메뉴 건너뛰기




Volumn 109, Issue 50, 2012, Pages E3513-E3522

Ultrasensitivity of the Bacillus subtilis sporulation decision

Author keywords

Cell fate; Development; Differentiation; Network; Stochasticity

Indexed keywords

BACTERIAL PROTEIN; PHOSPHORELAY KINASE KINA; PROTEIN SPO0A; SIGMA FACTOR; SIGMA FACTOR E; SIGMA FACTOR F; UNCLASSIFIED DRUG; BACTERIAL DNA; FLIA PROTEIN, BACTERIA; KINA PROTEIN, BACILLUS SUBTILIS; PROTEIN KINASE; SPO0A PROTEIN, BACILLUS SUBTILIS; SPORULATION SPECIFIC SIGMA FACTORS; SPORULATION-SPECIFIC SIGMA FACTORS; TRANSCRIPTION FACTOR;

EID: 84874412536     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213974109     Document Type: Article
Times cited : (56)

References (63)
  • 1
    • 1842613501 scopus 로고    scopus 로고
    • Regulation of endospore formation in bacillus subtilis
    • Errington J (2003) Regulation of endospore formation in Bacillus subtilis. Nat Rev Microbiol 1(2):117–126.
    • (2003) Nat Rev Microbiol , vol.1 , Issue.2 , pp. 117-126
    • Errington, J.1
  • 2
    • 0033818517 scopus 로고    scopus 로고
    • Resistance of bacillus endospores to extreme terrestrial and extraterrestrial environments
    • Nicholson WL, Munakata N, Horneck G, Melosh HJ, Setlow P (2000) Resistance of Bacillus endospores to extreme terrestrial and extraterrestrial environments. Microbiol Mol Biol Rev 64(3):548–572.
    • (2000) Microbiol Mol Biol Rev , vol.64 , Issue.3 , pp. 548-572
    • Nicholson, W.L.1    Munakata, N.2    Horneck, G.3    Melosh, H.J.4    Setlow, P.5
  • 3
    • 0027465228 scopus 로고
    • Bacillus subtilis sporulation: Regulation of gene expression and control of morphogenesis
    • Errington J (1993) Bacillus subtilis sporulation: Regulation of gene expression and control of morphogenesis. Microbiol Rev 57(1):1–33.
    • (1993) Microbiol Rev , vol.57 , Issue.1 , pp. 1-33
    • Errington, J.1
  • 4
    • 0034608820 scopus 로고    scopus 로고
    • The transcriptional profile of early to middle sporulation in bacillus subtilis
    • Fawcett P, Eichenberger P, Losick R, Youngman P (2000) The transcriptional profile of early to middle sporulation in Bacillus subtilis. Proc Natl Acad Sci USA 97(14): 8063–8068.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.14 , pp. 8063-8068
    • Fawcett, P.1    Eichenberger, P.2    Losick, R.3    Youngman, P.4
  • 5
    • 0037432566 scopus 로고    scopus 로고
    • The sigmae regulon and the identification of additional sporulation genes in bacillus subtilis
    • Eichenberger P, et al. (2003) The sigmaE regulon and the identification of additional sporulation genes in Bacillus subtilis. J Mol Biol 327(5):945–972.
    • (2003) J Mol Biol , vol.327 , Issue.5 , pp. 945-972
    • Eichenberger, P.1
  • 6
    • 33645097172 scopus 로고    scopus 로고
    • The forespore line of gene expression in bacillus subtilis
    • Wang ST, et al. (2006) The forespore line of gene expression in Bacillus subtilis. J Mol Biol 358(1):16–37.
    • (2006) J Mol Biol , vol.358 , Issue.1 , pp. 16-37
    • Wang, S.T.1
  • 7
    • 0017060173 scopus 로고
    • Genetic aspects of bacterial endospore formation
    • Piggot PJ, Coote JG (1976) Genetic aspects of bacterial endospore formation. Bacteriol Rev 40(4):908–962.
