메뉴 건너뛰기




Volumn 2, Issue 1, 2014, Pages

Integrated multi-cohort transcriptional meta-analysis of neurodegenerative diseases

Author keywords

Aging; Biomarkers; Meta analysis; Neurodegeneration; Therapeutic targets; Transcriptome

Indexed keywords

TRANSCRIPTION FACTOR;

EID: 84965089714     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-014-0093-y     Document Type: Review
Times cited : (84)

References (124)
  • 1
    • 84879125617 scopus 로고    scopus 로고
    • The coming crisis: obtaining care for the growing burden of neurodegenerative conditions
    • Dorsey ER, George BP, Leff B, Willis AW: The coming crisis: obtaining care for the growing burden of neurodegenerative conditions. Neurology 2013, 80: 1989-1996. doi:10.1212/WNL.0b013e318293e2ce
    • (2013) Neurology , vol.80 , pp. 1989-1996
    • Dorsey, E.R.1    George, B.P.2    Leff, B.3    Willis, A.W.4
  • 2
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
    • Zlokovic BV: Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat Rev Neurosci 2011, 12: 723-738. doi:10.1038/nrn3114
    • (2011) Nat Rev Neurosci , vol.12 , pp. 723-738
    • Zlokovic, B.V.1
  • 3
    • 84871919598 scopus 로고    scopus 로고
    • Excitotoxicity: bridge to various triggers in neurodegenerative disorders
    • Mehta A, Prabhakar M, Kumar P, Deshmukh R, Sharma PL: Excitotoxicity: bridge to various triggers in neurodegenerative disorders. Eur J Pharmacol 2013, 698: 6-18. doi:10.1016/j.ejphar.2012.10.032
    • (2013) Eur J Pharmacol , vol.698 , pp. 6-18
    • Mehta, A.1    Prabhakar, M.2    Kumar, P.3    Deshmukh, R.4    Sharma, P.L.5
  • 4
    • 65949121134 scopus 로고    scopus 로고
    • Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options
    • Uttara B, Singh AV, Zamboni P, Mahajan RT: Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr Neuropharmacol 2009, 7: 65-74. doi:10.2174/157015909787602823
    • (2009) Curr Neuropharmacol , vol.7 , pp. 65-74
    • Uttara, B.1    Singh, A.V.2    Zamboni, P.3    Mahajan, R.T.4
  • 5
    • 77955912778 scopus 로고    scopus 로고
    • Traumatic brain injury: a disease process, not an event
    • Masel BE, DeWitt DS: Traumatic brain injury: a disease process, not an event. J Neurotrauma 2010, 27: 1529-1540. doi:10.1089/neu.2010.1358
    • (2010) J Neurotrauma , vol.27 , pp. 1529-1540
    • Masel, B.E.1    DeWitt, D.S.2
  • 6
    • 61649106707 scopus 로고    scopus 로고
    • Environmental-induced oxidative stress in neurodegenerative disorders and aging
    • Migliore L, Coppedé F: Environmental-induced oxidative stress in neurodegenerative disorders and aging. Mutat Res 2009, 674: 73-84. doi:10.1016/j.mrgentox.2008.09.013
    • (2009) Mutat Res , vol.674 , pp. 73-84
    • Migliore, L.1    Coppedé, F.2
  • 7
    • 77951096150 scopus 로고    scopus 로고
    • Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
    • Chen H, Chan DC: Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases. Hum Mol Genet 2009, 18: R169-R176. doi:10.1093/hmg/ddp326
    • (2009) Hum Mol Genet , vol.18 , pp. R169-R176
    • Chen, H.1    Chan, D.C.2
  • 8
    • 77953890823 scopus 로고    scopus 로고
    • TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
    • Lagier-Tourenne C, Polymenidou M, Cleveland DW: TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum Mol Genet 2010, 19: R46-R64. doi:10.1093/hmg/ddq137
    • (2010) Hum Mol Genet , vol.19 , pp. R46-R64
    • Lagier-Tourenne, C.1    Polymenidou, M.2    Cleveland, D.W.3
  • 9
    • 77954116814 scopus 로고    scopus 로고
    • Autophagy gone awry in neurodegenerative diseases
    • Wong E, Cuervo AM: Autophagy gone awry in neurodegenerative diseases. Nat Neurosci 2010, 13: 805-811. doi:10.1038/nn.2575
    • (2010) Nat Neurosci , vol.13 , pp. 805-811
    • Wong, E.1    Cuervo, A.M.2
  • 12
    • 84980053612 scopus 로고    scopus 로고
    • Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders
    • Ramanan VK, Saykin AJ: Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders. Am J Neurodegener Dis 2013, 2: 145-175.
