-
1
-
-
14844343093
-
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
-
DOI 10.1126/science.1106943
-
Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science. 2005;307:1625-1630. (Pubitemid 40354745)
-
(2005)
Science
, vol.307
, Issue.5715
, pp. 1625-1630
-
-
Revankar, C.M.1
Cimino, D.F.2
Sklar, L.A.3
Arterburn, J.B.4
Prossnitz, E.R.5
-
2
-
-
12344307170
-
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
-
DOI 10.1210/en.2004-1064
-
Thomas P, Pang Y, Filardo EJ, Dong J. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology. 2005;146:624-632. (Pubitemid 40129818)
-
(2005)
Endocrinology
, vol.146
, Issue.2
, pp. 624-632
-
-
Thomas, P.1
Pang, Y.2
Filardo, E.J.3
Dong, J.4
-
3
-
-
33646366423
-
Virtual and biomolecular screening converge on a selective agonist for GPR30
-
Bologa CG, Revankar CM, Young SM, Edwards BS, Arterburn JB, Kiselyov AS, Parker MA, Tkachenko SE, Savchuck NP, Sklar LA, Oprea TI, Prossnitz ER. Virtual and biomolecular screening converge on a selective agonist for GPR30. Nat Chem Biol. 2006;2:207-212.
-
(2006)
Nat Chem Biol.
, vol.2
, pp. 207-212
-
-
Bologa, C.G.1
Revankar, C.M.2
Young, S.M.3
Edwards, B.S.4
Arterburn, J.B.5
Kiselyov, A.S.6
Parker, M.A.7
Tkachenko, S.E.8
Savchuck, N.P.9
Sklar, L.A.10
Oprea, T.I.11
Prossnitz, E.R.12
-
4
-
-
67349140294
-
In vivo effects of a GPR30 antagonist
-
Dennis MK, Burai R, Ramesh C, Petrie WK, Alcon SN, Nayak TK, Bologa CG, Leitao A, Brailoiu E, Deliu E, Dun NJ, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, Prossnitz ER. In vivo effects of a GPR30 antagonist. Nat Chem Biol. 2009;5:421-427.
-
(2009)
Nat Chem Biol.
, vol.5
, pp. 421-427
-
-
Dennis, M.K.1
Burai, R.2
Ramesh, C.3
Petrie, W.K.4
Alcon, S.N.5
Nayak, T.K.6
Bologa, C.G.7
Leitao, A.8
Brailoiu, E.9
Deliu, E.10
Dun, N.J.11
Sklar, L.A.12
Hathaway, H.J.13
Arterburn, J.B.14
Oprea, T.I.15
Prossnitz, E.R.16
-
5
-
-
0141962681
-
Estrogen or the AT1 antagonist olmesartan reverses the development of profound hypertension in the congenic mRen2.Lewis rat
-
DOI 10.1161/01.HYP.0000085210.66399.A3
-
Chappell MC, Gallagher PE, Averill DB, Ferrario CM, Brosnihan KB. Estrogen or the AT1 antagonist olmesartan reverses the development of profound hypertension in the congenic mRen(2).Lewis rat. Hypertension. 2003;42:781-786. (Pubitemid 37237325)
-
(2003)
Hypertension
, vol.42
, Issue.4
, pp. 781-786
-
-
Chappell, M.C.1
Gallagher, P.E.2
Averill, D.B.3
Ferrario, C.M.4
Bridget Brosnihan, K.5
-
6
-
-
67651177687
-
Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats
-
Lindsey SH, Cohen JA, Brosnihan KB, Gallagher PE, Chappell MC. Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats. Endocrinology. 2009;150: 3753-3758.
-
(2009)
Endocrinology.
, vol.150
, pp. 3753-3758
-
-
Lindsey, S.H.1
Cohen, J.A.2
Brosnihan, K.B.3
Gallagher, P.E.4
Chappell, M.C.5
-
7
-
-
79957735539
-
Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat
-
Lindsey SH, Carver KA, Prossnitz ER, Chappell MC. Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat. J Cardiovasc Pharmacol. 2011;57:598-603.
-
(2011)
J Cardiovasc Pharmacol.
