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Volumn 111, Issue 12, 2004, Pages 1543-1573

Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes

Author keywords

Affymetrix; Cerebellum; Gene expression; HSC70; Iron; Parkinson's disease; Quantitative real time PCR; SKP1A; Substantia nigra pars compacta; Ubiquitin proteasome system

Indexed keywords

HEAT SHOCK PROTEIN; IRON; PROTEASOME; PROTEIN; SKP1A PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 19944428747     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00702-004-0212-1     Document Type: Article
Times cited : (315)

References (89)
  • 1
    • 0015619876 scopus 로고
    • Monoamine oxidase and aldehyde dehydrogenase activity in the striatum of rats after 6-hydroxydopamine lesion of the nigrostriatal pathway
    • Agid Y, Javoy F, Youdim MBH (1973) Monoamine oxidase and aldehyde dehydrogenase activity in the striatum of rats after 6-hydroxydopamine lesion of the nigrostriatal pathway. Br J Pharmacol 48(1): 175-178
    • (1973) Br J Pharmacol , vol.48 , Issue.1 , pp. 175-178
    • Agid, Y.1    Javoy, F.2    Youdim, M.B.H.3
  • 2
    • 0036468432 scopus 로고    scopus 로고
    • Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
    • Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM (2002) Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295(5556): 865-868
    • (2002) Science , vol.295 , Issue.5556 , pp. 865-868
    • Auluck, P.K.1    Chan, H.Y.2    Trojanowski, J.Q.3    Lee, V.M.4    Bonini, N.M.5
  • 6
    • 0037059040 scopus 로고    scopus 로고
    • Chaperoning brain degeneration
    • 90004
    • Bonini NM (2002) Chaperoning brain degeneration. PNAS 99(90004): 16407-16411
    • (2002) PNAS , vol.99 , pp. 16407-16411
    • Bonini, N.M.1
  • 7
    • 0030668423 scopus 로고    scopus 로고
    • Diagnostic criteria for neuropathologic assessment of Alzheimer's disease
    • Braak H, Braak E (1997) Diagnostic criteria for neuropathologic assessment of Alzheimer's disease. Neurobiol Aging 18 [Suppl 4]: S85-S88
    • (1997) Neurobiol Aging , vol.18 , Issue.4 SUPPL.
    • Braak, H.1    Braak, E.2
  • 8
    • 0037378772 scopus 로고    scopus 로고
    • Imaging end points for monitoring neuroprotection in Parkinson's disease
    • discussion S118-S119
    • Brooks DJ (2003) Imaging end points for monitoring neuroprotection in Parkinson's disease. Ann Neurol 53 [Suppl 3]: S110-S118; discussion S118-S119
    • (2003) Ann Neurol , vol.53 , Issue.3 SUPPL.
    • Brooks, D.J.1
  • 9
    • 0141987860 scopus 로고    scopus 로고
    • The ubiquitin proteasome system in neurodegenerative diseases: Sometimes the chicken, sometimes the egg
    • Ciechanover A, Brundin P (2003) The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg. Neuron 40(2): 427-446
    • (2003) Neuron , vol.40 , Issue.2 , pp. 427-446
    • Ciechanover, A.1    Brundin, P.2
  • 10
    • 0037022186 scopus 로고    scopus 로고
    • Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro
    • Cohlberg JA, Li J, Uversky VN, Fink AL (2002) Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro. Biochemistry 41(5): 1502-1511
    • (2002) Biochemistry , vol.41 , Issue.5 , pp. 1502-1511
    • Cohlberg, J.A.1    Li, J.2    Uversky, V.N.3    Fink, A.L.4
  • 11
    • 0035058466 scopus 로고    scopus 로고
    • Activation of cell-cycle-associated proteins in neuronal death: A mandatory or dispensable path?