    • (2013) Am J Neurodegener Dis , vol.2 , pp. 145-175
    • Ramanan, V.K.1    Saykin, A.J.2
  • 13
    • 33745268155 scopus 로고    scopus 로고
    • Transcriptional changes in multiple system atrophy and Parkinson's disease putamen
    • Vogt IR, Lees AJ, Evert BO, Klockgether T, Bonin M, Wüllner U: Transcriptional changes in multiple system atrophy and Parkinson's disease putamen. Exp Neurol 2006, 199: 465-478. doi:10.1016/j.expneurol.2006.01.008
    • (2006) Exp Neurol , vol.199 , pp. 465-478
    • Vogt, I.R.1    Lees, A.J.2    Evert, B.O.3    Klockgether, T.4    Bonin, M.5    Wüllner, U.6
  • 15
    • 80052099172 scopus 로고    scopus 로고
    • Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease
    • Blalock EM, Buechel HM, Popovic J, Geddes JW, Landfield PW: Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease. J Chem Neuroanat 2011, 42: 118-126. doi:10.1016/j.jchemneu.2011.06.007
    • (2011) J Chem Neuroanat , vol.42 , pp. 118-126
    • Blalock, E.M.1    Buechel, H.M.2    Popovic, J.3    Geddes, J.W.4    Landfield, P.W.5
  • 17
    • 3042694117 scopus 로고    scopus 로고
    • Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression
    • Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM: Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression. Proc Natl Acad Sci U S A 2004, 101: 9309-9314. doi:10.1073/pnas.0401994101
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 9309-9314
    • Rhodes, D.R.1    Yu, J.2    Shanker, K.3    Deshpande, N.4    Varambally, R.5    Ghosh, D.6    Barrette, T.7    Pandey, A.8    Chinnaiyan, A.M.9
  • 18
    • 15944395145 scopus 로고    scopus 로고
    • Insights into host responses against pathogens from transcriptional profiling
    • Jenner RG, Young R: Insights into host responses against pathogens from transcriptional profiling. Nat Rev Microbiol 2005, 3: 281-294. doi:10.1038/nrmicro1126
    • (2005) Nat Rev Microbiol , vol.3 , pp. 281-294
    • Jenner, R.G.1    Young, R.2
  • 21
    • 84889095368 scopus 로고    scopus 로고
    • pheatmap: Pretty Heatmaps
    • Kolde R: pheatmap: Pretty Heatmaps.., [ http://cran.r-project.org/web/packages/pheatmap/index.html ]
    • Kolde, R.1
  • 22
    • 33847209892 scopus 로고    scopus 로고
    • Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis
    • Lederer CW, Torrisi A, Pantelidou M, Santama N, Cavallaro S: Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. BMC Genomics 2007, 8: 26. doi:10.1186/1471-2164-8-26
    • (2007) BMC Genomics , vol.8 , pp. 26
    • Lederer, C.W.1    Torrisi, A.2    Pantelidou, M.3    Santama, N.4    Cavallaro, S.5
  • 27
    • 23044502947 scopus 로고    scopus 로고
    • Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms
    • Zhang Y, James M, Middleton FA, Davis RL: Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. Am J Med Genet B Neuropsychiatr Genet 2005, 137B: 5-16. doi:10.1002/ajmg.b.30195
    • (2005) Am J Med Genet B Neuropsychiatr Genet , vol.137B , pp. 5-16
    • Zhang, Y.1    James, M.2    Middleton, F.A.3    Davis, R.L.4
  • 28
    • 84878007793 scopus 로고    scopus 로고
    • Genes and pathways underlying regional and cell type changes in Alzheimer's disease
    • Miller JA, Woltjer RL, Goodenbour JM, Horvath S, Geschwind DH: Genes and pathways underlying regional and cell type changes in Alzheimer's disease. Genome Med 2013, 5: 48. doi:10.1186/gm452
    • (2013) Genome Med , vol.5 , pp. 48
    • Miller, J.A.1    Woltjer, R.L.2    Goodenbour, J.M.3    Horvath, S.4    Geschwind, D.H.5
  • 31
    • 19944428747 scopus 로고    scopus 로고
    • Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes
    • Grünblatt E, Mandel S, Jacob-Hirsch J, Zeligson S, Amariglo N, Rechavi G, Li J, Ravid R, Roggendorf W, Riederer P, Youdim MBH: Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes. J Neural Transm 2004, 111: 1543-1573. doi:10.1007/s00702-004-0212-1
    • (2004) J Neural Transm , vol.111 , pp. 1543-1573
    • Grünblatt, E.1    Mandel, S.2    Jacob-Hirsch, J.3    Zeligson, S.4    Amariglo, N.5    Rechavi, G.6    Li, J.7    Ravid, R.8    Roggendorf, W.9    Riederer, P.10    Youdim, M.B.H.11
  • 33
    • 33644658492 scopus 로고    scopus 로고
    • Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease
    • Moran LB, Duke DC, Deprez M, Dexter DT, Pearce RKB, Graeber MB: Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease. Neurogenetics 2006, 7: 1-11. doi:10.1007/s10048-005-0020-2
    • (2006) Neurogenetics , vol.7 , pp. 1-11
    • Moran, L.B.1    Duke, D.C.2    Deprez, M.3    Dexter, D.T.4    Pearce, R.K.B.5    Graeber, M.B.6
  • 35
    • 1242341923 scopus 로고    scopus 로고
    • Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses
    • Blalock EM, Geddes JW, Chen KC, Porter NM, Markesbery WR, Landfield PW: Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc Natl Acad Sci U S A 2004, 101: 2173-2178. doi:10.1073/pnas.0308512100