    • (1976) Bacteriol Rev , vol.40 , Issue.4 , pp. 908-962
    • Piggot, P.J.1    Coote, J.G.2
  • 8
    • 2942616403 scopus 로고    scopus 로고
    • Compartmentalization of gene expression during bacillus subtilis spore formation
    • Hilbert DW, Piggot PJ (2004) Compartmentalization of gene expression during Bacillus subtilis spore formation. Microbiol Mol Biol Rev 68(2):234–262.
    • (2004) Microbiol Mol Biol Rev , vol.68 , Issue.2 , pp. 234-262
    • Hilbert, D.W.1    Piggot, P.J.2
  • 9
    • 0346256789 scopus 로고    scopus 로고
    • The spo0a regulon of bacillus subtilis
    • Molle V, et al. (2003) The Spo0A regulon of Bacillus subtilis. Mol Microbiol 50(5): 1683–1701.
    • (2003) Mol Microbiol , vol.50 , Issue.5 , pp. 1683-1701
    • Molle, V.1
  • 10
    • 0027463845 scopus 로고
    • The phosphorelay signal transduction pathway in the initiation of bacillus subtilis sporulation
    • Hoch JA (1993) The phosphorelay signal transduction pathway in the initiation of Bacillus subtilis sporulation. J Cell Biochem 51(1):55–61.
    • (1993) J Cell Biochem , vol.51 , Issue.1 , pp. 55-61
    • Hoch, J.A.1
  • 11
    • 0027524272 scopus 로고
    • Regulation of the phosphorelay and the initiation of sporulation in bacillus subtilis
    • Hoch JA (1993) Regulation of the phosphorelay and the initiation of sporulation in Bacillus subtilis. Annu Rev Microbiol 47:441–465.
    • (1993) Annu Rev Microbiol , vol.47 , pp. 441-465
    • Hoch, J.A.1
  • 12
    • 0025964291 scopus 로고
    • Initiation of sporulation in b. Subtilis is controlled by a multicomponent phosphorelay
    • Burbulys D, Trach KA, Hoch JA (1991) Initiation of sporulation in B. subtilis is controlled by a multicomponent phosphorelay. Cell 64(3):545–552.
    • (1991) Cell , vol.64 , Issue.3 , pp. 545-552
    • Burbulys, D.1    Trach, K.A.2    Hoch, J.A.3
  • 13
    • 53849146767 scopus 로고    scopus 로고
    • Bistability, epigenetics, and bet-hedging in bacteria
    • Veening JW, Smits WK, Kuipers OP (2008) Bistability, epigenetics, and bet-hedging in bacteria. Annu Rev Microbiol 62:193–210.
    • (2008) Annu Rev Microbiol , vol.62 , pp. 193-210
    • Veening, J.W.1    Smits, W.K.2    Kuipers, O.P.3
  • 14
    • 75849116320 scopus 로고    scopus 로고
    • Deciding fate in adverse times: Sporulation and competence in bacillus subtilis
    • Schultz D, Wolynes PG, Ben Jacob E, Onuchic JN (2009) Deciding fate in adverse times: Sporulation and competence in Bacillus subtilis. Proc Natl Acad Sci USA 106(50): 21027–21034.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.50 , pp. 21027-21034
    • Schultz, D.1    Wolynes, P.G.2    Ben Jacob, E.3    Onuchic, J.N.4
  • 15
    • 66149121458 scopus 로고    scopus 로고
    • Complexity in bacterial cell-cell communication: Quorum signal integration and subpopulation signaling in the bacillus subtilis phosphorelay
    • Bischofs IB, Hug JA, Liu AW, Wolf DM, Arkin AP (2009) Complexity in bacterial cell-cell communication: Quorum signal integration and subpopulation signaling in the Bacillus subtilis phosphorelay. Proc Natl Acad Sci USA 106(16):6459–6464.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.16 , pp. 6459-6464
    • Bischofs, I.B.1    Hug, J.A.2    Liu, A.W.3    Wolf, D.M.4    Arkin, A.P.5
  • 16
    • 77952417100 scopus 로고    scopus 로고
    • Broadly heterogeneous activation of the master regulator for sporulation in bacillus subtilis
    • Chastanet A, et al. (2010) Broadly heterogeneous activation of the master regulator for sporulation in Bacillus subtilis. Proc Natl Acad Sci USA 107(18):8486–8491.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.18 , pp. 8486-8491
    • Chastanet, A.1
  • 17
    • 77950668896 scopus 로고    scopus 로고
    • Heterochronic phosphorelay gene expression as a source of heterogeneity in bacillus subtilis spore formation
    • de Jong IG, Veening JW, Kuipers OP (2010) Heterochronic phosphorelay gene expression as a source of heterogeneity in Bacillus subtilis spore formation. J Bacteriol 192(8):2053–2067.
