Regulation of mitochondrial genome replication by hypoxia: The role of DNA oxidation in D-loop region

Free Radical Biology and Medicine

Volumn 96, Issue , 2016, Pages 78-88

  Pastukh, Viktor M ^a   Gorodnya, Olena M ^a   Gillespie, Mark N ^a   Ruchko, Mykhaylo V ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

D loop; Hypoxia; Mitochondrial DNA replication; Ogg1 overexpression; Oxidative DNA modifications; Reactive oxygen species; TFAM binding

Indexed keywords

MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PROTEIN OGG1; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DNA GLYCOSYLTRANSFERASE; OGG1 PROTEIN, RAT; REACTIVE OXYGEN METABOLITE; TFAM PROTEIN, RAT; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; DNA SEQUENCE; ENDOTHELIUM CELL; HYPOXIC CELL; MITOCHONDRIAL DNA REPLICATION; MITOCHONDRIAL GENOME; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROMOTER REGION; PULMONARY ARTERY; RAT; REGULATORY MECHANISM; ANIMAL; CELL PROLIFERATION; DNA DAMAGE; DNA REPLICATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MITOCHONDRION; ORGANELLE BIOGENESIS; OXIDATIVE STRESS; PATHOLOGY;

ANIMALS; CELL HYPOXIA; CELL PROLIFERATION; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPLICATION; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GENOME, MITOCHONDRIAL; HUMANS; MITOCHONDRIA; ORGANELLE BIOGENESIS; OXIDATIVE STRESS; PULMONARY ARTERY; RATS; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTORS;

EID: 84964211327     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2016.04.011     Document Type: Article

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