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Volumn 64, Issue 6, 2016, Pages 463-483

Transcription Factor NF-κB: An Update on Intervention Strategies

Author keywords

Asthma; Cancer; COPD; DNA damage; HIV; HSV; NF B

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

EID: 84970973745     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-016-0405-y     Document Type: Review
Times cited : (102)

References (172)
  • 1
    • 84937765016 scopus 로고    scopus 로고
    • Vitamin D attenuates pro-inflammatory TNF-alpha cytokine expression by inhibiting NF-small ka, CyrillicB/p65 signaling in hypertrophied rat hearts
    • COI: 1:CAS:528:DC%2BC2MXot1elsbk%3D, PID: 25929726
    • Al-Rasheed NM, Al-Rasheed NM, Bassiouni YA et al (2015) Vitamin D attenuates pro-inflammatory TNF-alpha cytokine expression by inhibiting NF-small ka, CyrillicB/p65 signaling in hypertrophied rat hearts. J Physiol Biochem 71:289–299
    • (2015) J Physiol Biochem , vol.71 , pp. 289-299
    • Al-Rasheed, N.M.1    Al-Rasheed, N.M.2    Bassiouni, Y.A.3
  • 2
    • 84906256686 scopus 로고    scopus 로고
    • Heme oxygenase-1 dysregulation in the brain: implications for HIV-associated neurocognitive disorders
    • COI: 1:CAS:528:DC%2BC2cXhtlKgsr%2FO, PID: 24862327
    • Ambegaokar SS, Kolson DL (2014) Heme oxygenase-1 dysregulation in the brain: implications for HIV-associated neurocognitive disorders. Curr HIV Res 12:174
    • (2014) Curr HIV Res , vol.12 , pp. 174
    • Ambegaokar, S.S.1    Kolson, D.L.2
  • 3
    • 84898772703 scopus 로고    scopus 로고
    • Heat shock protein 90 controls HIV-1 reactivation from latency
    • COI: 1:CAS:528:DC%2BC2cXltl2ksLw%3D, PID: 24706778
    • Anderson I, Low JS, Weston S et al (2014) Heat shock protein 90 controls HIV-1 reactivation from latency. Proc Natl Acad Sci USA 111:E1528–E1537
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. E1528-E1537
    • Anderson, I.1    Low, J.S.2    Weston, S.3
  • 4
    • 77954297744 scopus 로고    scopus 로고
    • Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancer
    • COI: 1:CAS:528:DC%2BC3cXptlWqu7k%3D, PID: 20564628
    • Annunziata CM, Stavnes HT, Kleinberg L et al (2010) Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancer. Cancer 116:3276–3284
    • (2010) Cancer , vol.116 , pp. 3276-3284
    • Annunziata, C.M.1    Stavnes, H.T.2    Kleinberg, L.3
  • 5
    • 33751352908 scopus 로고    scopus 로고
    • Anti-tumour necrosis factor-alpha therapy in heart failure: future directions
    • COI: 1:CAS:528:DC%2BD2sXhs1Wjuw%3D%3D, PID: 17169118
    • Balakumar P, Singh M (2006) Anti-tumour necrosis factor-alpha therapy in heart failure: future directions. Basic Clin Pharmacol Toxicol 99:391–397
    • (2006) Basic Clin Pharmacol Toxicol , vol.99 , pp. 391-397
    • Balakumar, P.1    Singh, M.2
  • 6
    • 84891868645 scopus 로고    scopus 로고
    • Misfolded protein structure and proteostasis in lung diseases
    • PID: 24033344
    • Balch WE, Sznajder JI, Budinger S et al (2014) Misfolded protein structure and proteostasis in lung diseases. Am J Respir Crit Care Med 189:96–103
    • (2014) Am J Respir Crit Care Med , vol.189 , pp. 96-103
    • Balch, W.E.1    Sznajder, J.I.2    Budinger, S.3
  • 8
    • 84941028441 scopus 로고    scopus 로고
    • Therapeutic approaches to asthma-chronic obstructive pulmonary disease overlap syndromes
    • PID: 26343937
    • Barnes PJ (2015) Therapeutic approaches to asthma-chronic obstructive pulmonary disease overlap syndromes. J Allergy Clin Immunol 136:531–545
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 531-545
    • Barnes, P.J.1
  • 9
    • 0037962488 scopus 로고    scopus 로고
    • BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit
    • COI: 1:CAS:528:DC%2BD3sXltlKru74%3D, PID: 12700228
    • Benezra M, Chevallier N, Morrison DJ et al (2003) BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit. J Biol Chem 278:26333–26341
    • (2003) J Biol Chem , vol.278 , pp. 26333-26341
    • Benezra, M.1    Chevallier, N.2    Morrison, D.J.3
  • 10
    • 26944458839 scopus 로고    scopus 로고
    • Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma
    • PID: 16002568
    • Birrell MA, Hardaker E, Wong S et al (2005) Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma. Am J Respir Crit Care Med 172:962–971
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 962-971
    • Birrell, M.A.1    Hardaker, E.2    Wong, S.3
  • 11
    • 0034682527 scopus 로고    scopus 로고
    • Epidermal growth factor-induced nuclear factor κB activation: a major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells
    • COI: 1:CAS:528:DC%2BD3cXlt1Gnsrg%3D, PID: 10900013
    • Biswas DK, Cruz AP, Gansberger E et al (2000) Epidermal growth factor-induced nuclear factor κB activation: a major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proc Natl Acad Sci USA 97:8542–8547
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8542-8547
    • Biswas, D.K.1    Cruz, A.P.2    Gansberger, E.3
  • 12
    • 3042716638 scopus 로고    scopus 로고
    • NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis
    • COI: 1:CAS:528:DC%2BD2cXlvFOhsL4%3D, PID: 15220474
    • Biswas DK, Shi Q, Baily S et al (2004) NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis. Proc Natl Acad Sci USA 101:10137–10142
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10137-10142
    • Biswas, D.K.1    Shi, Q.2    Baily, S.3
  • 13
    • 0033053617 scopus 로고    scopus 로고
    • Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity
    • COI: 1:CAS:528:DyaK1MXhsFeqtbw%3D, PID: 10022882
    • Bonizzi G, Piette J, Schoonbroodt S et al (1999) Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity. Mol Cell Biol 19:1950–1960
    • (1999) Mol Cell Biol , vol.19 , pp. 1950-1960
    • Bonizzi, G.1    Piette, J.2    Schoonbroodt, S.3
  • 14
    • 13544268716 scopus 로고    scopus 로고
    • Herpes simplex virus infection of human dendritic cells induces apoptosis and allows cross-presentation via uninfected dendritic cells
    • COI: 1:CAS:528:DC%2BD2MXhtV2rtro%3D, PID: 15699155
    • Bosnjak L, Miranda-Saksena M, Koelle DM et al (2005) Herpes simplex virus infection of human dendritic cells induces apoptosis and allows cross-presentation via uninfected dendritic cells. J Immunol 174:2220–2227
    • (2005) J Immunol , vol.174 , pp. 2220-2227
    • Bosnjak, L.1    Miranda-Saksena, M.2    Koelle, D.M.3
  • 15
    • 0033668713 scopus 로고    scopus 로고
    • ICAM-1 deficiency reduces atherosclerotic lesions in double-knockout mice (ApoE(−/−)/ICAM-1(−/−)) fed a fat or a chow diet
    • COI: 1:CAS:528:DC%2BD3MXitlWitg%3D%3D, PID: 11116064
    • Bourdillon MC, Poston RN, Covacho C et al (2000) ICAM-1 deficiency reduces atherosclerotic lesions in double-knockout mice (ApoE(−/−)/ICAM-1(−/−)) fed a fat or a chow diet. Arterioscler Thromb Vasc Biol 20:2630–2635
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2630-2635
    • Bourdillon, M.C.1    Poston, R.N.2    Covacho, C.3
  • 16
    • 8344275053 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-alpha reduces atherosclerosis in apolipoprotein E knockout mice
    • COI: 1:CAS:528:DC%2BD2cXptV2isr4%3D, PID: 15345516
    • Branen L, Hovgaard L, Nitulescu M et al (2004) Inhibition of tumor necrosis factor-alpha reduces atherosclerosis in apolipoprotein E knockout mice. Arterioscler Thromb Vasc Biol 24:2137–2142
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2137-2142
    • Branen, L.1    Hovgaard, L.2    Nitulescu, M.3
  • 17
    • 0036089393 scopus 로고    scopus 로고
    • NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle
    • COI: 1:CAS:528:DC%2BD38XivVeltLo%3D, PID: 11880305
    • Brar SS, Kennedy TP, Sturrock AB et al (2002) NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 282:L782–L795
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282 , pp. L782-L795
    • Brar, S.S.1    Kennedy, T.P.2    Sturrock, A.B.3
  • 18
    • 84925883883 scopus 로고    scopus 로고
    • The role of tau protein in HIV-associated neurocognitive disorders
    • PID: 25304757
    • Brown LA, Scarola J, Smith AJ et al (2014) The role of tau protein in HIV-associated neurocognitive disorders. Mol Neurodegener 9:40
    • (2014) Mol Neurodegener , vol.9 , pp. 40
    • Brown, L.A.1    Scarola, J.2    Smith, A.J.3
  • 19
    • 84927639135 scopus 로고    scopus 로고
    • Innate immune pattern recognition: a cell biological perspective
    • COI: 1:CAS:528:DC%2BC2MXhsVSisL3O, PID: 25581309
    • Brubaker SW, Bonham KS, Zanoni I et al (2015) Innate immune pattern recognition: a cell biological perspective. Annu Rev Immunol 33:257–290
    • (2015) Annu Rev Immunol , vol.33 , pp. 257-290
    • Brubaker, S.W.1    Bonham, K.S.2    Zanoni, I.3
  • 20
    • 0026533363 scopus 로고
    • Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells
    • COI: 1:CAS:528:DyaK38XisFWqsLc%3D, PID: 1313909
    • Cai W, Schaffer PA (1992) Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells. J Virol 66:2904–2915
    • (1992) J Virol , vol.66 , pp. 2904-2915
    • Cai, W.1    Schaffer, P.A.2
  • 21
    • 84940663022 scopus 로고    scopus 로고
    • Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis
    • PID: 26324807
    • Cazzola M, Calzetta L, Page C et al (2015) Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis. Eur Respir Rev 24:451–461
    • (2015) Eur Respir Rev , vol.24 , pp. 451-461
    • Cazzola, M.1    Calzetta, L.2    Page, C.3
  • 22
    • 0344925521 scopus 로고    scopus 로고
    • Oxidative stress in cardiovascular disease: myth or fact?
