-
1
-
-
2342613652
-
The proteasome: A suitable antineoplastic target
-
Adams J 2004 The proteasome: a suitable antineoplastic target. Nat Rev Cancer 4:349-360
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 349-360
-
-
Adams, J.1
-
2
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson PG, Barlogie B, Berenson J, Singhal S, Jagannath S, Irwin D, Rajkumar SV, Srkalovic G, Alsina M, Alexanian R, Siegel D, Orlowski RZ, Kuter D, Limentani SA, Lee S, Hideshima T, Esseltine DL, Kauffman M, Adams J, Schenkein DP, Anderson KC 2003 A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 348:2609-2617
-
(2003)
N Engl J Med
, vol.348
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.6
Rajkumar, S.V.7
Srkalovic, G.8
Alsina, M.9
Alexanian, R.10
Siegel, D.11
Orlowski, R.Z.12
Kuter, D.13
Limentani, S.A.14
Lee, S.15
Hideshima, T.16
Esseltine, D.L.17
Kauffman, M.18
Adams, J.19
Schenkein, D.P.20
Anderson, K.C.21
more..
-
3
-
-
2442510143
-
Phase II trial of PS-341 in patients with renal cell cancer: A University of Chicago phase II consortium study
-
Davis NB, Taber DA, Ansari RH, Ryan CW, George C, Vokes EE, Vogelzang NJ, Stadler WM 2004 Phase II trial of PS-341 in patients with renal cell cancer: a University of Chicago phase II consortium study. J Clin Oncol 22:115-119
-
(2004)
J Clin Oncol
, vol.22
, pp. 115-119
-
-
Davis, N.B.1
Taber, D.A.2
Ansari, R.H.3
Ryan, C.W.4
George, C.5
Vokes, E.E.6
Vogelzang, N.J.7
Stadler, W.M.8
-
4
-
-
2942692143
-
Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer
-
Papandreou CN, Daliani DD, Nix D, Yang H, Madden T, Wang X, Pien CS, Millikan RE, Tu SM, Pagliaro L, Kim J, Adams J, Elliott P, Esseltine D, Petrusich A, Dieringer P, Perez C, Logothetis CJ 2004 Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J Clin Oncol 22:2108-2121
-
(2004)
J Clin Oncol
, vol.22
, pp. 2108-2121
-
-
Papandreou, C.N.1
Daliani, D.D.2
Nix, D.3
Yang, H.4
Madden, T.5
Wang, X.6
Pien, C.S.7
Millikan, R.E.8
Tu, S.M.9
Pagliaro, L.10
Kim, J.11
Adams, J.12
Elliott, P.13
Esseltine, D.14
Petrusich, A.15
Dieringer, P.16
Perez, C.17
Logothetis, C.J.18
-
5
-
-
0036624741
-
Biologic sequelae of nuclear factor-κB blockade in multiple myeloma: Therapeutic applications
-
Mitsiades N, Mitsiades CS, Poulaki V, Chauhan D, Richardson PG, Hideshima T, Munshi N, Treon SP, Anderson KC 2002 Biologic sequelae of nuclear factor-κB blockade in multiple myeloma: therapeutic applications. Blood 99:4079-4086
-
(2002)
Blood
, vol.99
, pp. 4079-4086
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Richardson, P.G.5
Hideshima, T.6
Munshi, N.7
Treon, S.P.8
Anderson, K.C.9
-
6
-
-
0037443551
-
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
-
Mitsiades N, Mitsiades CS, Richardson PG, Poulaki V, Tai YT, Chauhan D, Fanourakis G, Gu X, Bailey C, Joseph M, Libermann TA, Schlossman R, Munshi NC, Hideshima T, Anderson KC 2003 The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 101:2377-2380
-
(2003)
Blood
, vol.101
, pp. 2377-2380
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
Poulaki, V.4
Tai, Y.T.5
Chauhan, D.6
Fanourakis, G.7
Gu, X.8
Bailey, C.9
Joseph, M.10
