Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation

PLoS Genetics

Volumn 8, Issue 6, 2012, Pages

  Dumitriu, Alexandra ^a,b   Latourelle, Jeanne C ^a   Hadzi, Tiffany C ^a   Pankratz, Nathan ^c   Garza, Dan ^d   Miller, John P ^d   Vance, Jeffery M ^e   Foroud, Tatiana ^f   Beach, Thomas G ^g   Myers, Richard H ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Boston University   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d Proteostasis Therapeutics   (United States)

^e UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^f INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g SUN HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR FKHR; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; GAK PROTEIN, HUMAN; OXIDOREDUCTASE; POLYAMINE OXIDASE; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE;

ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; CYCLIN G ASSOCIATED KINASE GENE; FORKHEAD BOX O1 GENE; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE PROBE; GENETIC ASSOCIATION; GENOTYPING TECHNIQUE; HUMAN; HUMAN TISSUE; MALE; MICROARRAY ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; PARKINSON DISEASE; PREFRONTAL CORTEX; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; SPERMINE OXIDASE GENE; SUBSTANTIA NIGRA; TRANSCRIPTION REGULATION; AGED; DNA MICROARRAY; GENE REGULATORY NETWORK; GENETICS; LEWY BODY; META ANALYSIS; METABOLISM; ONSET AGE;

AGE OF ONSET; AGED, 80 AND OVER; BINDING SITES; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEWY BODIES; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PARKINSON DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREFRONTAL CORTEX; PROTEIN-SERINE-THREONINE KINASES;

EID: 84864026404     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002794     Document Type: Article

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