메뉴 건너뛰기




Volumn 36, Issue 4, 2016, Pages 226-237

STAT5 in Cancer and Immunity

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; GROWTH FACTOR; INTERLEUKIN 2; JANUS KINASE; STAT5 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN; CYTOKINE;

EID: 84964220748     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.2015.0054     Document Type: Article
Times cited : (141)

References (164)
  • 1
    • 0037204953 scopus 로고    scopus 로고
    • A road map for those who don't know JAK-STAT
    • Aaronson DS, Horvath CM. 2002. A road map for those who don't know JAK-STAT. Science 296(5573):1653-1655.
    • (2002) Science , vol.296 , Issue.5573 , pp. 1653-1655
    • Aaronson, D.S.1    Horvath, C.M.2
  • 2
    • 0034671546 scopus 로고    scopus 로고
    • A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b
    • Aoki N, Matsuda T. 2000. A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b. J Biol Chem 275(50):39718-39726.
    • (2000) J Biol Chem , vol.275 , Issue.50 , pp. 39718-39726
    • Aoki, N.1    Matsuda, T.2
  • 3
    • 0036138705 scopus 로고    scopus 로고
    • A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRLmediated signaling pathway: Dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus
    • Aoki N, Matsuda T. 2002. A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRLmediated signaling pathway: dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus. Mol Endocrinol 16(1):58-69.
    • (2002) Mol Endocrinol , vol.16 , Issue.1 , pp. 58-69
    • Aoki, N.1    Matsuda, T.2
  • 4
    • 0028916417 scopus 로고
    • Interleukin-3 signals through multiple isoforms of Stat5
    • Azam M, et al. 1995. Interleukin-3 signals through multiple isoforms of Stat5. EMBO J 14(7):1402-1411.
    • (1995) EMBO J , vol.14 , Issue.7 , pp. 1402-1411
    • Azam, M.1
  • 5
    • 33749241886 scopus 로고    scopus 로고
    • Stat5 in the mammary gland: Controlling normal development and cancer
    • Barash I. 2006. Stat5 in the mammary gland: controlling normal development and cancer. J Cell Physiol 209(2):305-313.
    • (2006) J Cell Physiol , vol.209 , Issue.2 , pp. 305-313
    • Barash, I.1
  • 6
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, et al. 2005. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 365(9464): 1054-1061.
    • (2005) Lancet , vol.365 , Issue.9464 , pp. 1054-1061
    • Baxter, E.J.1
  • 7
    • 0032499801 scopus 로고    scopus 로고
    • Three-Dimensional structure of the Stat3beta homodimer bound to DNA
    • Becker S, Groner B, Muller CW. 1998. Three-dimensional structure of the Stat3beta homodimer bound to DNA. Nature 394(6689):145-151.
    • (1998) Nature , vol.394 , Issue.6689 , pp. 145-151
    • Becker, S.1    Groner, B.2    Muller, C.W.3
  • 8
    • 84895831090 scopus 로고    scopus 로고
    • PAK-Dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis
    • Berger A, et al. 2014. PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis. Leukemia 28(3):629-641.
    • (2014) Leukemia , vol.28 , Issue.3 , pp. 629-641
    • Berger, A.1
  • 9
    • 0029767462 scopus 로고    scopus 로고
    • Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha
    • Bhattacharya S, et al. 1996. Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature 383(6598):344-347.
    • (1996) Nature , vol.383 , Issue.6598 , pp. 344-347
    • Bhattacharya, S.1
  • 10
    • 0037327154 scopus 로고    scopus 로고
    • Regulation of Stat3 nuclear export
    • Bhattacharya S, Schindler C. 2003. Regulation of Stat3 nuclear export. J Clin Invest 111(4):553-559.
    • (2003) J Clin Invest , vol.111 , Issue.4 , pp. 553-559
    • Bhattacharya, S.1    Schindler, C.2
  • 11
    • 0032545456 scopus 로고    scopus 로고
    • A single amino acid in the DNA binding regions of STAT5Aand STAT5B confers distinctDNAbinding specificities
    • Boucheron C, et al. 1998. A single amino acid in the DNA binding regions of STAT5Aand STAT5B confers distinctDNAbinding specificities. J Biol Chem 273(51):33936-33941.
    • (1998) J Biol Chem , vol.273 , Issue.51 , pp. 33936-33941
    • Boucheron, C.1
  • 12
    • 0034658698 scopus 로고    scopus 로고
    • STATs in oncogenesis
    • Bowman T, et al. 2000. STATs in oncogenesis. Oncogene 19(21):2474-2488.
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2474-2488
    • Bowman, T.1
  • 13
    • 84870825008 scopus 로고    scopus 로고
    • JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: A rationale for cotargeting these pathways in metastatic breast cancer
    • Britschgi A, et al. 2012. JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer. Cancer Cell 22(6):796-811.
    • (2012) Cancer Cell , vol.22 , Issue.6 , pp. 796-811
    • Britschgi, A.1
  • 14
    • 0036469065 scopus 로고    scopus 로고
    • Signal transduction and the control of gene expression
    • Brivanlou AH, Darnell JE, Jr. 2002. Signal transduction and the control of gene expression. Science 295(5556):813-818.
    • (2002) Science , vol.295 , Issue.5556 , pp. 813-818
    • Brivanlou, A.H.1    Darnell, Jr.J.E.2
  • 15
    • 0036251154 scopus 로고    scopus 로고
    • Stat proteins and oncogenesis
    • Bromberg J. 2002. Stat proteins and oncogenesis. J Clin Invest 109(9):1139-1142.
    • (2002) J Clin Invest , vol.109 , Issue.9 , pp. 1139-1142
    • Bromberg, J.1
  • 16
    • 56049119340 scopus 로고    scopus 로고
    • Unphosphorylated STATs go nuclear
    • Brown S, Zeidler MP. 2008. Unphosphorylated STATs go nuclear. Curr Opin Genet Dev 18(5):455-460.
    • (2008) Curr Opin Genet Dev , vol.18 , Issue.5 , pp. 455-460
    • Brown, S.1    Zeidler, M.P.2
  • 17
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, Jove R. 2002. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8(4):945-954.
    • (2002) Clin Cancer Res , vol.8 , Issue.4 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 18
    • 33845935950 scopus 로고    scopus 로고
    • IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
    • Burchill MA, et al. 2007. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells. J Immunol 178(1):280-290.
    • (2007) J Immunol , vol.178 , Issue.1 , pp. 280-290
    • Burchill, M.A.1
  • 19
    • 84857053130 scopus 로고    scopus 로고
    • Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signalling, promotes alveologenesis and resistance to cell death, and contributes to tumourigenesis
    • Caffarel MM, et al. 2012. Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signalling, promotes alveologenesis and resistance to cell death, and contributes to tumourigenesis. Cell Death Differ 19(3):511-522.
    • (2012) Cell Death Differ , vol.19 , Issue.3 , pp. 511-522
    • Caffarel, M.M.1
  • 20
    • 84876008261 scopus 로고    scopus 로고
    • Differential contributions of STAT5A and STAT5B to stress protection and tyrosine kinase inhibitor resistance of chronic myeloid leukemia stem/progenitor cells
    • Casetti L, et al. 2013. Differential contributions of STAT5A and STAT5B to stress protection and tyrosine kinase inhibitor resistance of chronic myeloid leukemia stem/progenitor cells. Cancer Res 73(7):2052-2058.