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2173-2178
    • Blalock, E.M.1    Geddes, J.W.2    Chen, K.C.3    Porter, N.M.4    Markesbery, W.R.5    Landfield, P.W.6
  • 36
    • 69949083603 scopus 로고    scopus 로고
    • Comprehensive mRNA expression profiling distinguishes tauopathies and identifies shared molecular pathways
    • Bronner IF, Bochdanovits Z, Rizzu P, Kamphorst W, Ravid R, van Swieten JC, Heutink P: Comprehensive mRNA expression profiling distinguishes tauopathies and identifies shared molecular pathways. PLoS One 2009, 4: e6826. doi:10.1371/journal.pone.0006826
    • (2009) PLoS One , vol.4
    • Bronner, I.F.1    Bochdanovits, Z.2    Rizzu, P.3    Kamphorst, W.4    Ravid, R.5    van Swieten, J.C.6    Heutink, P.7
  • 38
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y: Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B 1995, 57: 289-300. doi:10.2307/2346101
    • (1995) J R Stat Soc Ser B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 40
    • 77749296886 scopus 로고    scopus 로고
    • ggplot2: Elegant Graphics for Data Analysis
    • Springer, New York;
    • Wickham H: ggplot2: Elegant Graphics for Data Analysis. Springer, New York; 2009.
    • (2009)
    • Wickham, H.1
  • 42
    • 80054761009 scopus 로고    scopus 로고
    • Network Biology.
    • Merico D, Isserlin R, Bader GD: Network Biology.. 2011, 781: 257-277. doi:10.1007/978-1-61779-276-2
    • (2011) , vol.781 , pp. 257-277
    • Merico, D.1    Isserlin, R.2    Bader, G.D.3
  • 45
    • 3042631024 scopus 로고    scopus 로고
    • Gene regulation and DNA damage in the ageing human brain
    • Lu T, Pan Y, Kao S-Y, Li C, Kohane I, Chan J, Yankner BA: Gene regulation and DNA damage in the ageing human brain. Nature 2004, 429: 883-891. doi:10.1038/nature02661
    • (2004) Nature , vol.429 , pp. 883-891
    • Lu, T.1    Pan, Y.2    Kao, S.-Y.3    Li, C.4    Kohane, I.5    Chan, J.6    Yankner, B.A.7
  • 48
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang DW, Sherman BT, Lempicki R: Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009, 4: 44-57. doi:10.1038/nprot.2008.211
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.3
  • 56
    • 84880569366 scopus 로고    scopus 로고
    • Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool
    • Auerbach RK, Chen B, Butte AJ: Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool. Bioinformatics 2013, 29: 1922-1924. doi:10.1093/bioinformatics/btt316
    • (2013) Bioinformatics , vol.29 , pp. 1922-1924
    • Auerbach, R.K.1    Chen, B.2    Butte, A.J.3
  • 57
    • 84899583984 scopus 로고    scopus 로고
    • CCAAT-enhancer binding protein-β expression and elevation in Alzheimer's disease and microglial cell cultures
    • Strohmeyer R, Shelton J, Lougheed C, Breitkopf T: CCAAT-enhancer binding protein-β expression and elevation in Alzheimer's disease and microglial cell cultures. PLoS One 2014, 9: e86617. doi:10.1371/journal.pone.0086617
    • (2014) PLoS One , vol.9
    • Strohmeyer, R.1    Shelton, J.2    Lougheed, C.3    Breitkopf, T.4
  • 58
    • 84863501943 scopus 로고    scopus 로고
    • C/EBPβ expression in activated microglia in amyotrophic lateral sclerosis
    • Valente T, Mancera P, Tusell JM, Serratosa J, Saura J: C/EBPβ expression in activated microglia in amyotrophic lateral sclerosis. Neurobiol Aging 2012, 33: 2186-2199. doi:10.1016/j.neurobiolaging.2011.09.019
    • (2012) Neurobiol Aging , vol.33 , pp. 2186-2199
    • Valente, T.1    Mancera, P.2    Tusell, J.M.3    Serratosa, J.4    Saura, J.5
  • 59
    • 84857781607 scopus 로고    scopus 로고
    • Cdk5: a multifaceted kinase in neurodegenerative diseases
    • Cheung ZH, Ip NY: Cdk5: a multifaceted kinase in neurodegenerative diseases. Trends Cell Biol 2012, 22: 169-175. doi:10.1016/j.tcb.2011.11.003
    • (2012) Trends Cell Biol , vol.22 , pp. 169-175
    • Cheung, Z.H.1    Ip, N.Y.2
  • 61
    • 84875416419 scopus 로고    scopus 로고
    • Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms
    • Huang C, Hatzi K, Melnick A: Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms. Nat Immunol 2013, 14: 380-388. doi:10.1038/ni.2543
    • (2013) Nat Immunol , vol.14 , pp. 380-388
    • Huang, C.1    Hatzi, K.2    Melnick, A.3
  • 62
    • 46249090513 scopus 로고    scopus 로고
    • Colony-stimulating factors in inflammation and autoimmunity
    • Hamilton JA: Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol 2008, 8: 533-544. doi:10.1038/nri2356
    • (2008) Nat Rev Immunol , vol.8 , pp. 533-544
    • Hamilton, J.A.1
  • 63
    • 0034596949 scopus 로고    scopus 로고
    • Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
    • Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD: Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J Exp Med 2000, 192: 1075-1080.