    • COI: 1:CAS:528:DC%2BD3sXptl2qsLs%3D, PID: 14654060
    • Ceconi C, Boraso A, Cargnoni A et al (2003) Oxidative stress in cardiovascular disease: myth or fact? Arch Biochem Biophys 420:217–221
    • (2003) Arch Biochem Biophys , vol.420 , pp. 217-221
    • Ceconi, C.1    Boraso, A.2    Cargnoni, A.3
  • 23
    • 79955068704 scopus 로고    scopus 로고
    • NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target
    • COI: 1:CAS:528:DC%2BC3MXisVGnu7Y%3D
    • Chen W, Li Z, Bai L et al (2011) NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target. Front Biosci 16:1172–1185
    • (2011) Front Biosci , vol.16 , pp. 1172-1185
    • Chen, W.1    Li, Z.2    Bai, L.3
  • 24
    • 84887326965 scopus 로고    scopus 로고
    • Lapatinib–induced NF-kappaB activation sensitizes triple-negative breast cancer cells to proteasome inhibitors
    • PID: 24216290
    • Chen YJ, Yeh MH, Yu MC et al (2013) Lapatinib–induced NF-kappaB activation sensitizes triple-negative breast cancer cells to proteasome inhibitors. Breast Cancer Res 15:R108
    • (2013) Breast Cancer Res , vol.15 , pp. R108
    • Chen, Y.J.1    Yeh, M.H.2    Yu, M.C.3
  • 25
    • 84897862589 scopus 로고    scopus 로고
    • SIRT4 inhibits cigarette smoke extracts-induced mononuclear cell adhesion to human pulmonary microvascular endothelial cells via regulating NF-κB activity
    • COI: 1:CAS:528:DC%2BC2cXmsFCgu7w%3D, PID: 24603126
    • Chen Y, Wang H, Luo G et al (2014) SIRT4 inhibits cigarette smoke extracts-induced mononuclear cell adhesion to human pulmonary microvascular endothelial cells via regulating NF-κB activity. Toxicol Lett 226:320–327
    • (2014) Toxicol Lett , vol.226 , pp. 320-327
    • Chen, Y.1    Wang, H.2    Luo, G.3
  • 26
    • 84924279540 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioma cell invasion through induction of NF-κB-inducing kinase (NIK) and noncanonical NF-κB signaling
    • COI: 1:CAS:528:DC%2BC2MXkt1eisb0%3D, PID: 25622756
    • Cherry EM, Lee DW, Jung JU et al (2015) Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioma cell invasion through induction of NF-κB-inducing kinase (NIK) and noncanonical NF-κB signaling. Mol Cancer 14:9
    • (2015) Mol Cancer , vol.14 , pp. 9
    • Cherry, E.M.1    Lee, D.W.2    Jung, J.U.3
  • 27
    • 8344273480 scopus 로고    scopus 로고
    • Nuclear factor kappa B activation by NADPH oxidases
    • COI: 1:CAS:528:DC%2BD2cXpslGmsr8%3D, PID: 15541774
    • Clark RA, Valente AJ (2004) Nuclear factor kappa B activation by NADPH oxidases. Mech Ageing Dev 125:799–810
    • (2004) Mech Ageing Dev , vol.125 , pp. 799-810
    • Clark, R.A.1    Valente, A.J.2
  • 28
    • 0034708132 scopus 로고    scopus 로고
    • Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3
    • COI: 1:CAS:528:DC%2BD3cXitFeqt7c%3D, PID: 10713699
    • Cogswell PC, Guttridge DC, Funkhouser WK et al (2000) Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. Oncogene 19:1123–1131
    • (2000) Oncogene , vol.19 , pp. 1123-1131
    • Cogswell, P.C.1    Guttridge, D.C.2    Funkhouser, W.K.3
  • 29
    • 0034598336 scopus 로고    scopus 로고
    • P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice
    • COI: 1:CAS:528:DC%2BD3cXktFyrug%3D%3D, PID: 10620617
    • Collins RG, Velji R, Guevara NV et al (2000) P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice. J Exp Med 191:189–194
    • (2000) J Exp Med , vol.191 , pp. 189-194
    • Collins, R.G.1    Velji, R.2    Guevara, N.V.3
  • 30
    • 34248201283 scopus 로고    scopus 로고
    • A transgenic model reveals important roles for the NF-κB alternative pathway (p100/p52) in mammary development and links to tumorigenesis
    • COI: 1:CAS:528:DC%2BD2sXjtlCisLs%3D, PID: 17261585
    • Connelly L, Robinson-Benion C, Chont M et al (2007) A transgenic model reveals important roles for the NF-κB alternative pathway (p100/p52) in mammary development and links to tumorigenesis. J Biol Chem 282:10028–10035
    • (2007) J Biol Chem , vol.282 , pp. 10028-10035
    • Connelly, L.1    Robinson-Benion, C.2    Chont, M.3
  • 31
    • 0031037913 scopus 로고    scopus 로고
    • Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli
    • COI: 1:CAS:528:DyaK2sXhtlGnu78%3D, PID: 9032271
    • Courtois G, Whiteside ST, Sibley CH et al (1997) Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli. Mol Cell Biol 17:1441–1449
    • (1997) Mol Cell Biol , vol.17 , pp. 1441-1449
    • Courtois, G.1    Whiteside, S.T.2    Sibley, C.H.3
  • 32
    • 0021023416 scopus 로고
    • Determinants of ovarian cancer risk. II. Inferences regarding pathogenesis
    • COI: 1:STN:280:DyaL2c%2FhtFyisg%3D%3D, PID: 6578367
    • Cramer DW, Welch WR (1983) Determinants of ovarian cancer risk. II. Inferences regarding pathogenesis. J Natl Cancer Inst 71:717–721
    • (1983) J Natl Cancer Inst , vol.71 , pp. 717-721
    • Cramer, D.W.1    Welch, W.R.2
  • 33
    • 0035328584 scopus 로고    scopus 로고
    • Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition
    • COI: 1:CAS:528:DC%2BD3MXjsFCgt7o%3D, PID: 11325813
    • Cusack JC Jr, Liu R, Houston M et al (2001) Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition. Cancer Res 61:3535–3540
    • (2001) Cancer Res , vol.61 , pp. 3535-3540
    • Cusack, J.C.1    Liu, R.2    Houston, M.3
  • 34
    • 84921324809 scopus 로고    scopus 로고
    • Understanding HIV latency: the road to an HIV cure
    • COI: 1:CAS:528:DC%2BC2MXjvFyhsbo%3D, PID: 25587657
    • Dahabieh MS, Battivelli E, Verdin E (2015) Understanding HIV latency: the road to an HIV cure. Annu Rev Med 66:407–421
    • (2015) Annu Rev Med , vol.66 , pp. 407-421
    • Dahabieh, M.S.1    Battivelli, E.2    Verdin, E.3
  • 35
    • 84895801800 scopus 로고    scopus 로고
    • CCAAT enhancer binding protein and nuclear factor of activated T cells regulate HIV-1 LTR via a novel conserved downstream site in cells of the monocyte-macrophage lineage
    • PID: 24551078
    • Dahiya S, Liu Y, Nonnemacher MR et al (2014a) CCAAT enhancer binding protein and nuclear factor of activated T cells regulate HIV-1 LTR via a novel conserved downstream site in cells of the monocyte-macrophage lineage. PLoS One 9:e88116
    • (2014) PLoS One , vol.9
    • Dahiya, S.1    Liu, Y.2    Nonnemacher, M.R.3
  • 36
    • 84992684798 scopus 로고    scopus 로고
    • Role of downstream elements in transcriptional regulation of the HIV-1 promoter
    • Dahiya S, Liu Y, Williams J et al (2014b) Role of downstream elements in transcriptional regulation of the HIV-1 promoter. J Hum Virol Retrovirol 1:00006
    • (2014) J Hum Virol Retrovirol , vol.1 , pp. 00006
    • Dahiya, S.1    Liu, Y.2    Williams, J.3
  • 38
    • 0028866540 scopus 로고
    • Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells
    • COI: 1:CAS:528:DyaK2MXptlOks7o%3D, PID: 7478612
    • Dejardin E, Bonizzi G, Bellahcene A et al (1995) Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells. Oncogene 11:1835–1841
    • (1995) Oncogene , vol.11 , pp. 1835-1841
    • Dejardin, E.1    Bonizzi, G.2    Bellahcene, A.3
  • 39
    • 0033527569 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
    • COI: 1:CAS:528:DyaK1MXnt12jt74%3D, PID: 10542237
    • Delerive P, De Bosscher K, Besnard S et al (1999) Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem 274:32048–32054
    • (1999) J Biol Chem , vol.274 , pp. 32048-32054
    • Delerive, P.1    De Bosscher, K.2    Besnard, S.3
  • 40
    • 8644282751 scopus 로고    scopus 로고
    • Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
    • COI: 1:CAS:528:DC%2BD2cXhtVart7zJ, PID: 15542827
    • Deng J, Lu PD, Zhang Y et al (2004) Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol 24:10161–10168
    • (2004) Mol Cell Biol , vol.24 , pp. 10161-10168
    • Deng, J.1    Lu, P.D.2    Zhang, Y.3
  • 41
    • 0034083227 scopus 로고    scopus 로고
    • Role of oxidative stress in cardiovascular diseases
    • COI: 1:CAS:528:DC%2BD3cXksFWrur4%3D, PID: 10872549
    • Dhalla NS, Temsah RM, Netticadan T (2000) Role of oxidative stress in cardiovascular diseases. J Hypertens 18:655–673
    • (2000) J Hypertens , vol.18 , pp. 655-673
    • Dhalla, N.S.1    Temsah, R.M.2    Netticadan, T.3
  • 42
    • 67650653218 scopus 로고    scopus 로고
    • T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients
    • PID: 19604272
    • Di Stefano A, Caramori G, Gnemmi I et al (2009) T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin Exp Immunol 157:316–324
    • (2009) Clin Exp Immunol , vol.157 , pp. 316-324
    • Di Stefano, A.1    Caramori, G.2    Gnemmi, I.3
  • 43
    • 84876792771 scopus 로고    scopus 로고
    • Prospective memory in HIV-associated neurocognitive disorders (HAND): the neuropsychological dynamics of time monitoring
    • PID: 23465043
    • Doyle KL, Loft S, Morgan EE et al (2013) Prospective memory in HIV-associated neurocognitive disorders (HAND): the neuropsychological dynamics of time monitoring. J Clin Exp Neuropsychol 35:359–372
    • (2013) J Clin Exp Neuropsychol , vol.35 , pp. 359-372
    • Doyle, K.L.1    Loft, S.2    Morgan, E.E.3
  • 44
    • 57749105255 scopus 로고    scopus 로고
    • Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease
    • COI: 1:CAS:528:DC%2BD1cXhsFagtr3E, PID: 18950657
    • Edwards MR, Bartlett NW, Clarke D et al (2009) Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease. Pharmacol Ther 121:1–13
    • (2009) Pharmacol Ther , vol.121 , pp. 1-13
    • Edwards, M.R.1    Bartlett, N.W.2    Clarke, D.3
  • 45
    • 84883481856 scopus 로고    scopus 로고
    • Immunological control of herpes simplex virus infections
    • COI: 1:CAS:528:DC%2BC3sXhsVSisb%2FE, PID: 23943467
    • Egan KP, Wu S, Wigdahl B et al (2013) Immunological control of herpes simplex virus infections. J Neurovirol 19:328–345
    • (2013) J Neurovirol , vol.19 , pp. 328-345
    • Egan, K.P.1    Wu, S.2    Wigdahl, B.3
  • 46
    • 84887332032 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 viral protein R (Vpr) induces CCL5 expression in astrocytes via PI3 K and MAPK signaling pathways
    • PID: 24225433
    • Gangwani MR, Noel RJ Jr, Shah A et al (2013) Human immunodeficiency virus type 1 viral protein R (Vpr) induces CCL5 expression in astrocytes via PI3 K and MAPK signaling pathways. J Neuroinflammation 10:136
    • (2013) J Neuroinflammation , vol.10 , pp. 136
    • Gangwani, M.R.1    Noel, R.J.2    Shah, A.3
  • 47
    • 33750466230 scopus 로고    scopus 로고
    • Introduction to NF-kappaB: players, pathways, perspectives
    • COI: 1:CAS:528:DC%2BD28XhtFektL7E, PID: 17072321
    • Gilmore TD (2006) Introduction to NF-kappaB: players, pathways, perspectives. Oncogene 25:6680–6684
    • (2006) Oncogene , vol.25 , pp. 6680-6684
    • Gilmore, T.D.1
  • 48
    • 84920609122 scopus 로고    scopus 로고
    • CXCL8 (interleukin 8)—the key inflammatory mediator in chronic obstructive pulmonary disease?