    • Copani A, Uberti D, Sortino MA, Bruno V, Nicoletti F, Memo M (2001) Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path? Trends Neurosci 24(1): 25-31
    • (2001) Trends Neurosci , vol.24 , Issue.1 , pp. 25-31
    • Uberti D, C.A.1    Sortino, M.A.2    Bruno, V.3    Nicoletti, F.4    Memo, M.5
  • 12
    • 0030016595 scopus 로고    scopus 로고
    • Structure and functions of the 26S and 26S proteasomes
    • Coux O, Tanaka K, Goldberg AL (1996) Structure and functions of the 26S and 26S proteasomes. Annu Rev Biochem 65: 801-847
    • (1996) Annu Rev Biochem , vol.65 , pp. 801-847
    • Coux, O.1    Tanaka, K.2    Goldberg, A.L.3
  • 13
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. Neuron 39(6): 889-909
    • (2003) Neuron , vol.39 , Issue.6 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 14
    • 0242363670 scopus 로고    scopus 로고
    • Molecular pathways of neurodegeneration in Parkinson's disease
    • Dawson TM, Dawson VL (2003) Molecular pathways of neurodegeneration in Parkinson's disease. Science 302(5646): 819-822
    • (2003) Science , vol.302 , Issue.5646 , pp. 819-822
    • Dawson, T.M.1    Dawson, V.L.2
  • 15
    • 0033850796 scopus 로고    scopus 로고
    • Wnt signaling function in Alzheimer's disease
    • De Ferrari GV, Inestrosa NC (2000) Wnt signaling function in Alzheimer's disease. Brain Res Rev 33(1): 1-12
    • (2000) Brain Res Rev , vol.33 , Issue.1 , pp. 1-12
    • De Ferrari, G.V.1    Inestrosa, N.C.2
  • 18
    • 0015381043 scopus 로고
    • Aldehyde dehydrogenase and monoamine oxidase in the striatum of cats with nigrostriatal lesions
    • Duncan RJ, Sourkes TL, Boucher R, Poirier LJ, Roberge A (1972) Aldehyde dehydrogenase and monoamine oxidase in the striatum of cats with nigrostriatal lesions. J Neurochem 19(8): 2007-2010
    • (1972) J Neurochem , vol.19 , Issue.8 , pp. 2007-2010
    • Duncan, R.J.1    Sourkes, T.L.2    Boucher, R.3    Poirier, L.J.4    Roberge, A.5
  • 22
    • 0033671869 scopus 로고    scopus 로고
    • Identification and characterization of novel isoforms of COP I subunits
    • Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (2000) Identification and characterization of novel isoforms of COP I subunits. J Biochem 128(5): 793-801
    • (2000) J Biochem , vol.128 , Issue.5 , pp. 793-801
    • Futatsumori, M.1    Kasai, K.2    Takatsu, H.3    Shin, H.W.4    Nakayama, K.5
  • 23
    • 0348109455 scopus 로고    scopus 로고
    • ALDH1 mRNA: Presence in human dopamine neurons and decreases in substantia nigra in Parkinson's disease and in the ventral tegmental area in schizophrenia
    • Galter D, Buervenich S, Carmine A, Anvret M, Olson L (2003) ALDH1 mRNA: presence in human dopamine neurons and decreases in substantia nigra in Parkinson's disease and in the ventral tegmental area in schizophrenia. Neurobiol Dis 14(3): 637-647
    • (2003) Neurobiol Dis , vol.14 , Issue.3 , pp. 637-647
    • Galter, D.1    Buervenich, S.2    Carmine, A.3    Anvret, M.4    Olson, L.5
  • 24
    • 0033788434 scopus 로고    scopus 로고
    • Rat alpha-synuclein interacts with Tat binding protein 1, a component of the 26S proteasomal complex
    • Ghee M, Fournier A, Mallet J (2000) Rat alpha-synuclein interacts with Tat binding protein 1, a component of the 26S proteasomal complex. J Neurochem 75(5): 2221-2224
    • (2000) J Neurochem , vol.75 , Issue.5 , pp. 2221-2224
    • Ghee, M.1    Fournier, A.2    Mallet, J.3
  • 25
    • 0027444947 scopus 로고
    • S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase
    • Ghislain M, Udvardy A, Mann C (1993) S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase. Nature 366(6453): 358-362
    • (1993) Nature , vol.366 , Issue.6453 , pp. 358-362
    • Ghislain, M.1    Udvardy, A.2    Mann, C.3
  • 26
    • 0036083396 scopus 로고    scopus 로고
    • The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
    • Glickman MH, Ciechanover A (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82(2): 373-428
    • (2002) Physiol Rev , vol.82 , Issue.2 , pp. 373-428
    • Glickman, M.H.1    Ciechanover, A.2
  • 27
    • 0032483546 scopus 로고    scopus 로고
    • A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3
    • Glickman MH, Rubin DM, Coux O, Wefes I, Pfeifer G, Cjeka Z, Baumeister W, Fried VA, Finley D (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94(5): 615-623
    • (1998) Cell , vol.94 , Issue.5 , pp. 615-623
    • Glickman, M.H.1    Rubin, D.M.2    Coux, O.3    Wefes, I.4    Pfeifer, G.5    Cjeka, Z.6    Baumeister, W.7    Fried, V.A.8    Finley, D.9
  • 28
    • 0033582905 scopus 로고    scopus 로고
    • Regulation of membrane trafficking: Structural insights from a Rab/effector complex
    • Gonzalez L Jr, Scheller RH (1999) Regulation of membrane trafficking: structural insights from a Rab/effector complex. Cell 96(6): 755-758
    • (1999) Cell , vol.96 , Issue.6 , pp. 755-758
    • Gonzalez Jr., L.1    Scheller, R.H.2
  • 29
    • 0027379925 scopus 로고
    • Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit
    • Gordon C, McGurk G, Dillon P, Rosen C, Hastie ND (1993) Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit. Nature 366(6453): 355-357
    • (1993) Nature , vol.366 , Issue.6453 , pp. 355-357
    • Gordon, C.1    McGurk, G.2    Dillon, P.3    Rosen, C.4    Hastie, N.D.5
  • 30
    • 0027937548 scopus 로고
    • Oxidative stress: Free radical production in neural degeneration
    • Götz ME, Kunig G, Riederer P, Youdim MB (1994) Oxidative stress: free radical production in neural degeneration. Pharmacol Ther 63(1): 37-122
    • (1994) Pharmacol Ther , vol.63 , Issue.1 , pp. 37-122
    • Götz, M.E.1    Kunig, G.2    Riederer, P.3    Youdim, M.B.4
  • 31
    • 0034941949 scopus 로고    scopus 로고
    • Gene expression analysis in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: Effect of R-apomorphine
    • Grünblatt E, Mandel S, Maor G, Youdim MBH (2001) Gene expression analysis in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of R-apomorphine. J Neurochem 78(1): 1-12
    • (2001) J Neurochem , vol.78 , Issue.1 , pp. 1-12
    • Grünblatt, E.1    Mandel, S.2    Maor, G.3    Youdim, M.B.H.4
  • 32
    • 0141890273 scopus 로고    scopus 로고
    • Oxygen and iron regulation of iron regulatory protein 2
    • Hanson ES, Rawlins ML, Leibold EA (2003) Oxygen and iron regulation of iron regulatory protein 2. J Biol Chem 278(41): 40337-40342
    • (2003) J Biol Chem , vol.278 , Issue.41 , pp. 40337-40342
    • Hanson, E.S.1    Rawlins, M.L.2    Leibold, E.A.3
  • 33
    • 0030026109 scopus 로고    scopus 로고
    • Dopamine transporter (Dat) and synaptic vesicle amine transporter (VMAT2) gene expression in the substantia nigra of control and Parkinson's disease
    • Harrington KA, Augood SJ, Kingsbury AE, Foster OJ, Emson PC (1996) Dopamine transporter (Dat) and synaptic vesicle amine transporter (VMAT2) gene expression in the substantia nigra of control and Parkinson's disease. Brain Res Mol Brain Res 36(1): 157-162
    • (1996) Brain Res Mol Brain Res , vol.36 , Issue.1 , pp. 157-162
    • Harrington, K.A.1    Augood, S.J.2    Kingsbury, A.E.3    Foster, O.J.4    Emson, P.C.5