    • (2000) J Exp Med , vol.192 , pp. 1075-1080
    • Izikson, L.1    Klein, R.S.2    Charo, I.F.3    Weiner, H.L.4    Luster, A.D.5
  • 64
    • 0141738762 scopus 로고    scopus 로고
    • Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C
    • Fehrenbacher JC, Taylor CP, Vasko MR: Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C. Pain 2003, 105: 133-141.
    • (2003) Pain , vol.105 , pp. 133-141
    • Fehrenbacher, J.C.1    Taylor, C.P.2    Vasko, M.R.3
  • 65
    • 49349101732 scopus 로고    scopus 로고
    • Transcription factor Sp1 dysregulation in Alzheimer's disease
    • Citron B, Dennis JS, Zeitlin RS, Echeverria V: Transcription factor Sp1 dysregulation in Alzheimer's disease. J Neurosci Res 2008, 86: 2499-2504. doi:10.1002/jnr.21695
    • (2008) J Neurosci Res , vol.86 , pp. 2499-2504
    • Citron, B.1    Dennis, J.S.2    Zeitlin, R.S.3    Echeverria, V.4
  • 66
    • 0037868957 scopus 로고    scopus 로고
    • Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons
    • Ryu H, Lee J, Zaman K, Kubilis J, Ferrante RJ, Ross BD, Neve R, Ratan RR: Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons. J Neurosci 2003, 23: 3597-3606.
    • (2003) J Neurosci , vol.23 , pp. 3597-3606
    • Ryu, H.1    Lee, J.2    Zaman, K.3    Kubilis, J.4    Ferrante, R.J.5    Ross, B.D.6    Neve, R.7    Ratan, R.R.8
  • 67
    • 0033817466 scopus 로고    scopus 로고
    • Tau promoter confers neuronal specificity and binds Sp1 and AP-2
    • Heicklen-Klein A, Ginzburg I: Tau promoter confers neuronal specificity and binds Sp1 and AP-2. J Neurochem 2000, 75: 1408-1418.
    • (2000) J Neurochem , vol.75 , pp. 1408-1418
    • Heicklen-Klein, A.1    Ginzburg, I.2
  • 68
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW: From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 2008, 9: 46-56. doi:10.1038/nrn2297
    • (2008) Nat Rev Neurosci , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 69
    • 84855610801 scopus 로고    scopus 로고
    • Eph receptors at synapses: implications in neurodegenerative diseases
    • Chen Y, Fu AKY, Ip NY: Eph receptors at synapses: implications in neurodegenerative diseases. Cell Signal 2012, 24: 606-611. doi:10.1016/j.cellsig.2011.11.016
    • (2012) Cell Signal , vol.24 , pp. 606-611
    • Chen, Y.1    Fu, A.K.Y.2    Ip, N.Y.3
  • 70
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin MT, Beal MF: Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006, 443: 787-795. doi:10.1038/nature05292
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 71
    • 84891372071 scopus 로고    scopus 로고
    • A role for the neurexin-neuroligin complex in Alzheimer's disease
    • Sindi I, Tannenberg RK, Dodd PR: A role for the neurexin-neuroligin complex in Alzheimer's disease. Neurobiol Aging 2014, 35: 746-756. doi:10.1016/j.neurobiolaging.2013.09.032
    • (2014) Neurobiol Aging , vol.35 , pp. 746-756
    • Sindi, I.1    Tannenberg, R.K.2    Dodd, P.R.3
  • 72
    • 84876741388 scopus 로고    scopus 로고
    • Neurotransmitters and microglial-mediated neuroinflammation
    • Lee M: Neurotransmitters and microglial-mediated neuroinflammation. Curr Protein Pept Sci 2013, 14: 21-32.