    • Gilowska I (2014) CXCL8 (interleukin 8)—the key inflammatory mediator in chronic obstructive pulmonary disease? Postepy Hig Med Dosw (Online) 68:842–850
    • (2014) Postepy Hig Med Dosw (Online) , vol.68 , pp. 842-850
    • Gilowska, I.1
  • 49
    • 0038678185 scopus 로고    scopus 로고
    • NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infection
    • COI: 1:CAS:528:DC%2BD3sXkvV2qtb8%3D, PID: 12805425
    • Goodkin ML, Ting AT, Blaho JA (2003) NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infection. J Virol 77:7261–7280
    • (2003) J Virol , vol.77 , pp. 7261-7280
    • Goodkin, M.L.1    Ting, A.T.2    Blaho, J.A.3
  • 50
    • 0032944799 scopus 로고    scopus 로고
    • Possible role of NF-kappaB and p53 in the glutamate-induced pro-apoptotic neuronal pathway
    • COI: 1:CAS:528:DyaK1MXhsF2rsbw%3D, PID: 10200544
    • Grilli M, Memo M (1999) Possible role of NF-kappaB and p53 in the glutamate-induced pro-apoptotic neuronal pathway. Cell Death Differ 6:22–27
    • (1999) Cell Death Differ , vol.6 , pp. 22-27
    • Grilli, M.1    Memo, M.2
  • 51
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • COI: 1:CAS:528:DC%2BC3cXlsVSgu7g%3D, PID: 20303878
    • Grivennikov SI, Greten FR, Karin M (2010) Immunity, inflammation, and cancer. Cell 140:883–899
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 52
    • 84885666003 scopus 로고    scopus 로고
    • mTOR regulates DNA damage response through NF-kappaB-mediated FANCD2 pathway in hematopoietic cells
    • COI: 1:CAS:528:DC%2BC3sXhsF2gtb3E, PID: 23538752
    • Guo F, Li J, Du W et al (2013) mTOR regulates DNA damage response through NF-kappaB-mediated FANCD2 pathway in hematopoietic cells. Leukemia 27:2040–2046
    • (2013) Leukemia , vol.27 , pp. 2040-2046
    • Guo, F.1    Li, J.2    Du, W.3
  • 53
    • 84905376910 scopus 로고    scopus 로고
    • HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes
    • PID: 24939850
    • Guo H, Gao J, Taxman DJ et al (2014) HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes. J Biol Chem 289:21716–21726
    • (2014) J Biol Chem , vol.289 , pp. 21716-21726
    • Guo, H.1    Gao, J.2    Taxman, D.J.3
  • 54
    • 84904282236 scopus 로고    scopus 로고
    • Ligand-binding pocket bridges DNA-binding and dimerization domains of the urate-responsive MarR homologue MftR from Burkholderia thailandensis
    • COI: 1:CAS:528:DC%2BC2cXhtVajs7%2FF, PID: 24955985
    • Gupta A, Grove A (2014) Ligand-binding pocket bridges DNA-binding and dimerization domains of the urate-responsive MarR homologue MftR from Burkholderia thailandensis. Biochemistry 53:4368–4380
    • (2014) Biochemistry , vol.53 , pp. 4368-4380
    • Gupta, A.1    Grove, A.2
  • 55
    • 3042535469 scopus 로고    scopus 로고
    • A case of advanced pancreatic cancer with remarkable response to thalidomide, celecoxib and gemcitabine
    • Hada M, Mizutari K (2004) A case of advanced pancreatic cancer with remarkable response to thalidomide, celecoxib and gemcitabine. Cancer Chemother 31:959–961
    • (2004) Cancer Chemother , vol.31 , pp. 959-961
    • Hada, M.1    Mizutari, K.2
  • 56
    • 84928812228 scopus 로고    scopus 로고
    • Heparanase is a host enzyme required for herpes simplex virus-1 release from cells
    • COI: 1:CAS:528:DC%2BC2MXosFels7Y%3D, PID: 25912399
    • Hadigal SR, Agelidis AM, Karasneh GA et al (2015) Heparanase is a host enzyme required for herpes simplex virus-1 release from cells. Nat Commun 6:6985
    • (2015) Nat Commun , vol.6 , pp. 6985
    • Hadigal, S.R.1    Agelidis, A.M.2    Karasneh, G.A.3
  • 57
    • 33750285635 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 ICP27-dependent activation of NF-kappaB
    • COI: 1:CAS:528:DC%2BD28XhtFygsLfI, PID: 16928747
    • Hargett D, Rice S, Bachenheimer SL (2006) Herpes simplex virus type 1 ICP27-dependent activation of NF-kappaB. J Virol 80:10565–10578
    • (2006) J Virol , vol.80 , pp. 10565-10578
    • Hargett, D.1    Rice, S.2    Bachenheimer, S.L.3
  • 58
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • COI: 1:CAS:528:DC%2BD2cXnslCntbY%3D, PID: 15371334
    • Hayden MS, Ghosh S (2004) Signaling to NF-kappaB. Genes Dev 18:2195–2224
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 59
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • COI: 1:CAS:528:DC%2BD1cXivVahtbY%3D, PID: 18267068
    • Hayden MS, Ghosh S (2008) Shared principles in NF-kappaB signaling. Cell 132:344–362
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 60
    • 79952921819 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors
    • COI: 1:CAS:528:DC%2BC3MXisVyrtb8%3D, PID: 21174240
    • Heaton RK, Franklin DR, Ellis RJ et al (2011) HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol 17:3–16
    • (2011) J Neurovirol , vol.17 , pp. 3-16
    • Heaton, R.K.1    Franklin, D.R.2    Ellis, R.J.3
  • 61
    • 0033635935 scopus 로고    scopus 로고
    • Gemcitabine and cisplatin in the treatment of advanced or metastatic pancreatic cancer
    • COI: 1:STN:280:DC%2BD3M7lt12rtw%3D%3D, PID: 11142479
    • Heinemann V, Wilke H, Mergenthaler HG et al (2000) Gemcitabine and cisplatin in the treatment of advanced or metastatic pancreatic cancer. Ann Oncol 11:1399–1403
    • (2000) Ann Oncol , vol.11 , pp. 1399-1403
    • Heinemann, V.1    Wilke, H.2    Mergenthaler, H.G.3
  • 62
    • 33745830901 scopus 로고    scopus 로고
    • NF-kappaB signaling blockade by Bay 11-7085 during early cardiac morphogenesis induces alterations of the outflow tract in chicken heart
    • COI: 1:CAS:528:DC%2BD28Xmslantr8%3D, PID: 16699956
    • Hernandez-Gutierrez S, Garcia-Pelaez I, Zentella-Dehesa A et al (2006) NF-kappaB signaling blockade by Bay 11-7085 during early cardiac morphogenesis induces alterations of the outflow tract in chicken heart. Apoptosis 11:1101–1109
    • (2006) Apoptosis , vol.11 , pp. 1101-1109
    • Hernandez-Gutierrez, S.1    Garcia-Pelaez, I.2    Zentella-Dehesa, A.3
  • 63
    • 33645312379 scopus 로고    scopus 로고
    • Circuitry of nuclear factor kappaB signaling
    • PID: 16623771
    • Hoffmann A, Baltimore D (2006) Circuitry of nuclear factor kappaB signaling. Immunol Rev 210:171–186
    • (2006) Immunol Rev , vol.210 , pp. 171-186
    • Hoffmann, A.1    Baltimore, D.2
  • 64
    • 0017045374 scopus 로고
    • Role of hypertension in atherosclerosis and cardiovascular disease
    • COI: 1:CAS:528:DyaE2sXktFWisQ%3D%3D, PID: 136891
    • Hollander W (1976) Role of hypertension in atherosclerosis and cardiovascular disease. Am J Cardiol 38:786–800
    • (1976) Am J Cardiol , vol.38 , pp. 786-800
    • Hollander, W.1
  • 65
    • 84922309687 scopus 로고    scopus 로고
    • Houttuynia cordata targets the beginning stage of herpes simplex virus infection
    • PID: 25643242
    • Hung PY, Ho BC, Lee SY et al (2015) Houttuynia cordata targets the beginning stage of herpes simplex virus infection. PLoS One 10:e0115475
    • (2015) PLoS One , vol.10
    • Hung, P.Y.1    Ho, B.C.2    Lee, S.Y.3
  • 66
    • 77649271479 scopus 로고    scopus 로고
    • Extracellular matrix remodeling during the progression of volume overload-induced heart failure
    • COI: 1:CAS:528:DC%2BC3cXitVeisr0%3D, PID: 19524591
    • Hutchinson KR, Stewart JA Jr, Lucchesi PA (2010) Extracellular matrix remodeling during the progression of volume overload-induced heart failure. J Mol Cell Cardiol 48:564–569
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 564-569
    • Hutchinson, K.R.1    Stewart, J.A.2    Lucchesi, P.A.3
  • 67
    • 77957252647 scopus 로고    scopus 로고
    • The IKK complex, a central regulator of NF-kappaB activation
    • PID: 20300203
    • Israel A (2010) The IKK complex, a central regulator of NF-kappaB activation. Cold Spring Harb Perspect Biol 2:a000158
    • (2010) Cold Spring Harb Perspect Biol , vol.2 , pp. a000158
    • Israel, A.1
  • 68
    • 31344446119 scopus 로고    scopus 로고
    • Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
    • COI: 1:CAS:528:DC%2BD28XhtVyrtbc%3D, PID: 16380507
    • Ito K, Yamamura S, Essilfie-Quaye S et al (2006) Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med 203:7–13
    • (2006) J Exp Med , vol.203 , pp. 7-13
    • Ito, K.1    Yamamura, S.2    Essilfie-Quaye, S.3
  • 69
    • 84937130323 scopus 로고    scopus 로고
    • Role, function and therapeutic potential of microRNAs in vascular aging
    • COI: 1:CAS:528:DC%2BC2MXhtFKrsbjP, PID: 23941642
    • Jansen F, Yang X, Nickenig G et al (2015) Role, function and therapeutic potential of microRNAs in vascular aging. Curr Vasc Pharmacol 13:324–330
    • (2015) Curr Vasc Pharmacol , vol.13 , pp. 324-330
    • Jansen, F.1    Yang, X.2    Nickenig, G.3
  • 70
    • 67049158001 scopus 로고    scopus 로고
    • Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control
    • COI: 1:CAS:528:DC%2BD1MXmtFeiu7s%3D, PID: 19387025
    • Janssen-Heininger YM, Poynter ME, Aesif SW et al (2009) Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control. Proc Am Thorac Soc 6:249–255
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 249-255
    • Janssen-Heininger, Y.M.1    Poynter, M.E.2    Aesif, S.W.3
  • 71
    • 33646006734 scopus 로고    scopus 로고