, vol.57
, pp. 598-603
-
-
Lindsey, S.H.1
Carver, K.A.2
Prossnitz, E.R.3
Chappell, M.C.4
-
9
-
-
77953823128
-
Influence of estrogen depletion and salt loading on renal angiotensinogen expression in the mRen(2).Lewis strain
-
Cohen JA, Lindsey SH, Pirro NT, Brosnihan KB, Gallagher PE, Chappell MC. Influence of estrogen depletion and salt loading on renal angiotensinogen expression in the mRen(2).Lewis strain. Am J Physiol Renal Physiol. 2010;299:F35-F42.
-
(2010)
Am J Physiol Renal Physiol.
, vol.299
-
-
Cohen, J.A.1
Lindsey, S.H.2
Pirro, N.T.3
Brosnihan, K.B.4
Gallagher, P.E.5
Chappell, M.C.6
-
10
-
-
80053502978
-
Antifibrotic effects of the nNOS inhibitor L-VNIO are associated with reduced oxidative stress in the kidney
-
Yamaleyeva LM, Chappell MC. Antifibrotic effects of the nNOS inhibitor L-VNIO are associated with reduced oxidative stress in the kidney. Hypertension. 2008;52:e116.
-
(2008)
Hypertension.
, vol.52
-
-
Yamaleyeva, L.M.1
Chappell, M.C.2
-
11
-
-
78149487334
-
Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats
-
Jessup JA, Lindsey SH, Wang H, Chappell MC, Groban L. Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats. PLoS One. 2010;5:e15433.
-
(2010)
PLoS One.
, vol.5
-
-
Jessup, J.A.1
Lindsey, S.H.2
Wang, H.3
Chappell, M.C.4
Groban, L.5
-
12
-
-
53249107839
-
G proteincoupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol
-
Otto C, Rohde-Schulz B, Schwarz G, Fuchs I, Klewer M, Brittain D, Langer G, Bader B, Prelle K, Nubbemeyer R, Fritzemeier KH. G proteincoupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol. Endocrinology. 2008;149:4846-4856.
-
(2008)
Endocrinology.
, vol.149
, pp. 4846-4856
-
-
Otto, C.1
Rohde-Schulz, B.2
Schwarz, G.3
Fuchs, I.4
Klewer, M.5
Brittain, D.6
Langer, G.7
Bader, B.8
Prelle, K.9
Nubbemeyer, R.10
Fritzemeier, K.H.11
-
13
-
-
77950407928
-
Involvement of estrogen receptor variant ER-α36, not GPR30, in nongenomic estrogen signaling
-
Kang L, Zhang X, Xie Y, Tu Y, Wang D, Liu Z, Wang ZY. Involvement of estrogen receptor variant ER-α36, not GPR30, in nongenomic estrogen signaling. Mol Endocrinol. 2010;24:709-721.
-
(2010)
Mol Endocrinol.
, vol.24
, pp. 709-721
-
-
Kang, L.1
Zhang, X.2
Xie, Y.3
Tu, Y.4
Wang, D.5
Liu, Z.6
Wang, Z.Y.7
-
14
-
-
25644437706
-
Identification, cloning, and expression of human estrogen receptor-α36, a novel variant of human estrogen receptor-α66
-
DOI 10.1016/j.bbrc.2005.08.226, PII S0006291X05019510
-
Wang Z, Zhang X, Shen P, Loggie BW, Chang Y, Deuel TF. Identification, cloning, and expression of human estrogen receptor-α36, a novel variant of human estrogen receptor-α66. Biochem Biophys Res Commun. 2005;336:1023-1027. (Pubitemid 41383424)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.336
, Issue.4
, pp. 1023-1027
-
-
Zhao, Y.W.1
Zhang, X.2
Shen, P.3
Loggie, B.W.4
Chang, Y.5
Deuel, T.F.6
-
15
-
-
0032857025
-
Megalin knockout mice as an animal model of low molecular weight proteinuria
-
Leheste JR, Rolinski B, Vorum H, Hilpert J, Nykjaer A, Jacobsen C, Aucouturier P, Moskaug JO, Otto A, Christensen EI, Willnow TE. Megalin knockout mice as an animal model of low molecular weight proteinuria. Am J Pathol. 1999;155:1361-1370. (Pubitemid 29488943)
-
(1999)
American Journal of Pathology
, vol.155
, Issue.4
, pp. 1361-1370
-
-
Leheste, J.-R.1
Rolinski, B.2
Vorum, H.3
Hilpert, J.4
Nykjaer, A.5
Jacobsen, C.6
Aucouturier, P.7
Moskaug, J.O.8
Otto, A.9
Christensen, E.I.10
Willnow, T.E.11
-
16
-
-
70349248419
-
Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues
-
Hazell GG, Yao ST, Roper JA, Prossnitz ER, O'Carroll AM, Lolait SJ. Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues. J Endocrinol. 2009;202:223-236.