    • (2013) Curr Protein Pept Sci , vol.14 , pp. 21-32
    • Lee, M.1
  • 73
    • 84890146490 scopus 로고    scopus 로고
    • Proteostasis and neurodegeneration: the roles of proteasomal degradation and autophagy
    • Tanaka K, Matsuda N: Proteostasis and neurodegeneration: the roles of proteasomal degradation and autophagy. Biochim Biophys Acta 2014, 1843: 197-204. doi:10.1016/j.bbamcr.2013.03.012
    • (2014) Biochim Biophys Acta , vol.1843 , pp. 197-204
    • Tanaka, K.1    Matsuda, N.2
  • 76
    • 62849102088 scopus 로고    scopus 로고
    • Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis
    • Kashiwaya K, Hosokawa M, Eguchi H, Ohigashi H, Ishikawa O, Shinomura Y, Nakamura Y, Nakagawa H: Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis. Cancer Sci 2009, 100: 457-464. doi:10.1111/j.1349-7006.2008.01058.x
    • (2009) Cancer Sci , vol.100 , pp. 457-464
    • Kashiwaya, K.1    Hosokawa, M.2    Eguchi, H.3    Ohigashi, H.4    Ishikawa, O.5    Shinomura, Y.6    Nakamura, Y.7    Nakagawa, H.8
  • 77
    • 84872001053 scopus 로고    scopus 로고
    • Transglutaminase 2 interaction with small heat shock proteins mediate cell survival upon excitotoxic stress
    • Caccamo D, Condello S, Ferlazzo N, Currò M, Griffin M, Ientile R: Transglutaminase 2 interaction with small heat shock proteins mediate cell survival upon excitotoxic stress. Amino Acids 2013, 44: 151-159. doi:10.1007/s00726-011-1083-z
    • (2013) Amino Acids , vol.44 , pp. 151-159
    • Caccamo, D.1    Condello, S.2    Ferlazzo, N.3    Curròò, M.4    Griffin, M.5    Ientile, R.6
  • 78
    • 0032533843 scopus 로고    scopus 로고
    • Characterization of alkaline phosphatase genes expressed in seminoma by cDNA cloning
    • Shigenari A, Ando A, Baba T, Yamamoto T, Katsuoka Y, Inoko H: Characterization of alkaline phosphatase genes expressed in seminoma by cDNA cloning. Cancer Res 1998, 58: 5079-5082.
    • (1998) Cancer Res , vol.58 , pp. 5079-5082
    • Shigenari, A.1    Ando, A.2    Baba, T.3    Yamamoto, T.4    Katsuoka, Y.5    Inoko, H.6
  • 79
    • 84858193852 scopus 로고    scopus 로고
    • Cap-Gly proteins at microtubule plus ends: is EB1 detyrosination involved?
    • Bosson A, Soleilhac J-M, Valiron O, Job D, Andrieux A, Moutin M-J: Cap-Gly proteins at microtubule plus ends: is EB1 detyrosination involved? PLoS One 2012, 7: e33490. doi:10.1371/journal.pone.0033490
    • (2012) PLoS One , vol.7
    • Bosson, A.1    Soleilhac, J.-M.2    Valiron, O.3    Job, D.4    Andrieux, A.5    Moutin, M.-J.6
  • 82
    • 0035055799 scopus 로고    scopus 로고
    • Protein 4.1 in forebrain postsynaptic density preparations: enrichment of 4.1 gene products and detection of 4.1R binding proteins
    • Scott C, Keating L, Bellamy M, Baines AJ: Protein 4.1 in forebrain postsynaptic density preparations: enrichment of 4.1 gene products and detection of 4.1R binding proteins. Eur J Biochem 2001, 268: 1084-1094.
    • (2001) Eur J Biochem , vol.268 , pp. 1084-1094
    • Scott, C.1    Keating, L.2    Bellamy, M.3    Baines, A.J.4
  • 83
    • 0033529498 scopus 로고    scopus 로고
    • Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3
    • Hong H, Yang L, Stallcup MR: Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3. J Biol Chem 1999, 274: 22618-22626.
    • (1999) J Biol Chem , vol.274 , pp. 22618-22626
    • Hong, H.1    Yang, L.2    Stallcup, M.R.3
  • 84
    • 0035892242 scopus 로고    scopus 로고
    • Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release
    • Hu H, Shao LR, Chavoshy S, Gu N, Trieb M, Behrens R, Laake P, Pongs O, Knaus HG, Ottersen OP, Storm JF: Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release. J Neurosci 2001, 21: 9585-9597.
    • (2001) J Neurosci , vol.21 , pp. 9585-9597
    • Hu, H.1    Shao, L.R.2    Chavoshy, S.3    Gu, N.4    Trieb, M.5    Behrens, R.6    Laake, P.7    Pongs, O.8    Knaus, H.G.9    Ottersen, O.P.10    Storm, J.F.11
  • 85
    • 0032806355 scopus 로고    scopus 로고
    • Increased microglial activation and protein nitration in white matter of the aging monkey
    • Sloane JA, Hollander W, Moss MB, Rosene DL, Abraham CR: Increased microglial activation and protein nitration in white matter of the aging monkey. Neurobiol Aging 1999, 20: 395-405.
