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Volumn 5, Issue , 2009, Pages

Protein sequestration generates a flexible ultrasensitive response in a genetic network

Author keywords

All or none; Inhibitor; Threshold; Titration; Transcription

Indexed keywords

HOMODIMER; LEUCINE ZIPPER PROTEIN; TRANSCRIPTION FACTOR; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; FUNGAL PROTEIN; TRANSACTIVATOR PROTEIN;

EID: 67149138163     PISSN: 17444292     EISSN: 17444292     Source Type: Journal    
DOI: 10.1038/msb.2009.30     Document Type: Article
Times cited : (198)

References (47)
  • 2
    • 0025238437 scopus 로고
    • The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
    • Benezra R, Davis RL, Lockshon D, Turner DL, Weintraub H (1990) The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 61: 49-59
    • (1990) Cell , vol.61 , pp. 49-59
    • Benezra, R.1    Davis, R.L.2    Lockshon, D.3    Turner, D.L.4    Weintraub, H.5
  • 4
    • 56949098506 scopus 로고    scopus 로고
    • Molecular titration and ultrasensitivity in regulatory networks
    • Buchler NE, Louis M (2008) Molecular titration and ultrasensitivity in regulatory networks. J Mol Biol 384: 1106-1119
    • (2008) J Mol Biol , vol.384 , pp. 1106-1119
    • Buchler, N.E.1    Louis, M.2
  • 6
    • 0032531831 scopus 로고    scopus 로고
    • Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo
    • Burz DS, Rivera-Pomar R, Jackle H, Hanes SD (1998) Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo. EMBO J 17: 5998-6009
    • (1998) EMBO J , vol.17 , pp. 5998-6009
    • Burz, D.S.1    Rivera-Pomar, R.2    Jackle, H.3    Hanes, S.D.4
  • 7
    • 33748058888 scopus 로고    scopus 로고
    • Bistability in bacteria
    • Dubnau D, Losick R (2006) Bistability in bacteria. Mol Microbiol 61: 564-572
    • (2006) Mol Microbiol , vol.61 , pp. 564-572
    • Dubnau, D.1    Losick, R.2
  • 8
    • 0030445778 scopus 로고    scopus 로고
    • Tripping the switch fantastic: How a protein kinase cascade can convert graded inputs into switch-like outputs
    • Ferrell Jr JE (1996) Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs. Trends Biochem Sci 21: 460-466
    • (1996) Trends Biochem Sci , vol.21 , pp. 460-466
    • Ferrell Jr, J.E.1
  • 9
    • 0031203921 scopus 로고    scopus 로고
    • How responses get more switch-like as you move down a protein kinase cascade
    • Ferrell Jr JE (1997) How responses get more switch-like as you move down a protein kinase cascade. Trends Biochem Sci 22: 288-289
    • (1997) Trends Biochem Sci , vol.22 , pp. 288-289
    • Ferrell Jr, J.E.1
  • 10
    • 0347635508 scopus 로고    scopus 로고
    • Design of genetic networks with specified functions by evolution in silico
    • Francois P, Hakim V (2004) Design of genetic networks with specified functions by evolution in silico. Proc Natl Acad Sci USA 101: 580-585
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 580-585
    • Francois, P.1    Hakim, V.2
  • 12
    • 0023805741 scopus 로고
    • Negative effect of the transcriptional activator GAL4
    • Gill G, Ptashne M (1988) Negative effect of the transcriptional activator GAL4. Nature 334: 721-724
    • (1988) Nature , vol.334 , pp. 721-724
    • Gill, G.1    Ptashne, M.2
  • 13
    • 0020171028 scopus 로고
    • Sensitivity amplification in biochemical systems
    • Goldbeter A, Koshland Jr DE (1982) Sensitivity amplification in biochemical systems. Q Rev Biophys 15: 555-591
    • (1982) Q Rev Biophys , vol.15 , pp. 555-591
    • Goldbeter, A.1    Koshland Jr, D.E.2
  • 14
    • 0021715523 scopus 로고
    • Ultrasensitivity in biochemical systems controlled by covalent modification. Interplay between zero-order and multistep effects
    • Goldbeter A, Koshland Jr DE (1984) Ultrasensitivity in biochemical systems controlled by covalent modification. Interplay between zero-order and multistep effects. J Biol Chem 259:14441-14447
    • (1984) J Biol Chem , vol.259 , pp. 14441-14447
    • Goldbeter, A.1    Koshland Jr, D.E.2
  • 15
    • 34447099234 scopus 로고    scopus 로고
    • Probing the limits to positional information
    • Gregor T, Tank DW, Wieschaus EF, Bialek W (2007) Probing the limits to positional information. Cell 130: 153-164
