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Volumn 38, Issue , 2013, Pages 106-114

Anti-oxidative and anti-inflammatory effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride on glutamate-induced neurotoxicity in rat brain

Author keywords

2 Cyclopropylimino 3 methyl 1,3 thiazoline hydrochloride; Calcium; Cytokines; Glutamate; Reactive oxygen species

Indexed keywords

2 CYCLOPROPYLIMINO 3 METHYL 1,3 THIAZOLINE; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CALCIUM ION; CASPASE 3; CATALASE; GAMMA INTERFERON; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; KHG 26377; MITOGEN ACTIVATED PROTEIN KINASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84881303781     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2013.07.001     Document Type: Article
Times cited : (22)

References (78)
  • 1
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol 1984, 105:121-126.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 2
    • 0037113280 scopus 로고    scopus 로고
    • Presence of mitogen-activated protein kinase in retinal Muller cells and its neuroprotective effect ischemia - reperfusion injury
    • Akiyama H., Nakazawa T., Shimura M., Tomita H., Tamai M. Presence of mitogen-activated protein kinase in retinal Muller cells and its neuroprotective effect ischemia - reperfusion injury. NeuroReport 2002, 13:2103-2107.
    • (2002) NeuroReport , vol.13 , pp. 2103-2107
    • Akiyama, H.1    Nakazawa, T.2    Shimura, M.3    Tomita, H.4    Tamai, M.5
  • 3
    • 33947238794 scopus 로고    scopus 로고
    • Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury
    • Bayir H., Kagan V.E., Clark R.S., Janesko-Feldman K., Rafikov R., Huang Z., et al. Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury. J Neurochem 2007, 101:168-181.
    • (2007) J Neurochem , vol.101 , pp. 168-181
    • Bayir, H.1    Kagan, V.E.2    Clark, R.S.3    Janesko-Feldman, K.4    Rafikov, R.5    Huang, Z.6
  • 4
    • 0029125857 scopus 로고
    • Aging, energy, and oxidative stress in neurodegenerative diseases
    • Beal M.F. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 1995, 38:357-366.
    • (1995) Ann Neurol , vol.38 , pp. 357-366
    • Beal, M.F.1
  • 5
    • 0032032424 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-α gene expression in endotoxin-stimulated primary glial cultures
    • Bhat N.R., Zhang P., Lee J.C., Hogan E.L. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-α gene expression in endotoxin-stimulated primary glial cultures. J Neurosci 1998, 18:1633-1641.
    • (1998) J Neurosci , vol.18 , pp. 1633-1641
    • Bhat, N.R.1    Zhang, P.2    Lee, J.C.3    Hogan, E.L.4
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 34250751339 scopus 로고    scopus 로고
    • Nitric oxide and superoxide: interference with hypoxic signaling
    • Brune B., Zhou J. Nitric oxide and superoxide: interference with hypoxic signaling. Cardiovasc Res 2007, 75:275-282.
    • (2007) Cardiovasc Res , vol.75 , pp. 275-282
    • Brune, B.1    Zhou, J.2
  • 8
    • 0034765766 scopus 로고    scopus 로고
    • Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils
    • Candelario-Jalil E., Mhadu N.H., Al-Dalain S.M., Martínez G., León O.S. Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils. Neurosci Res 2001, 41:233-241.
    • (2001) Neurosci Res , vol.41 , pp. 233-241
    • Candelario-Jalil, E.1    Mhadu, N.H.2    Al-Dalain, S.M.3    Martínez, G.4    León, O.S.5
  • 10
    • 22144488038 scopus 로고    scopus 로고
    • Proinflammatory cytokines and apoptosis following glutamate-induced excitotoxicity mediated by p38 MAPK in the hippocampus of neonatal rats
    • Chaparro-Huerta V., Rivera-Cervantes M.C., Flores-Soto M.E., Gomez-Pinedo U., Beas-Zarate C. Proinflammatory cytokines and apoptosis following glutamate-induced excitotoxicity mediated by p38 MAPK in the hippocampus of neonatal rats. J Neuroimmunol 2005, 165:53-62.