  • 34
    • 2542499831 scopus 로고    scopus 로고
    • Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease
    • Hashimoto M, Bar-On P, Ho G, Takenouchi T, Rockenstein E, Crews L, Masliah E (2004) Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease. J Biol Chem 279(22): 23622-23629
    • (2004) J Biol Chem , vol.279 , Issue.22 , pp. 23622-23629
    • Hashimoto, M.1    Bar-On, P.2    Ho, G.3    Takenouchi, T.4    Rockenstein, E.5    Crews, L.6    Masliah, E.7
  • 35
    • 0029864178 scopus 로고    scopus 로고
    • Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus
    • Hay JC, Hirling H, Scheller RH (1996) Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus. J Biol Chem 271(10): 5671-5679
    • (1996) J Biol Chem , vol.271 , Issue.10 , pp. 5671-5679
    • Hay, J.C.1    Hirling, H.2    Scheller, R.H.3
  • 36
    • 0021166316 scopus 로고
    • Hepatic aldehyde dehydrogenases and lipid peroxidation
    • Hjelle JJ, Petersen DR (1983) Hepatic aldehyde dehydrogenases and lipid peroxidation. Pharmacol Biochem Behav 18 [Suppl 1]: 155-160
    • (1983) Pharmacol Biochem Behav , vol.18 , Issue.1 SUPPL. , pp. 155-160
    • Hjelle, J.J.1    Petersen, D.R.2
  • 37
    • 0014082977 scopus 로고
    • Parkinsonism: Onset, progression and mortality
    • Hoehn MM, Yahr MD (1967) Parkinsonism: onset, progression and mortality. Neurology 17(5): 427-442
    • (1967) Neurology , vol.17 , Issue.5 , pp. 427-442
    • Hoehn, M.M.1    Yahr, M.D.2
  • 38
  • 39
    • 0036345454 scopus 로고    scopus 로고
    • CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity
    • Imai Y, Soda M, Hatakeyama S, Akagi T, Hashikawa T, Nakayama KI, Takahashi R (2002) CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol Cell 10(1): 55-67
    • (2002) Mol Cell , vol.10 , Issue.1 , pp. 55-67
    • Imai, Y.1    Soda, M.2    Hatakeyama, S.3    Akagi, T.4    Hashikawa, T.5    Nakayama, K.I.6    Takahashi, R.7
  • 40
    • 0141725659 scopus 로고    scopus 로고
    • Neuropathological spectrum of synucleinopathies
    • Jellinger KA (2003) Neuropathological spectrum of synucleinopathies. Mov Disord 18 [Suppl 6]: S2-S12
    • (2003) Mov Disord , vol.18 , Issue.6 SUPPL.
    • Jellinger, K.A.1
  • 41
    • 0031899172 scopus 로고    scopus 로고
    • Oxidative mechanisms in nigral cell death in Parkinson's disease
    • Jenner P (1998) Oxidative mechanisms in nigral cell death in Parkinson's disease. Mov Disord [Suppl 13]: 24-34
    • (1998) Mov Disord , Issue.13 SUPPL. , pp. 24-34
    • Jenner, P.1
  • 42
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • Jenner P, Olanow CW (1996) Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 47[6 Suppl 3]: S161-S170
    • (1996) Neurology , vol.47 , Issue.6 SUPPL. 3
    • Jenner, P.1    Olanow, C.W.2
  • 44
    • 2942620074 scopus 로고    scopus 로고
    • Hsp70 reduces alpha-synuclein aggregation and toxicity
    • Klucken J, Shin Y, Masliah E, Hyman BT, McLean PJ (2004) Hsp70 reduces alpha-synuclein aggregation and toxicity. J Biol Chem 279(24): 25497-25502
    • (2004) J Biol Chem , vol.279 , Issue.24 , pp. 25497-25502
    • Klucken, J.1    Shin, Y.2    Masliah, E.3    Hyman, B.T.4    McLean, P.J.5
  • 46
    • 1642387020 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF-1)alpha: Its protein stability and biological functions
    • Lee JW, Bae SH, Jeong J, Kim SH, Kim KW (2004) Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions. Exp Mol Med 29;36(1):1-12
    • (2004) Exp Mol Med , vol.36 , Issue.1 , pp. 1-12