    • (2007) Cell , vol.130 , pp. 153-164
    • Gregor, T.1    Tank, D.W.2    Wieschaus, E.F.3    Bialek, W.4
  • 16
    • 26844571282 scopus 로고    scopus 로고
    • Multisite protein phosphorylation makes a good threshold but can be a poor switch
    • Gunawardena J (2005) Multisite protein phosphorylation makes a good threshold but can be a poor switch. Proc Natl Acad Sci USA 102: 14617-14622
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14617-14622
    • Gunawardena, J.1
  • 17
    • 0023239517 scopus 로고
    • Functional inactivation of genes by dominant negative mutations
    • Herskowitz I (1987) Functional inactivation of genes by dominant negative mutations. Nature 329: 219-222
    • (1987) Nature , vol.329 , pp. 219-222
    • Herskowitz, I.1
  • 18
    • 14844358192 scopus 로고    scopus 로고
    • Ultrasensitivity and noise propagation in a synthetic transcriptional cascade
    • Hooshangi S, Thiberge S, Weiss R (2005) Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. Proc Natl Acad Sci USA 102: 3581-3586
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3581-3586
    • Hooshangi, S.1    Thiberge, S.2    Weiss, R.3
  • 20
    • 0031559933 scopus 로고    scopus 로고
    • Quantification of information transfer via cellular signal transduction pathways
    • Kholodenko BN, Hoek JB, Westerhoff HV, Brown GC (1997) Quantification of information transfer via cellular signal transduction pathways. FEBS Lett 414: 430-434
    • (1997) FEBS Lett , vol.414 , pp. 430-434
    • Kholodenko, B.N.1    Hoek, J.B.2    Westerhoff, H.V.3    Brown, G.C.4
  • 21
    • 55549113874 scopus 로고    scopus 로고
    • A quantitative model of transcription factor-activated gene expression
    • Kim HD, O'Shea EK (2008) A quantitative model of transcription factor-activated gene expression. Nat Struct Mol Biol 15:1192-1198
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 1192-1198
    • Kim, H.D.1    O'Shea, E.K.2
  • 22
    • 33947304756 scopus 로고    scopus 로고
    • Substrate competition as a source of ultrasensitivity in the inactivation of Wee1
    • Kim SY, Ferrell Jr JE (2007) Substrate competition as a source of ultrasensitivity in the inactivation of Wee1. Cell 128: 1133-1145
    • (2007) Cell , vol.128 , pp. 1133-1145
    • Kim, S.Y.1    Ferrell Jr, J.E.2
  • 24
    • 0028786167 scopus 로고
    • Extending dimerization interfaces: The bZIP basic region can form a coiled coil
    • Krylov D, Olive M, Vinson C (1995) Extending dimerization interfaces: the bZIP basic region can form a coiled coil. EMBO J 14: 5329-5337
    • (1995) EMBO J , vol.14 , pp. 5329-5337
    • Krylov, D.1    Olive, M.2    Vinson, C.3
  • 25
    • 0021741048 scopus 로고
    • The branch point effect. Ultrasensitivity and subsensitivity to metabolic control
    • LaPorte DC, Walsh K, Koshland Jr DE (1984) The branch point effect. Ultrasensitivity and subsensitivity to metabolic control. J Biol Chem 259:14068-14075
    • (1984) J Biol Chem , vol.259 , pp. 14068-14075
    • LaPorte, D.C.1    Walsh, K.2    Koshland Jr, D.E.3
  • 26
    • 23844525556 scopus 로고    scopus 로고
    • Quantitative analysis of ultrasensitive responses
    • Legewie S, Bluthgen N, Herzel H (2005a) Quantitative analysis of ultrasensitive responses. FEBS J 272: 4071-4079
    • (2005) FEBS J , vol.272 , pp. 4071-4079
    • Legewie, S.1    Bluthgen, N.2    Herzel, H.3
  • 27
    • 36248946925 scopus 로고    scopus 로고
    • Ultrasensitization: Switch-like regulation of cellular signaling by transcriptional induction
    • Legewie S, Bluthgen N, Schafer R, Herzel H (2005b) Ultrasensitization: switch-like regulation of cellular signaling by transcriptional induction. PLoS Comput Biol 1: e54
    • (2005) PLoS Comput Biol , vol.1
    • Legewie, S.1    Bluthgen, N.2    Schafer, R.3    Herzel, H.4
  • 28
    • 55949097145 scopus 로고    scopus 로고
    • Small RNAs establish delays and temporal thresholds in gene expression
    • Legewie S, Dienst D, Wilde A, Herzel H, Axmann IM (2008) Small RNAs establish delays and temporal thresholds in gene expression. Biophys J 95:3232-3238
    • (2008) Biophys J , vol.95 , pp. 3232-3238
