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Volumn 15, Issue 20, 1996, Pages 5616-5626

DNA binding of in vitro activated Stat1α, Stat1β and truncated Stat1: Interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites

Author keywords

Cooperative DNA binding; N terminus; Phosphoprotein; Proteolysis; Stat1

Indexed keywords

PHOSPHOPROTEIN; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR;

EID: 0029903770     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00946.x     Document Type: Article
Times cited : (256)

References (33)
  • 2
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. (1976) A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-251.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-251
    • Bradford, M.M.1
  • 4
    • 0029979976 scopus 로고    scopus 로고
    • Influence of matrix solution conditions on the MALDI-MS analysis of peptides and proteins
    • Cohen, S.L. and Chait, B.T. (1996) Influence of matrix solution conditions on the MALDI-MS analysis of peptides and proteins. Anal. Chem., 68, 31-37.
    • (1996) Anal. Chem. , vol.68 , pp. 31-37
    • Cohen, S.L.1    Chait, B.T.2
  • 5
    • 0029004044 scopus 로고
    • Probing the solution structure of the DNA-binding protein Max by a combination of proteolysis and mass spectrometry
    • Cohen, S.L., Ferre-D'Amare, A.R., Burley, S.K. and Chait, B.T. (1995) Probing the solution structure of the DNA-binding protein Max by a combination of proteolysis and mass spectrometry. Protein Sci., 4, 1088-1099.
    • (1995) Protein Sci. , vol.4 , pp. 1088-1099
    • Cohen, S.L.1    Ferre-D'Amare, A.R.2    Burley, S.K.3    Chait, B.T.4
  • 6
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell, J.E.,Jr, Kerr, I.M. and Stark, G.M. (1994) Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science, 264, 1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.M.3
  • 7
    • 0019878376 scopus 로고
    • Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis
    • Fried, M. and Crothers, D.M. (1981) Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. Nucleic Acids Res., 9, 6505-6525.
    • (1981) Nucleic Acids Res. , vol.9 , pp. 6505-6525
    • Fried, M.1    Crothers, D.M.2
  • 8
    • 0026723419 scopus 로고
    • A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s)
    • Fu, X.-Y. (1992) A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s). Cell, 70, 323-335.
    • (1992) Cell , vol.70 , pp. 323-335
    • Fu, X.-Y.1
  • 9
    • 0019877067 scopus 로고
    • A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: Application to components of the Escherichia coli lactose operon regulatory system
    • Garner, M.M. and Revzin, A. (1981) A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system. Nucleic Acids Res., 9, 3047-3060.
    • (1981) Nucleic Acids Res. , vol.9 , pp. 3047-3060
    • Garner, M.M.1    Revzin, A.2
  • 11
    • 0028983210 scopus 로고
    • IFN-γ induces a p91/Stat1α-related transcription factor with distinct activation and binding properties
    • Guyer, N.B., Severns, C.W., Wong, P., Feghali, C.A. and Wright, T.M. (1995) IFN-γ induces a p91/Stat1α-related transcription factor with distinct activation and binding properties. J. Immunol., 155, 3472-3480.
    • (1995) J. Immunol. , vol.155 , pp. 3472-3480
    • Guyer, N.B.1    Severns, C.W.2    Wong, P.3    Feghali, C.A.4    Wright, T.M.5
  • 12
    • 0028913109 scopus 로고
    • A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
    • Horvath, C.M., Wen, Z. and Darnell, J.E.,Jr (1995) A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev., 9, 984-994.
    • (1995) Genes Dev. , vol.9 , pp. 984-994
    • Horvath, C.M.1    Wen, Z.2    Darnell Jr., J.E.3
  • 13
    • 0028845212 scopus 로고
    • Cytokine receptor signalling
    • Ihle, J.N. (1995) Cytokine receptor signalling. Nature, 377, 591-594.
    • (1995) Nature , vol.377 , pp. 591-594
    • Ihle, J.N.1
  • 14
    • 0023953283 scopus 로고
    • Direct protein microsequencing from Immobilon-P transfer membrane
    • LeGendre, N. and Matsudaira, P. (1988) Direct protein microsequencing from Immobilon-P transfer membrane. Biotechniques, 6, 154-159.
    • (1988) Biotechniques , vol.6 , pp. 154-159
    • LeGendre, N.1    Matsudaira, P.2