    • (2010) J Bacteriol , vol.192 , Issue.8 , pp. 2053-2067
    • De Jong, I.G.1    Veening, J.W.2    Kuipers, O.P.3
  • 18
    • 35748955855 scopus 로고    scopus 로고
    • Model-based definition of population heterogeneity and its effects on metabolism in sporulating bacillus subtilis
    • Morohashi M, et al. (2007) Model-based definition of population heterogeneity and its effects on metabolism in sporulating Bacillus subtilis. J Biochem 142(2):183–191.
    • (2007) J Biochem , vol.142 , Issue.2 , pp. 183-191
    • Morohashi, M.1
  • 19
    • 0037133943 scopus 로고    scopus 로고
    • Asymmetric cell division in b. Subtilis involves a spiral-like intermediate of the cytokinetic protein ftsz
    • Ben-Yehuda S, Losick R (2002) Asymmetric cell division in B. subtilis involves a spiral-like intermediate of the cytokinetic protein FtsZ. Cell 109(2):257–266.
    • (2002) Cell , vol.109 , Issue.2 , pp. 257-266
    • Ben-Yehuda, S.1    Losick, R.2
  • 20
    • 0029918758 scopus 로고    scopus 로고
    • Transcription factor spo0a switches the localization of the cell division protein ftsz from a medial to a bipolar pattern in bacillus subtilis
    • Levin PA, Losick R (1996) Transcription factor Spo0A switches the localization of the cell division protein FtsZ from a medial to a bipolar pattern in Bacillus subtilis. Genes Dev 10(4):478–488.
    • (1996) Genes Dev , vol.10 , Issue.4 , pp. 478-488
    • Levin, P.A.1    Losick, R.2
  • 21
    • 77955393111 scopus 로고    scopus 로고
    • Single-cell measurement of the levels and distributions of the phosphorelay components in a population of sporulating bacillus subtilis cells
    • Eswaramoorthy P, Dinh J, Duan D, Igoshin OA, Fujita M (2010) Single-cell measurement of the levels and distributions of the phosphorelay components in a population of sporulating Bacillus subtilis cells. Microbiology 156(Pt 8):2294–2304.
    • (2010) Microbiology , vol.156 , pp. 2294-2304
    • Eswaramoorthy, P.1    Dinh, J.2    Duan, D.3    Igoshin, O.A.4    Fujita, M.5
  • 23
    • 18844448417 scopus 로고    scopus 로고
    • Developmental commitment in a bacterium
    • Dworkin J, Losick R (2005) Developmental commitment in a bacterium. Cell 121(3): 401–409.
    • (2005) Cell , vol.121 , Issue.3 , pp. 401-409
    • Dworkin, J.1    Losick, R.2
  • 24
    • 81355164151 scopus 로고    scopus 로고
    • Reversible and noisy progression towards a commitment point enables adaptable and reliable cellular decision-making
    • Kuchina A, Espinar L, Garcia-Ojalvo J, Süel GM (2011) Reversible and noisy progression towards a commitment point enables adaptable and reliable cellular decision-making. PLOS Comput Biol 7(11):e1002273.
