HIV-1 gp120 Induces Expression of IL-6 through a Nuclear Factor-Kappa B-Dependent Mechanism: Suppression by gp120 Specific Small Interfering RNA

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Shah, Ankit ^a   Verma, Ashish S ^a,e   Patel, Kalpeshkumar H ^a   Noel, Richard ^b   Rivera Amill, Vanessa ^b   Silverstein, Peter S ^a   Chaudhary, Suman ^b,f   Bhat, Hari K ^a   Stamatatos, Leonidas ^c   Singh, Dhirendra P ^d   Buch, Shilpa ^d   Kumar, Anil ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b PONCE SCHOOL OF MEDICINE   (Puerto Rico)

^c SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^e AMITY UNIVERSITY   (India)

^f STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; GLYCOPROTEIN GP 120; I KAPPA B ALPHA; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; SC 514; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; I KAPPA B; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA;

ARTICLE; ASTROCYTE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DRUG EFFECT; DRUG TARGETING; FETUS; FETUS CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; CELL LINE; CYTOLOGY; GENETICS; METABOLISM; PHYSIOLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ASTROCYTES; CELL LINE; FETUS; HIV ENVELOPE PROTEIN GP120; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-6; NF-KAPPA B; RNA, SMALL INTERFERING;

EID: 79959330425     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021261     Document Type: Article

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