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Volumn 7, Issue 5, 2016, Pages 319-334

mRNA vaccine delivery using lipid nanoparticles

Author keywords

adjuvant; cancer immunotherapy; cationic lipid; drug delivery; lipid nanoparticle; mRNA; oligonucleotide; therapeutic vaccine; vaccine

Indexed keywords

DNA VACCINE; MRNA VACCINE; RNA VACCINE; SOLID LIPID NANOPARTICLE; SUBUNIT VACCINE; UNCLASSIFIED DRUG; LIPID; MESSENGER RNA; NANOPARTICLE; VACCINE;

EID: 84964930086     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde-2016-0006     Document Type: Article
Times cited : (454)

References (145)
  • 2
    • 77958469466 scopus 로고    scopus 로고
    • Immunologic basis of vaccine vectors
    • Liu MA. Immunologic basis of vaccine vectors. Immunity 33(4), 504-515 (2010).
    • (2010) Immunity , vol.33 , Issue.4 , pp. 504-515
    • Liu, M.A.1
  • 3
    • 0028312255 scopus 로고
    • Recombinant vector vaccines in vaccinology
    • Hilleman MR. Recombinant vector vaccines in vaccinology. Dev. Biol. Stand. 82, 3-20 (1994).
    • (1994) Dev. Biol. Stand. , vol.82 , pp. 3-20
    • Hilleman, M.R.1
  • 5
    • 39349103969 scopus 로고    scopus 로고
    • Vaccination with messenger RNA (mRNA)
    • Bauer PDS, Hartmann PDG (Eds). Springer Berlin Heidelberg, Germany
    • Pascolo S. Vaccination with messenger RNA (mRNA). In: Toll-Like Receptors (TLRs) and Innate Immunity. Bauer PDS, Hartmann PDG (Eds). Springer Berlin Heidelberg, Germany 221-235 (2008).
    • (2008) Toll-Like Receptors (TLRs) and Innate Immunity , pp. 221-235
    • Pascolo, S.1
  • 6
    • 0347599049 scopus 로고    scopus 로고
    • RNA sex
    • Jäschke A, Helm M. RNA sex. Chem. Biol. 10(12), 1148-1150 (2003).
    • (2003) Chem. Biol. , vol.10 , Issue.12 , pp. 1148-1150
    • Jäschke, A.1    Helm, M.2
  • 7
    • 78650640612 scopus 로고    scopus 로고
    • Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity
    • Fotin-Mleczek M, Duchardt KM, Lorenz C et al. Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity. J. Immunother. 34(1), 1-15 (2011).
    • (2011) J. Immunother. , vol.34 , Issue.1 , pp. 1-15
    • Fotin-Mleczek, M.1    Duchardt, K.M.2    Lorenz, C.3
  • 9
    • 0031671323 scopus 로고    scopus 로고
    • Human extracellular ribonucleases: Multiplicity, molecular diversity and catalytic properties of the major RNase types
    • Sorrentino S. Human extracellular ribonucleases: multiplicity, molecular diversity and catalytic properties of the major RNase types. Cell. Mol. Life Sci. CMLS 54(8), 785-794 (1998).
    • (1998) Cell. Mol. Life Sci. CMLS , vol.54 , Issue.8 , pp. 785-794
    • Sorrentino, S.1
  • 10
    • 84945574356 scopus 로고    scopus 로고
    • Progresses towards safe and effcient gene therapy vectors
    • Chira S, Jackson CS, Oprea I et al. Progresses towards safe and effcient gene therapy vectors. Oncotarget 6 (31), 30675-30703 (2015).
    • (2015) Oncotarget , vol.6 , Issue.31 , pp. 30675-30703
    • Chira, S.1    Jackson, C.S.2    Oprea, I.3
  • 11
    • 84957687437 scopus 로고    scopus 로고
    • Chemical and structural modifcations of RNAi therapeutics
    • Epub ahead of print
    • Ku SH, Jo SD, Lee YK, Kim K, Kim SH. Chemical and structural modifcations of RNAi therapeutics. Adv. Drug Deliv. Rev. doi:10.1016/j.addr.2015.10.015 (2015) (Epub ahead of print).
    • (2015) Adv. Drug Deliv. Rev
    • Ku, S.H.1    Jo, S.D.2    Lee, Y.K.3    Kim, K.4    Kim, S.H.5
  • 12
    • 80051876147 scopus 로고    scopus 로고
    • Alphaviruses in gene therapy
    • Lundstrom K. Alphaviruses in gene therapy. Viruses 1(1), 13-25 (2009).
    • (2009) Viruses , vol.1 , Issue.1 , pp. 13-25
    • Lundstrom, K.1
  • 13
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferring-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • Ogris M, Brunner S, Schüller S, Kircheis R, Wagner E. PEGylated DNA/transferring-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther. 6(4), 595-605 (1999).
    • (1999) Gene Ther. , vol.6 , Issue.4 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schüller, S.3    Kircheis, R.4    Wagner, E.5
  • 14
    • 5444275097 scopus 로고    scopus 로고
    • Immune responses to gene therapy vectors: Infuence on vector function and effector mechanisms
    • Bessis N, GarciaCozar FJ, Boissier M-C. Immune responses to gene therapy vectors: infuence on vector function and effector mechanisms. Gene Ther. 11(S1), S10-S17 (2004).
    • (2004) Gene Ther. , vol.11 , Issue.S1 , pp. S10-S17
    • Bessis, N.1    GarciaCozar, F.J.2    Boissier, M.-C.3
  • 15
    • 33645451483 scopus 로고    scopus 로고
    • Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors
    • Baum C, Kustikova O, Modlich U, Li Z, Fehse B. Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors. Hum. Gene Ther. 17(3), 253-263 (2006).
    • (2006) Hum. Gene Ther. , vol.17 , Issue.3 , pp. 253-263
    • Baum, C.1    Kustikova, O.2    Modlich, U.3    Li, Z.4    Fehse, B.5
  • 16
    • 34447535345 scopus 로고    scopus 로고
    • Engineering targeted viral vectors for gene therapy
    • Waehler R, Russell SJ, Curiel DT. Engineering targeted viral vectors for gene therapy. Nat. Rev. Genet. 8(8), 573-587 (2007).
    • (2007) Nat. Rev. Genet. , vol.8 , Issue.8 , pp. 573-587
    • Waehler, R.1    Russell, S.J.2    Curiel, D.T.3
  • 17
    • 0038745599 scopus 로고    scopus 로고
    • Progress and problems with the use of viral vectors for gene therapy
    • Thomas CE, Ehrhardt A, Kay MA. Progress and problems with the use of viral vectors for gene therapy. Nat. Rev. Genet. 4(5), 346-358 (2003).
    • (2003) Nat. Rev. Genet. , vol.4 , Issue.5 , pp. 346-358
    • Thomas, C.E.1    Ehrhardt, A.2    Kay, M.A.3
  • 18
    • 68549087056 scopus 로고    scopus 로고
    • Viral vectors: From virology to transgene expression
    • Bouard D, Alazard-Dany N, Cosset F-L. Viral vectors: from virology to transgene expression. Br. J. Pharmacol. 157(2), 153-165 (2009).
    • (2009) Br. J. Pharmacol. , vol.157 , Issue.2 , pp. 153-165
    • Bouard, D.1    Alazard-Dany, N.2    Cosset, F.-L.3
  • 19
    • 0033231242 scopus 로고    scopus 로고
    • New class of polymers for the delivery of macromolecular therapeutics
    • Gonzalez H, Hwang SJ, Davis ME. New class of polymers for the delivery of macromolecular therapeutics. Bioconjug. Chem. 10 (6), 1068-1074 (1999).
    • (1999) Bioconjug. Chem. , vol.10 , Issue.6 , pp. 1068-1074
    • Gonzalez, H.1    Hwang, S.J.2    Davis, M.E.3
  • 20
    • 67249128859 scopus 로고    scopus 로고
    • The First Targeted Delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic
    • Davis ME. The First Targeted Delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic. Mol. Pharm. 6(3), 659-668 (2009).
