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Volumn 107, Issue 11, 2006, Pages 4274-4281

Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; JANUS KINASE 2; JANUS KINASE 2 V617F; STAT PROTEIN; UNCLASSIFIED DRUG;

EID: 33744490974     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-12-4824     Document Type: Article
Times cited : (414)

References (25)
  • 1
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144-1148.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 2
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005;7:387-397.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3
  • 3
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet. 2005;365:1054-1061.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3
  • 4
    • 17644424955 scopus 로고    scopus 로고
    • A gain-of-function mutation of JAK2 in myeloproliferative disorders
    • Kralovics R, Passamonti F, Buser AS, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med. 2005;352:1779-1790.
    • (2005) N Engl J Med , vol.352 , pp. 1779-1790
    • Kralovics, R.1    Passamonti, F.2    Buser, A.S.3
  • 5
    • 25844447519 scopus 로고    scopus 로고
    • JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosomenegative CML, and megakaryocytic leukemia
    • Jelinek J, Oki Y, Gharibyan V, et al. JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosomenegative CML, and megakaryocytic leukemia. Blood. 2005;106:3370-3373.
    • (2005) Blood , vol.106 , pp. 3370-3373
    • Jelinek, J.1    Oki, Y.2    Gharibyan, V.3
  • 6
    • 21344467318 scopus 로고    scopus 로고
    • Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders
    • Jones AV, Kreil S, Zoi K, et al. Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood. 2005;106:2162-2168.
    • (2005) Blood , vol.106 , pp. 2162-2168
    • Jones, A.V.1    Kreil, S.2    Zoi, K.3
  • 7
    • 0019201084 scopus 로고
    • Clonal origin and trisomy of chromosome 15 in murine B-cell malignancies
    • Fialkow PJ, Reddy AL, Bryant JI. Clonal origin and trisomy of chromosome 15 in murine B-cell malignancies. Int J Cancer. 1980;26:603-608.
    • (1980) Int J Cancer , vol.26 , pp. 603-608
    • Fialkow, P.J.1    Reddy, A.L.2    Bryant, J.I.3
  • 8
    • 15844431788 scopus 로고    scopus 로고
    • Conventional cytogenetics of myeloproliferative diseases other than CML contribute valid information
    • Bacher U, Haferlach T, Kern W, Hiddemann W, Schnittger S, Schoch C. Conventional cytogenetics of myeloproliferative diseases other than CML contribute valid information. Ann Hematol. 2005;84:250-257.
    • (2005) Ann Hematol , vol.84 , pp. 250-257
    • Bacher, U.1    Haferlach, T.2    Kern, W.3    Hiddemann, W.4    Schnittger, S.5    Schoch, C.6
  • 9
    • 0001639195 scopus 로고
    • Some speculations on the myeloproliferative syndromes
    • Dameshek W. Some speculations on the myeloproliferative syndromes. Blood. 1951;6:372-375.
    • (1951) Blood , vol.6 , pp. 372-375
    • Dameshek, W.1
  • 10
    • 0027454606 scopus 로고
    • Transcriptional analysis of the active X-chromosome in normal and clonal hematopoiesis
    • Prchal JT, Guan YL, Prchal JF, Barany F. Transcriptional analysis of the active X-chromosome in normal and clonal hematopoiesis. Blood. 1993;81:269-271.
    • (1993) Blood , vol.81 , pp. 269-271
    • Prchal, J.T.1    Guan, Y.L.2    Prchal, J.F.3    Barany, F.4
  • 12
    • 19344362958 scopus 로고    scopus 로고
    • On the molecular origins of the chronic myeloproliferative disorders: It all makes sense
    • Kaushansky K. On the molecular origins of the chronic myeloproliferative disorders: it all makes sense. Blood. 2005;105:4187-4190.
    • (2005) Blood , vol.105 , pp. 4187-4190
    • Kaushansky, K.1
  • 13
    • 0016391236 scopus 로고
    • Bone-marrow responses in polycythemia vera
    • Prchal JF, Axelrad AA. Bone-marrow responses in polycythemia vera [letter]. N Engl J Med. 1974;290:1382.
    • (1974) N Engl J Med , vol.290 , pp. 1382
    • Prchal, J.F.1    Axelrad, A.A.2
  • 14
    • 0023517121 scopus 로고
    • The significance of endogenous erythroid colonies (EEC) in haematological disorders
    • Reid CD. The significance of endogenous erythroid colonies (EEC) in haematological disorders. Blood Rev. 1987;1:133-140.
    • (1987) Blood Rev , vol.1 , pp. 133-140
    • Reid, C.D.1
  • 15
    • 0038281343 scopus 로고    scopus 로고
    • Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin
    • Liu E, Jelinek J, Pastore YD, Guan Y, Prchal JF, Prchal JT. Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin. Blood. 2003;101:3294-3301.
    • (2003) Blood , vol.101 , pp. 3294-3301
    • Liu, E.1    Jelinek, J.2    Pastore, Y.D.3    Guan, Y.4    Prchal, J.F.5    Prchal, J.T.6
  • 16
    • 0032076542 scopus 로고    scopus 로고
    • Jak2 is essential for signaling through a variety of cytokine receptors
    • Parganas E, Wang D, Stravopodis D, et al. Jak2 is essential for signaling through a variety of cytokine receptors. Cell. 1998;93:385-395.
    • (1998) Cell , vol.93 , pp. 385-395
    • Parganas, E.1    Wang, D.2    Stravopodis, D.3
  • 17
    • 18244432009 scopus 로고    scopus 로고
    • Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
    • Neubauer H, Cumano A, Muller M, Wu H, Huffstadt U, Pfeffer K. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell. 1998;93:397-409.
    • (1998) Cell , vol.93 , pp. 397-409
    • Neubauer, H.1    Cumano, A.2    Muller, M.3    Wu, H.4    Huffstadt, U.5    Pfeffer, K.6
  • 18
    • 0032530972 scopus 로고    scopus 로고
    • Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
    • Schwaller J, Frantsve J, Aster J, et al. Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO J. 1998;17:5321-5333.
    • (1998) EMBO J , vol.17 , pp. 5321-5333
    • Schwaller, J.1    Frantsve, J.2    Aster, J.3
  • 19
    • 0036093475 scopus 로고    scopus 로고
    • FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model
    • Kelly LM, Liu Q, Kutok JL, Williams IR, Boulton CL, Gilliland DG. FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model. Blood. 2002;99:310-318.
    • (2002) Blood , vol.99 , pp. 310-318
    • Kelly, L.M.1    Liu, Q.2    Kutok, J.L.3    Williams, I.R.4    Boulton, C.L.5    Gilliland, D.G.6
  • 20
    • 0021320037 scopus 로고
    • Two-color flow cytometric measurement of DNA distributions of rat megakaryocytes in unfixed, unfractionated marrow cell suspensions
    • Jackson CW, Brown LK, Somerville BC, Lyles SA, Look AT. Two-color flow cytometric measurement of DNA distributions of rat megakaryocytes in unfixed, unfractionated marrow cell suspensions. Blood. 1984;63:768-778.
    • (1984) Blood , vol.63 , pp. 768-778
    • Jackson, C.W.1    Brown, L.K.2    Somerville, B.C.3    Lyles, S.A.4    Look, A.T.5
  • 21
    • 22144447520 scopus 로고    scopus 로고
    • Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype
    • Growney JD, Shigematsu H, Li Z, et al. Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype. Blood. 2005;106:494-504.
    • (2005) Blood , vol.106 , pp. 494-504
    • Growney, J.D.1    Shigematsu, H.2    Li, Z.3
  • 22
    • 8444243255 scopus 로고    scopus 로고
    • Enhancer role of STAT5 in CD2 activation of IFN-gamma gene expression
    • Gonsky R, Deem RL, Bream J, Young HA, Targan SR. Enhancer role of STAT5 in CD2 activation of IFN-gamma gene expression. J Immunol. 2004;173:6241-6247.
    • (2004) J Immunol , vol.173 , pp. 6241-6247
    • Gonsky, R.1    Deem, R.L.2    Bream, J.3    Young, H.A.4    Targan, S.R.5
  • 23
    • 19644392085 scopus 로고    scopus 로고
    • Diagnostic value of serum erythropoietin level in patients with absolute erythrocytosis
    • Mossuz P, Girodon F, Donnard M, et al. Diagnostic value of serum erythropoietin level in patients with absolute erythrocytosis. Haematologica. 2004;89:1194-1198.
    • (2004) Haematologica , vol.89 , pp. 1194-1198
    • Mossuz, P.1    Girodon, F.2    Donnard, M.3
  • 24
    • 25844461158 scopus 로고    scopus 로고
    • The Jak2V617F mutation, PRV-1 overexpression, and EEC formation define a similar cohort of MPD patients
    • Goerttler PS, Steimle C, Marz E, et al. The Jak2V617F mutation, PRV-1 overexpression, and EEC formation define a similar cohort of MPD patients. Blood. 2005;106:2862-2864.
    • (2005) Blood , vol.106 , pp. 2862-2864
    • Goerttler, P.S.1    Steimle, C.2    Marz, E.3
  • 25
    • 30044437118 scopus 로고    scopus 로고
    • Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation
    • U S A
    • Lu X, Levine R, Tong W, et al. Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation. Proc Natl Acad Sci U S A. 2005;102:18962-18967.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 18962-18967
    • Lu, X.1    Levine, R.2    Tong, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.