Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models

Free Radical Biology and Medicine

Volumn 52, Issue 8, 2012, Pages 1362-1371

  Zampagni, Mariagioia ^a   Wright, Daniel ^a   Cascella, Roberta ^a   D'Adamio, Giampiero ^a   Casamenti, Fiorella ^a   Evangelisti, Elisa ^a   Cardona, Francesca ^a   Goti, Andrea ^a   Nacmias, Benedetta ^a   Sorbi, Sandro ^a   Liguri, Gianfranco ^a   Cecchi, Cristina ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

A 42 toxicity; Antioxidants; Cholinergic neurons; Familial Alzheimer fibroblasts; Free radicals; Oxidative stress; Polyunsaturated fatty acids; S acyl glutathione derivatives; Thioester chemical synthesis

Indexed keywords

ACYL BENZOTRIAZOLE; ACYL GLUTATHIONE DERIVATIVE; AMYLOID BETA PROTEIN[1-42]; BENZOTRIAZOLE DERIVATIVE; FATTY ACID; GLUTATHIONE DERIVATIVE; THIOESTER; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CANCER CELL CULTURE; DRUG MECHANISM; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NEUROBLASTOMA; OXIDATIVE STRESS; PRIORITY JOURNAL;

AMYLOID; ANIMALS; BRAIN; CASPASE 3; CELL LINE, TUMOR; CELLS, CULTURED; ENZYME ACTIVATION; FLUORESCENT ANTIBODY TECHNIQUE; GLUTATHIONE; HUMANS; MODELS, BIOLOGICAL; OXIDATIVE STRESS; RATS; RECEPTORS, CHOLINERGIC;

RATTUS;

EID: 84859009663     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.01.012     Document Type: Article

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