    • (1999) Neurobiol Aging , vol.20 , pp. 395-405
    • Sloane, J.A.1    Hollander, W.2    Moss, M.B.3    Rosene, D.L.4    Abraham, C.R.5
  • 86
    • 0032080230 scopus 로고    scopus 로고
    • Reversal of age-related alterations in synaptic plasticity by blockade of L-type Ca2+ channels
    • Norris CM, Halpain S, Foster TC: Reversal of age-related alterations in synaptic plasticity by blockade of L-type Ca2+ channels. J Neurosci 1998, 18: 3171-3179.
    • (1998) J Neurosci , vol.18 , pp. 3171-3179
    • Norris, C.M.1    Halpain, S.2    Foster, T.C.3
  • 89
    • 33751191715 scopus 로고    scopus 로고
    • Taking down the unindicted co-conspirators of amyloid beta-peptide-mediated neuronal death: shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors
    • Lahiri DK, Ge Y-W, Rogers JT, Sambamurti K, Greig NH, Maloney B: Taking down the unindicted co-conspirators of amyloid beta-peptide-mediated neuronal death: shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors. Curr Alzheimer Res 2006, 3: 475-483.
    • (2006) Curr Alzheimer Res , vol.3 , pp. 475-483
    • Lahiri, D.K.1    Ge, Y.-W.2    Rogers, J.T.3    Sambamurti, K.4    Greig, N.H.5    Maloney, B.6
  • 91
    • 84895822432 scopus 로고    scopus 로고
    • Yin Yang 1 Is a Repressor of Glutamate Transporter EAAT2, and It Mediates Manganese-Induced Decrease of EAAT2 Expression in Astrocytes
    • Karki P, Webb A, Smith K, Johnson J, Lee K, Son D-S, Aschner M, Lee E: Yin Yang 1 Is a Repressor of Glutamate Transporter EAAT2, and It Mediates Manganese-Induced Decrease of EAAT2 Expression in Astrocytes. Mol Cell Biol 2014, 34: 1280-1289. doi:10.1128/MCB.01176-13
    • (2014) Mol Cell Biol , vol.34 , pp. 1280-1289
    • Karki, P.1    Webb, A.2    Smith, K.3    Johnson, J.4    Lee, K.5    Son, D.-S.6    Aschner, M.7    Lee, E.8
  • 92
    • 36749081539 scopus 로고    scopus 로고
    • mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex
    • Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P: mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature 2007, 450: 736-740. doi:10.1038/nature06322
    • (2007) Nature , vol.450 , pp. 736-740
    • Cunningham, J.T.1    Rodgers, J.T.2    Arlow, D.H.3    Vazquez, F.4    Mootha, V.K.5    Puigserver, P.6
  • 94
    • 84867397417 scopus 로고    scopus 로고
    • An asymmetrically localized Staufen2-dependent RNA complex regulates maintenance of mammalian neural stem cells
    • Vessey JP, Amadei G, Burns SE, Kiebler MA, Kaplan DR, Miller FD: An asymmetrically localized Staufen2-dependent RNA complex regulates maintenance of mammalian neural stem cells. Cell Stem Cell 2012, 11: 517-528. doi:10.1016/j.stem.2012.06.010
    • (2012) Cell Stem Cell , vol.11 , pp. 517-528
    • Vessey, J.P.1    Amadei, G.2    Burns, S.E.3    Kiebler, M.A.4    Kaplan, D.R.5    Miller, F.D.6
  • 96
    • 31144466836 scopus 로고    scopus 로고
    • Low mRNA levels of RGS4 splice variants in Alzheimer's disease: association between a rare haplotype and decreased mRNA expression
    • Emilsson L, Saetre P, Jazin E: Low mRNA levels of RGS4 splice variants in Alzheimer's disease: association between a rare haplotype and decreased mRNA expression. Synapse 2006, 59: 173-176. doi:10.1002/syn.20226
    • (2006) Synapse , vol.59 , pp. 173-176
    • Emilsson, L.1    Saetre, P.2    Jazin, E.3
  • 97
    • 55749107270 scopus 로고    scopus 로고
    • Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry
    • Runne H, Régulier E, Kuhn A, Zala D, Gokce O, Perrin V, Sick B, Aebischer P, Déglon N, Luthi-Carter R: Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry. J Neurosci 2008, 28: 9723-9731. doi:10.1523/JNEUROSCI.3044-08.2008
    • (2008) J Neurosci , vol.28 , pp. 9723-9731
    • Runne, H.1    Régulier, E.2    Kuhn, A.3    Zala, D.4    Gokce, O.5    Perrin, V.6    Sick, B.7    Aebischer, P.8    Déglon, N.9    Luthi-Carter, R.10
  • 98
    • 0035061298 scopus 로고    scopus 로고
    • Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia
    • Mirnics K, Middleton FA, Stanwood GD, Lewis DA, Levitt P: Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia. Mol Psychiatry 2001, 6: 293-301. doi:10.1038/sj.mp.4000866
    • (2001) Mol Psychiatry , vol.6 , pp. 293-301
    • Mirnics, K.1    Middleton, F.A.2    Stanwood, G.D.3    Lewis, D.A.4    Levitt, P.5
  • 100
    • 52049096152 scopus 로고    scopus 로고
    • Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons
    • Hasegawa K, Yoshikawa K: Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons. J Neurosci 2008, 28: 8772-8784. doi:10.1523/JNEUROSCI.3052-08.2008
    • (2008) J Neurosci , vol.28 , pp. 8772-8784
    • Hasegawa, K.1    Yoshikawa, K.2
  • 101
    • 85005894245 scopus 로고    scopus 로고
    • Cell cycle regulation promotes survival of dopaminergic neurons in experimental Parkinson's disease [abstract]
    • Yasuda T, Yoshikawa K, Przedborski S, Mizuno Y, Mochizuki H: Cell cycle regulation promotes survival of dopaminergic neurons in experimental Parkinson's disease [abstract]. Mov Disord 2012, 27: 1523.