    • (2005) J Neuroimmunol , vol.165 , pp. 53-62
    • Chaparro-Huerta, V.1    Rivera-Cervantes, M.C.2    Flores-Soto, M.E.3    Gomez-Pinedo, U.4    Beas-Zarate, C.5
  • 12
    • 79960082531 scopus 로고    scopus 로고
    • Antioxidant activity of 7,8-dihydroxyflavone provides neuroprotection against glutamate-induced toxicity
    • Chen J., Chua K.W., Chua C.C., Yu H., Pei A., Chua B.H., et al. Antioxidant activity of 7,8-dihydroxyflavone provides neuroprotection against glutamate-induced toxicity. Neurosci Lett 2011, 499:181-185.
    • (2011) Neurosci Lett , vol.499 , pp. 181-185
    • Chen, J.1    Chua, K.W.2    Chua, C.C.3    Yu, H.4    Pei, A.5    Chua, B.H.6
  • 13
    • 34447550144 scopus 로고    scopus 로고
    • PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK
    • Chen R.W., Lu X.C., Yao C., Liao Z., Jiang Z.G., Wei H., et al. PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK. Neurosci Lett 2007, 422:64-67.
    • (2007) Neurosci Lett , vol.422 , pp. 64-67
    • Chen, R.W.1    Lu, X.C.2    Yao, C.3    Liao, Z.4    Jiang, Z.G.5    Wei, H.6
  • 14
    • 34548299422 scopus 로고    scopus 로고
    • Protective effect of benzothiazole derivative KHG21834 on amyloid beta-induced neurotoxicity in PC12 cells and cortical and mesencephalic neurons
    • Choi M.-M., Kim E.-A., Hahn H.G., Nam K.D., Yang S.-J., Choi S.Y., et al. Protective effect of benzothiazole derivative KHG21834 on amyloid beta-induced neurotoxicity in PC12 cells and cortical and mesencephalic neurons. Toxicology 2007, 239:156-166.
    • (2007) Toxicology , vol.239 , pp. 156-166
    • Choi, M.-M.1    Kim, E.-A.2    Hahn, H.G.3    Nam, K.D.4    Yang, S.-J.5    Choi, S.Y.6
  • 15
    • 84859031263 scopus 로고    scopus 로고
    • The oxidative stress-inducible cystine/glutamate antiporter, system x (c) (-):cystine supplier and beyond
    • Conrad M., Sato H. The oxidative stress-inducible cystine/glutamate antiporter, system x (c) (-):cystine supplier and beyond. Amino Acids 2012, 42:231-246.
    • (2012) Amino Acids , vol.42 , pp. 231-246
    • Conrad, M.1    Sato, H.2
  • 16
    • 0027178135 scopus 로고
    • Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures
    • Dawson V.L., Dawson T.M., Bartley D.A., Uhl G.R., Snyder S.H. Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J Neurosci 1993, 13:2651-2661.
    • (1993) J Neurosci , vol.13 , pp. 2651-2661
    • Dawson, V.L.1    Dawson, T.M.2    Bartley, D.A.3    Uhl, G.R.4    Snyder, S.H.5
  • 17
    • 0034668833 scopus 로고    scopus 로고
    • Mitochondria and calcium: from cell signaling to cell death
    • Duchen M. Mitochondria and calcium: from cell signaling to cell death. J Physiol 2000, 529:57-68.
    • (2000) J Physiol , vol.529 , pp. 57-68
    • Duchen, M.1
  • 18
    • 0021288821 scopus 로고
    • Assay of glutathione peroxidase
    • Flohe L., Ginzler W.A. Assay of glutathione peroxidase. Methods Enzymol 1984, 105:114-121.
    • (1984) Methods Enzymol , vol.105 , pp. 114-121
    • Flohe, L.1    Ginzler, W.A.2
  • 19
    • 37349063346 scopus 로고    scopus 로고
    • Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1
    • Fumagalli E., Funicello M., Rauen T., Gobbi M., Mennini T. Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1. Eur J Pharmacol 2008, 578:171-176.