    • (2009) Mol. Pharm. , vol.6 , Issue.3 , pp. 659-668
    • Davis, M.E.1
  • 21
    • 84873853768 scopus 로고    scopus 로고
    • Biomolecular coronas provide the biological identity of nanosized materials
    • Monopoli MP, Åberg C, Salvati A, Dawson KA. Biomolecular coronas provide the biological identity of nanosized materials. Nat. Nanotechnol. 7(12), 779-786 (2012).
    • (2012) Nat. Nanotechnol. , vol.7 , Issue.12 , pp. 779-786
    • Monopoli, M.P.1    Åberg, C.2    Salvati, A.3    Dawson, K.A.4
  • 22
    • 84863726330 scopus 로고    scopus 로고
    • Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery
    • Lee H, Lytton-Jean AKR, Chen Y et al. Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nat. Nanotechnol. 7(6), 389-393 (2012).
    • (2012) Nat. Nanotechnol. , vol.7 , Issue.6 , pp. 389-393
    • Lee, H.1    Akr, L.2    Chen, Y.3
  • 23
    • 64549134676 scopus 로고    scopus 로고
    • Nonviral vectors for gene delivery
    • Mintzer MA, Simanek EE. Nonviral vectors for gene delivery. Chem. Rev. 109(2), 259-302 (2009).
    • (2009) Chem. Rev. , vol.109 , Issue.2 , pp. 259-302
    • Ma, M.1    Simanek, E.E.2
  • 25
    • 33847192134 scopus 로고    scopus 로고
    • Peptide-guided gene delivery
    • Martin ME, Rice KG. Peptide-guided gene delivery. AAPS J. 9(1), E18-E29 (2007).
    • (2007) AAPS J. , vol.9 , Issue.1 , pp. E18-E29
    • Martin, M.E.1    Rice, K.G.2
  • 26
    • 39849106393 scopus 로고    scopus 로고
    • Inorganic nanoparticles as carriers of nucleic acids into cells
    • Sokolova V, Epple M. Inorganic nanoparticles as carriers of nucleic acids into cells. Angew. Chem. Int. Ed. 47(8), 1382-1395 (2008).
    • (2008) Angew. Chem. Int. Ed. , vol.47 , Issue.8 , pp. 1382-1395
    • Sokolova, V.1    Epple, M.2
  • 28
    • 0035525290 scopus 로고    scopus 로고
    • Cross-presentation in viral immunity and self-tolerance
    • Heath WR, Carbone FR. Cross-presentation in viral immunity and self-tolerance. Nat. Rev. Immunol. 1(2), 126-134 (2001).
    • (2001) Nat. Rev. Immunol. , vol.1 , Issue.2 , pp. 126-134
    • Heath, W.R.1    Carbone, F.R.2
  • 29
    • 42449129646 scopus 로고    scopus 로고
    • Cross-presentation: Avoiding traffcking chaos?
    • Kasturi SP, Pulendran B. Cross-presentation: avoiding traffcking chaos? Nat. Immunol. 9(5), 461-463 (2008).
    • (2008) Nat. Immunol. , vol.9 , Issue.5 , pp. 461-463
    • Kasturi, S.P.1    Pulendran, B.2
  • 30
    • 0027170483 scopus 로고
    • Induction of virus-specifc cytotoxic T lymphocytes in vivo by liposome-entrapped mRNA
    • Martinon F, Krishnan S, Lenzen G et al. Induction of virus-specifc cytotoxic T lymphocytes in vivo by liposome-entrapped mRNA. Eur. J. Immunol. 23(7), 1719-1722 (1993).
    • (1993) Eur. J. Immunol. , vol.23 , Issue.7 , pp. 1719-1722
    • Martinon, F.1    Krishnan, S.2    Lenzen, G.3
  • 31
    • 33644591595 scopus 로고    scopus 로고
    • Vaccination with mRNAs encoding tumor-associated antigens and granulocyte-macrophage colony-stimulating factor effciently primes CTL responses, but is insuffcient to overcome tolerance to a model tumor/self antigen
    • Hess PR, Boczkowski D, Nair SK, Snyder D, Gilboa E. Vaccination with mRNAs encoding tumor-associated antigens and granulocyte-macrophage colony-stimulating factor effciently primes CTL responses, but is insuffcient to overcome tolerance to a model tumor/self antigen. Cancer Immunol. Immunother. 55(6), 672-683 (2005).
    • (2005) Cancer Immunol. Immunother. , vol.55 , Issue.6 , pp. 672-683
    • Hess, P.R.1    Boczkowski, D.2    Nair, S.K.3    Snyder, D.4    Gilboa, E.5
  • 32
    • 0033231048 scopus 로고    scopus 로고
    • RNA melanoma vaccine: Induction of antitumor immunity by human glycoprotein 100 mRNA immunization
    • Zhou W-Z, Hoon DSB, Huang SKS et al. RNA melanoma vaccine: induction of antitumor immunity by human glycoprotein 100 mRNA immunization. Hum. Gene Ther. 10(16), 2719-2724 (1999).
    • (1999) Hum. Gene Ther. , vol.10 , Issue.16 , pp. 2719-2724
    • Zhou, W.-Z.1    Dsb, H.2    Sks, H.3
  • 33
    • 84871926389 scopus 로고    scopus 로고
    • Type i IFN counteracts the induction of antigen-specifc immune responses by lipid-based delivery of mRNA vaccines
    • Pollard C, Rejman J, De Haes W et al. Type I IFN counteracts the induction of antigen-specifc immune responses by lipid-based delivery of mRNA vaccines. Mol. Ther. 21(1), 251-259 (2013).
    • (2013) Mol. Ther. , vol.21 , Issue.1 , pp. 251-259
    • Pollard, C.1    Rejman, J.2    De Haes, W.3
  • 34
    • 0033989908 scopus 로고    scopus 로고
    • In vivo application of RNA leads to induction of specifc cytotoxic T lymphocytes and antibodies
    • Hoerr I, Obst R, Rammensee HG, Jung G. In vivo application of RNA leads to induction of specifc cytotoxic T lymphocytes and antibodies. Eur. J. Immunol. 30(1), 1-7 (2000).
    • (2000) Eur. J. Immunol. , vol.30 , Issue.1 , pp. 1-7
    • Hoerr, I.1    Obst, R.2    Rammensee, H.G.3    Jung, G.4
  • 35
    • 34547919965 scopus 로고    scopus 로고
    • mRNA-based cancer vaccine: Prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes
    • Mockey M, Bourseau E, Chandrashekhar V et al. mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes. Cancer Gene Ther. 14(9), 802-814 (2007).
    • (2007) Cancer Gene Ther. , vol.14 , Issue.9 , pp. 802-814
    • Mockey, M.1    Bourseau, E.2    Chandrashekhar, V.3
  • 36
    • 79960725328 scopus 로고    scopus 로고
    • Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA
    • Perche F, Benvegnu T, Berchel M et al. Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA. Nanomed. Nanotechnol. Biol. Med. 7(4), 445-453 (2011).
    • (2011) Nanomed. Nanotechnol. Biol. Med. , vol.7 , Issue.4 , pp. 445-453
    • Perche, F.1    Benvegnu, T.2    Berchel, M.3
  • 37
    • 84902097227 scopus 로고    scopus 로고
    • Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity
    • Phua KKL, Staats HF, Leong KW, Nair SK. Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity. Sci. Rep. 4, 5128 (2014).
