Redirecting carbon flux into malonyl-CoA to improve resveratrol titers: Proof of concept for genetic interventions predicted by OptForce computational framework

Chemical Engineering Science

Volumn 103, Issue , 2013, Pages 109-114

  Bhan, Namita ^a   Xu, Peng ^a   Khalidi, Omar ^a   Koffas, Mattheos A G ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Malonyl CoA; Metabolic engineering; OptForce; Resveratrol; Stoichiometric based modeling; Synthetic biology

Indexed keywords

ENZYMES; FATTY ACIDS; GENETIC ENGINEERING; METABOLIC ENGINEERING;

COMPUTATIONAL FRAMEWORK; GENETIC ALTERATIONS; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE; MALONYL-COA; OMEGA-3-FATTY ACIDS; OPTFORCE; PHOSPHOGLYCERATE KINASE; SYNTHETIC BIOLOGY;

RESVERATROL;

EID: 84879190343     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2012.10.009     Document Type: Article

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