    • Lee, J.W.1    Bae, S.H.2    Jeong, J.3    Kim, S.H.4    Kim, K.W.5
  • 48
    • 0031453714 scopus 로고    scopus 로고
    • Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex
    • Lukiw WJ, Bazan NG (1997) Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex. J Neurosci Res 50(6): 937-945
    • (1997) J Neurosci Res , vol.50 , Issue.6 , pp. 937-945
    • Lukiw, W.J.1    Bazan, N.G.2
  • 49
    • 0022844901 scopus 로고
    • Human class I alcohol dehydrogenases catalyze the interconversion of alcohols and aldehydes in the metabolism of dopamine
    • Mardh G, Vallee BL (1986) Human class I alcohol dehydrogenases catalyze the interconversion of alcohols and aldehydes in the metabolism of dopamine. Biochemistry 25(23): 7279-7282
    • (1986) Biochemistry , vol.25 , Issue.23 , pp. 7279-7282
    • Mardh, G.1    Vallee, B.L.2
  • 50
    • 11244275423 scopus 로고    scopus 로고
    • Parkinson's disease-associated mutant synphilin-1 mediates proteasomal inhibition and interacts with regulatory proteasomal protein S6
    • Marx FP, Berg D, Dawson S, Riess O, Schultz JB, Krueger R (2004) Parkinson's disease-associated mutant synphilin-1 mediates proteasomal inhibition and interacts with regulatory proteasomal protein S6. Mov Disord 19 [Suppl 9]: S83
    • (2004) Mov Disord , vol.19 , Issue.9 SUPPL.
    • Marx, F.P.1    Berg, D.2    Dawson, S.3    Riess, O.4    Schultz, J.B.5    Krueger, R.6
  • 51
    • 0037025111 scopus 로고    scopus 로고
    • Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease
    • McNaught KS, Belizaire R, Jenner P, Olanow CW, Isacson O (2002) Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease. Neurosci Lett 326(3): 155-158
    • (2002) Neurosci Lett , vol.326 , Issue.3 , pp. 155-158
    • McNaught, K.S.1    Belizaire, R.2    Jenner, P.3    Olanow, C.W.4    Isacson, O.5
  • 53
    • 2042476718 scopus 로고    scopus 로고
    • A critical review of the development and importance of proteinaceous aggregates in animal models of Parkinson's disease: New insights into Lewy body formation
    • Meredith GE, Halliday GM, Totterdell S (2004) A critical review of the development and importance of proteinaceous aggregates in animal models of Parkinson's disease: new insights into Lewy body formation. Parkinsonism Relat Disord 10(4): 191-202
    • (2004) Parkinsonism Relat Disord , vol.10 , Issue.4 , pp. 191-202
    • Meredith, G.E.1    Halliday, G.M.2    Totterdell, S.3
  • 55
    • 0242710750 scopus 로고    scopus 로고
    • Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase gene family (PFKFB-1-4) expression in vivo
    • Minchenko O, Opentanova I, Caro J (2003) Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo. FEBS Lett 554(3): 264-270
    • (2003) FEBS Lett , vol.554 , Issue.3 , pp. 264-270
    • Minchenko, O.1    Opentanova, I.2    Caro, J.3
  • 56
    • 0037401714 scopus 로고    scopus 로고
    • CHIP: A quality-control E3 ligase collaborating with molecular chaperones
    • Murata S, Chiba T, Tanaka K (2003) CHIP: a quality-control E3 ligase collaborating with molecular chaperones. Int J Biochem Cell Biol 35(5): 572-578
    • (2003) Int J Biochem Cell Biol , vol.35 , Issue.5 , pp. 572-578
    • Murata, S.1    Chiba, T.2    Tanaka, K.3
  • 57
    • 0002563935 scopus 로고    scopus 로고
    • Iron and neurodegeneration: Prospects for neuroprotection
    • Olanow CW, Jenner P, Youdim MB (eds) Academic Press, London
    • Olanow CW, Youdim MB (1996) Iron and neurodegeneration: prospects for neuroprotection. In: Olanow CW, Jenner P, Youdim MB (eds) Neurodegeneration and neuroprotection in Parkinson's disease. Academic Press, London, pp 55-69