Libermann, T.A.11
Schlossman, R.12
Munshi, N.C.13
Hideshima, T.14
Anderson, K.C.15
-
7
-
-
0242496212
-
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
-
Mitsiades N, Mitsiades CS, Poulaki V, Chauhan D, Fanourakis G, Gu X, Bailey C, Joseph M, Libermann TA, Treon SP, Munshi NC, Richardson PG, Hideshima T, Anderson KC 2002 Molecular sequelae of proteasome inhibition in human multiple myeloma cells. Proc Natl Acad Sci USA 99:14374-14379
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14374-14379
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Fanourakis, G.5
Gu, X.6
Bailey, C.7
Joseph, M.8
Libermann, T.A.9
Treon, S.P.10
Munshi, N.C.11
Richardson, P.G.12
Hideshima, T.13
Anderson, K.C.14
-
8
-
-
12944271053
-
Cancer statistics, 2005
-
Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, Feuer EJ, Thun MJ 2005 Cancer statistics, 2005. CA Cancer J Clin 55:10-30
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 10-30
-
-
Jemal, A.1
Murray, T.2
Ward, E.3
Samuels, A.4
Tiwari, R.C.5
Ghafoor, A.6
Feuer, E.J.7
Thun, M.J.8
-
9
-
-
19944426112
-
Oncogenic and anti-apoptotic activity of NF-κB in human thyroid carcinomas
-
Pacifico F, Mauro C, Barone C, Crescenzi E, Mellone S, Monaco M, Chiappetta G, Terrazzano G, Liguoro D, Vito P, Consiglio E, Formisano S, Leonardi A 2004 Oncogenic and anti-apoptotic activity of NF-κB in human thyroid carcinomas. J Biol Chem 279:54610-54619
-
(2004)
J Biol Chem
, vol.279
, pp. 54610-54619
-
-
Pacifico, F.1
Mauro, C.2
Barone, C.3
Crescenzi, E.4
Mellone, S.5
Monaco, M.6
Chiappetta, G.7
Terrazzano, G.8
Liguoro, D.9
Vito, P.10
Consiglio, E.11
Formisano, S.12
Leonardi, A.13
-
10
-
-
0035354187
-
Nuclear factor-κB is constitutively active in C-cell carcinoma and required for RET-induced transformation
-
Ludwig L, Kessler H, Wagner M, Hoang-Vu C, Dralle H, Adler G, Bohm BO, Schmid RM 2001 Nuclear factor-κB is constitutively active in C-cell carcinoma and required for RET-induced transformation. Cancer Res 61:4526-4535
-
(2001)
Cancer Res
, vol.61
, pp. 4526-4535
-
-
Ludwig, L.1
Kessler, H.2
Wagner, M.3
Hoang-Vu, C.4
Dralle, H.5
Adler, G.6
Bohm, B.O.7
Schmid, R.M.8
-
11
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
Fagin JA, Matsuo K, Karmakar A, Chen DL, Tang SH, Koeffler HP 1993 High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 91:179-184
-
(1993)
J Clin Invest
, vol.91
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
Chen, D.L.4
Tang, S.H.5
Koeffler, H.P.6
-
12
-
-
0030984102
-
Identification of rapid turnover transcripts overexpressed in thyroid tumors and thyroid cancer cell lines: Use of a targeted differential RNA display method to select for mRNA subsets
-
Gonsky R, Knauf JA, Elisei R, Wang JW, Su S, Fagin JA 1997 Identification of rapid turnover transcripts overexpressed in thyroid tumors and thyroid cancer cell lines: use of a targeted differential RNA display method to select for mRNA subsets. Nucleic Acids Res 25:3823-3831
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3823-3831
-
-
Gonsky, R.1
Knauf, J.A.2
Elisei, R.3
Wang, J.W.4
Su, S.5
Fagin, J.A.6
-
13
-
-
0031158864
-
Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines
-
Ain KB, Taylor KD, Tofiq S, Venkataraman G 1997 Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines. J Clin Endocrinol Metab 82:1857-1862
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 1857-1862
-
-
Ain, K.B.1
Taylor, K.D.2
Tofiq, S.3
Venkataraman, G.4
-
14
-
-
0035437171
-
TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: Therapeutic applications
-
Mitsiades CS, Treon SP, Mitsiades N, Shima Y, Richardson P, Schlossman R, Hideshima T, Anderson KC 2001 TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications. Blood 98:795-804
-
(2001)
Blood
, vol.98
, pp. 795-804
-
-
Mitsiades, C.S.1
Treon, S.P.2
Mitsiades, N.3
Shima, Y.4
Richardson, P.5
Schlossman, R.6
Hideshima, T.7
Anderson, K.C.8
-
15
-
-
0029108598
-
Selective recognition of the activated form of transcription factor NF-κB by a monoclonal antibody
-
Kaltschmidt C, Kaltschmidt B, Henkel T, Stockinger H, Baeuerle PA 1995 Selective recognition of the activated form of transcription factor NF-κB by a monoclonal antibody. Biol Chem Hoppe Seyler 376:9-16
-
(1995)
Biol Chem Hoppe Seyler
, vol.376
, pp. 9-16
-
-
Kaltschmidt, C.1
Kaltschmidt, B.2
Henkel, T.3
Stockinger, H.4
Baeuerle, P.A.5
-
16
-
-
0033883775
-
Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand
-
Mitsiades N, Poulaki V, Tseleni-Balafouta S, Koutras DA, Stamenkovic I 2000 Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand. Cancer Res 60:4122-4129
-
(2000)
Cancer Res
, vol.60
, pp. 4122-4129
-
-
Mitsiades, N.1
Poulaki, V.2
Tseleni-Balafouta, S.3
Koutras, D.A.4
Stamenkovic, I.5
-
17
-
-
0842334493
-
Inhibition of nuclear factor-κB cascade potentiates the effect of a combination treatment of anaplastic thyroid cancer cells
-
Starenki D, Namba H, Saenko V, Ohtsuru A, Yamashita S 2004 Inhibition of nuclear factor-κB cascade potentiates the effect of a combination treatment of anaplastic thyroid cancer cells. J Clin Endocrinol Metab 89:410-418
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 410-418
-
-
Starenki, D.1
Namba, H.2
Saenko, V.3
Ohtsuru, A.4
Yamashita, S.5
-
19
-
-
12144290914
-
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
-
Mitsiades CS, Mitsiades NS, McMullan CJ, Poulaki V, Shringarpure R, Akiyama M, Hideshima T, Chauhan D, Joseph M, Libermann TA, Garcia-Echeverria C, Pearson MA, Hofmann F, Anderson KC, Kung AL 2004 Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors. Cancer Cell 5:221-230
-
(2004)
Cancer Cell
, vol.5
, pp. 221-230
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
Poulaki, V.4
Shringarpure, R.5
Akiyama, M.6
Hideshima, T.7
Chauhan, D.8
Joseph, M.9
Libermann, T.A.10
Garcia-Echeverria, C.11
Pearson, M.A.12
Hofmann, F.13
Anderson, K.C.14
Kung, A.L.15
-
20
-
-
0037158513
-
Activation of NF-κB and up-regulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: Therapeutic implications
-
Mitsiades CS, Mitsiades N, Poulaki V, Schlossman R, Akiyama M, Chauhan D, Hideshima T, Treon SP, Munshi NC, Richardson PG, Anderson KC 2002 Activation of NF-κB and up-regulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications. Oncogene 21:5673-5683