    • (2013) Cancer Res , vol.73 , Issue.7 , pp. 2052-2058
    • Casetti, L.1
  • 21
    • 0032577678 scopus 로고    scopus 로고
    • Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
    • Chen X, et al. 1998. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell 93(5):827-839.
    • (1998) Cell , vol.93 , Issue.5 , pp. 827-839
    • Chen, X.1
  • 22
    • 0037304457 scopus 로고    scopus 로고
    • A reinterpretation of the dimerization interface of the N-terminal domains of STATs
    • Chen X, et al. 2003a. A reinterpretation of the dimerization interface of the N-terminal domains of STATs. Protein Sci 12(2):361-365.
    • (2003) Protein Sci , vol.12 , Issue.2 , pp. 361-365
    • Chen, X.1
  • 23
    • 0037593839 scopus 로고    scopus 로고
    • Identification of Shp-2 as a Stat5A phosphatase
    • Chen Y, et al. 2003b. Identification of Shp-2 as a Stat5A phosphatase. J Biol Chem 278(19):16520-16527.
    • (2003) J Biol Chem , vol.278 , Issue.19 , pp. 16520-16527
    • Chen, Y.1
  • 24
    • 33745937881 scopus 로고    scopus 로고
    • Proteasome-dependent down-regulation of activated Stat5A in the nucleus
    • Chen Y, et al. 2006. Proteasome-dependent down-regulation of activated Stat5A in the nucleus. Blood 108(2):566-574.
    • (2006) Blood , vol.108 , Issue.2 , pp. 566-574
    • Chen, Y.1
  • 25
    • 0037163109 scopus 로고    scopus 로고
    • Prolactin induces SHP-2 association with Stat5, nuclear translocation, and binding to the beta-casein gene promoter in mammary cells
    • Chughtai N, et al. 2002. Prolactin induces SHP-2 association with Stat5, nuclear translocation, and binding to the beta-casein gene promoter in mammary cells. J Biol Chem 277(34): 31107-31114.
    • (2002) J Biol Chem , vol.277 , Issue.34 , pp. 31107-31114
    • Chughtai, N.1
  • 26
    • 21244475659 scopus 로고    scopus 로고
    • ERBB4/HER4 potentiates STAT5A transcriptional activity by regulating novel STAT5A serine phosphorylation events
    • Clark DE, et al. 2005. ERBB4/HER4 potentiates STAT5A transcriptional activity by regulating novel STAT5A serine phosphorylation events. J Biol Chem 280(25):24175-24180.
    • (2005) J Biol Chem , vol.280 , Issue.25 , pp. 24175-24180
    • Clark, D.E.1
  • 27
    • 0029157421 scopus 로고
    • Distribution of the mammalian Stat gene family in mouse chromosomes
    • Copeland NG, et al. 1995. Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics 29(1):225-228.
    • (1995) Genomics , vol.29 , Issue.1 , pp. 225-228
    • Copeland, N.G.1
  • 28
    • 0346024125 scopus 로고    scopus 로고
    • Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers
    • Cotarla I, et al. 2004. Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers. Int J Cancer 108(5):665-671.
    • (2004) Int J Cancer , vol.108 , Issue.5 , pp. 665-671
    • Cotarla, I.1
  • 29
    • 4444268818 scopus 로고    scopus 로고
    • Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation
    • Cui Y, et al. 2004. Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol Cell Biol 24(18):8037-8047.
    • (2004) Mol Cell Biol , vol.24 , Issue.18 , pp. 8037-8047
    • Cui, Y.1
  • 30
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell JE, Jr. 1997. STATs and gene regulation. Science 277(5332):1630-1635.
    • (1997) Science , vol.277 , Issue.5332 , pp. 1630-1635
    • Darnell, Jr.J.E.1
  • 31
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE, Jr., Kerr IM, Stark GR. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264(5164):1415-1421.
    • (1994) Science , vol.264 , Issue.5164 , pp. 1415-1421
    • Darnell, Jr.J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 32
    • 0036108577 scopus 로고    scopus 로고
    • IFNs and STATs in innate immunity to microorganisms
    • Decker T, et al. 2002. IFNs and STATs in innate immunity to microorganisms. J Clin Invest 109(10):1271-1277.
    • (2002) J Clin Invest , vol.109 , Issue.10 , pp. 1271-1277
    • Decker, T.1
  • 33
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of STATs
    • Decker T, Kovarik P. 2000. Serine phosphorylation of STATs. Oncogene 19(21):2628-2637.
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 34
    • 84879936071 scopus 로고    scopus 로고
    • Promotion of osteoblast differentiation in mesenchymal cells through Cbl-mediated control of STAT5 activity
    • Dieudonne FX, et al. 2013. Promotion of osteoblast differentiation in mesenchymal cells through Cbl-mediated control of STAT5 activity. Stem Cells 31(7):1340-1349.
    • (2013) Stem Cells , vol.31 , Issue.7 , pp. 1340-1349
    • Dieudonne, F.X.1
  • 35
    • 0035794217 scopus 로고    scopus 로고
    • DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites
    • Ehret GB, et al. 2001. DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites. J Biol Chem 276(9):6675-6688.
    • (2001) J Biol Chem , vol.276 , Issue.9 , pp. 6675-6688
    • Ehret, G.B.1
  • 36
    • 34249070257 scopus 로고    scopus 로고
    • Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturationrelated gene expression
    • Engblom D, et al. 2007. Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturationrelated gene expression. Genes Dev 21(10):1157-1162.
    • (2007) Genes Dev , vol.21 , Issue.10 , pp. 1157-1162
    • Engblom, D.1
  • 37
    • 77956589191 scopus 로고    scopus 로고
    • Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation
    • Friedbichler K, et al. 2010. Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood 116(9):1548-1558.
    • (2010) Blood , vol.116 , Issue.9 , pp. 1548-1558
    • Friedbichler, K.1
  • 38
    • 0032799029 scopus 로고    scopus 로고
    • Activation of STAT5 by IL-4 relies on Janus kinase function but not on receptor tyrosine phosphorylation, and can contribute to both cell proliferation and gene regulation
    • Friedrich K, et al. 1999. Activation of STAT5 by IL-4 relies on Janus kinase function but not on receptor tyrosine phosphorylation, and can contribute to both cell proliferation and gene regulation. Int Immunol 11(8):1283-1294.
    • (1999) Int Immunol , vol.11 , Issue.8 , pp. 1283-1294
    • Friedrich, K.1
  • 39
    • 22744450774 scopus 로고    scopus 로고
    • IL-2-and STAT5-regulated cytokine gene expression in cells expressing the Tax protein of HTLV-1
    • Fung MM, et al. 2005. IL-2-and STAT5-regulated cytokine gene expression in cells expressing the Tax protein of HTLV-1. Oncogene 24(29):4624-4633.
    • (2005) Oncogene , vol.24 , Issue.29 , pp. 4624-4633
    • Fung, M.M.1
  • 40
    • 33845972945 scopus 로고    scopus 로고
    • Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: Results of a long-term survey
    • Germeshausen M, Ballmaier M, Welte K. 2007. Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: results of a long-term survey. Blood 109(1):93-99.
    • (2007) Blood , vol.109 , Issue.1 , pp. 93-99
    • Germeshausen, M.1    Ballmaier, M.2    Welte, K.3
  • 41
    • 0942287200 scopus 로고    scopus 로고
    • The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5
    • Gewinner C, et al. 2004. The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5. J Biol Chem 279(5):3563-3572.
