Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay

Genome Research

Volumn 23, Issue 5, 2013, Pages 800-811

  Kheradpour, Pouya ^a,b   Ernst, Jason ^a,b,e   Melnikov, Alexandre ^b   Rogov, Peter ^b   Wang, Li ^b   Zhang, Xiaolan ^b   Alston, Jessica ^b,c   Mikkelsen, Tarjei S ^b,d   Kellis, Manolis ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Harvard University   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; FORKHEAD TRANSCRIPTION FACTOR; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 4; NUCLEOTIDE; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR GATA;

ARTICLE; BIOASSAY; CELL STRAIN HEPG2; CHROMATIN; CONTROLLED STUDY; ENHANCER REGION; ERYTHROLEUKEMIA CELL; GENE ACTIVATION; GENE ACTIVITY; GENE DISRUPTION; GENE EXPRESSION; GENE REPRESSION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC ENGINEERING; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; NUCLEOSOME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; REGULATORY SEQUENCE; REPORTER GENE; WILD TYPE;

BASE SEQUENCE; BINDING SITES; CELLS; CHROMATIN; CHROMOSOME MAPPING; CONSERVED SEQUENCE; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; GENES, REPORTER; GENOME, HUMAN; HEP G2 CELLS; HUMANS; NUCLEOTIDE MOTIFS; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC;

EID: 84877147962     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.144899.112     Document Type: Article

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