    • Signals from within: the DNA-damage-induced NF-kappaB response
    • COI: 1:CAS:528:DC%2BD28XjsFWisbw%3D, PID: 16410802
    • Janssens S, Tschopp J (2006) Signals from within: the DNA-damage-induced NF-kappaB response. Cell Death Differ 13:773–784
    • (2006) Cell Death Differ , vol.13 , pp. 773-784
    • Janssens, S.1    Tschopp, J.2
  • 72
  • 73
    • 33846237270 scopus 로고    scopus 로고
    • Assessment of celecoxib pharmacodynamics in pancreatic cancer
    • COI: 1:CAS:528:DC%2BD28XhtlagsbjO, PID: 17172427
    • Jimeno A, Amador ML, Kulesza P et al (2006) Assessment of celecoxib pharmacodynamics in pancreatic cancer. Mol Cancer Ther 5:3240–3247
    • (2006) Mol Cancer Ther , vol.5 , pp. 3240-3247
    • Jimeno, A.1    Amador, M.L.2    Kulesza, P.3
  • 74
    • 0034744949 scopus 로고    scopus 로고
    • NF-kappaB and cell-cycle regulation: the cyclin connection
    • COI: 1:CAS:528:DC%2BD3MXjtFOhsbc%3D, PID: 11312120
    • Joyce D, Albanese C, Steer J et al (2001) NF-kappaB and cell-cycle regulation: the cyclin connection. Cytokine Growth Factor Rev 12:73–90
    • (2001) Cytokine Growth Factor Rev , vol.12 , pp. 73-90
    • Joyce, D.1    Albanese, C.2    Steer, J.3
  • 75
    • 84918811753 scopus 로고    scopus 로고
    • S100A8, S100A9 and S100A12 activate airway epithelial cells to produce MUC5AC via extracellular signal-regulated kinase and nuclear factor-κB pathways
    • COI: 1:CAS:528:DC%2BC2cXitVegurrI, PID: 24975020
    • Kang JH, Hwang SM, Chung IY (2015) S100A8, S100A9 and S100A12 activate airway epithelial cells to produce MUC5AC via extracellular signal-regulated kinase and nuclear factor-κB pathways. Immunology 144:79–90
    • (2015) Immunology , vol.144 , pp. 79-90
    • Kang, J.H.1    Hwang, S.M.2    Chung, I.Y.3
  • 76
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • COI: 1:CAS:528:DC%2BD28XkvVyrsrw%3D, PID: 16724054
    • Karin M (2006) Nuclear factor-kappaB in cancer development and progression. Nature 441:431–436
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 77
    • 77953859606 scopus 로고    scopus 로고
    • NF-kappaB as a critical link between inflammation and cancer
    • PID: 20066113
    • Karin M (2009) NF-kappaB as a critical link between inflammation and cancer. Cold Spring Harb Perspect Biol 1:a000141
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , pp. a000141
    • Karin, M.1
  • 78
    • 84863999140 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional regulation of HIV-1 gene expression
    • PID: 22355797
    • Karn J, Stoltzfus CM (2012) Transcriptional and posttranscriptional regulation of HIV-1 gene expression. Cold Spring Harb Perspect Med 2:a006916
    • (2012) Cold Spring Harb Perspect Med , vol.2 , pp. a006916
    • Karn, J.1    Stoltzfus, C.M.2
  • 79
    • 0034788136 scopus 로고    scopus 로고
    • Cytokines and HIV-1: interactions and clinical implications
    • COI: 1:CAS:528:DC%2BD3MXns1Wmsrc%3D, PID: 12959322
    • Kedzierska K, Crowe SM (2001) Cytokines and HIV-1: interactions and clinical implications. Antivir Chem Chemother 12:133–150
    • (2001) Antivir Chem Chemother , vol.12 , pp. 133-150
    • Kedzierska, K.1    Crowe, S.M.2
  • 80
    • 0034746510 scopus 로고    scopus 로고
    • Blockade NF-kappaB activation prohibits TNF-alpha-induced cyclooxygenase-2 gene expression in ED27 trophoblast-like cells
    • COI: 1:CAS:528:DC%2BD3MXhtlaksb8%3D, PID: 11162356
    • Kniss DA, Rovin B, Fertel RH et al (2001) Blockade NF-kappaB activation prohibits TNF-alpha-induced cyclooxygenase-2 gene expression in ED27 trophoblast-like cells. Placenta 22:80–89
    • (2001) Placenta , vol.22 , pp. 80-89
    • Kniss, D.A.1    Rovin, B.2    Fertel, R.H.3
  • 81
    • 84872300994 scopus 로고    scopus 로고
    • A novel cinnamate derivative attenuates asthma features and reduces bronchial epithelial injury in mouse model
    • COI: 1:CAS:528:DC%2BC3sXos1Wjsg%3D%3D, PID: 23137769
    • Kumar S, Mabalirajan U, Rehman R et al (2013) A novel cinnamate derivative attenuates asthma features and reduces bronchial epithelial injury in mouse model. Int Immunopharmacol 15:150–159
    • (2013) Int Immunopharmacol , vol.15 , pp. 150-159
    • Kumar, S.1    Mabalirajan, U.2    Rehman, R.3
  • 82
    • 84861062943 scopus 로고    scopus 로고
    • Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
    • COI: 1:CAS:528:DC%2BC38XmvVKmtrY%3D, PID: 22581922
    • Lassegue B, San Martin A, Griendling KK (2012) Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res 110:1364–1390
    • (2012) Circ Res , vol.110 , pp. 1364-1390
    • Lassegue, B.1    San Martin, A.2    Griendling, K.K.3
  • 83
    • 33846813656 scopus 로고    scopus 로고
    • Expression profiling identifies microRNA signature in pancreatic cancer
    • COI: 1:CAS:528:DC%2BD2sXhsVWhsrc%3D, PID: 17149698
    • Lee EJ, Gusev Y, Jiang J et al (2007) Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer 120:1046–1054
    • (2007) Int J Cancer , vol.120 , pp. 1046-1054
    • Lee, E.J.1    Gusev, Y.2    Jiang, J.3
  • 84
    • 34147165459 scopus 로고    scopus 로고
    • Essential role for caspase-8 in Toll-like receptors and NFkappaB signaling
    • COI: 1:CAS:528:DC%2BD2sXitlSrt78%3D, PID: 17213198
    • Lemmers B, Salmena L, Bidere N et al (2007) Essential role for caspase-8 in Toll-like receptors and NFkappaB signaling. J Biol Chem 282:7416–7423
    • (2007) J Biol Chem , vol.282 , pp. 7416-7423
    • Lemmers, B.1    Salmena, L.2    Bidere, N.3
  • 85
    • 84864010826 scopus 로고    scopus 로고
    • Herpes simplex virus glycoproteins gH/gL and gB bind Toll-like receptor 2, and soluble gH/gL is sufficient to activate NF-κB
    • COI: 1:CAS:528:DC%2BC38XosFegurk%3D, PID: 22496225
    • Leoni V, Gianni T, Salvioli S et al (2012) Herpes simplex virus glycoproteins gH/gL and gB bind Toll-like receptor 2, and soluble gH/gL is sufficient to activate NF-κB. J Virol 86:6555–6562
    • (2012) J Virol , vol.86 , pp. 6555-6562
    • Leoni, V.1    Gianni, T.2    Salvioli, S.3
  • 86
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • COI: 1:CAS:528:DC%2BD38XnsVGqsbg%3D, PID: 12360211
    • Li Q, Verma IM (2002) NF-kappaB regulation in the immune system. Nat Rev Immunol 2:725–734
    • (2002) Nat Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 87
    • 84929619735 scopus 로고    scopus 로고
    • Anti-inflammatory functions of Thunb. and its compounds: a perspective on its potential role in rheumatoid arthritis
    • PID: 26170903
    • Li J, Zhao F (2015) Anti-inflammatory functions of Thunb. and its compounds: a perspective on its potential role in rheumatoid arthritis. Exp Ther Med 10:3–6
    • (2015) Exp Ther Med , vol.10 , pp. 3-6
    • Li, J.1    Zhao, F.2
  • 88
    • 0033749383 scopus 로고    scopus 로고
    • Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy
    • COI: 1:CAS:528:DC%2BD3cXotFyntL4%3D, PID: 11070088
    • Li YY, Feng YQ, Kadokami T et al (2000) Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy. Proc Natl Acad Sci USA 97:12746–12751
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12746-12751
    • Li, Y.Y.1    Feng, Y.Q.2    Kadokami, T.3
  • 89
    • 1642588228 scopus 로고    scopus 로고
    • Pancreatic cancer
    • COI: 1:CAS:528:DC%2BD2cXisFOmsLY%3D, PID: 15051286
    • Li D, Xie K, Wolff R et al (2004) Pancreatic cancer. Lancet 363:1049–1057
    • (2004) Lancet , vol.363 , pp. 1049-1057
    • Li, D.1    Xie, K.2    Wolff, R.3
  • 90
    • 70350786933 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB expression and allergen-induced airway inflammation in a mouse allergic asthma model by andrographolide
    • COI: 1:CAS:528:DC%2BD1MXhsF2itr7E, PID: 19887051
    • Li J, Luo L, Wang X et al (2009) Inhibition of NF-kappaB expression and allergen-induced airway inflammation in a mouse allergic asthma model by andrographolide. Cell Mol Immunol 6:381–385
    • (2009) Cell Mol Immunol , vol.6 , pp. 381-385
    • Li, J.1    Luo, L.2    Wang, X.3
  • 91
    • 84894260421 scopus 로고    scopus 로고
    • TLR4-MyD88/Mal-NF-κB axis is involved in infection of HSV-2 in human cervical epithelial cells
    • PID: 24278275
    • Liu H, Chen K, Feng W et al (2013) TLR4-MyD88/Mal-NF-κB axis is involved in infection of HSV-2 in human cervical epithelial cells. PLoS One 8:e80327
    • (2013) PLoS One , vol.8
    • Liu, H.1    Chen, K.2    Feng, W.3
  • 92
    • 77953117152 scopus 로고    scopus 로고
    • Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer
    • COI: 1:STN:280:DC%2BC3crjtlWrug%3D%3D, PID: 20567622
    • Lo M, Ling V, Low C et al (2010) Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer. Curr Oncol 17:9
    • (2010) Curr Oncol , vol.17 , pp. 9
    • Lo, M.1    Ling, V.2    Low, C.3
  • 93
    • 80755143456 scopus 로고    scopus 로고
    • Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial
    • COI: 1:CAS:528:DC%2BC3MXhs1CisLzN, PID: 21969502
    • Loehrer PJ, Feng Y, Cardenes H et al (2011) Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial. J Clin Oncol 29:4105–4112
    • (2011) J Clin Oncol , vol.29 , pp. 4105-4112
    • Loehrer, P.J.1    Feng, Y.2    Cardenes, H.3
  • 94
    • 78650858038 scopus 로고    scopus 로고