    • (2014) Sci. Rep. , vol.4 , pp. 5128
    • Kkl, P.1    Staats, H.F.2    Leong, K.W.3    Nair, S.K.4
  • 38
    • 84865994357 scopus 로고    scopus 로고
    • Nonviral delivery of self-amplifying RNA vaccines
    • Geall AJ, Verma A, Otten GR et al. Nonviral delivery of self-amplifying RNA vaccines. Proc. Natl Acad. Sci. USA 109(36), 14604-14609 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , Issue.36 , pp. 14604-14609
    • Geall, A.J.1    Verma, A.2    Otten, G.R.3
  • 39
    • 84927176976 scopus 로고    scopus 로고
    • A cationic nanoemulsion for the delivery of next-generation RNA vaccines
    • Brito LA, Chan M, Shaw CA et al. A cationic nanoemulsion for the delivery of next-generation RNA vaccines. Mol. Ther. 22(12), 2118-2129 (2014).
    • (2014) Mol. Ther. , vol.22 , Issue.12 , pp. 2118-2129
    • Brito, L.A.1    Chan, M.2    Shaw, C.A.3
  • 40
    • 33847099637 scopus 로고    scopus 로고
    • Lipid-based nanoparticles for nucleic acid delivery
    • Li W, Jr FCS. Lipid-based nanoparticles for nucleic acid delivery. Pharm. Res. 24(3), 438-449 (2007).
    • (2007) Pharm. Res. , vol.24 , Issue.3 , pp. 438-449
    • Li, W.1
  • 41
    • 80052269043 scopus 로고    scopus 로고
    • Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems
    • Kuntsche J, Horst JC, Bunjes H. Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems. Int. J. Pharm. 417(1), 120-137 (2011).
    • (2011) Int. J. Pharm. , vol.417 , Issue.1 , pp. 120-137
    • Kuntsche, J.1    Horst, J.C.2    Bunjes, H.3
  • 42
    • 29244439986 scopus 로고    scopus 로고
    • Formation of drug-arylsulfonate complexes inside liposomes: A novel approach to improve drug retention
    • Zhigaltsev IV, Maurer N, Edwards K, Karlsson G, Cullis PR. Formation of drug-arylsulfonate complexes inside liposomes: a novel approach to improve drug retention. J. Control. Rel. 110(2), 378-386 (2006).
    • (2006) J. Control. Rel. , vol.110 , Issue.2 , pp. 378-386
    • Zhigaltsev, I.V.1    Maurer, N.2    Edwards, K.3    Karlsson, G.4    Cullis, P.R.5
  • 43
    • 84867394662 scopus 로고    scopus 로고
    • A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo
    • Sato Y, Hatakeyama H, Sakurai Y, Hyodo M, Akita H, Harashima H. A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo. J. Control. Rel. 163(3), 267-276 (2012).
    • (2012) J. Control. Rel. , vol.163 , Issue.3 , pp. 267-276
    • Sato, Y.1    Hatakeyama, H.2    Sakurai, Y.3    Hyodo, M.4    Akita, H.5    Harashima, H.6
  • 44
  • 45
    • 82955233888 scopus 로고    scopus 로고
    • Infuence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of sirna in antigen-presenting cells
    • Basha G, Novobrantseva TI, Rosin N et al. Infuence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of sirna in antigen-presenting cells. Mol. Ther. 19(12), 2186-2200 (2011).
    • (2011) Mol. Ther. , vol.19 , Issue.12 , pp. 2186-2200
    • Basha, G.1    Novobrantseva, T.I.2    Rosin, N.3
  • 46
    • 84880274434 scopus 로고    scopus 로고
    • Effciency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
    • Sahay G, Querbes W, Alabi C et al. Effciency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling. Nat. Biotechnol. 31(7), 653-658 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , Issue.7 , pp. 653-658
    • Sahay, G.1    Querbes, W.2    Alabi, C.3
  • 47
    • 76349111051 scopus 로고    scopus 로고
    • Rational design of cationic lipids for siRNA delivery
    • Semple SC, Akinc A, Chen J et al. Rational design of cationic lipids for siRNA delivery. Nat. Biotechnol. 28(2), 172-176 (2010).
    • (2010) Nat. Biotechnol. , vol.28 , Issue.2 , pp. 172-176
    • Semple, S.C.1    Akinc, A.2    Chen, J.3
  • 48
    • 84881292568 scopus 로고    scopus 로고
    • Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics
    • Maier MA, Jayaraman M, Matsuda S et al. Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics. Mol. Ther. 21(8), 1570-1578 (2013).
    • (2013) Mol. Ther. , vol.21 , Issue.8 , pp. 1570-1578
    • Ma, M.1    Jayaraman, M.2    Matsuda, S.3
  • 49
    • 84865079107 scopus 로고    scopus 로고
    • Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo
    • Jayaraman M, Ansell SM, Mui BL et al. Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo. Angew. Chem. Int. Ed. Engl. 51(34), 8529-8533 (2012).
    • (2012) Angew. Chem. Int. Ed. Engl. , vol.51 , Issue.34 , pp. 8529-8533
    • Jayaraman, M.1    Ansell, S.M.2    Mui, B.L.3
  • 50
    • 76649098887 scopus 로고    scopus 로고
    • Lipid-like materials for low-dose, in vivo gene silencing
    • Love KT, Mahon KP, Levins CG et al. Lipid-like materials for low-dose, in vivo gene silencing. Proc. Natl Acad. Sci. USA 107(5), 1864-1869 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , Issue.5 , pp. 1864-1869
    • Love, K.T.1    Kp, M.2    Levins, C.G.3
  • 51
    • 84903643579 scopus 로고    scopus 로고
    • Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
    • Whitehead KA, Dorkin JR, Vegas AJ et al. Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity. Nat. Commun. 5, 4277 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 4277
    • Whitehead, K.A.1    Dorkin, J.R.2    Vegas, A.J.3
  • 52
    • 84896519424 scopus 로고    scopus 로고
    • Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
    • Dong Y, Love KT, Dorkin JR et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. Proc. Natl Acad. Sci. USA 111(11), 3955-3960 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , Issue.11 , pp. 3955-3960
    • Dong, Y.1    Love, K.T.2    Dorkin, J.R.3
  • 53
    • 45749147834 scopus 로고    scopus 로고
    • Conformation transformation determined by different self-assembled phases in a DNA complex with cationic polyhedral oligomeric silsesquioxane lipid
    • Cui L, Chen D, Zhu L. Conformation transformation determined by different self-assembled phases in a DNA complex with cationic polyhedral oligomeric silsesquioxane lipid. ACS Nano 2(5), 921-927 (2008).
    • (2008) ACS Nano , vol.2 , Issue.5 , pp. 921-927
    • Cui, L.1    Chen, D.2    Zhu, L.3
  • 54
    • 70349396085 scopus 로고    scopus 로고
    • Mesomorphic imidazolium salts: New vectors for effcient siRNA transfection
    • Dobbs W, Heinrich B, Bourgogne C et al. Mesomorphic imidazolium salts: new vectors for effcient siRNA transfection. J. Am. Chem. Soc. 131(37), 13338-13346 (2009).
    • (2009) J. Am. Chem. Soc. , vol.131 , Issue.37 , pp. 13338-13346
    • Dobbs, W.1    Heinrich, B.2    Bourgogne, C.3
  • 55
    • 0035861658 scopus 로고    scopus 로고
    • Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the effciency of gene delivery
    • Smisterová J, Wagenaar A, Stuart MCA et al. Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the effciency of gene delivery. J. Biol. Chem. 276(50), 47615-47622 (2001).
    • (2001) J. Biol. Chem. , vol.276 , Issue.50 , pp. 47615-47622
    • Smisterová, J.1    Wagenaar, A.2    McA, S.3
  • 57
    • 27944437882 scopus 로고    scopus 로고
    • Transition from a normal to inverted cylinder for an amidine-bearing lipid/pDNA complex and its excellent transfection
    • Koiwai K, Tokuhisa K, Karinaga R et al. Transition from a normal to inverted cylinder for an amidine-bearing lipid/pDNA complex and its excellent transfection. Bioconjug. Chem. 16(6), 1349-1351 (2005).