  • 15
    • 0024721567 scopus 로고
    • Cytoplasmic activation of ISGF3, the positive regulator of interferon-α stimulated transcription, reconstituted in vitro
    • Levy, D.E., Kessler, D.S., Pine, R.I. and Darnell, J.E.,Jr (1989) Cytoplasmic activation of ISGF3, the positive regulator of interferon-α stimulated transcription, reconstituted in vitro. Genes Dev., 3, 1362-1372.
    • (1989) Genes Dev. , vol.3 , pp. 1362-1372
    • Levy, D.E.1    Kessler, D.S.2    Pine, R.I.3    Darnell Jr., J.E.4
  • 16
    • 0027434082 scopus 로고
    • Complementation of a mutant cell line: Central role of the 91-kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathway
    • Muller, M., Laxton, C., Briscoe, J., Schindler, C., Improta, J., Darnell, J.E.,Jr, Stark, G.R. and Kerr, I.M. (1993) Complementation of a mutant cell line: Central role of the 91-kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathway. EMBO J., 12, 4221-4228.
    • (1993) EMBO J. , vol.12 , pp. 4221-4228
    • Muller, M.1    Laxton, C.2    Briscoe, J.3    Schindler, C.4    Improta, J.5    Darnell Jr., J.E.6    Stark, G.R.7    Kerr, I.M.8
  • 17
    • 0029133520 scopus 로고
    • Phosphorylation and activation of the DNA binding activity of purified Stal1 by the Janus protein tyrosine kinases and epidermal growth factor receptor
    • Quelle, F.W., Thierfelder, W., Witthuhn, B.A., Tang, B., Cohen, S. and Ihle, J.N. (1995) Phosphorylation and activation of the DNA binding activity of purified Stal1 by the Janus protein tyrosine kinases and epidermal growth factor receptor. J. Biol. Chem., 270, 20775-20780.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20775-20780
    • Quelle, F.W.1    Thierfelder, W.2    Witthuhn, B.A.3    Tang, B.4    Cohen, S.5    Ihle, J.N.6
  • 18
    • 0029061508 scopus 로고
    • Tyrosine phosphorylated Stat1 and Stat2 plus a 48 kDa protein all contact DNA in forming the interferon stimulated gene factor 3 (ISGF3)
    • Qureshi, S.A., Salditt-Georgieff, M. and Darnell, J.E.,Jr (1995) Tyrosine phosphorylated Stat1 and Stat2 plus a 48 kDa protein all contact DNA in forming the interferon stimulated gene factor 3 (ISGF3) Proc. Natl Acad. Sci. USA, 92, 3929-3833.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 3929-13833
    • Qureshi, S.A.1    Salditt-Georgieff, M.2    Darnell Jr., J.E.3
  • 19
    • 0014965617 scopus 로고
    • lac repressor-operator interaction. I. Equilibrium studies
    • Riggs, A.D., Suzuki, H. and Bourgeois, S. (1970) lac repressor-operator interaction. I. Equilibrium studies. J. Mol. Biol., 48, 67-83.
    • (1970) J. Mol. Biol. , vol.48 , pp. 67-83
    • Riggs, A.D.1    Suzuki, H.2    Bourgeois, S.3
  • 20
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler, C. and Darnell, J.E.,Jr (1995) Transcriptional responses to polypeptide ligands: The JAK-STAT pathway. Annu. Rev. Biochem., 64, 621-51.
    • (1995) Annu. Rev. Biochem. , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell Jr., J.E.2
  • 21
    • 0026725868 scopus 로고
    • Proteins of transcription factor ISGF-3: One gene encodes the 91 and 84 kDa ISGF-3 proteins that are activated by inteferon-α
    • Schindler, C., Fu, X.-Y., Improta, T., Aebersold, R. and Darnell, J.E.,Jr (1992) Proteins of transcription factor ISGF-3: One gene encodes the 91 and 84 kDa ISGF-3 proteins that are activated by inteferon-α. Proc. Natl Acad. Sci. USA, 89, 7836-7839.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 7836-7839
    • Schindler, C.1    Fu, X.-Y.2    Improta, T.3    Aebersold, R.4    Darnell Jr., J.E.5
  • 22
    • 0027090310 scopus 로고
    • Activation of transcription by IFN-γ: Tyrosine phosphorylation of a 91 kDa DNA binding protein
    • Shuai, K., Schindler, C., Prezioso, V.R. and Darnell, J.E.,Jr (1992) Activation of transcription by IFN-γ: tyrosine phosphorylation of a 91 kDa DNA binding protein. Science, 259, 1808-1812.
    • (1992) Science , vol.259 , pp. 1808-1812
    • Shuai, K.1    Schindler, C.2    Prezioso, V.R.3    Darnell Jr., J.E.4
  • 23
    • 0027493650 scopus 로고
    • A single phosphotyrosine residue of Stat91 required for gene activation by interferon-γ