    • miR-301a as an NF-kappaB activator in pancreatic cancer cells
    • COI: 1:CAS:528:DC%2BC3cXhsVOrsbzJ, PID: 21113131
    • Lu Z, Li Y, Takwi A et al (2011) miR-301a as an NF-kappaB activator in pancreatic cancer cells. EMBO J 30:57–67
    • (2011) EMBO J , vol.30 , pp. 57-67
    • Lu, Z.1    Li, Y.2    Takwi, A.3
  • 95
    • 84926482662 scopus 로고    scopus 로고
    • Astragaloside IV attenuates injury caused by myocardial ischemia/reperfusion in rats via regulation of toll-like receptor 4/nuclear factor-kappaB signaling pathway
    • COI: 1:CAS:528:DC%2BC2MXlvV2gt7c%3D, PID: 25604645
    • Lu M, Tang F, Zhang J et al (2015) Astragaloside IV attenuates injury caused by myocardial ischemia/reperfusion in rats via regulation of toll-like receptor 4/nuclear factor-kappaB signaling pathway. Phytother Res 29:599–606
    • (2015) Phytother Res , vol.29 , pp. 599-606
    • Lu, M.1    Tang, F.2    Zhang, J.3
  • 96
    • 4544224979 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression
    • COI: 1:CAS:528:DC%2BD2cXot1KisL8%3D, PID: 15380520
    • Luo JL, Maeda S, Hsu LC et al (2004) Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression. Cancer Cell 6:297–305
    • (2004) Cancer Cell , vol.6 , pp. 297-305
    • Luo, J.L.1    Maeda, S.2    Hsu, L.C.3
  • 97
    • 79958225650 scopus 로고    scopus 로고
    • MicroRNAs in NF-kappaB signaling
    • COI: 1:CAS:528:DC%2BC3MXnvFeltrc%3D, PID: 21502305
    • Ma X, Becker Buscaglia LE, Barker JR et al (2011) MicroRNAs in NF-kappaB signaling. J Mol Cell Biol 3:159–166
    • (2011) J Mol Cell Biol , vol.3 , pp. 159-166
    • Ma, X.1    Becker Buscaglia, L.E.2    Barker, J.R.3
  • 98
    • 33748188499 scopus 로고    scopus 로고
    • PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress
    • COI: 1:CAS:528:DC%2BD28XovFykt7g%3D, PID: 16906147
    • Mabb AM, Wuerzberger-Davis SM, Miyamoto S (2006) PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress. Nat Cell Biol 8:986–993
    • (2006) Nat Cell Biol , vol.8 , pp. 986-993
    • Mabb, A.M.1    Wuerzberger-Davis, S.M.2    Miyamoto, S.3
  • 100
    • 84857553880 scopus 로고    scopus 로고
    • Macrolide therapy for the prevention of acute exacerbations in chronic obstructive pulmonary disease
    • COI: 1:CAS:528:DC%2BC38XhtFGltLfP, PID: 22353707
    • Mammen MJ, Sethi S (2012) Macrolide therapy for the prevention of acute exacerbations in chronic obstructive pulmonary disease. Pol Arch Med Wewn 122:54–59
    • (2012) Pol Arch Med Wewn , vol.122 , pp. 54-59
    • Mammen, M.J.1    Sethi, S.2
  • 101
    • 70350501512 scopus 로고    scopus 로고
    • Ovarian cancer in endometriosis: molecular biology, pathology, and clinical management
    • PID: 19856044
    • Mandai M, Yamaguchi K, Matsumura N et al (2009) Ovarian cancer in endometriosis: molecular biology, pathology, and clinical management. Int J Clin Oncol 14:383–391
    • (2009) Int J Clin Oncol , vol.14 , pp. 383-391
    • Mandai, M.1    Yamaguchi, K.2    Matsumura, N.3
  • 102
    • 0036843272 scopus 로고    scopus 로고
    • Synergistic inhibition of herpesvirus replication by docosanol and antiviral nucleoside analogs
    • COI: 1:CAS:528:DC%2BD38XnsVaisrc%3D, PID: 12367721
    • Marcelletti JF (2002) Synergistic inhibition of herpesvirus replication by docosanol and antiviral nucleoside analogs. Antiviral Res 56:153–166
    • (2002) Antiviral Res , vol.56 , pp. 153-166
    • Marcelletti, J.F.1
  • 103
    • 77952902769 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disorders: is there a hidden epidemic?
    • PID: 20559041
    • McArthur JC, Brew BJ (2010) HIV-associated neurocognitive disorders: is there a hidden epidemic? AIDS 24:1367–1370
    • (2010) AIDS , vol.24 , pp. 1367-1370
    • McArthur, J.C.1    Brew, B.J.2
  • 104
    • 84858722471 scopus 로고    scopus 로고
    • DNA damage-dependent NF-kappaB activation: NEMO turns nuclear signaling inside out
    • PID: 22435563
    • McCool KW, Miyamoto S (2012) DNA damage-dependent NF-kappaB activation: NEMO turns nuclear signaling inside out. Immunol Rev 246:311–326
    • (2012) Immunol Rev , vol.246 , pp. 311-326
    • McCool, K.W.1    Miyamoto, S.2
  • 105
    • 84881004053 scopus 로고    scopus 로고
    • Expression and significance of Toll-like receptor-4 in rats lung established by passive smoking or associated with intratracheal instillation of lipopolysaccharide
    • COI: 1:CAS:528:DC%2BC3sXhslyisbbM, PID: 24169336
    • Meng Y, Yu CH, Li T et al (2013) Expression and significance of Toll-like receptor-4 in rats lung established by passive smoking or associated with intratracheal instillation of lipopolysaccharide. Zhonghua Yi Xue Za Zhi 93:2230–2234
    • (2013) Zhonghua Yi Xue Za Zhi , vol.93 , pp. 2230-2234
    • Meng, Y.1    Yu, C.H.2    Li, T.3
  • 106
    • 79960013933 scopus 로고    scopus 로고
    • Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysema
    • COI: 1:CAS:528:DC%2BC3MXmtl2ltr4%3D, PID: 21318260
    • Min T, Bodas M, Mazur S et al (2011) Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysema. J Mol Med 89:577–593
    • (2011) J Mol Med , vol.89 , pp. 577-593
    • Min, T.1    Bodas, M.2    Mazur, S.3
  • 107
    • 33748744702 scopus 로고    scopus 로고
    • Antitumor effects of the proteasome inhibitor bortezomib in medullary and anaplastic thyroid carcinoma cells in vitro
    • COI: 1:CAS:528:DC%2BD28XhtFSjtb3O, PID: 16849420
    • Mitsiades CS, McMillin D, Kotoula V et al (2006) Antitumor effects of the proteasome inhibitor bortezomib in medullary and anaplastic thyroid carcinoma cells in vitro. J Clin Endocrinol Metab 91:4013–4021
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4013-4021
    • Mitsiades, C.S.1    McMillin, D.2    Kotoula, V.3
  • 108
    • 0035098881 scopus 로고    scopus 로고
    • Molecular pathways in virus-induced cytokine production
    • COI: 1:CAS:528:DC%2BD3MXisFyms7s%3D, PID: 11238989
    • Mogensen TH, Paludan SR (2001) Molecular pathways in virus-induced cytokine production. Microbiol Mol Biol Rev 65:131–150
    • (2001) Microbiol Mol Biol Rev , vol.65 , pp. 131-150
    • Mogensen, T.H.1    Paludan, S.R.2
  • 109
    • 77249153089 scopus 로고    scopus 로고
    • Proteasomal inhibition upregulates the endogenous MAPK deactivator MKP-1 in human airway smooth muscle: mechanism of action and effect on cytokine secretion
    • COI: 1:CAS:528:DC%2BC3cXis1aktro%3D, PID: 20043958
    • Moutzouris JP, Che W, Ramsay EE et al (2010) Proteasomal inhibition upregulates the endogenous MAPK deactivator MKP-1 in human airway smooth muscle: mechanism of action and effect on cytokine secretion. Biochim Biophys Acta 1803:416–423
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 416-423
    • Moutzouris, J.P.1    Che, W.2    Ramsay, E.E.3
  • 111
    • 0031806684 scopus 로고    scopus 로고
    • Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse
    • COI: 1:CAS:528:DyaK1cXjsF2rsb0%3D, PID: 9598845
    • Nakashima Y, Raines EW, Plump AS et al (1998) Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse. Arterioscler Thromb Vasc Biol 18:842–851
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 842-851
    • Nakashima, Y.1    Raines, E.W.2    Plump, A.S.3
  • 112
    • 33746862576 scopus 로고    scopus 로고
    • Naturally occurring NF-kappaB inhibitors
    • COI: 1:CAS:528:DC%2BD28XnslOksrw%3D, PID: 16918500
    • Nam NH (2006) Naturally occurring NF-kappaB inhibitors. Mini Rev Med Chem 6:945–951
    • (2006) Mini Rev Med Chem , vol.6 , pp. 945-951
    • Nam, N.H.1
  • 113
    • 35348816753 scopus 로고    scopus 로고
    • Nuclear factor-κB in thyroid carcinogenesis and progression: a novel therapeutic target for advanced thyroid cancer
    • Namba H, Saenko V, Yamashita S (2007) Nuclear factor-κB in thyroid carcinogenesis and progression: a novel therapeutic target for advanced thyroid cancer. Arq Bras Endocrinol Metab 51:843–851
    • (2007) Arq Bras Endocrinol Metab , vol.51 , pp. 843-851
    • Namba, H.1    Saenko, V.2    Yamashita, S.3
  • 114
    • 0037484097 scopus 로고    scopus 로고
    • NF-kappaB signalling is inhibited by glucocorticoid receptor and STAT6 via distinct mechanisms
    • COI: 1:CAS:528:DC%2BD3sXltFemtr4%3D, PID: 12734399
    • Nelson G, Wilde GJ, Spiller DG et al (2003) NF-kappaB signalling is inhibited by glucocorticoid receptor and STAT6 via distinct mechanisms. J Cell Sci 116(Pt 12):2495–2503
    • (2003) J Cell Sci , vol.116 , pp. 2495-2503
    • Nelson, G.1    Wilde, G.J.2    Spiller, D.G.3
  • 115
    • 68949097479 scopus 로고    scopus 로고
    • NIK is involved in constitutive activation of the alternative NF-κB pathway and proliferation of pancreatic cancer cells
    • COI: 1:CAS:528:DC%2BD1MXhtVehs7zN, PID: 19646419
    • Nishina T, Yamaguchi N, Gohda J et al (2009) NIK is involved in constitutive activation of the alternative NF-κB pathway and proliferation of pancreatic cancer cells. Biochem Biophys Res Commun 388:96–101
    • (2009) Biochem Biophys Res Commun , vol.388 , pp. 96-101
    • Nishina, T.1    Yamaguchi, N.2    Gohda, J.3
  • 116
    • 0028888708 scopus 로고
    • Long-term survival after resection for ductal adenocarcinoma of the pancreas. Is it really improving?