    • (2011) PLOS Comput Biol , vol.7 , Issue.11
    • Kuchina, A.1    Espinar, L.2    Garcia-Ojalvo, J.3    Süel, G.M.4
  • 25
    • 79958055746 scopus 로고    scopus 로고
    • Regulation of growth of the mother cell and chromosome replication during sporulation of bacillus subtilis
    • Xenopoulos P, Piggot PJ (2011) Regulation of growth of the mother cell and chromosome replication during sporulation of Bacillus subtilis. J Bacteriol 193 (12):3117–3126.
    • (2011) J Bacteriol , vol.193 , Issue.12 , pp. 3117-3126
    • Xenopoulos, P.1    Piggot, P.J.2
  • 26
    • 77952903892 scopus 로고    scopus 로고
    • Rewiring cells: Synthetic biology as a tool to interrogate the organizational principles of living systems
    • Bashor CJ, Horwitz AA, Peisajovich SG, Lim WA (2010) Rewiring cells: Synthetic biology as a tool to interrogate the organizational principles of living systems. Annu Rev Biophys 39:515–537.
    • (2010) Annu Rev Biophys , vol.39 , pp. 515-537
    • Bashor, C.J.1    Horwitz, A.A.2    Peisajovich, S.G.3    Lim, W.A.4
  • 27
    • 77955302838 scopus 로고    scopus 로고
    • The threshold level of the sensor histidine kinase kina governs entry into sporulation in bacillus subtilis
    • Eswaramoorthy P, et al. (2010) The threshold level of the sensor histidine kinase KinA governs entry into sporulation in Bacillus subtilis. J Bacteriol 192(15):3870–3882.
    • (2010) J Bacteriol , vol.192 , Issue.15 , pp. 3870-3882
    • Eswaramoorthy, P.1
  • 28
    • 24944483644 scopus 로고    scopus 로고
    • Evidence that entry into sporulation in bacillus subtilis is governed by a gradual increase in the level and activity of the master regulator spo0a
    • Fujita M, Losick R (2005) Evidence that entry into sporulation in Bacillus subtilis is governed by a gradual increase in the level and activity of the master regulator Spo0A. Genes Dev 19(18):2236–2244.
    • (2005) Genes Dev , vol.19 , Issue.18 , pp. 2236-2244
    • Fujita, M.1    Losick, R.2
  • 29
    • 68949150876 scopus 로고    scopus 로고
    • An a257v mutation in the bacillus subtilis response regulator spo0a prevents regulated expression of promoters with low-consensus binding sites
    • Seredick SD, Seredick BM, Baker D, Spiegelman GB (2009) An A257V mutation in the bacillus subtilis response regulator Spo0A prevents regulated expression of promoters with low-consensus binding sites. J Bacteriol 191(17):5489–5498.
    • (2009) J Bacteriol , vol.191 , Issue.17 , pp. 5489-5498
    • Seredick, S.D.1    Seredick, B.M.2    Baker, D.3    Spiegelman, G.B.4
  • 30
    • 0025674203 scopus 로고
    • Control of developmental transcription factor sigma f by sporulation regulatory proteins spoiiaa and spoiiab in bacillus subtilis
    • Schmidt R, et al. (1990) Control of developmental transcription factor sigma F by sporulation regulatory proteins SpoIIAA and SpoIIAB in Bacillus subtilis. Proc Natl Acad Sci USA 87(23):9221–9225.
    • (1990) Proc Natl Acad Sci USA , vol.87 , Issue.23 , pp. 9221-9225
    • Schmidt, R.1
  • 31
    • 0030605510 scopus 로고    scopus 로고
    • Control of the cell-specificity of sigma f activity in bacillus subtilis
    • Errington J, et al. (1996) Control of the cell-specificity of sigma F activity in Bacillus subtilis. Philos Trans R Soc Lond B Biol Sci 351(1339):537–542.
