메뉴 건너뛰기




Volumn 67, Issue 2, 2012, Pages 139-146

Proteasomal inhibition after injury prevents fibrosis by modulating TGF-β1 signalling

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; BORTEZOMIB; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEASOME; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84856049288     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2011-200717     Document Type: Article
Times cited : (74)

References (39)
  • 1
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • DOI 10.1002/path.2277
    • Wynn TA. Cellular and molecular mechanisms of fibrosis. J Pathol 2008;214:199-210. (Pubitemid 351160157)
    • (2008) Journal of Pathology , vol.214 , Issue.2 , pp. 199-210
    • Wynn, T.A.1
  • 2
    • 33745808765 scopus 로고    scopus 로고
    • Transforming growth factor beta: A central modulator of pulmonary and airway inflammation and fibrosis
    • DOI 10.1513/pats.200601-008AW
    • Sheppard D. Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis. Proc Am Thorac Soc 2006;3:413-17. (Pubitemid 44033355)
    • (2006) Proceedings of the American Thoracic Society , vol.3 , Issue.5 , pp. 413-417
    • Sheppard, D.1
  • 3
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • DOI 10.1038/nature02006
    • Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003;425:577-84. (Pubitemid 37280136)
    • (2003) Nature , vol.425 , Issue.6958 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 7
    • 33644548700 scopus 로고    scopus 로고
    • Proteasome inhibition induces hepatic stellate cell apoptosis
    • Anan A, Baskin-Bey ES, Bronk SF, et al. Proteasome inhibition induces hepatic stellate cell apoptosis. Hepatology 2006;43:335-44.
    • (2006) Hepatology , vol.43 , pp. 335-344
    • Anan, A.1    Baskin-Bey, E.S.2    Bronk, S.F.3
  • 10
    • 2842593814 scopus 로고    scopus 로고
    • Attenuation of renal fibrosis by proteasome inhibition in rat obstructive nephropathy: Possible role of nuclear factor kappaB
    • Tashiro K, Tamada S, Kuwabara N, et al. Attenuation of renal fibrosis by proteasome inhibition in rat obstructive nephropathy: possible role of nuclear factor kappaB. Int J Mol Med 2003;12:587-92.
    • (2003) Int J Mol Med , vol.12 , pp. 587-592
    • Tashiro, K.1    Tamada, S.2    Kuwabara, N.3
  • 13
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer SA, Umesono K, Noonan DJ, et al. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 1992;358:771-4.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3
  • 14
    • 33947124743 scopus 로고    scopus 로고
    • Bronchoalveolar lavage fluid from patients with acute lung injury/acute respiratory distress syndrome induces myofibroblast differentiation
    • DOI 10.1097/01.CCM.0000257254.87984.69, PII 0000324620070300000023
    • Synenki L, Chandel NS, Budinger GR, et al. Bronchoalveolar lavage fluid from patients with acute lung injury/acute respiratory distress syndrome induces myofibroblast differentiation. Crit Care Med 2007;35:842-8. (Pubitemid 46407800)
    • (2007) Critical Care Medicine , vol.35 , Issue.3 , pp. 842-848
    • Synenki, L.1    Chandel, N.S.2    Budinger, G.R.S.3    Donnelly, H.K.4    Topin, J.5    Eisenbart, J.6    Jovanovic, B.7    Jain, M.8
  • 15
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: Minimum information for publication of quantitative real-time PCR experiments
    • Bustin SA, Benes V, Garson JA, et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 2009;55:611-22.
    • (2009) Clin Chem , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3
  • 16
    • 59049090581 scopus 로고    scopus 로고
    • Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution
    • Soberanes S, Urich D, Baker CM, et al. Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution. J Biol Chem 2009;284:2176-86.