    • (1996) Neurodegeneration and Neuroprotection in Parkinson's Disease , pp. 55-69
    • Olanow, C.W.1    Youdim, M.B.2
  • 58
    • 0034663039 scopus 로고    scopus 로고
    • The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity
    • Ostrerova-Golts N, Petrucelli L, Hardy J, Lee JM, Farer M, Wolozin B (2000) The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity. J Neurosci 20(16): 6048-6054
    • (2000) J Neurosci , vol.20 , Issue.16 , pp. 6048-6054
    • Ostrerova-Golts, N.1    Petrucelli, L.2    Hardy, J.3    Lee, J.M.4    Farer, M.5    Wolozin, B.6
  • 59
    • 0024478385 scopus 로고
    • ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain
    • Ouimet CC, Hemmings HC Jr, Greengard P (1989) ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain. J Neurosci 9(3): 865-875
    • (1989) J Neurosci , vol.9 , Issue.3 , pp. 865-875
    • Ouimet, C.C.1    Hemmings Jr., H.C.2    Greengard, P.3
  • 60
    • 0033570320 scopus 로고    scopus 로고
    • Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis
    • Padmanabhan J, Park DS, Greene LA, Shelanski ML (1999) Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. J Neurosci 19(20): 8747-8756
    • (1999) J Neurosci , vol.19 , Issue.20 , pp. 8747-8756
    • Padmanabhan, J.1    Park, D.S.2    Greene, L.A.3    Shelanski, M.L.4
  • 61
    • 1842608738 scopus 로고    scopus 로고
    • Hereditary causes of disturbed iron homeostasis in the central nervous system
    • Ponka P (2004) Hereditary causes of disturbed iron homeostasis in the central nervous system. Ann NY Acad Sci 1012: 267-281
    • (2004) Ann NY Acad Sci , vol.1012 , pp. 267-281
    • Ponka, P.1
  • 62
    • 0037189591 scopus 로고    scopus 로고
    • Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein
    • Ribeiro CS, Carneiro K, Ross CA, Menezes JR, Engelender S (2002) Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein. J Biol Chem 277(26): 23927-23933
    • (2002) J Biol Chem , vol.277 , Issue.26 , pp. 23927-23933
    • Ribeiro, C.S.1    Carneiro, K.2    Ross, C.A.3    Menezes, J.R.4    Engelender, S.5
  • 64
    • 4143052254 scopus 로고    scopus 로고
    • Quantitative real-time PCR - Eine Frage der Normalisierung
    • Schulz H, Weber B, Wiedmann C (2004) Quantitative real-time PCR - eine Frage der Normalisierung. BIO Spektrum 1: 99-101
    • (2004) BIO Spektrum , vol.1 , pp. 99-101
    • Schulz, H.1    Weber, B.2    Wiedmann, C.3
  • 65
    • 0037673562 scopus 로고    scopus 로고
    • The comparative proteomics of ubiquitination in mouse
    • Semple CA (2003) The comparative proteomics of ubiquitination in mouse. Genome Res 13(6B): 1389-1394
    • (2003) Genome Res , vol.13 , Issue.6 B , pp. 1389-1394
    • Semple, C.A.1
  • 66
    • 0035139109 scopus 로고    scopus 로고
    • Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases
    • Sherman MY, Goldberg AL (2001) Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases. Neuron 29(1): 15-32
    • (2001) Neuron , vol.29 , Issue.1 , pp. 15-32
    • Sherman, M.Y.1    Goldberg, A.L.2
  • 67
    • 0038413759 scopus 로고    scopus 로고
    • Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function
    • Snyder H, Mensah K, Theisler C, Lee J, Matouschek A, Wolozin B (2003) Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function. J Biol Chem 278(14): 11753-11759
    • (2003) J Biol Chem , vol.278 , Issue.14 , pp. 11753-11759
    • Snyder, H.1    Mensah, K.2    Theisler, C.3    Lee, J.4    Matouschek, A.5    Wolozin, B.6
  • 68