    • (1996) Philos Trans R Soc Lond B Biol Sci , vol.351 , Issue.1339 , pp. 537-542
    • Errington, J.1
  • 32
    • 4444312872 scopus 로고    scopus 로고
    • Efficient regulation of sigmaf, the first sporulation-specific sigma factor in b. Subtilis
    • Clarkson J, Campbell ID, Yudkin MD (2004) Efficient regulation of sigmaF, the first sporulation-specific sigma factor in B. subtilis. J Mol Biol 342(4):1187–1195.
    • (2004) J Mol Biol , vol.342 , Issue.4 , pp. 1187-1195
    • Clarkson, J.1    Campbell, I.D.2    Yudkin, M.D.3
  • 33
    • 33744976080 scopus 로고    scopus 로고
    • The mechanism of cell differentiation in bacillus subtilis
    • Iber D, Clarkson J, Yudkin MD, Campbell ID (2006) The mechanism of cell differentiation in Bacillus subtilis. Nature 441(7091):371–374.
    • (2006) Nature , vol.441 , Issue.7091 , pp. 371-374
    • Iber, D.1    Clarkson, J.2    Yudkin, M.D.3    Campbell, I.D.4
  • 34
    • 33745197543 scopus 로고    scopus 로고
    • Signalling network with a bistable hysteretic switch controls developmental activation of the sigma transcription factor in bacillus subtilis
    • Igoshin OA, Price CW, Savageau MA (2006) Signalling network with a bistable hysteretic switch controls developmental activation of the sigma transcription factor in Bacillus subtilis. Mol Microbiol 61(1):165–184.
    • (2006) Mol Microbiol , vol.61 , Issue.1 , pp. 165-184
    • Igoshin, O.A.1    Price, C.W.2    Savageau, M.A.3
  • 35
    • 0142027814 scopus 로고    scopus 로고
    • Structure and function of the feed-forward loop network motif
    • Mangan S, Alon U (2003) Structure and function of the feed-forward loop network motif. Proc Natl Acad Sci USA 100(21):11980–11985.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.21 , pp. 11980-11985
    • Mangan, S.1    Alon, U.2
  • 36
    • 0036290382 scopus 로고    scopus 로고
    • Dimer formation and transcription activation in the sporulation response regulator spo0a
    • Lewis RJ, et al. (2002) Dimer formation and transcription activation in the sporulation response regulator Spo0A. J Mol Biol 316(2):235–245.
    • (2002) J Mol Biol , vol.316 , Issue.2 , pp. 235-245
    • Lewis, R.J.1
  • 37
    • 14544290034 scopus 로고    scopus 로고
    • High- and low-threshold genes in the spo0a regulon of bacillus subtilis
    • Fujita M, González-Pastor JE, Losick R (2005) High- and low-threshold genes in the Spo0A regulon of Bacillus subtilis. J Bacteriol 187(4):1357–1368.
    • (2005) J Bacteriol , vol.187 , Issue.4 , pp. 1357-1368
    • Fujita, M.1    González-Pastor, J.E.2    Losick, R.3
  • 38
    • 67749117790 scopus 로고    scopus 로고
    • Partial penetrance facilitates developmental evolution in bacteria
    • Eldar A, et al. (2009) Partial penetrance facilitates developmental evolution in bacteria. Nature 460(7254):510–514.
    • (2009) Nature , vol.460 , Issue.7254 , pp. 510-514
    • Eldar, A.1
  • 39
    • 0037739975 scopus 로고    scopus 로고
    • The master regulator for entry into sporulation in bacillus subtilis becomes a cell-specific transcription factor after asymmetric division
    • Fujita M, Losick R (2003) The master regulator for entry into sporulation in Bacillus subtilis becomes a cell-specific transcription factor after asymmetric division. Genes Dev 17(9):1166–1174.
    • (2003) Genes Dev , vol.17 , Issue.9 , pp. 1166-1174
    • Fujita, M.1    Losick, R.2
  • 40
    • 0028787402 scopus 로고
    • Extracellular signal protein triggering the proteolytic activation of a developmental transcription factor in b. Subtilis
    • Hofmeister AE, Londoño-Vallejo A, Harry E, Stragier P, Losick R (1995) Extracellular signal protein triggering the proteolytic activation of a developmental transcription factor in B. subtilis. Cell 83(2):219–226.