    • (2004) J Biol Chem , vol.279 , Issue.5 , pp. 3563-3572
    • Gewinner, C.1
  • 42
    • 0033168958 scopus 로고    scopus 로고
    • P300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6
    • Gingras S, et al. 1999. p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6. Nucleic Acids Res 27(13):2722-2729.
    • (1999) Nucleic Acids Res , vol.27 , Issue.13 , pp. 2722-2729
    • Gingras, S.1
  • 43
    • 0031408534 scopus 로고    scopus 로고
    • Activated Stat related transcription factors in acute leukemia
    • Gouilleux-Gruart V, et al. 1997. Activated Stat related transcription factors in acute leukemia. Leuk Lymphoma 28(1-2):83-88.
    • (1997) Leuk Lymphoma , vol.28 , Issue.1-2 , pp. 83-88
    • Gouilleux-Gruart, V.1
  • 44
    • 0033883449 scopus 로고    scopus 로고
    • Regulation of the trans-activation potential of STAT5 through its DNA-binding activity and interactions with heterologous transcription factors
    • Groner B, et al. 2000. Regulation of the trans-activation potential of STAT5 through its DNA-binding activity and interactions with heterologous transcription factors. Growth Horm IGF Res 10 Suppl B:S15-S20.
    • (2000) Growth Horm IGF Res , vol.10 , pp. S15-S20
    • Groner, B.1
  • 45
    • 34347207060 scopus 로고    scopus 로고
    • SFK-STAT pathway: An alternative and important way to malignancies
    • Hayakawa F, Naoe T. 2006. SFK-STAT pathway: an alternative and important way to malignancies. Ann N Y Acad Sci 1086:213-222.
    • (2006) Ann N y Acad Sci , vol.1086 , pp. 213-222
    • Hayakawa, F.1    Naoe, T.2
  • 46
    • 4344672552 scopus 로고    scopus 로고
    • Imatinib therapy in chronic myelogenous leukemia: Strategies to avoid and overcome resistance
    • Hochhaus A, La Rosee P. 2004. Imatinib therapy in chronic myelogenous leukemia: strategies to avoid and overcome resistance. Leukemia 18(8):1321-1331.
    • (2004) Leukemia , vol.18 , Issue.8 , pp. 1321-1331
    • Hochhaus, A.1    La Rosee, P.2
  • 47
    • 33745111882 scopus 로고    scopus 로고
    • Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation
    • Hoelbl A, et al. 2006. Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation. Blood 107(12):4898-4906.
    • (2006) Blood , vol.107 , Issue.12 , pp. 4898-4906
    • Hoelbl, A.1
  • 48
    • 0034306290 scopus 로고    scopus 로고
    • STAT proteins and transcriptional responses to extracellular signals
    • Horvath CM. 2000. STAT proteins and transcriptional responses to extracellular signals. Trends Biochem Sci 25(10): 496-502.
    • (2000) Trends Biochem Sci , vol.25 , Issue.10 , pp. 496-502
    • Horvath, C.M.1
  • 49
    • 0028913109 scopus 로고
    • A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
    • Horvath CM, Wen Z, Darnell JE, Jr. 1995. A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev 9(8):984-994.
    • (1995) Genes Dev , vol.9 , Issue.8 , pp. 984-994
    • Horvath, C.M.1    Wen, Z.2    Darnell, J.E.3
  • 50
    • 35748980594 scopus 로고    scopus 로고
    • Cutting edge: Selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphatase
    • Hoyt R, et al. 2007. Cutting edge: selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphatase. J Immunol 179(6):3402-3406.
    • (2007) J Immunol , vol.179 , Issue.6 , pp. 3402-3406
    • Hoyt, R.1
  • 51
    • 0032713453 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 5a influences mammary epithelial cell survival and tumorigenesis
    • Humphreys RC, Hennighausen L. 1999. Signal transducer and activator of transcription 5a influences mammary epithelial cell survival and tumorigenesis. Cell Growth Differ 10(10): 685-694.
    • (1999) Cell Growth Differ , vol.10 , Issue.10 , pp. 685-694
    • Humphreys, R.C.1    Hennighausen, L.2
  • 52
    • 7044272580 scopus 로고    scopus 로고
    • Deregulation of Stat5 expression and activation causes mammary tumors in transgenic mice
    • Iavnilovitch E, et al. 2004. Deregulation of Stat5 expression and activation causes mammary tumors in transgenic mice. Int J Cancer 112(4):607-619.
    • (2004) Int J Cancer , vol.112 , Issue.4 , pp. 607-619
    • Iavnilovitch, E.1
  • 53
    • 0345700700 scopus 로고    scopus 로고
    • Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis
    • Iavnilovitch E, Groner B, Barash I. 2002. Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis. Mol Cancer Res 1(1):32-47.
    • (2002) Mol Cancer Res , vol.1 , Issue.1 , pp. 32-47
    • Iavnilovitch, E.1    Groner, B.2    Barash, I.3
  • 54
    • 0030088077 scopus 로고    scopus 로고
    • STATs and MAPKs: Obligate or opportunistic partners in signaling
    • Ihle JN. 1996. STATs and MAPKs: obligate or opportunistic partners in signaling. Bioessays 18(2):95-98.
    • (1996) Bioessays , vol.18 , Issue.2 , pp. 95-98
    • Ihle, J.N.1
  • 55
    • 0000506439 scopus 로고    scopus 로고
    • P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members
    • Ilaria RL, Jr., Van Etten RA. 1996. P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members. J Biol Chem 271(49):31704-31710.
    • (1996) J Biol Chem , vol.271 , Issue.49 , pp. 31704-31710
    • Ilaria, Jr.R.L.1    Van Etten, R.A.2
  • 56
    • 0031774896 scopus 로고    scopus 로고
    • Stat5b is essential for natural killer cellmediated proliferation and cytolytic activity
    • Imada K, et al. 1998. Stat5b is essential for natural killer cellmediated proliferation and cytolytic activity. J Exp Med 188(11):2067-2074.
    • (1998) J Exp Med , vol.188 , Issue.11 , pp. 2067-2074
    • Imada, K.1
  • 57
    • 0035576737 scopus 로고    scopus 로고
    • A new RING for SUMO: Wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases
    • Jackson PK. 2001. A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases. Genes Dev 15(23):3053-3058.
    • (2001) Genes Dev , vol.15 , Issue.23 , pp. 3053-3058
    • Jackson, P.K.1
  • 58
    • 0033019051 scopus 로고    scopus 로고
    • The significance of tetramerization in promoter recruitment by Stat5
    • John S, et al. 1999. The significance of tetramerization in promoter recruitment by Stat5. Mol Cell Biol 19(3): 1910-1918.
    • (1999) Mol Cell Biol , vol.19 , Issue.3 , pp. 1910-1918
    • John, S.1
  • 59
    • 33746859330 scopus 로고    scopus 로고
    • Constitutive STAT5 activation specifically cooperates with the loss of p53 function in B-cell lymphomagenesis
    • Joliot V, et al. 2006. Constitutive STAT5 activation specifically cooperates with the loss of p53 function in B-cell lymphomagenesis. Oncogene 25(33):4573-4584.
    • (2006) Oncogene , vol.25 , Issue.33 , pp. 4573-4584
    • Joliot, V.1
  • 60
    • 0034651636 scopus 로고    scopus 로고
    • Both stat5a and stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue
    • Kagami S, et al. 2000. Both stat5a and stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue. Blood 95(4):1370-1377.