    • Shuai, K., Stark, G.R., Kerr, I.M. and Darnell, J.E.,Jr (1993a) A single phosphotyrosine residue of Stat91 required for gene activation by interferon-γ. Science, 261, 1744-1746.
    • (1993) Science , vol.261 , pp. 1744-1746
    • Shuai, K.1    Stark, G.R.2    Kerr, I.M.3    Darnell Jr., J.E.4
  • 25
    • 0028349904 scopus 로고
    • Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
    • Shuai, K., Horvath, C.M., Tsai-Huang, L.H., Qureshi, S., Cowburn, D. and Darnell, J.E.,Jr (1994) Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell, 76, 821-828.
    • (1994) Cell , vol.76 , pp. 821-828
    • Shuai, K.1    Horvath, C.M.2    Tsai-Huang, L.H.3    Qureshi, S.4    Cowburn, D.5    Darnell Jr., J.E.6
  • 26
    • 0004876612 scopus 로고
    • Qualitative and quantitative studies of protein-DNA interactions by gel mobility-shift assay
    • Jost, J.P. and Saluz, H.P. (eds)
    • Stone, S.R., Hughes, M.J. and Jost, J.P. (1991) Qualitative and quantitative studies of protein-DNA interactions by gel mobility-shift assay. In Jost, J.P. and Saluz, H.P. (eds), A Laboratory Guide to In Vitro Studies of Protein-DNA Interactions, BioMethods. Vol. 5, pp. 163-195.
    • (1991) A Laboratory Guide to in Vitro Studies of Protein-DNA Interactions, BioMethods , vol.5 , pp. 163-195
    • Stone, S.R.1    Hughes, M.J.2    Jost, J.P.3
  • 27
    • 0023042283 scopus 로고
    • Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
    • Studier, F.W. and Moffatt, B.A. (1986) Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol., 189, 113-130.
    • (1986) J. Mol. Biol. , vol.189 , pp. 113-130
    • Studier, F.W.1    Moffatt, B.A.2
  • 28
    • 0025639009 scopus 로고
    • The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter
    • Wagner, B.J., Hayes, T.E., Hoban, C.J. and Cochran, B.H. (1990) The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J., 9, 4477-4484.
    • (1990) EMBO J. , vol.9 , pp. 4477-4484
    • Wagner, B.J.1    Hayes, T.E.2    Hoban, C.J.3    Cochran, B.H.4
  • 29
    • 0029117304 scopus 로고
    • Maximal activation of transcription of Stal1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen, Z., Zhong, Z. and Darnell, J.E.,Jr (1995) Maximal activation of transcription of Stal1 and Stat3 requires both tyrosine and serine phosphorylation. Cell, 82, 241-250.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 30
    • 0029670220 scopus 로고    scopus 로고
    • Phosphorylated interferon-α receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein
    • Yan, H., Krishnan, K., Greenlund, A.C., Gupta, S., Lim, J.T.E., Schreiber, R.D., Schindler, C.W. and Krolewski, J.J. (1996) Phosphorylated interferon-α receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein. EMBO J., 15, 1064-1074.
    • (1996) EMBO J. , vol.15 , pp. 1064-1074
    • Yan, H.1    Krishnan, K.2    Greenlund, A.C.3    Gupta, S.4    Lim, J.T.E.5    Schreiber, R.D.6    Schindler, C.W.7    Krolewski, J.J.8
  • 31
    • 0028931589 scopus 로고
    • The genomic structure of the STAT genes: Multiple exons in coincident sites in Stat1 and Stat2
    • Yan, R., Qureshi, S., Zhong, Z., Wen, Z. and Darnell, J.E.,Jr (1995) The genomic structure of the STAT genes: Multiple exons in coincident sites in Stat1 and Stat2. Nucleic Acids Res., 23, 459-463.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 459-463
    • Yan, R.1    Qureshi, S.2    Zhong, Z.3    Wen, Z.4    Darnell Jr., J.E.5
  • 32
    • 0001514956 scopus 로고    scopus 로고
    • Identification of a Stat gene that functions in Drosophila development
    • Yan, R., Small, S., Desplan, C., Dearolf, C.R. and Darnell, J.E.,Jr (1996) Identification of a Stat gene that functions in Drosophila development. Cell, 84, 421-430.
    • (1996) Cell , vol.84 , pp. 421-430
    • Yan, R.1    Small, S.2    Desplan, C.3    Dearolf, C.R.4    Darnell Jr., J.E.5
  • 33
    • 0021943782 scopus 로고
    • Purification of an active EGF receptor kinase with monoclonal antireceptor antibodies
    • Yarden, Y., Harari, I. and Schlessinger, J. (1985) Purification of an active EGF receptor kinase with monoclonal antireceptor antibodies. J. Biol. Chem., 260, 315-319.
    • (1985) J. Biol. Chem. , vol.260 , pp. 315-319
    • Yarden, Y.1    Harari, I.2    Schlessinger, J.3


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