    • (1995) Cell , vol.83 , Issue.2 , pp. 219-226
    • Hofmeister, A.E.1    Londoño-Vallejo, A.2    Harry, E.3    Stragier, P.4    Losick, R.5
  • 41
    • 0036192373 scopus 로고    scopus 로고
    • An investigation into the compartmentalization of the sporulation transcription factor sigmae in bacillus subtilis
    • Fujita M, Losick R (2002) An investigation into the compartmentalization of the sporulation transcription factor sigmaE in Bacillus subtilis. Mol Microbiol 43(1):27–38.
    • (2002) Mol Microbiol , vol.43 , Issue.1 , pp. 27-38
    • Fujita, M.1    Losick, R.2
  • 42
    • 0035725455 scopus 로고    scopus 로고
    • A three-protein inhibitor of polar septation during sporulation in bacillus subtilis
    • Eichenberger P, Fawcett P, Losick R (2001) A three-protein inhibitor of polar septation during sporulation in Bacillus subtilis. Mol Microbiol 42(5):1147–1162.
    • (2001) Mol Microbiol , vol.42 , Issue.5 , pp. 1147-1162
    • Eichenberger, P.1    Fawcett, P.2    Losick, R.3
  • 43
    • 79952638264 scopus 로고    scopus 로고
    • Cellular decision making and biological noise: From microbes to mammals
    • Balázsi G, van Oudenaarden A, Collins JJ (2011) Cellular decision making and biological noise: from microbes to mammals. Cell 144(6):910–925.
    • (2011) Cell , vol.144 , Issue.6 , pp. 910-925
    • Balázsi, G.1    Van Oudenaarden, A.2    Collins, J.J.3
  • 44
    • 0030034983 scopus 로고    scopus 로고
    • Cell cycle control by an essential bacterial two-component signal transduction protein
    • Quon KC, Marczynski GT, Shapiro L (1996) Cell cycle control by an essential bacterial two-component signal transduction protein. Cell 84(1):83–93.
    • (1996) Cell , vol.84 , Issue.1 , pp. 83-93
    • Quon, K.C.1    Marczynski, G.T.2    Shapiro, L.3
  • 45
    • 0028940059 scopus 로고
    • Comk encodes the competence transcription factor, the key regulatory protein for competence development in bacillus subtilis
    • van Sinderen D, et al. (1995) comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis. Mol Microbiol 15(3):455–462.
    • (1995) Mol Microbiol , vol.15 , Issue.3 , pp. 455-462
    • Van Sinderen, D.1
  • 46
    • 80051720034 scopus 로고    scopus 로고
    • Distinct interactions select and maintain a specific cell fate
    • Doncic A, Falleur-Fettig M, Skotheim JM (2011) Distinct interactions select and maintain a specific cell fate. Mol Cell 43(4):528–539.
    • (2011) Mol Cell , vol.43 , Issue.4 , pp. 528-539
    • Doncic, A.1    Falleur-Fettig, M.2    Skotheim, J.M.3
  • 47
    • 33748058888 scopus 로고    scopus 로고
    • Bistability in bacteria
    • Dubnau D, Losick R (2006) Bistability in bacteria. Mol Microbiol 61(3):564–572.
    • (2006) Mol Microbiol , vol.61 , Issue.3 , pp. 564-572
    • Dubnau, D.1    Losick, R.2
  • 48
    • 77952093377 scopus 로고    scopus 로고
    • The scaffold protein ste5 directly controls a switch-like mating decision in yeast
    • Malleshaiah MK, Shahrezaei V, Swain PS, Michnick SW (2010) The scaffold protein Ste5 directly controls a switch-like mating decision in yeast. Nature 465(7294): 101–105.