    • (2012) Mov Disord , vol.27 , pp. 1523
    • Yasuda, T.1    Yoshikawa, K.2    Przedborski, S.3    Mizuno, Y.4    Mochizuki, H.5
  • 102
    • 34548202642 scopus 로고    scopus 로고
    • Nap1l2 promotes histone acetylation activity during neuronal differentiation
    • Attia M, Rachez C, De Pauw A, Avner P, Rogner UC: Nap1l2 promotes histone acetylation activity during neuronal differentiation. Mol Cell Biol 2007, 27: 6093-6102. doi:10.1128/MCB.00789-07
    • (2007) Mol Cell Biol , vol.27 , pp. 6093-6102
    • Attia, M.1    Rachez, C.2    De Pauw, A.3    Avner, P.4    Rogner, U.C.5
  • 104
    • 84896719812 scopus 로고    scopus 로고
    • Tau promotes neurodegeneration through global chromatin relaxation
    • Frost B, Hemberg M, Lewis J, Feany MB: Tau promotes neurodegeneration through global chromatin relaxation. Nat Neurosci 2014, 17: 357-366. doi:10.1038/nn.3639
    • (2014) Nat Neurosci , vol.17 , pp. 357-366
    • Frost, B.1    Hemberg, M.2    Lewis, J.3    Feany, M.B.4
  • 105
    • 0018729370 scopus 로고
    • Altered chromatin conformation in Alzheimer's disease
    • Crapper DR, Quittkat S, de Boni U: Altered chromatin conformation in Alzheimer's disease. Brain 1979, 102: 483-495.
    • (1979) Brain , vol.102 , pp. 483-495
    • Crapper, D.R.1    Quittkat, S.2    de Boni, U.3
  • 106
    • 84875634684 scopus 로고    scopus 로고
    • Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-ΚB signaling in neurons
    • König H-G, Fenner BJ, Byrne JC, Schwamborn RF, Bernas T, Jefferies CA, Prehn JHM: Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-ΚB signaling in neurons. J Cell Sci 2012, 125: 6058-6070. doi:10.1242/jcs.111880
    • (2012) J Cell Sci , vol.125 , pp. 6058-6070
    • König, H.-G.1    Fenner, B.J.2    Byrne, J.C.3    Schwamborn, R.F.4    Bernas, T.5    Jefferies, C.A.6    Prehn, J.H.M.7
  • 107
    • 84862669298 scopus 로고    scopus 로고
    • Fibroblast growth factor 13 is a microtubule-stabilizing protein regulating neuronal polarization and migration
    • Wu Q-F, Yang L, Li S, Wang Q, Yuan X-B, Gao X, Bao L, Zhang X: Fibroblast growth factor 13 is a microtubule-stabilizing protein regulating neuronal polarization and migration. Cell 2012, 149: 1549-1564. doi:10.1016/j.cell.2012.04.046
    • (2012) Cell , vol.149 , pp. 1549-1564
    • Wu, Q.-F.1    Yang, L.2    Li, S.3    Wang, Q.4    Yuan, X.-B.5    Gao, X.6    Bao, L.7    Zhang, X.8
  • 108
    • 34547230356 scopus 로고    scopus 로고
    • Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria
    • Fu NY, Sukumaran SK, Yu VC: Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria. Proc Natl Acad Sci U S A 2007, 104: 10051-10056. doi:10.1073/pnas.0700007104
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 10051-10056
    • Fu, N.Y.1    Sukumaran, S.K.2    Yu, V.C.3
  • 110
    • 84898863790 scopus 로고    scopus 로고
    • Transcriptional co-repressors and memory storage
    • Schoch H, Abel T: Transcriptional co-repressors and memory storage. Neuropharmacology 2014, 80C: 53-60. doi:10.1016/j.neuropharm.2014.01.003
    • (2014) Neuropharmacology , vol.80C , pp. 53-60
    • Schoch, H.1    Abel, T.2
  • 114
    • 84872094223 scopus 로고    scopus 로고
    • Neural development is dependent on the function of specificity protein 2 in cell cycle progression
    • Liang H, Xiao G, Yin H, Hippenmeyer S, Horowitz JM, Ghashghaei HT: Neural development is dependent on the function of specificity protein 2 in cell cycle progression. Development 2013, 140: 552-561. doi:10.1242/dev.085621
    • (2013) Development , vol.140 , pp. 552-561
    • Liang, H.1    Xiao, G.2    Yin, H.3    Hippenmeyer, S.4    Horowitz, J.M.5    Ghashghaei, H.T.6
  • 115
    • 0024151497 scopus 로고
    • Effect of short-term and long-term lithium treatment on uptake and retention of iodine-131 in rat thyroid
    • Dhawan D, Sharma RR, Sharma R, Dash RJ: Effect of short-term and long-term lithium treatment on uptake and retention of iodine-131 in rat thyroid. Aust J Biol Sci 1988, 41: 387-392.