-
(2009)
J Endocrinol.
, vol.202
, pp. 223-236
-
-
Hazell, G.G.1
Yao, S.T.2
Roper, J.A.3
Prossnitz, E.R.4
O'Carroll, A.M.5
Lolait, S.J.6
-
17
-
-
77957287391
-
Profiling oestrogens and testosterone in human urine by stable isotope dilution/benchtop gas chromatography-mass spectrometry
-
Hoffmann P, Hartmann MF, Remer T, Zimmer KP, Wudy SA. Profiling oestrogens and testosterone in human urine by stable isotope dilution/benchtop gas chromatography-mass spectrometry. Steroids. 2010;75: 1067-1074.
-
(2010)
Steroids.
, vol.75
, pp. 1067-1074
-
-
Hoffmann, P.1
Hartmann, M.F.2
Remer, T.3
Zimmer, K.P.4
Wudy, S.A.5
-
18
-
-
0031028511
-
Gonadal hormones modulate deoxycorticosterone-salt hypertension in male and female rats
-
Crofton JT, Share L. Gonadal hormones modulate deoxycorticosterone-salt hypertension in male and female rats. Hypertension. 1997;29:494-499. (Pubitemid 27074089)
-
(1997)
Hypertension
, vol.29
, Issue.1
, pp. 494-499
-
-
Crofton, J.T.1
Share, L.2
-
19
-
-
0348109423
-
Postovariectomy hypertension is linked to increased renal AT1 receptor and salt sensitivity
-
DOI 10.1161/01.HYP.0000102180.13341.50
-
Harrison-Bernard LM, Schulman IH, Raij L. Postovariectomy hypertension is linked to increased renal AT1 receptor and salt sensitivity. Hypertension. 2003;42:1157-1163. (Pubitemid 37549071)
-
(2003)
Hypertension
, vol.42
, Issue.6
, pp. 1157-1163
-
-
Harrison-Bernard, L.M.1
Schulman, I.H.2
Raij, L.3
-
20
-
-
34748862634
-
Expression of G protein-coupled receptor 30 in the hamster ovary: Differential regulation by gonadotropins and steroid hormones
-
DOI 10.1210/en.2007-0727
-
Wang C, Prossnitz ER, Roy SK. Expression of G protein-coupled receptor 30 in the hamster ovary: differential regulation by gonadotropins and steroid hormones. Endocrinology. 2007;148:4853-4864. (Pubitemid 47481550)
-
(2007)
Endocrinology
, vol.148
, Issue.10
, pp. 4853-4864
-
-
Wang, C.1
Prossnitz, E.R.2
Roy, S.K.3
-
21
-
-
0036724050
-
Superoxide dismutase and oxidative stress in Dahl salt-sensitive and -resistant rats
-
Meng S, Roberts LJ, Cason GW, Curry TS, Manning RD Jr. Superoxide dismutase and oxidative stress in Dahl salt-sensitive and-resistant rats. Am J Physiol Regul Integr Comp Physiol. 2002;283:R732-R738. (Pubitemid 34951626)
-
(2002)
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
, vol.283
-
-
Meng, S.1
Jackson Roberts II, L.2
Cason, G.W.3
Curry, T.S.4
Davis Manning Jr., R.5
-
22
-
-
34250314383
-
Female protection in progressive renal disease is associated with estradiol attenuation of superoxide production
-
DOI 10.1016/S1550-8579(07)80009-X, PII S155085790780009X
-
Ji H, Zheng W, Menini S, Pesce C, Kim J, Wu X, Mulroney SE, Sandberg K. Female protection in progressive renal disease is associated with estradiol attenuation of superoxide production. Gend Med. 2007;4:56-71. (Pubitemid 46917068)
-
(2007)
Gender Medicine
, vol.4
, Issue.1
, pp. 56-71
-
-
Ji, H.1
Zheng, W.2
Menini, S.3
Pesce, C.4
Kim, J.5
Wu, X.6
Mulroney, S.E.7
Sandberg, K.8
-
23
-
-
34250357149
-
Differential regulation of thioredoxin and NAD(P)H oxidase by angiotensin II in male and female mice