    • (2005) Bioconjug. Chem. , vol.16 , Issue.6 , pp. 1349-1351
    • Koiwai, K.1    Tokuhisa, K.2    Karinaga, R.3
  • 58
    • 84873252557 scopus 로고    scopus 로고
    • Liposomal drug delivery systems: From concept to clinical applications
    • Allen TM, Cullis PR. Liposomal drug delivery systems: from concept to clinical applications. Adv. Drug Deliv. Rev. 65(1), 36-48 (2013).
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , Issue.1 , pp. 36-48
    • Allen, T.M.1    Cullis, P.R.2
  • 59
    • 67249105434 scopus 로고    scopus 로고
    • A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery
    • Lu JJ, Langer R, Chen J. A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery. Mol. Pharm. 6(3), 763-771 (2009).
    • (2009) Mol. Pharm. , vol.6 , Issue.3 , pp. 763-771
    • Lu, J.J.1    Langer, R.2    Chen, J.3
  • 60
    • 0029986780 scopus 로고    scopus 로고
    • Effects of cholesterol on the lamellar and the inverted hexagonal phases of dielaidoylphosphatidylethanolamine
    • Takahashi H, Sinoda K, Hatta I. Effects of cholesterol on the lamellar and the inverted hexagonal phases of dielaidoylphosphatidylethanolamine. Biochim. Biophys. Acta 1289(2), 209-216 (1996).
    • (1996) Biochim. Biophys. Acta , vol.1289 , Issue.2 , pp. 209-216
    • Takahashi, H.1    Sinoda, K.2    Hatta, I.3
  • 61
    • 17644419268 scopus 로고    scopus 로고
    • Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection effciency
    • Zuhorn IS, Bakowsky U, Polushkin E et al. Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection effciency. Mol. Ther. 11(5), 801-810 (2005).
    • (2005) Mol. Ther. , vol.11 , Issue.5 , pp. 801-810
    • Zuhorn, I.S.1    Bakowsky, U.2    Polushkin, E.3
  • 62
    • 0029360756 scopus 로고
    • Sterically stabilized liposome therapeutics
    • Woodle MC. Sterically stabilized liposome therapeutics. Adv. Drug Deliv. Rev. 16(2), 249-265 (1995).
    • (1995) Adv. Drug Deliv. Rev. , vol.16 , Issue.2 , pp. 249-265
    • Woodle, M.C.1
  • 63
    • 84868338479 scopus 로고    scopus 로고
    • Microfuidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA
    • Belliveau NM, Huft J, Lin PJ et al. Microfuidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA. Mol. Ther. Nucleic Acids 1(8), e37 (2012).
    • (2012) Mol. Ther. Nucleic Acids , vol.1 , Issue.8 , pp. e37
    • Belliveau, N.M.1    Huft, J.2    Lin, P.J.3
  • 64
    • 77954313055 scopus 로고    scopus 로고
    • Stealth nanoparticles: High density but sheddable PEG is a key for tumor targeting
    • Li S-D, Huang L. Stealth nanoparticles: high density but sheddable PEG is a key for tumor targeting. J. Control. Rel. Off. J. Control Rel. Soc. 145(3), 178-181 (2010).
    • (2010) J. Control. Rel. Off. J. Control Rel. Soc. , vol.145 , Issue.3 , pp. 178-181
    • Li, S.-D.1    Huang, L.2
  • 65
    • 84859269808 scopus 로고    scopus 로고
    • Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier design
    • Buyens K, De Smedt SC, Braeckmans K et al. Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design. J. Control Rel. 158(3), 362-370 (2012).
    • (2012) J. Control Rel. , vol.158 , Issue.3 , pp. 362-370
    • Buyens, K.1    De Smedt, S.C.2    Braeckmans, K.3
  • 66
    • 33645734929 scopus 로고    scopus 로고
    • Toll-dependent selection of microbial antigens for presentation by dendritic cells
    • Blander JM, Medzhitov R. Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature 440(7085), 808-812 (2006).
    • (2006) Nature , vol.440 , Issue.7085 , pp. 808-812
    • Blander, J.M.1    Medzhitov, R.2
  • 67
    • 40249092848 scopus 로고    scopus 로고
    • TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses
    • Schlosser E, Mueller M, Fischer S et al. TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses. Vaccine 26(13), 1626-1637 (2008).
    • (2008) Vaccine , vol.26 , Issue.13 , pp. 1626-1637
    • Schlosser, E.1    Mueller, M.2    Fischer, S.3
  • 68
    • 0024289274 scopus 로고
    • The mechanism of vesicle formation
    • Lasic DD. The mechanism of vesicle formation. Biochem. J. 256(1), 1-11 (1988).
    • (1988) Biochem. J. , vol.256 , Issue.1 , pp. 1-11
    • Lasic, D.D.1
  • 69
    • 84983573851 scopus 로고    scopus 로고
    • Solid lipid nanoparticles and nanostructured lipid carriers: Structure, preparation and application
    • Naseri N, Valizadeh H, Zakeri-Milani P. Solid lipid nanoparticles and nanostructured lipid carriers: structure, preparation and application. Adv. Pharm. Bull. 5(3), 305-313 (2015).
    • (2015) Adv. Pharm. Bull. , vol.5 , Issue.3 , pp. 305-313
    • Naseri, N.1    Valizadeh, H.2    Zakeri-Milani, P.3
  • 70
    • 84859796841 scopus 로고    scopus 로고
    • Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfuidic mixing
    • Zhigaltsev IV, Belliveau N, Hafez I et al. Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfuidic mixing. Langmuir 28(7), 3633-3640 (2012).
    • (2012) Langmuir , vol.28 , Issue.7 , pp. 3633-3640
    • Zhigaltsev, I.V.1    Belliveau, N.2    Hafez, I.3
  • 71
    • 0014441009 scopus 로고
    • Phosphatidylcholine vesicles. Formation and physical characteristics
    • Huang C-H. Phosphatidylcholine vesicles. Formation and physical characteristics. Biochemistry (Mosc.) 8(1), 344-352 (1969).
    • (1969) Biochemistry (Mosc.) , vol.8 , Issue.1 , pp. 344-352
    • Huang, C.-H.1
  • 72
    • 0015927357 scopus 로고
    • Single bilayer liposomes prepared without sonication
    • Batzri S, Korn ED. Single bilayer liposomes prepared without sonication. Biochim. Biophys. Acta BBA-Biomembr. 298(4), 1015-1019 (1973).
    • (1973) Biochim. Biophys. Acta BBA-Biomembr. , vol.298 , Issue.4 , pp. 1015-1019
    • Batzri, S.1    Korn, E.D.2
  • 73
    • 0035830624 scopus 로고    scopus 로고
    • Effcient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: Formation of novel small multilamellar vesicle structures
    • Semple SC, Klimuk SK, Harasym TO et al. Effcient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures. Biochim. Biophys. Acta BBA-Biomembr. 1510(1), 152-166 (2001).
    • (2001) Biochim. Biophys. Acta BBA-Biomembr. , vol.1510 , Issue.1 , pp. 152-166
    • Semple, S.C.1    Klimuk, S.K.2    Harasym, T.O.3
  • 74
    • 0035039280 scopus 로고    scopus 로고
    • Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes
    • Maurer N, Wong KF, Stark H et al. Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes. Biophys. J. 80(5), 2310-2326 (2001).
    • (2001) Biophys. J. , vol.80 , Issue.5 , pp. 2310-2326
    • Maurer, N.1    Wong, K.F.2    Stark, H.3
  • 75
    • 0035979414 scopus 로고    scopus 로고
    • Filter extrusion of liposomes using different devices: Comparison of liposome size, encapsulation effciency, and process characteristics
    • Berger N, Sachse A, Bender J, Schubert R, Brandl M. Filter extrusion of liposomes using different devices: comparison of liposome size, encapsulation effciency, and process characteristics. Int. J. Pharm. 223(1), 55-68 (2001).
