In vivo co-localization of enzymes on RNA scaffolds increases metabolic production in a geometrically dependent manner

Nucleic Acids Research

Volumn 42, Issue 14, 2014, Pages 9493-9503

  Sachdeva, Gairik ^a,b,c   Garg, Abhishek ^b,e   Godding, David ^d   Way, Jeffrey C ^c   Silver, Pamela A ^b,c  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD UNIVERSITY   (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKANE; APTAMER; GREEN FLUORESCENT PROTEIN; HEXADECANOL; HYBRID PROTEIN; MOLECULAR SCAFFOLD; PENTADECANE; RNA SCAFFOLD; SUCCINIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL; BINDING SITE; CONTROLLED STUDY; ENZYME LOCALIZATION; ENZYME METABOLISM; ENZYME STRUCTURE; ENZYME SYNTHESIS; ESCHERICHIA COLI; FLUORESCENCE MICROSCOPY; IN VIVO STUDY; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN RNA BINDING;

ALKANES; APTAMERS, NUCLEOTIDE; ENZYMES; ESCHERICHIA COLI; FLUORESCENT DYES; GREEN FLUORESCENT PROTEINS; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RNA; RNA-BINDING PROTEINS; SUCCINIC ACID;

EID: 84906248340     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku617     Document Type: Article

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