    • (2008) Eur J Pharmacol , vol.578 , pp. 171-176
    • Fumagalli, E.1    Funicello, M.2    Rauen, T.3    Gobbi, M.4    Mennini, T.5
  • 20
    • 0021895138 scopus 로고
    • A new generation of calcium indicators with greatly improved fluorescence properties
    • Grynkiewicz G., Poenie M., Tsien R.Y. A new generation of calcium indicators with greatly improved fluorescence properties. J Biol Chem 1985, 260:3440-3450.
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 21
    • 23444445727 scopus 로고    scopus 로고
    • Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway
    • Guo S., Bezard E., Zhao B. Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway. Free Radic Biol Med 2005, 39:682-695.
    • (2005) Free Radic Biol Med , vol.39 , pp. 682-695
    • Guo, S.1    Bezard, E.2    Zhao, B.3
  • 22
    • 33745013111 scopus 로고    scopus 로고
    • Oxidative stress and neurodegeneration: where are we now?
    • Halliwell B. Oxidative stress and neurodegeneration: where are we now?. J Neurochem 2006, 97:1634-1658.
    • (2006) J Neurochem , vol.97 , pp. 1634-1658
    • Halliwell, B.1
  • 23
    • 0036849077 scopus 로고    scopus 로고
    • The biochemistry and medical significance of the flavonoids
    • Havsteen B.H. The biochemistry and medical significance of the flavonoids. Pharmacol Ther 2002, 96:67-202.
    • (2002) Pharmacol Ther , vol.96 , pp. 67-202
    • Havsteen, B.H.1
  • 25
    • 80054810404 scopus 로고    scopus 로고
    • Chloroquine inhibits glutamate-induced death of a neuronal cell line by reducing reactive oxygen species through sigma-1 receptor
    • Hirata Y., Yamamoto H., Atta M.S., Mahmoud S., Oh-hashi K., Kiuchi K. Chloroquine inhibits glutamate-induced death of a neuronal cell line by reducing reactive oxygen species through sigma-1 receptor. J Neurochem 2011, 119:839-847.
    • (2011) J Neurochem , vol.119 , pp. 839-847
    • Hirata, Y.1    Yamamoto, H.2    Atta, M.S.3    Mahmoud, S.4    Oh-hashi, K.5    Kiuchi, K.6
  • 26
    • 84862782733 scopus 로고    scopus 로고
    • Aberrant regulation and function of Src family tyrosine kinases: their potential contributions to glutamate-induced neurotoxicity
    • Hossain M.I., Kamaruddin M.A., Cheng H.C. Aberrant regulation and function of Src family tyrosine kinases: their potential contributions to glutamate-induced neurotoxicity. Clin Exp Pharmacol Physiol 2012, 39:684-691.
    • (2012) Clin Exp Pharmacol Physiol , vol.39 , pp. 684-691
    • Hossain, M.I.1    Kamaruddin, M.A.2    Cheng, H.C.3
  • 27
    • 33747378086 scopus 로고    scopus 로고
    • Oxidation-induced changes in human lens epithelial cells 2. Mitochondria and the generation of reactive oxygen species
    • Huang L., Tang D., Yappert M.C., Borchman D. Oxidation-induced changes in human lens epithelial cells 2. Mitochondria and the generation of reactive oxygen species. Free Radic Biol Med 2006, 41:926-936.
    • (2006) Free Radic Biol Med , vol.41 , pp. 926-936
    • Huang, L.1    Tang, D.2    Yappert, M.C.3    Borchman, D.4
  • 28
    • 8744278883 scopus 로고    scopus 로고
    • Glutamate as a therapeutic target in psychiatric disorders
    • Javitt D.C. Glutamate as a therapeutic target in psychiatric disorders. Mol Psychiatr 2004, 9:984-997.
    • (2004) Mol Psychiatr , vol.9 , pp. 984-997
    • Javitt, D.C.1
  • 29
    • 46849097142 scopus 로고    scopus 로고
    • NMDA receptors in clinical neurology: excitatory times ahead
    • Kalia L.V., Kalia S.K., Salter M.W. NMDA receptors in clinical neurology: excitatory times ahead. Lancet Neurol 2008, 7:742-755.
