GPER activation ameliorates aortic remodeling induced by salt-sensitive hypertension

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 310, Issue 8, 2016, Pages H953-H961

  Liu, Liu ^a   Kashyap, Shreya ^a   Murphy, Brennah ^a   Hutson, Dillion D ^a   Budish, Rebecca A ^a   Trimmer, Emma H ^a   Zimmerman, Margaret A ^a   Trask, Aaron J ^b   Miller, Kristin S ^c   Chappell, Mark C ^d   Lindsey, Sarah H ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONWIDE CHILDREN S HOSPITAL   (United States)

^c TULANE UNIVERSITY   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Estrogen; Glycosaminoglycans; Oxidative stress; Salt sensitive hypertension; Vascular remodeling

Indexed keywords

ANGIOTENSIN II; ANTIOXIDANT; COLLAGEN; COPPER ZINC SUPEROXIDE DISMUTASE; ELASTIN; ESTROGEN RECEPTOR; G 1; G PROTEIN COUPLED ESTROGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLYCOSAMINOGLYCAN; LIPID PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; NEURONAL NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; PROTECTIVE AGENT; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE; STEROID HORMONE RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; 1-(4-(6-BROMOBENZO(1,3)DIOXOL-5-YL)-3A,4,5,9B-TETRAHYDRO-3H-CYCLOPENTA(C)QUINOLIN-8-YL)ETHANONE; CYCLOPENTANE DERIVATIVE; GPR30 PROTEIN, RAT; QUINOLINE DERIVATIVE; RENIN; SALT INTAKE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA DISEASE; AORTIC REMODELING; ARTERIAL WALL THICKENING; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD VESSEL INJURY; BLOOD VESSEL PARAMETERS; BLOOD VESSEL REACTIVITY; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ELEVATED BLOOD PRESSURE; EX VIVO STUDY; FEMALE; HYPERTENSION; LIPID PEROXIDATION; MEDIA TO LUMEN RATIO; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SALT INTAKE; SALT LOADING; SALT SENSITIVE HYPERTENSION; SYSTOLIC BLOOD PRESSURE; VASCULAR REMODELING; AGONISTS; ANIMAL; AORTA; BLOOD PRESSURE; CONGENIC STRAIN; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; GENETICS; GENOTYPE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; TIME FACTOR; TRANSGENIC RAT;

ANGIOTENSIN II; ANIMALS; ANIMALS, CONGENIC; AORTA; BLOOD PRESSURE; CYCLOPENTANES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENOTYPE; GLYCOSAMINOGLYCANS; HYPERTENSION; LIPID PEROXIDATION; OXIDATIVE STRESS; PHENYLEPHRINE; QUINOLINES; RATS, TRANSGENIC; RECEPTORS, G-PROTEIN-COUPLED; RENIN; SODIUM CHLORIDE, DIETARY; TIME FACTORS; VASCULAR REMODELING;

EID: 84983631366     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00631.2015     Document Type: Article

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