6    Yokoyama, K.K.7    Wu, D.C.8    Hsieh, S.9    Kuo, C.H.10
  • 84
    • 84886005732 scopus 로고    scopus 로고
    • Estrogen signaling through the G protein-coupled estrogen receptor regulates granulocyte activation in fish
    • Cabas, I., Rodenas, M. C., Abellán, E., Meseguer, J., Mulero, V., García-Ayala, A. (2013) Estrogen signaling through the G protein-coupled estrogen receptor regulates granulocyte activation in fish. J. Immunol. 191, 4628-4639.
    • (2013) J. Immunol , vol.191 , pp. 4628-4639
    • Cabas, I.1    Rodenas, M.C.2    Abellán, E.3    Meseguer, J.4    Mulero, V.5    García-Ayala, A.6
  • 85
    • 77956300016 scopus 로고    scopus 로고
    • GPR30/GPER-1 mediates rapid decreases in TLR4 expression on murine macrophages
    • Rettew, J. A., McCall IV, S. H., Marriott, I. (2010) GPR30/GPER-1 mediates rapid decreases in TLR4 expression on murine macrophages. Mol. Cell. Endocrinol. 328, 87-92.
    • (2010) Mol. Cell. Endocrinol , vol.328 , pp. 87-92
    • Rettew, J.A.1    McCall, S.H.2    Marriott, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.