    • (2010) Nature , vol.465 , Issue.7294 , pp. 101-105
    • Malleshaiah, M.K.1    Shahrezaei, V.2    Swain, P.S.3    Michnick, S.W.4
  • 49
    • 33746931732 scopus 로고    scopus 로고
    • Threshold responses to morphogen gradients by zero-order ultrasensitivity
    • 2005.0028
    • Melen GJ, Levy S, Barkai N, Shilo BZ (2005) Threshold responses to morphogen gradients by zero-order ultrasensitivity. Mol Syst Biol 1:2005.0028.
    • (2005) Mol Syst Biol , vol.1
    • Melen, G.J.1    Levy, S.2    Barkai, N.3    Shilo, B.Z.4
  • 50
    • 77955502318 scopus 로고    scopus 로고
    • Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate
    • Narula J, Smith AM, Gottgens B, Igoshin OA (2010) Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate. PLOS Comput Biol 6(5):e1000771.
    • (2010) PLOS Comput Biol , vol.6 , Issue.5
    • Narula, J.1    Smith, A.M.2    Gottgens, B.3    Igoshin, O.A.4
  • 51
    • 33645073688 scopus 로고    scopus 로고
    • Phenotypic variation in bacteria: The role of feedback regulation
    • Smits WK, Kuipers OP, Veening J-W (2006) Phenotypic variation in bacteria: The role of feedback regulation. Nat Rev Microbiol 4(4):259–271.
    • (2006) Nat Rev Microbiol , vol.4 , Issue.4 , pp. 259-271
    • Smits, W.K.1    Kuipers, O.P.2    Veening, J.-W.3
  • 52
    • 78349256632 scopus 로고    scopus 로고
    • The interplay of multiple feedback loops with post-translational kinetics results in bistability of mycobacterial stress response
    • Tiwari A, Balázsi G, Gennaro ML, Igoshin OA (2010) The interplay of multiple feedback loops with post-translational kinetics results in bistability of mycobacterial stress response. Phys Biol 7(3):036005.
    • (2010) Phys Biol , vol.7 , Issue.3 , pp. 036005
    • Tiwari, A.1    Balázsi, G.2    Gennaro, M.L.3    Igoshin, O.A.4
  • 53
    • 79954579296 scopus 로고    scopus 로고
    • Bistable responses in bacterial genetic networks: Designs and dynamical consequences
    • Tiwari A, Ray JC, Narula J, Igoshin OA (2011) Bistable responses in bacterial genetic networks: Designs and dynamical consequences. Math Biosci 231(1):76–89.
    • (2011) Math Biosci , vol.231 , Issue.1 , pp. 76-89
    • Tiwari, A.1    Ray, J.C.2    Narula, J.3    Igoshin, O.A.4
  • 54
    • 79957566441 scopus 로고    scopus 로고
    • An incoherent regulatory network architecture that orchestrates b cell diversification in response to antigen signaling
    • Sciammas R, et al. (2011) An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling. Mol Syst Biol 7:495.
    • (2011) Mol Syst Biol , vol.7 , pp. 495
    • Sciammas, R.1
  • 55
    • 80655125440 scopus 로고    scopus 로고
    • Just-in-time control of spo0a synthesis in bacillus subtilis by multiple regulatory mechanisms
    • Chastanet A, Losick R (2011) Just-in-time control of Spo0A synthesis in Bacillus subtilis by multiple regulatory mechanisms. J Bacteriol 193(22):6366–6374.
    • (2011) J Bacteriol , vol.193 , Issue.22 , pp. 6366-6374
    • Chastanet, A.1    Losick, R.2
  • 56
    • 0031821820 scopus 로고    scopus 로고
    • Feedback loops involving spo0a and abrb in in vitro transcription of the genes involved in the initiation of sporulation in bacillus subtilis
    • Fujita M, Sadaie Y (1998) Feedback loops involving Spo0A and AbrB in in vitro transcription of the genes involved in the initiation of sporulation in Bacillus subtilis. J Biochem 124(1):98–104.
