Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C

Pain

Volumn 105, Issue 1-2, 2003, Pages 133-141

  Fehrenbacher, Jill C ^a   Taylor, Charles P ^b   Vasko, Michael R ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PFIZER INC   (United States)

Author keywords

Gabapentin; Inflammation; Neuropeptide release; Protein kinase C

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; FREUND ADJUVANT; GABAPENTIN; NEUROPEPTIDE; PHORBOL DIBUTYRATE; PREGABALIN; PROTEIN KINASE C; PROTEIN KINASE C ACTIVATOR; SUBSTANCE P;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; INJECTION; MALE; MYELITIS; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; SENSORY NERVE CELL; SIGNAL TRANSDUCTION;

EID: 0141738762     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(03)00173-8     Document Type: Article

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