    • (2009) J Biol Chem , vol.284 , pp. 2176-2186
    • Soberanes, S.1    Urich, D.2    Baker, C.M.3
  • 17
    • 12944304176 scopus 로고    scopus 로고
    • Active transforming growth factor-beta1 activates the procollagen I promoter in patients with acute lung injury
    • DOI 10.1007/s00134-004-2503-2
    • Budinger GR, Chandel NS, Donnelly HK, et al. Active transforming growth factor-beta1 activates the procollagen I promoter in patients with acute lung injury. Intensive Care Med 2005;31:121-8. (Pubitemid 40174291)
    • (2005) Intensive Care Medicine , vol.31 , Issue.1 , pp. 121-128
    • Budinger, G.R.S.1    Chandel, N.S.2    Donnelly, H.K.3    Eisenbart, J.4    Oberoi, M.5    Jain, M.6
  • 18
    • 70349237004 scopus 로고    scopus 로고
    • Essential roles for early growth response transcription factor Egr-1 in tissue fibrosis and wound healing
    • Wu M, Melichian DS, de la Garza M, et al. essential roles for early growth response transcription factor Egr-1 in tissue fibrosis and wound healing. Am J Pathol 2009;175:1041-55.
    • (2009) Am J Pathol , vol.175 , pp. 1041-1055
    • Wu, M.1    Melichian, D.S.2    De La Garza, M.3
  • 19
    • 79957945650 scopus 로고    scopus 로고
    • Leptin promotes fibroproliferative acute respiratory distress syndrome by inhibiting peroxisome proliferator-activated receptor-{gamma}
    • Jain M, Budinger GRS, Lo A, et al. Leptin promotes fibroproliferative acute respiratory distress syndrome by inhibiting peroxisome proliferator-activated receptor-{gamma}. Am J Respir Crit Care Med 2011;183:1490-8.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1490-1498
    • Jain, M.1    Budinger, G.R.S.2    Lo, A.3
  • 21
    • 78349281192 scopus 로고    scopus 로고
    • PPARγ downregulation by TGFβ in fibroblast and impaired expression and function in systemic sclerosis: A novel mechanism for progressive fibrogenesis
    • Wei J, Ghosh AK, Sargent JL, et al. PPARγ downregulation by TGFβ in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis. PLoS One 2010;5:e13778.
    • (2010) PLoS One , vol.5
    • Wei, J.1    Ghosh, A.K.2    Sargent, J.L.3
  • 22
    • 53349129568 scopus 로고    scopus 로고
    • In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis
    • Fineschi S, Bongiovanni M, Donati Y, et al. In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis. Am J Respir Cell Mol Biol 2008;39:458-65.
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 458-465
    • Fineschi, S.1    Bongiovanni, M.2    Donati, Y.3
  • 24
    • 1842733168 scopus 로고    scopus 로고
    • Disruption of Transforming Growth Factor beta Signaling and Profibrotic Responses in Normal Skin Fibroblasts by Peroxisome Proliferator-Activated Receptor gamma
    • DOI 10.1002/art.20104
    • Ghosh AK, Bhattacharyya S, Lakos G, et al. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma. Arthritis Rheum 2004;50:1305-18. (Pubitemid 38480842)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.4 , pp. 1305-1318
    • Ghosh, A.K.1    Bhattacharyya, S.2    Lakos, G.3    Chen, S.-J.4    Mori, Y.5    Varga, J.6
  • 25
    • 70349331686 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-{gamma} abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator
    • Ghosh AK, Bhattacharyya S, Wei J, et al. Peroxisome proliferator- activated receptor-{gamma} abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator. FASEB J 2009;23:2968-77.
    • (2009) FASEB J , vol.23 , pp. 2968-2977
    • Ghosh, A.K.1    Bhattacharyya, S.2    Wei, J.3
  • 26
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARgamma
    • Tontonoz P, Spiegelman BM. Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem 2008;77:289-312.
    • (2008) Annu Rev Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 28
    • 78649681350 scopus 로고    scopus 로고
    • Efficacy and safety of once-weekly bortezomib in multiple myeloma patients
    • Bringhen S, Larocca A, Rossi D, et al. Efficacy and safety of once-weekly bortezomib in multiple myeloma patients. Blood 2010;116:4745-53.
