Liberation of copper from amyloid plaques: Making a risk factor useful for alzheimers disease treatment

Journal of Medicinal Chemistry

Volumn 55, Issue 21, 2012, Pages 9146-9155

  Geng, Jie ^a,b   Li, Meng ^a,b   Wu, Li ^a,b   Ren, Jinsong ^a   Qu, Xiaogang ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 [(BENZO[D]THIAZOL 2 YLIMINO)METHYL] 4 CHLOROPHENOL; 2 [(BENZO[D]THIAZOL 2 YLIMINO)METHYL] 4 NITROPHENOL; 2 [(BENZO[D]THIAZOL 2 YLIMINO)METHYL]PHENOL; AMYLOID BETA PROTEIN[1-40]; CHELATING AGENT; COPPER ION; SCHIFF BASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG MECHANISM; DRUG SYNTHESIS; NONHUMAN; RAT; REACTION ANALYSIS;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BENZOTHIAZOLES; BLOOD-BRAIN BARRIER; CELL SURVIVAL; CHELATING AGENTS; CHLOROPHENOLS; COORDINATION COMPLEXES; COPPER; DIMERIZATION; NITROPHENOLS; PC12 CELLS; PHENOLS; PLAQUE, AMYLOID; RATS; REACTIVE OXYGEN SPECIES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDE DISMUTASE;

EID: 84868542498     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3003813     Document Type: Article

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