Formation of drug-arylsulfonate complexes inside liposomes: A novel approach to improve drug retention

Journal of Controlled Release

Volumn 110, Issue 2, 2006, Pages 378-386

  Zhigaltsev, Igor V ^a   Maurer, Norbert ^b   Edwards, Katarina ^c   Karlsson, Göran ^c   Cullis, Pieter R ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Inex Pharmaceuticals Corporation   (Canada)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Arylsulfonates; Ciprofloxacin; Drug release; Liposome; Vinorelbine

Indexed keywords

COMPLEXATION; ESTERS; PRECIPITATION (CHEMICAL); PROTEINS;

ARYLSULFONATES; CIPROFLOXACIN; DRUG RELEASE; LIPOSOME; VINORELBINE;

DRUG DOSAGE;

4 HYDROXYBENZESULFONATE; ARYLSULFONIC ACID DERIVATIVE; BENZENESULFONIC ACID DERIVATIVE; CALCIUM SALT; CIPROFLOXACIN; IONOPHORE; LIPOSOME; MAGNESIUM SULFATE; NAVELBINE; UNCLASSIFIED DRUG; VINORELBINE DITARTRATE;

ARTICLE; COMPARATIVE STUDY; CRYOELECTRON MICROSCOPY; DRUG HALF LIFE; DRUG RELEASE; DRUG RETENTION; ENCAPSULATION; LIPOPHILICITY; MOUSE; NONHUMAN; PH MEASUREMENT; PRECIPITATION; PRIORITY JOURNAL; SOLUTE; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ARYLSULFONATES; CHEMISTRY, PHARMACEUTICAL; CIPROFLOXACIN; CRYOELECTRON MICROSCOPY; EXCIPIENTS; FEMALE; HT29 CELLS; HUMANS; LIPOSOMES; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NEOPLASM TRANSPLANTATION; SOLUTIONS; VINBLASTINE;

EID: 29244439986     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.10.011     Document Type: Article

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