    • 0037422010 scopus 로고    scopus 로고
    • Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
    • Staropoli JF, McDermott C, Martinat C, Schulman B, Demireva E, Abeliovich A (2003) Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Neuron 37(5): 735-749
    • (2003) Neuron , vol.37 , Issue.5 , pp. 735-749
    • Staropoli, J.F.1    McDermott, C.2    Martinat, C.3    Schulman, B.4    Demireva, E.5    Abeliovich, A.6
  • 69
    • 0032945938 scopus 로고    scopus 로고
    • Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone
    • Stenoien DL, Cummings CJ, Adams HP, Mancini MG, Patel K, DeMartino GN, Marcelli M, Weigel NL, Mancini MA (1999) Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone. Hum Mol Genet 8(5): 731-741
    • (1999) Hum Mol Genet , vol.8 , Issue.5 , pp. 731-741
    • Stenoien, D.L.1    Cummings, C.J.2    Adams, H.P.3    Mancini, M.G.4    Patel, K.5    Demartino, G.N.6    Marcelli, M.7    Weigel, N.L.8    Mancini, M.A.9
  • 70
    • 0034090632 scopus 로고    scopus 로고
    • Recognition of misfolding proteins by PA700, the regulatory subcomplex of the 26S proteasome
    • Strickland E, Hakala K, Thomas PJ, DeMartino GN (2000) Recognition of misfolding proteins by PA700, the regulatory subcomplex of the 26S proteasome. J Biol Chem 275(8): 5565-5572
    • (2000) J Biol Chem , vol.275 , Issue.8 , pp. 5565-5572
    • Strickland, E.1    Hakala, K.2    Thomas, P.J.3    DeMartino, G.N.4
  • 72
    • 1042266326 scopus 로고    scopus 로고
    • Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective
    • Tanaka M, Kim YM, Lee G, Junn E, Iwatsubo T, Mouradian MM (2004) Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective. J Biol Chem 279(6): 4625-4631
    • (2004) J Biol Chem , vol.279 , Issue.6 , pp. 4625-4631
    • Tanaka, M.1    Kim, Y.M.2    Lee, G.3    Junn, E.4    Iwatsubo, T.5    Mouradian, M.M.6
  • 73
    • 0027339850 scopus 로고
    • Dopamine Dl agonist SKF 38393 increases the state of phosphorylation of ARPP-21 in substantia nigra
    • Tsou K, Girault JA, Greengard P (1993) Dopamine Dl agonist SKF 38393 increases the state of phosphorylation of ARPP-21 in substantia nigra. J Neurochem 60(3): 1043-1046
    • (1993) J Neurochem , vol.60 , Issue.3 , pp. 1043-1046
    • Tsou, K.1    Girault, J.A.2    Greengard, P.3
  • 74
    • 0033664434 scopus 로고    scopus 로고
    • Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70
    • Tsukahara F, Yoshioka T, Muraki T (2000) Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70. Mol Pharmacol 58(6): 1257-1263
    • (2000) Mol Pharmacol , vol.58 , Issue.6 , pp. 1257-1263
    • Tsukahara, F.1    Yoshioka, T.2    Muraki, T.3
  • 75
    • 0035873812 scopus 로고    scopus 로고
    • Alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro
    • Turnbull S, Tabner BJ, El-Agnaf OM, Moore S, Davies Y, Allsop D (2001) alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro. Free Radie Biol Med 30(10): 1163-1170
    • (2001) Free Radie Biol Med , vol.30 , Issue.10 , pp. 1163-1170
    • Turnbull, S.1    Tabner, B.J.2    El-Agnaf, O.M.3    Moore, S.4    Davies, Y.5    Allsop, D.6
  • 76
    • 0036667913 scopus 로고    scopus 로고
    • Fluorescent multicolor multiplex homogeneous assay for the simultaneous analysis of the two most common hemochromatosis mutations
    • Ugozzoli LA, Chinn D, Hamby K (2002) Fluorescent multicolor multiplex homogeneous assay for the simultaneous analysis of the two most common hemochromatosis mutations. Anal Biochem 307(1): 47-53
    • (2002) Anal Biochem , vol.307 , Issue.1 , pp. 47-53