    • (2008) Lancet Neurol , vol.7 , pp. 742-755
    • Kalia, L.V.1    Kalia, S.K.2    Salter, M.W.3
  • 30
    • 3042658601 scopus 로고    scopus 로고
    • Effects of mitochondrial dysfunction on glutamate receptor-mediated neurotoxicity in cultured rat spinal motor neurons
    • Kanki R., Nakamizo T., Yamashita H., Kihara T., Sawada H., Uemura K., et al. Effects of mitochondrial dysfunction on glutamate receptor-mediated neurotoxicity in cultured rat spinal motor neurons. Brain Res 2004, 1015:73-81.
    • (2004) Brain Res , vol.1015 , pp. 73-81
    • Kanki, R.1    Nakamizo, T.2    Yamashita, H.3    Kihara, T.4    Sawada, H.5    Uemura, K.6
  • 31
    • 70350558453 scopus 로고    scopus 로고
    • Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
    • Kigerl K.A., Gensel J.C., Ankeny D.P., Alexander J.K., Donnelly D.J., Popovich P.G. Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J Neurosci 2009, 29:13435-13444.
    • (2009) J Neurosci , vol.29 , pp. 13435-13444
    • Kigerl, K.A.1    Gensel, J.C.2    Ankeny, D.P.3    Alexander, J.K.4    Donnelly, D.J.5    Popovich, P.G.6
  • 32
    • 77956264216 scopus 로고    scopus 로고
    • Suppression of glutamate-induced excitotoxicity by 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride in rat glial cultures
    • Kim E-A., Hahn H-G., Kim K-S., Kim T.U., Choi S.Y., Cho S-W. Suppression of glutamate-induced excitotoxicity by 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride in rat glial cultures. Cell Mol Neurobiol 2010, 30:807-815.
    • (2010) Cell Mol Neurobiol , vol.30 , pp. 807-815
    • Kim, E.-A.1    Hahn, H.-G.2    Kim, K.-S.3    Kim, T.U.4    Choi, S.Y.5    Cho, S.-W.6
  • 33
    • 77955836320 scopus 로고    scopus 로고
    • Attenuation of β-amyloid-induced neuroinflammation by KHG21834 in vivo
    • Kim E-A., Hahn H-G., Kim T.U., Choi S.Y., Cho S-W. Attenuation of β-amyloid-induced neuroinflammation by KHG21834 in vivo. BMB Rep 2010, 43:413-418.
    • (2010) BMB Rep , vol.43 , pp. 413-418
    • Kim, E.-A.1    Hahn, H.-G.2    Kim, T.U.3    Choi, S.Y.4    Cho, S.-W.5
  • 34
    • 85027949963 scopus 로고    scopus 로고
    • Neuroprotective effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride against oxidative stress
    • Kim H., Son H.J., Ha S.C., Kim E.A., Kim T.U., Choi S.Y., et al. Neuroprotective effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride against oxidative stress. Cell Mol Neurobiol 2011, 31:979-984.
    • (2011) Cell Mol Neurobiol , vol.31 , pp. 979-984
    • Kim, H.1    Son, H.J.2    Ha, S.C.3    Kim, E.A.4    Kim, T.U.5    Choi, S.Y.6
  • 35
    • 78649732832 scopus 로고    scopus 로고
    • Bax regulates production of superoxide in both apoptotic and nonapoptotic neurons: role of caspases
    • Kirkland R.A., Saavedra G.M., Cummings B.S., Franklin J.L. Bax regulates production of superoxide in both apoptotic and nonapoptotic neurons: role of caspases. J Neurosci 2010, 30:16114-16127.
    • (2010) J Neurosci , vol.30 , pp. 16114-16127
    • Kirkland, R.A.1    Saavedra, G.M.2    Cummings, B.S.3    Franklin, J.L.4
  • 37
    • 66749109859 scopus 로고    scopus 로고
    • Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonists
    • Kulkarni S.S., Zou M.F., Cao J., Deschamps J.R., Rodriguez A.L., Conn P.J., et al. Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonists. J Med Chem 2009, 52:3563-3575.
    • (2009) J Med Chem , vol.52 , pp. 3563-3575
    • Kulkarni, S.S.1    Zou, M.F.2    Cao, J.3    Deschamps, J.R.4    Rodriguez, A.L.5    Conn, P.J.6
  • 38
    • 77049101945 scopus 로고    scopus 로고
    • Cell death mechanisms in the early stages of acute glutamate neurotoxicity
    • Kumar A., Singh R.L., Babu G.N. Cell death mechanisms in the early stages of acute glutamate neurotoxicity. Neurosci Res 2010, 66:271-278.
