Decoding transcriptional enhancers: Evolving from annotation to functional interpretation

Seminars in Cell and Developmental Biology

Volumn 57, Issue , 2016, Pages 40-50

  Engel, Krysta L ^a   Mackiewicz, Mark ^a   Hardigan, Andrew A ^a,b   Myers, Richard M ^a   Savic, Daniel ^a  

^a HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

CRISPR genome editing; Development; Disease; Enhancers; Functional genomics; Next generation sequencing; Transcription factors

Indexed keywords

RNA POLYMERASE II;

DISEASE COURSE; DNA SEQUENCE; ENHANCER REGION; FUNCTIONAL GENOMICS; GENE CONTROL; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; NONHUMAN; PHENOTYPE; REVIEW; ANIMAL; BIOLOGICAL MODEL; DISEASES; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MOLECULAR GENETICS;

ANIMALS; DISEASE; EMBRYONIC DEVELOPMENT; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE ANNOTATION;

EID: 84971644070     PISSN: 10849521     EISSN: 10963634     Source Type: Journal    
DOI: 10.1016/j.semcdb.2016.05.014     Document Type: Review

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