    • (1998) J Biochem , vol.124 , Issue.1 , pp. 98-104
    • Fujita, M.1    Sadaie, Y.2
  • 57
    • 0032477825 scopus 로고    scopus 로고
    • Synergistic kinetic interactions between components of the phosphorelay controlling sporulation in bacillus subtilis
    • Grimshaw CE, et al. (1998) Synergistic kinetic interactions between components of the phosphorelay controlling sporulation in Bacillus subtilis. Biochemistry 37(5):1365–1375.
    • (1998) Biochemistry , vol.37 , Issue.5 , pp. 1365-1375
    • Grimshaw, C.E.1
  • 58
    • 80051950768 scopus 로고    scopus 로고
    • Stochkit2: Software for discrete stochastic simulation of biochemical systems with events
    • Sanft KR, et al. (2011) StochKit2: Software for discrete stochastic simulation of biochemical systems with events. Bioinformatics 27(17):2457–2458.
    • (2011) Bioinformatics , vol.27 , Issue.17 , pp. 2457-2458
    • Sanft, K.R.1
  • 59
    • 0030597337 scopus 로고    scopus 로고
    • Plasmids for ectopic integration in bacillus subtilis
    • Guérout-Fleury AM, Frandsen N, Stragier P (1996) Plasmids for ectopic integration in Bacillus subtilis. Gene 180(1-2):57–61.
    • (1996) Gene , vol.180 , Issue.1-2 , pp. 57-61
    • Guérout-Fleury, A.M.1    Frandsen, N.2    Stragier, P.3
  • 60
    • 8744302067 scopus 로고    scopus 로고
    • Visualization of differential gene expression by improved cyan fluorescent protein and yellow fluorescent protein production in bacillus subtilis
    • Veening JW, Smits WK, Hamoen LW, Jongbloed JD, Kuipers OP (2004) Visualization of differential gene expression by improved cyan fluorescent protein and yellow fluorescent protein production in Bacillus subtilis. Appl Environ Microbiol 70(11): 6809–6815.
    • (2004) Appl Environ Microbiol , vol.70 , Issue.11 , pp. 6809-6815
    • Veening, J.W.1    Smits, W.K.2    Hamoen, L.W.3    Jongbloed, J.D.4    Kuipers, O.P.5
  • 61
    • 0014533169 scopus 로고
    • Commitment to sporulation in bacillus subtilis and its relationship to development of actinomycin resistance
    • Sterlini JM, Mandelstam J (1969) Commitment to sporulation in Bacillus subtilis and its relationship to development of actinomycin resistance. Biochem J 113(1):29–37.
    • (1969) Biochem J , vol.113 , Issue.1 , pp. 29-37
    • Sterlini, J.M.1    Mandelstam, J.2
  • 62
    • 68949163861 scopus 로고    scopus 로고
    • In vivo domain-based functional analysis of the major sporulation sensor kinase, kina, in bacillus subtilis
    • Eswaramoorthy P, Guo T, Fujita M (2009) In vivo domain-based functional analysis of the major sporulation sensor kinase, KinA, in Bacillus subtilis. J Bacteriol 191(17): 5358–5368.
    • (2009) J Bacteriol , vol.191 , Issue.17 , pp. 5358-5368
    • Eswaramoorthy, P.1    Guo, T.2    Fujita, M.3
  • 63
    • 80355131554 scopus 로고    scopus 로고
    • Live cell imaging of bacillus subtilis and streptococcus pneumoniae using automated time-lapse microscopy
    • pii: 3145
    • de Jong IG, Beilharz K, Kuipers OP, Veening JW (2011) Live Cell Imaging of Bacillus subtilis and Streptococcus pneumoniae using Automated Time-lapse Microscopy. J Vis Exp 53:pii: 3145, doi: 10.3791/3145.
    • (2011) J Vis Exp , vol.53
    • De Jong, I.G.1    Beilharz, K.2    Kuipers, O.P.3    Veening, J.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.