    • (2010) Neurosci Res , vol.66 , pp. 271-278
    • Kumar, A.1    Singh, R.L.2    Babu, G.N.3
  • 39
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • Lafon-Cazal M., Pietri S., Culcasi M., Bockaert J. NMDA-dependent superoxide production and neurotoxicity. Nature 1993, 364:535-537.
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 40
    • 65649105776 scopus 로고    scopus 로고
    • Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism
    • Lebrun-Julien F., Duplan L., Pernet V., Osswald I., Sapieha P., Bourgeois P., et al. Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism. J Neurosci 2009, 29:5536-5545.
    • (2009) J Neurosci , vol.29 , pp. 5536-5545
    • Lebrun-Julien, F.1    Duplan, L.2    Pernet, V.3    Osswald, I.4    Sapieha, P.5    Bourgeois, P.6
  • 41
    • 48249144783 scopus 로고    scopus 로고
    • Concomitant degradation of β-catenin and GSK-3β potently contributes to glutamate-induced neurotoxicity in rat hippocampal slice cultures
    • Lee J.H., Lee E.O., Kang J.L., Chong Y.H. Concomitant degradation of β-catenin and GSK-3β potently contributes to glutamate-induced neurotoxicity in rat hippocampal slice cultures. J Neurochem 2008, 106:1066-1077.
    • (2008) J Neurochem , vol.106 , pp. 1066-1077
    • Lee, J.H.1    Lee, E.O.2    Kang, J.L.3    Chong, Y.H.4
  • 42
    • 0036088542 scopus 로고    scopus 로고
    • Production of superoxide through NADH oxidase in thick ascending limb of Henle's loop in rat kidney
    • Li N., Yi F.X., Spurrier J.L., Bobrowitz C.A., Zou A.P. Production of superoxide through NADH oxidase in thick ascending limb of Henle's loop in rat kidney. Am J Physiol Renal Physiol 2002, 282:F1111-F1119.
    • (2002) Am J Physiol Renal Physiol , vol.282
    • Li, N.1    Yi, F.X.2    Spurrier, J.L.3    Bobrowitz, C.A.4    Zou, A.P.5
  • 43
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton S.A. Ischemic cell death in brain neurons. Physiol Rev 1999, 79:1431-1568.
    • (1999) Physiol Rev , vol.79 , pp. 1431-1568
    • Lipton, S.A.1
  • 44
    • 0033532275 scopus 로고    scopus 로고
    • Astrocytic demise precedes delayed neuronal death in focal ischemic rat brain
    • Liu D., Smith C.L., Barone F.C., Ellison J.A., Lysko P.G., Li K., et al. Astrocytic demise precedes delayed neuronal death in focal ischemic rat brain. Mol Brain Res 1999, 68:29-41.
    • (1999) Mol Brain Res , vol.68 , pp. 29-41
    • Liu, D.1    Smith, C.L.2    Barone, F.C.3    Ellison, J.A.4    Lysko, P.G.5    Li, K.6
  • 45
    • 71249098179 scopus 로고    scopus 로고
    • Tissue kallikrein alleviates glutamate-induced neurotoxicity by activating ERK1
    • Liu L., Zhang R., Liu K., Zhou H., Tang Y., Su J., et al. Tissue kallikrein alleviates glutamate-induced neurotoxicity by activating ERK1. J Neurosci Res 2009, 87:3576-3590.
    • (2009) J Neurosci Res , vol.87 , pp. 3576-3590
    • Liu, L.1    Zhang, R.2    Liu, K.3    Zhou, H.4    Tang, Y.5    Su, J.6
  • 48
    • 22544462551 scopus 로고    scopus 로고
    • Antioxidant strategies in the treatment of stroke
    • Margaill I., Plotkine M., Lerouet D. Antioxidant strategies in the treatment of stroke. Free Radic Biol Med 2005, 39:429-443.