    • (2001) Int. J. Pharm. , vol.223 , Issue.1 , pp. 55-68
    • Berger, N.1    Sachse, A.2    Bender, J.3    Schubert, R.4    Brandl, M.5
  • 77
    • 54549109219 scopus 로고    scopus 로고
    • Microfuidic platform for controlled synthesis of polymeric nanoparticles
    • Karnik R, Gu F, Basto P et al. Microfuidic platform for controlled synthesis of polymeric nanoparticles. Nano Lett. 8(9), 2906-2912 (2008).
    • (2008) Nano Lett. , vol.8 , Issue.9 , pp. 2906-2912
    • Karnik, R.1    Gu, F.2    Basto, P.3
  • 78
    • 34249977091 scopus 로고    scopus 로고
    • Microfuidic directed formation of liposomes of controlled size
    • Jahn A, Vreeland WN, DeVoe DL, Locascio LE, Gaitan M. Microfuidic directed formation of liposomes of controlled size. Langmuir 23(11), 6289-6293 (2007).
    • (2007) Langmuir , vol.23 , Issue.11 , pp. 6289-6293
    • Jahn, A.1    Vreeland, W.N.2    DeVoe, D.L.3    Locascio, L.E.4    Gaitan, M.5
  • 80
    • 84937135320 scopus 로고    scopus 로고
    • Microfuidic mixing: A general method for encapsulating macromolecules in lipid nanoparticle systems
    • Leung AKK, Tam YYC, Chen S, Hafez IM, Cullis PR. Microfuidic mixing: a general method for encapsulating macromolecules in lipid nanoparticle systems. J. Phys. Chem. B 119(28), 8698-8706 (2015).
    • (2015) J. Phys. Chem. B , vol.119 , Issue.28 , pp. 8698-8706
    • Akk, L.1    Yyc, T.2    Chen, S.3    Hafez, I.M.4    Cullis, P.R.5
  • 81
    • 0035940071 scopus 로고    scopus 로고
    • The physiology of the lymphatic system
    • Swartz MA. The physiology of the lymphatic system. Adv. Drug Deliv. Rev. 50(1), 3-20 (2001).
    • (2001) Adv. Drug Deliv. Rev. , vol.50 , Issue.1 , pp. 3-20
    • Swartz, M.A.1
  • 82
    • 0027220849 scopus 로고
    • Subcutaneous administration of liposomes: A comparison with the intravenous and intraperitoneal routes of injection
    • Allen TM, Hansen CB, Guo LSS. Subcutaneous administration of liposomes: a comparison with the intravenous and intraperitoneal routes of injection. Biochim. Biophys. Acta BBA-Biomembr. 1150(1), 9-16 (1993).
    • (1993) Biochim. Biophys. Acta BBA-Biomembr. , vol.1150 , Issue.1 , pp. 9-16
    • Allen, T.M.1    Hansen, C.B.2    Guo, L.S.S.3
  • 84
    • 76749160185 scopus 로고    scopus 로고
    • Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen
    • Henriksen-Lacey M, Bramwell VW, Christensen D, Agger E-M, Andersen P, Perrie Y. Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen. J. Control. Rel. 142(2), 180-186 (2010).
    • (2010) J. Control. Rel. , vol.142 , Issue.2 , pp. 180-186
    • Henriksen-Lacey, M.1    Bramwell, V.W.2    Christensen, D.3    Agger, E.-M.4    Andersen, P.5    Perrie, Y.6
  • 85
    • 79952968002 scopus 로고    scopus 로고
    • Comparison of the depot effect and immunogenicity of liposomes based on dimethyldioctadecylammonium (DDA), 3β-[n-(n′, n′-dimethylaminoethane)carbomyl], cholesterol (DC-Chol), and 1, 2-dioleoyl-3-trimethylammonium propane (dotap): Prolonged liposome retention mediates stronger Th1 responses
    • Henriksen-Lacey M, Christensen D, Bramwell VW et al. Comparison of the depot effect and immunogenicity of liposomes based on dimethyldioctadecylammonium (DDA), 3β-[n-(n′, n′-dimethylaminoethane)carbomyl], cholesterol (DC-Chol), and 1, 2-dioleoyl-3-trimethylammonium propane (dotap): prolonged liposome retention mediates stronger Th1 responses. Mol. Pharm. 8(1), 153-161 (2011).
    • (2011) Mol. Pharm. , vol.8 , Issue.1 , pp. 153-161
    • Henriksen-Lacey, M.1    Christensen, D.2    Bramwell, V.W.3
  • 87
    • 79960635999 scopus 로고    scopus 로고
    • Effect of vesicle size on tissue localization and immunogenicity of liposomal DNA vaccines
    • Carstens MG, Camps MGM, Henriksen-Lacey M et al. Effect of vesicle size on tissue localization and immunogenicity of liposomal DNA vaccines. Vaccine 29(29), 4761-4770 (2011).
    • (2011) Vaccine , vol.29 , Issue.29 , pp. 4761-4770
    • Carstens, M.G.1    Mgm, C.2    Henriksen-Lacey, M.3
  • 88
    • 84857913863 scopus 로고    scopus 로고
    • Pegylation of DDA:TDB liposomal adjuvants reduces the vaccine depot effect and alters the Th1/Th2 immune responses
    • Kaur R, Bramwell VW, Kirby DJ, Perrie Y. Pegylation of DDA:TDB liposomal adjuvants reduces the vaccine depot effect and alters the Th1/Th2 immune responses. J. Control Rel. 158(1), 72-77 (2012).
    • (2012) J. Control Rel. , vol.158 , Issue.1 , pp. 72-77
    • Kaur, R.1    Bramwell, V.W.2    Kirby, D.J.3    Perrie, Y.4
  • 89
    • 72149108423 scopus 로고    scopus 로고
    • Shielding the cationic charge of nanoparticle-formulated dermal DNA vaccines is essential for antigen expression and immunogenicity
    • van den Berg JH, Oosterhuis K, Hennink WE et al. Shielding the cationic charge of nanoparticle-formulated dermal DNA vaccines is essential for antigen expression and immunogenicity. J. Control Rel. 141(2), 234-240 (2010).
    • (2010) J. Control Rel. , vol.141 , Issue.2 , pp. 234-240
    • Van Den Berg, J.H.1    Oosterhuis, K.2    Hennink, W.E.3
  • 90
    • 2942632966 scopus 로고    scopus 로고
    • PEGylation signifcantly affects cellular uptake and intracellular traffcking of non-viral gene delivery particles
    • Mishra S, Webster P, Davis ME. PEGylation signifcantly affects cellular uptake and intracellular traffcking of non-viral gene delivery particles. Eur. J. Cell Biol. 83 (3), 97-111 (2004).
    • (2004) Eur. J. Cell Biol. , vol.83 , Issue.3 , pp. 97-111
    • Mishra, S.1    Webster, P.2    Davis, M.E.3
  • 91
    • 33846493607 scopus 로고    scopus 로고
    • Pegylation of liposomes favours the endosomal degradation of the delivered phosphodiester oligonucleotides
    • Remaut K, Lucas B, Braeckmans K, Demeester J, De Smedt SC. Pegylation of liposomes favours the endosomal degradation of the delivered phosphodiester oligonucleotides. J. Control Rel. 117(2), 256-266 (2007).
    • (2007) J. Control Rel. , vol.117 , Issue.2 , pp. 256-266
    • Remaut, K.1    Lucas, B.2    Braeckmans, K.3    Demeester, J.4    De Smedt, S.C.5
  • 92
    • 84937800081 scopus 로고    scopus 로고
    • Anti-PEG immunity: Emergence, characteristics, and unaddressed questions
    • Yang Q, Lai SK. Anti-PEG immunity: emergence, characteristics, and unaddressed questions. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 7(5), 655-677 (2015).
    • (2015) Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. , vol.7 , Issue.5 , pp. 655-677
    • Yang, Q.1    Lai, S.K.2
  • 93
    • 30344454418 scopus 로고    scopus 로고
    • Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes
    • Judge A, McClintock K, Phelps JR, MacLachlan I. Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes. Mol. Ther. 13(2), 328-337 (2006).