    • (2000) Blood , vol.95 , Issue.4 , pp. 1370-1377
    • Kagami, S.1
  • 61
    • 0033529715 scopus 로고    scopus 로고
    • Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A
    • Kazansky AV, et al. 1999. Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A. J Biol Chem 274(32):22484-22492.
    • (1999) J Biol Chem , vol.274 , Issue.32 , pp. 22484-22492
    • Kazansky, A.V.1
  • 62
    • 0037218561 scopus 로고    scopus 로고
    • A role for Stat5 in CD8+ T cell homeostasis
    • Kelly J, et al. 2003. A role for Stat5 in CD8+ T cell homeostasis. J Immunol 170(1):210-217.
    • (2003) J Immunol , vol.170 , Issue.1 , pp. 210-217
    • Kelly, J.1
  • 63
    • 0030983551 scopus 로고    scopus 로고
    • Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes
    • Kirken RA, et al. 1997. Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes. J Biol Chem 272(22):14098-14103.
    • (1997) J Biol Chem , vol.272 , Issue.22 , pp. 14098-14103
    • Kirken, R.A.1
  • 64
    • 0037138370 scopus 로고    scopus 로고
    • Signaling through the JAK/STAT pathway, recent advances and future challenges
    • Kisseleva T, et al. 2002. Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285(1-2): 1-24.
    • (2002) Gene , vol.285 , Issue.1-2 , pp. 1-24
    • Kisseleva, T.1
  • 65
    • 0029909493 scopus 로고    scopus 로고
    • Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene
    • Lecine P, et al. 1996. Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene. Mol Cell Biol 16(12):6829-6840.
    • (1996) Mol Cell Biol , vol.16 , Issue.12 , pp. 6829-6840
    • Lecine, P.1
  • 66
    • 0035315880 scopus 로고    scopus 로고
    • Role of Jak kinases and STATs in cytokine signal transduction
    • Leonard WJ. 2001. Role of Jak kinases and STATs in cytokine signal transduction. Int J Hematol 73(3):271-277.
    • (2001) Int J Hematol , vol.73 , Issue.3 , pp. 271-277
    • Leonard, W.J.1
  • 67
    • 0029741304 scopus 로고    scopus 로고
    • STATs find that hanging together can be stimulating
    • Leung S, Li X, Stark GR. 1996. STATs find that hanging together can be stimulating. Science 273(5276):750-751.
    • (1996) Science , vol.273 , Issue.5276 , pp. 750-751
    • Leung, S.1    Li, X.2    Stark, G.R.3
  • 68
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, et al. 2005. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 7(4):387-397.
    • (2005) Cancer Cell , vol.7 , Issue.4 , pp. 387-397
    • Levine, R.L.1
  • 69
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • Levy DE, Darnell JE, Jr. 2002. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 3(9):651-662.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.9 , pp. 651-662
    • Levy, D.E.1    Darnell, Jr.J.E.2
  • 70
    • 54549103162 scopus 로고    scopus 로고
    • Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression
    • Liao W, et al. 2008. Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression. Nat Immunol 9(11):1288-1296.
    • (2008) Nat Immunol , vol.9 , Issue.11 , pp. 1288-1296
    • Liao, W.1
  • 71
    • 79956085895 scopus 로고    scopus 로고
    • Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages
    • Liao W, et al. 2011. Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat Immunol 12(6):551-559.
    • (2011) Nat Immunol , vol.12 , Issue.6 , pp. 551-559
    • Liao, W.1
  • 72
    • 84859968982 scopus 로고    scopus 로고
    • Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function
    • Lin JX, et al. 2012. Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function. Immunity 36(4):586-599.
    • (2012) Immunity , vol.36 , Issue.4 , pp. 586-599
    • Lin, J.X.1
  • 73
    • 0034657396 scopus 로고    scopus 로고
    • The role of Stat5a and Stat5b in signaling by IL-2 family cytokines
    • Lin JX, Leonard WJ. 2000. The role of Stat5a and Stat5b in signaling by IL-2 family cytokines. Oncogene 19(21):2566-2576.
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2566-2576
    • Lin, J.X.1    Leonard, W.J.2
  • 74
    • 0034658153 scopus 로고    scopus 로고
    • STAT signaling in the pathogenesis and treatment of leukemias
    • Lin TS, Mahajan S, Frank DA. 2000. STAT signaling in the pathogenesis and treatment of leukemias. Oncogene 19(21): 2496-2504.
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2496-2504
    • Lin, T.S.1    Mahajan, S.2    Frank, D.A.3
  • 75
    • 0242664926 scopus 로고    scopus 로고
    • NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alphahelical region of the STAT5 transactivation domain
    • Litterst CM, et al. 2003. NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alphahelical region of the STAT5 transactivation domain. J Biol Chem 278(46):45340-45351.
    • (2003) J Biol Chem , vol.278 , Issue.46 , pp. 45340-45351
    • Litterst, C.M.1
  • 76
    • 0029115640 scopus 로고
    • Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue
    • Liu X, et al. 1995. Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue. Proc Natl Acad Sci USA 92(19):8831-8835.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.19 , pp. 8831-8835
    • Liu, X.1
  • 77
    • 0031057929 scopus 로고    scopus 로고
    • Stat5a is mandatory for adult mammary gland development and lactogenesis
    • Liu X, et al. 1997. Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev 11(2):179-186.
    • (1997) Genes Dev , vol.11 , Issue.2 , pp. 179-186
    • Liu, X.1
  • 78
    • 0029906982 scopus 로고    scopus 로고
    • Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation
    • Liu X, Robinson GW, Hennighausen L. 1996. Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation. Mol Endocrinol 10(12):1496-1506.
    • (1996) Mol Endocrinol , vol.10 , Issue.12 , pp. 1496-1506
    • Liu, X.1    Robinson, G.W.2    Hennighausen, L.3
  • 79
    • 0029557904 scopus 로고
    • Stat1 depends on transcriptional synergy with Sp1
    • Look DC, et al. 1995. Stat1 depends on transcriptional synergy with Sp1. J Biol Chem 270(51):30264-30267.
    • (1995) J Biol Chem , vol.270 , Issue.51 , pp. 30264-30267
    • Look, D.C.1
  • 80
    • 3042552337 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1
    • Marg A, et al. 2004. Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1. J Cell Biol 165(6):823-833.
    • (2004) J Cell Biol , vol.165 , Issue.6 , pp. 823-833
    • Marg, A.1
  • 81
    • 0029909494 scopus 로고    scopus 로고
    • Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons
    • Meinke A, et al. 1996. Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons. Mol Cell Biol 16(12):6937-6944.
    • (1996) Mol Cell Biol , vol.16 , Issue.12 , pp. 6937-6944
    • Meinke, A.1
  • 82
    • 2442577024 scopus 로고    scopus 로고
    • A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of stat transcription factors
    • Meyer T, et al. 2004. A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of stat transcription factors. J Biol Chem 279(18):18998-19007.
    • (2004) J Biol Chem , vol.279 , Issue.18 , pp. 18998-19007
    • Meyer, T.1
  • 83
    • 0031467318 scopus 로고    scopus 로고
    • Interaction of STAT5 dimers on two low affinity binding sites mediates interleukin 2 (IL-2) stimulation of IL-2 receptor alpha gene transcription
    • Meyer WK, et al. 1997. Interaction of STAT5 dimers on two low affinity binding sites mediates interleukin 2 (IL-2) stimulation of IL-2 receptor alpha gene transcription. J Biol Chem 272(50):31821-31828.