    • (2005) Free Radic Biol Med , vol.39 , pp. 429-443
    • Margaill, I.1    Plotkine, M.2    Lerouet, D.3
  • 49
    • 79957460640 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors
    • McElnea E.M., Quill B., Docherty N.G., Irnaten M., Siah W.F., Clark A.F., et al. Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors. Mol Vis 2011, 17:1182-1191.
    • (2011) Mol Vis , vol.17 , pp. 1182-1191
    • McElnea, E.M.1    Quill, B.2    Docherty, N.G.3    Irnaten, M.4    Siah, W.F.5    Clark, A.F.6
  • 50
    • 44949240517 scopus 로고    scopus 로고
    • Interferon gamma directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-gamma receptor and AMPAGluR1 receptor
    • Mizuno T., Zhang G., Takeuchi H., Kawanokuchi J., Wang J., Sonobe Y., et al. Interferon gamma directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-gamma receptor and AMPAGluR1 receptor. FASEB J 2008, 22:1797-1806.
    • (2008) FASEB J , vol.22 , pp. 1797-1806
    • Mizuno, T.1    Zhang, G.2    Takeuchi, H.3    Kawanokuchi, J.4    Wang, J.5    Sonobe, Y.6
  • 51
    • 0029832301 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury
    • Mukhin A., Fan L., Faden A.L. Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury. J Neurosci 1996, 16:6012-6020.
    • (1996) J Neurosci , vol.16 , pp. 6012-6020
    • Mukhin, A.1    Fan, L.2    Faden, A.L.3
  • 52
    • 79951857865 scopus 로고    scopus 로고
    • NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion
    • Murotomi K., Takagi N., Takeo S., Tanonaka K. NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion. Mol Cell Neurosci 2011, 46:681-688.
    • (2011) Mol Cell Neurosci , vol.46 , pp. 681-688
    • Murotomi, K.1    Takagi, N.2    Takeo, S.3    Tanonaka, K.4
  • 53
    • 24644462789 scopus 로고    scopus 로고
    • Mitochondria and calcium signaling
    • Nicholls D.G. Mitochondria and calcium signaling. Cell Calcium 2005, 38:311-317.
    • (2005) Cell Calcium , vol.38 , pp. 311-317
    • Nicholls, D.G.1
  • 54
    • 0037304154 scopus 로고    scopus 로고
    • Excitotoxicity, apoptosis and neuropsychiatric disorders
    • Olney J.W. Excitotoxicity, apoptosis and neuropsychiatric disorders. Curr Opin Pharmacol 2003, 3:101-109.
    • (2003) Curr Opin Pharmacol , vol.3 , pp. 101-109
    • Olney, J.W.1
  • 55
    • 77956920674 scopus 로고    scopus 로고
    • Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy
    • Pestana R.R., Kinjo E.R., Hernandes M.S., Britto L.R. Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy. Neurosci Lett 2010, 484:187-191.
    • (2010) Neurosci Lett , vol.484 , pp. 187-191
    • Pestana, R.R.1    Kinjo, E.R.2    Hernandes, M.S.3    Britto, L.R.4
  • 57
    • 0030060186 scopus 로고    scopus 로고
    • Mitochondrial generation of reactive oxygen species after brain ischemia in the rat
    • Piantadosi C.A., Zhang J. Mitochondrial generation of reactive oxygen species after brain ischemia in the rat. Stroke 1996, 27:327-331.
    • (1996) Stroke , vol.27 , pp. 327-331
    • Piantadosi, C.A.1    Zhang, J.2
  • 58
    • 0346728670 scopus 로고    scopus 로고
    • Neurotoxicity, oxidative stress and cerebrovascular disorders
    • Qureshi G.A., Baig S., Sarwar M., Parvez S.H. Neurotoxicity, oxidative stress and cerebrovascular disorders. Neurotoxicology 2004, 25:121-138.
    • (2004) Neurotoxicology , vol.25 , pp. 121-138
    • Qureshi, G.A.1    Baig, S.2    Sarwar, M.3    Parvez, S.H.4
  • 59
    • 0000274424 scopus 로고
    • Glutathione reductase from bakers' yeast and beef liver
    • Racker E. Glutathione reductase from bakers' yeast and beef liver. J Biol Chem 1955, 217:855-865.