    • Ugozzoli, L.A.1    Chinn, D.2    Hamby, K.3
  • 77
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3(7): RESEARCH0034
    • (2002) Genome Biol , vol.3 , Issue.7
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 79
    • 0032867676 scopus 로고    scopus 로고
    • The 26S proteasome: A molecular machine designed for controlled proteolysis
    • Voges D, Zwickl P, Baumeister W (1999) The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 68: 1015-1068
    • (1999) Annu Rev Biochem , vol.68 , pp. 1015-1068
    • Voges, D.1    Zwickl, P.2    Baumeister, W.3
  • 81
    • 0032559642 scopus 로고    scopus 로고
    • SRPK2: A differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells
    • Wang HY, Lin W, Dyck JA, Yeakley JM, Songyang Z, Cantley LC, Fu XD (1998) SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. J Cell Biol 140(4): 737-750
    • (1998) J Cell Biol , vol.140 , Issue.4 , pp. 737-750
    • Wang, H.Y.1    Lin, W.2    Dyck, J.A.3    Yeakley, J.M.4    Songyang, Z.5    Cantley, L.C.6    Fu, X.D.7
  • 82
    • 1642458415 scopus 로고    scopus 로고
    • Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity
    • Wang J, Chen G, Muckenthaler M, Galy B, Hentze MW, Pantopoulos K (2004) Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity. Mol Cell Biol 24(3): 954-965
    • (2004) Mol Cell Biol , vol.24 , Issue.3 , pp. 954-965
    • Wang, J.1    Chen, G.2    Muckenthaler, M.3    Galy, B.4    Hentze, M.W.5    Pantopoulos, K.6
  • 83
    • 0034839484 scopus 로고    scopus 로고
    • Syntaxin 6: The promiscuous behaviour of a SNARE protein
    • Wendler F, Tooze S (2001) Syntaxin 6: the promiscuous behaviour of a SNARE protein. Traffic 2(9): 606-611
    • (2001) Traffic , vol.2 , Issue.9 , pp. 606-611
    • Wendler, F.1    Tooze, S.2
  • 85
    • 0027497409 scopus 로고
    • The possible role of iron in the etiopathology of Parkinson's disease
    • Youdim MB, Ben-Shachar D, Riederer P (1993) The possible role of iron in the etiopathology of Parkinson's disease. Mov Disord 8(1): 1-12
    • (1993) Mov Disord , vol.8 , Issue.1 , pp. 1-12
    • Youdim, M.B.1    Ben-Shachar, D.2    Riederer, P.3
  • 86
    • 0030641754 scopus 로고    scopus 로고
    • Understanding Parkinson's disease
    • Youdim MBH, Riederer P (1997) Understanding Parkinson's disease. Sci Am 276(1): 52-59
    • (1997) Sci Am , vol.276 , Issue.1 , pp. 52-59
    • Youdim, M.B.H.1    Riederer, P.2
  • 87
    • 3042530369 scopus 로고    scopus 로고
    • Iron in the brain, normal and pathological
    • Adelman G, Smith B (eds) Elsevier, Amsterdam
    • Youdim MBH, Riederer P (2004) Iron in the brain, normal and pathological. In: Adelman G, Smith B (eds) Encyclopedia of neuroscience, 3rd edn. Elsevier, Amsterdam
    • (2004) Encyclopedia of Neuroscience, 3rd Edn.
    • Youdim, M.B.H.1    Riederer, P.2
  • 88
    • 4444239787 scopus 로고    scopus 로고
    • Proteomic approach to studying Parkinson's disease
    • Zhang J, Goodlett DR (2004) Proteomic approach to studying Parkinson's disease. Mol Neurobiol 29(3): 271-288
    • (2004) Mol Neurobiol , vol.29 , Issue.3 , pp. 271-288
    • Zhang, J.1    Goodlett, D.R.2
  • 89
    • 0035400710 scopus 로고    scopus 로고
    • Molecular chaperones and the regulation of neurotransmitter exocytosis
    • Zinsmaier KE, Bronk P (2001) Molecular chaperones and the regulation of neurotransmitter exocytosis. Biochem Pharmacol 62(1): 1-11
    • (2001) Biochem Pharmacol , vol.62 , Issue.1 , pp. 1-11
    • Zinsmaier, K.E.1    Bronk, P.2


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