    • (1997) J Biol Chem , vol.272 , Issue.50 , pp. 31821-31828
    • Meyer, W.K.1
  • 84
    • 0029790559 scopus 로고    scopus 로고
    • Requirements for interleukin-4-induced gene expression and functional characterization of Stat6
    • Mikita T, et al. 1996. Requirements for interleukin-4-induced gene expression and functional characterization of Stat6. Mol Cell Biol 16(10):5811-5820.
    • (1996) Mol Cell Biol , vol.16 , Issue.10 , pp. 5811-5820
    • Mikita, T.1
  • 85
    • 0346059585 scopus 로고    scopus 로고
    • Dysregulated expression of COOH-terminally truncated Stat5 and loss of IL2-inducible Stat5-dependent gene expression in Sezary Syndrome
    • Mitchell TJ, Whittaker SJ, John S. 2003. Dysregulated expression of COOH-terminally truncated Stat5 and loss of IL2-inducible Stat5-dependent gene expression in Sezary Syndrome. Cancer Res 63(24):9048-9054.
    • (2003) Cancer Res , vol.63 , Issue.24 , pp. 9048-9054
    • Mitchell, T.J.1    Whittaker, S.J.2    John, S.3
  • 86
    • 0035969246 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium
    • Miyoshi K, et al. 2001. Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium. J Cell Biol 155(4): 531-542.
    • (2001) J Cell Biol , vol.155 , Issue.4 , pp. 531-542
    • Miyoshi, K.1
  • 87
    • 3843106113 scopus 로고    scopus 로고
    • Oncogenic receptor tyrosine kinase in leukemia
    • Mizuki M, et al. 2003. Oncogenic receptor tyrosine kinase in leukemia. Cell Mol Biol (Noisy-le-grand) 49(6):907-922.
    • (2003) Cell Mol Biol (Noisy-le-grand) , vol.49 , Issue.6 , pp. 907-922
    • Mizuki, M.1
  • 88
    • 0033082138 scopus 로고    scopus 로고
    • Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
    • Moriggl R, et al. 1999. Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 10(2): 249-259.
    • (1999) Immunity , vol.10 , Issue.2 , pp. 249-259
    • Moriggl, R.1
  • 89
    • 19944431828 scopus 로고    scopus 로고
    • Stat5 tetramer formation is associated with leukemogenesis
    • Moriggl R, et al. 2005. Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell 7(1):87-99.
    • (2005) Cancer Cell , vol.7 , Issue.1 , pp. 87-99
    • Moriggl, R.1
  • 90
    • 0032006255 scopus 로고    scopus 로고
    • Activation of theMHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1
    • Muhlethaler-Mottet A, et al. 1998. Activation of theMHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1. Immunity 8(2):157-166.
    • (1998) Immunity , vol.8 , Issue.2 , pp. 157-166
    • Muhlethaler-Mottet, A.1
  • 91
    • 0029045866 scopus 로고
    • Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5
    • Mui AL, et al. 1995. Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5. J Leukoc Biol 57(5):799-803.
    • (1995) J Leukoc Biol , vol.57 , Issue.5 , pp. 799-803
    • Mui, A.L.1
  • 92
    • 0033835830 scopus 로고    scopus 로고
    • Role of the Stat4 N domain in receptor proximal tyrosine phosphorylation
    • Murphy TL, et al. 2000. Role of the Stat4 N domain in receptor proximal tyrosine phosphorylation. Mol Cell Biol 20(19):7121-7131.
    • (2000) Mol Cell Biol , vol.20 , Issue.19 , pp. 7121-7131
    • Murphy, T.L.1
  • 93
    • 33744975816 scopus 로고    scopus 로고
    • Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5
    • Mziaut H, et al. 2006. Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5. Nat Cell Biol 8(5):435-445.
    • (2006) Nat Cell Biol , vol.8 , Issue.5 , pp. 435-445
    • Mziaut, H.1
  • 94
    • 0031433362 scopus 로고    scopus 로고
    • An indirect effect of Stat5a in IL-2-induced proliferation: A critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction
    • Nakajima H, et al. 1997. An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction. Immunity 7(5): 691-701.
    • (1997) Immunity , vol.7 , Issue.5 , pp. 691-701
    • Nakajima, H.1
  • 95
    • 61849105375 scopus 로고    scopus 로고
    • BLNK suppresses pre-B-cell leukemogenesis through inhibition of JAK3
    • Nakayama J, et al. 2009. BLNK suppresses pre-B-cell leukemogenesis through inhibition of JAK3. Blood 113(7):1483-1492.
    • (2009) Blood , vol.113 , Issue.7 , pp. 1483-1492
    • Nakayama, J.1
  • 96
    • 30044432207 scopus 로고    scopus 로고
    • Nuclear localization of STAT5A modified with O-linked N-acetylglucosamine and early involution in the mammary gland of Hirosaki hairless rat
    • Nanashima N, et al. 2005. Nuclear localization of STAT5A modified with O-linked N-acetylglucosamine and early involution in the mammary gland of Hirosaki hairless rat. J Biol Chem 280(52):43010-43016.
    • (2005) J Biol Chem , vol.280 , Issue.52 , pp. 43010-43016
    • Nanashima, N.1
  • 97
    • 2942672845 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription-5 activation and breast cancer prognosis
    • Nevalainen MT, et al. 2004. Signal transducer and activator of transcription-5 activation and breast cancer prognosis. J Clin Oncol 22(11):2053-2060.
    • (2004) J Clin Oncol , vol.22 , Issue.11 , pp. 2053-2060
    • Nevalainen, M.T.1
  • 98
    • 0033758397 scopus 로고    scopus 로고
    • Jaks and stats as therapeutic targets
    • O'Shea JJ, et al. 2000. Jaks and stats as therapeutic targets. Ann Rheum Dis 59 Suppl 1:i115-i118.
    • (2000) Ann Rheum Dis , vol.59 , pp. i115-i118
    • O'Shea, J.J.1
  • 99
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
    • O'Shea JJ, Gadina M, Schreiber RD. 2002. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109 Suppl:S121-S131.
    • (2002) Cell , vol.109 , pp. S121-S131
    • O'Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 100
    • 0031836964 scopus 로고    scopus 로고
    • Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation
    • Onishi M, et al. 1998. Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation. Mol Cell Biol 18(7):3871-3879.
    • (1998) Mol Cell Biol , vol.18 , Issue.7 , pp. 3871-3879
    • Onishi, M.1
  • 101
    • 34548748171 scopus 로고    scopus 로고
    • Coreceptor tuning': Cytokine signals transcriptionally tailor CD8 coreceptor expression to the selfspecificity of the TCR
    • Park JH, et al. 2007. 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the selfspecificity of the TCR. Nat Immunol 8(10):1049-1059.
    • (2007) Nat Immunol , vol.8 , Issue.10 , pp. 1049-1059
    • Park, J.H.1
  • 102
    • 0035900726 scopus 로고    scopus 로고
    • Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: Impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression
    • Park SH, Waxman DJ. 2001. Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression. J Biol Chem 276(46):43031-43039.
    • (2001) J Biol Chem , vol.276 , Issue.46 , pp. 43031-43039
    • Park, S.H.1    Waxman, D.J.2
  • 103
    • 79959309120 scopus 로고    scopus 로고
    • Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure
    • Peck AR, et al. 2011. Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure. J Clin Oncol 29(18):2448-2458.