    • (2006) Mol. Ther. , vol.13 , Issue.2 , pp. 328-337
    • Judge, A.1    McClintock, K.2    Phelps, J.R.3    MacLachlan, I.4
  • 94
    • 84870430539 scopus 로고    scopus 로고
    • The mannose receptor
    • Martinez-Pomares L. The mannose receptor. J. Leukoc. Biol. 92 (6), 1177-1186 (2012).
    • (2012) J. Leukoc. Biol. , vol.92 , Issue.6 , pp. 1177-1186
    • Martinez-Pomares, L.1
  • 95
    • 0034598934 scopus 로고    scopus 로고
    • Identifcation of DC-SIGN, a novel dendritic cell-specifc ICAM-3 receptor that supports primary immune responses
    • Geijtenbeek TBH, Torensma R, van Vliet SJ et al. Identifcation of DC-SIGN, a novel dendritic cell-specifc ICAM-3 receptor that supports primary immune responses. Cell 100(5), 575-585 (2000).
    • (2000) Cell , vol.100 , Issue.5 , pp. 575-585
    • Tbh, G.1    Torensma, R.2    Van Vliet, S.J.3
  • 96
    • 0029009977 scopus 로고
    • The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
    • Jiang W, Swiggard WJ, Heufer C et al. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375 (6527), 151-155 (1995).
    • (1995) Nature , vol.375 , Issue.6527 , pp. 151-155
    • Jiang, W.1    Swiggard, W.J.2    Heufer, C.3
  • 97
    • 0033984930 scopus 로고    scopus 로고
    • Langerin, a novel C-Type lectin specifc to langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules
    • Valladeau J, Ravel O, Dezutter-Dambuyant C et al. Langerin, a novel C-Type lectin specifc to langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Immunity 12(1), 71-81 (2000).
    • (2000) Immunity , vol.12 , Issue.1 , pp. 71-81
    • Valladeau, J.1    Ravel, O.2    Dezutter-Dambuyant, C.3
  • 98
    • 0031457133 scopus 로고    scopus 로고
    • Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein
    • Karanikas V, Hwang LA, Pearson J et al. Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein. J. Clin. Invest. 100(11), 2783-2792 (1997).
    • (1997) J. Clin. Invest. , vol.100 , Issue.11 , pp. 2783-2792
    • Karanikas, V.1    Hwang, L.A.2    Pearson, J.3
  • 99
    • 58149085979 scopus 로고    scopus 로고
    • Infuence of ligand valency on the targeting of immature human dendritic cells by mannosylated liposomes
    • Espuelas S, Thumann C, Heurtault B, Schuber F, Frisch B. Infuence of ligand valency on the targeting of immature human dendritic cells by mannosylated liposomes. Bioconjug. Chem. 19(12), 2385-2393 (2008).
    • (2008) Bioconjug. Chem. , vol.19 , Issue.12 , pp. 2385-2393
    • Espuelas, S.1    Thumann, C.2    Heurtault, B.3    Schuber, F.4    Frisch, B.5
  • 100
    • 84884788108 scopus 로고    scopus 로고
    • Glycodendritic structures: Tools to interact with DC-SIGN
    • SPE
    • Reina JJ, Rojo J. Glycodendritic structures: tools to interact with DC-SIGN. Braz. J. Pharm. Sci. 49(SPE), 109-124 (2013).
    • (2013) Braz. J. Pharm. Sci. , vol.49 , pp. 109-124
    • Reina, J.J.1    Rojo, J.2
  • 101
    • 79955608038 scopus 로고    scopus 로고
    • Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes
    • Perche F, Gosset D, Mével M et al. Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes. J. Drug Target. 19(5), 315-325 (2011).
    • (2011) J. Drug Target. , vol.19 , Issue.5 , pp. 315-325
    • Perche, F.1    Gosset, D.2    Mével, M.3
  • 102
    • 33846636409 scopus 로고    scopus 로고
    • Differential antigen processing by dendritic cell subsets in vivo
    • Dudziak D, Kamphorst AO, Heidkamp GF et al. Differential antigen processing by dendritic cell subsets in vivo. Science 315(5808), 107-111 (2007).
    • (2007) Science , vol.315 , Issue.5808 , pp. 107-111
    • Dudziak, D.1    Kamphorst, A.O.2    Heidkamp, G.F.3
  • 103
    • 77955597687 scopus 로고    scopus 로고
    • Unmet needs in modern vaccinology: Adjuvants to improve the immune response
    • Leroux-Roels G. Unmet needs in modern vaccinology: adjuvants to improve the immune response. Vaccine 28(Suppl. 3), C25-C36 (2010).
    • (2010) Vaccine , vol.28 , pp. C25-C36
    • Leroux-Roels, G.1
  • 104
    • 34547899919 scopus 로고    scopus 로고
    • Solid lipid nanoparticles as a drug delivery system for peptides and proteins
    • Almeida AJ, Souto E. Solid lipid nanoparticles as a drug delivery system for peptides and proteins. Adv. Drug Deliv. Rev. 59(6), 478-490 (2007).
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , Issue.6 , pp. 478-490
    • Almeida, A.J.1    Souto, E.2
  • 105
    • 77954385672 scopus 로고    scopus 로고
    • The systemic toxicity of positively charged lipid nanoparticles and the role of Tolllike receptor 4 in immune activation
    • Kedmi R, Ben-Arie N, Peer D. The systemic toxicity of positively charged lipid nanoparticles and the role of Tolllike receptor 4 in immune activation. Biomaterials 31(26), 6867-6875 (2010).
    • (2010) Biomaterials , vol.31 , Issue.26 , pp. 6867-6875
    • Kedmi, R.1    Ben-Arie, N.2    Peer, D.3
  • 106
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34(5), 637-650 (2011).
    • (2011) Immunity , vol.34 , Issue.5 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 107
    • 79961064785 scopus 로고    scopus 로고
    • Negatively charged liposomes show potent adjuvant activity when simply admixed with protein antigens
    • Yanasarn N, Sloat BR, Cui Z. Negatively charged liposomes show potent adjuvant activity when simply admixed with protein antigens. Mol. Pharm. 8 (4), 1174-1185 (2011).
    • (2011) Mol. Pharm. , vol.8 , Issue.4 , pp. 1174-1185
    • Yanasarn, N.1    Sloat, B.R.2    Cui, Z.3
  • 108
    • 79958143955 scopus 로고    scopus 로고
    • Characterization of the murine Th2 response to immunization with liposomal M2e infuenza vaccine
    • Adler-Moore J, Munoz M, Kim H et al. Characterization of the murine Th2 response to immunization with liposomal M2e infuenza vaccine. Vaccine 29(27), 4460-4468 (2011).
    • (2011) Vaccine , vol.29 , Issue.27 , pp. 4460-4468
    • Adler-Moore, J.1    Munoz, M.2    Kim, H.3
  • 109
    • 84855461418 scopus 로고    scopus 로고
    • Vaccination with liposomal leishmanial antigens adjuvanted with monophosphoryl lipid-trehalose dicorynomycolate (MPL-TDM) confers long-term protection against visceral leishmaniasis through a human administrable route
    • Ravindran R, Maji M, Ali N. Vaccination with liposomal leishmanial antigens adjuvanted with monophosphoryl lipid-trehalose dicorynomycolate (MPL-TDM) confers long-term protection against visceral leishmaniasis through a human administrable route. Mol. Pharm. 9(1), 59-70 (2012).
    • (2012) Mol. Pharm. , vol.9 , Issue.1 , pp. 59-70
    • Ravindran, R.1    Maji, M.2    Ali, N.3
  • 110
    • 84869885729 scopus 로고    scopus 로고
    • Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses
    • Rizwan SB, McBurney WT, Young K et al. Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses. J. Control Rel. 165(1), 16-21 (2013).
