Rutin inhibits β-amyloid aggregation and cytotoxicity, attenuates oxidative stress, and decreases the production of nitric oxide and proinflammatory cytokines

NeuroToxicology

Volumn 33, Issue 3, 2012, Pages 482-490

  Wang, Shao Wei ^a,b   Wang, Yu Jiong ^b   Su, Ya Jing ^a   Zhou, Wei Wei ^a,c   Yang, Shi Gao ^a   Zhang, Ran ^a   Zhao, Min ^a   Li, Ya Nan ^a   Zhang, Zi Ping ^b   Zhan, Da Wei ^c   Liu, Rui Tian ^a  

^a Tsinghua University   (China)

^b NINGXIA UNIVERSITY   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Amyloid; Aggregation; Alzheimer's disease; Nitric oxide; Proinflammatory cytokines; Reactive oxygen species; Rutin

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; CATALASE; CYTOKINE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MALONALDEHYDE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; RUTOSIDE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOMODULATION; MICROGLIA; MITOCHONDRION; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN SYNTHESIS INHIBITION;

AMYLOID BETA-PEPTIDES; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CATALASE; CELL LINE, TUMOR; CYTOKINES; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MALONDIALDEHYDE; MITOCHONDRIA; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; REACTIVE OXYGEN SPECIES; RUTIN; SUPEROXIDE DISMUTASE; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84861202049     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.03.003     Document Type: Article

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