-
DOI 10.1097/HJH.0b013e3280acac60, PII 0000487220070600000014
-
Ebrahimian T, He Y, Schiffrin EL, Touyz RM. Differential regulation of thioredoxin and NAD(P)H oxidase by angiotensin II in male and female mice. J Hypertens. 2007;25:1263-1271. (Pubitemid 46918806)
-
(2007)
Journal of Hypertension
, vol.25
, Issue.6
, pp. 1263-1271
-
-
Ebrahimian, T.1
He, Y.2
Schiffrin, E.L.3
Touyz, R.M.4
-
24
-
-
9444255256
-
Estradiol regulates the thioredoxin antioxidant system in the mouse uterus
-
DOI 10.1210/en.2004-0471
-
Deroo BJ, Hewitt SC, Peddada SD, Korach KS. Estradiol regulates the thioredoxin antioxidant system in the mouse uterus. Endocrinology. 2004; 145:5485-5492. (Pubitemid 39564588)
-
(2004)
Endocrinology
, vol.145
, Issue.12
, pp. 5485-5492
-
-
Deroo, B.J.1
Hewitt, S.C.2
Peddada, S.D.3
Korach, K.S.4
-
25
-
-
23844445847
-
[MAPK]/NFκB cascade
-
DOI 10.1111/j.1474-9726.2005.00151.x
-
Borras C, Gambini J, Gomez-Cabrera MC, Sastre J, Pallardo FV, Mann GE, Vina J. 17β-Oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NFkappaB cascade. Aging Cell. 2005;4:113-118. (Pubitemid 41602744)
-
(2005)
Aging Cell
, vol.4
, Issue.3
, pp. 113-118
-
-
Borras, C.1
Gambini, J.2
Gomez-Cabrera, Ma.C.3
Sastre, J.4
Pallardo, F.V.5
Mann, G.E.6
Vina, J.7
-
26
-
-
77749242708
-
Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries
-
Broughton BR, Miller AA, Sobey CG. Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries. Am J Physiol Heart Circ Physiol. 2010;298:H1055-H1061.
-
(2010)
Am J Physiol Heart Circ Physiol.
, vol.298
-
-
Broughton, B.R.1
Miller, A.A.2
Sobey, C.G.3
-
27
-
-
33846886531
-
Proximal tubule microvilli remodeling and albuminuria in the Ren2 transgenic rat
-
DOI 10.1152/ajprenal.00252.2006
-
Hayden MR, Chowdhury NA, Cooper SA, Whaley-Connell A, Habibi J, Witte L, Wiedmeyer C, Manrique CM, Lastra G, Ferrario C, Stump C, Sowers JR. Proximal tubule microvilli remodeling and albuminuria in the Ren2 transgenic rat. Am J Physiol Renal Physiol. 2007;292:F861-F867. (Pubitemid 46220556)
-
(2007)
American Journal of Physiology - Renal Physiology
, vol.292
, Issue.2
-
-
Hayden, M.R.1
Chowdhury, N.A.2
Cooper, S.A.3
Whaley-Connell, A.4
Habibi, J.5
Witte, L.6
Wiedmeyer, C.7
Manrique, C.M.8
Lastra, G.9
Ferrario, C.10
Stump, C.11
Sowers, J.R.12
-
28
-
-
84984766757
-
Megalin and cubilin: Multifunctional endocytic receptors
-
DOI 10.1038/nrm750
-
Christensen EI, Birn H. Megalin and cubilin: multifunctional endocytic receptors. Nat Rev Mol Cell Biol. 2002;3:256-266. (Pubitemid 34619261)
-
(2002)
Nature Reviews Molecular Cell Biology
, vol.3
, Issue.4
, pp. 256-266
-
-
Christensen, E.I.1
Birn, H.2
-
29
-
-
0034805307
-
Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats
-
Tojo A, Onozato ML, Ha H, Kurihara H, Sakai T, Goto A, Fujita T, Endou H. Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats. Histochem Cell Biol. 2001;116:269-276. (Pubitemid 32930140)
-
(2001)
Histochemistry and Cell Biology
, vol.116
, Issue.3
, pp. 269-276
-
-
Tojo, A.1
Onozato, M.2
Ha, H.3
Kurihara, H.4
Sakai, T.5
Goto, A.6