    • (2010) Blood , vol.116 , pp. 4745-4753
    • Bringhen, S.1    Larocca, A.2    Rossi, D.3
  • 29
    • 0037331234 scopus 로고    scopus 로고
    • 1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching
    • Chambers RC, Leoni P, Kaminski N, et al. Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching. Am J Pathol 2003;162:533-46. (Pubitemid 36267860)
    • (2003) American Journal of Pathology , vol.162 , Issue.2 , pp. 533-546
    • Chambers, R.C.1    Leoni, P.2    Kaminski, N.3    Laurent, G.J.4    Heller, R.A.5
  • 30
    • 45849149234 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis
    • Milam JE, Keshamouni VG, Phan SH, et al. PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 2008;294:L891-901.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294
    • Milam, J.E.1    Keshamouni, V.G.2    Phan, S.H.3
  • 32
    • 33645292701 scopus 로고    scopus 로고
    • Severe pulmonary complications in Japanese patients after bortezomib treatment for refractory multiple myeloma
    • Miyakoshi S, Kami M, Yuji K, et al. Severe pulmonary complications in Japanese patients after bortezomib treatment for refractory multiple myeloma. Blood 2006;107:3492-4.
    • (2006) Blood , vol.107 , pp. 3492-3494
    • Miyakoshi, S.1    Kami, M.2    Yuji, K.3
  • 33
    • 33751355500 scopus 로고    scopus 로고
    • Severe pulmonary complications in African-American patient after bortezomib therapy
    • DOI 10.1097/01.mjt.0000245224.20913.0d, PII 0004539120061100000016
    • Ohri A, Arena FP. Severe pulmonary complications in African-American patient after bortezomib therapy. Am J Ther 2006;13:553-5. (Pubitemid 44813688)
    • (2006) American Journal of Therapeutics , vol.13 , Issue.6 , pp. 553-555
    • Ohri, A.1    Arena, F.P.2
  • 34
    • 33746610136 scopus 로고    scopus 로고
    • Severe pulmonary complication after bortezomib treatment for multiple myeloma [8]
    • DOI 10.1182/blood-2006-03-011494
    • Boyer JE, Batra RB, Ascensao JL, et al. Severe pulmonary complication after bortezomib treatment for multiple myeloma. Blood 2006;108:1113. (Pubitemid 44154659)
    • (2006) Blood , vol.108 , Issue.3 , pp. 1113
    • Boyer, J.E.1    Batra, R.B.2    Ascensao, J.L.3    Schechter, G.P.4
  • 35
    • 57449117694 scopus 로고    scopus 로고
    • Cooperative relationship between pharmaceutical companies, academia, and media explains sharp decrease in frequency of pulmonary complications after bortezomib in Japan
    • Narimatsu H, Hori A, Matsumura T, et al. Cooperative relationship between pharmaceutical companies, academia, and media explains sharp decrease in frequency of pulmonary complications after bortezomib in Japan. J Clin Oncol 2008;26:5820-3.
    • (2008) J Clin Oncol , vol.26 , pp. 5820-5823
    • Narimatsu, H.1    Hori, A.2    Matsumura, T.3
  • 38
    • 77749324295 scopus 로고    scopus 로고
    • Imatinib treatment for idiopathic pulmonary fibrosis: Randomized placebo-controlled trial results
    • Daniels CE, Lasky JA, Limper AH, et al. Imatinib treatment for idiopathic pulmonary fibrosis: randomized placebo-controlled trial results. Am J Respir Crit Care Med 2010;181:604-10.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 604-610
    • Daniels, C.E.1    Lasky, J.A.2    Limper, A.H.3
  • 39
    • 77749322716 scopus 로고    scopus 로고
    • Challenges in translating preclinical studies to effective drug therapies in idiopathic pulmonary fibrosis
    • Thannickal VJ, Roman J. Challenges in translating preclinical studies to effective drug therapies in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2010;181:532-3.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 532-533
    • Thannickal, V.J.1    Roman, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.