    • COI: 1:STN:280:DyaK2M7is1OhtQ%3D%3D, PID: 7826162
    • Nitecki SS, Sarr MG, Colby TV et al (1995) Long-term survival after resection for ductal adenocarcinoma of the pancreas. Is it really improving? Ann Surg 221:59
    • (1995) Ann Surg , vol.221 , pp. 59
    • Nitecki, S.S.1    Sarr, M.G.2    Colby, T.V.3
  • 117
    • 79959521145 scopus 로고    scopus 로고
    • MCP-1-induced protein attenuates endotoxin-induced myocardial dysfunction by suppressing cardiac NF-small ka, CyrillicB activation via inhibition of Ismall ka, Cyrillic B kinase activation
    • COI: 1:CAS:528:DC%2BC3MXotVeisr0%3D, PID: 21616078
    • Niu J, Wang K, Graham S et al (2011) MCP-1-induced protein attenuates endotoxin-induced myocardial dysfunction by suppressing cardiac NF-small ka, CyrillicB activation via inhibition of Ismall ka, Cyrillic B kinase activation. J Mol Cell Cardiol 51:177–186
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 177-186
    • Niu, J.1    Wang, K.2    Graham, S.3
  • 118
    • 84899917464 scopus 로고    scopus 로고
    • An update on molecular biology of thyroid cancers
    • PID: 24405857
    • Omur O, Baran Y (2014) An update on molecular biology of thyroid cancers. Crit Rev Oncol Hematol 90:233–252
    • (2014) Crit Rev Oncol Hematol , vol.90 , pp. 233-252
    • Omur, O.1    Baran, Y.2
  • 119
    • 84872541978 scopus 로고    scopus 로고
    • NF-κB in premature aging
    • COI: 1:CAS:528:DC%2BC3sXksVOjuw%3D%3D, PID: 23211391
    • Osorio FG, Lopez-Otin C, Freije JM (2012) NF-κB in premature aging. Aging 4:726–727
    • (2012) Aging , vol.4 , pp. 726-727
    • Osorio, F.G.1    Lopez-Otin, C.2    Freije, J.M.3
  • 120
    • 19944426112 scopus 로고    scopus 로고
    • Oncogenic and anti-apoptotic activity of NF-κB in human thyroid carcinomas
    • COI: 1:CAS:528:DC%2BD2cXhtVylur3L, PID: 15475567
    • Pacifico F, Mauro C, Barone C et al (2004) Oncogenic and anti-apoptotic activity of NF-κB in human thyroid carcinomas. J Biol Chem 279:54610–54619
    • (2004) J Biol Chem , vol.279 , pp. 54610-54619
    • Pacifico, F.1    Mauro, C.2    Barone, C.3
  • 121
    • 33751549248 scopus 로고    scopus 로고
    • BRAFV600E promotes invasiveness of thyroid cancer cells through nuclear factor κB activation
    • COI: 1:CAS:528:DC%2BD28Xht1yqtr%2FP, PID: 16959844
    • Palona I, Namba H, Mitsutake N et al (2006) BRAFV600E promotes invasiveness of thyroid cancer cells through nuclear factor κB activation. Endocrinology 147:5699–5707
    • (2006) Endocrinology , vol.147 , pp. 5699-5707
    • Palona, I.1    Namba, H.2    Mitsutake, N.3
  • 122
    • 84966283895 scopus 로고    scopus 로고
    • The high mobility group protein HMO1 functions as a linker histone in yeast
    • PID: 27030801
    • Panday A, Grove A (2016) The high mobility group protein HMO1 functions as a linker histone in yeast. Epigenetics Chromatin 9:13
    • (2016) Epigenetics Chromatin , vol.9 , pp. 13
    • Panday, A.1    Grove, A.2
  • 123
    • 84920520188 scopus 로고    scopus 로고
    • NADPH oxidases: an overview from structure to innate immunity-associated pathologies
    • COI: 1:CAS:528:DC%2BC2MXivFKksg%3D%3D, PID: 25263488
    • Panday A, Sahoo MK, Osorio D et al (2015a) NADPH oxidases: an overview from structure to innate immunity-associated pathologies. Cell Mol Immunol 12:5–23
    • (2015) Cell Mol Immunol , vol.12 , pp. 5-23
    • Panday, A.1    Sahoo, M.K.2    Osorio, D.3
  • 124
    • 84942089084 scopus 로고    scopus 로고
    • Yeast high mobility group protein HMO1 stabilizes chromatin and is evicted during repair of DNA double strand breaks
    • COI: 1:CAS:528:DC%2BC2MXhsFait7fE, PID: 25979266
    • Panday A, Xiao L, Grove A (2015b) Yeast high mobility group protein HMO1 stabilizes chromatin and is evicted during repair of DNA double strand breaks. Nucleic Acids Res 43:5759–5770
    • (2015) Nucleic Acids Res , vol.43 , pp. 5759-5770
    • Panday, A.1    Xiao, L.2    Grove, A.3
  • 125
    • 0030043446 scopus 로고    scopus 로고
    • Cancer statistics, 1997
    • COI: 1:STN:280:DyaK2s7kvFalug%3D%3D, PID: 8996076
    • Parker SL, Tong T, Bolden S et al (1997) Cancer statistics, 1997. CA Cancer J Clin 47:5–27
    • (1997) CA Cancer J Clin , vol.47 , pp. 5-27
    • Parker, S.L.1    Tong, T.2    Bolden, S.3
  • 126
    • 77957578387 scopus 로고    scopus 로고
    • Inhibition of cancer cell invasion and metastasis by genistein
    • COI: 1:CAS:528:DC%2BC3cXhtFWqt7rJ, PID: 20730632
    • Pavese JM, Farmer RL, Bergan RC (2010) Inhibition of cancer cell invasion and metastasis by genistein. Cancer Metastasis Rev 29:465–482
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 465-482
    • Pavese, J.M.1    Farmer, R.L.2    Bergan, R.C.3
  • 127
    • 0029870463 scopus 로고    scopus 로고
    • Salicylates inhibit I kappa B-alpha phosphorylation, endothelial-leukocyte adhesion molecule expression, and neutrophil transmigration
    • COI: 1:CAS:528:DyaK28XivVamsbw%3D, PID: 8621937
    • Pierce JW, Read MA, Ding H et al (1996) Salicylates inhibit I kappa B-alpha phosphorylation, endothelial-leukocyte adhesion molecule expression, and neutrophil transmigration. J Immunol 156:3961–3969
    • (1996) J Immunol , vol.156 , pp. 3961-3969
    • Pierce, J.W.1    Read, M.A.2    Ding, H.3
  • 128
    • 78751690674 scopus 로고    scopus 로고
    • Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management
    • COI: 1:CAS:528:DC%2BC3MXisVyjs78%3D, PID: 21078929
    • Piret J, Boivin G (2011) Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management. Antimicrob Agents Chemother 55:459–472
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 459-472
    • Piret, J.1    Boivin, G.2
  • 129
    • 84872777798 scopus 로고    scopus 로고
    • Cigarette smoke induced airway inflammation is independent of NF-κB signalling
    • COI: 1:CAS:528:DC%2BC3sXhvF2gsrs%3D, PID: 23349803
    • Rastrick J, Stevenson CS, Eltom S et al (2013) Cigarette smoke induced airway inflammation is independent of NF-κB signalling. PLoS One 8:e54128
    • (2013) PLoS One , vol.8
    • Rastrick, J.1    Stevenson, C.S.2    Eltom, S.3
  • 130
    • 84858064027 scopus 로고    scopus 로고
    • The involvement of NF-?B Transcription factor in asthma
    • PID: 21967970
    • Rico-Rosillo G, Vega-Robledo GB (2011) The involvement of NF-?B Transcription factor in asthma. Rev Alerg Mex 58:107–111
    • (2011) Rev Alerg Mex , vol.58 , pp. 107-111
    • Rico-Rosillo, G.1    Vega-Robledo, G.B.2
  • 131
    • 0025139429 scopus 로고
    • 1.3E2, a variant of the B lymphoma 70Z/3, defective in activation of NF-kappa B and OTF-2
    • COI: 1:CAS:528:DyaK3cXktlyltLg%3D, PID: 1689272
    • Rooney JW, Emery DW, Sibley CH (1990) 1.3E2, a variant of the B lymphoma 70Z/3, defective in activation of NF-kappa B and OTF-2. Immunogenetics 31:73–78
    • (1990) Immunogenetics , vol.31 , pp. 73-78
    • Rooney, J.W.1    Emery, D.W.2    Sibley, C.H.3
  • 132
    • 33646752928 scopus 로고    scopus 로고
    • Transcription factors in asthma: are transcription factors a new target for asthma therapy?
