Enzyme Sequestration as a Tuning Point in Controlling Response Dynamics of Signalling Networks

PLoS Computational Biology

Volumn 12, Issue 5, 2016, Pages

  Feng, Song ^a   Ollivier, Julien F ^b   Soyer, Orkun S ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b Biojazz Research   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; DECISION MAKING; SCAFFOLDS (BIOLOGY); TUNING;

ADAPTIVE RESPONSE; COMBINATORIAL INTERACTIONS; DECISIONS MAKINGS; DESIGN PRINCIPLES; DESIGN SPACES; EVOLUTIONARY SIMULATIONS; IN-SILICO; SCAFFOLDING PROTEINS; SIGNALING NETWORKS; ULTRASENSITIVE;

ENZYMES;

SCAFFOLD PROTEIN; ENZYME; PROTEIN;

ADAPTIVE RESPONSE DYNAMICS; ALLOSTERISM; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DYNAMICS; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SATURATION; ENZYME SEQUESTRATION; EVOLUTION; PROTEIN INTERACTION; SIGNALLING NETWORK; SIMULATION; ULTRASENSITIVITY; ALGORITHM; BIOLOGICAL MODEL; BIOLOGY; COMPUTER SIMULATION; KINETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SYNTHETIC BIOLOGY;

ALGORITHMS; ALLOSTERIC REGULATION; BIOLOGICAL EVOLUTION; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; ENZYMES; KINETICS; MODELS, BIOLOGICAL; PROTEINS; SIGNAL TRANSDUCTION; SYNTHETIC BIOLOGY;

EID: 84975883878     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004918     Document Type: Article

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