Impact of hypoxia and long-term cultivation on the genomic stability and mitochondrial performance of ex vivo expanded human stem/stromal cells

Stem Cell Research

Volumn 9, Issue 3, 2012, Pages 225-236

  Oliveira, Pedro H ^a   Boura, Joana S ^a   Abecasis, Manuel M ^b   Gimble, Jeffrey M ^c   da Silva, Cláudia Lobato ^a   Cabral, Joaquim M S ^a  

^a INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^b INSTITUTO PORTUGUÊS DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL   (Portugal)

^c PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; MITOCHONDRIAL DNA;

ARTICLE; DNA CONTENT; DNA REPAIR; DOWN REGULATION; GENE MUTATION; GENOMIC INSTABILITY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; MICROSATELLITE INSTABILITY; MITOCHONDRIAL GENOME; MITOCHONDRION; PRIORITY JOURNAL; TELOMERE;

ADENOSINE TRIPHOSPHATE; ADIPOCYTES; ADULT; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; GENOMIC INSTABILITY; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; MITOCHONDRIA; OXYGEN; TELOMERE; TIME FACTORS;

EID: 84864954257     PISSN: 18735061     EISSN: 18767753     Source Type: Journal    
DOI: 10.1016/j.scr.2012.07.001     Document Type: Article

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