    • COI: 1:CAS:528:DC%2BD28Xkt1Ghsbs%3D, PID: 16719769
    • Roth M, Black JL (2006) Transcription factors in asthma: are transcription factors a new target for asthma therapy? Curr Drug Targets 7:589–595
    • (2006) Curr Drug Targets , vol.7 , pp. 589-595
    • Roth, M.1    Black, J.L.2
  • 133
    • 84957573127 scopus 로고    scopus 로고
    • N-acetylcysteine in COPD: why, how, and when?
    • PID: 26855777
    • Sanguinetti CM (2015) N-acetylcysteine in COPD: why, how, and when? Multidiscip Respir Med 11:8
    • (2015) Multidiscip Respir Med , vol.11 , pp. 8
    • Sanguinetti, C.M.1
  • 134
    • 36149000984 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) activates nuclear factor-κB through IκBα kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IκBα
    • COI: 1:CAS:528:DC%2BD2sXhtlWjtrzO, PID: 17533369
    • Sethi G, Ahn K, Chaturvedi M et al (2007) Epidermal growth factor (EGF) activates nuclear factor-κB through IκBα kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IκBα. Oncogene 26:7324–7332
    • (2007) Oncogene , vol.26 , pp. 7324-7332
    • Sethi, G.1    Ahn, K.2    Chaturvedi, M.3
  • 135
    • 84895071589 scopus 로고    scopus 로고
    • Activation of NF-κB: bridging the gap between inflammation and cancer in colitis-mediated colon carcinogenesis
    • COI: 1:CAS:528:DC%2BC3sXhs1Oqtb%2FJ, PID: 24269000
    • Setia S, Nehru B, Sanyal SN (2014) Activation of NF-κB: bridging the gap between inflammation and cancer in colitis-mediated colon carcinogenesis. Biomed Pharmacother 68:119–128
    • (2014) Biomed Pharmacother , vol.68 , pp. 119-128
    • Setia, S.1    Nehru, B.2    Sanyal, S.N.3
  • 136
    • 78650591264 scopus 로고    scopus 로고
    • HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-kappaB pathway and can be silenced by gp120-specific siRNA
    • COI: 1:CAS:528:DC%2BC3MXpt1aitQ%3D%3D
    • Shah A, Kumar A (2010) HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-kappaB pathway and can be silenced by gp120-specific siRNA. J Neuroinflamm 7:96
    • (2010) J Neuroinflamm , vol.7 , pp. 96
    • Shah, A.1    Kumar, A.2
  • 137
    • 79959330425 scopus 로고    scopus 로고
    • HIV-1 gp120 induces expression of IL-6 through a nuclear factor-kappa B-dependent mechanism: suppression by gp120 specific small interfering RNA
    • COI: 1:CAS:528:DC%2BC3MXotFals78%3D, PID: 21712995
    • Shah A, Verma AS, Patel KH et al (2011) HIV-1 gp120 induces expression of IL-6 through a nuclear factor-kappa B-dependent mechanism: suppression by gp120 specific small interfering RNA. PLoS One 6:e21261
    • (2011) PLoS One , vol.6
    • Shah, A.1    Verma, A.S.2    Patel, K.H.3
  • 138
    • 84930750967 scopus 로고    scopus 로고
    • A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes
    • COI: 1:CAS:528:DC%2BC2MXhsVyhs7jO, PID: 25586491
    • Sharma A, Menche J, Huang C et al (2015) A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes. Hum Mol Genet 24:3005–3020
    • (2015) Hum Mol Genet , vol.24 , pp. 3005-3020
    • Sharma, A.1    Menche, J.2    Huang, C.3
  • 139
    • 84864011388 scopus 로고    scopus 로고
    • Dehydroxymethylepoxyquinomicin (DHMEQ), a novel NF-kappaB inhibitor, inhibits allergic inflammation and airway remodelling in murine models of asthma
    • COI: 1:CAS:528:DC%2BC38XhtFOms7rJ, PID: 22805475
    • Shimizu K, Konno S, Ozaki M et al (2012) Dehydroxymethylepoxyquinomicin (DHMEQ), a novel NF-kappaB inhibitor, inhibits allergic inflammation and airway remodelling in murine models of asthma. Clin Exp Allergy 42:1273–1281
    • (2012) Clin Exp Allergy , vol.42 , pp. 1273-1281
    • Shimizu, K.1    Konno, S.2    Ozaki, M.3
  • 140
    • 84860864158 scopus 로고    scopus 로고
    • NF-κB, stem cells and breast cancer: the links get stronger
    • PID: 21867572
    • Shostak K, Chariot KS (2011) NF-κB, stem cells and breast cancer: the links get stronger. Breast Cancer Res 13:214
    • (2011) Breast Cancer Res , vol.13 , pp. 214
    • Shostak, K.1    Chariot, K.S.2
  • 141
    • 84879812284 scopus 로고    scopus 로고
    • HIV-1-related central nervous system disease: current issues in pathogenesis, diagnosis, and treatment
    • Spudich S, González-Scarano F (2012) HIV-1-related central nervous system disease: current issues in pathogenesis, diagnosis, and treatment. Cold Spring Harbor Perspect Med 2:a007120
    • (2012) Cold Spring Harbor Perspect Med , vol.2 , pp. a007120
    • Spudich, S.1    González-Scarano, F.2
  • 142
    • 78650883911 scopus 로고    scopus 로고
    • Regulation of NF-kappaB signaling by caspases and MALT1 paracaspase
    • COI: 1:CAS:528:DC%2BC3MXhtlaqsw%3D%3D, PID: 21119681
    • Staal J, Bekaert T, Beyaert R (2011) Regulation of NF-kappaB signaling by caspases and MALT1 paracaspase. Cell Res 21:40–54
    • (2011) Cell Res , vol.21 , pp. 40-54
    • Staal, J.1    Bekaert, T.2    Beyaert, R.3
  • 143
    • 70449102637 scopus 로고    scopus 로고
    • A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation
    • COI: 1:CAS:528:DC%2BD1MXhsFOlt7jO, PID: 19917246
    • Stilmann M, Hinz M, Arslan SC et al (2009) A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation. Mol Cell 36:365–378
    • (2009) Mol Cell , vol.36 , pp. 365-378
    • Stilmann, M.1    Hinz, M.2    Arslan, S.C.3
  • 144
    • 34447640381 scopus 로고    scopus 로고
    • A new role for NF-[kappa]B in angiogenesis inhibition
    • COI: 1:CAS:528:DC%2BD2sXnvVemur0%3D, PID: 17464324
    • Tabruyn SP, Griffioen AW (2007) A new role for NF-[kappa]B in angiogenesis inhibition. Cell Death Differ 14:1393–1397
    • (2007) Cell Death Differ , vol.14 , pp. 1393-1397
    • Tabruyn, S.P.1    Griffioen, A.W.2
  • 145
    • 6344256840 scopus 로고    scopus 로고
    • Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus
    • COI: 1:CAS:528:DC%2BD2cXptVKmu7o%3D, PID: 15479802
    • Taddeo B, Zhang W, Lakeman F et al (2004) Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus. J Virol 78:11615–11621
    • (2004) J Virol , vol.78 , pp. 11615-11621
    • Taddeo, B.1    Zhang, W.2    Lakeman, F.3
  • 146
    • 73649112422 scopus 로고    scopus 로고
    • Tobacco smoke promotes lung tumorigenesis by triggering IKKβ-and JNK1-dependent inflammation
    • COI: 1:CAS:528:DC%2BC3cXkvFKgs7c%3D, PID: 20129250
    • Takahashi H, Ogata H, Nishigaki R et al (2010) Tobacco smoke promotes lung tumorigenesis by triggering IKKβ-and JNK1-dependent inflammation. Cancer Cell 17:89–97
    • (2010) Cancer Cell , vol.17 , pp. 89-97
    • Takahashi, H.1    Ogata, H.2    Nishigaki, R.3
  • 147
    • 84928574211 scopus 로고    scopus 로고
    • Diversity of heparan sulfate and HSV entry: basic understanding and treatment strategies
    • PID: 25665065
    • Tiwari V, Tarbutton MS, Shukla D (2015) Diversity of heparan sulfate and HSV entry: basic understanding and treatment strategies. Molecules 20:2707–2727
    • (2015) Molecules , vol.20 , pp. 2707-2727
    • Tiwari, V.1    Tarbutton, M.S.2    Shukla, D.3
  • 148
    • 84907970648 scopus 로고    scopus 로고
    • Cancer-selective targeting of the NF-kappaB survival pathway with GADD45beta/MKK7 inhibitors
    • COI: 1:CAS:528:DC%2BC2cXhslGnsLzJ, PID: 25314077
    • Tornatore L, Sandomenico A, Raimondo D et al (2014) Cancer-selective targeting of the NF-kappaB survival pathway with GADD45beta/MKK7 inhibitors. Cancer Cell 26:495–508
    • (2014) Cancer Cell , vol.26 , pp. 495-508
    • Tornatore, L.1    Sandomenico, A.2    Raimondo, D.3
  • 149
    • 27844607415 scopus 로고    scopus 로고
    • Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae
    • COI: 1:CAS:528:DC%2BD2MXht1WksbbL, PID: 16292314
    • Tsukuda T, Fleming AB, Nickoloff JA et al (2005) Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae. Nature 438:379–383
    • (2005) Nature , vol.438 , pp. 379-383
    • Tsukuda, T.1    Fleming, A.B.2    Nickoloff, J.A.3
  • 150
    • 67650724069 scopus 로고    scopus 로고
    • Regulation and function of NF-kappaB transcription factors in the immune system
    • COI: 1:CAS:528:DC%2BD1MXlsFSlt7o%3D, PID: 19302050
    • Vallabhapurapu S, Karin M (2009) Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 27:693–733
    • (2009) Annu Rev Immunol , vol.27 , pp. 693-733
    • Vallabhapurapu, S.1    Karin, M.2
  • 151
    • 57149130824 scopus 로고    scopus 로고
    • AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential
    • COI: 1:CAS:528:DC%2BD1MXht1Whu74%3D, PID: 18798739
    • Vij N (2008) AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential. J Cell Mol Med 12:2511–2518
    • (2008) J Cell Mol Med , vol.12 , pp. 2511-2518
    • Vij, N.1
  • 152
    • 0030666532 scopus 로고    scopus 로고
    • Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFkB p65 protein expression