    • (2011) J Clin Oncol , vol.29 , Issue.18 , pp. 2448-2458
    • Peck, A.R.1
  • 104
    • 0034650951 scopus 로고    scopus 로고
    • Interleukin-4-induced transcriptional activation by stat6 involvesmultiple serine/threonine kinase pathways and serine phosphorylation of stat6
    • Pesu M, et al. 2000. Interleukin-4-induced transcriptional activation by stat6 involvesmultiple serine/threonine kinase pathways and serine phosphorylation of stat6. Blood 95(2):494-502.
    • (2000) Blood , vol.95 , Issue.2 , pp. 494-502
    • Pesu, M.1
  • 105
    • 0032230282 scopus 로고    scopus 로고
    • P300/CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in the Stat5-mediated suppression of the glucocorticoid response
    • Pfitzner E, et al. 1998. p300/CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in the Stat5-mediated suppression of the glucocorticoid response. Mol Endocrinol 12(10):1582-1593.
    • (1998) Mol Endocrinol , vol.12 , Issue.10 , pp. 1582-1593
    • Pfitzner, E.1
  • 106
    • 0037071409 scopus 로고    scopus 로고
    • JAKs, STATs and Src kinases in hematopoiesis
    • Rane SG, Reddy EP. 2002. JAKs, STATs and Src kinases in hematopoiesis. Oncogene 21(21):3334-3358.
    • (2002) Oncogene , vol.21 , Issue.21 , pp. 3334-3358
    • Rane, S.G.1    Reddy, E.P.2
  • 107
    • 42149188212 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells
    • Rathinam C, et al. 2008. The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells. Genes Dev 22(8):992-997.
    • (2008) Genes Dev , vol.22 , Issue.8 , pp. 992-997
    • Rathinam, C.1
  • 108
    • 0037142617 scopus 로고    scopus 로고
    • Loss of Stat5a delays mammary cancer progression in a mouse model
    • Ren S, et al. 2002. Loss of Stat5a delays mammary cancer progression in a mouse model. Oncogene 21(27):4335-4339.
    • (2002) Oncogene , vol.21 , Issue.27 , pp. 4335-4339
    • Ren, S.1
  • 109
    • 0037076393 scopus 로고    scopus 로고
    • The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer
    • Rycyzyn MA, Clevenger CV. 2002. The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer. Proc Natl Acad Sci USA 99(10):6790-6795.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.10 , pp. 6790-6795
    • Rycyzyn, M.A.1    Clevenger, C.V.2
  • 110
    • 24644512928 scopus 로고    scopus 로고
    • Nuclear retention of STAT3 through the coiled-coil domain regulates its activity
    • Sato N, et al. 2005. Nuclear retention of STAT3 through the coiled-coil domain regulates its activity. Biochem Biophys Res Commun 336(2):617-624.
    • (2005) Biochem Biophys Res Commun , vol.336 , Issue.2 , pp. 617-624
    • Sato, N.1
  • 111
    • 0029075875 scopus 로고
    • Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3
    • Schaefer TS, Sanders LK, Nathans D. 1995. Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3. Proc Natl Acad Sci USA 92(20):9097-9101.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.20 , pp. 9097-9101
    • Schaefer, T.S.1    Sanders, L.K.2    Nathans, D.3
  • 112
    • 84901290824 scopus 로고    scopus 로고
    • BCR-ABL affects STAT5A and STAT5B differentially
    • Schaller-Schonitz M, et al. 2014. BCR-ABL affects STAT5A and STAT5B differentially. PLoS One 9(5):e97243.
    • (2014) PLoS One , vol.9 , Issue.5 , pp. e97243
    • Schaller-Schonitz, M.1
  • 113
    • 0026770248 scopus 로고
    • Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
    • Schindler C, et al. 1992. Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257(5071):809-813.
    • (1992) Science , vol.257 , Issue.5071 , pp. 809-813
    • Schindler, C.1
  • 114
    • 0345575181 scopus 로고    scopus 로고
    • Cytokines and STAT signaling
    • Schindler C, Strehlow I. 2000. Cytokines and STAT signaling. Adv Pharmacol 47:113-174.
    • (2000) Adv Pharmacol , vol.47 , pp. 113-174
    • Schindler, C.1    Strehlow, I.2
  • 115
    • 0036256836 scopus 로고    scopus 로고
    • Series introduction. JAK-STAT signaling in human disease
    • Schindler CW. 2002. Series introduction. JAK-STAT signaling in human disease. J Clin Invest 109(9):1133-1137.
    • (2002) J Clin Invest , vol.109 , Issue.9 , pp. 1133-1137
    • Schindler, C.W.1
  • 116
    • 0028937707 scopus 로고
    • Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity
    • Seidel HM, et al. 1995. Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity. Proc Natl Acad Sci USA 92(7):3041-3045.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.7 , pp. 3041-3045
    • Seidel, H.M.1
  • 117
    • 0034665676 scopus 로고    scopus 로고
    • Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl-and bcr/abl-induced transformation are independent of stat5
    • Sexl V, et al. 2000. Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl-and bcr/abl-induced transformation are independent of stat5. Blood 96(6):2277-2283.
    • (2000) Blood , vol.96 , Issue.6 , pp. 2277-2283
    • Sexl, V.1
  • 118
    • 0034657917 scopus 로고    scopus 로고
    • Modulation of STAT signaling by STATinteracting proteins
    • Shuai K. 2000. Modulation of STAT signaling by STATinteracting proteins. Oncogene 19(21):2638-2644.
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2638-2644
    • Shuai, K.1
  • 119
    • 0027090310 scopus 로고
    • Activation of transcription by IFN-gamma: Tyrosine phosphorylation of a 91-kD DNA binding protein
    • Shuai K, et al. 1992. Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science 258(5089):1808-1812.
    • (1992) Science , vol.258 , Issue.5089 , pp. 1808-1812
    • Shuai, K.1
  • 120
    • 0029810923 scopus 로고    scopus 로고
    • Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia
    • Shuai K, et al. 1996. Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia. Oncogene 13(2):247-254.
    • (1996) Oncogene , vol.13 , Issue.2 , pp. 247-254
    • Shuai, K.1
  • 121
    • 34347229109 scopus 로고    scopus 로고
    • Integration of steroid and growth factor pathways in breast cancer: Focus on signal transducers and activators of transcription and their potential role in resistance
    • Silva CM, Shupnik MA. 2007. Integration of steroid and growth factor pathways in breast cancer: focus on signal transducers and activators of transcription and their potential role in resistance. Mol Endocrinol 21(7):1499-1512.
    • (2007) Mol Endocrinol , vol.21 , Issue.7 , pp. 1499-1512
    • Silva, C.M.1    Shupnik, M.A.2
  • 122
    • 0036098153 scopus 로고    scopus 로고
    • STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells
    • Snow JW, et al. 2002. STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells. Blood 99(1):95-101.
    • (2002) Blood , vol.99 , Issue.1 , pp. 95-101
    • Snow, J.W.1
  • 123
    • 26844432215 scopus 로고    scopus 로고
    • The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation
    • Snyder M, He W, Zhang JJ. 2005. The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation. Proc Natl Acad Sci USA 102(41):14539-14544.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.41 , pp. 14539-14544
    • Snyder, M.1    He, W.2    Zhang, J.J.3
  • 124
    • 0033988447 scopus 로고    scopus 로고
    • DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites
    • Soldaini E, et al. 2000. DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites. Mol Cell Biol 20(1):389-401.