    • (1955) J Biol Chem , vol.217 , pp. 855-865
    • Racker, E.1
  • 60
    • 0029064518 scopus 로고
    • Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
    • Reynolds I.J., Hastings T.G. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J Neurosci 1995, 15:3318-3327.
    • (1995) J Neurosci , vol.15 , pp. 3318-3327
    • Reynolds, I.J.1    Hastings, T.G.2
  • 61
    • 68949136974 scopus 로고    scopus 로고
    • Discovery and in vitro and in vivo profiles of 4-fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist
    • Satoh A., Nagatomi Y., Hirata Y., Ito S., Suzuki G., Kimura T., et al. Discovery and in vitro and in vivo profiles of 4-fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist. Bioorg Med Chem Lett 2009, 19:5464-5468.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 5464-5468
    • Satoh, A.1    Nagatomi, Y.2    Hirata, Y.3    Ito, S.4    Suzuki, G.5    Kimura, T.6
  • 62
    • 36448981390 scopus 로고    scopus 로고
    • Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology
    • Schreibelt G., van Horssen J., van Rossum S., Dijkstra C.D., Drukarch B., de Vries H.E. Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology. Brain Res Rev 2007, 56:322-330.
    • (2007) Brain Res Rev , vol.56 , pp. 322-330
    • Schreibelt, G.1    van Horssen, J.2    van Rossum, S.3    Dijkstra, C.D.4    Drukarch, B.5    de Vries, H.E.6
  • 64
    • 34249016295 scopus 로고    scopus 로고
    • Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats
    • Sharma S.S., Kaundal R.K. Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Neurol Res 2007, 29:304-309.
    • (2007) Neurol Res , vol.29 , pp. 304-309
    • Sharma, S.S.1    Kaundal, R.K.2
  • 65
    • 0033963231 scopus 로고    scopus 로고
    • Autoimmune encephalomyelitis ameliorated by AMPA antagonists
    • Smith T., Groom A., Zhu B., Turski L. Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nat Med 2000, 6:62-66.
    • (2000) Nat Med , vol.6 , pp. 62-66
    • Smith, T.1    Groom, A.2    Zhu, B.3    Turski, L.4
  • 66
    • 0034697364 scopus 로고    scopus 로고
    • Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures
    • Stanciu M., Wang Y., Kentor R., Burke N., Watkins S., Kress G., et al. Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. J Biol Chem 2000, 275:12200-12206.
    • (2000) J Biol Chem , vol.275 , pp. 12200-12206
    • Stanciu, M.1    Wang, Y.2    Kentor, R.3    Burke, N.4    Watkins, S.5    Kress, G.6
  • 67
    • 34147117776 scopus 로고    scopus 로고
    • Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase
    • Suh S.W., Gum E.T., Hamby A.M., Chan P.H., Swanson R.A. Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase. J Clin Invest 2007, 117:910-918.
    • (2007) J Clin Invest , vol.117 , pp. 910-918
    • Suh, S.W.1    Gum, E.T.2    Hamby, A.M.3    Chan, P.H.4    Swanson, R.A.5
  • 68
    • 58149268010 scopus 로고    scopus 로고
    • Glucose and NADPH oxidase drive neuronal superoxide formation in stroke
    • Suh S.W., Shin B.S., Ma H., Van Hoecke M., Brennan A.M., Yenari M.A., et al. Glucose and NADPH oxidase drive neuronal superoxide formation in stroke. Ann Neurol 2008, 64:654-663.
    • (2008) Ann Neurol , vol.64 , pp. 654-663
    • Suh, S.W.1    Shin, B.S.2    Ma, H.3    Van Hoecke, M.4    Brennan, A.M.5    Yenari, M.A.6
  • 71
    • 0034176591 scopus 로고    scopus 로고
    • A new concept in neurodegeneration: TNFalpha is a silencer of survival signals
    • Venters H.D., Dantzer R., Kelley K.W. A new concept in neurodegeneration: TNFalpha is a silencer of survival signals. Trends Neurosci 2000, 23:175-180.