    • (2013) J. Control Rel. , vol.165 , Issue.1 , pp. 16-21
    • Rizwan, S.B.1    McBurney, W.T.2    Young, K.3
  • 111
    • 84893053165 scopus 로고    scopus 로고
    • Recent progress concerning CpG DNA and its use as a vaccine adjuvant
    • Shirota H, Klinman DM. Recent progress concerning CpG DNA and its use as a vaccine adjuvant. Exp. Rev. Vaccines 13(2), 299-312 (2014).
    • (2014) Exp. Rev. Vaccines , vol.13 , Issue.2 , pp. 299-312
    • Shirota, H.1    Klinman, D.M.2
  • 112
    • 78650305541 scopus 로고    scopus 로고
    • Differential immune activation following encapsulation of immunostimulatory CpG oligodeoxynucleotide in nanoliposomes
    • Erikçi E, Gursel M, Gürsel I. Differential immune activation following encapsulation of immunostimulatory CpG oligodeoxynucleotide in nanoliposomes. Biomaterials 32(6), 1715-1723 (2011).
    • (2011) Biomaterials , vol.32 , Issue.6 , pp. 1715-1723
    • Erikçi, E.1    Gursel, M.2    Gürsel, I.3
  • 113
    • 78751574293 scopus 로고    scopus 로고
    • Co-encapsulation of antigen and Toll-like receptor ligand in cationic liposomes affects the quality of the immune response in mice after intradermal vaccination
    • Bal SM, Hortensius S, Ding Z, Jiskoot W, Bouwstra JA. Co-encapsulation of antigen and Toll-like receptor ligand in cationic liposomes affects the quality of the immune response in mice after intradermal vaccination. Vaccine 29(5), 1045-1052 (2011).
    • (2011) Vaccine , vol.29 , Issue.5 , pp. 1045-1052
    • Bal, S.M.1    Hortensius, S.2    Ding, Z.3    Jiskoot, W.4    Bouwstra, J.A.5
  • 114
    • 84911911677 scopus 로고    scopus 로고
    • Rational design of small molecules as vaccine adjuvants
    • Wu TY-H, Singh M, Miller AT et al. Rational design of small molecules as vaccine adjuvants. Sci. Transl. Med. 6(263), 263ra160-263ra160 (2014).
    • (2014) Sci. Transl. Med. , vol.6 , Issue.263 , pp. 263ra160-263ra160
    • Ty-H, W.1    Singh, M.2    Miller, A.T.3
  • 115
    • 84857969026 scopus 로고    scopus 로고
    • Sensing of RNA viruses: A review of innate immune receptors involved in recognizing RNA virus invasion
    • Jensen S, Thomsen AR. Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion. J. Virol. 86(6), 2900-2910 (2012).
    • (2012) J. Virol. , vol.86 , Issue.6 , pp. 2900-2910
    • Jensen, S.1    Thomsen, A.R.2
  • 116
    • 84921794613 scopus 로고    scopus 로고
    • mRNA-based therapeutics-developing a new class of drugs
    • Sahin U, Karikó K, Türeci Ö. mRNA-based therapeutics-developing a new class of drugs. Nat. Rev. Drug Discov. 13(10), 759-780 (2014).
    • (2014) Nat. Rev. Drug Discov. , vol.13 , Issue.10 , pp. 759-780
    • Sahin, U.1    Karikó, K.2    Türeci, Ö.3
  • 117
    • 0033679958 scopus 로고    scopus 로고
    • Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection
    • Balachandran S, Roberts PC, Brown LE et al. Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection. Immunity 13(1), 129-141 (2000).
    • (2000) Immunity , vol.13 , Issue.1 , pp. 129-141
    • Balachandran, S.1    Roberts, P.C.2    Brown, L.E.3
  • 118
    • 84899734649 scopus 로고    scopus 로고
    • Cell-type-specifc effects of RNase L on viral induction of beta interferon
    • Banerjee S, Chakrabarti A, Jha BK et al. Cell-type-specifc effects of RNase L on viral induction of beta interferon. mBio 5(2), e00856-e00814 (2014); doi: 10.1128/mBio.00856-14.
    • (2014) MBio , vol.5 , Issue.2 , pp. e00856-e00864
    • Banerjee, S.1    Chakrabarti, A.2    Jha, B.K.3
  • 119
    • 23844464444 scopus 로고    scopus 로고
    • Suppression of RNA recognition by toll-like receptors: The impact of nucleoside modifcation and the evolutionary origin of RNA
    • Karikó K, Buckstein M, Ni H, Weissman D. Suppression of RNA recognition by toll-like receptors: the impact of nucleoside modifcation and the evolutionary origin of RNA. Immunity 23 (2), 165-175 (2005).
    • (2005) Immunity , vol.23 , Issue.2 , pp. 165-175
    • Karikó, K.1    Buckstein, M.2    Ni, H.3    Weissman, D.4
  • 120
    • 54949112814 scopus 로고    scopus 로고
    • Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability
    • Karikó K, Muramatsu H, Welsh FA et al. Incorporation of pseudouridine into mrna yields superior nonimmunogenic vector with increased translational capacity and biological stability. Mol. Ther. J. Am. Soc. Gene Ther. 16(11), 1833-1840 (2008).
    • (2008) Mol. Ther. J. Am. Soc. Gene Ther. , vol.16 , Issue.11 , pp. 1833-1840
    • Karikó, K.1    Muramatsu, H.2    Welsh, F.A.3
  • 121
    • 84997666967 scopus 로고    scopus 로고
    • Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: A frst-in-man Phase I/IIa study
    • Kübler H, Scheel B, Gnad-Vogt U et al. Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a frst-in-man Phase I/IIa study. J. Immunother. Cancer 3(1), 26 (2015).
    • (2015) J. Immunother. Cancer , vol.3 , Issue.1 , pp. 26
    • Kübler, H.1    Scheel, B.2    Gnad-Vogt, U.3
  • 122
    • 84893093837 scopus 로고    scopus 로고
    • Human vaccines and immunotherapeutics
    • Riedmann EM. Human vaccines and immunotherapeutics. Hum. Vaccines Immunother. 9(10), 2034-2037 (2013).
    • (2013) Hum. Vaccines Immunother. , vol.9 , Issue.10 , pp. 2034-2037
    • Riedmann, E.M.1
  • 123
    • 0024559617 scopus 로고
    • Translation initiation at non-AUG triplets in mammalian cells
    • Peabody DS. Translation initiation at non-AUG triplets in mammalian cells. J. Biol. Chem. 264(9), 5031-5035 (1989).
    • (1989) J. Biol. Chem. , vol.264 , Issue.9 , pp. 5031-5035
    • Peabody, D.S.1
  • 124
    • 0033151592 scopus 로고    scopus 로고
    • Presentation of out-of-frame peptide/MHC Class i complexes by a novel translation initiation mechanism
    • Malarkannan S, Horng T, Shih PP, Schwab S, Shastri N. Presentation of out-of-frame peptide/MHC Class I complexes by a novel translation initiation mechanism. Immunity 10(6), 681-690 (1999).
    • (1999) Immunity , vol.10 , Issue.6 , pp. 681-690
    • Malarkannan, S.1    Horng, T.2    Shih, P.P.3    Schwab, S.4    Shastri, N.5
  • 125
    • 84908701702 scopus 로고    scopus 로고
    • A critical analysis of codon optimization in human therapeutics
    • Mauro VP, Chappell SA. A critical analysis of codon optimization in human therapeutics. Trends Mol. Med. 20(11), 604-613 (2014).
    • (2014) Trends Mol. Med. , vol.20 , Issue.11 , pp. 604-613
    • Mauro, V.P.1    Chappell, S.A.2
  • 126
    • 0028055226 scopus 로고
    • Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes
    • Litzinger DC, Buiting AMJ, van Rooijen N, Huang L. Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes. Biochim. Biophys. Acta BBA-Biomembr. 1190(1), 99-107 (1994).