    • (2000) Mol Cell Biol , vol.20 , Issue.1 , pp. 389-401
    • Soldaini, E.1
  • 125
    • 0029851231 scopus 로고    scopus 로고
    • Functional interactions between Stat5 and the glucocorticoid receptor
    • Stocklin E, et al. 1996. Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383(6602):726-728.
    • (1996) Nature , vol.383 , Issue.6602 , pp. 726-728
    • Stocklin, E.1
  • 126
    • 13444263403 scopus 로고    scopus 로고
    • Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells
    • Sultan AS, et al. 2005. Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells. Oncogene 24(5):746-760.
    • (2005) Oncogene , vol.24 , Issue.5 , pp. 746-760
    • Sultan, A.S.1
  • 127
    • 0034046605 scopus 로고    scopus 로고
    • STAT family of transcription factors in cytokine-mediated biological responses
    • Takeda K, Akira S. 2000. STAT family of transcription factors in cytokine-mediated biological responses. Cytokine Growth Factor Rev 11(3):199-207.
    • (2000) Cytokine Growth Factor Rev , vol.11 , Issue.3 , pp. 199-207
    • Takeda, K.1    Akira, S.2
  • 128
    • 9144244169 scopus 로고    scopus 로고
    • FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
    • Taketani T, et al. 2004. FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy. Blood 103(3):1085-1088.
    • (2004) Blood , vol.103 , Issue.3 , pp. 1085-1088
    • Taketani, T.1
  • 129
    • 45849116295 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 5A/B in prostate and breast cancers
    • Tan SH, Nevalainen MT. 2008. Signal transducer and activator of transcription 5A/B in prostate and breast cancers. Endocr Relat Cancer 15(2):367-390.
    • (2008) Endocr Relat Cancer , vol.15 , Issue.2 , pp. 367-390
    • Tan, S.H.1    Nevalainen, M.T.2
  • 130
    • 73649093445 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription (STAT)-5A and STAT5B differentially regulate human mammary carcinoma cell behavior
    • Tang JZ, et al. 2010. Signal transducer and activator of transcription (STAT)-5A and STAT5B differentially regulate human mammary carcinoma cell behavior. Endocrinology 151(1):43-55.
    • (2010) Endocrinology , vol.151 , Issue.1 , pp. 43-55
    • Tang, J.Z.1
  • 131
    • 0000943469 scopus 로고    scopus 로고
    • Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
    • Teglund S, et al. 1998. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell 93(5):841-850.
    • (1998) Cell , vol.93 , Issue.5 , pp. 841-850
    • Teglund, S.1
  • 132
    • 0029152254 scopus 로고
    • Activation of STAT factors by prolactin, interferon-gamma, growth hormones, and a tyrosine phosphatase inhibitor in rabbit primary mammary epithelial cells
    • Tourkine N, et al. 1995. Activation of STAT factors by prolactin, interferon-gamma, growth hormones, and a tyrosine phosphatase inhibitor in rabbit primary mammary epithelial cells. J Biol Chem 270(36):20952-20961.
    • (1995) J Biol Chem , vol.270 , Issue.36 , pp. 20952-20961
    • Tourkine, N.1
  • 133
    • 76749106107 scopus 로고    scopus 로고
    • Prolactin inhibits BCL6 expression in breast cancer through a Stat5a-dependent mechanism
    • Tran TH, et al. 2010. Prolactin inhibits BCL6 expression in breast cancer through a Stat5a-dependent mechanism. Cancer Res 70(4):1711-1721.
    • (2010) Cancer Res , vol.70 , Issue.4 , pp. 1711-1721
    • Tran, T.H.1
  • 134
    • 33644510417 scopus 로고    scopus 로고
    • Association between plasma prolactin concentrations and risk of breast cancer among predominately premenopausal women
    • Tworoger SS, Sluss P, Hankinson SE. 2006. Association between plasma prolactin concentrations and risk of breast cancer among predominately premenopausal women. Cancer Res 66(4):2476-2482.
    • (2006) Cancer Res , vol.66 , Issue.4 , pp. 2476-2482
    • Tworoger, S.S.1    Sluss, P.2    Hankinson, S.E.3
  • 135
    • 0030833570 scopus 로고    scopus 로고
    • Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression
    • Udy GB, et al. 1997. Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression. Proc Natl Acad Sci USA 94(14):7239-7244.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.14 , pp. 7239-7244
    • Udy, G.B.1
  • 136
    • 77952361681 scopus 로고    scopus 로고
    • Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation
    • Vafaizadeh V, et al. 2010. Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation. Stem Cells 28(5):928-938.
    • (2010) Stem Cells , vol.28 , Issue.5 , pp. 928-938
    • Vafaizadeh, V.1
  • 137
    • 35348834097 scopus 로고    scopus 로고
    • Aberrant cytokine signaling in leukemia
    • Van Etten RA. 2007a. Aberrant cytokine signaling in leukemia. Oncogene 26(47):6738-6749.
    • (2007) Oncogene , vol.26 , Issue.47 , pp. 6738-6749
    • Van Etten, R.A.1
  • 138
    • 33947376040 scopus 로고    scopus 로고
    • Oncogenic signaling: New insights and controversies from chronic myeloid leukemia
    • Van Etten RA. 2007b. Oncogenic signaling: new insights and controversies from chronic myeloid leukemia. J Exp Med 204(3):461-465.
    • (2007) J Exp Med , vol.204 , Issue.3 , pp. 461-465
    • Van Etten, R.A.1
  • 139
    • 84863393395 scopus 로고    scopus 로고
    • SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation
    • Van Nguyen T, et al. 2012. SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation. Mol Cell 45(2):210-221.
    • (2012) Mol Cell , vol.45 , Issue.2 , pp. 210-221
    • Van Nguyen, T.1
  • 140
    • 17944383969 scopus 로고    scopus 로고
    • A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: A distinct biochemical difference between STAT5A and STAT5B
    • Verdier F, et al. 1998. A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: a distinct biochemical difference between STAT5A and STAT5B. Mol Cell Biol 18(10):5852-5860.
    • (1998) Mol Cell Biol , vol.18 , Issue.10 , pp. 5852-5860
    • Verdier, F.1
  • 141
    • 0029903770 scopus 로고    scopus 로고
    • DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: Interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites
    • Vinkemeier U, et al. 1996. DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites. EMBO J 15(20):5616-5626.
    • (1996) EMBO J , vol.15 , Issue.20 , pp. 5616-5626
    • Vinkemeier, U.1
  • 142
    • 0032512661 scopus 로고    scopus 로고
    • Structure of the amino-terminal protein interaction domain of STAT-4
    • Vinkemeier U, et al. 1998. Structure of the amino-terminal protein interaction domain of STAT-4. Science 279(5353):1048-1052.
    • (1998) Science , vol.279 , Issue.5353 , pp. 1048-1052
    • Vinkemeier, U.1
  • 143
    • 40449135440 scopus 로고    scopus 로고
    • Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression
    • Wagner KU, Rui H. 2008. Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression. J Mammary Gland Biol Neoplasia 13(1):93-103.
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , Issue.1 , pp. 93-103
    • Wagner, K.U.1    Rui, H.2
  • 144
    • 0028217452 scopus 로고
    • Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response
    • Wakao H, Gouilleux F, Groner B. 1994. Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response. EMBO J 13(9):2182-2191.