    • (2000) Trends Neurosci , vol.23 , pp. 175-180
    • Venters, H.D.1    Dantzer, R.2    Kelley, K.W.3
  • 72
    • 33846245536 scopus 로고    scopus 로고
    • Regulation of mitogen-activated protein kinases by glutamate receptors
    • Wang J.Q., Fibuch E.E., Mao L. Regulation of mitogen-activated protein kinases by glutamate receptors. J Neurochem 2007, 100:1-11.
    • (2007) J Neurochem , vol.100 , pp. 1-11
    • Wang, J.Q.1    Fibuch, E.E.2    Mao, L.3
  • 73
    • 27744561802 scopus 로고    scopus 로고
    • Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits
    • Wang Q., Sun A.Y., Simonyi A., Jensen M.D., Shelat P.B., Rottinghaus G.E., et al. Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits. J Neurosci Res 2005, 82:138-148.
    • (2005) J Neurosci Res , vol.82 , pp. 138-148
    • Wang, Q.1    Sun, A.Y.2    Simonyi, A.3    Jensen, M.D.4    Shelat, P.B.5    Rottinghaus, G.E.6
  • 74
    • 79958723738 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of spinocerebellar ataxia type 12 (SCA12)
    • Wang Y.C., Lee C.M., Lee L.C., Tung L.C., Hsieh-Li H.M., Lee-Chen G.J., et al. Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of spinocerebellar ataxia type 12 (SCA12). J Biol Chem 2011, 286:21742-21754.
    • (2011) J Biol Chem , vol.286 , pp. 21742-21754
    • Wang, Y.C.1    Lee, C.M.2    Lee, L.C.3    Tung, L.C.4    Hsieh-Li, H.M.5    Lee-Chen, G.J.6
  • 75
    • 0030615095 scopus 로고    scopus 로고
    • 2+ dependent NO-production form central nervous system cells in culture measured by NO-nitrite/ozone chemoluminescence
    • 2+ dependent NO-production form central nervous system cells in culture measured by NO-nitrite/ozone chemoluminescence. Brain Res 1997, 748:1-11.
    • (1997) Brain Res , vol.748 , pp. 1-11
    • Weikert, S.1    Freyer, D.2    Weh, M.3    Isaev, N.4    Busch, C.5    Schultze, J.6
  • 76
    • 84879696556 scopus 로고    scopus 로고
    • Pyrroloquinoline quinine protects rat brain cortex against acute glutamate-induced neurotoxicity
    • Zhang Q., Ding M., Cao Z., Zhang J., Ding F., Ke K. Pyrroloquinoline quinine protects rat brain cortex against acute glutamate-induced neurotoxicity. Neurochem Res 2013, 38:1661-1671.
    • (2013) Neurochem Res , vol.38 , pp. 1661-1671
    • Zhang, Q.1    Ding, M.2    Cao, Z.3    Zhang, J.4    Ding, F.5    Ke, K.6
  • 77
    • 79952624790 scopus 로고    scopus 로고
    • The neuroprotective action of pyrroloquinolinequinone against glutamate-induced apoptosis in hippocampal neurons is mediated through the activation of PI3K/Akt pathway
    • Zhang Q., Shen M., Ding M., Shen D., Ding F. The neuroprotective action of pyrroloquinolinequinone against glutamate-induced apoptosis in hippocampal neurons is mediated through the activation of PI3K/Akt pathway. Toxicol Appl Pharmacol 2011, 252:62-72.
    • (2011) Toxicol Appl Pharmacol , vol.252 , pp. 62-72
    • Zhang, Q.1    Shen, M.2    Ding, M.3    Shen, D.4    Ding, F.5
  • 78
    • 33947322693 scopus 로고    scopus 로고
    • Role of extracellular signal-regulated kinase in glutamate-stimulated apoptosis of rat retinal ganglion cells
    • Zhou R.H., Yan H., Wang B.R., Kuang F., Duan X.L., Xu Z. Role of extracellular signal-regulated kinase in glutamate-stimulated apoptosis of rat retinal ganglion cells. Curr Eye Res 2007, 32:233-239.
    • (2007) Curr Eye Res , vol.32 , pp. 233-239
    • Zhou, R.H.1    Yan, H.2    Wang, B.R.3    Kuang, F.4    Duan, X.L.5    Xu, Z.6


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