-
(2002)
Oncogene
, vol.21
, pp. 5673-5683
-
-
Mitsiades, C.S.1
Mitsiades, N.2
Poulaki, V.3
Schlossman, R.4
Akiyama, M.5
Chauhan, D.6
Hideshima, T.7
Treon, S.P.8
Munshi, N.C.9
Richardson, P.G.10
Anderson, K.C.11
-
21
-
-
26244437260
-
Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma
-
Landriscina M, Fabiano A, Altamura S, Bagala C, Piscazzi A, Cassano A, Spadafora C, Giorgino F, Barone C, Cignarelli M 2005 Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma. J Clin Endocrinol Metab 90:5663-5671
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 5663-5671
-
-
Landriscina, M.1
Fabiano, A.2
Altamura, S.3
Bagala, C.4
Piscazzi, A.5
Cassano, A.6
Spadafora, C.7
Giorgino, F.8
Barone, C.9
Cignarelli, M.10
-
22
-
-
0036599406
-
p53 stabilization is decreased upon NFκB activation: A role for NFκB in acquisition of resistance to chemotherapy
-
Tergaonkar V, Pando M, Vafa O, Wahl G, Verma I 2002 p53 stabilization is decreased upon NFκB activation: a role for NFκB in acquisition of resistance to chemotherapy. Cancer Cell 1:493-503
-
(2002)
Cancer Cell
, vol.1
, pp. 493-503
-
-
Tergaonkar, V.1
Pando, M.2
Vafa, O.3
Wahl, G.4
Verma, I.5
-
23
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T, Tanaka N 2000 Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288:1053-1058
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
24
-
-
22244454745
-
Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: Therapeutic implications
-
Fernandez Y, Verhaegen M, Miller TP, Rush JL, Steiner P, Opipari Jr AW, Lowe SW, Soengas MS 2005 Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications. Cancer Res 65:6294-6304
-
(2005)
Cancer Res
, vol.65
, pp. 6294-6304
-
-
Fernandez, Y.1
Verhaegen, M.2
Miller, T.P.3
Rush, J.L.4
Steiner, P.5
Opipari Jr., A.W.6
Lowe, S.W.7
Soengas, M.S.8
-
25
-
-
22244452016
-
Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells
-
Qin JZ, Ziffra J, Stennett L, Bodner B, Bonish BK, Chaturvedi V, Bennett F, Pollock PM, Trent JM, Hendrix MJ, Rizzo P, Miele L, Nickoloff BJ 2005 Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells. Cancer Res 65:6282-6293
-
(2005)
Cancer Res
, vol.65
, pp. 6282-6293
-
-
Qin, J.Z.1
Ziffra, J.2
Stennett, L.3
Bodner, B.4
Bonish, B.K.5
Chaturvedi, V.6
Bennett, F.7
Pollock, P.M.8
Trent, J.M.9
Hendrix, M.J.10
Rizzo, P.11
Miele, L.12
Nickoloff, B.J.13
-
26
-
-
20144387627
-
Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
-
Orlowski RZ, Voorhees PM, Garcia RA, Hall MD, Kudrik FJ, Allred T, Johri AR, Jones PE, Ivanova A, Van Deventer HW, Gabriel DA, Shea TC, Mitchell BS, Adams J, Esseltine DL, Trehu EG, Green M, Lehman MJ, Natoli S, Collins JM, Lindley CM, Dees EC 2005 Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 105:3058-3065
-
(2005)
Blood
, vol.105
, pp. 3058-3065
-
-
Orlowski, R.Z.1
Voorhees, P.M.2
Garcia, R.A.3
Hall, M.D.4
Kudrik, F.J.5
Allred, T.6
Johri, A.R.7
Jones, P.E.8
Ivanova, A.9
Van Deventer, H.W.10
Gabriel, D.A.11
Shea, T.C.12
Mitchell, B.S.13
Adams, J.14
Esseltine, D.L.15
Trehu, E.G.16
Green, M.17
Lehman, M.J.18
Natoli, S.19
Collins, J.M.20
Lindley, C.M.21
Dees, E.C.22
more..
|