    • Legewie, S.1    Dienst, D.2    Wilde, A.3    Herzel, H.4    Axmann, I.M.5
  • 29
    • 3142564584 scopus 로고    scopus 로고
    • The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae
    • Lenz DH, Mok KC, Lilley BN, Kulkarni RV, Wingreen NS, Bassler BL (2004) The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae. Cell 118: 69-82
    • (2004) Cell , vol.118 , pp. 69-82
    • Lenz, D.H.1    Mok, K.C.2    Lilley, B.N.3    Kulkarni, R.V.4    Wingreen, N.S.5    Bassler, B.L.6
  • 30
    • 34548668642 scopus 로고    scopus 로고
    • Quantitative characteristics of gene regulation by small RNA
    • Levine E, Zhang Z, Kuhlman T, Hwa T (2007) Quantitative characteristics of gene regulation by small RNA. PLoS Biol 5: e229
    • (2007) PLoS Biol , vol.5
    • Levine, E.1    Zhang, Z.2    Kuhlman, T.3    Hwa, T.4
  • 31
    • 0022449017 scopus 로고
    • Determinator-inhibitor pairs as a mechanism for threshold setting in development: A possible function for pseudogenes
    • McCarrey JR, Riggs AD (1986) Determinator-inhibitor pairs as a mechanism for threshold setting in development: a possible function for pseudogenes. Proc Natl Acad Sci USA 83: 679-683
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 679-683
    • McCarrey, J.R.1    Riggs, A.D.2
  • 32
    • 54049118804 scopus 로고    scopus 로고
    • A quantitative comparison of sRNA-based and protein-based gene regulation
    • Mehta P, Goyal S, Wingreen NS (2008) A quantitative comparison of sRNA-based and protein-based gene regulation. Mol Syst Biol 4:221
    • (2008) Mol Syst Biol , vol.4 , pp. 221
    • Mehta, P.1    Goyal, S.2    Wingreen, N.S.3
  • 34
  • 35
    • 0033568251 scopus 로고    scopus 로고
    • A strong carbon source effect is mediated by pUC plasmid sequences in a series of classical yeast vectors designed for promoter characterization
    • Pauwels K, Abadjieva A, Hilven P, Crabeel M (1999) A strong carbon source effect is mediated by pUC plasmid sequences in a series of classical yeast vectors designed for promoter characterization. Yeast 15: 1269-1274
    • (1999) Yeast , vol.15 , pp. 1269-1274
    • Pauwels, K.1    Abadjieva, A.2    Hilven, P.3    Crabeel, M.4
  • 36
    • 15544388848 scopus 로고    scopus 로고
    • Noise propagation in gene networks
    • Pedraza JM, van Oudenaarden A (2005) Noise propagation in gene networks. Science 307:1965-1969
    • (2005) Science , vol.307 , pp. 1965-1969
    • Pedraza, J.M.1    van Oudenaarden, A.2
  • 41
    • 0024977417 scopus 로고
    • Elevated recombination rates in transcriptionally active DNA
    • Thomas BJ, Rothstein R (1989) Elevated recombination rates in transcriptionally active DNA. Cell 56: 619-630
    • (1989) Cell , vol.56 , pp. 619-630
    • Thomas, B.J.1    Rothstein, R.2
  • 42
    • 0025778902 scopus 로고
    • The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes
    • Van Doren M, Ellis HM, Posakony JW (1991) The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes. Development 113: 245-255
    • (1991) Development , vol.113 , pp. 245-255
    • Van Doren, M.1    Ellis, H.M.2    Posakony, J.W.3
  • 44
    • 0032556443 scopus 로고    scopus 로고
    • On the relationship between genomic regulatory element organization and gene regulatory dynamics
    • Wolf DM, Eeckman FH (1998) On the relationship between genomic regulatory element organization and gene regulatory dynamics. J Theor Biol 195: 167-186
    • (1998) J Theor Biol , vol.195 , pp. 167-186
    • Wolf, D.M.1    Eeckman, F.H.2
  • 45
    • 21344437987 scopus 로고    scopus 로고
    • BMP antagonists: Their roles in development and involvement in pathophysiology
    • Yanagita M (2005) BMP antagonists: their roles in development and involvement in pathophysiology. Cytokine Growth Factor Rev 16: 309-317
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 309-317
    • Yanagita, M.1
  • 47
    • 0035458732 scopus 로고    scopus 로고
    • Time zones: A comparative genetics of circadian clocks
    • Young MW, Kay SA (2001) Time zones: a comparative genetics of circadian clocks. Nat Rev Genet 2: 702-715
    • (2001) Nat Rev Genet , vol.2 , pp. 702-715
    • Young, M.W.1    Kay, S.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.