    • (1994) EMBO J , vol.13 , Issue.9 , pp. 2182-2191
    • Wakao, H.1    Gouilleux, F.2    Groner, B.3
  • 145
    • 84888302680 scopus 로고    scopus 로고
    • Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancer
    • Walker SR, Xiang M, Frank DA. 2014. Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancer. Mol Cell Endocrinol 382(1):616-621.
    • (2014) Mol Cell Endocrinol , vol.382 , Issue.1 , pp. 616-621
    • Walker, S.R.1    Xiang, M.2    Frank, D.A.3
  • 146
    • 0037936545 scopus 로고    scopus 로고
    • Essential functions of p21-activated kinase 1 in morphogenesis and differentiation of mammary glands
    • Wang RA, et al. 2003. Essential functions of p21-activated kinase 1 in morphogenesis and differentiation of mammary glands. J Cell Biol 161(3):583-592.
    • (2003) J Cell Biol , vol.161 , Issue.3 , pp. 583-592
    • Wang, R.A.1
  • 147
    • 0029784886 scopus 로고    scopus 로고
    • Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines
    • Weber-Nordt RM, et al. 1996. Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines. Blood 88(3):809-816.
    • (1996) Blood , vol.88 , Issue.3 , pp. 809-816
    • Weber-Nordt, R.M.1
  • 148
    • 33744490974 scopus 로고    scopus 로고
    • Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model
    • Wernig G, et al. 2006. Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model. Blood 107(11):4274-4281.
    • (2006) Blood , vol.107 , Issue.11 , pp. 4274-4281
    • Wernig, G.1
  • 149
    • 0035029411 scopus 로고    scopus 로고
    • Truncated STAT proteins are prevalent at relapse of acute myeloid leukemia
    • Xia Z, et al. 2001. Truncated STAT proteins are prevalent at relapse of acute myeloid leukemia. Leuk Res 25(6):473-482.
    • (2001) Leuk Res , vol.25 , Issue.6 , pp. 473-482
    • Xia, Z.1
  • 150
    • 0029786991 scopus 로고    scopus 로고
    • Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor
    • Xu BC, et al. 1996. Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor. J Biol Chem 271(33):19768-19773.
    • (1996) J Biol Chem , vol.271 , Issue.33 , pp. 19768-19773
    • Xu, B.C.1
  • 151
    • 42649118836 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases in the JAK/STAT pathway
    • Xu D, Qu CK. 2008. Protein tyrosine phosphatases in the JAK/STAT pathway. Front Biosci 13:4925-4932.
    • (2008) Front Biosci , vol.13 , pp. 4925-4932
    • Xu, D.1    Qu, C.K.2
  • 152
    • 0032515146 scopus 로고    scopus 로고
    • Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells
    • Yamashita H, et al. 1998. Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells. J Biol Chem 273(46):30218-30224.
    • (1998) J Biol Chem , vol.273 , Issue.46 , pp. 30218-30224
    • Yamashita, H.1
  • 153
    • 0035950441 scopus 로고    scopus 로고
    • Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression
    • Yamashita H, et al. 2001. Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression. Mol Cell Endocrinol 183(1-2):151-163.
    • (2001) Mol Cell Endocrinol , vol.183 , Issue.1-2 , pp. 151-163
    • Yamashita, H.1
  • 154
    • 0037457078 scopus 로고    scopus 로고
    • Naturally occurring dominantnegative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells
    • Yamashita H, et al. 2003. Naturally occurring dominantnegative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells. Oncogene 22(11):1638-1652.
    • (2003) Oncogene , vol.22 , Issue.11 , pp. 1638-1652
    • Yamashita, H.1
  • 155
    • 33751097277 scopus 로고    scopus 로고
    • Stat5 expression predicts response to endocrine therapy and improves survival in estrogen receptor-positive breast cancer
    • Yamashita H, et al. 2006. Stat5 expression predicts response to endocrine therapy and improves survival in estrogen receptor-positive breast cancer. Endocr Relat Cancer 13(3): 885-893.
    • (2006) Endocr Relat Cancer , vol.13 , Issue.3 , pp. 885-893
    • Yamashita, H.1
  • 156
    • 32244444750 scopus 로고    scopus 로고
    • Stat5a/b are essential for normal lymphoid development and differentiation
    • Yao Z, et al. 2006. Stat5a/b are essential for normal lymphoid development and differentiation. Proc Natl Acad Sci USA 103(4):1000-1005.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.4 , pp. 1000-1005
    • Yao, Z.1
  • 157
    • 33745057158 scopus 로고    scopus 로고
    • STAT5 signaling is required for the efficient induction and maintenance of CML in mice
    • Ye D, et al. 2006. STAT5 signaling is required for the efficient induction and maintenance of CML in mice. Blood 107(12): 4917-4925.
    • (2006) Blood , vol.107 , Issue.12 , pp. 4917-4925
    • Ye, D.1
  • 158
    • 0034916898 scopus 로고    scopus 로고
    • Involvement of protein phosphatase 2A in the interleukin-3-stimulated Jak2-Stat5 signaling pathway
    • Yokoyama N, ReichNC, MillerWT. 2001. Involvement of protein phosphatase 2A in the interleukin-3-stimulated Jak2-Stat5 signaling pathway. J Interferon Cytokine Res 21(6):369-378.
    • (2001) J Interferon Cytokine Res , vol.21 , Issue.6 , pp. 369-378
    • Yokoyama, N.1    Reich, N.C.2    Miller, W.T.3
  • 159
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • Yu H, Pardoll D, Jove R. 2009. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 9(11):798-809.
    • (2009) Nat Rev Cancer , vol.9 , Issue.11 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 160
    • 0030449174 scopus 로고    scopus 로고
    • Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling
    • Zhang JJ, et al. 1996. Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proc Natl Acad Sci USA 93(26):15092-15096.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.26 , pp. 15092-15096
    • Zhang, J.J.1
  • 161
    • 0035823547 scopus 로고    scopus 로고
    • Functional importance of Stat3 tetramerization in activation of the alpha 2-macroglobulin gene
    • Zhang X, Darnell JE, Jr. 2001. Functional importance of Stat3 tetramerization in activation of the alpha 2-macroglobulin gene. J Biol Chem 276(36):33576-33581.
    • (2001) J Biol Chem , vol.276 , Issue.36 , pp. 33576-33581
    • Zhang, X.1    Darnell, Jr.J.E.2
  • 162
    • 0344064893 scopus 로고    scopus 로고
    • Stat5 activation plays a critical role in Th2 differentiation
    • Zhu J, et al. 2003. Stat5 activation plays a critical role in Th2 differentiation. Immunity 19(5):739-748.
    • (2003) Immunity , vol.19 , Issue.5 , pp. 739-748
    • Zhu, J.1
  • 163
    • 77958611660 scopus 로고    scopus 로고
    • Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors
    • Zhu J, Paul WE. 2010. Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. Immunol Rev 238(1):247-262.
    • (2010) Immunol Rev , vol.238 , Issue.1 , pp. 247-262
    • Zhu, J.1    Paul, W.E.2
  • 164
    • 0033534562 scopus 로고    scopus 로고
    • Functional association of Nmi with Stat5 and Stat1 in IL-2-and IFNgamma-mediated signaling
    • Zhu M, et al. 1999. Functional association of Nmi with Stat5 and Stat1 in IL-2-and IFNgamma-mediated signaling. Cell 96(1):121-130.
    • (1999) Cell , vol.96 , Issue.1 , pp. 121-130
    • Zhu, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.