Conformational control of the Ste5 scaffold protein insulates against MAP kinase misactivation

Science

Volumn 337, Issue 6099, 2012, Pages 1218-1222

  Zalatan, Jesse G ^a   Coyle, Scott M ^a,b   Rajan, Saravanan ^c   Sidhu, Sachdev S ^c   Lim, Wendell A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PLECKSTRIN; SCAFFOLD PROTEIN; SCAFFOLD PROTEIN STE5; SEX PHEROMONE; UNCLASSIFIED DRUG;

CELL ORGANELLE; ENZYME ACTIVITY; HOMOLOGY; MEMBRANE; MOLECULAR ANALYSIS; PHYSIOLOGICAL RESPONSE; PROTEIN; YEAST;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; MATING; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; YEAST;

EID: 84865811090     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1220683     Document Type: Article

References (28)

1. S. S. Taylor et al., Trends Biochem. Sci. 18, 84 (1993).
2. M. A. Schwartz, H. D. Madhani, Annu. Rev. Genet. 38, 725 (2004).
3. M. S. Qi, E. A. Elion, J. Cell Sci. 118, 3569 (2005).
4. M. C. Good, J. G. Zalatan, W. A. Lim, Science 332, 680 (2011).
5. D. K. Morrison, R. J. Davis, Annu. Rev. Cell Dev. Biol. 19, 91 (2003).
6. A. S. Shaw, E. L. Filbert, Nat. Rev. Immunol. 9, 47 (2009).
7. H. Saito, Curr. Opin. Microbiol. 13, 677 (2010).
8. D. N. Dhanasekaran, K. Kashef, C. M. Lee, H. Xu, E. P. Reddy, Oncogene 26, 3185 (2007).
9. K. Harris et al., Curr. Biol. 11, 1815 (2001).
10. W. R. Burack, A. S. Shaw, Curr. Opin. Cell Biol. 12, 211 (2000).
11. T. P. Garrington, G. L. Johnson, Curr. Opin. Cell Biol. 11, 211 (1999).
12. A. J. Whitmarsh, R. J. Davis, Trends Biochem. Sci. 23, 481 (1998).
13. T. Pawson, J. D. Scott, Science 278, 2075 (1997).
14. S. Marcus, A. Polverino, M. Barr, M. Wigler, Proc. Natl. Acad. Sci. U.S.A. 91, 7762 (1994).
15. K.-Y. Choi, B. Satterberg, D. M. Lyons, E. A. Elion, Cell 78, 499 (1994).
16. M. Good, G. Tang, J. Singleton, A. Reményi, W. A. Lim, Cell 136, 1085 (2009).
17. L. J. Flatauer, S. F. Zadeh, L. Bardwell, Mol. Cell. Biol. 25, 1793 (2005).
18. E. A. Elion, J. A. Brill, G. R. Fink, Proc. Natl. Acad. Sci. U.S.A. 88, 9392 (1991).
19. M. Z. Bao, M. A. Schwartz, G. T. Cantin, J. R. Yates 3rd, H. D. Madhani, Cell 119, 991 (2004).
20. S. Chou, L. Huang, H. P. Liu, Cell 119, 981 (2004).
21. L. Bardwell, Peptides 26, 339 (2005).
22. L. S. Garrenton, S. L. Young, J. Thorner, Genes Dev. 20, 1946 (2006).
23. C. Inouye, N. Dhillon, T. Durfee, P. C. Zambryski, J. Thorner, Genetics 147, 479 (1997).
24. R. E. Lamson, S. Takahashi, M. J. Winters, P. M. Pryciak, Curr. Biol. 16, 618 (2006).
25. C. Inouye, N. Dhillon, J. Thorner, Science 278, 103 (1997).
26. D. M. Lyons, S. K. Mahanty, K. Y. Choi, M. Manandhar, E. A. Elion, Mol. Cell. Biol. 16, 4095 (1996).
27. B. R. Cairns, S. W. Ramer, R. D. Kornberg, Genes Dev. 6, 1305 (1992).
28. G. Jansen, F. Bühring, C. P. Hollenberg, M. Ramezani Rad, Mol. Genet. Genomics 265, 102 (2001).