Fujita, T.7
Endou, H.8
-
30
-
-
33845505232
-
PKB and megalin determine the survival or death of renal proximal tubule cells
-
DOI 10.1073/pnas.0605029103
-
Caruso-Neves C, Pinheiro AA, Cai H, Souza-Menezes J, Guggino WB. PKB and megalin determine the survival or death of renal proximal tubule cells. Proc Natl Acad Sci USA. 2006;103:18810-18815. (Pubitemid 44913492)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.49
, pp. 18810-18815
-
-
Caruso-Meves, C.1
Pinheiro, A.A.S.2
Cai, H.3
Souza-Menezes, J.4
Guggino, W.B.5
-
31
-
-
0033968875
-
Receptor-associated protein is important for normal processing of megalin in kidney proximal tubules
-
Birn H, Vorum H, Verroust PJ, Moestrup SK, Christensen EI. Receptorassociated protein is important for normal processing of megalin in kidney proximal tubules. J Am Soc Nephrol. 2000;11:191-202. (Pubitemid 30064842)
-
(2000)
Journal of the American Society of Nephrology
, vol.11
, Issue.2
, pp. 191-202
-
-
Birn, H.1
Vorum, H.2
Verroust, P.J.3
Moestrup, S.K.4
Christensen, E.I.5
-
32
-
-
0034880576
-
Role of megalin in renal handling of aminoglycosides
-
Nagai J, Tanaka H, Nakanishi N, Murakami T, Takano M. Role of megalin in renal handling of aminoglycosides. Am J Physiol Renal Physiol. 2001;281:F337-F344.
-
(2001)
Am J Physiol Renal Physiol.
, vol.281
-
-
Nagai, J.1
Tanaka, H.2
Nakanishi, N.3
Murakami, T.4
Takano, M.5
-
33
-
-
4544339737
-
Linking receptor-mediated endocytosis and cell signaling: Evidence for regulated intramembrane proteolysis of megalin in proximal tubule
-
DOI 10.1074/jbc.M405608200
-
Zou Z, Chung B, Nguyen T, Mentone S, Thomson B, Biemesderfer D. Linking receptor-mediated endocytosis and cell signaling: evidence for regulated intramembrane proteolysis of megalin in proximal tubule. J Biol Chem. 2004;279:34302-34310. (Pubitemid 39318054)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34302-34310
-
-
Zou, Z.1
Chung, B.2
Nguyen, T.3
Mentone, S.4
Thomson, B.5
Biemesderfer, D.6
-
34
-
-
0035072345
-
Different associations of blood pressure with 24-hour urinary sodium excretion among pre- and post-menopausal women
-
DOI 10.1097/00004872-200103001-00003
-
Yamori Y, Liu L, Ikeda K, Mizushima S, Nara Y, Simpson FO. Different associations of blood pressure with 24-hour urinary sodium excretion among pre-and post-menopausal women: WHO Cardiovascular Diseases and Alimentary Comparison (WHO-CARDIAC) Study. J Hypertens. 2001;19:535-538. (Pubitemid 32280944)
-
(2001)
Journal of Hypertension
, vol.19
, Issue.3 SUPPL.
, pp. 535-538
-
-
Yamori, Y.1
Liu, L.2
Ikeda, K.3
Mizushima, S.4
Nara, Y.5
Simpson, F.O.6
-
35
-
-
33744974062
-
Surgical menopause increases salt sensitivity of blood pressure
-
DOI 10.1161/01.HYP.0000218857.67880.75, PII 0000426820060600000023
-
Schulman IH, Aranda P, Raij L, Veronesi M, Aranda FJ, Martin R. Surgical menopause increases salt sensitivity of blood pressure. Hypertension. 2006;47:1168-1174. (Pubitemid 44289175)
-
(2006)
Hypertension
, vol.47
, Issue.6
, pp. 1168-1174
-
-
Schulman, I.H.1
Aranda, P.2
Raij, L.3
Veronesi, M.4
Aranda, F.J.5
Martin, R.6
|