    • (1994) Biochim. Biophys. Acta BBA-Biomembr. , vol.1190 , Issue.1 , pp. 99-107
    • Litzinger, D.C.1    Amj, B.2    Van Rooijen, N.3    Huang, L.4
  • 127
    • 78049288264 scopus 로고    scopus 로고
    • Vaccine delivery: A matter of size, geometry, kinetics and molecular patterns
    • Bachmann MF, Jennings GT. Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns. Nat. Rev. Immunol. 10(11), 787-796 (2010).
    • (2010) Nat. Rev. Immunol. , vol.10 , Issue.11 , pp. 787-796
    • Bachmann, M.F.1    Jennings, G.T.2
  • 128
    • 33646480406 scopus 로고    scopus 로고
    • In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfde) nanoparticles
    • Reddy ST, Rehor A, Schmoekel HG, Hubbell JA, Swartz MA. In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfde) nanoparticles. J. Control Rel. 112(1), 26-34 (2006).
    • (2006) J. Control Rel. , vol.112 , Issue.1 , pp. 26-34
    • Reddy, S.T.1    Rehor, A.2    Schmoekel, H.G.3    Hubbell, J.A.4    Swartz, M.A.5
  • 129
    • 47049100427 scopus 로고    scopus 로고
    • Nanoparticles target distinct dendritic cell populations according to their size
    • Manolova V, Flace A, Bauer M, Schwarz K, Saudan P, Bachmann MF. Nanoparticles target distinct dendritic cell populations according to their size. Eur. J. Immunol. 38(5), 1404-1413 (2008).
    • (2008) Eur. J. Immunol. , vol.38 , Issue.5 , pp. 1404-1413
    • Manolova, V.1    Flace, A.2    Bauer, M.3    Schwarz, K.4    Saudan, P.5    Bachmann, M.F.6
  • 130
    • 84921357504 scopus 로고    scopus 로고
    • Lipid-based mRNA vaccine delivery systems
    • Midoux P, Pichon C. Lipid-based mRNA vaccine delivery systems. Expert Rev. Vaccines 14(2), 221-234 (2015).
    • (2015) Expert Rev. Vaccines , vol.14 , Issue.2 , pp. 221-234
    • Midoux, P.1    Pichon, C.2
  • 132
    • 1342268100 scopus 로고    scopus 로고
    • Use of the inactivated intranasal infuenza vaccine and the risk of Bell's palsy in Switzerland
    • Mutsch M, Zhou W, Rhodes P et al. Use of the inactivated intranasal infuenza vaccine and the risk of Bell's palsy in Switzerland. N. Engl. J. Med. 350(9), 896-903 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , Issue.9 , pp. 896-903
    • Mutsch, M.1    Zhou, W.2    Rhodes, P.3
  • 133
    • 78549283854 scopus 로고    scopus 로고
    • Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity
    • Kreiter S, Selmi A, Diken M et al. Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity. Cancer Res. 70(22), 9031-9040 (2010).
    • (2010) Cancer Res. , vol.70 , Issue.22 , pp. 9031-9040
    • Kreiter, S.1    Selmi, A.2    Diken, M.3
  • 134
    • 0037664871 scopus 로고    scopus 로고
    • Phase i study of intranodal delivery of a plasmid DNA vaccine for patients with stage IV melanoma
    • Tagawa ST, Lee P, Snively J et al. Phase I study of intranodal delivery of a plasmid DNA vaccine for patients with stage IV melanoma. Cancer 98(1), 144-154 (2003).
    • (2003) Cancer , vol.98 , Issue.1 , pp. 144-154
    • Tagawa, S.T.1    Lee, P.2    Snively, J.3
  • 135
    • 84945466813 scopus 로고    scopus 로고
    • Expression kinetics of nucleoside-modifed mRNA delivered in lipid nanoparticles to mice by various routes
    • Pardi N, Tuyishime S, Muramatsu H et al. Expression kinetics of nucleoside-modifed mRNA delivered in lipid nanoparticles to mice by various routes. J. Control Rel. 217, 345-351 (2015).
    • (2015) J. Control Rel. , vol.217 , pp. 345-351
    • Pardi, N.1    Tuyishime, S.2    Muramatsu, H.3
  • 136
    • 84908239334 scopus 로고    scopus 로고
    • Self-amplifying replicon RNA vaccine delivery to dendritic cells by synthetic nanoparticles
    • McCullough KC, Milona P, Thomann-Harwood L et al. Self-amplifying replicon RNA vaccine delivery to dendritic cells by synthetic nanoparticles. Vaccines 2(4), 735-754 (2014).
    • (2014) Vaccines , vol.2 , Issue.4 , pp. 735-754
    • McCullough, K.C.1    Milona, P.2    Thomann-Harwood, L.3
  • 138
    • 0031583842 scopus 로고    scopus 로고
    • Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: Expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo
    • Pushko P, Parker M, Ludwig GV, Davis NL, Johnston RE, Smith JF. Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Virology 239(2), 389-401 (1997).
    • (1997) Virology , vol.239 , Issue.2 , pp. 389-401
    • Pushko, P.1    Parker, M.2    Ludwig, G.V.3    Davis, N.L.4    Johnston, R.E.5    Smith, J.F.6
  • 140
    • 67651152679 scopus 로고    scopus 로고
    • Direct injection of protamine-protected mRNA: Results of a Phase 1/2 vaccination trial in metastatic melanoma patients
    • Weide B, Pascolo S, Scheel B et al. Direct injection of protamine-protected mRNA: results of a Phase 1/2 vaccination trial in metastatic melanoma patients. J. Immunother. 32(5), 498-507 (2009).
    • (2009) J. Immunother. , vol.32 , Issue.5 , pp. 498-507
    • Weide, B.1    Pascolo, S.2    Scheel, B.3
  • 141
    • 84938632589 scopus 로고    scopus 로고
    • Lipid-based nanocarriers for RNA delivery
    • Xue HY, Guo P, Wen W-C, Wong HL. Lipid-based nanocarriers for RNA delivery. Curr. Pharm. Des. 21(22), 3140-3147 (2015).
    • (2015) Curr. Pharm. Des. , vol.21 , Issue.22 , pp. 3140-3147
    • Xue, H.Y.1    Guo, P.2    Wen, W.-C.3    Wong, H.L.4
  • 142
    • 84946962398 scopus 로고    scopus 로고
    • Optimization of lipid nanoparticle formulations for mRNA delivery in vivo with fractional factorial and defnitive screening designs
    • Kauffman KJ, Dorkin JR, Yang JH et al. Optimization of lipid nanoparticle formulations for mRNA delivery in vivo with fractional factorial and defnitive screening designs. Nano Lett. 15(11), 7300-7306 (2015).
    • (2015) Nano Lett. , vol.15 , Issue.11 , pp. 7300-7306
    • Kauffman, K.J.1    Dorkin, J.R.2    Yang, J.H.3
  • 143
    • 0005457558 scopus 로고    scopus 로고
    • First human trial of a DNA-based vaccine for treatment of human immunodefciency virus type 1 infection: Safety and host response
    • MacGregor RR, Boyer JD, Ugen KE et al. First human trial of a DNA-based vaccine for treatment of human immunodefciency virus type 1 infection: safety and host response. J. Infect. Dis. 178(1), 92-100 (1998).
    • (1998) J. Infect. Dis. , vol.178 , Issue.1 , pp. 92-100
    • MacGregor, R.R.1    Boyer, J.D.2    Ugen, K.E.3
  • 145
    • 37349109250 scopus 로고    scopus 로고
    • Plasmid DNA-and messenger RNA-based anti-cancer vaccination
    • Weide B, Garbe C, Rammensee H-G, Pascolo S. Plasmid DNA-and messenger RNA-based anti-cancer vaccination. Immunol. Lett. 115(1), 33-42 (2008).
    • (2008) Immunol. Lett. , vol.115 , Issue.1 , pp. 33-42
    • Weide, B.1    Garbe, C.2    Rammensee, H.-G.3    Pascolo, S.4


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