    • (1988) Aust J Biol Sci , vol.41 , pp. 387-392
    • Dhawan, D.1    Sharma, R.R.2    Sharma, R.3    Dash, R.J.4
  • 118
    • 84898606538 scopus 로고    scopus 로고
    • Analysis of novel NEFL mRNA targeting microRNAs in amyotrophic lateral sclerosis
    • Ishtiaq M, Campos-Melo D, Volkening K, Strong MJ: Analysis of novel NEFL mRNA targeting microRNAs in amyotrophic lateral sclerosis. PLoS One 2014, 9: e85653. doi:10.1371/journal.pone.0085653
    • (2014) PLoS One , vol.9
    • Ishtiaq, M.1    Campos-Melo, D.2    Volkening, K.3    Strong, M.J.4
  • 119
    • 76049093950 scopus 로고    scopus 로고
    • Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression
    • Chung CY, Koprich JB, Hallett PJ, Isacson O: Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression. Proc Natl Acad Sci U S A 2009, 106: 22474-22479. doi:10.1073/pnas.0912193106
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 22474-22479
    • Chung, C.Y.1    Koprich, J.B.2    Hallett, P.J.3    Isacson, O.4
  • 120
    • 57449100832 scopus 로고    scopus 로고
    • Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: a potential mechanism leading to chronic inflammation
    • Walker DG, Dalsing-Hernandez JE, Campbell NA, Lue L-F: Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: a potential mechanism leading to chronic inflammation. Exp Neurol 2009, 215: 5-19. doi:10.1016/j.expneurol.2008.09.003
    • (2009) Exp Neurol , vol.215 , pp. 5-19
    • Walker, D.G.1    Dalsing-Hernandez, J.E.2    Campbell, N.A.3    Lue, L.-F.4
  • 121
    • 34547681540 scopus 로고    scopus 로고
    • CD200-CD200R regulation of microglia activation in the pathogenesis of Parkinson's disease
    • Wang X-J, Ye M, Zhang Y-H, Chen S-D: CD200-CD200R regulation of microglia activation in the pathogenesis of Parkinson's disease. J Neuroimmune Pharmacol 2007, 2: 259-264. doi:10.1007/s11481-007-9075-1
    • (2007) J Neuroimmune Pharmacol , vol.2 , pp. 259-264
    • Wang, X.-J.1    Ye, M.2    Zhang, Y.-H.3    Chen, S.-D.4
  • 122
    • 84902282100 scopus 로고    scopus 로고
    • Metallothioneins and the Central Nervous System: From a Deregulation in Neurodegenerative Diseases to the Development of New Therapeutic Approaches
    • Bolognin S, Cozzi B, Zambenedetti P, Zatta P: Metallothioneins and the Central Nervous System: From a Deregulation in Neurodegenerative Diseases to the Development of New Therapeutic Approaches. J Alzheimers Dis 2014, doi:10.3233/JAD-130290.
    • (2014) J Alzheimers Dis
    • Bolognin, S.1    Cozzi, B.2    Zambenedetti, P.3    Zatta, P.4
  • 124
    • 84898018919 scopus 로고    scopus 로고
    • Computational deconvolution: extracting cell type-specific information from heterogeneous samples
    • Shen-Orr SS, Gaujoux R: Computational deconvolution: extracting cell type-specific information from heterogeneous samples. Curr Opin Immunol 2013, 25: 571-578. doi:10.1016/j.coi.2013.09.015
    • (2013) Curr Opin Immunol , vol.25 , pp. 571-578
    • Shen-Orr, S.S.1    Gaujoux, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.