    • COI: 1:CAS:528:DyaK2sXntFegtr4%3D, PID: 9365245
    • Visconti R, Cerutti J, Battista S et al (1997) Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFkB p65 protein expression. Oncogene 15:1987–1994
    • (1997) Oncogene , vol.15 , pp. 1987-1994
    • Visconti, R.1    Cerutti, J.2    Battista, S.3
  • 153
    • 84855285493 scopus 로고    scopus 로고
    • NF-kappaB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes
    • COI: 1:CAS:528:DC%2BC38Xit1Gntw%3D%3D, PID: 21908405
    • Volcic M, Karl S, Baumann B et al (2012) NF-kappaB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes. Nucleic Acids Res 40:181–195
    • (2012) Nucleic Acids Res , vol.40 , pp. 181-195
    • Volcic, M.1    Karl, S.2    Baumann, B.3
  • 154
    • 77956476392 scopus 로고    scopus 로고
    • MicroRNAs: synthesis, mechanism, function, and recent clinical trials
    • COI: 1:CAS:528:DC%2BC3cXhtFGjsbnE, PID: 20619301
    • Wahid F, Shehzad A, Khan T et al (2010) MicroRNAs: synthesis, mechanism, function, and recent clinical trials. Biochim Biophys Acta 1803:1231–1243
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 1231-1243
    • Wahid, F.1    Shehzad, A.2    Khan, T.3
  • 155
    • 55149097289 scopus 로고    scopus 로고
    • Tumor necrosis factor and cancer, buddies or foes&quest
    • Wang X, Lin Y (2008) Tumor necrosis factor and cancer, buddies or foes&quest. Acta Pharmacol Sinica 29:1275–1288
    • (2008) Acta Pharmacol Sinica , vol.29 , pp. 1275-1288
    • Wang, X.1    Lin, Y.2
  • 156
    • 0029858387 scopus 로고    scopus 로고
    • TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB
    • COI: 1:CAS:528:DyaK28XmsFOhu7Y%3D, PID: 8864119
    • Wang C-Y, Mayo MW, Baldwin AS (1996) TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 274:784–787
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.-Y.1    Mayo, M.W.2    Baldwin, A.S.3
  • 157
    • 0032943591 scopus 로고    scopus 로고
    • The nuclear factor-κB RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells
    • COI: 1:CAS:528:DyaK1MXhtVShtLY%3D, PID: 9918209
    • Wang W, Abbruzzese JL, Evans DB et al (1999) The nuclear factor-κB RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res 5:119–127
    • (1999) Clin Cancer Res , vol.5 , pp. 119-127
    • Wang, W.1    Abbruzzese, J.L.2    Evans, D.B.3
  • 158
    • 84863339591 scopus 로고    scopus 로고
    • Phase II study of panobinostat and bortezomib in patients with pancreatic cancer progressing on gemcitabine-based therapy
    • COI: 1:CAS:528:DC%2BC38Xls1aktLc%3D, PID: 22399627
    • Wang H, Cao Q, Dudek AZ (2012) Phase II study of panobinostat and bortezomib in patients with pancreatic cancer progressing on gemcitabine-based therapy. Anticancer Res 32:1027–1031
    • (2012) Anticancer Res , vol.32 , pp. 1027-1031
    • Wang, H.1    Cao, Q.2    Dudek, A.Z.3
  • 159
    • 84901045151 scopus 로고    scopus 로고
    • Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death
    • COI: 1:CAS:528:DC%2BC2cXnsVWru7s%3D, PID: 24799678
    • Weng D, Marty-Roix R, Ganesan S et al (2014) Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death. Proc Natl Acad Sci 111:7391–7396
    • (2014) Proc Natl Acad Sci , vol.111 , pp. 7391-7396
    • Weng, D.1    Marty-Roix, R.2    Ganesan, S.3
  • 160
    • 85046913982 scopus 로고    scopus 로고
    • Constitutive noncanonical NFκB signaling in pancreatic cancer cells
    • COI: 1:CAS:528:DC%2BC3cXks1Clurg%3D, PID: 19502791
    • Wharry CE, Haines KM, Carroll RG et al (2009) Constitutive noncanonical NFκB signaling in pancreatic cancer cells. Cancer Biol Ther 8:1567–1576
    • (2009) Cancer Biol Ther , vol.8 , pp. 1567-1576
    • Wharry, C.E.1    Haines, K.M.2    Carroll, R.G.3
  • 161
    • 0035883733 scopus 로고    scopus 로고
    • Effects of budesonide and formoterol on NF-kappaB, adhesion molecules, and cytokines in asthma
    • COI: 1:STN:280:DC%2BD3MrktV2jsA%3D%3D, PID: 11587995
    • Wilson SJ, Wallin A, Della-Cioppa G et al (2001) Effects of budesonide and formoterol on NF-kappaB, adhesion molecules, and cytokines in asthma. Am J Respir Crit Care Med 164:1047–1052
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1047-1052
    • Wilson, S.J.1    Wallin, A.2    Della-Cioppa, G.3
  • 162
    • 1542269021 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors: a new approach for asthma
    • COI: 1:CAS:528:DC%2BD2cXitFKls7w%3D, PID: 15023350
    • Wong WS, Leong KP (2004) Tyrosine kinase inhibitors: a new approach for asthma. Biochim Biophys Acta 1697:53–69
    • (2004) Biochim Biophys Acta , vol.1697 , pp. 53-69
    • Wong, W.S.1    Leong, K.P.2
  • 163
    • 77950799529 scopus 로고    scopus 로고
    • NF-kappaB fans the flames of lung carcinogenesis
    • COI: 1:CAS:528:DC%2BC3cXht1Wjs7zP
    • Wong K, Jacks T, Dranoff G (2010) NF-kappaB fans the flames of lung carcinogenesis. Cancer Prev Res 3:403–405
    • (2010) Cancer Prev Res , vol.3 , pp. 403-405
    • Wong, K.1    Jacks, T.2    Dranoff, G.3
  • 164
    • 2642705014 scopus 로고    scopus 로고
    • Antiviral therapy of herpes simplex and varicella-zoster virus infections
    • COI: 1:CAS:528:DyaK1cXltFCltb4%3D, PID: 9675639
    • Wutzler P (1997) Antiviral therapy of herpes simplex and varicella-zoster virus infections. Intervirology 40:343–356
    • (1997) Intervirology , vol.40 , pp. 343-356
    • Wutzler, P.1
  • 165
    • 0035139792 scopus 로고    scopus 로고
    • Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer
    • COI: 1:CAS:528:DC%2BD3MXkvVCitg%3D%3D, PID: 11160126
    • Yamamoto Y, Gaynor RB (2001) Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. J Clin Invest 107:135–142
    • (2001) J Clin Invest , vol.107 , pp. 135-142
    • Yamamoto, Y.1    Gaynor, R.B.2
  • 166
    • 0032568792 scopus 로고    scopus 로고
    • Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
    • COI: 1:CAS:528:DyaK1cXksVSqsLs%3D, PID: 9657155
    • Yamaoka S, Courtois G, Bessia C et al (1998) Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell 93:1231–1240
    • (1998) Cell , vol.93 , pp. 1231-1240
    • Yamaoka, S.1    Courtois, G.2    Bessia, C.3
  • 167
    • 79954612742 scopus 로고    scopus 로고
    • The biphasic role of NF-κB in progression and chemoresistance of ovarian cancer
    • COI: 1:CAS:528:DC%2BC3MXkslCgsLk%3D, PID: 21339307
    • Yang G, Xiao X, Rosen DG et al (2011) The biphasic role of NF-κB in progression and chemoresistance of ovarian cancer. Clin Cancer Res 17:2181–2194
    • (2011) Clin Cancer Res , vol.17 , pp. 2181-2194
    • Yang, G.1    Xiao, X.2    Rosen, D.G.3
  • 168
    • 0032487857 scopus 로고    scopus 로고
    • The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta
    • COI: 1:CAS:528:DyaK1cXnsVSjur0%3D, PID: 9817203
    • Yin MJ, Yamamoto Y, Gaynor RB (1998) The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature 396:77–80
    • (1998) Nature , vol.396 , pp. 77-80
    • Yin, M.J.1    Yamamoto, Y.2    Gaynor, R.B.3
  • 169
    • 70849134670 scopus 로고    scopus 로고
    • NF-κB activation is required for adaptive cardiac hypertrophy
    • COI: 1:CAS:528:DC%2BD1MXhsVGnurfE, PID: 19620128
    • Zelarayan L, Renger A, Noack C et al (2009) NF-κB activation is required for adaptive cardiac hypertrophy. Cardiovasc Res 84:416–424
    • (2009) Cardiovasc Res , vol.84 , pp. 416-424
    • Zelarayan, L.1    Renger, A.2    Noack, C.3
  • 170
    • 84949580007 scopus 로고    scopus 로고
    • Effect of oral N-acetylcysteine on COPD patients with microsatellite polymorphism in the heme oxygenase-1 gene promoter
    • PID: 26674585
    • Zhang JQ, Zhang JQ, Fang LZ et al (2015) Effect of oral N-acetylcysteine on COPD patients with microsatellite polymorphism in the heme oxygenase-1 gene promoter. Drug Des Devel Ther 9:6379–6387
    • (2015) Drug Des Devel Ther , vol.9 , pp. 6379-6387
    • Zhang, J.Q.1    Zhang, J.Q.2    Fang, L.Z.3
  • 171
    • 0036203419 scopus 로고    scopus 로고
    • The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
    • COI: 1:CAS:528:DC%2BD38XivVylt7k%3D, PID: 11931769
    • Zhong H, May MJ, Jimi E et al (2002) The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell 9:625–636
    • (2002) Mol Cell , vol.9 , pp. 625-636
    • Zhong, H.1    May, M.J.2    Jimi, E.3
  • 172
    • 84902492262 scopus 로고    scopus 로고
    • Heat-shock protein 90 promotes nuclear transport of herpes simplex virus 1 capsid protein by interacting with acetylated tubulin
    • PID: 24901434
    • Zhong M, Zheng K, Chen M et al (2014) Heat-shock protein 90 promotes nuclear transport of herpes simplex virus 1 capsid protein by interacting with acetylated tubulin. PLoS One 9:e99425
    • (2014) PLoS One , vol.9
    • Zhong, M.1    Zheng, K.2    Chen, M.3


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